IMP: Integrative Multi-species Prediction

Drosophila melanogaster

95 known processes

Axn (Dmel_CG7926)

Axin

(Aliases: dAxin,dAXIN,axin,d-axin,0442/30,DAxin,din,D-Axin,Dmel\CG7926,Daxin,CG7926,axn,l(3)S044230)

FLYBASE: FBgn0026597
Entrez: 43565
UniProtKB: Q9V407
UniProtKB: B7Z0S0
UniProtKB: E1JJ18
UniProtKB: Q8IMJ7
UniProtKB: A4V3M5

Process Predictions
Disease Predictions

Axn biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
muscle structure development	GO:0061061	224	0.995	Zebrafish
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.969	Mouse
transcription from rna polymerase ii promoter	GO:0006366	368	0.899	Mouse
nuclear division	GO:0000280	332	0.793
chromosome segregation	GO:0007059	157	0.784	Human Mouse
regulation of multicellular organismal development	GO:2000026	414	0.780	Human Mouse Worm
positive regulation of rna biosynthetic process	GO:1902680	266	0.770	Human Mouse
muscle organ development	GO:0007517	127	0.725
positive regulation of signal transduction	GO:0009967	223	0.713	Zebrafish Mouse
catabolic process	GO:0009056	409	0.711	Human Mouse
organelle fission	GO:0048285	340	0.688
regulation of cell cycle phase transition	GO:1901987	130	0.608
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.559
imaginal disc derived appendage development	GO:0048737	399	0.547
regulation of wnt signaling pathway	GO:0030111	68	0.537
positive regulation of gene expression	GO:0010628	290	0.512	Human Mouse
regulation of organ growth	GO:0046620	42	0.457
positive regulation of cellular biosynthetic process	GO:0031328	316	0.429	Human Mouse
meiotic cell cycle	GO:0051321	171	0.427
positive regulation of rna metabolic process	GO:0051254	271	0.375	Human Mouse
immune system process	GO:0002376	347	0.374	Mouse
imaginal disc derived wing margin morphogenesis	GO:0008587	41	0.372
positive regulation of macromolecule metabolic process	GO:0010604	405	0.351	Human Zebrafish Mouse
positive regulation of response to stimulus	GO:0048584	323	0.350	Zebrafish Mouse
sister chromatid segregation	GO:0000819	92	0.340
meiotic cell cycle process	GO:1903046	132	0.331
regulation of transport	GO:0051049	181	0.330	Human Mouse
covalent chromatin modification	GO:0016569	106	0.320
regulation of anatomical structure morphogenesis	GO:0022603	242	0.319	Human
regulation of cell cycle process	GO:0010564	181	0.316	Human Mouse
positive regulation of stem cell differentiation	GO:2000738	3	0.314	Human
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.304	Human Mouse
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.302	Human Mouse
tube development	GO:0035295	244	0.288	Mouse
imaginal disc growth	GO:0007446	37	0.288
regulation of mitotic cell cycle	GO:0007346	190	0.272
positive regulation of developmental process	GO:0051094	143	0.268	Human Worm
mitotic nuclear division	GO:0007067	213	0.266
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.250	Mouse
organ growth	GO:0035265	56	0.246
response to organic cyclic compound	GO:0014070	89	0.213
meiotic nuclear division	GO:0007126	151	0.202
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.192	Human Mouse
prostaglandin biosynthetic process	GO:0001516	1	0.190
spindle organization	GO:0007051	253	0.187	Worm
chromosome organization	GO:0051276	360	0.174	Human Mouse
respiratory system development	GO:0060541	213	0.174	Zebrafish
mitotic cell cycle embryonic	GO:0045448	38	0.173
developmental growth	GO:0048589	280	0.170	Zebrafish Worm
macromolecule catabolic process	GO:0009057	161	0.168	Human Mouse
organic substance catabolic process	GO:1901575	308	0.168	Human Mouse
positive regulation of transcription dna templated	GO:0045893	266	0.166	Human Mouse
regulation of protein import into nucleus	GO:0042306	28	0.163	Human Mouse
eye morphogenesis	GO:0048592	260	0.160	Zebrafish
digestive system development	GO:0055123	149	0.156	Mouse
positive regulation of protein import into nucleus	GO:0042307	21	0.154
mrna processing	GO:0006397	104	0.153
regulation of epithelial cell proliferation	GO:0050678	4	0.146
mitotic spindle organization	GO:0007052	220	0.134	Worm
post embryonic appendage morphogenesis	GO:0035120	385	0.132
regulation of intracellular protein transport	GO:0033157	46	0.127	Human Mouse
male gamete generation	GO:0048232	201	0.121
dorsal ventral pattern formation	GO:0009953	133	0.119	Zebrafish Mouse
axis specification	GO:0009798	167	0.119	Zebrafish Mouse Worm
heart field specification	GO:0003128	0	0.119	Mouse
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.117	Human Mouse
protein transport	GO:0015031	155	0.111	Human Mouse
proteolysis	GO:0006508	192	0.111	Mouse
positive regulation of signaling	GO:0023056	243	0.110	Zebrafish Mouse
histone modification	GO:0016570	106	0.104
positive regulation of nucleocytoplasmic transport	GO:0046824	24	0.104
dna conformation change	GO:0071103	105	0.103
protein localization to nucleus	GO:0034504	55	0.103	Human Mouse
multicellular organismal reproductive behavior	GO:0033057	110	0.103	Worm
positive regulation of protein localization to nucleus	GO:1900182	21	0.102
regulation of multi organism process	GO:0043900	131	0.101
nuclear import	GO:0051170	51	0.100	Human Mouse
imaginal disc derived leg morphogenesis	GO:0007480	80	0.100
cell proliferation	GO:0008283	299	0.099	Human Mouse
reproductive behavior	GO:0019098	122	0.097	Worm
eye development	GO:0001654	323	0.097	Zebrafish
leg disc morphogenesis	GO:0007478	80	0.097
appendage development	GO:0048736	401	0.097
dna metabolic process	GO:0006259	227	0.096	Human
positive regulation of multicellular organismal process	GO:0051240	143	0.096	Human Worm
mapk cascade	GO:0000165	107	0.095	Zebrafish Mouse
negative regulation of cell cycle phase transition	GO:1901988	103	0.091
meiosis i	GO:0007127	59	0.090
defense response to bacterium	GO:0042742	178	0.086
spermatogenesis	GO:0007283	200	0.086
positive regulation of developmental growth	GO:0048639	62	0.086	Worm
gonad development	GO:0008406	50	0.086	Worm
mesenchymal cell differentiation	GO:0048762	1	0.084	Human
wing disc morphogenesis	GO:0007472	344	0.082
phagocytosis	GO:0006909	215	0.080
positive regulation of cell development	GO:0010720	61	0.080	Human
body morphogenesis	GO:0010171	2	0.080
positive regulation of protein transport	GO:0051222	37	0.075
multi multicellular organism process	GO:0044706	123	0.074	Worm
cellular protein localization	GO:0034613	160	0.073	Human Mouse
muscle tissue development	GO:0060537	30	0.072
protein localization to organelle	GO:0033365	82	0.071	Human Mouse
response to biotic stimulus	GO:0009607	294	0.071
homeostatic process	GO:0042592	199	0.071	Mouse
asymmetric cell division	GO:0008356	37	0.070
regulation of localization	GO:0032879	275	0.069	Human Mouse Worm
dorsal ventral axis specification ovarian follicular epithelium	GO:0008069	13	0.069
chromatin modification	GO:0016568	147	0.068
regulation of cell differentiation	GO:0045595	302	0.067
organophosphate metabolic process	GO:0019637	195	0.065
nucleoside metabolic process	GO:0009116	127	0.063
cell division	GO:0051301	248	0.061
regulation of organ morphogenesis	GO:2000027	78	0.061
positive regulation of biosynthetic process	GO:0009891	316	0.059	Human Mouse
open tracheal system development	GO:0007424	204	0.058
negative regulation of epithelial cell proliferation	GO:0050680	4	0.058
protein import into nucleus	GO:0006606	51	0.057	Human Mouse
establishment of protein localization to organelle	GO:0072594	62	0.056	Human Mouse
sex differentiation	GO:0007548	81	0.055	Worm
protein targeting	GO:0006605	64	0.055	Human Mouse
cell motility	GO:0048870	251	0.055	Worm
organic cyclic compound catabolic process	GO:1901361	168	0.055
regulation of imaginal disc growth	GO:0045570	26	0.055
positive regulation of intracellular protein transport	GO:0090316	30	0.054
positive regulation of transport	GO:0051050	92	0.054
wnt signaling pathway	GO:0016055	98	0.054
retina development in camera type eye	GO:0060041	4	0.054
regulation of protein transport	GO:0051223	57	0.054	Human Mouse
single organism biosynthetic process	GO:0044711	206	0.054
dna packaging	GO:0006323	91	0.053
positive regulation of wnt signaling pathway	GO:0030177	25	0.053
negative regulation of wnt signaling pathway	GO:0030178	28	0.053
mitotic cytokinesis	GO:0000281	50	0.053
regulation of phosphorus metabolic process	GO:0051174	210	0.051	Human Zebrafish Mouse
regulation of protein localization	GO:0032880	76	0.051	Human Mouse Worm
dna integration	GO:0015074	1	0.051
embryo development ending in birth or egg hatching	GO:0009792	152	0.051	Zebrafish Mouse
establishment of localization in cell	GO:0051649	402	0.050	Human Mouse
macromolecular complex assembly	GO:0065003	256	0.049	Human Mouse
regulation of nucleocytoplasmic transport	GO:0046822	35	0.049	Human Mouse
axon guidance	GO:0007411	233	0.048	Worm
imaginal disc derived wing vein morphogenesis	GO:0008586	44	0.047
reproductive structure development	GO:0048608	74	0.046	Worm
negative regulation of cell cycle process	GO:0010948	109	0.046
cellular catabolic process	GO:0044248	372	0.046	Mouse
oocyte morphogenesis	GO:0048601	3	0.045
chromatin organization	GO:0006325	207	0.045
regulation of establishment of protein localization	GO:0070201	61	0.044	Human Mouse
negative regulation of programmed cell death	GO:0043069	72	0.044
regulation of dna metabolic process	GO:0051052	34	0.044	Human
blastoderm segmentation	GO:0007350	159	0.044
single organism nuclear import	GO:1902593	51	0.043	Human Mouse
regulation of intracellular signal transduction	GO:1902531	236	0.042	Zebrafish Mouse
instar larval development	GO:0002168	55	0.042
response to external biotic stimulus	GO:0043207	293	0.042
canonical wnt signaling pathway involved in heart development	GO:0061316	3	0.042
memory	GO:0007613	94	0.042
regulation of cellular localization	GO:0060341	136	0.041	Human Mouse
dorsal ventral axis specification	GO:0009950	66	0.041	Zebrafish Mouse
neuron projection guidance	GO:0097485	241	0.040	Worm
endodermal cell fate commitment	GO:0001711	3	0.039
growth	GO:0040007	359	0.039	Zebrafish Worm
intracellular protein transport	GO:0006886	104	0.039	Human Mouse
stem cell maintenance	GO:0019827	67	0.039
negative regulation of multicellular organismal process	GO:0051241	142	0.038	Mouse Worm
nucleobase containing small molecule metabolic process	GO:0055086	174	0.038
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.038
tracheal outgrowth open tracheal system	GO:0007426	18	0.036
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.036	Mouse
establishment or maintenance of polarity of follicular epithelium	GO:0016334	26	0.036
positive regulation of intracellular signal transduction	GO:1902533	116	0.036	Zebrafish Mouse
appendage morphogenesis	GO:0035107	397	0.034
brain development	GO:0007420	120	0.034	Zebrafish
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.034	Mouse
regulation of cell development	GO:0060284	215	0.034	Human Mouse
cellular response to organic substance	GO:0071310	132	0.034	Mouse
developmental growth involved in morphogenesis	GO:0060560	65	0.034
response to oxygen containing compound	GO:1901700	200	0.033
multi organism reproductive behavior	GO:0044705	121	0.032	Worm
organonitrogen compound metabolic process	GO:1901564	318	0.032
cytokinesis	GO:0000910	90	0.032
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encoded	GO:0008071	1	0.032
carbohydrate derivative metabolic process	GO:1901135	217	0.032
imaginal disc derived wing morphogenesis	GO:0007476	337	0.032
epithelial cell fate determination open tracheal system	GO:0007425	2	0.031
positive regulation of cellular component organization	GO:0051130	156	0.031	Human
cellular macromolecule localization	GO:0070727	220	0.031	Human Mouse
mrna metabolic process	GO:0016071	124	0.031
response to organic substance	GO:0010033	284	0.031	Mouse
molting cycle	GO:0042303	56	0.031
organelle localization	GO:0051640	148	0.031
small molecule metabolic process	GO:0044281	305	0.031
regulation of chromosome organization	GO:0033044	64	0.031	Human Mouse
vesicle mediated transport	GO:0016192	381	0.030
regulation of mapk cascade	GO:0043408	92	0.030	Zebrafish Mouse
endodermal cell differentiation	GO:0035987	3	0.030
nucleoside triphosphate metabolic process	GO:0009141	120	0.030
regulation of cellular protein metabolic process	GO:0032268	243	0.029	Human Zebrafish Mouse
regulation of cytoplasmic transport	GO:1903649	47	0.028	Human Mouse
negative regulation of cell communication	GO:0010648	223	0.028
wnt signaling pathway involved in heart development	GO:0003306	3	0.028
hindbrain development	GO:0030902	2	0.027
antimicrobial humoral response	GO:0019730	99	0.027
negative regulation of mitotic cell cycle	GO:0045930	109	0.027
cellular response to chemical stimulus	GO:0070887	199	0.026	Mouse
dna recombination	GO:0006310	32	0.026
cellular response to oxygen containing compound	GO:1901701	79	0.026
establishment of protein localization	GO:0045184	163	0.026	Human Mouse
protein catabolic process	GO:0030163	101	0.026	Human Mouse
single organism cellular localization	GO:1902580	180	0.025	Human Mouse
aromatic compound catabolic process	GO:0019439	166	0.025
protein complex assembly	GO:0006461	200	0.025	Human Mouse
regulation of cell proliferation involved in compound eye morphogenesis	GO:2000495	2	0.025
positive regulation of intracellular transport	GO:0032388	42	0.024
protein targeting to nucleus	GO:0044744	51	0.024	Human Mouse
segmentation	GO:0035282	207	0.024	Zebrafish Mouse
mitotic cell cycle phase transition	GO:0044772	138	0.024
mitotic sister chromatid segregation	GO:0000070	87	0.024
multi organism behavior	GO:0051705	175	0.024	Worm
positive regulation of chromatin silencing at telomere	GO:0031940	2	0.024
renal system development	GO:0072001	72	0.024
positive regulation of multi organism process	GO:0043902	40	0.024
nuclear migration	GO:0007097	20	0.023
response to alcohol	GO:0097305	95	0.023
protein modification process	GO:0036211	438	0.023	Human Zebrafish Mouse
oocyte fate commitment	GO:0048600	2	0.023
regulation of phosphate metabolic process	GO:0019220	210	0.022	Human Zebrafish Mouse
anatomical structure homeostasis	GO:0060249	97	0.022
single organism carbohydrate metabolic process	GO:0044723	72	0.022
meiotic spindle checkpoint	GO:0044779	1	0.022
positive regulation of organelle organization	GO:0010638	65	0.022
positive regulation of cell communication	GO:0010647	250	0.022	Zebrafish Mouse
cell death	GO:0008219	279	0.022	Human
spinal cord development	GO:0021510	1	0.021
humoral immune response	GO:0006959	117	0.021
maintenance of gastrointestinal epithelium	GO:0030277	3	0.021
cellular response to organic cyclic compound	GO:0071407	32	0.021
detection of virus	GO:0009597	1	0.021
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.021
icosanoid biosynthetic process	GO:0046456	1	0.021
regulation of protein metabolic process	GO:0051246	256	0.021	Human Zebrafish Mouse
protein complex biogenesis	GO:0070271	201	0.021	Human Mouse
positive regulation of catabolic process	GO:0009896	105	0.020	Human Mouse
negative regulation of cell cycle	GO:0045786	116	0.020
regulation of dna templated transcription elongation	GO:0032784	17	0.020	Mouse
meiotic nuclear envelope disassembly	GO:0051078	2	0.020
death	GO:0016265	284	0.020	Human
juvenile hormone mediated signaling pathway	GO:0035626	3	0.020
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.020
neuroblast proliferation	GO:0007405	74	0.020
organophosphate catabolic process	GO:0046434	112	0.020
male meiosis	GO:0007140	52	0.020
single organism catabolic process	GO:0044712	228	0.020
digestive tract morphogenesis	GO:0048546	127	0.020	Mouse
compound eye photoreceptor fate commitment	GO:0001752	36	0.020
regulation of catabolic process	GO:0009894	170	0.019	Human Mouse
defense response to other organism	GO:0098542	225	0.019
protein modification by small protein conjugation or removal	GO:0070647	106	0.019	Human Mouse
signal transduction by phosphorylation	GO:0023014	107	0.019	Zebrafish Mouse
macromolecule methylation	GO:0043414	45	0.019
carbohydrate derivative catabolic process	GO:1901136	118	0.019
intrinsic apoptotic signaling pathway	GO:0097193	16	0.019
camera type eye morphogenesis	GO:0048593	2	0.019
compound eye development	GO:0048749	307	0.019
negative regulation of terminal cell fate specification open tracheal system	GO:0035155	2	0.018
heart development	GO:0007507	82	0.018
regulation of cell cycle	GO:0051726	291	0.018	Human Mouse
morphogenesis of a branching epithelium	GO:0061138	45	0.018
regulation of molecular function	GO:0065009	217	0.018	Human Zebrafish Mouse
negative regulation of cyclin dependent protein serine threonine kinase activity	GO:0045736	1	0.018
negative regulation of developmental pigmentation	GO:0048086	1	0.018
negative regulation of signaling	GO:0023057	219	0.018
unsaturated fatty acid biosynthetic process	GO:0006636	1	0.018
dendrite regeneration	GO:0031104	2	0.018
cellular nitrogen compound catabolic process	GO:0044270	165	0.017
leg disc development	GO:0035218	92	0.017
centrosome organization	GO:0051297	163	0.017
regulation of protein localization to nucleus	GO:1900180	29	0.017	Human Mouse
regulation of cell cycle checkpoint	GO:1901976	2	0.017
negative regulation of canonical wnt signaling pathway	GO:0090090	6	0.017	Human Zebrafish Mouse
chromosome condensation	GO:0030261	41	0.017
spermatid differentiation	GO:0048515	114	0.017
negative regulation of molecular function	GO:0044092	51	0.016
regulation of nuclear division	GO:0051783	58	0.016
regulation of planar cell polarity pathway involved in axis elongation	GO:2000040	2	0.016
mitochondrial membrane organization	GO:0007006	3	0.016
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.016
nucleotide catabolic process	GO:0009166	109	0.016
response to abiotic stimulus	GO:0009628	341	0.016
positive regulation of phosphorylation	GO:0042327	87	0.016	Human Zebrafish Mouse
apoptotic process	GO:0006915	159	0.016
dna templated transcriptional start site selection	GO:0001173	1	0.016
cytoplasmic microtubule organization	GO:0031122	22	0.016	Mouse
negative regulation of g1 s transition of mitotic cell cycle	GO:2000134	13	0.015
segment polarity determination	GO:0007367	25	0.015
muscle cell differentiation	GO:0042692	103	0.015	Zebrafish
regulation of protein catabolic process	GO:0042176	55	0.015	Human Mouse
response to other organism	GO:0051707	293	0.014
ribonucleoside catabolic process	GO:0042454	112	0.014
developmental programmed cell death	GO:0010623	138	0.014
regulation of ruffle assembly	GO:1900027	1	0.014
r3 r4 cell fate commitment	GO:0007464	10	0.014
negative regulation of mitochondrial fusion	GO:0010637	2	0.014
periodic partitioning	GO:0007365	29	0.014
positive regulation of cellular catabolic process	GO:0031331	95	0.014	Mouse
photoreceptor cell fate commitment	GO:0046552	41	0.014
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.014	Mouse
organelle assembly	GO:0070925	198	0.014
positive regulation of growth	GO:0045927	75	0.014	Worm
specification of segmental identity antennal segment	GO:0007383	2	0.014
stem cell proliferation	GO:0072089	88	0.014
endocytosis	GO:0006897	310	0.014
regulation of developmental growth	GO:0048638	174	0.013	Worm
signal transduction in response to dna damage	GO:0042770	3	0.013
fertilization	GO:0009566	26	0.013
germarium derived egg chamber formation	GO:0007293	101	0.013
response to nitrogen compound	GO:1901698	90	0.013
regulation of atpase activity	GO:0043462	4	0.013
protein localization	GO:0008104	284	0.013	Human Mouse Worm
negative regulation of cellular biosynthetic process	GO:0031327	277	0.013	Mouse
negative regulation of sister chromatid cohesion	GO:0045875	1	0.013
regulation of reactive oxygen species biosynthetic process	GO:1903426	0	0.013
cell cycle phase transition	GO:0044770	140	0.013
negative regulation of dna templated transcription initiation	GO:2000143	1	0.013
circulatory system development	GO:0072359	82	0.013
purine nucleotide catabolic process	GO:0006195	109	0.013
negative regulation of pigment cell differentiation	GO:0050941	1	0.013
positive regulation of phosphate metabolic process	GO:0045937	139	0.012	Human Zebrafish Mouse
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.012
positive regulation of transcription involved in g2 m transition of mitotic cell cycle	GO:0090282	1	0.012
response to red light	GO:0010114	2	0.012
epithelial to mesenchymal transition	GO:0001837	1	0.012	Human
phosphorylation	GO:0016310	294	0.012	Human Zebrafish Mouse
rna interference	GO:0016246	27	0.012
non canonical wnt signaling pathway	GO:0035567	8	0.012
regulation of ran gtpase activity	GO:0032316	1	0.011
convergent extension	GO:0060026	2	0.011
regulation of symbiosis encompassing mutualism through parasitism	GO:0043903	15	0.011
regulation of compound eye pigmentation	GO:0048076	7	0.011
ribonucleotide catabolic process	GO:0009261	109	0.011
meiotic dna repair synthesis	GO:0000711	3	0.011
heterocycle catabolic process	GO:0046700	166	0.011
fatty acid derivative biosynthetic process	GO:1901570	1	0.011
regulation of cellular response to stress	GO:0080135	89	0.011	Human Zebrafish Mouse
regulation of nucleotide metabolic process	GO:0006140	62	0.011
hemocyte differentiation	GO:0042386	38	0.011
regulation of mrna processing	GO:0050684	71	0.011
epithelial cell development	GO:0002064	274	0.011
muscle system process	GO:0003012	21	0.011
dna templated transcription elongation	GO:0006354	18	0.011	Mouse
defense response to gram negative bacterium	GO:0050829	94	0.011
central nervous system development	GO:0007417	201	0.011	Zebrafish
compound eye morphogenesis	GO:0001745	249	0.011
immune response	GO:0006955	246	0.011
smoothened signaling pathway	GO:0007224	49	0.011
prostanoid biosynthetic process	GO:0046457	1	0.011
positive regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis	GO:2001272	4	0.011
regulation of immune system process	GO:0002682	176	0.011
positive regulation of mapk cascade	GO:0043410	63	0.011	Zebrafish Mouse
genitalia development	GO:0048806	26	0.010	Worm
stem cell differentiation	GO:0048863	117	0.010
positive regulation of nervous system development	GO:0051962	69	0.010
epithelial cell differentiation	GO:0030855	322	0.010
positive regulation of i kappab kinase nf kappab signaling	GO:0043123	1	0.010
regulation of presynaptic membrane organization	GO:1901629	1	0.010
regulation of cell division	GO:0051302	72	0.010
regulation of homotypic cell cell adhesion	GO:0034110	2	0.010
actin cytoskeleton organization	GO:0030036	206	0.010
regulation of protein targeting	GO:1903533	29	0.010	Human Mouse
cellular component assembly involved in morphogenesis	GO:0010927	151	0.010

Axn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of anatomical entity	DOID:7	0.092
musculoskeletal system disease	DOID:17	0.052
organ system cancer	DOID:0050686	0.035	Human
disease of cellular proliferation	DOID:14566	0.035	Human
cancer	DOID:162	0.035	Human
aortic valve disease	DOID:62	0.019
cardiovascular system disease	DOID:1287	0.019
heart disease	DOID:114	0.019
heart valve disease	DOID:4079	0.019
nervous system disease	DOID:863	0.019
thyroid cancer	DOID:1781	0.018
follicular thyroid carcinoma	DOID:3962	0.018
thyroid carcinoma	DOID:3963	0.018
endocrine gland cancer	DOID:170	0.018
aortic disease	DOID:520	0.011
vascular disease	DOID:178	0.011
artery disease	DOID:0050828	0.011

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