Drosophila melanogaster

95 known processes

Axn (Dmel_CG7926)

Axin

(Aliases: dAxin,dAXIN,axin,d-axin,0442/30,DAxin,din,D-Axin,Dmel\CG7926,Daxin,CG7926,axn,l(3)S044230)

Axn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
muscle structure developmentGO:00610612240.995
Zebrafish
regulation of transcription from rna polymerase ii promoterGO:00063573780.969
Mouse
transcription from rna polymerase ii promoterGO:00063663680.899
Mouse
nuclear divisionGO:00002803320.793
chromosome segregationGO:00070591570.784
Human Mouse
regulation of multicellular organismal developmentGO:20000264140.780
Human Mouse Worm
positive regulation of rna biosynthetic processGO:19026802660.770
Human Mouse
muscle organ developmentGO:00075171270.725
positive regulation of signal transductionGO:00099672230.713
Zebrafish Mouse
catabolic processGO:00090564090.711
Human Mouse
organelle fissionGO:00482853400.688
regulation of cell cycle phase transitionGO:19019871300.608
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.559
imaginal disc derived appendage developmentGO:00487373990.547
regulation of wnt signaling pathwayGO:0030111680.537
positive regulation of gene expressionGO:00106282900.512
Human Mouse
regulation of organ growthGO:0046620420.457
positive regulation of cellular biosynthetic processGO:00313283160.429
Human Mouse
meiotic cell cycleGO:00513211710.427
positive regulation of rna metabolic processGO:00512542710.375
Human Mouse
immune system processGO:00023763470.374
Mouse
imaginal disc derived wing margin morphogenesisGO:0008587410.372
positive regulation of macromolecule metabolic processGO:00106044050.351
Human Zebrafish Mouse
positive regulation of response to stimulusGO:00485843230.350
Zebrafish Mouse
sister chromatid segregationGO:0000819920.340
meiotic cell cycle processGO:19030461320.331
regulation of transportGO:00510491810.330
Human Mouse
covalent chromatin modificationGO:00165691060.320
regulation of anatomical structure morphogenesisGO:00226032420.319
Human
regulation of cell cycle processGO:00105641810.316
Human Mouse
positive regulation of stem cell differentiationGO:200073830.314
Human
positive regulation of macromolecule biosynthetic processGO:00105572830.304
Human Mouse
positive regulation of nitrogen compound metabolic processGO:00511733540.302
Human Mouse
tube developmentGO:00352952440.288
Mouse
imaginal disc growthGO:0007446370.288
regulation of mitotic cell cycleGO:00073461900.272
positive regulation of developmental processGO:00510941430.268
Human Worm
mitotic nuclear divisionGO:00070672130.266
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.250
Mouse
organ growthGO:0035265560.246
response to organic cyclic compoundGO:0014070890.213
meiotic nuclear divisionGO:00071261510.202
positive regulation of nucleic acid templated transcriptionGO:19035082660.192
Human Mouse
prostaglandin biosynthetic processGO:000151610.190
spindle organizationGO:00070512530.187
Worm
chromosome organizationGO:00512763600.174
Human Mouse
respiratory system developmentGO:00605412130.174
Zebrafish
mitotic cell cycle embryonicGO:0045448380.173
developmental growthGO:00485892800.170
Zebrafish Worm
macromolecule catabolic processGO:00090571610.168
Human Mouse
organic substance catabolic processGO:19015753080.168
Human Mouse
positive regulation of transcription dna templatedGO:00458932660.166
Human Mouse
regulation of protein import into nucleusGO:0042306280.163
Human Mouse
eye morphogenesisGO:00485922600.160
Zebrafish
digestive system developmentGO:00551231490.156
Mouse
positive regulation of protein import into nucleusGO:0042307210.154
mrna processingGO:00063971040.153
regulation of epithelial cell proliferationGO:005067840.146
mitotic spindle organizationGO:00070522200.134
Worm
post embryonic appendage morphogenesisGO:00351203850.132
regulation of intracellular protein transportGO:0033157460.127
Human Mouse
male gamete generationGO:00482322010.121
dorsal ventral pattern formationGO:00099531330.119
Zebrafish Mouse
axis specificationGO:00097981670.119
Zebrafish Mouse Worm
heart field specificationGO:000312800.119
Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459353320.117
Human Mouse
protein transportGO:00150311550.111
Human Mouse
proteolysisGO:00065081920.111
Mouse
positive regulation of signalingGO:00230562430.110
Zebrafish Mouse
histone modificationGO:00165701060.104
positive regulation of nucleocytoplasmic transportGO:0046824240.104
dna conformation changeGO:00711031050.103
protein localization to nucleusGO:0034504550.103
Human Mouse
multicellular organismal reproductive behaviorGO:00330571100.103
Worm
positive regulation of protein localization to nucleusGO:1900182210.102
regulation of multi organism processGO:00439001310.101
nuclear importGO:0051170510.100
Human Mouse
imaginal disc derived leg morphogenesisGO:0007480800.100
cell proliferationGO:00082832990.099
Human Mouse
reproductive behaviorGO:00190981220.097
Worm
eye developmentGO:00016543230.097
Zebrafish
leg disc morphogenesisGO:0007478800.097
appendage developmentGO:00487364010.097
dna metabolic processGO:00062592270.096
Human
positive regulation of multicellular organismal processGO:00512401430.096
Human Worm
mapk cascadeGO:00001651070.095
Zebrafish Mouse
negative regulation of cell cycle phase transitionGO:19019881030.091
meiosis iGO:0007127590.090
defense response to bacteriumGO:00427421780.086
spermatogenesisGO:00072832000.086
positive regulation of developmental growthGO:0048639620.086
Worm
gonad developmentGO:0008406500.086
Worm
mesenchymal cell differentiationGO:004876210.084
Human
wing disc morphogenesisGO:00074723440.082
phagocytosisGO:00069092150.080
positive regulation of cell developmentGO:0010720610.080
Human
body morphogenesisGO:001017120.080
positive regulation of protein transportGO:0051222370.075
multi multicellular organism processGO:00447061230.074
Worm
cellular protein localizationGO:00346131600.073
Human Mouse
muscle tissue developmentGO:0060537300.072
protein localization to organelleGO:0033365820.071
Human Mouse
response to biotic stimulusGO:00096072940.071
homeostatic processGO:00425921990.071
Mouse
asymmetric cell divisionGO:0008356370.070
regulation of localizationGO:00328792750.069
Human Mouse Worm
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.069
chromatin modificationGO:00165681470.068
regulation of cell differentiationGO:00455953020.067
organophosphate metabolic processGO:00196371950.065
nucleoside metabolic processGO:00091161270.063
cell divisionGO:00513012480.061
regulation of organ morphogenesisGO:2000027780.061
positive regulation of biosynthetic processGO:00098913160.059
Human Mouse
open tracheal system developmentGO:00074242040.058
negative regulation of epithelial cell proliferationGO:005068040.058
protein import into nucleusGO:0006606510.057
Human Mouse
establishment of protein localization to organelleGO:0072594620.056
Human Mouse
sex differentiationGO:0007548810.055
Worm
protein targetingGO:0006605640.055
Human Mouse
cell motilityGO:00488702510.055
Worm
organic cyclic compound catabolic processGO:19013611680.055
regulation of imaginal disc growthGO:0045570260.055
positive regulation of intracellular protein transportGO:0090316300.054
positive regulation of transportGO:0051050920.054
wnt signaling pathwayGO:0016055980.054
retina development in camera type eyeGO:006004140.054
regulation of protein transportGO:0051223570.054
Human Mouse
single organism biosynthetic processGO:00447112060.054
dna packagingGO:0006323910.053
positive regulation of wnt signaling pathwayGO:0030177250.053
negative regulation of wnt signaling pathwayGO:0030178280.053
mitotic cytokinesisGO:0000281500.053
regulation of phosphorus metabolic processGO:00511742100.051
Human Zebrafish Mouse
regulation of protein localizationGO:0032880760.051
Human Mouse Worm
dna integrationGO:001507410.051
embryo development ending in birth or egg hatchingGO:00097921520.051
Zebrafish Mouse
establishment of localization in cellGO:00516494020.050
Human Mouse
macromolecular complex assemblyGO:00650032560.049
Human Mouse
regulation of nucleocytoplasmic transportGO:0046822350.049
Human Mouse
axon guidanceGO:00074112330.048
Worm
imaginal disc derived wing vein morphogenesisGO:0008586440.047
reproductive structure developmentGO:0048608740.046
Worm
negative regulation of cell cycle processGO:00109481090.046
cellular catabolic processGO:00442483720.046
Mouse
oocyte morphogenesisGO:004860130.045
chromatin organizationGO:00063252070.045
regulation of establishment of protein localizationGO:0070201610.044
Human Mouse
negative regulation of programmed cell deathGO:0043069720.044
regulation of dna metabolic processGO:0051052340.044
Human
blastoderm segmentationGO:00073501590.044
single organism nuclear importGO:1902593510.043
Human Mouse
regulation of intracellular signal transductionGO:19025312360.042
Zebrafish Mouse
instar larval developmentGO:0002168550.042
response to external biotic stimulusGO:00432072930.042
canonical wnt signaling pathway involved in heart developmentGO:006131630.042
memoryGO:0007613940.042
regulation of cellular localizationGO:00603411360.041
Human Mouse
dorsal ventral axis specificationGO:0009950660.041
Zebrafish Mouse
neuron projection guidanceGO:00974852410.040
Worm
endodermal cell fate commitmentGO:000171130.039
growthGO:00400073590.039
Zebrafish Worm
intracellular protein transportGO:00068861040.039
Human Mouse
stem cell maintenanceGO:0019827670.039
negative regulation of multicellular organismal processGO:00512411420.038
Mouse Worm
nucleobase containing small molecule metabolic processGO:00550861740.038
imaginal disc derived appendage morphogenesisGO:00351143950.038
tracheal outgrowth open tracheal systemGO:0007426180.036
negative regulation of macromolecule biosynthetic processGO:00105582700.036
Mouse
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.036
positive regulation of intracellular signal transductionGO:19025331160.036
Zebrafish Mouse
appendage morphogenesisGO:00351073970.034
brain developmentGO:00074201200.034
Zebrafish
negative regulation of nucleic acid templated transcriptionGO:19035072400.034
Mouse
regulation of cell developmentGO:00602842150.034
Human Mouse
cellular response to organic substanceGO:00713101320.034
Mouse
developmental growth involved in morphogenesisGO:0060560650.034
response to oxygen containing compoundGO:19017002000.033
multi organism reproductive behaviorGO:00447051210.032
Worm
organonitrogen compound metabolic processGO:19015643180.032
cytokinesisGO:0000910900.032
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encodedGO:000807110.032
carbohydrate derivative metabolic processGO:19011352170.032
imaginal disc derived wing morphogenesisGO:00074763370.032
epithelial cell fate determination open tracheal systemGO:000742520.031
positive regulation of cellular component organizationGO:00511301560.031
Human
cellular macromolecule localizationGO:00707272200.031
Human Mouse
mrna metabolic processGO:00160711240.031
response to organic substanceGO:00100332840.031
Mouse
molting cycleGO:0042303560.031
organelle localizationGO:00516401480.031
small molecule metabolic processGO:00442813050.031
regulation of chromosome organizationGO:0033044640.031
Human Mouse
vesicle mediated transportGO:00161923810.030
regulation of mapk cascadeGO:0043408920.030
Zebrafish Mouse
endodermal cell differentiationGO:003598730.030
nucleoside triphosphate metabolic processGO:00091411200.030
regulation of cellular protein metabolic processGO:00322682430.029
Human Zebrafish Mouse
regulation of cytoplasmic transportGO:1903649470.028
Human Mouse
negative regulation of cell communicationGO:00106482230.028
wnt signaling pathway involved in heart developmentGO:000330630.028
hindbrain developmentGO:003090220.027
antimicrobial humoral responseGO:0019730990.027
negative regulation of mitotic cell cycleGO:00459301090.027
cellular response to chemical stimulusGO:00708871990.026
Mouse
dna recombinationGO:0006310320.026
cellular response to oxygen containing compoundGO:1901701790.026
establishment of protein localizationGO:00451841630.026
Human Mouse
protein catabolic processGO:00301631010.026
Human Mouse
single organism cellular localizationGO:19025801800.025
Human Mouse
aromatic compound catabolic processGO:00194391660.025
protein complex assemblyGO:00064612000.025
Human Mouse
regulation of cell proliferation involved in compound eye morphogenesisGO:200049520.025
positive regulation of intracellular transportGO:0032388420.024
protein targeting to nucleusGO:0044744510.024
Human Mouse
segmentationGO:00352822070.024
Zebrafish Mouse
mitotic cell cycle phase transitionGO:00447721380.024
mitotic sister chromatid segregationGO:0000070870.024
multi organism behaviorGO:00517051750.024
Worm
positive regulation of chromatin silencing at telomereGO:003194020.024
renal system developmentGO:0072001720.024
positive regulation of multi organism processGO:0043902400.024
nuclear migrationGO:0007097200.023
response to alcoholGO:0097305950.023
protein modification processGO:00362114380.023
Human Zebrafish Mouse
oocyte fate commitmentGO:004860020.023
regulation of phosphate metabolic processGO:00192202100.022
Human Zebrafish Mouse
anatomical structure homeostasisGO:0060249970.022
single organism carbohydrate metabolic processGO:0044723720.022
meiotic spindle checkpointGO:004477910.022
positive regulation of organelle organizationGO:0010638650.022
positive regulation of cell communicationGO:00106472500.022
Zebrafish Mouse
cell deathGO:00082192790.022
Human
spinal cord developmentGO:002151010.021
humoral immune responseGO:00069591170.021
maintenance of gastrointestinal epitheliumGO:003027730.021
cellular response to organic cyclic compoundGO:0071407320.021
detection of virusGO:000959710.021
regulation of i kappab kinase nf kappab signalingGO:004312220.021
icosanoid biosynthetic processGO:004645610.021
regulation of protein metabolic processGO:00512462560.021
Human Zebrafish Mouse
protein complex biogenesisGO:00702712010.021
Human Mouse
positive regulation of catabolic processGO:00098961050.020
Human Mouse
negative regulation of cell cycleGO:00457861160.020
regulation of dna templated transcription elongationGO:0032784170.020
Mouse
meiotic nuclear envelope disassemblyGO:005107820.020
deathGO:00162652840.020
Human
juvenile hormone mediated signaling pathwayGO:003562630.020
regulation of mitotic cell cycle phase transitionGO:19019901300.020
neuroblast proliferationGO:0007405740.020
organophosphate catabolic processGO:00464341120.020
male meiosisGO:0007140520.020
single organism catabolic processGO:00447122280.020
digestive tract morphogenesisGO:00485461270.020
Mouse
compound eye photoreceptor fate commitmentGO:0001752360.020
regulation of catabolic processGO:00098941700.019
Human Mouse
defense response to other organismGO:00985422250.019
protein modification by small protein conjugation or removalGO:00706471060.019
Human Mouse
signal transduction by phosphorylationGO:00230141070.019
Zebrafish Mouse
macromolecule methylationGO:0043414450.019
carbohydrate derivative catabolic processGO:19011361180.019
intrinsic apoptotic signaling pathwayGO:0097193160.019
camera type eye morphogenesisGO:004859320.019
compound eye developmentGO:00487493070.019
negative regulation of terminal cell fate specification open tracheal systemGO:003515520.018
heart developmentGO:0007507820.018
regulation of cell cycleGO:00517262910.018
Human Mouse
morphogenesis of a branching epitheliumGO:0061138450.018
regulation of molecular functionGO:00650092170.018
Human Zebrafish Mouse
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573610.018
negative regulation of developmental pigmentationGO:004808610.018
negative regulation of signalingGO:00230572190.018
unsaturated fatty acid biosynthetic processGO:000663610.018
dendrite regenerationGO:003110420.018
cellular nitrogen compound catabolic processGO:00442701650.017
leg disc developmentGO:0035218920.017
centrosome organizationGO:00512971630.017
regulation of protein localization to nucleusGO:1900180290.017
Human Mouse
regulation of cell cycle checkpointGO:190197620.017
negative regulation of canonical wnt signaling pathwayGO:009009060.017
Human Zebrafish Mouse
chromosome condensationGO:0030261410.017
spermatid differentiationGO:00485151140.017
negative regulation of molecular functionGO:0044092510.016
regulation of nuclear divisionGO:0051783580.016
regulation of planar cell polarity pathway involved in axis elongationGO:200004020.016
mitochondrial membrane organizationGO:000700630.016
negative regulation of mitotic cell cycle phase transitionGO:19019911030.016
nucleotide catabolic processGO:00091661090.016
response to abiotic stimulusGO:00096283410.016
positive regulation of phosphorylationGO:0042327870.016
Human Zebrafish Mouse
apoptotic processGO:00069151590.016
dna templated transcriptional start site selectionGO:000117310.016
cytoplasmic microtubule organizationGO:0031122220.016
Mouse
negative regulation of g1 s transition of mitotic cell cycleGO:2000134130.015
segment polarity determinationGO:0007367250.015
muscle cell differentiationGO:00426921030.015
Zebrafish
regulation of protein catabolic processGO:0042176550.015
Human Mouse
response to other organismGO:00517072930.014
ribonucleoside catabolic processGO:00424541120.014
developmental programmed cell deathGO:00106231380.014
regulation of ruffle assemblyGO:190002710.014
r3 r4 cell fate commitmentGO:0007464100.014
negative regulation of mitochondrial fusionGO:001063720.014
periodic partitioningGO:0007365290.014
positive regulation of cellular catabolic processGO:0031331950.014
Mouse
photoreceptor cell fate commitmentGO:0046552410.014
negative regulation of nucleobase containing compound metabolic processGO:00459342610.014
Mouse
organelle assemblyGO:00709251980.014
positive regulation of growthGO:0045927750.014
Worm
specification of segmental identity antennal segmentGO:000738320.014
stem cell proliferationGO:0072089880.014
endocytosisGO:00068973100.014
regulation of developmental growthGO:00486381740.013
Worm
signal transduction in response to dna damageGO:004277030.013
fertilizationGO:0009566260.013
germarium derived egg chamber formationGO:00072931010.013
response to nitrogen compoundGO:1901698900.013
regulation of atpase activityGO:004346240.013
protein localizationGO:00081042840.013
Human Mouse Worm
negative regulation of cellular biosynthetic processGO:00313272770.013
Mouse
negative regulation of sister chromatid cohesionGO:004587510.013
regulation of reactive oxygen species biosynthetic processGO:190342600.013
cell cycle phase transitionGO:00447701400.013
negative regulation of dna templated transcription initiationGO:200014310.013
circulatory system developmentGO:0072359820.013
purine nucleotide catabolic processGO:00061951090.013
negative regulation of pigment cell differentiationGO:005094110.013
positive regulation of phosphate metabolic processGO:00459371390.012
Human Zebrafish Mouse
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.012
positive regulation of transcription involved in g2 m transition of mitotic cell cycleGO:009028210.012
response to red lightGO:001011420.012
epithelial to mesenchymal transitionGO:000183710.012
Human
phosphorylationGO:00163102940.012
Human Zebrafish Mouse
rna interferenceGO:0016246270.012
non canonical wnt signaling pathwayGO:003556780.012
regulation of ran gtpase activityGO:003231610.011
convergent extensionGO:006002620.011
regulation of symbiosis encompassing mutualism through parasitismGO:0043903150.011
regulation of compound eye pigmentationGO:004807670.011
ribonucleotide catabolic processGO:00092611090.011
meiotic dna repair synthesisGO:000071130.011
heterocycle catabolic processGO:00467001660.011
fatty acid derivative biosynthetic processGO:190157010.011
regulation of cellular response to stressGO:0080135890.011
Human Zebrafish Mouse
regulation of nucleotide metabolic processGO:0006140620.011
hemocyte differentiationGO:0042386380.011
regulation of mrna processingGO:0050684710.011
epithelial cell developmentGO:00020642740.011
muscle system processGO:0003012210.011
dna templated transcription elongationGO:0006354180.011
Mouse
defense response to gram negative bacteriumGO:0050829940.011
central nervous system developmentGO:00074172010.011
Zebrafish
compound eye morphogenesisGO:00017452490.011
immune responseGO:00069552460.011
smoothened signaling pathwayGO:0007224490.011
prostanoid biosynthetic processGO:004645710.011
positive regulation of cysteine type endopeptidase activity involved in execution phase of apoptosisGO:200127240.011
regulation of immune system processGO:00026821760.011
positive regulation of mapk cascadeGO:0043410630.011
Zebrafish Mouse
genitalia developmentGO:0048806260.010
Worm
stem cell differentiationGO:00488631170.010
positive regulation of nervous system developmentGO:0051962690.010
epithelial cell differentiationGO:00308553220.010
positive regulation of i kappab kinase nf kappab signalingGO:004312310.010
regulation of presynaptic membrane organizationGO:190162910.010
regulation of cell divisionGO:0051302720.010
regulation of homotypic cell cell adhesionGO:003411020.010
actin cytoskeleton organizationGO:00300362060.010
regulation of protein targetingGO:1903533290.010
Human Mouse
cellular component assembly involved in morphogenesisGO:00109271510.010

Axn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.092
musculoskeletal system diseaseDOID:1700.052
organ system cancerDOID:005068600.035
Human
disease of cellular proliferationDOID:1456600.035
Human
cancerDOID:16200.035
Human
aortic valve diseaseDOID:6200.019
cardiovascular system diseaseDOID:128700.019
heart diseaseDOID:11400.019
heart valve diseaseDOID:407900.019
nervous system diseaseDOID:86300.019
thyroid cancerDOID:178100.018
follicular thyroid carcinomaDOID:396200.018
thyroid carcinomaDOID:396300.018
endocrine gland cancerDOID:17000.018
aortic diseaseDOID:52000.011
vascular diseaseDOID:17800.011
artery diseaseDOID:005082800.011