Drosophila melanogaster

55 known processes

SRPK (Dmel_CG8174)

CG8174 gene product from transcript CG8174-RA

(Aliases: BcDNA:SD03158,dSRPK1,CG8174,dSRPK,srpk,Dmel\CG8174)

SRPK biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oocyte developmentGO:00485991240.991
oocyte differentiationGO:00099941450.985
oocyte axis specificationGO:00073091080.977
pole plasm assemblyGO:0007315610.964
oocyte constructionGO:00073081120.931
pole plasm mrna localizationGO:0019094490.882
germarium derived egg chamber formationGO:00072931010.856
cytoplasm organizationGO:0007028640.811
negative regulation of biosynthetic processGO:00098902770.797
pole plasm rna localizationGO:0007316520.779
germarium derived oocyte differentiationGO:0030706290.635
oocyte anterior posterior axis specificationGO:0007314720.633
oocyte microtubule cytoskeleton organizationGO:0016325350.620
organelle assemblyGO:00709251980.607
negative regulation of cellular biosynthetic processGO:00313272770.551
pole plasm oskar mrna localizationGO:0045451460.548
axis specificationGO:00097981670.516
establishment of localization in cellGO:00516494020.498
organelle localizationGO:00516401480.477
negative regulation of macromolecule biosynthetic processGO:00105582700.454
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.446
germarium derived oocyte fate determinationGO:0007294260.432
karyosome formationGO:0030717220.399
regulation of rna splicingGO:0043484690.399
regulation of pole plasm oskar mrna localizationGO:0007317270.388
negative regulation of cellular metabolic processGO:00313243820.386
organelle fissionGO:00482853400.383
rna splicingGO:0008380830.377
Human Mouse
negative regulation of nitrogen compound metabolic processGO:00511722650.371
columnar cuboidal epithelial cell differentiationGO:00020652560.354
mitotic nuclear divisionGO:00070672130.317
negative regulation of gene expressionGO:00106293870.317
dorsal ventral axis specificationGO:0009950660.298
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.288
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.277
columnar cuboidal epithelial cell developmentGO:00020662490.262
oocyte dorsal ventral axis specificationGO:0007310340.244
regulation of growthGO:00400082330.227
cell divisionGO:00513012480.222
Zebrafish Worm
developmental maturationGO:00217001720.205
negative regulation of nucleobase containing compound metabolic processGO:00459342610.205
intracellular mrna localizationGO:0008298660.200
establishment of organelle localizationGO:00516561220.197
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.196
anterior posterior axis specification embryoGO:00085951030.191
mitotic spindle organizationGO:00070522200.189
ovarian follicle cell developmentGO:00307072480.188
spindle organizationGO:00070512530.187
defense responseGO:00069523000.172
regulation of reproductive processGO:2000241540.168
rna localizationGO:00064031150.166
single organism cellular localizationGO:19025801800.164
chromosome organizationGO:00512763600.158
negative regulation of rna biosynthetic processGO:19026792400.154
growthGO:00400073590.148
deathGO:00162652840.144
Mouse Worm
macromolecular complex assemblyGO:00650032560.137
mrna processingGO:00063971040.133
Human Mouse
negative regulation of nucleic acid templated transcriptionGO:19035072400.132
intracellular transportGO:00469072280.129
transcription from rna polymerase ii promoterGO:00063663680.129
mrna metabolic processGO:00160711240.129
Human Mouse
dorsal ventral pattern formationGO:00099531330.124
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.123
Human Mouse
mrna splicing via spliceosomeGO:0000398730.120
Human Mouse
maternal determination of anterior posterior axis embryoGO:0008358740.119
regulation of oocyte developmentGO:0060281270.117
anterior posterior pattern specificationGO:00099521360.115
Zebrafish
anterior posterior axis specificationGO:00099481090.114
regulation of mrna splicing via spliceosomeGO:0048024640.113
meiotic cell cycle processGO:19030461320.113
cell maturationGO:00484691440.105
regulation of alternative mrna splicing via spliceosomeGO:0000381600.105
negative regulation of transcription dna templatedGO:00458922370.105
developmental growthGO:00485892800.104
oocyte fate determinationGO:0030716270.101
tripartite regional subdivisionGO:00073511030.100
rna processingGO:00063961470.100
Human Mouse
defense response to other organismGO:00985422250.098
regulation of protein metabolic processGO:00512462560.096
cellular macromolecule localizationGO:00707272200.092
alternative mrna splicing via spliceosomeGO:0000380600.090
single organism intracellular transportGO:19025822070.088
single organism biosynthetic processGO:00447112060.087
positive regulation of cellular biosynthetic processGO:00313283160.085
oocyte localization involved in germarium derived egg chamber formationGO:0030720120.084
positive regulation of rna metabolic processGO:00512542710.082
gene silencing by rnaGO:0031047570.082
segmentationGO:00352822070.077
Zebrafish
embryonic pattern specificationGO:00098801740.077
neurological system processGO:00508773580.073
regulation of cell differentiationGO:00455953020.073
rna splicing via transesterification reactionsGO:0000375730.072
Human Mouse
intracellular mrna localization involved in pattern specification processGO:0060810560.072
epithelial cell differentiationGO:00308553220.069
cell deathGO:00082192790.067
Mouse Worm
response to biotic stimulusGO:00096072940.066
protein localizationGO:00081042840.066
enzyme linked receptor protein signaling pathwayGO:00071671790.064
regulation of cell developmentGO:00602842150.063
meiotic spindle organizationGO:0000212360.063
regionalizationGO:00030024160.060
Zebrafish
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.057
cell proliferationGO:00082832990.057
Human Mouse
rna catabolic processGO:0006401370.056
organic substance catabolic processGO:19015753080.054
embryonic axis specificationGO:00005781070.054
regulation of response to stressGO:00801342000.054
neuron projection guidanceGO:00974852410.054
positive regulation of macromolecule biosynthetic processGO:00105572830.053
dna metabolic processGO:00062592270.052
cellular response to dna damage stimulusGO:00069742230.051
endocytosisGO:00068973100.051
cytoskeleton dependent cytokinesisGO:0061640810.051
positive regulation of nucleic acid templated transcriptionGO:19035082660.051
ribonucleoprotein complex subunit organizationGO:0071826280.050
Human Mouse
regulation of multicellular organismal developmentGO:20000264140.050
establishment of spindle localizationGO:0051293220.050
rrna processingGO:000636430.048
cellular response to chemical stimulusGO:00708871990.048
negative regulation of cellular protein metabolic processGO:0032269850.048
translationGO:0006412690.048
posttranscriptional regulation of gene expressionGO:00106081450.046
Zebrafish
cellular macromolecule catabolic processGO:00442651360.046
regulation of cellular amine metabolic processGO:003323830.045
regulation of nervous system developmentGO:00519602480.044
protein ubiquitinationGO:0016567700.044
establishment or maintenance of cell polarityGO:00071631670.044
regulation of localizationGO:00328792750.044
cellular macromolecular complex assemblyGO:00346221530.043
Human Mouse
chromosome segregationGO:00070591570.043
Human
regulation of translationGO:0006417560.042
mrna catabolic processGO:0006402330.041
negative regulation of response to stimulusGO:00485852580.040
axon developmentGO:00615642970.040
spermatogenesisGO:00072832000.040
protein complex biogenesisGO:00702712010.040
regulation of transportGO:00510491810.040
regulation of nurse cell apoptotic processGO:004547790.039
organic substance transportGO:00717022570.039
regulation of cell cycle phase transitionGO:19019871300.039
body morphogenesisGO:001017120.038
nucleus localizationGO:0051647340.037
spindle assembly involved in mitosisGO:0090307500.037
homeostatic processGO:00425921990.037
response to bacteriumGO:00096171980.037
cellular protein modification processGO:00064644380.036
Human Zebrafish Mouse Worm
regulation of embryonic pattern specificationGO:1902875270.035
regulation of transcription from rna polymerase ii promoterGO:00063573780.035
chorion containing eggshell formationGO:00073041050.034
cell growthGO:00160491080.034
blastoderm segmentationGO:00073501590.034
dephosphorylationGO:0016311510.033
regulation of microtubule polymerization or depolymerizationGO:0031110270.033
immune responseGO:00069552460.033
head developmentGO:00603221350.033
negative regulation of rna metabolic processGO:00512532510.033
extracellular structure organizationGO:0043062460.033
regulation of cell maturationGO:1903429270.033
spindle localizationGO:0051653220.032
reproductive structure developmentGO:0048608740.032
Worm
regulation of microtubule based processGO:0032886490.032
negative regulation of translationGO:0017148280.032
cellular protein complex assemblyGO:0043623710.032
negative regulation of protein metabolic processGO:0051248850.032
regulation of cell cycle processGO:00105641810.031
morphogenesis of follicular epitheliumGO:0016333360.030
mitotic cell cycle phase transitionGO:00447721380.030
regulation of mrna metabolic processGO:1903311720.029
Human Mouse
negative regulation of cell cycle processGO:00109481090.029
nuclear divisionGO:00002803320.029
regulation of cellular ketone metabolic processGO:001056530.029
regulation of mrna processingGO:0050684710.029
Human Mouse
nitrogen compound transportGO:0071705850.028
response to abiotic stimulusGO:00096283410.028
actin cytoskeleton organizationGO:00300362060.028
appendage developmentGO:00487364010.028
stem cell differentiationGO:00488631170.028
positive regulation of nitrogen compound metabolic processGO:00511733540.028
negative regulation of nervous system developmentGO:0051961920.027
regulation of cellular protein metabolic processGO:00322682430.027
positive regulation of cellular component organizationGO:00511301560.027
negative regulation of phosphorus metabolic processGO:0010563450.027
ovarian fusome organizationGO:0030723110.027
positive regulation of macromolecule metabolic processGO:00106044050.027
Mouse
response to external biotic stimulusGO:00432072930.027
mesenchymal cell differentiationGO:004876210.027
negative regulation of signal transductionGO:00099682060.027
epithelial cell developmentGO:00020642740.027
regulation of cellular component biogenesisGO:00440872010.026
eggshell formationGO:00307031050.026
mesenchymal cell developmentGO:001403110.026
central nervous system developmentGO:00074172010.025
positive regulation of multicellular organismal processGO:00512401430.024
stem cell maintenanceGO:0019827670.024
establishment of cell polarityGO:0030010400.024
negative regulation of cell cycleGO:00457861160.023
Worm
eye morphogenesisGO:00485922600.023
eggshell chorion assemblyGO:0007306660.023
cellular component assembly involved in morphogenesisGO:00109271510.023
response to other organismGO:00517072930.023
vesicle mediated transportGO:00161923810.023
positive regulation of transcription dna templatedGO:00458932660.023
mrna transportGO:0051028150.023
negative regulation of developmental processGO:00510932010.023
regulation of cell cycleGO:00517262910.023
Mouse Worm
protein complex assemblyGO:00064612000.023
carboxylic acid metabolic processGO:0019752920.022
endomembrane system organizationGO:00102561190.022
negative regulation of cell communicationGO:00106482230.022
macromolecule catabolic processGO:00090571610.022
epidermal growth factor receptor signaling pathwayGO:0007173580.021
microtubule polymerization or depolymerizationGO:0031109390.021
ion transportGO:00068111450.021
positive regulation of response to stimulusGO:00485843230.021
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.021
cellular response to organic substanceGO:00713101320.021
meiosis iGO:0007127590.021
embryo development ending in birth or egg hatchingGO:00097921520.021
Zebrafish Worm
cytokinesisGO:0000910900.021
Worm
localization of cellGO:00516742570.020
cellular component disassemblyGO:0022411460.020
imaginal disc derived appendage developmentGO:00487373990.020
cellularizationGO:0007349900.020
organic cyclic compound catabolic processGO:19013611680.019
establishment of nucleus localizationGO:0040023260.019
synaptic vesicle localizationGO:0097479530.019
establishment or maintenance of cytoskeleton polarityGO:0030952440.019
posttranscriptional gene silencing by rnaGO:0035194450.019
negative regulation of smoothened signaling pathwayGO:0045879160.019
spinal cord developmentGO:002151010.019
pronuclear migrationGO:003504640.018
protein dna complex assemblyGO:0065004630.018
regulation of developmental growthGO:00486381740.018
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.018
vesicle organizationGO:0016050440.018
amine metabolic processGO:0009308120.017
negative regulation of protein complex disassemblyGO:0043242230.017
axon guidanceGO:00074112330.017
regulation of mitotic cell cycleGO:00073461900.017
Worm
microtubule cytoskeleton organization involved in mitosisGO:1902850520.016
genitalia developmentGO:0048806260.016
Worm
positive regulation of gene expressionGO:00106282900.016
Mouse
innate immune responseGO:00450871440.016
nuclear migrationGO:0007097200.016
positive regulation of rna biosynthetic processGO:19026802660.016
mitotic g2 dna damage checkpointGO:0007095690.016
negative regulation of cell differentiationGO:00455961430.016
response to nutrient levelsGO:00316671140.016
male gamete generationGO:00482322010.016
negative regulation of cell proliferationGO:0008285690.016
protein modification by small protein conjugationGO:0032446790.016
meiotic cell cycleGO:00513211710.016
negative regulation of cellular component organizationGO:00511291080.016
mitotic dna integrity checkpointGO:0044774750.016
defense response to bacteriumGO:00427421780.015
smoothened signaling pathwayGO:0007224490.015
proteolysisGO:00065081920.015
nucleocytoplasmic transportGO:0006913720.015
regulation of protein complex assemblyGO:0043254420.015
cellular nitrogen compound catabolic processGO:00442701650.015
compound eye morphogenesisGO:00017452490.015
lipid metabolic processGO:00066291210.014
stem cell developmentGO:0048864790.014
macromolecular complex disassemblyGO:0032984370.014
mitotic cytokinesisGO:0000281500.014
protein modification processGO:00362114380.014
Human Zebrafish Mouse Worm
cell fate determinationGO:0001709910.014
single organism behaviorGO:00447083910.014
rna transportGO:0050658460.014
oxoacid metabolic processGO:00434361030.014
negative regulation of cell deathGO:0060548810.014
oxidation reduction processGO:00551141230.014
reproductive system developmentGO:0061458740.014
Worm
mapk cascadeGO:00001651070.014
Zebrafish
microtubule organizing center organizationGO:00310231680.014
germ line cyst formationGO:0048134440.014
cell migrationGO:00164772380.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.014
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.013
negative regulation of signalingGO:00230572190.013
ncrna metabolic processGO:0034660430.013
nuclear transportGO:0051169720.013
regulation of cellular amino acid metabolic processGO:000652100.013
eye developmentGO:00016543230.013
modification dependent macromolecule catabolic processGO:0043632790.013
cell motilityGO:00488702510.013
cellular catabolic processGO:00442483720.013
cellular ketone metabolic processGO:0042180240.013
synaptic vesicle transportGO:0048489500.013
positive regulation of cellular amine metabolic processGO:003324000.012
protein transportGO:00150311550.012
negative regulation of microtubule depolymerizationGO:0007026210.012
intercellular bridge organizationGO:0043063140.012
establishment of mitotic spindle localizationGO:0040001170.012
regulation of multi organism processGO:00439001310.012
Human
cellular amino acid metabolic processGO:0006520610.012
regulation of cell deathGO:00109411730.012
Mouse
negative regulation of protein modification processGO:0031400290.012
axonogenesisGO:00074092900.012
dsrna fragmentationGO:0031050150.012
synaptic vesicle recyclingGO:0036465280.012
organic acid metabolic processGO:00060821030.012
immune system processGO:00023763470.012
response to organonitrogen compoundGO:0010243750.011
negative regulation of organelle organizationGO:0010639560.011
defense response to gram negative bacteriumGO:0050829940.011
developmental cell growthGO:0048588520.011
regulation of cellular response to stressGO:0080135890.011
cellular lipid metabolic processGO:0044255830.011
negative regulation of apoptotic processGO:0043066630.011
establishment of protein localizationGO:00451841630.011
erbb signaling pathwayGO:0038127580.011
cell cycle phase transitionGO:00447701400.011
nucleobase containing compound transportGO:0015931560.011
response to organic cyclic compoundGO:0014070890.011
mitotic dna damage checkpointGO:0044773740.011
cytoplasmic transportGO:00164821300.011
rhythmic processGO:00485111060.011
sensory organ morphogenesisGO:00905962600.011
positive regulation of signal transductionGO:00099672230.011
nuclear transcribed mrna catabolic processGO:0000956240.010
regulation of system processGO:0044057360.010
immune response regulating signaling pathwayGO:000276420.010
carbohydrate biosynthetic processGO:0016051170.010
regulation of organelle organizationGO:00330431960.010
positive regulation of nucleobase containing compound metabolic processGO:00459353320.010
neural precursor cell proliferationGO:0061351750.010
meiotic nuclear divisionGO:00071261510.010
fusome organizationGO:0045478130.010
oocyte microtubule cytoskeleton polarizationGO:0008103220.010
negative regulation of cell cycle phase transitionGO:19019881030.010

SRPK disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.118
musculoskeletal system diseaseDOID:1700.035
muscle tissue diseaseDOID:6600.032
muscular diseaseDOID:008000000.032
disease of cellular proliferationDOID:1456600.026
cancerDOID:16200.026
nervous system diseaseDOID:86300.021
neurodegenerative diseaseDOID:128900.017
central nervous system diseaseDOID:33100.017
cardiovascular system diseaseDOID:128700.014
organ system cancerDOID:005068600.013