Drosophila melanogaster

312 known processes

Lis-1 (Dmel_CG8440)

Lissencephaly-1

(Aliases: CG8440,Lis 1,Dlis-1,l(2R)W8,lis-1,dLis1,LIS-1,DLIS-1,DLIS1,D-Lis1,l(2)k13209,DLis1,Dmel\CG8440,DLis-1,Dlis1,lis1,Lis1,DmLIS1,n(2)k11702)

Lis-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
border follicle cell migrationGO:00072981131.000
epithelial cell migrationGO:00106311481.000
ovarian follicle cell migrationGO:00072971211.000
epithelium migrationGO:00901321481.000
ovarian follicle cell developmentGO:00307072481.000
oocyte microtubule cytoskeleton organizationGO:0016325350.998
cell migrationGO:00164772380.997
pronuclear migrationGO:003504640.997
Worm
ovarian fusome organizationGO:0030723110.996
cell motilityGO:00488702510.995
ameboidal type cell migrationGO:00016671510.993
localization of cellGO:00516742570.992
axonogenesisGO:00074092900.991
germarium derived oocyte fate determinationGO:0007294260.991
organelle localizationGO:00516401480.990
germarium derived oocyte differentiationGO:0030706290.989
eye developmentGO:00016543230.987
columnar cuboidal epithelial cell differentiationGO:00020652560.986
cell divisionGO:00513012480.986
immune system processGO:00023763470.985
Mouse
nucleus localizationGO:0051647340.983
single organism cellular localizationGO:19025801800.982
oocyte constructionGO:00073081120.981
epithelial cell differentiationGO:00308553220.980
developmental maturationGO:00217001720.976
oocyte axis specificationGO:00073091080.974
meiotic nuclear divisionGO:00071261510.972
Worm
developmental growthGO:00485892800.971
Rat
anterior posterior pattern specificationGO:00099521360.969
germarium derived egg chamber formationGO:00072931010.967
segmentationGO:00352822070.963
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.961
actin cytoskeleton organizationGO:00300362060.954
Mouse
cytokinesisGO:0000910900.949
regulation of neuron differentiationGO:00456641030.948
establishment or maintenance of cytoskeleton polarityGO:0030952440.948
pole plasm mrna localizationGO:0019094490.946
columnar cuboidal epithelial cell developmentGO:00020662490.937
oocyte anterior posterior axis specificationGO:0007314720.924
regulation of cell differentiationGO:00455953020.924
cytoskeleton dependent cytokinesisGO:0061640810.923
regulation of cell projection organizationGO:0031344920.920
regulation of cell developmentGO:00602842150.920
regulation of dendrite morphogenesisGO:0048814280.919
spermatogenesisGO:00072832000.918
taxisGO:00423303040.912
chemotaxisGO:00069352490.911
photoreceptor cell differentiationGO:00465301700.910
mitotic nuclear divisionGO:00070672130.906
Worm
intracellular signal transductionGO:00355563000.897
Mouse
epithelial cell developmentGO:00020642740.889
axon guidanceGO:00074112330.887
oocyte developmentGO:00485991240.885
fertilizationGO:0009566260.885
Worm
cellular protein modification processGO:00064644380.884
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.879
regulation of dendrite developmentGO:0050773370.868
establishment of organelle localizationGO:00516561220.867
regulation of anatomical structure morphogenesisGO:00226032420.864
synapse organizationGO:00508081960.864
regulation of immune system processGO:00026821760.860
growthGO:00400073590.855
Rat
mitotic spindle organizationGO:00070522200.855
Worm
regulation of phosphate metabolic processGO:00192202100.850
Mouse
fusome organizationGO:0045478130.837
single fertilizationGO:0007338240.836
Worm
defense responseGO:00069523000.834
embryonic pattern specificationGO:00098801740.833
oocyte fate determinationGO:0030716270.820
blastoderm segmentationGO:00073501590.820
cell maturationGO:00484691440.813
immune effector processGO:0002252980.799
oocyte differentiationGO:00099941450.797
embryo development ending in birth or egg hatchingGO:00097921520.797
Worm
male gamete generationGO:00482322010.795
response to organic substanceGO:00100332840.794
Mouse
establishment of localization in cellGO:00516494020.790
positive regulation of response to stimulusGO:00485843230.789
Mouse
actin filament organizationGO:00070151260.785
pole plasm rna localizationGO:0007316520.774
compound eye photoreceptor cell differentiationGO:00017511400.759
positive regulation of cell communicationGO:00106472500.753
Mouse
maternal determination of anterior posterior axis embryoGO:0008358740.751
regulation of cell morphogenesisGO:00226041630.741
positive regulation of cellular component organizationGO:00511301560.741
Rat
determination of adult lifespanGO:00083401370.738
regulation of neurogenesisGO:00507671580.726
regulation of neuron projection developmentGO:0010975690.723
microtubule polymerization or depolymerizationGO:0031109390.720
protein complex assemblyGO:00064612000.719
response to biotic stimulusGO:00096072940.713
regulation of protein metabolic processGO:00512462560.698
brain developmentGO:00074201200.692
cellular response to chemical stimulusGO:00708871990.691
Mouse
establishment of nucleus localizationGO:0040023260.677
anterior posterior axis specification embryoGO:00085951030.675
cellular response to organic substanceGO:00713101320.670
Mouse
organelle fissionGO:00482853400.662
Worm
chorion containing eggshell pattern formationGO:0030381110.646
positive regulation of protein metabolic processGO:00512471280.629
sensory organ morphogenesisGO:00905962600.617
regionalizationGO:00030024160.608
cellular macromolecule localizationGO:00707272200.607
organonitrogen compound metabolic processGO:19015643180.603
Mouse
protein localizationGO:00081042840.597
cell deathGO:00082192790.594
vesicle mediated transportGO:00161923810.593
Worm
regulation of pole plasm oskar mrna localizationGO:0007317270.593
regulation of intracellular signal transductionGO:19025312360.592
Mouse
neuron projection guidanceGO:00974852410.588
cellular component disassemblyGO:0022411460.579
Mouse
regulation of nervous system developmentGO:00519602480.574
ras protein signal transductionGO:0007265880.572
cytoskeleton dependent intracellular transportGO:0030705440.570
ribonucleoside triphosphate metabolic processGO:00091991190.568
Mouse
pole plasm assemblyGO:0007315610.566
positive regulation of signalingGO:00230562430.564
Mouse
immune responseGO:00069552460.551
cognitionGO:00508901410.548
Mouse
innate immune responseGO:00450871440.545
establishment of vesicle localizationGO:0051650510.539
Mouse Worm
cytoplasm organizationGO:0007028640.531
response to external biotic stimulusGO:00432072930.527
organelle assemblyGO:00709251980.526
neuron remodelingGO:0016322290.523
tripartite regional subdivisionGO:00073511030.511
pole plasm oskar mrna localizationGO:0045451460.508
cellular protein complex assemblyGO:0043623710.503
axon developmentGO:00615642970.500
single organism intracellular transportGO:19025822070.496
intracellular mrna localization involved in pattern specification processGO:0060810560.493
rna localizationGO:00064031150.486
regulation of multicellular organismal developmentGO:20000264140.482
positive regulation of phosphate metabolic processGO:00459371390.482
eye morphogenesisGO:00485922600.479
oocyte microtubule cytoskeleton polarizationGO:0008103220.478
actin filament based processGO:00300292200.476
Mouse
nuclear migrationGO:0007097200.461
organic substance catabolic processGO:19015753080.460
Mouse
nucleobase containing small molecule metabolic processGO:00550861740.457
Mouse
compound eye morphogenesisGO:00017452490.452
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:003072260.449
endocytosisGO:00068973100.447
Worm
regulation of response to stressGO:00801342000.444
Mouse
regulation of cellular localizationGO:00603411360.442
spindle organizationGO:00070512530.435
cellular protein localizationGO:00346131600.432
cystoblast divisionGO:0007282100.419
developmental growth involved in morphogenesisGO:0060560650.419
Rat
larval developmentGO:00021641040.419
Worm
programmed cell deathGO:00125012570.412
regulation of microtubule cytoskeleton organizationGO:0070507410.409
multicellular organismal agingGO:00102591400.408
regulation of cell cycle processGO:00105641810.408
response to abiotic stimulusGO:00096283410.408
eggshell formationGO:00307031050.404
positive regulation of macromolecule metabolic processGO:00106044050.400
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.400
synapse assemblyGO:00074161430.398
positive regulation of developmental growthGO:0048639620.393
Rat
apoptotic processGO:00069151590.385
tissue morphogenesisGO:00487292970.385
embryonic development via the syncytial blastodermGO:00017001480.383
regulation of cellular component sizeGO:0032535980.382
Rat
neuron projection extensionGO:1990138320.372
Rat
positive regulation of intracellular signal transductionGO:19025331160.366
single organism behaviorGO:00447083910.365
Human Mouse
oocyte localization involved in germarium derived egg chamber formationGO:0030720120.363
axon cargo transportGO:0008088290.362
purine ribonucleotide metabolic processGO:00091501450.342
Mouse
regulation of localizationGO:00328792750.337
response to other organismGO:00517072930.336
establishment or maintenance of cell polarityGO:00071631670.334
Human Worm
chorion containing eggshell formationGO:00073041050.333
deathGO:00162652840.329
synaptic transmissionGO:00072682880.329
Mouse Worm
positive regulation of signal transductionGO:00099672230.328
Mouse
single organism membrane organizationGO:0044802930.325
Mouse
chromosome organizationGO:00512763600.323
asymmetric protein localizationGO:0008105330.322
Zebrafish
neural precursor cell proliferationGO:0061351750.319
gonad developmentGO:0008406500.315
stem cell developmentGO:0048864790.315
positive regulation of developmental processGO:00510941430.313
Rat
regulation of response to biotic stimulusGO:0002831630.311
ribonucleoside metabolic processGO:00091191270.308
Mouse
muscle structure developmentGO:00610612240.300
actin cytoskeleton reorganizationGO:0031532220.299
embryonic axis specificationGO:00005781070.297
regulation of immune responseGO:00507761180.291
cell adhesionGO:00071551360.291
dendrite morphogenesisGO:00488131990.291
protein complex biogenesisGO:00702712010.290
ribonucleotide metabolic processGO:00092591450.288
Mouse
stem cell differentiationGO:00488631170.288
intracellular mrna localizationGO:0008298660.283
regulation of phosphorus metabolic processGO:00511742100.274
Mouse
female germ line cyst formationGO:0048135420.274
cytokinetic processGO:0032506270.270
organic cyclic compound catabolic processGO:19013611680.265
Mouse
positive regulation of cell differentiationGO:0045597640.264
Rat
compound eye developmentGO:00487493070.262
photoreceptor cell developmentGO:0042461960.262
eye photoreceptor cell developmentGO:0042462810.262
negative regulation of response to stimulusGO:00485852580.259
Mouse
nucleoside metabolic processGO:00091161270.257
Mouse
central nervous system developmentGO:00074172010.256
pseudocleavage involved in syncytial blastoderm formationGO:003058990.255
regulation of phosphorylationGO:00423251470.255
Mouse
positive regulation of molecular functionGO:00440931360.253
asymmetric cell divisionGO:0008356370.253
protein targetingGO:0006605640.250
cellular component assembly involved in morphogenesisGO:00109271510.250
sister chromatid segregationGO:0000819920.248
germ line cyst formationGO:0048134440.248
establishment of protein localizationGO:00451841630.246
dorsal appendage formationGO:0046843470.245
establishment or maintenance of apical basal cell polarityGO:0035088340.242
establishment or maintenance of bipolar cell polarityGO:0061245340.240
microtubule based transportGO:0010970420.235
regulation of organ morphogenesisGO:2000027780.233
positive regulation of phosphorus metabolic processGO:00105621390.232
mitotic cytokinesisGO:0000281500.232
macromolecular complex assemblyGO:00650032560.231
regulation of protein polymerizationGO:0032271280.230
negative regulation of immune system processGO:0002683500.229
homeostatic processGO:00425921990.227
positive regulation of cellular component biogenesisGO:0044089800.225
muscle cell differentiationGO:00426921030.222
protein modification processGO:00362114380.222
positive regulation of rna metabolic processGO:00512542710.209
regulation of immune effector processGO:0002697520.208
regulation of synapse organizationGO:00508071100.206
filopodium assemblyGO:0046847330.206
phenol containing compound metabolic processGO:0018958570.205
regulation of molecular functionGO:00650092170.205
Mouse
tissue migrationGO:00901301550.204
vesicle localizationGO:0051648550.203
Mouse Worm
establishment of epithelial cell polarityGO:0090162130.202
intracellular protein transportGO:00068861040.200
defense response to other organismGO:00985422250.199
hematopoietic or lymphoid organ developmentGO:0048534570.197
Mouse
response to virusGO:0009615280.197
learning or memoryGO:00076111410.193
Mouse
regulation of cell cycleGO:00517262910.192
nucleoside phosphate catabolic processGO:19012921100.191
Mouse
regulation of cell morphogenesis involved in differentiationGO:0010769610.191
organophosphate metabolic processGO:00196371950.186
Mouse
secondary metabolic processGO:0019748750.184
regulation of anatomical structure sizeGO:00900661630.184
Rat
phosphorylationGO:00163102940.181
Mouse
positive regulation of multicellular organismal processGO:00512401430.178
Rat
establishment or maintenance of epithelial cell apical basal polarityGO:0045197240.177
purine containing compound catabolic processGO:00725231120.176
Mouse
microtubule organizing center organizationGO:00310231680.176
body morphogenesisGO:001017120.175
microtubule depolymerizationGO:0007019250.174
organelle transport along microtubuleGO:007238470.174
purine nucleoside triphosphate metabolic processGO:00091441190.169
Mouse
positive regulation of gene expressionGO:00106282900.168
positive regulation of phosphorylationGO:0042327870.168
regulation of axonogenesisGO:0050770320.168
Rat
positive regulation of axonogenesisGO:005077220.167
Rat
dendrite developmentGO:00163582040.167
nucleoside catabolic processGO:00091641120.165
Mouse
mapk cascadeGO:00001651070.162
Mouse
compound eye photoreceptor developmentGO:0042051780.158
regulation of defense response to virusGO:0050688140.156
regulation of protein modification processGO:00313991120.154
response to bacteriumGO:00096171980.154
regulation of embryonic developmentGO:0045995680.153
negative regulation of gene expressionGO:00106293870.153
small gtpase mediated signal transductionGO:0007264880.152
regulation of synapse structure and activityGO:00508031280.147
positive regulation of cell developmentGO:0010720610.145
Rat
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.145
cell cycle phase transitionGO:00447701400.144
cytoplasmic transportGO:00164821300.141
small molecule metabolic processGO:00442813050.141
Mouse
regulation of actin cytoskeleton organizationGO:0032956420.140
synaptic growth at neuromuscular junctionGO:00511241190.140
regulation of microtubule polymerization or depolymerizationGO:0031110270.139
protein localization to organelleGO:0033365820.139
purine nucleotide catabolic processGO:00061951090.137
Mouse
regulation of microtubule depolymerizationGO:0031114240.134
nucleobase containing compound catabolic processGO:00346551650.132
Mouse
anterior posterior axis specificationGO:00099481090.131
spermatid differentiationGO:00485151140.130
Mouse
camera type eye developmentGO:004301040.128
intracellular transportGO:00469072280.128
response to endogenous stimulusGO:00097191190.127
telencephalon developmentGO:002153720.125
Human Mouse
endomembrane system organizationGO:00102561190.123
Mouse
negative regulation of developmental processGO:00510932010.123
germ line stem cell divisionGO:0042078250.123
endosomal transportGO:0016197440.122
nuclear divisionGO:00002803320.121
Worm
nucleocytoplasmic transportGO:0006913720.121
positive regulation of cell projection organizationGO:0031346290.120
Rat
chemical homeostasisGO:0048878920.119
regulation of small gtpase mediated signal transductionGO:0051056930.118
Mouse
development of primary sexual characteristicsGO:0045137500.116
protein polymerizationGO:0051258420.116
positive regulation of transportGO:0051050920.116
cellular response to oxygen containing compoundGO:1901701790.115
positive regulation of nervous system developmentGO:0051962690.114
Rat
regulation of compound eye retinal cell programmed cell deathGO:0046669180.114
reproductive system developmentGO:0061458740.112
reproductive structure developmentGO:0048608740.112
nucleus organizationGO:0006997450.111
Mouse
glycosyl compound catabolic processGO:19016581120.111
Mouse
meiotic cell cycle processGO:19030461320.110
Worm
establishment of mitochondrion localization microtubule mediatedGO:003464360.110
positive regulation of nucleobase containing compound metabolic processGO:00459353320.109
response to heatGO:0009408630.109
retrograde axon cargo transportGO:000809090.109
membrane tubulationGO:009732040.108
male meiosis cytokinesisGO:0007112260.108
axon extensionGO:0048675320.108
Rat
regulation of phosphatase activityGO:001092130.108
purine ribonucleoside triphosphate catabolic processGO:00092071080.107
Mouse
positive regulation of neurogenesisGO:0050769410.107
Rat
response to oxygen containing compoundGO:19017002000.105
regulation of cell sizeGO:0008361630.105
Rat
meiotic cytokinesisGO:0033206330.105
nuclear transportGO:0051169720.102
centrosome organizationGO:00512971630.102
purine nucleoside metabolic processGO:00422781270.102
Mouse
organophosphate catabolic processGO:00464341120.102
Mouse
positive regulation of programmed cell deathGO:0043068620.101
compound eye retinal cell programmed cell deathGO:0046667230.101
cellular response to abiotic stimulusGO:0071214580.101
spindle assemblyGO:0051225800.100
striated muscle cell developmentGO:0055002500.100
eye photoreceptor cell differentiationGO:00017541450.100
purine nucleoside catabolic processGO:00061521120.100
Mouse
establishment of mitochondrion localizationGO:005165470.099
protein localization to plasma membraneGO:0072659130.099
protein phosphorylationGO:00064681690.098
regulation of cellular amine metabolic processGO:003323830.097
cellular catabolic processGO:00442483720.097
Mouse
regulation of actin polymerization or depolymerizationGO:0008064270.097
microtubule polymerizationGO:0046785150.096
positive regulation of growthGO:0045927750.096
Rat
stem cell proliferationGO:0072089880.096
biological adhesionGO:00226101380.095
regulation of cellular protein metabolic processGO:00322682430.093
positive regulation of neuron differentiationGO:0045666260.093
Rat
regulation of protein complex disassemblyGO:0043244290.093
positive regulation of apoptotic processGO:0043065470.093
purine nucleotide metabolic processGO:00061631460.091
Mouse
positive regulation of cellular protein metabolic processGO:00322701180.091
negative regulation of macromolecule biosynthetic processGO:00105582700.090
establishment of protein localization to organelleGO:0072594620.090
melanin metabolic processGO:0006582470.090
cellular protein complex disassemblyGO:0043624350.090
response to ionizing radiationGO:0010212320.089
vesicle organizationGO:0016050440.088
Mouse
ribonucleoside triphosphate catabolic processGO:00092031080.087
Mouse
cellular response to endogenous stimulusGO:0071495800.087
positive regulation of mapk cascadeGO:0043410630.086
germarium derived female germ line cyst encapsulationGO:003070880.086
positive regulation of dendrite morphogenesisGO:005077590.086
positive regulation of cell sizeGO:0045793210.084
regulation of growthGO:00400082330.083
Rat
regulation of cell divisionGO:0051302720.083
digestive tract developmentGO:00485651490.082
cell type specific apoptotic processGO:0097285380.082
regulation of synaptic transmissionGO:0050804690.081
developmental cell growthGO:0048588520.081
Rat
stem cell maintenanceGO:0019827670.080
regulation of defense responseGO:00313471020.080
meiotic cell cycleGO:00513211710.078
Worm
nucleotide catabolic processGO:00091661090.078
Mouse
positive regulation of cell deathGO:0010942690.078
negative regulation of rna metabolic processGO:00512532510.077
positive regulation of axon extensionGO:004577320.076
Rat
negative regulation of cellular metabolic processGO:00313243820.076
Mouse
membrane organizationGO:00610241120.075
Mouse Worm
regulation of catalytic activityGO:00507901850.075
Mouse
regulation of oocyte developmentGO:0060281270.075
regulation of transportGO:00510491810.074
mitotic cell cycle embryonicGO:0045448380.073
regulation of cellular catabolic processGO:00313291570.072
Mouse
retinal cell programmed cell deathGO:0046666250.072
salivary gland developmentGO:00074311620.071
cellular amino acid metabolic processGO:0006520610.071
regulation of response to external stimulusGO:00321011150.071
protein importGO:0017038550.070
catabolic processGO:00090564090.070
Mouse
regulation of cell projection assemblyGO:0060491300.069
molting cycleGO:0042303560.068
response to woundingGO:0009611940.067
regulation of cellular component biogenesisGO:00440872010.067
peptidyl amino acid modificationGO:00181931050.066
cellular amine metabolic processGO:0044106120.066
regulation of apoptotic processGO:00429811300.066
regulation of protein localizationGO:0032880760.066
carbohydrate derivative metabolic processGO:19011352170.066
Mouse
negative regulation of cell cycle phase transitionGO:19019881030.066
regulation of cell maturationGO:1903429270.066
agingGO:00075681430.065
posttranscriptional regulation of gene expressionGO:00106081450.065
negative regulation of nucleobase containing compound metabolic processGO:00459342610.064
striated muscle cell differentiationGO:0051146900.064
amine metabolic processGO:0009308120.064
rhythmic processGO:00485111060.064
meiotic spindle organizationGO:0000212360.063
dorsal ventral axis specificationGO:0009950660.063
forebrain developmentGO:003090020.062
Human Mouse Rat
negative regulation of mitotic cell cycleGO:00459301090.062
defense response to virusGO:0051607230.060
positive regulation of response to external stimulusGO:0032103440.060
positive regulation of transcription dna templatedGO:00458932660.060
pigmentationGO:0043473750.059
nucleoside phosphate metabolic processGO:00067531620.059
Mouse
regulation of ras protein signal transductionGO:0046578930.058
Mouse
purine nucleoside triphosphate catabolic processGO:00091461080.058
Mouse
positive regulation of cellular amine metabolic processGO:003324000.057
chromosome segregationGO:00070591570.057
protein import into nucleusGO:0006606510.057
negative regulation of neurogenesisGO:0050768530.057
Rat
mitotic metaphase plate congressionGO:0007080130.057
positive regulation of multicellular organism growthGO:0040018210.057
cell fate determinationGO:0001709910.056
regulation of actin filament lengthGO:0030832270.056
morphogenesis of embryonic epitheliumGO:0016331940.056
microtubule based movementGO:0007018510.056
establishment of spindle localizationGO:0051293220.055
Human Worm
regulation of cell deathGO:00109411730.055
positive regulation of nitrogen compound metabolic processGO:00511733540.055
axis specificationGO:00097981670.055
regulation of intracellular transportGO:0032386640.054
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.054
positive regulation of apoptotic signaling pathwayGO:200123540.054
hemocyte differentiationGO:0042386380.053
actin filament bundle organizationGO:0061572280.053
regulation of nucleocytoplasmic transportGO:0046822350.052
regulation of programmed cell deathGO:00430671520.052
cell growthGO:00160491080.051
Rat
regulation of multicellular organism growthGO:0040014400.051
positive regulation of erk1 and erk2 cascadeGO:0070374360.050
ribonucleotide catabolic processGO:00092611090.050
Mouse
regulation of cytoskeleton organizationGO:0051493890.050
cytoplasmic microtubule organizationGO:0031122220.049
regulation of multi organism processGO:00439001310.049
mitotic cell cycle phase transitionGO:00447721380.049
regulation of protein localization to nucleusGO:1900180290.048
cellular nitrogen compound catabolic processGO:00442701650.048
Mouse
mitotic sister chromatid segregationGO:0000070870.048
positive regulation of cell cycle processGO:0090068280.047
positive regulation of cellular biosynthetic processGO:00313283160.047
negative regulation of protein metabolic processGO:0051248850.047
imaginal disc derived appendage developmentGO:00487373990.047
nucleoside monophosphate catabolic processGO:0009125390.047
regulation of proteolysisGO:0030162870.046
stem cell divisionGO:0017145690.046
Rat
protein complex disassemblyGO:0043241360.045
regulation of protein import into nucleusGO:0042306280.044
neuron apoptotic processGO:0051402170.044
macromolecular complex disassemblyGO:0032984370.044
positive regulation of neuron projection developmentGO:0010976140.044
Rat
regulation of cytoplasmic transportGO:1903649470.044
organonitrogen compound biosynthetic processGO:19015661170.044
positive regulation of neuron apoptotic processGO:004352510.043
single organism catabolic processGO:00447122280.043
Mouse
protein depolymerizationGO:0051261310.043
cardiovascular system developmentGO:0072358820.042
apical constrictionGO:0003383180.042
regulation of centrosome cycleGO:004660570.042
phagocytosis engulfmentGO:0006911110.042
Worm
cellularizationGO:0007349900.042
protein transportGO:00150311550.041
ribonucleoside monophosphate catabolic processGO:0009158390.041
cellular macromolecular complex assemblyGO:00346221530.041
muscle cell developmentGO:0055001500.041
apoptotic signaling pathwayGO:0097190270.041
sperm individualizationGO:0007291480.041
cell projection assemblyGO:0030031940.040
negative regulation of transcription dna templatedGO:00458922370.040
negative regulation of nitrogen compound metabolic processGO:00511722650.040
engulfment of apoptotic cellGO:004365260.040
Worm
protein targeting to nucleusGO:0044744510.040
asymmetric protein localization involved in cell fate determinationGO:004516790.039
regulation of lamellipodium organizationGO:1902743150.038
nuclear importGO:0051170510.038
regulation of protein dephosphorylationGO:003530450.038
actin polymerization or depolymerizationGO:0008154310.037
regulation of neuron deathGO:1901214260.037
signal transduction by phosphorylationGO:00230141070.037
Mouse
negative regulation of cell differentiationGO:00455961430.037
appendage developmentGO:00487364010.037
response to nutrient levelsGO:00316671140.037

Lis-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.181
charcot marie tooth disease type 2DOID:005053900.058
charcot marie tooth diseaseDOID:1059500.058
nervous system diseaseDOID:86300.058
neuropathyDOID:87000.058
neuromuscular diseaseDOID:44000.058