Drosophila melanogaster

32 known processes

CG8443 (Dmel_CG8443)

CG8443 gene product from transcript CG8443-RA

(Aliases: clu,Dmel\CG8443,anon-WO0118547.143)

CG8443 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
spermatid developmentGO:0007286980.874
spermatid differentiationGO:00485151140.619
mitochondrion morphogenesisGO:007058480.571
germ line stem cell maintenanceGO:0030718500.528
regulation of pole plasm oskar mrna localizationGO:0007317270.409
negative regulation of response to stimulusGO:00485852580.388
organelle fissionGO:00482853400.382
negative regulation of signal transductionGO:00099682060.367
mitochondrion organizationGO:0007005650.363
female germ line stem cell asymmetric divisionGO:0048132140.302
male gamete generationGO:00482322010.296
negative regulation of gene expressionGO:00106293870.286
germ line stem cell divisionGO:0042078250.256
negative regulation of cellular response to oxidative stressGO:190040810.242
negative regulation of signalingGO:00230572190.213
macromolecule catabolic processGO:00090571610.209
organelle localizationGO:00516401480.190
regulation of mitochondrion organizationGO:0010821120.178
mitochondrion localizationGO:0051646170.173
organelle assemblyGO:00709251980.171
negative regulation of cell communicationGO:00106482230.161
mitochondrion degradationGO:000042280.148
purine nucleoside monophosphate metabolic processGO:0009126500.143
autophagyGO:00069141080.137
spermatogenesisGO:00072832000.136
positive regulation of apoptotic signaling pathwayGO:200123540.136
positive regulation of signal transductionGO:00099672230.132
regulation of oocyte developmentGO:0060281270.131
regulation of cytoskeleton organizationGO:0051493890.130
negative regulation of response to oxidative stressGO:190288310.124
regulation of multicellular organismal developmentGO:20000264140.124
regulation of cellular component biogenesisGO:00440872010.120
mrna metabolic processGO:00160711240.119
deathGO:00162652840.119
posttranscriptional regulation of gene expressionGO:00106081450.117
eye developmentGO:00016543230.117
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.116
production of small rna involved in gene silencing by rnaGO:0070918150.113
protein secretionGO:0009306450.109
determination of adult lifespanGO:00083401370.108
female germ line stem cell maintenanceGO:003609980.105
positive regulation of gene expressionGO:00106282900.104
regulation of nuclear transcribed mrna poly a tail shorteningGO:006021140.100
protein acetylationGO:0006473390.099
negative regulation of cytoskeleton organizationGO:0051494300.097
gene silencingGO:00164581380.097
regulation of growthGO:00400082330.095
programmed cell deathGO:00125012570.094
cilium morphogenesisGO:0060271390.093
negative regulation of nitrogen compound metabolic processGO:00511722650.091
actomyosin structure organizationGO:0031032560.091
photoreceptor cell fate commitmentGO:0046552410.090
targeting of mrna for destruction involved in rna interferenceGO:003042340.090
atp metabolic processGO:0046034490.089
regulation of cellular response to insulin stimulusGO:1900076170.086
secretion by cellGO:00329401010.084
gene silencing by mirnaGO:0035195220.082
nucleus organizationGO:0006997450.082
mitochondrial fissionGO:000026680.081
stem cell differentiationGO:00488631170.081
organic acid metabolic processGO:00060821030.079
positive regulation of response to stimulusGO:00485843230.078
lipid storageGO:0019915380.076
germline stem cell asymmetric divisionGO:0098728150.075
negative regulation of immune system processGO:0002683500.072
regulation of organelle organizationGO:00330431960.072
cytoplasmic transport nurse cell to oocyteGO:0007303120.072
nucleoside metabolic processGO:00091161270.071
stem cell divisionGO:0017145690.070
sperm mitochondrion organizationGO:003038270.070
agingGO:00075681430.069
cilium assemblyGO:0042384380.069
rna catabolic processGO:0006401370.068
response to glucoseGO:000974920.066
single organism membrane fusionGO:0044801420.065
posttranscriptional gene silencingGO:0016441460.065
protein depolymerizationGO:0051261310.065
cell deathGO:00082192790.064
nucleoside monophosphate metabolic processGO:0009123520.063
positive regulation of cell communicationGO:00106472500.063
regulation of tube architecture open tracheal systemGO:0035152680.062
nucleoside triphosphate metabolic processGO:00091411200.062
negative regulation of developmental processGO:00510932010.062
negative regulation of phosphorylationGO:0042326350.061
regulation of cell deathGO:00109411730.060
positive regulation of nitrogen compound metabolic processGO:00511733540.060
camera type eye developmentGO:004301040.059
regulation of cell differentiationGO:00455953020.058
purine nucleoside biosynthetic processGO:004245130.058
positive regulation of signalingGO:00230562430.057
neurological system processGO:00508773580.056
dna packagingGO:0006323910.056
response to nitrogen compoundGO:1901698900.055
glycosyl compound catabolic processGO:19016581120.054
regulation of apoptotic processGO:00429811300.054
oxoacid metabolic processGO:00434361030.054
purine nucleoside triphosphate metabolic processGO:00091441190.053
cell cell signaling involved in cell fate commitmentGO:00451682100.053
fusome organizationGO:0045478130.052
skeletal muscle adaptationGO:004350110.052
stem cell maintenanceGO:0019827670.052
negative regulation of intracellular signal transductionGO:1902532570.051
rna splicingGO:0008380830.050
small molecule metabolic processGO:00442813050.050
intracellular transportGO:00469072280.050
regulation of programmed cell deathGO:00430671520.050
response to organonitrogen compoundGO:0010243750.049
insulin receptor signaling pathwayGO:0008286250.049
cellular component assembly involved in morphogenesisGO:00109271510.049
vesicle mediated transportGO:00161923810.049
regulation of response to stressGO:00801342000.049
purine ribonucleoside monophosphate metabolic processGO:0009167500.049
regulation of defense responseGO:00313471020.048
regulation of intracellular signal transductionGO:19025312360.047
purine nucleoside metabolic processGO:00422781270.046
establishment of protein localizationGO:00451841630.046
maintenance of locationGO:0051235730.045
periodic partitioningGO:0007365290.045
translationGO:0006412690.045
cellular nitrogen compound catabolic processGO:00442701650.044
immune system processGO:00023763470.043
posttranscriptional gene silencing by rnaGO:0035194450.043
lipid homeostasisGO:0055088330.043
cellular amino acid metabolic processGO:0006520610.043
imaginal disc pattern formationGO:0007447910.042
response to oxygen containing compoundGO:19017002000.042
cell divisionGO:00513012480.042
oxidation reduction processGO:00551141230.041
wound healingGO:0042060750.041
regulation of cellular response to oxidative stressGO:190040740.040
positive regulation of organelle organizationGO:0010638650.040
cellular response to chemical stimulusGO:00708871990.040
response to organic substanceGO:00100332840.040
heterocycle catabolic processGO:00467001660.039
regulation of cellular amino acid metabolic processGO:000652100.039
regulation of anatomical structure morphogenesisGO:00226032420.038
protein complex disassemblyGO:0043241360.038
multicellular organism growthGO:0035264460.038
mrna catabolic processGO:0006402330.037
ribose phosphate metabolic processGO:00196931450.037
cell projection assemblyGO:0030031940.037
negative regulation of multicellular organismal processGO:00512411420.037
purine ribonucleoside metabolic processGO:00461281270.037
positive regulation of mitochondrion organizationGO:001082280.036
cilium organizationGO:0044782410.036
multicellular organismal agingGO:00102591400.036
regulation of autophagyGO:0010506620.036
cellular response to sterol depletionGO:007150130.035
regionalizationGO:00030024160.035
regulation of membrane potentialGO:0042391350.035
regulation of cellular localizationGO:00603411360.035
purine ribonucleoside biosynthetic processGO:004612930.035
organelle fusionGO:0048284460.034
regulation of secretionGO:0051046440.034
cellular protein complex disassemblyGO:0043624350.034
energy derivation by oxidation of organic compoundsGO:0015980320.034
pole plasm oskar mrna localizationGO:0045451460.033
positive regulation of programmed cell deathGO:0043068620.033
negative regulation of actin filament depolymerizationGO:003083520.033
positive regulation of biosynthetic processGO:00098913160.033
membrane organizationGO:00610241120.033
regulation of molecular functionGO:00650092170.032
ribonucleoside monophosphate metabolic processGO:0009161510.032
detection of light stimulusGO:0009583580.032
sensory perception of soundGO:0007605560.031
ovarian fusome organizationGO:0030723110.031
regulation of mitochondrial fissionGO:009014070.031
developmental programmed cell deathGO:00106231380.031
phosphorylationGO:00163102940.031
negative regulation of nucleobase containing compound metabolic processGO:00459342610.031
negative regulation of insulin receptor signaling pathwayGO:0046627110.031
salivary gland morphogenesisGO:00074351450.031
gland morphogenesisGO:00226121450.029
secretionGO:00469031090.029
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.029
protein localizationGO:00081042840.029
cell adhesionGO:00071551360.028
cellular macromolecule catabolic processGO:00442651360.028
synaptic vesicle localizationGO:0097479530.028
positive regulation of translationGO:0045727120.027
positive regulation of macromolecule biosynthetic processGO:00105572830.027
morphogenesis of a branching structureGO:0001763450.027
cellular response to nitrogen compoundGO:1901699510.027
cellular protein modification processGO:00064644380.027
regulation of meiosisGO:004002030.027
glycosyl compound metabolic processGO:19016571270.027
reproductive system developmentGO:0061458740.027
intracellular signal transductionGO:00355563000.026
cellular component disassemblyGO:0022411460.026
protein targeting to mitochondrionGO:000662610.026
regulation of cellular component sizeGO:0032535980.026
chemotaxisGO:00069352490.025
cellular response to organic substanceGO:00713101320.025
ribonucleoside biosynthetic processGO:004245530.025
regulation of apoptotic signaling pathwayGO:2001233100.025
regulation of insulin receptor signaling pathwayGO:0046626170.025
organophosphate metabolic processGO:00196371950.025
carboxylic acid metabolic processGO:0019752920.025
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288140.024
establishment of mitochondrion localizationGO:005165470.024
thioester metabolic processGO:003538330.024
mitochondrial fusionGO:000805370.024
innate immune responseGO:00450871440.024
regulation of cellular ketone metabolic processGO:001056530.023
detection of external stimulusGO:0009581660.023
regulation of cell maturationGO:1903429270.023
forebrain developmentGO:003090020.023
photoreceptor cell differentiationGO:00465301700.023
positive regulation of developmental growthGO:0048639620.023
sulfur compound metabolic processGO:0006790590.023
positive regulation of cellular component organizationGO:00511301560.022
regulation of protein phosphorylationGO:0001932640.022
ribonucleoprotein complex subunit organizationGO:0071826280.022
organic substance catabolic processGO:19015753080.022
segmentationGO:00352822070.022
rna interferenceGO:0016246270.022
negative regulation of protein depolymerizationGO:1901880230.022
protein phosphorylationGO:00064681690.022
glycosyl compound biosynthetic processGO:190165930.021
detection of stimulusGO:00516061560.021
production of sirna involved in rna interferenceGO:0030422110.021
regulation of actin filament depolymerizationGO:003083430.021
regulation of secretion by cellGO:1903530390.021
regulation of response to oxidative stressGO:190288240.021
intercellular transportGO:001049620.021
purine ribonucleotide metabolic processGO:00091501450.021
nuclear transcribed mrna catabolic processGO:0000956240.021
oocyte maturationGO:000155630.021
nucleoside catabolic processGO:00091641120.021
cytoplasm organizationGO:0007028640.021
catabolic processGO:00090564090.020
cell cycle arrestGO:000705040.020
regulation of membrane depolarizationGO:000325410.020
negative regulation of cell differentiationGO:00455961430.020
dorsal ventral pattern formation imaginal discGO:0007450510.020
cellular response to dsrnaGO:0071359150.020
blastoderm segmentationGO:00073501590.020
positive regulation of cellular biosynthetic processGO:00313283160.020
regulation of immune system processGO:00026821760.020
signal releaseGO:0023061490.020
regulation of actin filament based processGO:0032970420.020
nuclear envelope organizationGO:000699870.020
cellular response to organic cyclic compoundGO:0071407320.019
regulation of immune effector processGO:0002697520.019
neuron fate commitmentGO:0048663500.019
positive regulation of rna metabolic processGO:00512542710.019
aromatic compound catabolic processGO:00194391660.019
regulation of cell growthGO:0001558430.019
chromosome segregationGO:00070591570.019
protein transportGO:00150311550.019
protein modification processGO:00362114380.019
positive regulation of cellular amino acid metabolic processGO:004576400.019
positive regulation of developmental processGO:00510941430.018
enzyme linked receptor protein signaling pathwayGO:00071671790.018
response to woundingGO:0009611940.018
ribonucleotide metabolic processGO:00092591450.018
regulation of protein complex assemblyGO:0043254420.018
regulation of cellular response to stressGO:0080135890.018
purine ribonucleoside catabolic processGO:00461301120.018
response to abiotic stimulusGO:00096283410.018
dorsal ventral pattern formationGO:00099531330.018
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.018
purine nucleotide metabolic processGO:00061631460.018
extrinsic apoptotic signaling pathwayGO:009719110.017
exocytosisGO:0006887280.017
regulation of neuron deathGO:1901214260.017
salivary gland cell autophagic cell deathGO:0035071830.017
negative regulation of cellular metabolic processGO:00313243820.017
biological adhesionGO:00226101380.017
dna conformation changeGO:00711031050.017
homeostatic processGO:00425921990.017
regulation of synapse organizationGO:00508071100.017
regulation of tor signalingGO:0032006210.017
positive regulation of intracellular signal transductionGO:19025331160.017
ion homeostasisGO:0050801550.017
response to endogenous stimulusGO:00097191190.017
gene silencing by rnaGO:0031047570.016
regulation of mrna metabolic processGO:1903311720.016
regulation of response to external stimulusGO:00321011150.016
dsrna fragmentationGO:0031050150.016
positive regulation of cell deathGO:0010942690.016
chromosome condensationGO:0030261410.016
purine ribonucleoside triphosphate metabolic processGO:00092051190.016
purine containing compound metabolic processGO:00725211550.016
reproductive structure developmentGO:0048608740.016
regulation of translationGO:0006417560.016
histolysisGO:00075591020.016
response to external biotic stimulusGO:00432072930.016
single organism membrane organizationGO:0044802930.016
ovarian nurse cell to oocyte transportGO:0007300270.016
regulation of mitochondrial fusionGO:001063550.016
regulation of cellular amine metabolic processGO:003323830.016
gland developmentGO:00487321910.016
salivary gland developmentGO:00074311620.015
single organism intracellular transportGO:19025822070.015
ribonucleoside catabolic processGO:00424541120.015
pole plasm assemblyGO:0007315610.015
inositol lipid mediated signalingGO:004801740.015
embryo development ending in birth or egg hatchingGO:00097921520.015
nucleoside triphosphate catabolic processGO:00091431080.015
acyl coa metabolic processGO:000663730.015
negative regulation of cellular component organizationGO:00511291080.015
female germ line cyst formationGO:0048135420.015
apoptotic processGO:00069151590.015
actin cytoskeleton organizationGO:00300362060.015
nitrogen compound transportGO:0071705850.015
macromolecular complex disassemblyGO:0032984370.015
growthGO:00400073590.015
cellular respirationGO:0045333260.015
cellular amine metabolic processGO:0044106120.015
imaginal disc derived wing vein morphogenesisGO:0008586440.015
response to biotic stimulusGO:00096072940.015
cell migrationGO:00164772380.015
purine ribonucleoside triphosphate catabolic processGO:00092071080.015
hemopoiesisGO:0030097460.015
positive regulation of growthGO:0045927750.014
protein complex assemblyGO:00064612000.014
purine nucleoside monophosphate catabolic processGO:0009128380.014
morphogenesis of an epitheliumGO:00020092760.014
mitotic sister chromatid segregationGO:0000070870.014
establishment of organelle localizationGO:00516561220.014
positive regulation of apoptotic processGO:0043065470.014
reactive oxygen species metabolic processGO:0072593220.014
erbb signaling pathwayGO:0038127580.014
mitotic chromosome condensationGO:0007076220.014
ribonucleoprotein complex biogenesisGO:0022613310.014
ribonucleoside monophosphate catabolic processGO:0009158390.014
regulation of embryonic pattern specificationGO:1902875270.014
cellular macromolecule localizationGO:00707272200.014
cellular response to biotic stimulusGO:007121640.014
negative regulation of rna metabolic processGO:00512532510.014
kidney developmentGO:000182230.014
wing disc pattern formationGO:0035222660.014
nucleoside biosynthetic processGO:000916330.014
mitochondrion distributionGO:0048311100.014
purine nucleotide catabolic processGO:00061951090.014
golgi organizationGO:0007030660.014
positive regulation of multicellular organism growthGO:0040018210.013
cardiovascular system developmentGO:0072358820.013
negative regulation of gene expression epigeneticGO:0045814770.013
carbohydrate derivative metabolic processGO:19011352170.013
dna methylationGO:000630640.013
hematopoietic or lymphoid organ developmentGO:0048534570.013
positive regulation of protein metabolic processGO:00512471280.013
purine ribonucleotide catabolic processGO:00091541090.013
atp catabolic processGO:0006200380.013
purine nucleoside catabolic processGO:00061521120.013
salivary gland histolysisGO:0035070880.013
dna metabolic processGO:00062592270.013
regulation of gene silencingGO:0060968630.013
apoptotic signaling pathwayGO:0097190270.013
lipid localizationGO:0010876540.013
female sex differentiationGO:0046660200.012
cell motilityGO:00488702510.012
mrna splicing via spliceosomeGO:0000398730.012
branching morphogenesis of an epithelial tubeGO:0048754450.012
ribonucleoside metabolic processGO:00091191270.012
production of mirnas involved in gene silencing by mirnaGO:0035196100.012
endocytosisGO:00068973100.012
establishment of localization in cellGO:00516494020.012
establishment of vesicle localizationGO:0051650510.012
carbohydrate derivative catabolic processGO:19011361180.012
dephosphorylationGO:0016311510.012
single organism cellular localizationGO:19025801800.012
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.012
stem cell developmentGO:0048864790.012
response to organophosphorusGO:004668320.012
organic substance transportGO:00717022570.011
embryonic pattern specificationGO:00098801740.011
nucleobase containing compound catabolic processGO:00346551650.011
response to bacteriumGO:00096171980.011
nucleotide catabolic processGO:00091661090.011
striated muscle tissue developmentGO:0014706270.011
cellular lipid metabolic processGO:0044255830.011
positive regulation of transportGO:0051050920.011
ncrna metabolic processGO:0034660430.011
compound eye developmentGO:00487493070.011
generation of precursor metabolites and energyGO:0006091420.011
nucleus localizationGO:0051647340.011
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.011
cell proliferationGO:00082832990.011
chaeta developmentGO:0022416970.011
skeletal muscle organ developmentGO:0060538480.011
protein localization to mitochondrionGO:007058510.011
oocyte developmentGO:00485991240.011
endomembrane system organizationGO:00102561190.011
ribonucleoprotein complex assemblyGO:0022618230.011
negative regulation of cell proliferationGO:0008285690.011
extracellular structure organizationGO:0043062460.011
small rna loading onto riscGO:007092260.011
regulation of intracellular transportGO:0032386640.011
purine containing compound catabolic processGO:00725231120.011
intracellular protein transportGO:00068861040.011
actin filament depolymerizationGO:003004250.011
tor signalingGO:0031929320.011
regulation of mitochondrial membrane potentialGO:005188120.011
immune system developmentGO:0002520570.011
defense response to other organismGO:00985422250.011
exocrine system developmentGO:00352721620.010
purine nucleoside triphosphate catabolic processGO:00091461080.010
nucleoside monophosphate catabolic processGO:0009125390.010
cytoplasmic transportGO:00164821300.010
cellular response to insulin stimulusGO:0032869280.010
positive regulation of rna biosynthetic processGO:19026802660.010
ribonucleotide catabolic processGO:00092611090.010
axon guidanceGO:00074112330.010
organonitrogen compound metabolic processGO:19015643180.010
actin filament organizationGO:00070151260.010
adult somatic muscle developmentGO:0007527140.010
gonad developmentGO:0008406500.010
central nervous system developmentGO:00074172010.010
macromolecular complex assemblyGO:00650032560.010
meiotic nuclear divisionGO:00071261510.010
germarium derived egg chamber formationGO:00072931010.010
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.010
morphogenesis of follicular epitheliumGO:0016333360.010

CG8443 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.060
disease of anatomical entityDOID:700.060
central nervous system diseaseDOID:33100.020
synucleinopathyDOID:005089000.020
neurodegenerative diseaseDOID:128900.020
nervous system diseaseDOID:86300.020
disease of metabolismDOID:001466700.017
muscular diseaseDOID:008000000.016
myopathyDOID:42300.016
muscle tissue diseaseDOID:6600.016
parkinson s diseaseDOID:1433000.013
sensory system diseaseDOID:005015500.013
eye and adnexa diseaseDOID:149200.013