IMP: Integrative Multi-species Prediction

Drosophila melanogaster

100 known processes

msl-3 (Dmel_CG8631)

male-specific lethal 3

(Aliases: MSL-3,MSL3,msl,Msl3,mle(3)132,Dmel\CG8631,CG8631,MSL,msl3,mls3,mle3,DmMsl-3,Msl 1-3)

Entrez: 38779
FLYBASE: FBgn0002775
UniProtKB: P50536

Process Predictions
Disease Predictions

msl-3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
histone h4 acetylation	GO:0043967	13	0.875	Human
internal peptidyl lysine acetylation	GO:0018393	38	0.869	Human
peptidyl lysine modification	GO:0018205	57	0.844	Human
protein acylation	GO:0043543	42	0.785	Human
chromatin organization	GO:0006325	207	0.736	Human
peptidyl lysine acetylation	GO:0018394	39	0.713	Human
histone modification	GO:0016570	106	0.660	Human
chromatin modification	GO:0016568	147	0.646	Human
protein acetylation	GO:0006473	39	0.574	Human
histone acetylation	GO:0016573	38	0.549	Human
histone h4 k16 acetylation	GO:0043984	4	0.542	Human
internal protein amino acid acetylation	GO:0006475	38	0.431	Human
chromosome organization	GO:0051276	360	0.413	Human
covalent chromatin modification	GO:0016569	106	0.404	Human
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.396
positive regulation of rna biosynthetic process	GO:1902680	266	0.357
dna metabolic process	GO:0006259	227	0.327
regulation of gene expression epigenetic	GO:0040029	128	0.294
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.291
negative regulation of rna metabolic process	GO:0051253	251	0.257
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.254
negative regulation of rna biosynthetic process	GO:1902679	240	0.234
positive regulation of rna metabolic process	GO:0051254	271	0.229
positive regulation of transcription dna templated	GO:0045893	266	0.226
regionalization	GO:0003002	416	0.192
dosage compensation	GO:0007549	16	0.177
heterochromatin organization	GO:0070828	25	0.144
axonogenesis	GO:0007409	290	0.141
positive regulation of biosynthetic process	GO:0009891	316	0.135
negative regulation of gene expression	GO:0010629	387	0.134
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.132
positive regulation of cellular biosynthetic process	GO:0031328	316	0.132
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.131
regulation of cell cycle process	GO:0010564	181	0.130
taxis	GO:0042330	304	0.130
transcription from rna polymerase ii promoter	GO:0006366	368	0.124
chromatin assembly or disassembly	GO:0006333	52	0.117
negative regulation of chromatin silencing	GO:0031936	9	0.113
negative regulation of transcription dna templated	GO:0045892	237	0.110
dna conformation change	GO:0071103	105	0.103
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.102
regulation of histone acetylation	GO:0035065	7	0.101
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.101
negative regulation of biosynthetic process	GO:0009890	277	0.098
organelle fission	GO:0048285	340	0.098
protein modification by small protein conjugation or removal	GO:0070647	106	0.096
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.095
cellular macromolecule localization	GO:0070727	220	0.090
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.090
negative regulation of cellular biosynthetic process	GO:0031327	277	0.084
meiotic nuclear division	GO:0007126	151	0.083
regulation of organelle organization	GO:0033043	196	0.083
meiotic cell cycle	GO:0051321	171	0.081
defense response	GO:0006952	300	0.079
innate immune response	GO:0045087	144	0.079
regulation of multicellular organismal development	GO:2000026	414	0.078
imaginal disc derived wing morphogenesis	GO:0007476	337	0.078
atp dependent chromatin remodeling	GO:0043044	22	0.078
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.076
segmentation	GO:0035282	207	0.075
dna integrity checkpoint	GO:0031570	81	0.074
mitotic chromosome condensation	GO:0007076	22	0.074
growth	GO:0040007	359	0.072
small molecule metabolic process	GO:0044281	305	0.072
oocyte differentiation	GO:0009994	145	0.072
regulation of chromatin silencing	GO:0031935	36	0.071
dna packaging	GO:0006323	91	0.071
male gamete generation	GO:0048232	201	0.071
protein modification process	GO:0036211	438	0.071	Human
morphogenesis of an epithelium	GO:0002009	276	0.069
protein localization	GO:0008104	284	0.068
axon guidance	GO:0007411	233	0.066
cellular catabolic process	GO:0044248	372	0.066
mitotic dna integrity checkpoint	GO:0044774	75	0.065
regulation of dna metabolic process	GO:0051052	34	0.064
imaginal disc derived wing vein specification	GO:0007474	48	0.064
neuron projection guidance	GO:0097485	241	0.061
oocyte axis specification	GO:0007309	108	0.061
dna damage checkpoint	GO:0000077	78	0.059
regulation of mitotic cell cycle	GO:0007346	190	0.059
cellular amino acid metabolic process	GO:0006520	61	0.059
appendage morphogenesis	GO:0035107	397	0.056
chromatin silencing	GO:0006342	76	0.056
tissue morphogenesis	GO:0048729	297	0.056
anterior posterior pattern specification	GO:0009952	136	0.053
protein localization to organelle	GO:0033365	82	0.053
heterochromatin organization involved in chromatin silencing	GO:0070868	9	0.052
chromatin remodeling	GO:0006338	72	0.052
axon development	GO:0061564	297	0.052
histone exchange	GO:0043486	21	0.051
regulation of heterochromatin assembly	GO:0031445	8	0.051
cellular response to dna damage stimulus	GO:0006974	223	0.050
positive regulation of gene expression	GO:0010628	290	0.049
chemotaxis	GO:0006935	249	0.049
single organism cellular localization	GO:1902580	180	0.048
ovarian follicle cell development	GO:0030707	248	0.047
organic substance catabolic process	GO:1901575	308	0.047
chromosome segregation	GO:0007059	157	0.046
anterior posterior axis specification	GO:0009948	109	0.046
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.046
developmental maturation	GO:0021700	172	0.045
organonitrogen compound metabolic process	GO:1901564	318	0.045
vesicle mediated transport	GO:0016192	381	0.045
regulation of response to stress	GO:0080134	200	0.045
oxoacid metabolic process	GO:0043436	103	0.044
dna repair	GO:0006281	54	0.044
mitotic dna damage checkpoint	GO:0044773	74	0.043
establishment of localization in cell	GO:0051649	402	0.043
organic substance transport	GO:0071702	257	0.042
protein ubiquitination	GO:0016567	70	0.042
single organism intracellular transport	GO:1902582	207	0.042
regulation of gene silencing	GO:0060968	63	0.041
death	GO:0016265	284	0.041
cell proliferation	GO:0008283	299	0.040
regulation of cell development	GO:0060284	215	0.040
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.040
posttranscriptional regulation of gene expression	GO:0010608	145	0.040
developmental growth	GO:0048589	280	0.040
cellular protein modification process	GO:0006464	438	0.040	Human
macromolecular complex assembly	GO:0065003	256	0.039
protein dna complex subunit organization	GO:0071824	86	0.039
eye morphogenesis	GO:0048592	260	0.039
dna methylation	GO:0006306	4	0.039
sister chromatid segregation	GO:0000819	92	0.038
positive regulation of response to stimulus	GO:0048584	323	0.038
regulation of chromatin assembly	GO:0010847	9	0.037
compound eye photoreceptor cell differentiation	GO:0001751	140	0.036
negative regulation of cell cycle process	GO:0010948	109	0.036
cellular ketone metabolic process	GO:0042180	24	0.036
cellular protein localization	GO:0034613	160	0.036
peptidyl amino acid modification	GO:0018193	105	0.035	Human
heterocycle catabolic process	GO:0046700	166	0.035
peptidyl lysine methylation	GO:0018022	16	0.035
ribose phosphate metabolic process	GO:0019693	145	0.035
reproductive system development	GO:0061458	74	0.035
protein complex biogenesis	GO:0070271	201	0.035
carboxylic acid metabolic process	GO:0019752	92	0.034
regulation of chromatin modification	GO:1903308	28	0.034
cellular nitrogen compound catabolic process	GO:0044270	165	0.034
defense response to bacterium	GO:0042742	178	0.034
dna alkylation	GO:0006305	4	0.033
germ cell migration	GO:0008354	43	0.033
glycosyl compound metabolic process	GO:1901657	127	0.032
protein modification by small protein conjugation	GO:0032446	79	0.032
spermatogenesis	GO:0007283	200	0.032
mitotic spindle organization	GO:0007052	220	0.032
response to bacterium	GO:0009617	198	0.032
response to external biotic stimulus	GO:0043207	293	0.032
regulation of immune system process	GO:0002682	176	0.032
organic acid metabolic process	GO:0006082	103	0.031
programmed cell death	GO:0012501	257	0.031
nuclear division	GO:0000280	332	0.031
eggshell chorion assembly	GO:0007306	66	0.031
aromatic compound catabolic process	GO:0019439	166	0.031
response to temperature stimulus	GO:0009266	106	0.031
negative regulation of cellular metabolic process	GO:0031324	382	0.031
regulation of neurogenesis	GO:0050767	158	0.031
regulation of response to gamma radiation	GO:2001228	4	0.031
oocyte anterior posterior axis specification	GO:0007314	72	0.031
purine ribonucleoside metabolic process	GO:0046128	127	0.030
pole plasm rna localization	GO:0007316	52	0.030
endocytosis	GO:0006897	310	0.030
gene silencing	GO:0016458	138	0.030
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	18	0.030
histone lysine demethylation	GO:0070076	6	0.029
post embryonic appendage morphogenesis	GO:0035120	385	0.029
establishment of protein localization	GO:0045184	163	0.029
nucleobase containing compound catabolic process	GO:0034655	165	0.029
nucleoside catabolic process	GO:0009164	112	0.029
regulation of notch signaling pathway	GO:0008593	100	0.029
heterochromatin assembly	GO:0031507	13	0.029
dendrite development	GO:0016358	204	0.029
macromolecule catabolic process	GO:0009057	161	0.029
regulation of cell death	GO:0010941	173	0.029
cell death	GO:0008219	279	0.028
nucleoside triphosphate catabolic process	GO:0009143	108	0.028
response to ionizing radiation	GO:0010212	32	0.028
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.028
purine ribonucleotide metabolic process	GO:0009150	145	0.028
intracellular transport	GO:0046907	228	0.028
regulation of chromatin organization	GO:1902275	32	0.028
defense response to other organism	GO:0098542	225	0.027
regulation of cellular localization	GO:0060341	136	0.027
notch signaling pathway	GO:0007219	120	0.027
meiotic cell cycle process	GO:1903046	132	0.027
cell maturation	GO:0048469	144	0.027
nucleoside metabolic process	GO:0009116	127	0.027
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.027
regulation of growth	GO:0040008	233	0.027
chemical homeostasis	GO:0048878	92	0.027
columnar cuboidal epithelial cell development	GO:0002066	249	0.026
eggshell formation	GO:0030703	105	0.026
response to other organism	GO:0051707	293	0.026
embryonic axis specification	GO:0000578	107	0.026
mitotic cell cycle phase transition	GO:0044772	138	0.026
stem cell differentiation	GO:0048863	117	0.026
blastoderm segmentation	GO:0007350	159	0.026
organic cyclic compound catabolic process	GO:1901361	168	0.025
ribonucleoside catabolic process	GO:0042454	112	0.025
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.025
body morphogenesis	GO:0010171	2	0.025
histone ubiquitination	GO:0016574	4	0.025
anterior posterior axis specification embryo	GO:0008595	103	0.024
neurological system process	GO:0050877	358	0.024
cell fate specification	GO:0001708	71	0.024
regulation of catabolic process	GO:0009894	170	0.024
determination of adult lifespan	GO:0008340	137	0.024
stem cell division	GO:0017145	69	0.024
wing disc morphogenesis	GO:0007472	344	0.024
positive regulation of gene expression epigenetic	GO:0045815	16	0.024
organic hydroxy compound metabolic process	GO:1901615	83	0.024
carbohydrate derivative metabolic process	GO:1901135	217	0.024
regulation of developmental growth	GO:0048638	174	0.023
cellular response to chemical stimulus	GO:0070887	199	0.023
purine containing compound metabolic process	GO:0072521	155	0.023
posttranscriptional gene silencing	GO:0016441	46	0.023
compound eye development	GO:0048749	307	0.023
regulation of chromosome organization	GO:0033044	64	0.023
embryonic pattern specification	GO:0009880	174	0.023
amine metabolic process	GO:0009308	12	0.023
positive regulation of cellular amine metabolic process	GO:0033240	0	0.023
pole plasm assembly	GO:0007315	61	0.022
organonitrogen compound catabolic process	GO:1901565	128	0.022
protein complex assembly	GO:0006461	200	0.022
cuticle development	GO:0042335	86	0.022
regulation of molecular function	GO:0065009	217	0.022
immune system process	GO:0002376	347	0.022
purine nucleoside metabolic process	GO:0042278	127	0.022
dna recombination	GO:0006310	32	0.022
imaginal disc derived appendage development	GO:0048737	399	0.021
embryonic development via the syncytial blastoderm	GO:0001700	148	0.021
response to abiotic stimulus	GO:0009628	341	0.021
purine nucleotide catabolic process	GO:0006195	109	0.021
mitotic g2 m transition checkpoint	GO:0044818	70	0.021
cell cycle phase transition	GO:0044770	140	0.021
cellularization	GO:0007349	90	0.021
regulation of cell cycle phase transition	GO:1901987	130	0.021
regulation of cellular amino acid metabolic process	GO:0006521	0	0.021
tripartite regional subdivision	GO:0007351	103	0.021
purine nucleoside catabolic process	GO:0006152	112	0.021
immune response	GO:0006955	246	0.021
spermatid differentiation	GO:0048515	114	0.021
oocyte construction	GO:0007308	112	0.020
g2 dna damage checkpoint	GO:0031572	69	0.020
catabolic process	GO:0009056	409	0.020
epithelial cell differentiation	GO:0030855	322	0.020
negative regulation of gene expression epigenetic	GO:0045814	77	0.020
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.020
apoptotic process	GO:0006915	159	0.020
negative regulation of bmp signaling pathway	GO:0030514	12	0.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.020
multi multicellular organism process	GO:0044706	123	0.020
negative regulation of cell communication	GO:0010648	223	0.020
axis specification	GO:0009798	167	0.020
spindle organization	GO:0007051	253	0.019
epithelial cell development	GO:0002064	274	0.019
eye photoreceptor cell development	GO:0042462	81	0.019
regulation of autophagy	GO:0010506	62	0.019
ribonucleoside metabolic process	GO:0009119	127	0.019
cellular component assembly involved in morphogenesis	GO:0010927	151	0.019
regulation of multi organism process	GO:0043900	131	0.019
protein transport	GO:0015031	155	0.019
neuroblast differentiation	GO:0014016	29	0.019
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.019
regulation of cellular amine metabolic process	GO:0033238	3	0.019
mitotic g2 dna damage checkpoint	GO:0007095	69	0.019
signal transduction in response to dna damage	GO:0042770	3	0.019
cytoplasmic transport	GO:0016482	130	0.019
phagocytosis	GO:0006909	215	0.019
sensory perception	GO:0007600	196	0.018
oocyte development	GO:0048599	124	0.018
ommochrome metabolic process	GO:0046152	19	0.018
targeting of mrna for destruction involved in rna interference	GO:0030423	4	0.018
cell cycle checkpoint	GO:0000075	95	0.018
compound eye photoreceptor development	GO:0042051	78	0.018
eye development	GO:0001654	323	0.018
dorsal ventral pattern formation imaginal disc	GO:0007450	51	0.017
purine ribonucleoside catabolic process	GO:0046130	112	0.017
cellular amine metabolic process	GO:0044106	12	0.017
dna methylation or demethylation	GO:0044728	4	0.017
cellular macromolecule catabolic process	GO:0044265	136	0.017
appendage development	GO:0048736	401	0.017
positive regulation of proteolysis	GO:0045862	52	0.017
positive regulation of cellular catabolic process	GO:0031331	95	0.017
negative regulation of programmed cell death	GO:0043069	72	0.017
histone h3 acetylation	GO:0043966	11	0.017
sterol homeostasis	GO:0055092	4	0.017
pigment metabolic process involved in pigmentation	GO:0043474	33	0.017
response to biotic stimulus	GO:0009607	294	0.017
negative regulation of cell differentiation	GO:0045596	143	0.017
regulation of transcription by chromatin organization	GO:0034401	3	0.017
regulation of defense response	GO:0031347	102	0.017
intracellular mrna localization	GO:0008298	66	0.017
production of sirna involved in rna interference	GO:0030422	11	0.017
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.017
nucleobase containing small molecule metabolic process	GO:0055086	174	0.016
negative regulation of response to stimulus	GO:0048585	258	0.016
eye photoreceptor cell differentiation	GO:0001754	145	0.016
ovarian follicle cell stalk formation	GO:0030713	17	0.016
protein catabolic process	GO:0030163	101	0.016
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.016
regulation of apoptotic process	GO:0042981	130	0.016
compound eye cone cell differentiation	GO:0042675	13	0.016
organophosphate metabolic process	GO:0019637	195	0.016
regulation of cell differentiation	GO:0045595	302	0.016
nucleoside phosphate metabolic process	GO:0006753	162	0.016
cell division	GO:0051301	248	0.015
nucleoside triphosphate metabolic process	GO:0009141	120	0.015
photoreceptor cell differentiation	GO:0046530	170	0.015
positive regulation of immune system process	GO:0002684	68	0.015
cellular response to abiotic stimulus	GO:0071214	58	0.015
regulation of synapse structure and activity	GO:0050803	128	0.015
regulation of bmp signaling pathway	GO:0030510	23	0.015
purine ribonucleotide catabolic process	GO:0009154	109	0.015
gene silencing by rna	GO:0031047	57	0.015
salivary gland histolysis	GO:0035070	88	0.015
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.015
kidney epithelium development	GO:0072073	3	0.015
regulation of cellular ketone metabolic process	GO:0010565	3	0.015
response to organophosphorus	GO:0046683	2	0.015
negative regulation of cell cycle	GO:0045786	116	0.015
positive regulation of cell communication	GO:0010647	250	0.014
telomere maintenance	GO:0000723	21	0.014
positive regulation of signal transduction	GO:0009967	223	0.014
carbohydrate derivative catabolic process	GO:1901136	118	0.014
multi organism behavior	GO:0051705	175	0.014
bmp signaling pathway	GO:0030509	27	0.014
negative regulation of cell cycle phase transition	GO:1901988	103	0.014
rna localization	GO:0006403	115	0.014
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.014
dendrite morphogenesis	GO:0048813	199	0.014
regulation of dna templated transcription in response to stress	GO:0043620	4	0.014
regulation of cellular response to oxidative stress	GO:1900407	4	0.014
negative regulation of photoreceptor cell differentiation	GO:0046533	8	0.014
regulation of protein acetylation	GO:1901983	7	0.014
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.014
mitotic nuclear division	GO:0007067	213	0.014
oocyte maturation	GO:0001556	3	0.014
negative regulation of signal transduction	GO:0009968	206	0.014
regulation of establishment of protein localization	GO:0070201	61	0.013
malpighian tubule morphogenesis	GO:0007443	44	0.013
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	4	0.013
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.013
renal tubule development	GO:0061326	64	0.013
embryonic hemopoiesis	GO:0035162	26	0.013
positive regulation of organelle organization	GO:0010638	65	0.013
imaginal disc pattern formation	GO:0007447	91	0.013
regulation of meiosis	GO:0040020	3	0.013
lipid metabolic process	GO:0006629	121	0.013
ommochrome biosynthetic process	GO:0006727	19	0.013
production of small rna involved in gene silencing by rna	GO:0070918	15	0.013
imaginal disc fusion thorax closure	GO:0046529	19	0.013
l amino acid import	GO:0043092	2	0.013
embryo development ending in birth or egg hatching	GO:0009792	152	0.013
central nervous system development	GO:0007417	201	0.013
positive regulation of molecular function	GO:0044093	136	0.013
ocellus pigmentation	GO:0033060	19	0.013
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.013
proteolysis	GO:0006508	192	0.013
regulation of localization	GO:0032879	275	0.013
ribonucleotide metabolic process	GO:0009259	145	0.013
anterograde axon cargo transport	GO:0008089	6	0.013
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.013
wing disc pattern formation	GO:0035222	66	0.013
intracellular protein transport	GO:0006886	104	0.013
rna catabolic process	GO:0006401	37	0.013
negative regulation of developmental process	GO:0051093	201	0.013
dorsal ventral pattern formation	GO:0009953	133	0.013
regulation of dna recombination	GO:0000018	4	0.012
retina development in camera type eye	GO:0060041	4	0.012
posttranscriptional gene silencing by rna	GO:0035194	45	0.012
photoreceptor cell development	GO:0042461	96	0.012
sensory organ morphogenesis	GO:0090596	260	0.012
pole plasm oskar mrna localization	GO:0045451	46	0.012
transposition	GO:0032196	13	0.012
single organism catabolic process	GO:0044712	228	0.012
atp metabolic process	GO:0046034	49	0.012
cellular response to external stimulus	GO:0071496	66	0.012
negative regulation of growth	GO:0045926	84	0.012
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.012
ethanolamine containing compound metabolic process	GO:0042439	4	0.012
gland morphogenesis	GO:0022612	145	0.012
regulation of cellular response to stress	GO:0080135	89	0.012
positive regulation of macromolecule metabolic process	GO:0010604	405	0.012
peptidyl lysine dimethylation	GO:0018027	3	0.012
regulation of protein localization	GO:0032880	76	0.012
ribonucleotide catabolic process	GO:0009261	109	0.011
purine nucleotide metabolic process	GO:0006163	146	0.011
pigment metabolic process	GO:0042440	84	0.011
negative regulation of cell death	GO:0060548	81	0.011
single organism biosynthetic process	GO:0044711	206	0.011
regulation of cell division	GO:0051302	72	0.011
regulation of response to dna damage stimulus	GO:2001020	23	0.011
reproductive structure development	GO:0048608	74	0.011
response to organic substance	GO:0010033	284	0.011
morphogenesis of follicular epithelium	GO:0016333	36	0.011
meiotic chromosome segregation	GO:0045132	59	0.011
regulation of cellular catabolic process	GO:0031329	157	0.011
spinal cord dorsal ventral patterning	GO:0021513	1	0.011
regulation of embryonic development	GO:0045995	68	0.011
regulation of cell cycle	GO:0051726	291	0.011
telencephalon development	GO:0021537	2	0.011
neural precursor cell proliferation	GO:0061351	75	0.011
male meiosis	GO:0007140	52	0.011
open tracheal system development	GO:0007424	204	0.011
microtubule organizing center organization	GO:0031023	168	0.011
eggshell chorion gene amplification	GO:0007307	9	0.011
purine containing compound catabolic process	GO:0072523	112	0.011
male courtship behavior veined wing extension	GO:0048065	22	0.011
regulation of response to biotic stimulus	GO:0002831	63	0.011
regulation of photoreceptor cell differentiation	GO:0046532	34	0.011
negative regulation of cellular response to oxidative stress	GO:1900408	1	0.011
chitin based cuticle development	GO:0040003	49	0.011
digestive system development	GO:0055123	149	0.011
homeostatic process	GO:0042592	199	0.011
cilium morphogenesis	GO:0060271	39	0.011
regulation of translation	GO:0006417	56	0.011
chorion containing eggshell formation	GO:0007304	105	0.011
membrane organization	GO:0061024	112	0.011
regulation of response to oxidative stress	GO:1902882	4	0.011
hindgut development	GO:0061525	58	0.011
chromosome condensation	GO:0030261	41	0.011
establishment of protein localization to organelle	GO:0072594	62	0.011
embryonic hindgut morphogenesis	GO:0048619	48	0.011
epithelial tube morphogenesis	GO:0060562	88	0.011
compound eye photoreceptor fate commitment	GO:0001752	36	0.011
defense response to gram negative bacterium	GO:0050829	94	0.010
morphogenesis of a branching epithelium	GO:0061138	45	0.010
stem cell maintenance	GO:0019827	67	0.010
regulation of apoptotic signaling pathway	GO:2001233	10	0.010
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.010
small rna loading onto risc	GO:0070922	6	0.010
cellular response to nitrogen compound	GO:1901699	51	0.010
secondary metabolic process	GO:0019748	75	0.010
learning	GO:0007612	75	0.010
regulation of compound eye cone cell fate specification	GO:0042682	4	0.010
cytokinesis	GO:0000910	90	0.010
cytoskeleton dependent cytokinesis	GO:0061640	81	0.010
protein kinase b signaling	GO:0043491	1	0.010
peptidyl lysine trimethylation	GO:0018023	6	0.010
mrna metabolic process	GO:0016071	124	0.010

msl-3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.030
organ system cancer	DOID:0050686	0.023
cancer	DOID:162	0.023
disease of cellular proliferation	DOID:14566	0.023

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