Drosophila melanogaster

180 known processes

Cul-4 (Dmel_CG8711)

Cullin-4

(Aliases: CG8711,DMcul-4,Cul4,CUL4,Dmel\CG8711,dCul4,cul-4)

Cul-4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
epithelial cell differentiationGO:00308553220.613
protein catabolic processGO:00301631010.559
macromolecule catabolic processGO:00090571610.462
cellular macromolecule catabolic processGO:00442651360.374
Mouse
regulation of catabolic processGO:00098941700.351
organelle fissionGO:00482853400.318
protein modification by small protein conjugation or removalGO:00706471060.277
Human
protein ubiquitinationGO:0016567700.233
Human
histone modificationGO:00165701060.227
Human
ubiquitin dependent protein catabolic processGO:0006511780.208
Mouse
body morphogenesisGO:001017120.201
cellular amino acid metabolic processGO:0006520610.183
cell cycle phase transitionGO:00447701400.176
regulation of cellular ketone metabolic processGO:001056530.174
positive regulation of catabolic processGO:00098961050.169
regulation of cell cycle processGO:00105641810.162
histone acetylationGO:0016573380.162
regulation of cellular amine metabolic processGO:003323830.155
single organism cellular localizationGO:19025801800.150
regulation of protein catabolic processGO:0042176550.140
columnar cuboidal epithelial cell differentiationGO:00020652560.138
organic substance catabolic processGO:19015753080.133
proteolysis involved in cellular protein catabolic processGO:0051603830.129
Mouse
transcription from rna polymerase ii promoterGO:00063663680.124
regulation of cellular amino acid metabolic processGO:000652100.121
posttranscriptional gene silencing by rnaGO:0035194450.116
male gamete generationGO:00482322010.115
covalent chromatin modificationGO:00165691060.107
Human
regulation of cell cycle phase transitionGO:19019871300.107
rna transportGO:0050658460.106
mitotic dna damage checkpointGO:0044773740.104
cellular protein modification processGO:00064644380.096
Human
mrna metabolic processGO:00160711240.094
growthGO:00400073590.093
protein complex biogenesisGO:00702712010.087
positive regulation of protein metabolic processGO:00512471280.082
carboxylic acid metabolic processGO:0019752920.081
protein complex assemblyGO:00064612000.077
spermatid differentiationGO:00485151140.074
cell proliferationGO:00082832990.074
Mouse
chromatin remodelingGO:0006338720.072
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288140.071
amine metabolic processGO:0009308120.070
proteolysisGO:00065081920.069
Mouse
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.067
regulation of cellular protein metabolic processGO:00322682430.060
nucleobase containing compound transportGO:0015931560.060
posttranscriptional gene silencingGO:0016441460.059
regulation of protein metabolic processGO:00512462560.058
mrna catabolic processGO:0006402330.057
regulation of cell morphogenesisGO:00226041630.056
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.055
modification dependent protein catabolic processGO:0019941780.053
Mouse
posttranscriptional regulation of gene expressionGO:00106081450.052
positive regulation of protein catabolic processGO:0045732340.052
spermatid developmentGO:0007286980.049
cellular macromolecular complex assemblyGO:00346221530.046
positive regulation of cellular protein metabolic processGO:00322701180.045
positive regulation of macromolecule metabolic processGO:00106044050.045
modification dependent macromolecule catabolic processGO:0043632790.044
Mouse
cellular amine metabolic processGO:0044106120.044
chromosome organizationGO:00512763600.044
Human
regulation of cell shapeGO:00083601130.043
catabolic processGO:00090564090.043
protein modification processGO:00362114380.042
Human
ovarian follicle cell developmentGO:00307072480.041
regionalizationGO:00030024160.040
rna localizationGO:00064031150.040
cellular protein complex assemblyGO:0043623710.040
protein modification by small protein conjugationGO:0032446790.038
Human
embryo development ending in birth or egg hatchingGO:00097921520.037
negative regulation of response to stimulusGO:00485852580.036
columnar cuboidal epithelial cell developmentGO:00020662490.036
regulation of mitotic cell cycleGO:00073461900.036
positive regulation of signal transductionGO:00099672230.036
organic acid metabolic processGO:00060821030.035
regulation of catalytic activityGO:00507901850.034
cellular ketone metabolic processGO:0042180240.034
regulation of growthGO:00400082330.033
positive regulation of nucleic acid templated transcriptionGO:19035082660.032
establishment of rna localizationGO:0051236470.032
spermatogenesisGO:00072832000.032
dna templated transcription initiationGO:0006352250.031
vesicle mediated transportGO:00161923810.031
oxoacid metabolic processGO:00434361030.030
negative regulation of mitotic cell cycleGO:00459301090.029
chaeta developmentGO:0022416970.029
regulation of organelle organizationGO:00330431960.027
positive regulation of cellular catabolic processGO:0031331950.027
peptidyl amino acid modificationGO:00181931050.027
ribonucleoprotein complex biogenesisGO:0022613310.027
agingGO:00075681430.026
small molecule metabolic processGO:00442813050.026
protein targeting to nucleusGO:0044744510.025
organic substance transportGO:00717022570.025
single organism intracellular transportGO:19025822070.024
regulation of cell developmentGO:00602842150.024
gene silencing by rnaGO:0031047570.024
regulation of cellular catabolic processGO:00313291570.023
proteasomal protein catabolic processGO:0010498590.023
Mouse
gliogenesisGO:0042063800.022
regulation of nervous system developmentGO:00519602480.022
cellular cation homeostasisGO:0030003380.022
peptidyl threonine phosphorylationGO:001810720.022
regulation of intracellular signal transductionGO:19025312360.022
positive regulation of cellular amine metabolic processGO:003324000.022
regulation of transcription from rna polymerase ii promoterGO:00063573780.021
heterocycle catabolic processGO:00467001660.021
nucleobase containing compound catabolic processGO:00346551650.021
positive regulation of signalingGO:00230562430.021
protein acetylationGO:0006473390.021
nuclear transcribed mrna catabolic processGO:0000956240.021
transcription initiation from rna polymerase ii promoterGO:0006367250.020
nucleocytoplasmic transportGO:0006913720.020
imaginal disc pattern formationGO:0007447910.020
positive regulation of cell communicationGO:00106472500.020
histone h2a acetylationGO:004396810.020
rna interferenceGO:0016246270.020
mitotic nuclear divisionGO:00070672130.020
cell growthGO:00160491080.020
response to external biotic stimulusGO:00432072930.020
regulation of protein complex assemblyGO:0043254420.019
wnt signaling pathwayGO:0016055980.019
reproductive structure developmentGO:0048608740.018
single organism biosynthetic processGO:00447112060.018
anterior posterior axis specificationGO:00099481090.018
positive regulation of nucleobase containing compound metabolic processGO:00459353320.018
protein localization to organelleGO:0033365820.018
regulation of translationGO:0006417560.018
translationGO:0006412690.018
cytoplasmic transportGO:00164821300.017
regulation of protein modification processGO:00313991120.017
g protein coupled receptor signaling pathwayGO:00071861360.017
positive regulation of response to stimulusGO:00485843230.017
regulation of proteolysisGO:0030162870.017
stem cell differentiationGO:00488631170.017
Mouse
meiotic cell cycleGO:00513211710.017
nuclear exportGO:0051168240.017
adherens junction organizationGO:0034332270.017
negative regulation of protein metabolic processGO:0051248850.016
cellular catabolic processGO:00442483720.016
Mouse
positive regulation of cellular component organizationGO:00511301560.016
cell fate determinationGO:0001709910.016
negative regulation of growthGO:0045926840.016
regulation of cellular component biogenesisGO:00440872010.016
response to hypoxiaGO:0001666530.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
autophagic cell deathGO:0048102830.015
response to lipopolysaccharideGO:003249640.015
protein modification by small protein removalGO:0070646280.015
response to radiationGO:00093141550.015
Human
positive regulation of proteolysisGO:0045862520.015
regulation of wnt signaling pathwayGO:0030111680.015
macromolecular complex assemblyGO:00650032560.015
regulation of hydrolase activityGO:0051336970.015
regulation of cell cycleGO:00517262910.014
organonitrogen compound metabolic processGO:19015643180.014
regulation of mrna 3 end processingGO:003144070.014
sex differentiationGO:0007548810.014
organelle inheritanceGO:004830820.014
negative regulation of developmental processGO:00510932010.013
Mouse
endocytosisGO:00068973100.013
purine ribonucleotide catabolic processGO:00091541090.013
protein localization to nucleusGO:0034504550.013
nucleic acid transportGO:0050657460.013
cellular protein catabolic processGO:0044257830.013
Mouse
positive regulation of hydrolase activityGO:0051345780.013
regulation of protein phosphorylationGO:0001932640.013
hematopoietic progenitor cell differentiationGO:000224410.013
positive regulation of nitrogen compound metabolic processGO:00511733540.013
larval developmentGO:00021641040.013
protein localizationGO:00081042840.012
positive regulation of macromolecule biosynthetic processGO:00105572830.012
regulation of notch signaling pathwayGO:00085931000.012
rna catabolic processGO:0006401370.012
positive regulation of protein modification processGO:0031401580.012
wound healingGO:0042060750.012
regulation of neurogenesisGO:00507671580.012
compound eye developmentGO:00487493070.012
negative regulation of cellular protein metabolic processGO:0032269850.012
defense response to other organismGO:00985422250.011
jak stat cascadeGO:0007259490.011
protein transportGO:00150311550.011
nephron epithelium developmentGO:007200930.011
response to other organismGO:00517072930.011
protein dna complex assemblyGO:0065004630.011
protein import into nucleusGO:0006606510.011
rna processingGO:00063961470.011
chromatin modificationGO:00165681470.011
Human
regulation of cellular protein catabolic processGO:1903362440.011
eggshell chorion gene amplificationGO:000730790.010
regulation of mitotic cell cycle phase transitionGO:19019901300.010
formation of a compartment boundaryGO:006028840.010
meiotic nuclear divisionGO:00071261510.010
dsrna fragmentationGO:0031050150.010
phosphorylationGO:00163102940.010
phagocytosisGO:00069092150.010
mitotic cell cycle phase transitionGO:00447721380.010
internal peptidyl lysine acetylationGO:0018393380.010

Cul-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
disease of cellular proliferationDOID:1456600.011