Drosophila melanogaster

157 known processes

sec5 (Dmel_CG8843)

CG8843 gene product from transcript CG8843-RA

(Aliases: Dmel\CG8843,Sec5p,Sec-5,CG8843,dsec5,Sec5)

sec5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pole plasm mrna localizationGO:0019094491.000
pole plasm oskar mrna localizationGO:0045451460.998
pole plasm rna localizationGO:0007316520.997
oocyte constructionGO:00073081120.992
pole plasm assemblyGO:0007315610.990
oocyte differentiationGO:00099941450.976
oocyte developmentGO:00485991240.974
oocyte anterior posterior axis specificationGO:0007314720.973
oocyte axis specificationGO:00073091080.946
tripartite regional subdivisionGO:00073511030.887
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.879
maternal determination of anterior posterior axis embryoGO:0008358740.829
developmental maturationGO:00217001720.818
blastoderm segmentationGO:00073501590.813
rna localizationGO:00064031150.799
intracellular mrna localization involved in pattern specification processGO:0060810560.794
cell maturationGO:00484691440.780
axonogenesisGO:00074092900.744
ovarian follicle cell developmentGO:00307072480.720
cytoplasm organizationGO:0007028640.712
cytoplasmic transport nurse cell to oocyteGO:0007303120.678
intracellular mrna localizationGO:0008298660.660
embryonic pattern specificationGO:00098801740.658
anterior posterior axis specificationGO:00099481090.571
anterior posterior pattern specificationGO:00099521360.563
actin cytoskeleton organizationGO:00300362060.519
border follicle cell migrationGO:00072981130.507
anterior posterior axis specification embryoGO:00085951030.506
epithelial cell migrationGO:00106311480.506
embryonic axis specificationGO:00005781070.502
axon guidanceGO:00074112330.426
germarium derived oocyte fate determinationGO:0007294260.415
single organism cellular localizationGO:19025801800.374
axon developmentGO:00615642970.357
oocyte microtubule cytoskeleton organizationGO:0016325350.348
regionalizationGO:00030024160.347
regulation of pole plasm oskar mrna localizationGO:0007317270.323
localization of cellGO:00516742570.319
cellular macromolecule catabolic processGO:00442651360.306
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.299
neuron projection guidanceGO:00974852410.297
ovarian follicle cell migrationGO:00072971210.295
compound eye morphogenesisGO:00017452490.292
sensory organ morphogenesisGO:00905962600.282
establishment of localization in cellGO:00516494020.279
eye photoreceptor cell developmentGO:0042462810.272
endocytosisGO:00068973100.268
regulation of developmental growthGO:00486381740.262
cell deathGO:00082192790.258
Worm
oocyte microtubule cytoskeleton polarizationGO:0008103220.258
columnar cuboidal epithelial cell differentiationGO:00020652560.258
epithelial cell developmentGO:00020642740.247
regulation of cellular component sizeGO:0032535980.243
axis specificationGO:00097981670.238
segmentationGO:00352822070.217
morphogenesis of an epitheliumGO:00020092760.195
regulation of multicellular organismal developmentGO:20000264140.189
regulation of anatomical structure sizeGO:00900661630.177
single organism intracellular transportGO:19025822070.165
organelle localizationGO:00516401480.163
eye morphogenesisGO:00485922600.157
compound eye developmentGO:00487493070.150
vesicle mediated transportGO:00161923810.149
rhabdomere developmentGO:0042052380.149
epithelium migrationGO:00901321480.149
protein localizationGO:00081042840.149
germarium derived egg chamber formationGO:00072931010.148
regulation of nervous system developmentGO:00519602480.147
macromolecule catabolic processGO:00090571610.131
rhabdomere membrane biogenesisGO:004531360.131
oocyte fate determinationGO:0030716270.130
positive regulation of axonogenesisGO:005077220.129
tissue morphogenesisGO:00487292970.128
ameboidal type cell migrationGO:00016671510.125
establishment or maintenance of cytoskeleton polarityGO:0030952440.124
germarium derived oocyte differentiationGO:0030706290.123
cell divisionGO:00513012480.121
protein catabolic processGO:00301631010.118
cellular macromolecule localizationGO:00707272200.115
dendrite developmentGO:00163582040.113
compound eye photoreceptor developmentGO:0042051780.112
regulation of axonogenesisGO:0050770320.107
cell migrationGO:00164772380.103
defense responseGO:00069523000.102
regulation of cell projection organizationGO:0031344920.097
plasma membrane organizationGO:0007009260.095
eye developmentGO:00016543230.091
positive regulation of signalingGO:00230562430.091
dorsal ventral pattern formationGO:00099531330.088
protein complex assemblyGO:00064612000.087
proteolysisGO:00065081920.087
photoreceptor cell differentiationGO:00465301700.087
cellular catabolic processGO:00442483720.086
molting cycleGO:0042303560.086
organonitrogen compound metabolic processGO:19015643180.084
actin filament based processGO:00300292200.082
programmed cell deathGO:00125012570.082
Worm
tissue migrationGO:00901301550.080
regulation of growthGO:00400082330.079
nucleoside metabolic processGO:00091161270.078
columnar cuboidal epithelial cell developmentGO:00020662490.077
brain developmentGO:00074201200.076
developmental growthGO:00485892800.075
cellular homeostasisGO:0019725800.075
regulation of cellular component biogenesisGO:00440872010.073
actin polymerization or depolymerizationGO:0008154310.072
regulation of behaviorGO:0050795750.070
homeostatic processGO:00425921990.069
protein modification processGO:00362114380.069
intracellular signal transductionGO:00355563000.068
cytoskeleton dependent cytokinesisGO:0061640810.068
regulation of cell developmentGO:00602842150.068
protein complex biogenesisGO:00702712010.067
actin filament organizationGO:00070151260.064
regulation of oocyte developmentGO:0060281270.062
photoreceptor cell developmentGO:0042461960.062
synapse organizationGO:00508081960.062
lipid modificationGO:0030258240.060
nucleus localizationGO:0051647340.060
positive regulation of signal transductionGO:00099672230.059
protein localization to plasma membraneGO:0072659130.058
organic substance transportGO:00717022570.058
cytoplasmic transportGO:00164821300.057
lipid metabolic processGO:00066291210.057
organic substance catabolic processGO:19015753080.057
proteolysis involved in cellular protein catabolic processGO:0051603830.056
branching morphogenesis of an epithelial tubeGO:0048754450.055
cellular component assembly involved in morphogenesisGO:00109271510.055
golgi to plasma membrane protein transportGO:004300180.055
establishment of protein localizationGO:00451841630.054
apical constrictionGO:0003383180.054
regulation of embryonic pattern specificationGO:1902875270.053
dendrite morphogenesisGO:00488131990.053
endomembrane system organizationGO:00102561190.052
establishment or maintenance of cell polarityGO:00071631670.052
compound eye photoreceptor cell differentiationGO:00017511400.051
positive regulation of axon extensionGO:004577320.051
regulation of actin filament depolymerizationGO:003083430.051
single organism catabolic processGO:00447122280.051
rna splicingGO:0008380830.051
chemical homeostasisGO:0048878920.050
regulation of cellular amino acid metabolic processGO:000652100.049
chemotaxisGO:00069352490.048
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.048
negative regulation of actin filament depolymerizationGO:003083520.047
wing disc morphogenesisGO:00074723440.046
small molecule metabolic processGO:00442813050.046
nucleus organizationGO:0006997450.046
regulation of neurogenesisGO:00507671580.045
growthGO:00400073590.045
cellular protein catabolic processGO:0044257830.044
regulation of programmed cell deathGO:00430671520.044
response to bacteriumGO:00096171980.044
regulation of actin polymerization or depolymerizationGO:0008064270.043
regulation of dendrite morphogenesisGO:0048814280.043
germ line cyst formationGO:0048134440.043
carboxylic acid metabolic processGO:0019752920.043
positive regulation of response to stimulusGO:00485843230.042
negative regulation of cellular component organizationGO:00511291080.042
actin filament polymerizationGO:0030041270.042
outflow tract morphogenesisGO:000315140.040
catabolic processGO:00090564090.040
regulation of cell differentiationGO:00455953020.040
neuroblast proliferationGO:0007405740.040
modification dependent macromolecule catabolic processGO:0043632790.039
connective tissue developmentGO:006144830.039
eye photoreceptor cell differentiationGO:00017541450.039
regulation of cell sizeGO:0008361630.039
meiotic cell cycleGO:00513211710.038
organic acid metabolic processGO:00060821030.038
ubiquitin dependent protein catabolic processGO:0006511780.038
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.038
positive regulation of developmental processGO:00510941430.037
imaginal disc derived appendage developmentGO:00487373990.037
morphogenesis of follicular epitheliumGO:0016333360.037
establishment or maintenance of bipolar cell polarityGO:0061245340.037
rna transportGO:0050658460.036
oocyte dorsal ventral axis specificationGO:0007310340.036
cellular protein complex assemblyGO:0043623710.036
modification dependent protein catabolic processGO:0019941780.036
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.036
imaginal disc derived wing morphogenesisGO:00074763370.036
guanosine containing compound catabolic processGO:1901069740.036
body morphogenesisGO:001017120.036
positive regulation of phosphorus metabolic processGO:00105621390.035
negative regulation of insulin receptor signaling pathwayGO:0046627110.035
mrna metabolic processGO:00160711240.034
regulation of gtp catabolic processGO:0033124440.034
cellular component disassemblyGO:0022411460.033
immune responseGO:00069552460.033
regulation of dna templated transcription elongationGO:0032784170.033
specification of organ identityGO:001009230.033
carbohydrate derivative metabolic processGO:19011352170.032
regulation of apoptotic processGO:00429811300.032
cellularizationGO:0007349900.032
cellular chemical homeostasisGO:0055082400.032
small gtpase mediated signal transductionGO:0007264880.031
taxisGO:00423303040.031
response to woundingGO:0009611940.031
cellular protein localizationGO:00346131600.031
positive regulation of cell developmentGO:0010720610.031
negative regulation of cell deathGO:0060548810.031
apoptotic processGO:00069151590.031
Worm
regulation of gtpase activityGO:0043087440.031
nuclear divisionGO:00002803320.030
regulation of cell morphogenesis involved in differentiationGO:0010769610.030
cellular ion homeostasisGO:0006873390.029
macromolecular complex assemblyGO:00650032560.029
male gamete generationGO:00482322010.029
cellular macromolecular complex assemblyGO:00346221530.029
response to hypoxiaGO:0001666530.029
locomotory behaviorGO:00076261760.029
rna catabolic processGO:0006401370.028
oxoacid metabolic processGO:00434361030.028
ras protein signal transductionGO:0007265880.028
phagocytosisGO:00069092150.028
deathGO:00162652840.027
Worm
single organism behaviorGO:00447083910.027
stem cell developmentGO:0048864790.027
nucleobase containing compound catabolic processGO:00346551650.027
phosphorylationGO:00163102940.027
female germ line cyst formationGO:0048135420.027
aromatic compound catabolic processGO:00194391660.027
regulation of localizationGO:00328792750.027
nucleoside phosphate catabolic processGO:19012921100.026
cilium morphogenesisGO:0060271390.026
regulation of phosphate metabolic processGO:00192202100.026
regulation of neuron projection developmentGO:0010975690.026
nucleobase containing compound transportGO:0015931560.026
establishment of nucleus localizationGO:0040023260.026
germarium derived female germ line cyst formationGO:0030727420.026
golgi vesicle transportGO:0048193270.025
negative regulation of programmed cell deathGO:0043069720.025
mesenchymal cell differentiationGO:004876210.025
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018480.025
embryonic heart tube developmentGO:0035050220.024
forebrain developmentGO:003090020.024
terminal region determinationGO:0007362250.024
eggshell formationGO:00307031050.024
establishment of organelle localizationGO:00516561220.023
regulation of golgi to plasma membrane protein transportGO:004299660.023
organic cyclic compound catabolic processGO:19013611680.023
response to organic substanceGO:00100332840.022
regulation of actin cytoskeleton organizationGO:0032956420.022
single fertilizationGO:0007338240.022
enzyme linked receptor protein signaling pathwayGO:00071671790.022
purine ribonucleoside triphosphate metabolic processGO:00092051190.022
negative regulation of protein depolymerizationGO:1901880230.022
negative regulation of protein complex disassemblyGO:0043242230.022
regulation of actin filament lengthGO:0030832270.022
regulation of axon extensionGO:003051680.021
zonula adherens assemblyGO:004518660.021
negative regulation of response to stimulusGO:00485852580.021
regulation of embryonic developmentGO:0045995680.021
epithelial cell differentiationGO:00308553220.021
apoptotic signaling pathwayGO:0097190270.021
molting cycle chitin based cuticleGO:0007591560.021
mrna processingGO:00063971040.020
negative regulation of protein polymerizationGO:003227270.020
negative regulation of signal transductionGO:00099682060.020
regulation of cellular amine metabolic processGO:003323830.020
regulation of neuron deathGO:1901214260.020
single organism biosynthetic processGO:00447112060.020
retina development in camera type eyeGO:006004140.020
phosphatidylinositol phosphorylationGO:0046854100.020
determination of adult lifespanGO:00083401370.020
protein modification by small protein conjugationGO:0032446790.020
humoral immune responseGO:00069591170.020
chitin based embryonic cuticle biosynthetic processGO:0008362160.020
appendage developmentGO:00487364010.020
muscle structure developmentGO:00610612240.020
cellular lipid metabolic processGO:0044255830.019
heterocycle catabolic processGO:00467001660.019
meiotic nuclear divisionGO:00071261510.019
regulation of synaptic growth at neuromuscular junctionGO:0008582890.019
establishment of rna localizationGO:0051236470.019
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.019
response to decreased oxygen levelsGO:0036293580.019
regulation of nucleoside metabolic processGO:0009118500.019
lateral inhibitionGO:00463312060.019
spindle assemblyGO:0051225800.019
establishment of protein localization to plasma membraneGO:009000290.018
regulation of cell deathGO:00109411730.018
guanosine containing compound metabolic processGO:1901068740.018
regulation of transportGO:00510491810.018
positive regulation of gtpase activityGO:0043547430.018
posttranscriptional regulation of gene expressionGO:00106081450.018
spermatid differentiationGO:00485151140.018
nucleocytoplasmic transportGO:0006913720.018
regulation of small gtpase mediated signal transductionGO:0051056930.018
protein polymerizationGO:0051258420.018
membrane biogenesisGO:004409180.018
regulation of catabolic processGO:00098941700.018
negative regulation of developmental processGO:00510932010.018
multi multicellular organism processGO:00447061230.017
regulation of cellular localizationGO:00603411360.017
neural precursor cell proliferationGO:0061351750.017
developmental growth involved in morphogenesisGO:0060560650.017
purine nucleotide metabolic processGO:00061631460.017
purine nucleoside metabolic processGO:00422781270.017
positive regulation of cell projection organizationGO:0031346290.017
synaptic vesicle endocytosisGO:0048488280.017
camera type eye morphogenesisGO:004859320.017
mapk cascadeGO:00001651070.017
response to biotic stimulusGO:00096072940.017
establishment of mitochondrion localizationGO:005165470.017
regulation of reproductive processGO:2000241540.017
tube developmentGO:00352952440.017
response to other organismGO:00517072930.017
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.017
lipid phosphorylationGO:0046834110.017
mesenchymal cell developmentGO:001403110.016
cellular response to decreased oxygen levelsGO:0036294300.016
stem cell differentiationGO:00488631170.016
protein transportGO:00150311550.016
glycerophospholipid metabolic processGO:0006650230.016
negative regulation of biosynthetic processGO:00098902770.016
male meiosis cytokinesisGO:0007112260.016
proteasomal protein catabolic processGO:0010498590.016
regulation of nurse cell apoptotic processGO:004547790.016
negative regulation of epithelial cell proliferationGO:005068040.016
regulation of synapse assemblyGO:0051963940.016
negative regulation of apoptotic processGO:0043066630.016
regulation of actin filament polymerizationGO:0030833250.016
stem cell proliferationGO:0072089880.016
regulation of protein polymerizationGO:0032271280.016
regulation of intracellular signal transductionGO:19025312360.016
central nervous system developmentGO:00074172010.016
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.015
regulation of circadian rhythmGO:0042752490.015
convergent extensionGO:006002620.015
positive regulation of ras gtpase activityGO:0032320360.015
mrna transportGO:0051028150.015
negative regulation of cellular metabolic processGO:00313243820.015
actin filament cappingGO:005169320.015
developmental cell growthGO:0048588520.015
gtp catabolic processGO:0006184720.015
embryo development ending in birth or egg hatchingGO:00097921520.015
Worm
regulation of phosphorylationGO:00423251470.015
gene silencing by mirnaGO:0035195220.015
regulation of phosphorus metabolic processGO:00511742100.015
regulation of cellular protein metabolic processGO:00322682430.015
cell projection assemblyGO:0030031940.015
positive regulation of neurogenesisGO:0050769410.015
spiracle morphogenesis open tracheal systemGO:0035277220.015
neuromuscular synaptic transmissionGO:0007274670.015
regulation of stress activated protein kinase signaling cascadeGO:0070302420.015
multicellular organismal agingGO:00102591400.014
regulation of autophagyGO:0010506620.014
synaptic vesicle recyclingGO:0036465280.014
mitotic cytokinesisGO:0000281500.014
positive regulation of nervous system developmentGO:0051962690.014
negative regulation of actin filament polymerizationGO:003083770.014
response to oxygen containing compoundGO:19017002000.014
carbohydrate derivative catabolic processGO:19011361180.014
bicoid mrna localizationGO:004545080.014
axon choice point recognitionGO:0016198260.014
axon cargo transportGO:0008088290.014
embryonic development via the syncytial blastodermGO:00017001480.014
anatomical structure homeostasisGO:0060249970.014
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.014
cellular ketone metabolic processGO:0042180240.014
pseudocleavage involved in syncytial blastoderm formationGO:003058990.014
regulation of alternative mrna splicing via spliceosomeGO:0000381600.014
response to external biotic stimulusGO:00432072930.014
cellular protein modification processGO:00064644380.014
organophosphate metabolic processGO:00196371950.013
imaginal disc derived appendage morphogenesisGO:00351143950.013
meiotic cytokinesisGO:0033206330.013
rna processingGO:00063961470.013
response to abiotic stimulusGO:00096283410.013
rhythmic processGO:00485111060.013
spermatid developmentGO:0007286980.013
larval developmentGO:00021641040.013
organelle assemblyGO:00709251980.013
positive regulation of transcription dna templatedGO:00458932660.013
regulation of multicellular organism growthGO:0040014400.013
protein modification by small protein conjugation or removalGO:00706471060.013
extrinsic apoptotic signaling pathwayGO:009719110.013
neuron deathGO:0070997270.013
positive regulation of multicellular organismal processGO:00512401430.013
jnk cascadeGO:0007254500.013
retina morphogenesis in camera type eyeGO:006004220.013
endocytic recyclingGO:0032456130.013
carbohydrate metabolic processGO:0005975820.013
positive regulation of developmental growthGO:0048639620.013
nuclear body organizationGO:003057560.013
liposaccharide metabolic processGO:190350980.012
intrinsic apoptotic signaling pathwayGO:0097193160.012
wnt signaling pathwayGO:0016055980.012
axis elongationGO:000340130.012
mrna splicing via spliceosomeGO:0000398730.012
regulation of protein complex disassemblyGO:0043244290.012
regulation of cell divisionGO:0051302720.012
microtubule based movementGO:0007018510.012
regulation of neuron differentiationGO:00456641030.012
positive regulation of intracellular transportGO:0032388420.012
ovarian nurse cell to oocyte transportGO:0007300270.012
cell proliferationGO:00082832990.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.012
reproductive behaviorGO:00190981220.012
rna splicing via transesterification reactionsGO:0000375730.012
scf dependent proteasomal ubiquitin dependent protein catabolic processGO:003114610.012
nucleobase containing small molecule metabolic processGO:00550861740.012
positive regulation of neurotransmitter transportGO:005159020.012
chorion containing eggshell formationGO:00073041050.012
agingGO:00075681430.012
wound healingGO:0042060750.012
positive regulation of phosphate metabolic processGO:00459371390.012
post embryonic appendage morphogenesisGO:00351203850.012
muscle organ developmentGO:00075171270.012
pronuclear migrationGO:003504640.011
developmental programmed cell deathGO:00106231380.011
synaptic vesicle localizationGO:0097479530.011
gtp metabolic processGO:0046039720.011
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.011
glycerolipid metabolic processGO:0046486340.011
mrna catabolic processGO:0006402330.011
epidermis developmentGO:0008544650.011
meiotic cell cycle processGO:19030461320.011
regulation of cell maturationGO:1903429270.011
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:003072260.011
multi organism behaviorGO:00517051750.011
nitrogen compound transportGO:0071705850.011
intracellular transportGO:00469072280.011
axon extensionGO:0048675320.011
cytokinesisGO:0000910900.011
learning or memoryGO:00076111410.011
cytoskeleton dependent intracellular transportGO:0030705440.011
regulation of cellular ketone metabolic processGO:001056530.011
regulation of cell cycleGO:00517262910.011
positive regulation of cell communicationGO:00106472500.011
multi organism reproductive behaviorGO:00447051210.011
protein complex disassemblyGO:0043241360.011
protein ubiquitinationGO:0016567700.011
cellular amine metabolic processGO:0044106120.011
regulation of mitotic cell cycleGO:00073461900.011
instar larval developmentGO:0002168550.011
multicellular organismal homeostasisGO:0048871410.011
regulation of epithelial cell differentiationGO:003085640.011
establishment of cell polarityGO:0030010400.010
sperm individualizationGO:0007291480.010
determination of ventral identityGO:004826410.010
regulation of anatomical structure morphogenesisGO:00226032420.010
peptidyl amino acid modificationGO:00181931050.010
negative regulation of cytoskeleton organizationGO:0051494300.010
cellular protein complex disassemblyGO:0043624350.010
cell motilityGO:00488702510.010
phospholipid metabolic processGO:0006644230.010
regulation of organelle organizationGO:00330431960.010
eye antennal disc developmentGO:0035214600.010
response to oxidative stressGO:0006979860.010
cytoplasmic sequestering of proteinGO:005122040.010

sec5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.022
disease of cellular proliferationDOID:1456600.022
cancerDOID:16200.022
disease of anatomical entityDOID:700.021
cardiovascular system diseaseDOID:128700.021
vascular diseaseDOID:17800.012
artery diseaseDOID:005082800.012
myopathyDOID:42300.010
muscular diseaseDOID:008000000.010
muscular dystrophyDOID:988400.010
limb girdle muscular dystrophyDOID:1172400.010
musculoskeletal system diseaseDOID:1700.010
muscle tissue diseaseDOID:6600.010