IMP: Integrative Multi-species Prediction

Drosophila melanogaster

88 known processes

Fps85D (Dmel_CG8874)

Fps oncogene analog

(Aliases: Dm FPS,CG8874,fps,Dfer,dfer,DFer,fps85D,HD-179,dfps,fer,dfps 85D,FER,dfps85D,FPS,Fer,dFer,DFER,Dfps,Dmel\CG8874,DmHD-179)

Entrez: 41118
FLYBASE: FBgn0000723
UniProtKB: P18106

Process Predictions
Disease Predictions

Fps85D biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
imaginal disc derived appendage development	GO:0048737	399	0.462
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.401
ameboidal type cell migration	GO:0001667	151	0.377	Mouse
imaginal disc derived wing morphogenesis	GO:0007476	337	0.364
growth	GO:0040007	359	0.337
respiratory system development	GO:0060541	213	0.320
post embryonic appendage morphogenesis	GO:0035120	385	0.316
epithelial cell migration	GO:0010631	148	0.315
appendage morphogenesis	GO:0035107	397	0.273
immune system process	GO:0002376	347	0.254	Human Mouse
response to temperature stimulus	GO:0009266	106	0.246
axon development	GO:0061564	297	0.231
developmental growth	GO:0048589	280	0.226
defense response	GO:0006952	300	0.215
appendage development	GO:0048736	401	0.200
axonogenesis	GO:0007409	290	0.194
carbohydrate derivative metabolic process	GO:1901135	217	0.191
regulation of embryonic development	GO:0045995	68	0.182
tissue migration	GO:0090130	155	0.164
positive regulation of macromolecule metabolic process	GO:0010604	405	0.157
vesicle mediated transport	GO:0016192	381	0.152	Human Worm
regulation of growth	GO:0040008	233	0.151
intracellular signal transduction	GO:0035556	300	0.150	Human
negative regulation of biosynthetic process	GO:0009890	277	0.145
organonitrogen compound metabolic process	GO:1901564	318	0.144
localization of cell	GO:0051674	257	0.142	Human Mouse
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.142
wing disc morphogenesis	GO:0007472	344	0.141
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.139
single organism biosynthetic process	GO:0044711	206	0.135
epithelium migration	GO:0090132	148	0.134
catabolic process	GO:0009056	409	0.120
response to trehalose	GO:0010353	3	0.120
negative regulation of cellular biosynthetic process	GO:0031327	277	0.118
microtubule organizing center organization	GO:0031023	168	0.116	Mouse
epithelial cell differentiation	GO:0030855	322	0.116	Worm
lateral inhibition	GO:0046331	206	0.112
regulation of developmental growth	GO:0048638	174	0.109
negative regulation of cellular metabolic process	GO:0031324	382	0.109
organic cyclic compound catabolic process	GO:1901361	168	0.106
nucleoside phosphate metabolic process	GO:0006753	162	0.106
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.103
organelle assembly	GO:0070925	198	0.101
positive regulation of gene expression	GO:0010628	290	0.098
protein modification process	GO:0036211	438	0.094	Human Mouse Worm
negative regulation of growth	GO:0045926	84	0.093
small molecule metabolic process	GO:0044281	305	0.093
imaginal disc pattern formation	GO:0007447	91	0.092
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.091
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.091
exocytosis	GO:0006887	28	0.088	Human
organelle fission	GO:0048285	340	0.087
cellular protein modification process	GO:0006464	438	0.084	Human Mouse Worm
cell migration	GO:0016477	238	0.083	Human Mouse
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.082
macromolecule catabolic process	GO:0009057	161	0.082
phosphorylation	GO:0016310	294	0.081	Human Mouse Worm
amine metabolic process	GO:0009308	12	0.081
establishment or maintenance of cell polarity	GO:0007163	167	0.079
single organism cellular localization	GO:1902580	180	0.079	Human
negative regulation of gene expression	GO:0010629	387	0.079
regionalization	GO:0003002	416	0.078
negative regulation of developmental process	GO:0051093	201	0.077
cellular response to chemical stimulus	GO:0070887	199	0.076	Human Mouse
cellular nitrogen compound catabolic process	GO:0044270	165	0.075
chromosome organization	GO:0051276	360	0.074
positive regulation of rna biosynthetic process	GO:1902680	266	0.073
acetylcholine catabolic process	GO:0006581	1	0.070
single organism behavior	GO:0044708	391	0.069
cellular response to ethanol	GO:0071361	4	0.068
ovarian follicle cell migration	GO:0007297	121	0.068
purine containing compound metabolic process	GO:0072521	155	0.067
positive regulation of cellular biosynthetic process	GO:0031328	316	0.066
negative regulation of response to stimulus	GO:0048585	258	0.066	Mouse
endomembrane system organization	GO:0010256	119	0.066
response to organic substance	GO:0010033	284	0.065	Human Mouse
cellular response to organic substance	GO:0071310	132	0.065	Human Mouse
positive regulation of developmental process	GO:0051094	143	0.063	Human
positive regulation of rna metabolic process	GO:0051254	271	0.063
ras protein signal transduction	GO:0007265	88	0.062
innate immune response	GO:0045087	144	0.062
centrosome organization	GO:0051297	163	0.062	Mouse
negative regulation of multicellular organismal process	GO:0051241	142	0.061
columnar cuboidal epithelial cell development	GO:0002066	249	0.061
nucleobase containing small molecule metabolic process	GO:0055086	174	0.060
negative regulation of rna biosynthetic process	GO:1902679	240	0.059
ribose phosphate metabolic process	GO:0019693	145	0.059
positive regulation of transcription dna templated	GO:0045893	266	0.058
oocyte construction	GO:0007308	112	0.057
cell adhesion	GO:0007155	136	0.057	Human Mouse Worm
negative regulation of transcription dna templated	GO:0045892	237	0.057
organophosphate metabolic process	GO:0019637	195	0.056
cellular catabolic process	GO:0044248	372	0.056
developmental growth involved in morphogenesis	GO:0060560	65	0.056
cell projection assembly	GO:0030031	94	0.055	Human
organonitrogen compound catabolic process	GO:1901565	128	0.054
regulation of multicellular organismal development	GO:2000026	414	0.054
chaeta development	GO:0022416	97	0.053
regulation of intracellular signal transduction	GO:1902531	236	0.051
secretion by cell	GO:0032940	101	0.051	Human
purine ribonucleotide metabolic process	GO:0009150	145	0.051
regulation of epithelial cell differentiation	GO:0030856	4	0.051	Worm
sensory organ morphogenesis	GO:0090596	260	0.051
regulation of cell differentiation	GO:0045595	302	0.051	Human Worm
nucleobase containing compound catabolic process	GO:0034655	165	0.050
skin development	GO:0043588	65	0.049	Worm
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.049
ovarian follicle cell development	GO:0030707	248	0.049
purine nucleotide metabolic process	GO:0006163	146	0.049
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.048	Human Mouse
axon guidance	GO:0007411	233	0.048
nuclear division	GO:0000280	332	0.048
multicellular organismal aging	GO:0010259	140	0.048
positive regulation of cellular component organization	GO:0051130	156	0.047	Human
positive regulation of biosynthetic process	GO:0009891	316	0.047
male gamete generation	GO:0048232	201	0.045	Worm
synaptic transmission	GO:0007268	288	0.044
cellular amine metabolic process	GO:0044106	12	0.044
purine nucleotide catabolic process	GO:0006195	109	0.043
glycosyl compound catabolic process	GO:1901658	112	0.043
cytoplasm organization	GO:0007028	64	0.043
aromatic compound catabolic process	GO:0019439	166	0.042
establishment of localization in cell	GO:0051649	402	0.042	Human
leg disc development	GO:0035218	92	0.042
developmental maturation	GO:0021700	172	0.042
neurological system process	GO:0050877	358	0.042
response to abiotic stimulus	GO:0009628	341	0.041
regulation of catabolic process	GO:0009894	170	0.041
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.041
oocyte axis specification	GO:0007309	108	0.041
spermatogenesis	GO:0007283	200	0.040	Worm
response to oxygen containing compound	GO:1901700	200	0.040	Mouse
border follicle cell migration	GO:0007298	113	0.040
negative regulation of developmental growth	GO:0048640	64	0.039
cell death	GO:0008219	279	0.039
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.039
posttranscriptional regulation of gene expression	GO:0010608	145	0.039
nucleotide catabolic process	GO:0009166	109	0.039
small gtpase mediated signal transduction	GO:0007264	88	0.038
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.038	Human Mouse
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.038
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.037
cell substrate adhesion	GO:0031589	10	0.037	Mouse
heterocycle catabolic process	GO:0046700	166	0.036
pigment metabolic process	GO:0042440	84	0.036
positive regulation of phosphate metabolic process	GO:0045937	139	0.036
taxis	GO:0042330	304	0.036
positive regulation of cell communication	GO:0010647	250	0.036
cellular macromolecule localization	GO:0070727	220	0.036
cellular protein localization	GO:0034613	160	0.035
purine ribonucleoside catabolic process	GO:0046130	112	0.035
tripartite regional subdivision	GO:0007351	103	0.035
ribonucleotide metabolic process	GO:0009259	145	0.035
wing disc pattern formation	GO:0035222	66	0.035
regulation of phosphorus metabolic process	GO:0051174	210	0.035	Mouse
carboxylic acid metabolic process	GO:0019752	92	0.034
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	38	0.034
mitotic nuclear division	GO:0007067	213	0.034
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.034
cellular macromolecule catabolic process	GO:0044265	136	0.034
compound eye morphogenesis	GO:0001745	249	0.034
positive regulation of response to stimulus	GO:0048584	323	0.034
oocyte development	GO:0048599	124	0.034
transcription from rna polymerase ii promoter	GO:0006366	368	0.033
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.033
cellular ketone metabolic process	GO:0042180	24	0.033
negative regulation of rna metabolic process	GO:0051253	251	0.033
positive regulation of signaling	GO:0023056	243	0.032
compound eye development	GO:0048749	307	0.032
single organism catabolic process	GO:0044712	228	0.032
dorsal ventral pattern formation	GO:0009953	133	0.032
regulation of cellular amine metabolic process	GO:0033238	3	0.032
oxoacid metabolic process	GO:0043436	103	0.032
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.032
cytoskeleton dependent intracellular transport	GO:0030705	44	0.032
regulation of multi organism process	GO:0043900	131	0.032
purine containing compound catabolic process	GO:0072523	112	0.032
cellular amino acid metabolic process	GO:0006520	61	0.031
nucleotide metabolic process	GO:0009117	161	0.031
tube morphogenesis	GO:0035239	191	0.031
negative regulation of signaling	GO:0023057	219	0.030
protein complex biogenesis	GO:0070271	201	0.030	Human
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.030
oxidoreduction coenzyme metabolic process	GO:0006733	2	0.030
negative regulation of cell communication	GO:0010648	223	0.030
regulation of cell cycle	GO:0051726	291	0.029
detection of stimulus	GO:0051606	156	0.029
regulation of cellular protein metabolic process	GO:0032268	243	0.029	Mouse
oocyte anterior posterior axis specification	GO:0007314	72	0.029
cell proliferation	GO:0008283	299	0.029	Human Worm
associative learning	GO:0008306	65	0.028
regulation of anatomical structure morphogenesis	GO:0022603	242	0.028
protein localization	GO:0008104	284	0.028	Worm
axon extension	GO:0048675	32	0.027
regulation of cell development	GO:0060284	215	0.027	Human
kidney development	GO:0001822	3	0.027
chemotaxis	GO:0006935	249	0.027
body morphogenesis	GO:0010171	2	0.027	Worm
intracellular mrna localization	GO:0008298	66	0.027
eye morphogenesis	GO:0048592	260	0.027
purine nucleoside metabolic process	GO:0042278	127	0.027
intracellular mrna localization involved in pattern specification process	GO:0060810	56	0.027
organonitrogen compound biosynthetic process	GO:1901566	117	0.027
golgi vesicle transport	GO:0048193	27	0.026
positive regulation of phosphorus metabolic process	GO:0010562	139	0.026
protein modification by small protein conjugation or removal	GO:0070647	106	0.026
secretion	GO:0046903	109	0.026	Human
muscle organ development	GO:0007517	127	0.026
locomotory behavior	GO:0007626	176	0.026
chaeta morphogenesis	GO:0008407	42	0.026
carbohydrate derivative biosynthetic process	GO:1901137	85	0.026
detection of chemical stimulus involved in sensory perception	GO:0050907	75	0.026
negative regulation of cell proliferation	GO:0008285	69	0.026
ribonucleotide catabolic process	GO:0009261	109	0.025
regulation of localization	GO:0032879	275	0.025	Human Mouse Worm
organic substance catabolic process	GO:1901575	308	0.025
membrane organization	GO:0061024	112	0.025
molting cycle chitin based cuticle	GO:0007591	56	0.025
pole plasm mrna localization	GO:0019094	49	0.025
anterior posterior pattern specification	GO:0009952	136	0.025
exocrine system development	GO:0035272	162	0.025
proteolysis	GO:0006508	192	0.024
steroid catabolic process	GO:0006706	1	0.024
purine ribonucleotide catabolic process	GO:0009154	109	0.024
response to nutrient levels	GO:0031667	114	0.024
determination of adult lifespan	GO:0008340	137	0.024
organophosphate catabolic process	GO:0046434	112	0.024
larval development	GO:0002164	104	0.024
circadian rhythm	GO:0007623	105	0.024
nucleoside metabolic process	GO:0009116	127	0.024
death	GO:0016265	284	0.023
rhythmic process	GO:0048511	106	0.023
rna localization	GO:0006403	115	0.023
regulation of cellular ketone metabolic process	GO:0010565	3	0.023
regulation of cell death	GO:0010941	173	0.023
regulation of reproductive process	GO:2000241	54	0.023
hindbrain development	GO:0030902	2	0.023
cell motility	GO:0048870	251	0.023	Human Mouse
negative regulation of signal transduction	GO:0009968	206	0.022
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.022
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.022
organic hydroxy compound metabolic process	GO:1901615	83	0.022
nucleoside triphosphate catabolic process	GO:0009143	108	0.022
purine nucleoside catabolic process	GO:0006152	112	0.021
learning or memory	GO:0007611	141	0.021
meiotic cell cycle	GO:0051321	171	0.021
establishment of protein localization	GO:0045184	163	0.021
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.021
regulation of molecular function	GO:0065009	217	0.021	Human
cognition	GO:0050890	141	0.021
response to biotic stimulus	GO:0009607	294	0.021	Mouse
gland morphogenesis	GO:0022612	145	0.021
notch signaling pathway	GO:0007219	120	0.021
molting cycle	GO:0042303	56	0.020
intracellular mrna localization involved in anterior posterior axis specification	GO:0060811	53	0.020
learning	GO:0007612	75	0.020
negative regulation of nervous system development	GO:0051961	92	0.020
dorsal ventral pattern formation imaginal disc	GO:0007450	51	0.020
aging	GO:0007568	143	0.020
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.020
microtubule based movement	GO:0007018	51	0.020
regulation of ras protein signal transduction	GO:0046578	93	0.020
mitochondrion organization	GO:0007005	65	0.020
imaginal disc derived wing hair organization	GO:0035317	45	0.020
guanosine containing compound catabolic process	GO:1901069	74	0.020
salivary gland morphogenesis	GO:0007435	145	0.020
chromosome segregation	GO:0007059	157	0.020
regulation of cell shape	GO:0008360	113	0.020
detection of stimulus involved in sensory perception	GO:0050906	92	0.019
asymmetric protein localization	GO:0008105	33	0.019
protein secretion	GO:0009306	45	0.019
oocyte differentiation	GO:0009994	145	0.019
gliogenesis	GO:0042063	80	0.019
response to endogenous stimulus	GO:0009719	119	0.019	Mouse
axis specification	GO:0009798	167	0.019
regulation of mitotic cell cycle	GO:0007346	190	0.019
epithelial cell development	GO:0002064	274	0.019
eye development	GO:0001654	323	0.019
nucleoside catabolic process	GO:0009164	112	0.019
regulation of cellular localization	GO:0060341	136	0.019	Human
anterior posterior axis specification	GO:0009948	109	0.019
cellular component assembly involved in morphogenesis	GO:0010927	151	0.019
organic substance transport	GO:0071702	257	0.018
organelle membrane fusion	GO:0090174	16	0.018
hair cell differentiation	GO:0035315	47	0.018
wing disc dorsal ventral pattern formation	GO:0048190	47	0.018
ethanolamine containing compound metabolic process	GO:0042439	4	0.018
epidermis development	GO:0008544	65	0.018	Worm
negative regulation of cell cycle phase transition	GO:1901988	103	0.018
response to bacterium	GO:0009617	198	0.018	Mouse
purine ribonucleoside metabolic process	GO:0046128	127	0.018
single organism membrane organization	GO:0044802	93	0.018
memory	GO:0007613	94	0.018
pyridine nucleotide metabolic process	GO:0019362	2	0.018
regulation of cellular component biogenesis	GO:0044087	201	0.018	Human
tissue morphogenesis	GO:0048729	297	0.018
wound healing	GO:0042060	75	0.018
digestive tract morphogenesis	GO:0048546	127	0.018
phagocytosis	GO:0006909	215	0.017
regulation of anatomical structure size	GO:0090066	163	0.017	Human
protein localization to organelle	GO:0033365	82	0.017
regulation of bmp signaling pathway	GO:0030510	23	0.017
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.017
positive regulation of multicellular organismal process	GO:0051240	143	0.017	Human
regulation of cell proliferation	GO:0042127	163	0.017	Human Worm
regulation of hydrolase activity	GO:0051336	97	0.017
carbohydrate derivative catabolic process	GO:1901136	118	0.017
trachea development	GO:0060438	29	0.017
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.017
negative regulation of intracellular signal transduction	GO:1902532	57	0.017
positive regulation of molecular function	GO:0044093	136	0.017	Human
regulation of nucleotide metabolic process	GO:0006140	62	0.017
organic acid metabolic process	GO:0006082	103	0.017
tube development	GO:0035295	244	0.017
chemosensory behavior	GO:0007635	106	0.017
mating	GO:0007618	120	0.016
nitrogen compound transport	GO:0071705	85	0.016
biological adhesion	GO:0022610	138	0.016	Human Mouse Worm
ribonucleoside catabolic process	GO:0042454	112	0.016
multi organism behavior	GO:0051705	175	0.016
embryonic pattern specification	GO:0009880	174	0.016
response to organonitrogen compound	GO:0010243	75	0.016	Mouse
pole plasm assembly	GO:0007315	61	0.016
mrna processing	GO:0006397	104	0.016
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.016
histone modification	GO:0016570	106	0.016
positive regulation of cellular protein metabolic process	GO:0032270	118	0.016
forebrain development	GO:0030900	2	0.016
regulation of multicellular organism growth	GO:0040014	40	0.016
positive regulation of signal transduction	GO:0009967	223	0.016
protein localization to plasma membrane	GO:0072659	13	0.016
positive regulation of nucleotide catabolic process	GO:0030813	46	0.016
purine ribonucleotide biosynthetic process	GO:0009152	28	0.015
response to nitrogen compound	GO:1901698	90	0.015	Mouse
actin filament organization	GO:0007015	126	0.015
regulation of immune response	GO:0050776	118	0.015	Human Mouse
regulation of purine nucleotide metabolic process	GO:1900542	62	0.015
positive regulation of secretion by cell	GO:1903532	20	0.015
defense response to other organism	GO:0098542	225	0.015
negative regulation of cell differentiation	GO:0045596	143	0.015
protein ubiquitination	GO:0016567	70	0.015
endocytosis	GO:0006897	310	0.015	Worm
positive regulation of cell motility	GO:2000147	3	0.015	Human
digestive system development	GO:0055123	149	0.015
defense response to bacterium	GO:0042742	178	0.015
programmed cell death	GO:0012501	257	0.015
cardiovascular system development	GO:0072358	82	0.015
protein processing	GO:0016485	68	0.015
regulation of programmed cell death	GO:0043067	152	0.015
regulation of cellular catabolic process	GO:0031329	157	0.015
nucleoside phosphate catabolic process	GO:1901292	110	0.014
cell cell junction organization	GO:0045216	55	0.014
microtubule based transport	GO:0010970	42	0.014
non sensory hair organization	GO:0035316	47	0.014
actin cytoskeleton organization	GO:0030036	206	0.014
cell division	GO:0051301	248	0.014
neuromuscular junction development	GO:0007528	149	0.014
organophosphate biosynthetic process	GO:0090407	46	0.014
regulation of apoptotic process	GO:0042981	130	0.014
regulation of notch signaling pathway	GO:0008593	100	0.014
leg disc morphogenesis	GO:0007478	80	0.014
dna metabolic process	GO:0006259	227	0.014
negative regulation of mitotic cell cycle	GO:0045930	109	0.014
regulation of mrna processing	GO:0050684	71	0.014
dendrite morphogenesis	GO:0048813	199	0.014
cell fate specification	GO:0001708	71	0.014
nucleoside phosphate biosynthetic process	GO:1901293	34	0.014
spermatid differentiation	GO:0048515	114	0.013	Worm
glial cell differentiation	GO:0010001	35	0.013
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.013
regulation of cellular component movement	GO:0051270	42	0.013	Human Mouse
regulation of protein metabolic process	GO:0051246	256	0.013	Mouse
centrosome cycle	GO:0007098	137	0.013
compound eye photoreceptor development	GO:0042051	78	0.013
olfactory behavior	GO:0042048	97	0.013
tissue homeostasis	GO:0001894	36	0.013
multicellular organismal homeostasis	GO:0048871	41	0.013
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.013	Human
instar larval development	GO:0002168	55	0.013
adult locomotory behavior	GO:0008344	76	0.013
imaginal disc derived leg joint morphogenesis	GO:0016348	15	0.013
glycosyl compound metabolic process	GO:1901657	127	0.013
positive regulation of organelle organization	GO:0010638	65	0.013	Human
embryo development ending in birth or egg hatching	GO:0009792	152	0.013
nucleoside triphosphate metabolic process	GO:0009141	120	0.013
anterior posterior axis specification embryo	GO:0008595	103	0.013
response to external biotic stimulus	GO:0043207	293	0.013	Mouse
filopodium assembly	GO:0046847	33	0.013
photoreceptor cell differentiation	GO:0046530	170	0.013
response to heat	GO:0009408	63	0.013
vesicle localization	GO:0051648	55	0.013
immune response	GO:0006955	246	0.013	Human Mouse
negative regulation of cell death	GO:0060548	81	0.012
regulation of neurological system process	GO:0031644	8	0.012
positive regulation of growth	GO:0045927	75	0.012
synaptic growth at neuromuscular junction	GO:0051124	119	0.012
regulation of gene silencing	GO:0060968	63	0.012
regulation of mrna metabolic process	GO:1903311	72	0.012
epidermal cell differentiation	GO:0009913	51	0.012	Worm
proteasomal protein catabolic process	GO:0010498	59	0.012
telencephalon development	GO:0021537	2	0.012
golgi organization	GO:0007030	66	0.012
chromatin silencing	GO:0006342	76	0.012
small molecule biosynthetic process	GO:0044283	37	0.012
cell cycle phase transition	GO:0044770	140	0.012
cell fate determination	GO:0001709	91	0.012
salivary gland development	GO:0007431	162	0.012
macromolecular complex assembly	GO:0065003	256	0.012	Human
embryonic axis specification	GO:0000578	107	0.012
regulation of nucleoside metabolic process	GO:0009118	50	0.011
protein transport	GO:0015031	155	0.011
regulation of immune system process	GO:0002682	176	0.011	Human Mouse
organelle localization	GO:0051640	148	0.011	Human
stem cell proliferation	GO:0072089	88	0.011
developmental programmed cell death	GO:0010623	138	0.011
negative regulation of cell development	GO:0010721	62	0.011
cell junction organization	GO:0034330	57	0.011
cellular response to oxygen containing compound	GO:1901701	79	0.011	Mouse
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.011
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.011
regulation of epidermal cell differentiation	GO:0045604	3	0.011	Worm
positive regulation of cellular amine metabolic process	GO:0033240	0	0.011
developmental cell growth	GO:0048588	52	0.011
protein catabolic process	GO:0030163	101	0.011
axon cargo transport	GO:0008088	29	0.011
pole plasm rna localization	GO:0007316	52	0.011
intracellular transport	GO:0046907	228	0.011	Human
imaginal disc derived wing vein morphogenesis	GO:0008586	44	0.011
regulation of translation	GO:0006417	56	0.011
maintenance of cell polarity	GO:0030011	18	0.011
kidney morphogenesis	GO:0060993	3	0.011
ubiquitin dependent protein catabolic process	GO:0006511	78	0.011
neuron projection guidance	GO:0097485	241	0.011
imaginal disc derived leg morphogenesis	GO:0007480	80	0.010
g protein coupled receptor signaling pathway	GO:0007186	136	0.010
neuron projection extension	GO:1990138	32	0.010
regulation of response to stress	GO:0080134	200	0.010
response to lipid	GO:0033993	38	0.010	Mouse
response to radiation	GO:0009314	155	0.010
regulation of tube architecture open tracheal system	GO:0035152	68	0.010
cellular response to dna damage stimulus	GO:0006974	223	0.010
positive regulation of cellular catabolic process	GO:0031331	95	0.010
bmp signaling pathway	GO:0030509	27	0.010
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.010
mitotic cell cycle phase transition	GO:0044772	138	0.010
regulation of proteolysis	GO:0030162	87	0.010
translation	GO:0006412	69	0.010
smoothened signaling pathway	GO:0007224	49	0.010
regulation of locomotion	GO:0040012	42	0.010	Human Mouse
spermatid development	GO:0007286	98	0.010	Worm
connective tissue development	GO:0061448	3	0.010
sex differentiation	GO:0007548	81	0.010	Worm
eye pigment metabolic process	GO:0042441	33	0.010

Fps85D disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.191
nervous system disease	DOID:863	0.021
disease of cellular proliferation	DOID:14566	0.017
organ system cancer	DOID:0050686	0.017
cancer	DOID:162	0.017
inherited metabolic disorder	DOID:655	0.014
disease of metabolism	DOID:0014667	0.014
cardiovascular system disease	DOID:1287	0.011
musculoskeletal system disease	DOID:17	0.010

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