Drosophila melanogaster

127 known processes

exd (Dmel_CG8933)

extradenticle

(Aliases: EXD,anon-EST:fe1H3,td48,DExd,Exd,CG8933,l(1)IV,Dmel\CG8933,Dm-EXD,Dpbx,Pbx1)

exd biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of cellular biosynthetic processGO:00313283161.000
positive regulation of macromolecule biosynthetic processGO:00105572830.961
regulation of transcription from rna polymerase ii promoterGO:00063573780.958
positive regulation of nucleic acid templated transcriptionGO:19035082660.944
positive regulation of transcription dna templatedGO:00458932660.917
positive regulation of biosynthetic processGO:00098913160.911
eye morphogenesisGO:00485922600.824
Zebrafish
negative regulation of developmental processGO:00510932010.796
Mouse Worm
regulation of cell differentiationGO:00455953020.787
columnar cuboidal epithelial cell developmentGO:00020662490.747
positive regulation of macromolecule metabolic processGO:00106044050.742
positive regulation of gene expressionGO:00106282900.724
peripheral nervous system developmentGO:0007422520.722
negative regulation of nucleobase containing compound metabolic processGO:00459342610.657
positive regulation of nucleobase containing compound metabolic processGO:00459353320.654
positive regulation of protein metabolic processGO:00512471280.627
sensory organ morphogenesisGO:00905962600.614
Zebrafish
negative regulation of rna biosynthetic processGO:19026792400.606
imaginal disc derived appendage developmentGO:00487373990.606
appendage morphogenesisGO:00351073970.554
Mouse
sex differentiationGO:0007548810.527
negative regulation of gene expressionGO:00106293870.486
chromosome organizationGO:00512763600.468
larval developmentGO:00021641040.433
Worm
multi organism reproductive behaviorGO:00447051210.431
Worm
negative regulation of nucleic acid templated transcriptionGO:19035072400.413
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.396
eye developmentGO:00016543230.386
negative regulation of cellular biosynthetic processGO:00313272770.384
transcription from rna polymerase ii promoterGO:00063663680.357
negative regulation of rna metabolic processGO:00512532510.325
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.324
chemotaxisGO:00069352490.311
Zebrafish
negative regulation of macromolecule biosynthetic processGO:00105582700.285
phagocytosisGO:00069092150.274
positive regulation of rna biosynthetic processGO:19026802660.272
multicellular organismal reproductive behaviorGO:00330571100.258
Worm
synapse assemblyGO:00074161430.255
positive regulation of rna metabolic processGO:00512542710.240
chromatin organizationGO:00063252070.238
positive regulation of nitrogen compound metabolic processGO:00511733540.234
segmentationGO:00352822070.223
growthGO:00400073590.204
single organism cellular localizationGO:19025801800.203
lipid storageGO:0019915380.200
Worm
developmental growthGO:00485892800.192
muscle structure developmentGO:00610612240.187
stem cell differentiationGO:00488631170.171
Zebrafish
cellular macromolecule localizationGO:00707272200.171
cellular response to dna damage stimulusGO:00069742230.170
regulation of developmental growthGO:00486381740.162
spermatogenesisGO:00072832000.159
male gamete generationGO:00482322010.154
negative regulation of biosynthetic processGO:00098902770.151
neuron projection guidanceGO:00974852410.151
Zebrafish
multi multicellular organism processGO:00447061230.150
Worm
positive regulation of growthGO:0045927750.150
eye antennal disc developmentGO:0035214600.145
cell proliferationGO:00082832990.142
Mouse
imaginal disc derived wing morphogenesisGO:00074763370.137
stem cell maintenanceGO:0019827670.136
compound eye developmentGO:00487493070.126
muscle organ developmentGO:00075171270.125
Zebrafish
negative regulation of cellular metabolic processGO:00313243820.116
regulation of cell cycle processGO:00105641810.114
Mouse
epithelial cell differentiationGO:00308553220.112
axon guidanceGO:00074112330.112
Zebrafish
negative regulation of transcription dna templatedGO:00458922370.110
dna templated transcription initiationGO:0006352250.109
endocytosisGO:00068973100.105
Worm
cell cycle phase transitionGO:00447701400.102
Mouse
regulation of growthGO:00400082330.101
response to virusGO:0009615280.101
stem cell developmentGO:0048864790.101
Zebrafish
cellular macromolecular complex assemblyGO:00346221530.098
single organism intracellular transportGO:19025822070.097
imaginal disc derived appendage morphogenesisGO:00351143950.096
gliogenesisGO:0042063800.096
notch signaling pathwayGO:00072191200.096
cell cell signaling involved in cell fate commitmentGO:00451682100.094
multicellular organism growthGO:0035264460.094
regulation of multicellular organism growthGO:0040014400.093
nephron tubule morphogenesisGO:007207830.093
Mouse
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.092
regulation of synaptic growth at neuromuscular junctionGO:0008582890.087
regulation of phosphate metabolic processGO:00192202100.085
localization of cellGO:00516742570.084
Zebrafish Worm
hindbrain developmentGO:003090220.083
Zebrafish
dendrite developmentGO:00163582040.083
establishment of localization in cellGO:00516494020.083
head developmentGO:00603221350.080
embryo development ending in birth or egg hatchingGO:00097921520.080
Zebrafish Mouse Worm
regulation of imaginal disc growthGO:0045570260.079
digestive tract morphogenesisGO:00485461270.076
Worm
negative regulation of gtpase activityGO:003426010.074
response to woundingGO:0009611940.073
peptidyl serine phosphorylationGO:001810570.073
regulation of cellular component biogenesisGO:00440872010.071
axon developmentGO:00615642970.069
Zebrafish
synaptic growth at neuromuscular junctionGO:00511241190.068
nephron epithelium developmentGO:007200930.068
Mouse
muscle tissue developmentGO:0060537300.067
Zebrafish
positive regulation of histone h3 k4 methylationGO:005157110.067
cell motilityGO:00488702510.063
Zebrafish Worm
reproductive system developmentGO:0061458740.063
ovipositionGO:0018991190.061
Worm
columnar cuboidal epithelial cell differentiationGO:00020652560.059
regulation of defense responseGO:00313471020.059
hemocyte differentiationGO:0042386380.059
wing disc morphogenesisGO:00074723440.058
wound healingGO:0042060750.058
positive regulation of developmental growthGO:0048639620.057
regulation of programmed cell deathGO:00430671520.056
positive regulation of phosphate metabolic processGO:00459371390.053
cell fate specificationGO:0001708710.052
compound eye morphogenesisGO:00017452490.050
regulation of phosphorus metabolic processGO:00511742100.049
negative regulation of nitrogen compound metabolic processGO:00511722650.049
positive regulation of viral processGO:004852420.048
oocyte morphogenesisGO:004860130.048
cell divisionGO:00513012480.047
Worm
renal system developmentGO:0072001720.047
Mouse
multi organism behaviorGO:00517051750.045
Worm
histone modificationGO:00165701060.043
programmed cell deathGO:00125012570.043
negative regulation of protein secretionGO:005070920.043
cell deathGO:00082192790.043
positive regulation of cellular protein metabolic processGO:00322701180.042
male sex differentiationGO:0046661250.040
negative regulation of cell cycle g1 s phase transitionGO:1902807130.040
negative regulation of cell differentiationGO:00455961430.039
Mouse
small molecule metabolic processGO:00442813050.039
macromolecular complex assemblyGO:00650032560.038
cell adhesionGO:00071551360.037
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encodedGO:000807110.037
reproductive structure developmentGO:0048608740.037
anterior head segmentationGO:003528830.037
mitotic spindle organizationGO:00070522200.037
body morphogenesisGO:001017120.036
Worm
negative regulation of cell deathGO:0060548810.036
pigment metabolic processGO:0042440840.036
regulation of protein metabolic processGO:00512462560.036
post embryonic appendage morphogenesisGO:00351203850.035
cell projection assemblyGO:0030031940.035
regulation of hemocyte proliferationGO:0035206370.035
spermatid differentiationGO:00485151140.035
dendrite regenerationGO:003110420.034
appendage developmentGO:00487364010.034
Mouse
epithelial cell fate determination open tracheal systemGO:000742520.034
intracellular signal transductionGO:00355563000.033
negative regulation of gtp catabolic processGO:003312510.032
telencephalon developmentGO:002153720.031
response to red or far red lightGO:000963920.031
negative regulation of notch signaling pathwayGO:0045746410.031
germ cell migrationGO:0008354430.030
epithelial tube morphogenesisGO:0060562880.030
Mouse
positive regulation of multicellular organism growthGO:0040018210.028
negative regulation of purine nucleotide catabolic processGO:003312210.028
oocyte fate commitmentGO:004860020.027
cellular protein modification processGO:00064644380.027
negative regulation of cellular component organizationGO:00511291080.026
posttranscriptional regulation of gene expressionGO:00106081450.026
cellular macromolecule catabolic processGO:00442651360.026
developmental programmed cell deathGO:00106231380.026
regulation of cell proliferation involved in compound eye morphogenesisGO:200049520.026
negative regulation of mitotic cell cycleGO:00459301090.025
regulation of hydrolase activityGO:0051336970.025
reproductive behaviorGO:00190981220.025
Worm
chromatin modificationGO:00165681470.024
meiotic spindle checkpointGO:004477910.024
detection of virusGO:000959710.024
rna splicingGO:0008380830.024
positive regulation of synaptic transmission cholinergicGO:003222420.024
camera type eye developmentGO:004301040.023
Zebrafish
regulation of epithelial cell proliferationGO:005067840.023
negative regulation of terminal cell fate specification open tracheal systemGO:003515520.023
muscle cell fate commitmentGO:0042693140.022
regulation of planar cell polarity pathway involved in axis elongationGO:200004020.022
forebrain developmentGO:003090020.022
purine ribonucleoside monophosphate catabolic processGO:0009169380.022
specification of segmental identity antennal segmentGO:000738320.022
vesicle mediated transportGO:00161923810.021
Worm
peripheral nervous system neuron differentiationGO:004893480.020
anterior posterior pattern specificationGO:00099521360.020
Mouse
meiotic dna repair synthesisGO:000071130.020
cellular catabolic processGO:00442483720.020
camera type eye morphogenesisGO:004859320.020
Zebrafish
skin developmentGO:0043588650.020
negative regulation of response to stimulusGO:00485852580.020
cellular amide metabolic processGO:0043603800.020
regulation of cell cycle phase transitionGO:19019871300.020
Mouse
protein transportGO:00150311550.019
morphogenesis of a branching structureGO:0001763450.019
Mouse
dna conformation changeGO:00711031050.019
rna processingGO:00063961470.019
cellular component assembly involved in morphogenesisGO:00109271510.019
nitric oxide metabolic processGO:004620910.019
maintenance of blood brain barrierGO:003563310.019
regulation of apoptotic processGO:00429811300.019
determination of adult lifespanGO:00083401370.018
meiotic nuclear envelope disassemblyGO:005107820.018
maintenance of neuroblast polarityGO:004520130.018
negative regulation of cell communicationGO:00106482230.018
response to etherGO:004547210.018
protein modification processGO:00362114380.018
microtubule slidingGO:005101230.018
regulation of centriole replicationGO:004659920.017
covalent chromatin modificationGO:00165691060.017
response to organic cyclic compoundGO:0014070890.017
positive regulation of neuron projection regenerationGO:007057230.017
protein localization to nuclear envelopeGO:009043520.017
positive regulation of cell migrationGO:003033520.017
regulation of response to stressGO:00801342000.017
g1 s transition of mitotic cell cycleGO:0000082310.017
mushroom body developmentGO:0016319700.017
organic substance transportGO:00717022570.016
phosphorylationGO:00163102940.016
establishment or maintenance of polarity of larval imaginal disc epitheliumGO:001633630.016
cytoplasmic transportGO:00164821300.016
photoreceptor cell differentiationGO:00465301700.016
nephron epithelium morphogenesisGO:007208830.016
Mouse
regionalizationGO:00030024160.015
Mouse
ectodermal placode formationGO:006078840.015
regulation of syncytial blastoderm mitotic cell cycleGO:000734840.015
gene loopingGO:009020220.015
posttranscriptional gene silencingGO:0016441460.015
dna integrationGO:001507410.015
regulation of intracellular signal transductionGO:19025312360.015
dendrite morphogenesisGO:00488131990.015
smoothened signaling pathway involved in ventral spinal cord patterningGO:002191000.015
negative regulation of dna templated transcription initiationGO:200014310.015
response to bacteriumGO:00096171980.015
negative regulation of cell developmentGO:0010721620.015
Mouse
blastoderm segmentationGO:00073501590.015
regulation of cell cycle g1 s phase transitionGO:1902806230.015
asymmetric neuroblast division resulting in ganglion mother cell formationGO:005506020.014
ganglion mother cell fate determinationGO:000740220.014
hematopoietic or lymphoid organ developmentGO:0048534570.014
Mouse
eye photoreceptor cell differentiationGO:00017541450.014
positive regulation of transcription involved in g2 m transition of mitotic cell cycleGO:009028210.014
reactive oxygen species biosynthetic processGO:190340900.014
eye antennal disc morphogenesisGO:0007455340.014
imaginal disc derived wing vein morphogenesisGO:0008586440.014
negative regulation of signalingGO:00230572190.014
p granule organizationGO:003071940.014
regulation of phosphorylationGO:00423251470.014
trichome morphogenesisGO:001009030.014
regulation of ran gtpase activityGO:003231610.014
regulation of phosphatase activityGO:001092130.014
negative regulation of activin receptor signaling pathwayGO:003292610.013
retina development in camera type eyeGO:006004140.013
Zebrafish
posttranscriptional gene silencing by rnaGO:0035194450.013
positive regulation of store operated calcium channel activityGO:190134110.013
response to uv bGO:001022410.013
regulation of protein stabilityGO:0031647430.013
positive regulation of multicellular organismal processGO:00512401430.013
positive regulation of protein modification processGO:0031401580.013
anterior posterior axis specification follicular epitheliumGO:003071420.013
negative regulation of nucleotide metabolic processGO:004598040.013
histone h3 k36 methylationGO:001045210.013
deathGO:00162652840.013
apoptotic processGO:00069151590.013
leg disc developmentGO:0035218920.013
trichome differentiationGO:001002630.013
response to red lightGO:001011420.013
peptidyl serine modificationGO:001820970.013
embryonic morphogenesisGO:00485982060.013
Zebrafish Mouse Worm
positive regulation of protein localization to nucleusGO:1900182210.013
cellular response to nutrientGO:003167010.013
establishment of protein localizationGO:00451841630.012
response to external biotic stimulusGO:00432072930.012
positive regulation of response to stimulusGO:00485843230.012
cellular response to chemical stimulusGO:00708871990.012
heart developmentGO:0007507820.012
Zebrafish
positive regulation of phosphorylationGO:0042327870.012
positive regulation of signal transductionGO:00099672230.012
positive regulation of posttranscriptional gene silencingGO:006014850.012
intermediate filament cytoskeleton organizationGO:004510410.012
reactive nitrogen species metabolic processGO:200105700.012
cell migrationGO:00164772380.012
Zebrafish Worm
dna templated transcriptional start site selectionGO:000117310.012
regulation of reactive oxygen species biosynthetic processGO:190342600.011
anterior posterior axis specificationGO:00099481090.011
gonad developmentGO:0008406500.011
developmental growth involved in morphogenesisGO:0060560650.011
response to organic substanceGO:00100332840.011
positive regulation of intracellular signal transductionGO:19025331160.011
oxoacid metabolic processGO:00434361030.011
carboxylic acid metabolic processGO:0019752920.011
lipid localizationGO:0010876540.011
Worm
negative regulation of cellular response to hypoxiaGO:190003810.011
regulation of striated muscle contractionGO:000694220.011
negative regulation of cellular protein metabolic processGO:0032269850.011
oxidation reduction processGO:00551141230.010
negative regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:001705510.010
synaptic vesicle budding from presynaptic membraneGO:001618510.010
neuroblast proliferationGO:0007405740.010
regulation of chromosome condensationGO:006062310.010
regulation of i kappab kinase nf kappab signalingGO:004312220.010
regulation of preblastoderm mitotic cell cycleGO:000734710.010
meiotic sister chromatid cohesion centromericGO:005175420.010
tube developmentGO:00352952440.010
Mouse Worm

exd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
neurodegenerative diseaseDOID:128900.013
central nervous system diseaseDOID:33100.013
spinocerebellar degenerationDOID:247800.013
spinocerebellar ataxiaDOID:144100.013
disease of anatomical entityDOID:700.013
nervous system diseaseDOID:86300.013
cardiovascular system diseaseDOID:128700.013
artery diseaseDOID:005082800.013
vascular diseaseDOID:17800.013
aortic diseaseDOID:52000.013
pilomatrixomaDOID:537400.012
integumentary system benign neoplasmDOID:006012100.012
benign neoplasmDOID:006007200.012
disease of cellular proliferationDOID:1456600.012
skin benign neoplasmDOID:316500.012
organ system benign neoplasmDOID:006008500.012
hair follicle neoplasmDOID:537500.012
hajdu cheney syndromeDOID:273600.012
syndromeDOID:22500.012