Drosophila melanogaster

140 known processes

Stim (Dmel_CG9126)

Stromal interaction molecule

(Aliases: stim1,STIM,D-Stim,Dmel\CG9126,CG9126,dstim,dStim,D-STIM,dSTIM)

Stim biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
eye developmentGO:00016543230.645
regulation of catalytic activityGO:00507901850.624
ion transportGO:00068111450.608
regulation of vesicle mediated transportGO:0060627590.583
Worm
phosphorylationGO:00163102940.573
endocytosisGO:00068973100.550
Worm
ion transmembrane transportGO:00342201220.528
lipid metabolic processGO:00066291210.490
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.475
positive regulation of programmed cell deathGO:0043068620.470
regulation of apoptotic processGO:00429811300.407
regulation of phosphate metabolic processGO:00192202100.403
regulation of mitotic cell cycleGO:00073461900.403
regulation of notch signaling pathwayGO:00085931000.372
wing disc morphogenesisGO:00074723440.362
catabolic processGO:00090564090.353
negative regulation of cellular metabolic processGO:00313243820.340
appendage morphogenesisGO:00351073970.335
imaginal disc derived appendage morphogenesisGO:00351143950.318
biological adhesionGO:00226101380.305
interspecies interaction between organismsGO:0044419160.290
extracellular structure organizationGO:0043062460.275
intracellular signal transductionGO:00355563000.272
protein phosphorylationGO:00064681690.272
protein complex biogenesisGO:00702712010.266
negative regulation of catalytic activityGO:0043086420.265
cell junction organizationGO:0034330570.250
morphogenesis of embryonic epitheliumGO:0016331940.244
imaginal disc derived appendage developmentGO:00487373990.241
morphogenesis of an epitheliumGO:00020092760.240
small molecule metabolic processGO:00442813050.234
actin filament based processGO:00300292200.233
vesicle mediated transportGO:00161923810.228
Worm
regulation of molecular functionGO:00650092170.223
cation transportGO:00068121100.219
cell cell junction organizationGO:0045216550.216
cell adhesionGO:00071551360.209
mitotic dna damage checkpointGO:0044773740.206
regulation of transmembrane transportGO:0034762270.204
positive regulation of macromolecule metabolic processGO:00106044050.200
cell cycle checkpointGO:0000075950.198
enzyme linked receptor protein signaling pathwayGO:00071671790.197
regulation of protein modification processGO:00313991120.196
regulation of cell deathGO:00109411730.193
positive regulation of response to stimulusGO:00485843230.193
cell proliferationGO:00082832990.191
protein modification processGO:00362114380.189
cellular protein localizationGO:00346131600.189
compound eye developmentGO:00487493070.186
actin filament organizationGO:00070151260.181
cation transmembrane transportGO:0098655880.180
post embryonic appendage morphogenesisGO:00351203850.177
actin cytoskeleton organizationGO:00300362060.176
camera type eye developmentGO:004301040.176
organic substance transportGO:00717022570.176
neuron projection guidanceGO:00974852410.175
regulation of cell cycle processGO:00105641810.173
proteasomal protein catabolic processGO:0010498590.169
apoptotic processGO:00069151590.166
synaptic growth at neuromuscular junctionGO:00511241190.162
protein complex assemblyGO:00064612000.162
regulation of programmed cell deathGO:00430671520.161
regulation of cellular protein metabolic processGO:00322682430.156
regulation of cellular response to stressGO:0080135890.152
negative regulation of molecular functionGO:0044092510.148
negative regulation of phosphorylationGO:0042326350.148
embryonic morphogenesisGO:00485982060.146
negative regulation of phosphate metabolic processGO:0045936450.145
appendage developmentGO:00487364010.139
proteolysisGO:00065081920.139
signal transduction by phosphorylationGO:00230141070.136
compound eye morphogenesisGO:00017452490.136
g2 dna damage checkpointGO:0031572690.136
synaptic transmissionGO:00072682880.135
notch signaling pathwayGO:00072191200.135
response to extracellular stimulusGO:00099911160.135
cell cell signaling involved in cell fate commitmentGO:00451682100.132
metal ion homeostasisGO:0055065440.131
stress activated mapk cascadeGO:0051403520.131
carbohydrate metabolic processGO:0005975820.130
imaginal disc derived wing morphogenesisGO:00074763370.128
ribose phosphate metabolic processGO:00196931450.127
regulation of phosphorus metabolic processGO:00511742100.125
cellular protein modification processGO:00064644380.125
negative regulation of protein metabolic processGO:0051248850.125
cellular lipid metabolic processGO:0044255830.124
mitotic cell cycle checkpointGO:0007093880.122
maintenance of protein locationGO:0045185280.121
regulation of protein kinase activityGO:0045859510.119
deathGO:00162652840.119
positive regulation of cellular component biogenesisGO:0044089800.118
cell cycle phase transitionGO:00447701400.114
mitotic g2 m transition checkpointGO:0044818700.113
cellular catabolic processGO:00442483720.113
single organism catabolic processGO:00447122280.113
negative regulation of signalingGO:00230572190.112
single organism behaviorGO:00447083910.111
embryonic development via the syncytial blastodermGO:00017001480.109
regulation of cell cycleGO:00517262910.109
regulation of response to stressGO:00801342000.109
regulation of multicellular organismal developmentGO:20000264140.108
regulation of cell cycle phase transitionGO:19019871300.104
synapse organizationGO:00508081960.102
organonitrogen compound metabolic processGO:19015643180.101
chemical homeostasisGO:0048878920.098
jnk cascadeGO:0007254500.098
regulation of cytoskeleton organizationGO:0051493890.098
single organism biosynthetic processGO:00447112060.097
pigmentationGO:0043473750.097
cellular response to chemical stimulusGO:00708871990.094
macromolecular complex assemblyGO:00650032560.094
negative regulation of cell differentiationGO:00455961430.093
regulation of stress activated mapk cascadeGO:0032872410.093
epidermal growth factor receptor signaling pathwayGO:0007173580.093
dna integrity checkpointGO:0031570810.093
metal ion transportGO:0030001740.093
response to endogenous stimulusGO:00097191190.091
axon guidanceGO:00074112330.091
positive regulation of apoptotic processGO:0043065470.091
negative regulation of cell communicationGO:00106482230.090
regulation of localizationGO:00328792750.090
cellular response to dna damage stimulusGO:00069742230.090
cellular macromolecule localizationGO:00707272200.088
carbohydrate derivative metabolic processGO:19011352170.088
organophosphate metabolic processGO:00196371950.087
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.086
regulation of mitotic cell cycle phase transitionGO:19019901300.086
regulation of organelle organizationGO:00330431960.084
eye morphogenesisGO:00485922600.084
ribonucleotide metabolic processGO:00092591450.084
secretionGO:00469031090.084
larval developmentGO:00021641040.082
ion homeostasisGO:0050801550.082
cellular response to endogenous stimulusGO:0071495800.081
negative regulation of cellular protein metabolic processGO:0032269850.081
actin filament bundle organizationGO:0061572280.081
programmed cell deathGO:00125012570.080
regulation of transportGO:00510491810.080
axonogenesisGO:00074092900.080
phagocytosisGO:00069092150.079
Worm
chaeta developmentGO:0022416970.079
positive regulation of developmental processGO:00510941430.079
purine containing compound catabolic processGO:00725231120.079
ubiquitin dependent protein catabolic processGO:0006511780.079
skin developmentGO:0043588650.079
regionalizationGO:00030024160.078
neuromuscular junction developmentGO:00075281490.078
regulation of synapse structure and activityGO:00508031280.075
regulation of endopeptidase activityGO:0052548360.074
cell cell junction assemblyGO:0007043380.073
tissue morphogenesisGO:00487292970.071
positive regulation of multicellular organism growthGO:0040018210.070
negative regulation of phosphorus metabolic processGO:0010563450.070
positive regulation of multicellular organismal processGO:00512401430.070
Worm
mitotic cell cycle phase transitionGO:00447721380.069
positive regulation of phosphate metabolic processGO:00459371390.068
negative regulation of response to stimulusGO:00485852580.067
nucleocytoplasmic transportGO:0006913720.066
response to nutrient levelsGO:00316671140.066
epithelial cell developmentGO:00020642740.065
peptidyl amino acid modificationGO:00181931050.063
protein catabolic processGO:00301631010.061
positive regulation of signal transductionGO:00099672230.060
response to organic substanceGO:00100332840.060
regulation of phosphorylationGO:00423251470.060
regulation of cell developmentGO:00602842150.060
establishment of localization in cellGO:00516494020.059
defense responseGO:00069523000.059
positive regulation of nitrogen compound metabolic processGO:00511733540.058
regulation of map kinase activityGO:0043405170.058
epidermis developmentGO:0008544650.058
dna damage checkpointGO:0000077780.058
central nervous system developmentGO:00074172010.058
negative regulation of cell developmentGO:0010721620.057
negative regulation of cell cycle phase transitionGO:19019881030.056
adherens junction organizationGO:0034332270.056
regulation of protein serine threonine kinase activityGO:0071900250.055
cellular nitrogen compound catabolic processGO:00442701650.054
gland developmentGO:00487321910.054
carbohydrate derivative biosynthetic processGO:1901137850.054
gliogenesisGO:0042063800.054
head developmentGO:00603221350.053
positive regulation of molecular functionGO:00440931360.053
mapk cascadeGO:00001651070.052
regulation of multi organism processGO:00439001310.052
proteolysis involved in cellular protein catabolic processGO:0051603830.051
nucleoside catabolic processGO:00091641120.051
erbb signaling pathwayGO:0038127580.051
protein localizationGO:00081042840.051
nucleoside metabolic processGO:00091161270.050
regulation of response to external stimulusGO:00321011150.050
regulation of cell differentiationGO:00455953020.049
cell deathGO:00082192790.049
inorganic cation transmembrane transportGO:0098662610.049
stress activated protein kinase signaling cascadeGO:0031098550.048
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.048
positive regulation of multi organism processGO:0043902400.048
organic substance catabolic processGO:19015753080.047
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.047
epithelial cell differentiationGO:00308553220.047
purine ribonucleotide metabolic processGO:00091501450.046
organic acid metabolic processGO:00060821030.046
regulation of stress activated protein kinase signaling cascadeGO:0070302420.045
positive regulation of phagocytosis engulfmentGO:006010010.045
Worm
lateral inhibitionGO:00463312060.045
regulation of transferase activityGO:0051338580.045
negative regulation of cell cycle g2 m phase transitionGO:190275080.044
negative regulation of fibroblast growth factor receptor signaling pathwayGO:004003720.044
hair cell differentiationGO:0035315470.043
fatty acid metabolic processGO:0006631200.041
positive regulation of developmental growthGO:0048639620.041
peptidyl threonine phosphorylationGO:001810720.041
regulation of developmental growthGO:00486381740.041
negative regulation of signal transductionGO:00099682060.040
negative regulation of mitotic cell cycle phase transitionGO:19019911030.039
negative regulation of kinase activityGO:0033673160.039
response to starvationGO:0042594970.039
cell divisionGO:00513012480.038
regulation of hydrolase activityGO:0051336970.037
purine nucleotide metabolic processGO:00061631460.037
negative regulation of cell cycleGO:00457861160.037
nucleotide metabolic processGO:00091171610.037
lamellipodium organizationGO:0097581210.036
regulation of cellular component biogenesisGO:00440872010.036
protein localization to nucleusGO:0034504550.036
developmental growthGO:00485892800.036
male meiosis cytokinesisGO:0007112260.035
positive regulation of nucleotide metabolic processGO:0045981550.035
centrosome organizationGO:00512971630.035
negative regulation of cell deathGO:0060548810.035
aromatic compound catabolic processGO:00194391660.035
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.035
positive regulation of signalingGO:00230562430.035
regulation of ion transportGO:0043269390.034
maintenance of location in cellGO:0051651280.034
response to osmotic stressGO:0006970140.034
multi multicellular organism processGO:00447061230.034
positive regulation of nucleobase containing compound metabolic processGO:00459353320.034
cellular metal ion homeostasisGO:0006875310.033
positive regulation of cellular component organizationGO:00511301560.033
Worm
maintenance of protein location in cellGO:0032507260.032
modification dependent macromolecule catabolic processGO:0043632790.032
cell junction assemblyGO:0034329420.032
forebrain developmentGO:003090020.032
immune responseGO:00069552460.032
oxoacid metabolic processGO:00434361030.032
homeostatic processGO:00425921990.031
response to nitrogen compoundGO:1901698900.031
memoryGO:0007613940.031
phagocytosis engulfmentGO:0006911110.031
Worm
posttranscriptional regulation of gene expressionGO:00106081450.031
transforming growth factor beta receptor signaling pathwayGO:0007179160.031
chemotaxisGO:00069352490.030
positive regulation of cell communicationGO:00106472500.030
cytokinesisGO:0000910900.030
regulation of pathway restricted smad protein phosphorylationGO:006039310.030
cell growthGO:00160491080.030
embryo development ending in birth or egg hatchingGO:00097921520.030
negative regulation of cell cycle processGO:00109481090.030
cytoplasmic transportGO:00164821300.029
respiratory system developmentGO:00605412130.029
positive regulation of growthGO:0045927750.029
regulation of jnk cascadeGO:0046328400.029
regulation of anatomical structure morphogenesisGO:00226032420.029
organophosphate catabolic processGO:00464341120.028
negative regulation of protein phosphorylationGO:0001933170.028
regulation of growthGO:00400082330.028
regulation of multicellular organism growthGO:0040014400.028
regulation of protein localizationGO:0032880760.028
exocrine system developmentGO:00352721620.028
negative regulation of transferase activityGO:0051348180.028
single organism carbohydrate metabolic processGO:0044723720.027
immune system processGO:00023763470.027
mitotic dna integrity checkpointGO:0044774750.027
epithelial cell morphogenesis involved in gastrulationGO:000338170.027
apoptotic cell clearanceGO:0043277140.026
Worm
regulation of mitosisGO:0007088560.026
imaginal disc derived wing vein specificationGO:0007474480.026
regulation of defense response to virus by hostGO:0050691100.026
cellular macromolecule catabolic processGO:00442651360.026
localization of cellGO:00516742570.025
regulation of hemocyte proliferationGO:0035206370.025
regulation of erbb signaling pathwayGO:1901184420.025
negative regulation of actin filament depolymerizationGO:003083520.025
positive regulation of protein transportGO:0051222370.025
endosomal transportGO:0016197440.025
establishment of protein localizationGO:00451841630.025
positive regulation of catalytic activityGO:00430851180.024
negative regulation of protein modification processGO:0031400290.024
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.024
apical constriction involved in gastrulationGO:000338470.024
carboxylic acid metabolic processGO:0019752920.024
regulation of nucleocytoplasmic transportGO:0046822350.024
cellular response to organic substanceGO:00713101320.024
regulation of secretionGO:0051046440.023
regulation of cytoplasmic transportGO:1903649470.023
regulation of synapse organizationGO:00508071100.023
symbiosis encompassing mutualism through parasitismGO:0044403160.023
cellular response to nutrient levelsGO:0031669620.023
glycosyl compound catabolic processGO:19016581120.022
negative regulation of erbb signaling pathwayGO:1901185290.022
positive regulation of protein kinase activityGO:0045860250.022
detection of abiotic stimulusGO:0009582660.022
regulation of metal ion transportGO:0010959150.022
positive regulation of cellular protein metabolic processGO:00322701180.021
negative regulation of notch signaling pathwayGO:0045746410.021
positive regulation of cell deathGO:0010942690.021
sensory organ precursor cell divisionGO:0045035100.021
heterocycle catabolic processGO:00467001660.021
regulation of mapk cascadeGO:0043408920.021
intracellular transportGO:00469072280.021
axon developmentGO:00615642970.021
spermatid differentiationGO:00485151140.021
cellular response to growth factor stimulusGO:0071363300.020
open tracheal system developmentGO:00074242040.020
transcription from rna polymerase ii promoterGO:00063663680.020
positive regulation of protein metabolic processGO:00512471280.020
dendrite developmentGO:00163582040.020
regulation of immune system processGO:00026821760.020
sensory organ morphogenesisGO:00905962600.020
regulation of protein phosphorylationGO:0001932640.020
regulation of protein metabolic processGO:00512462560.020
response to abiotic stimulusGO:00096283410.020
purine ribonucleoside metabolic processGO:00461281270.020
calcium ion homeostasisGO:0055074230.020
response to lipopolysaccharideGO:003249640.019
positive regulation of ion transmembrane transporter activityGO:003241440.019
positive regulation of defense response to virus by hostGO:0002230100.019
purine nucleoside metabolic processGO:00422781270.019
cellular response to nitrogen compoundGO:1901699510.019
regulation of nervous system developmentGO:00519602480.019
negative regulation of multicellular organismal processGO:00512411420.019
carbohydrate derivative catabolic processGO:19011361180.019
positive regulation of macromolecule biosynthetic processGO:00105572830.019
spinal cord patterningGO:002151110.019
actin filament based movementGO:0030048260.019
regulation of nuclear divisionGO:0051783580.019
dna replicationGO:0006260480.019
cellular cation homeostasisGO:0030003380.018
eye photoreceptor cell differentiationGO:00017541450.018
chaeta morphogenesisGO:0008407420.018
kidney epithelium developmentGO:007207330.018
neurological system processGO:00508773580.018
actin filament polymerizationGO:0030041270.018
mitotic g2 dna damage checkpointGO:0007095690.018
larval feeding behaviorGO:0030536150.018
cellular response to starvationGO:0009267610.018
regulation of cell shapeGO:00083601130.018
purine nucleotide catabolic processGO:00061951090.018
mitochondrial membrane organizationGO:000700630.017
divalent inorganic cation homeostasisGO:0072507290.017
ribonucleoside triphosphate catabolic processGO:00092031080.017
endothelium developmentGO:000315860.017
protein autophosphorylationGO:0046777150.017
single organism cellular localizationGO:19025801800.017
response to biotic stimulusGO:00096072940.017
connective tissue developmentGO:006144830.016
imaginal disc derived wing hair organizationGO:0035317450.016
notch receptor processingGO:0007220130.016
positive regulation of cell developmentGO:0010720610.016
response to oxygen containing compoundGO:19017002000.016
protein localization to organelleGO:0033365820.016
regulation of kinase activityGO:0043549530.016
dorsal closureGO:0007391790.016
vesicle targetingGO:000690310.016
nucleoside phosphate catabolic processGO:19012921100.016
regulation of phosphatidylinositol 3 kinase signalingGO:001406640.016
positive regulation of jnk cascadeGO:0046330160.016
positive regulation of transportGO:0051050920.016
histone h2a ubiquitinationGO:003352220.016
regulation of peptidase activityGO:0052547390.016
organ or tissue specific immune responseGO:0002251100.016
negative regulation of cellular component organizationGO:00511291080.015
secretion by cellGO:00329401010.015
body morphogenesisGO:001017120.015
developmental pigmentationGO:0048066680.015
positive regulation of apoptotic signaling pathwayGO:200123540.015
purine nucleoside triphosphate metabolic processGO:00091441190.015
positive regulation of cell differentiationGO:0045597640.015
regulation of endocytosisGO:0030100370.015
Worm
single organism membrane fusionGO:0044801420.015
spermatid developmentGO:0007286980.015
nucleoside triphosphate metabolic processGO:00091411200.014
regulation of tube architecture open tracheal systemGO:0035152680.014
unidimensional cell growthGO:0009826150.014
tube developmentGO:00352952440.014
cellular ketone metabolic processGO:0042180240.014
epidermal cell differentiationGO:0009913510.014
negative regulation of multi organism processGO:0043901290.014
negative regulation of programmed cell deathGO:0043069720.014
regulation of catabolic processGO:00098941700.014
cardiovascular system developmentGO:0072358820.014
salivary gland developmentGO:00074311620.014
cellular amino acid metabolic processGO:0006520610.014
actin filament bundle assemblyGO:0051017260.014
ameboidal type cell migrationGO:00016671510.014
negative regulation of rna biosynthetic processGO:19026792400.013
regulation of i kappab kinase nf kappab signalingGO:004312220.013
centrosome cycleGO:00070981370.013
modification dependent protein catabolic processGO:0019941780.013
ribonucleoside triphosphate metabolic processGO:00091991190.013
spindle organizationGO:00070512530.013
response to organonitrogen compoundGO:0010243750.013
heparin metabolic processGO:003020240.013
salivary gland morphogenesisGO:00074351450.013
negative regulation of apoptotic processGO:0043066630.013
nucleobase containing small molecule metabolic processGO:00550861740.013
macromolecule catabolic processGO:00090571610.013
response to light stimulusGO:00094161240.013
positive regulation of notch signaling pathwayGO:0045747340.013
positive regulation of phosphorylationGO:0042327870.013
notum morphogenesisGO:004880240.013
taxisGO:00423303040.013
circulatory system processGO:0003013370.013
cellular amine metabolic processGO:0044106120.013
hematopoietic or lymphoid organ developmentGO:0048534570.013
calcium ion transportGO:0006816240.013
limb developmentGO:006017310.013
alcohol metabolic processGO:0006066250.013
single organismal cell cell adhesionGO:0016337450.013
signal transduction in response to dna damageGO:004277030.013
heparan sulfate proteoglycan metabolic processGO:0030201100.012
scf dependent proteasomal ubiquitin dependent protein catabolic processGO:003114610.012
growthGO:00400073590.012
cellular response to hormone stimulusGO:0032870440.012
positive regulation of hydrolase activityGO:0051345780.012
regulation of protein stabilityGO:0031647430.012
membrane organizationGO:00610241120.012
Worm
locomotory behaviorGO:00076261760.012
meiotic cell cycleGO:00513211710.012
negative regulation of neuron apoptotic processGO:0043524140.012
cellular protein catabolic processGO:0044257830.012
cognitionGO:00508901410.012
limb morphogenesisGO:003510810.012
nucleobase containing compound catabolic processGO:00346551650.012
peripheral nervous system developmentGO:0007422520.012
dephosphorylationGO:0016311510.012
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.012
nephron epithelium morphogenesisGO:007208830.012
regulation of cell divisionGO:0051302720.012
detection of external stimulusGO:0009581660.012
regulation of phosphatase activityGO:001092130.012
inositol lipid mediated signalingGO:004801740.011
larval behaviorGO:0030537420.011
mesenchymal cell differentiationGO:004876210.011
cellular chemical homeostasisGO:0055082400.011
ribonucleotide catabolic processGO:00092611090.011
eggshell chorion gene amplificationGO:000730790.011
response to bacteriumGO:00096171980.011
regulation of protein localization to plasma membraneGO:190307670.011
ribonucleoside metabolic processGO:00091191270.011
neuromuscular synaptic transmissionGO:0007274670.011
positive regulation of gene expressionGO:00106282900.011
positive regulation of cellular biosynthetic processGO:00313283160.011
negative regulation of nitrogen compound metabolic processGO:00511722650.011
macroautophagyGO:0016236420.011
cell fate determinationGO:0001709910.011
meiotic cytokinesisGO:0033206330.011
regulation of symbiosis encompassing mutualism through parasitismGO:0043903150.010
response to peptide hormoneGO:0043434290.010
regulation of actin polymerization or depolymerizationGO:0008064270.010
positive regulation of cellular catabolic processGO:0031331950.010
glycosyl compound metabolic processGO:19016571270.010
regulation of protein catabolic processGO:0042176550.010
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.010
positive regulation of protein localization to nucleusGO:1900182210.010
cellular response to oxygen containing compoundGO:1901701790.010
cortical actin cytoskeleton organizationGO:0030866240.010
regulation of lipid storageGO:0010883220.010

Stim disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.070
nervous system diseaseDOID:86300.023
connective tissue diseaseDOID:6500.018
musculoskeletal system diseaseDOID:1700.018