Drosophila melanogaster

77 known processes

Scm (Dmel_CG9495)

Sex comb on midleg

(Aliases: SCM,scm,Dmel\CG9495,CG9495,Su(z)302,l(3)85Ef)

Scm biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of rna metabolic processGO:00512532510.998
chromosome organizationGO:00512763600.994
Mouse
chromatin silencingGO:0006342760.986
negative regulation of nucleobase containing compound metabolic processGO:00459342610.977
chromatin organizationGO:00063252070.976
Mouse
negative regulation of biosynthetic processGO:00098902770.976
negative regulation of nitrogen compound metabolic processGO:00511722650.968
negative regulation of macromolecule biosynthetic processGO:00105582700.962
negative regulation of cellular biosynthetic processGO:00313272770.962
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.961
negative regulation of gene expression epigeneticGO:0045814770.961
negative regulation of transcription dna templatedGO:00458922370.957
negative regulation of nucleic acid templated transcriptionGO:19035072400.945
regulation of gene expression epigeneticGO:00400291280.938
negative regulation of rna biosynthetic processGO:19026792400.915
negative regulation of cellular metabolic processGO:00313243820.799
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.795
positive regulation of biosynthetic processGO:00098913160.794
covalent chromatin modificationGO:00165691060.790
chromatin modificationGO:00165681470.732
Mouse
gene silencingGO:00164581380.705
histone modificationGO:00165701060.704
dna metabolic processGO:00062592270.684
chemotaxisGO:00069352490.663
imaginal disc derived wing morphogenesisGO:00074763370.655
positive regulation of rna metabolic processGO:00512542710.648
negative regulation of gene expressionGO:00106293870.617
regulation of cell differentiationGO:00455953020.582
positive regulation of macromolecule biosynthetic processGO:00105572830.578
taxisGO:00423303040.577
deathGO:00162652840.545
imaginal disc derived appendage developmentGO:00487373990.479
neurological system processGO:00508773580.479
neuron projection guidanceGO:00974852410.477
transcription from rna polymerase ii promoterGO:00063663680.457
ovarian follicle cell developmentGO:00307072480.382
germ line cyst encapsulationGO:004813880.367
ovarian follicle cell stalk formationGO:0030713170.351
regulation of cell deathGO:00109411730.347
mitotic cell cycle embryonicGO:0045448380.320
imaginal disc derived appendage morphogenesisGO:00351143950.313
peptidyl lysine modificationGO:0018205570.310
regulation of transcription from rna polymerase ii promoterGO:00063573780.306
internal peptidyl lysine acetylationGO:0018393380.304
protein modification by small protein conjugation or removalGO:00706471060.303
internal protein amino acid acetylationGO:0006475380.300
protein modification processGO:00362114380.279
wing disc morphogenesisGO:00074723440.279
positive regulation of cellular biosynthetic processGO:00313283160.268
negative regulation of response to stimulusGO:00485852580.257
regulation of response to gamma radiationGO:200122840.253
blastoderm segmentationGO:00073501590.252
histone h3 k27 methylationGO:007073460.242
positive regulation of transcription dna templatedGO:00458932660.235
anterior posterior pattern specificationGO:00099521360.226
Mouse
positive regulation of gene expressionGO:00106282900.225
sensory organ morphogenesisGO:00905962600.225
programmed cell deathGO:00125012570.223
histone acetylationGO:0016573380.222
protein acetylationGO:0006473390.203
dendrite developmentGO:00163582040.197
axon guidanceGO:00074112330.197
axonogenesisGO:00074092900.194
chromatin mediated maintenance of transcriptionGO:004809670.193
negative regulation of response to gamma radiationGO:200122940.192
positive regulation of nucleobase containing compound metabolic processGO:00459353320.190
appendage developmentGO:00487364010.189
regulation of cell morphogenesisGO:00226041630.186
segmentationGO:00352822070.184
stem cell differentiationGO:00488631170.177
positive regulation of cellular component organizationGO:00511301560.173
dendrite morphogenesisGO:00488131990.167
positive regulation of macromolecule metabolic processGO:00106044050.166
eggshell chorion assemblyGO:0007306660.163
response to abiotic stimulusGO:00096283410.163
positive regulation of nitrogen compound metabolic processGO:00511733540.152
chromatin remodelingGO:0006338720.151
Mouse
tripartite regional subdivisionGO:00073511030.151
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.143
negative regulation of cell differentiationGO:00455961430.139
appendage morphogenesisGO:00351073970.133
apoptotic processGO:00069151590.133
male gamete generationGO:00482322010.130
Mouse
meiotic nuclear divisionGO:00071261510.129
positive regulation of rna biosynthetic processGO:19026802660.124
positive regulation of cell morphogenesis involved in differentiationGO:0010770120.123
negative regulation of developmental processGO:00510932010.122
regulation of response to biotic stimulusGO:0002831630.121
regulation of nervous system developmentGO:00519602480.108
peptidyl lysine acetylationGO:0018394390.107
response to oxygen containing compoundGO:19017002000.107
post embryonic appendage morphogenesisGO:00351203850.105
trunk segmentationGO:003529080.102
regulation of neurogenesisGO:00507671580.102
histone ubiquitinationGO:001657440.097
germarium derived female germ line cyst encapsulationGO:003070880.097
cell motilityGO:00488702510.096
regulation of protein metabolic processGO:00512462560.091
peptidyl amino acid modificationGO:00181931050.088
regulation of cell developmentGO:00602842150.088
regulation of anatomical structure morphogenesisGO:00226032420.086
specification of segmental identity trunkGO:003529270.085
regulation of chromatin silencingGO:0031935360.084
periodic partitioningGO:0007365290.084
germ line stem cell divisionGO:0042078250.082
immune system processGO:00023763470.082
dendrite guidanceGO:0070983210.080
regulation of response to external stimulusGO:00321011150.078
embryonic pattern specificationGO:00098801740.078
renal tubule developmentGO:0061326640.078
leg disc morphogenesisGO:0007478800.076
cell migrationGO:00164772380.076
negative regulation of chromatin silencingGO:003193690.072
torso signaling pathwayGO:0008293210.070
regulation of apoptotic processGO:00429811300.070
dna methylationGO:000630640.069
embryonic hemopoiesisGO:0035162260.068
regulation of tube diameterGO:0035296140.067
regulation of multicellular organismal developmentGO:20000264140.067
cuticle developmentGO:0042335860.066
regulation of developmental growthGO:00486381740.066
muscle organ developmentGO:00075171270.065
single organism biosynthetic processGO:00447112060.065
courtship behaviorGO:0007619680.064
chitin based cuticle developmentGO:0040003490.064
protein acylationGO:0043543420.064
regulation of cuticle pigmentationGO:0048079160.063
localization of cellGO:00516742570.062
eggshell formationGO:00307031050.062
chromatin assemblyGO:0031497480.061
eye developmentGO:00016543230.061
response to lipidGO:0033993380.060
regulation of cell morphogenesis involved in differentiationGO:0010769610.059
establishment of localization in cellGO:00516494020.059
positive regulation of cellular protein metabolic processGO:00322701180.058
cell maturationGO:00484691440.057
negative regulation of signal transductionGO:00099682060.057
regulation of dendrite morphogenesisGO:0048814280.056
positive regulation of response to external stimulusGO:0032103440.055
mushroom body developmentGO:0016319700.055
posttranscriptional regulation of gene expressionGO:00106081450.055
small molecule metabolic processGO:00442813050.053
positive regulation of developmental processGO:00510941430.053
regulation of gene silencingGO:0060968630.052
eye photoreceptor cell differentiationGO:00017541450.052
macromolecular complex assemblyGO:00650032560.051
cell deathGO:00082192790.051
protein ubiquitinationGO:0016567700.051
cellular protein modification processGO:00064644380.051
negative regulation of nervous system developmentGO:0051961920.050
organic substance catabolic processGO:19015753080.050
zygotic determination of anterior posterior axis embryoGO:0007354270.050
heart developmentGO:0007507820.050
negative regulation of developmental growthGO:0048640640.049
endocytosisGO:00068973100.048
larval developmentGO:00021641040.047
positive regulation of gene expression epigeneticGO:0045815160.047
regulation of cellular component biogenesisGO:00440872010.047
cellular response to dna damage stimulusGO:00069742230.046
protein modification by small protein conjugationGO:0032446790.046
cellular response to abiotic stimulusGO:0071214580.046
cellular response to oxygen containing compoundGO:1901701790.045
hematopoietic or lymphoid organ developmentGO:0048534570.045
regulation of cellular protein metabolic processGO:00322682430.045
regionalizationGO:00030024160.045
Mouse
tube developmentGO:00352952440.044
histone h4 k16 acetylationGO:004398440.044
negative regulation of neural precursor cell proliferationGO:2000178270.044
digestive tract morphogenesisGO:00485461270.044
epithelial cell developmentGO:00020642740.044
stem cell developmentGO:0048864790.043
protein localizationGO:00081042840.043
axon developmentGO:00615642970.043
negative regulation of growthGO:0045926840.042
multi organism behaviorGO:00517051750.042
dna conformation changeGO:00711031050.041
regulation of cytoskeleton organizationGO:0051493890.040
terminal region determinationGO:0007362250.040
spermatid developmentGO:0007286980.039
response to sterolGO:0036314340.039
methylationGO:0032259470.039
camera type eye morphogenesisGO:004859320.038
digestive tract developmentGO:00485651490.037
immune system developmentGO:0002520570.037
single organism behaviorGO:00447083910.037
response to ecdysoneGO:0035075340.036
embryonic organ developmentGO:0048568500.036
regulation of chromosome organizationGO:0033044640.036
regulation of programmed cell deathGO:00430671520.036
stem cell divisionGO:0017145690.035
limb morphogenesisGO:003510810.035
development of primary sexual characteristicsGO:0045137500.035
positive regulation of nucleic acid templated transcriptionGO:19035082660.035
cellular macromolecular complex assemblyGO:00346221530.035
neuroblast differentiationGO:0014016290.034
regulation of cell cycleGO:00517262910.034
chromatin assembly or disassemblyGO:0006333520.034
negative regulation of multicellular organismal processGO:00512411420.034
segment polarity determinationGO:0007367250.034
posttranscriptional gene silencingGO:0016441460.034
eye antennal disc morphogenesisGO:0007455340.033
regulation of growthGO:00400082330.033
eye morphogenesisGO:00485922600.033
embryonic axis specificationGO:00005781070.032
protein complex biogenesisGO:00702712010.032
locomotory behaviorGO:00076261760.032
posttranscriptional gene silencing by rnaGO:0035194450.032
morphogenesis of an epitheliumGO:00020092760.032
muscle cell differentiationGO:00426921030.031
phosphorylationGO:00163102940.031
intracellular receptor signaling pathwayGO:0030522190.030
epithelial cell migrationGO:00106311480.030
protein transportGO:00150311550.030
compound eye photoreceptor cell differentiationGO:00017511400.030
anterior posterior axis specificationGO:00099481090.029
limb developmentGO:006017310.029
chorion containing eggshell formationGO:00073041050.029
determination of dorsal ventral asymmetryGO:004826230.029
cellular response to extracellular stimulusGO:0031668640.028
compound eye developmentGO:00487493070.028
ribonucleotide metabolic processGO:00092591450.028
cellular macromolecule localizationGO:00707272200.028
regulation of mapk cascadeGO:0043408920.028
negative regulation of organelle organizationGO:0010639560.028
establishment of organelle localizationGO:00516561220.027
germ cell migrationGO:0008354430.027
salivary gland developmentGO:00074311620.027
matingGO:00076181200.026
defense response to other organismGO:00985422250.026
positive regulation of dendrite morphogenesisGO:005077590.026
dna packagingGO:0006323910.026
neuroblast fate commitmentGO:0014017190.026
cell divisionGO:00513012480.025
protein localization to organelleGO:0033365820.025
cellular response to chemical stimulusGO:00708871990.025
body morphogenesisGO:001017120.025
gene silencing by rnaGO:0031047570.025
regulation of response to stressGO:00801342000.025
mapk cascadeGO:00001651070.024
regulation of organelle organizationGO:00330431960.024
glycosyl compound catabolic processGO:19016581120.024
syncytial blastoderm mitotic cell cycleGO:0035186210.024
regulation of synapse assemblyGO:0051963940.024
sterol homeostasisGO:005509240.023
camera type eye developmentGO:004301040.023
regulation of establishment of protein localizationGO:0070201610.023
columnar cuboidal epithelial cell developmentGO:00020662490.023
regulation of cell cycle processGO:00105641810.023
histone h4 acetylationGO:0043967130.023
negative regulation of cell communicationGO:00106482230.023
regulation of histone h3 k27 methylationGO:006108530.023
positive regulation of protein metabolic processGO:00512471280.023
nephron tubule developmentGO:007208030.022
imaginal disc derived female genitalia developmentGO:000748660.022
dna methylation or demethylationGO:004472840.022
positive regulation of response to stimulusGO:00485843230.022
signal transduction by phosphorylationGO:00230141070.022
salivary gland morphogenesisGO:00074351450.022
apposition of dorsal and ventral imaginal disc derived wing surfacesGO:0007475150.021
cellular component assembly involved in morphogenesisGO:00109271510.021
axon midline choice point recognitionGO:0016199260.021
response to other organismGO:00517072930.021
ovarian follicle cell migrationGO:00072971210.021
response to organic substanceGO:00100332840.021
regulation of phosphorylationGO:00423251470.020
molting cycle chitin based cuticleGO:0007591560.020
multicellular organismal agingGO:00102591400.020
cell cycle phase transitionGO:00447701400.020
phagocytosisGO:00069092150.020
negative regulation of mitotic cell cycle phase transitionGO:19019911030.020
dosage compensationGO:0007549160.020
regulation of intracellular signal transductionGO:19025312360.020
g1 s transition of mitotic cell cycleGO:0000082310.020
axon choice point recognitionGO:0016198260.020
macromolecule methylationGO:0043414450.019
gliogenesisGO:0042063800.019
imaginal disc derived wing vein morphogenesisGO:0008586440.019
positive regulation of behaviorGO:0048520190.019
regulation of protein modification processGO:00313991120.019
dna alkylationGO:000630540.019
negative regulation of hormone biosynthetic processGO:003235310.019
negative regulation of apoptotic processGO:0043066630.019
oocyte axis specificationGO:00073091080.019
spermatogenesisGO:00072832000.019
Mouse
eye photoreceptor cell developmentGO:0042462810.019
regulation of molecular functionGO:00650092170.018
developmental maturationGO:00217001720.018
cellular response to organic substanceGO:00713101320.018
male mating behaviorGO:0060179700.018
wound healingGO:0042060750.018
cell cycle comprising mitosis without cytokinesisGO:0033301250.018
molting cycleGO:0042303560.018
regulation of cellular catabolic processGO:00313291570.018
stem cell proliferationGO:0072089880.017
ribonucleoside monophosphate catabolic processGO:0009158390.017
response to ketoneGO:1901654340.017
protein phosphorylationGO:00064681690.017
regulation of muscle cell differentiationGO:005114780.017
protein dna complex subunit organizationGO:0071824860.016
regulation of adult chitin containing cuticle pigmentationGO:0048082130.016
response to alcoholGO:0097305950.016
protein targetingGO:0006605640.016
regulation of cell shapeGO:00083601130.016
segment specificationGO:0007379330.016
anterior posterior axis specification embryoGO:00085951030.016
sensory perceptionGO:00076001960.016
multi organism reproductive behaviorGO:00447051210.016
negative regulation of cell cycle processGO:00109481090.016
gene silencing by mirnaGO:0035195220.016
neuroblast developmentGO:0014019130.016
regulation of phosphatase activityGO:001092130.015
leg disc developmentGO:0035218920.015
organic substance transportGO:00717022570.015
imaginal disc derived leg morphogenesisGO:0007480800.015
positive regulation of multicellular organismal processGO:00512401430.015
interspecies interaction between organismsGO:0044419160.015
positive regulation of multi organism processGO:0043902400.015
regulation of synapse organizationGO:00508071100.015
immune effector processGO:0002252980.015
epithelial cell differentiationGO:00308553220.015
oocyte developmentGO:00485991240.015
photoreceptor cell differentiationGO:00465301700.015
regulation of cellular amino acid metabolic processGO:000652100.015
retina development in camera type eyeGO:006004140.015
lipid biosynthetic processGO:0008610460.015
response to external biotic stimulusGO:00432072930.015
regulation of behaviorGO:0050795750.015
reproductive behaviorGO:00190981220.014
response to biotic stimulusGO:00096072940.014
intracellular signal transductionGO:00355563000.014
reproductive system developmentGO:0061458740.014
regulation of neuron projection developmentGO:0010975690.014
regulation of protein localization to nucleusGO:1900180290.014
skin developmentGO:0043588650.014
positive regulation of protein modification processGO:0031401580.014
positive regulation of neurogenesisGO:0050769410.014
axis specificationGO:00097981670.014
regulation of immune system processGO:00026821760.014
purine ribonucleotide catabolic processGO:00091541090.014
kidney epithelium developmentGO:007207330.013
outflow tract morphogenesisGO:000315140.013
photoreceptor cell developmentGO:0042461960.013
regulation of malpighian tubule diameterGO:003529730.013
heart morphogenesisGO:0003007320.013
stem cell maintenanceGO:0019827670.013
purine ribonucleoside metabolic processGO:00461281270.013
negative regulation of cellular component organizationGO:00511291080.013
mesenchymal cell differentiationGO:004876210.013
regulation of dendrite developmentGO:0050773370.013
regulation of symbiosis encompassing mutualism through parasitismGO:0043903150.013
male courtship behavior veined wing extensionGO:0048065220.013
sarcomere organizationGO:0045214260.013
positive regulation of phosphorus metabolic processGO:00105621390.013
somatic stem cell divisionGO:0048103370.013
histone methylationGO:0016571400.013
protein alkylationGO:0008213430.013
aggressive behaviorGO:0002118630.013
oocyte differentiationGO:00099941450.013
hematopoietic progenitor cell differentiationGO:000224410.012
developmental growthGO:00485892800.012
positive regulation of molecular functionGO:00440931360.012
gastrulationGO:0007369700.012
organonitrogen compound metabolic processGO:19015643180.012
regulation of neuron differentiationGO:00456641030.012
dorsal trunk growth open tracheal systemGO:003500170.012
positive regulation of cell proliferationGO:0008284470.012
positive regulation of translationGO:0045727120.012
neuron remodelingGO:0016322290.012
dna integrity checkpointGO:0031570810.012
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.012
regulation of histone acetylationGO:003506570.012
embryonic hindgut morphogenesisGO:0048619480.012
purine ribonucleoside monophosphate catabolic processGO:0009169380.012
wnt signaling pathwayGO:0016055980.012
brain developmentGO:00074201200.011
bmp signaling pathwayGO:0030509270.011
reproductive structure developmentGO:0048608740.011
pigmentationGO:0043473750.011
carbohydrate derivative metabolic processGO:19011352170.011
atp metabolic processGO:0046034490.011
positive regulation of cell developmentGO:0010720610.011
compound eye photoreceptor developmentGO:0042051780.011
skeletal muscle organ developmentGO:0060538480.011
chemosensory behaviorGO:00076351060.011
female sex differentiationGO:0046660200.011
purine nucleoside monophosphate catabolic processGO:0009128380.011
imaginal disc derived wing margin morphogenesisGO:0008587410.011
regulation of cell proliferationGO:00421271630.011
embryo development ending in birth or egg hatchingGO:00097921520.011
purine nucleoside triphosphate catabolic processGO:00091461080.011
histone h2a ubiquitinationGO:003352220.011
synaptic transmissionGO:00072682880.011
cellular nitrogen compound catabolic processGO:00442701650.011
male genitalia developmentGO:0030539190.011
neuron recognitionGO:00080381010.010
peptidyl lysine methylationGO:0018022160.010
cellular component disassemblyGO:0022411460.010
tube morphogenesisGO:00352391910.010
nucleoside phosphate metabolic processGO:00067531620.010
positive regulation of cell differentiationGO:0045597640.010
nucleoside phosphate catabolic processGO:19012921100.010
rna splicingGO:0008380830.010
gonad morphogenesisGO:003526270.010
female gonad developmentGO:0008585120.010
positive regulation of phosphorylationGO:0042327870.010
meiotic cell cycleGO:00513211710.010

Scm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.036
disease of cellular proliferationDOID:1456600.036
organ system cancerDOID:005068600.036
disease of anatomical entityDOID:700.013