IMP: Integrative Multi-species Prediction

Drosophila melanogaster

123 known processes

pum (Dmel_CG9755)

pumilio

(Aliases: anon-WO0172774.19,CG9763,ovt,Pum,Dmel\CG9755,bem,CG9755,PUM,l(3)01688,ova,fs(3)02003,EP(3)0883,pkl)

Entrez: 41094
FLYBASE: FBgn0003165
UniProtKB: P25822

Process Predictions
Disease Predictions

pum biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regionalization	GO:0003002	416	1.000
axis specification	GO:0009798	167	0.999
oocyte development	GO:0048599	124	0.999
oocyte differentiation	GO:0009994	145	0.999
blastoderm segmentation	GO:0007350	159	0.998
oocyte axis specification	GO:0007309	108	0.995
oocyte microtubule cytoskeleton organization	GO:0016325	35	0.982
segmentation	GO:0035282	207	0.981
cognition	GO:0050890	141	0.972
cell maturation	GO:0048469	144	0.972
memory	GO:0007613	94	0.969
oocyte construction	GO:0007308	112	0.965
embryonic pattern specification	GO:0009880	174	0.960
learning or memory	GO:0007611	141	0.936
wing disc morphogenesis	GO:0007472	344	0.932
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.924
regulation of pole plasm oskar mrna localization	GO:0007317	27	0.922
regulation of multicellular organismal development	GO:2000026	414	0.916
regulation of transport	GO:0051049	181	0.911
germarium derived egg chamber formation	GO:0007293	101	0.889
anterior posterior pattern specification	GO:0009952	136	0.870
oocyte anterior posterior axis specification	GO:0007314	72	0.868
embryonic morphogenesis	GO:0048598	206	0.864
anterior posterior axis specification	GO:0009948	109	0.815
pole plasm mrna localization	GO:0019094	49	0.815
embryonic axis specification	GO:0000578	107	0.806
axon guidance	GO:0007411	233	0.803
male gamete generation	GO:0048232	201	0.795	Worm
vesicle mediated transport	GO:0016192	381	0.736
single organism cellular localization	GO:1902580	180	0.735
immune system process	GO:0002376	347	0.732
oocyte microtubule cytoskeleton polarization	GO:0008103	22	0.718
tripartite regional subdivision	GO:0007351	103	0.703
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.697
anterior posterior axis specification embryo	GO:0008595	103	0.682
neuromuscular junction development	GO:0007528	149	0.680
axon development	GO:0061564	297	0.664
regulation of localization	GO:0032879	275	0.664
determination of adult lifespan	GO:0008340	137	0.662
spindle organization	GO:0007051	253	0.653
pole plasm rna localization	GO:0007316	52	0.640
embryo development ending in birth or egg hatching	GO:0009792	152	0.636
dorsal appendage formation	GO:0046843	47	0.621
axonogenesis	GO:0007409	290	0.619
oocyte localization involved in germarium derived egg chamber formation	GO:0030720	12	0.595
protein complex assembly	GO:0006461	200	0.590
mushroom body development	GO:0016319	70	0.585
establishment of localization in cell	GO:0051649	402	0.584
regulation of cellular component biogenesis	GO:0044087	201	0.569
spermatogenesis	GO:0007283	200	0.561	Worm
germarium derived oocyte fate determination	GO:0007294	26	0.556
posttranscriptional regulation of gene expression	GO:0010608	145	0.548
protein import into nucleus	GO:0006606	51	0.547
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.541
cellular macromolecule localization	GO:0070727	220	0.538	Yeast
immune response activating signal transduction	GO:0002757	2	0.534
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.531
signal release	GO:0023061	49	0.506
regulation of cell differentiation	GO:0045595	302	0.504
imaginal disc derived appendage development	GO:0048737	399	0.502
regulation of embryonic development	GO:0045995	68	0.501
response to organic substance	GO:0010033	284	0.500
actin cytoskeleton organization	GO:0030036	206	0.480
regulation of cellular localization	GO:0060341	136	0.468
chorion containing eggshell formation	GO:0007304	105	0.462
actin filament based process	GO:0030029	220	0.451
oocyte dorsal ventral axis specification	GO:0007310	34	0.451
pole plasm assembly	GO:0007315	61	0.448
mitotic spindle organization	GO:0007052	220	0.448
synaptic growth at neuromuscular junction	GO:0051124	119	0.447
intracellular transport	GO:0046907	228	0.444
developmental growth	GO:0048589	280	0.435
growth	GO:0040007	359	0.431
multicellular organism growth	GO:0035264	46	0.429
positive regulation of rna biosynthetic process	GO:1902680	266	0.428
ribonucleoprotein complex subunit organization	GO:0071826	28	0.421	Mouse
dorsal ventral pattern formation	GO:0009953	133	0.418
positive regulation of cellular component biogenesis	GO:0044089	80	0.416
protein phosphorylation	GO:0006468	169	0.408
synapse assembly	GO:0007416	143	0.396
establishment of protein localization	GO:0045184	163	0.384
imaginal disc derived wing morphogenesis	GO:0007476	337	0.382
negative regulation of multicellular organismal process	GO:0051241	142	0.381	Worm
tissue morphogenesis	GO:0048729	297	0.369
neurological system process	GO:0050877	358	0.368
proteolysis	GO:0006508	192	0.360
regulation of oocyte development	GO:0060281	27	0.350
eggshell formation	GO:0030703	105	0.347
positive regulation of cellular biosynthetic process	GO:0031328	316	0.341
secretion	GO:0046903	109	0.339
regulation of protein metabolic process	GO:0051246	256	0.338
motor neuron axon guidance	GO:0008045	58	0.330
endocytosis	GO:0006897	310	0.327
regulation of phosphate metabolic process	GO:0019220	210	0.322	Worm
regulation of molecular function	GO:0065009	217	0.320
synapse organization	GO:0050808	196	0.318
developmental maturation	GO:0021700	172	0.314
positive regulation of gene expression	GO:0010628	290	0.312
neuron projection guidance	GO:0097485	241	0.301
epithelial cell differentiation	GO:0030855	322	0.295
chemotaxis	GO:0006935	249	0.294
central nervous system development	GO:0007417	201	0.293
actin filament bundle assembly	GO:0051017	26	0.291
taxis	GO:0042330	304	0.283
muscle structure development	GO:0061061	224	0.282
regulation of growth	GO:0040008	233	0.280
cell adhesion	GO:0007155	136	0.280
negative regulation of response to stimulus	GO:0048585	258	0.275
response to alcohol	GO:0097305	95	0.263
morphogenesis of embryonic epithelium	GO:0016331	94	0.258
post embryonic appendage morphogenesis	GO:0035120	385	0.251
embryonic development via the syncytial blastoderm	GO:0001700	148	0.242
actin polymerization or depolymerization	GO:0008154	31	0.240
eggshell chorion assembly	GO:0007306	66	0.237
localization of cell	GO:0051674	257	0.233
dorsal ventral axis specification ovarian follicular epithelium	GO:0008069	13	0.233
rna localization	GO:0006403	115	0.232	Yeast
germarium derived female germ line cyst encapsulation	GO:0030708	8	0.232
appendage development	GO:0048736	401	0.231
regulation of cell shape	GO:0008360	113	0.226
dorsal ventral axis specification	GO:0009950	66	0.222
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.221
cytokinesis	GO:0000910	90	0.220
apoptotic process	GO:0006915	159	0.216
carbohydrate derivative metabolic process	GO:1901135	217	0.203
regulation of immune system process	GO:0002682	176	0.203
cellular protein modification process	GO:0006464	438	0.202
pole plasm oskar mrna localization	GO:0045451	46	0.200
response to ecdysone	GO:0035075	34	0.198
regulation of cellular protein metabolic process	GO:0032268	243	0.196
eye photoreceptor cell differentiation	GO:0001754	145	0.196
regulation of apoptotic process	GO:0042981	130	0.195
brain development	GO:0007420	120	0.193
hemopoiesis	GO:0030097	46	0.188
single organism behavior	GO:0044708	391	0.186
long term memory	GO:0007616	62	0.186
response to bacterium	GO:0009617	198	0.179
positive regulation of cellular component organization	GO:0051130	156	0.177
cellular response to chemical stimulus	GO:0070887	199	0.175
gland development	GO:0048732	191	0.175
protein localization to nucleus	GO:0034504	55	0.175
actin filament organization	GO:0007015	126	0.172
protein complex biogenesis	GO:0070271	201	0.172
regulation of protein transport	GO:0051223	57	0.169
positive regulation of organelle organization	GO:0010638	65	0.166
dorsal closure	GO:0007391	79	0.164
skin development	GO:0043588	65	0.163
regulation of defense response	GO:0031347	102	0.162
reproductive behavior	GO:0019098	122	0.161
gonad development	GO:0008406	50	0.160
tube development	GO:0035295	244	0.160
organelle assembly	GO:0070925	198	0.159	Mouse
nucleobase containing compound catabolic process	GO:0034655	165	0.158	Yeast
cellular response to organic substance	GO:0071310	132	0.155
establishment of monopolar cell polarity	GO:0061162	15	0.154
positive regulation of macromolecule metabolic process	GO:0010604	405	0.151
head development	GO:0060322	135	0.150
regulation of cytoplasmic transport	GO:1903649	47	0.150
actin filament bundle organization	GO:0061572	28	0.150
regulation of gene silencing	GO:0060968	63	0.150
regulation of embryonic cell shape	GO:0016476	30	0.148
positive regulation of transcription dna templated	GO:0045893	266	0.145
regulation of intracellular protein transport	GO:0033157	46	0.143
reproductive system development	GO:0061458	74	0.139
phagocytosis	GO:0006909	215	0.138
forebrain development	GO:0030900	2	0.137
chaeta development	GO:0022416	97	0.136
multicellular organismal reproductive behavior	GO:0033057	110	0.136
development of primary sexual characteristics	GO:0045137	50	0.135
tube morphogenesis	GO:0035239	191	0.130
translation	GO:0006412	69	0.130
negative regulation of cell communication	GO:0010648	223	0.127
cellular catabolic process	GO:0044248	372	0.127	Yeast
short term memory	GO:0007614	19	0.126
cytoplasmic transport	GO:0016482	130	0.126
eye development	GO:0001654	323	0.124
catabolic process	GO:0009056	409	0.122	Yeast
regulation of protein kinase activity	GO:0045859	51	0.121
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.120
regulation of protein localization	GO:0032880	76	0.118
establishment or maintenance of cell polarity	GO:0007163	167	0.118
ovarian fusome organization	GO:0030723	11	0.116
positive regulation of response to stimulus	GO:0048584	323	0.115
protein localization	GO:0008104	284	0.111
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.111
morphogenesis of an epithelium	GO:0002009	276	0.110
neurotransmitter transport	GO:0006836	37	0.110
multicellular organismal aging	GO:0010259	140	0.109
secretion by cell	GO:0032940	101	0.109
organic substance catabolic process	GO:1901575	308	0.108	Yeast
organic substance transport	GO:0071702	257	0.107
negative regulation of developmental process	GO:0051093	201	0.107	Worm
positive regulation of biosynthetic process	GO:0009891	316	0.107
positive regulation of molecular function	GO:0044093	136	0.105
cellular response to oxygen containing compound	GO:1901701	79	0.105
germ cell migration	GO:0008354	43	0.104
positive regulation of cell migration	GO:0030335	2	0.103
regulation of intracellular transport	GO:0032386	64	0.103
positive regulation of rna metabolic process	GO:0051254	271	0.102
regulation of establishment of protein localization	GO:0070201	61	0.101
regulation of multi organism process	GO:0043900	131	0.099
chromosome organization	GO:0051276	360	0.099
intracellular signal transduction	GO:0035556	300	0.096	Worm
germarium derived female germ line cyst formation	GO:0030727	42	0.095
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.094
oocyte nucleus localization involved in oocyte dorsal ventral axis specification	GO:0051663	12	0.094
regulation of cell development	GO:0060284	215	0.093
photoreceptor cell differentiation	GO:0046530	170	0.093
regulation of protein modification process	GO:0031399	112	0.092
regulation of response to stress	GO:0080134	200	0.091
cellular component assembly involved in morphogenesis	GO:0010927	151	0.091
response to ethanol	GO:0045471	59	0.089
single organism intracellular transport	GO:1902582	207	0.089
multi organism behavior	GO:0051705	175	0.088
telencephalon development	GO:0021537	2	0.087
eye morphogenesis	GO:0048592	260	0.086
hemocyte differentiation	GO:0042386	38	0.086
cell fate determination	GO:0001709	91	0.084
response to abiotic stimulus	GO:0009628	341	0.083
sensory organ morphogenesis	GO:0090596	260	0.083
regulation of phosphorus metabolic process	GO:0051174	210	0.081	Worm
regulation of hydrolase activity	GO:0051336	97	0.080
response to wounding	GO:0009611	94	0.077
establishment or maintenance of cytoskeleton polarity	GO:0030952	44	0.076
blood circulation	GO:0008015	26	0.076
response to external biotic stimulus	GO:0043207	293	0.075
regulation of compound eye cone cell fate specification	GO:0042682	4	0.075
response to organonitrogen compound	GO:0010243	75	0.074
macromolecular complex assembly	GO:0065003	256	0.074	Mouse
posttranscriptional gene silencing by rna	GO:0035194	45	0.073
aromatic compound catabolic process	GO:0019439	166	0.072	Yeast
aging	GO:0007568	143	0.072
fertilization	GO:0009566	26	0.071
body morphogenesis	GO:0010171	2	0.070
regulation of membrane depolarization	GO:0003254	1	0.070
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.069
negative regulation of cellular metabolic process	GO:0031324	382	0.069	Worm
multi organism reproductive behavior	GO:0044705	121	0.068
pole cell development	GO:0007277	26	0.068
positive regulation of i kappab kinase nf kappab signaling	GO:0043123	1	0.068
regulation of nervous system development	GO:0051960	248	0.068
sensory perception	GO:0007600	196	0.067
negative regulation of cellular protein metabolic process	GO:0032269	85	0.067
intracellular protein transport	GO:0006886	104	0.067
biological adhesion	GO:0022610	138	0.066
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.065
immune response regulating signaling pathway	GO:0002764	2	0.064
regulation of anatomical structure morphogenesis	GO:0022603	242	0.064
negative regulation of signaling	GO:0023057	219	0.063
response to other organism	GO:0051707	293	0.063
instar larval development	GO:0002168	55	0.063
protein transport	GO:0015031	155	0.063
regulation of phosphatase activity	GO:0010921	3	0.063
regulation of catalytic activity	GO:0050790	185	0.062
response to nitrogen compound	GO:1901698	90	0.062
response to endogenous stimulus	GO:0009719	119	0.062
regulation of cell death	GO:0010941	173	0.061
hematopoietic or lymphoid organ development	GO:0048534	57	0.060
endomembrane system organization	GO:0010256	119	0.060
regulation of cell cycle	GO:0051726	291	0.059	Worm
muscle contraction	GO:0006936	13	0.059
protein localization to organelle	GO:0033365	82	0.058
negative regulation of transcription dna templated	GO:0045892	237	0.058
single organism nuclear import	GO:1902593	51	0.058
posttranscriptional gene silencing	GO:0016441	46	0.057
cellular protein localization	GO:0034613	160	0.057
positive regulation of signaling	GO:0023056	243	0.057
protein import	GO:0017038	55	0.057
learning	GO:0007612	75	0.056
negative regulation of molecular function	GO:0044092	51	0.056
response to biotic stimulus	GO:0009607	294	0.056
oocyte maturation	GO:0001556	3	0.056
cellular response to abiotic stimulus	GO:0071214	58	0.055
positive regulation of multicellular organismal process	GO:0051240	143	0.055
regulation of meiosis	GO:0040020	3	0.055	Worm
actin filament polymerization	GO:0030041	27	0.054
single organism cell adhesion	GO:0098602	47	0.054
maintenance of location	GO:0051235	73	0.054
positive regulation of developmental growth	GO:0048639	62	0.053
positive regulation of cell differentiation	GO:0045597	64	0.053
camera type eye development	GO:0043010	4	0.053
regulation of cellular amine metabolic process	GO:0033238	3	0.053
protein modification process	GO:0036211	438	0.052
compound eye photoreceptor fate commitment	GO:0001752	36	0.051
negative regulation of mitotic anaphase promoting complex activity	GO:0060564	2	0.051
regulation of actin cytoskeleton organization	GO:0032956	42	0.051
organonitrogen compound biosynthetic process	GO:1901566	117	0.051
cuticle development	GO:0042335	86	0.050
negative regulation of protein metabolic process	GO:0051248	85	0.050
regulation of neuroblast proliferation	GO:1902692	34	0.050
regulation of cell fate commitment	GO:0010453	29	0.049
stem cell proliferation	GO:0072089	88	0.049
appendage morphogenesis	GO:0035107	397	0.048
regulation of nucleocytoplasmic transport	GO:0046822	35	0.048
genitalia development	GO:0048806	26	0.048
negative regulation of protein processing	GO:0010955	31	0.048
regulation of system process	GO:0044057	36	0.047
ribose phosphate metabolic process	GO:0019693	145	0.047
regulation of secretion by cell	GO:1903530	39	0.047
nuclear transport	GO:0051169	72	0.046
larval development	GO:0002164	104	0.046	Worm
regulation of developmental growth	GO:0048638	174	0.046
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.045
stem cell division	GO:0017145	69	0.045
reproductive structure development	GO:0048608	74	0.045
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.045
nuclear import	GO:0051170	51	0.045
regulation of response to wounding	GO:1903034	19	0.045
cellular response to endogenous stimulus	GO:0071495	80	0.044
cytoplasmic mrna processing body assembly	GO:0033962	10	0.044
protein catabolic process	GO:0030163	101	0.044
regulation of protein localization to nucleus	GO:1900180	29	0.044
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.043
meiotic cell cycle	GO:0051321	171	0.043	Worm
neural precursor cell proliferation	GO:0061351	75	0.043
positive regulation of protein complex assembly	GO:0031334	22	0.043
axon choice point recognition	GO:0016198	26	0.043
positive regulation of defense response	GO:0031349	59	0.042
cell projection assembly	GO:0030031	94	0.041
r7 cell differentiation	GO:0045466	43	0.041
negative regulation of epithelial cell migration	GO:0010633	1	0.041
olfactory learning	GO:0008355	56	0.041
muscle cell differentiation	GO:0042692	103	0.041
epithelial cell migration	GO:0010631	148	0.040
positive regulation of protein modification process	GO:0031401	58	0.040
morphogenesis of follicular epithelium	GO:0016333	36	0.040
organelle fission	GO:0048285	340	0.040	Worm
gene silencing	GO:0016458	138	0.040
pole plasm protein localization	GO:0007318	10	0.040
regulation of immune response	GO:0050776	118	0.040
death	GO:0016265	284	0.039
olfactory behavior	GO:0042048	97	0.039
cell recognition	GO:0008037	102	0.039
positive regulation of immune response	GO:0050778	63	0.039
cell death	GO:0008219	279	0.039
positive regulation of cytoskeleton organization	GO:0051495	21	0.039
locomotory behavior	GO:0007626	176	0.039
programmed cell death	GO:0012501	257	0.039
regulation of tube architecture open tracheal system	GO:0035152	68	0.038
cell junction organization	GO:0034330	57	0.038
establishment of vesicle localization	GO:0051650	51	0.038
regulation of neurotransmitter levels	GO:0001505	38	0.037
immune system development	GO:0002520	57	0.037
single organism membrane organization	GO:0044802	93	0.037
regulation of cell junction assembly	GO:1901888	2	0.037
regulation of cell motility	GO:2000145	23	0.037
cell type specific apoptotic process	GO:0097285	38	0.037
transcription from rna polymerase ii promoter	GO:0006366	368	0.037
negative regulation of cell cycle	GO:0045786	116	0.036
convergent extension involved in gastrulation	GO:0060027	2	0.036
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.036
regulation of cell migration	GO:0030334	22	0.036
organophosphate metabolic process	GO:0019637	195	0.036
regulation of cellular ketone metabolic process	GO:0010565	3	0.035
protein targeting	GO:0006605	64	0.035
positive regulation of neurogenesis	GO:0050769	41	0.035
meiotic chromosome segregation	GO:0045132	59	0.035
i kappab kinase nf kappab signaling	GO:0007249	6	0.035
pattern recognition receptor signaling pathway	GO:0002221	2	0.035
neuron recognition	GO:0008038	101	0.034
cellular amine metabolic process	GO:0044106	12	0.034
cytoplasmic transport nurse cell to oocyte	GO:0007303	12	0.034
cellular response to organic cyclic compound	GO:0071407	32	0.034
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.034
actomyosin structure organization	GO:0031032	56	0.033
regulation of cytoskeleton organization	GO:0051493	89	0.033
wound healing	GO:0042060	75	0.033
oviposition	GO:0018991	19	0.033
regulation of reproductive process	GO:2000241	54	0.033
positive regulation of transport	GO:0051050	92	0.033
mesoderm development	GO:0007498	78	0.033
response to organic cyclic compound	GO:0014070	89	0.032
protein processing	GO:0016485	68	0.032
regulation of humoral immune response	GO:0002920	51	0.032
cell migration	GO:0016477	238	0.032
female germ line cyst encapsulation	GO:0048139	8	0.032
positive regulation of protein metabolic process	GO:0051247	128	0.032
response to heat	GO:0009408	63	0.031
neurotransmitter secretion	GO:0007269	35	0.031
regulation of gene expression epigenetic	GO:0040029	128	0.031
purine nucleotide metabolic process	GO:0006163	146	0.031
nuclear axial expansion	GO:0035191	3	0.031
positive regulation of cell motility	GO:2000147	3	0.031
negative regulation of translation	GO:0017148	28	0.031
positive regulation of phosphate metabolic process	GO:0045937	139	0.031
response to temperature stimulus	GO:0009266	106	0.030
organonitrogen compound metabolic process	GO:1901564	318	0.029
amine metabolic process	GO:0009308	12	0.029
negative regulation of immune system process	GO:0002683	50	0.028
chemosensory behavior	GO:0007635	106	0.028
multi multicellular organism process	GO:0044706	123	0.028
heart process	GO:0003015	37	0.028
positive regulation of cellular amine metabolic process	GO:0033240	0	0.028
circulatory system process	GO:0003013	37	0.028
purine ribonucleoside metabolic process	GO:0046128	127	0.028
negative regulation of cell proliferation	GO:0008285	69	0.028
homeostatic process	GO:0042592	199	0.028
regulation of response to external stimulus	GO:0032101	115	0.028
digestive tract development	GO:0048565	149	0.027
small molecule metabolic process	GO:0044281	305	0.027
hemocyte migration	GO:0035099	19	0.026
immune response	GO:0006955	246	0.026
head involution	GO:0008258	35	0.026
photoreceptor cell development	GO:0042461	96	0.026
positive regulation of signal transduction	GO:0009967	223	0.026
maintenance of protein location	GO:0045185	28	0.026
organelle localization	GO:0051640	148	0.026	Yeast
regulation of cell adhesion	GO:0030155	27	0.026
epidermal cell differentiation	GO:0009913	51	0.026
chromosome condensation	GO:0030261	41	0.026
regulation of cell cell adhesion	GO:0022407	21	0.026
nucleotide catabolic process	GO:0009166	109	0.026
stress granule disassembly	GO:0035617	1	0.026
protein targeting to nucleus	GO:0044744	51	0.026
membrane organization	GO:0061024	112	0.025
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.025
nuclear division	GO:0000280	332	0.024	Worm
negative regulation of programmed cell death	GO:0043069	72	0.024
response to mechanical stimulus	GO:0009612	28	0.024
regulation of transcription factor import into nucleus	GO:0042990	22	0.024
regulation of anatomical structure size	GO:0090066	163	0.024
purine ribonucleotide metabolic process	GO:0009150	145	0.024
nucleocytoplasmic transport	GO:0006913	72	0.024
muscle cell development	GO:0055001	50	0.023
dorsal closure leading edge cell differentiation	GO:0046663	2	0.023
salivary gland morphogenesis	GO:0007435	145	0.023
ribonucleoprotein complex assembly	GO:0022618	23	0.023	Mouse
negative regulation of gene expression	GO:0010629	387	0.023
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.023
neuroblast proliferation	GO:0007405	74	0.023
negative regulation of biosynthetic process	GO:0009890	277	0.023
regulation of mitotic cell cycle	GO:0007346	190	0.023
regulation of translation	GO:0006417	56	0.022
regulation of neural precursor cell proliferation	GO:2000177	35	0.022
positive regulation of nervous system development	GO:0051962	69	0.022
antimicrobial peptide biosynthetic process	GO:0002777	38	0.022
response to oxygen containing compound	GO:1901700	200	0.022
regulation of secretion	GO:0051046	44	0.021
regulation of reactive oxygen species biosynthetic process	GO:1903426	0	0.021
positive regulation of exocytosis	GO:0045921	4	0.021
female germ line cyst formation	GO:0048135	42	0.021
activation of immune response	GO:0002253	5	0.021
regulation of centriole replication	GO:0046599	2	0.021
positive regulation of cell communication	GO:0010647	250	0.021
regulation of cell cycle phase transition	GO:1901987	130	0.020
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	4	0.020
regulation of neurotransmitter secretion	GO:0046928	14	0.020
cell cell junction organization	GO:0045216	55	0.020
positive regulation of protein transport	GO:0051222	37	0.020
meiotic chromosome condensation	GO:0010032	3	0.020
chromosome segregation	GO:0007059	157	0.020
epidermis development	GO:0008544	65	0.020
rna interference	GO:0016246	27	0.020
peptidyl threonine phosphorylation	GO:0018107	2	0.020
establishment of protein localization to organelle	GO:0072594	62	0.020
larval lymph gland hemocyte differentiation	GO:0035168	11	0.020
negative regulation of catalytic activity	GO:0043086	42	0.020
response to decreased oxygen levels	GO:0036293	58	0.020
generation of precursor metabolites and energy	GO:0006091	42	0.019	Yeast
regulation of organelle organization	GO:0033043	196	0.019	Worm
stress activated protein kinase signaling cascade	GO:0031098	55	0.019
digestive system development	GO:0055123	149	0.019
oocyte morphogenesis	GO:0048601	3	0.019
regulation of cell cycle process	GO:0010564	181	0.019	Worm
response to drug	GO:0042493	17	0.019
cellular response to organonitrogen compound	GO:0071417	36	0.019
cellular nitrogen compound catabolic process	GO:0044270	165	0.019	Yeast
rna processing	GO:0006396	147	0.019
regulation of dendrite morphogenesis	GO:0048814	28	0.019
response to lipopolysaccharide	GO:0032496	4	0.019
regulation of exocytosis	GO:0017157	6	0.019
ovarian follicle cell stalk formation	GO:0030713	17	0.018
establishment of cell polarity	GO:0030010	40	0.018
urogenital system development	GO:0001655	72	0.018
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.018
regulation of proteolysis	GO:0030162	87	0.018
kidney development	GO:0001822	3	0.018
cell division	GO:0051301	248	0.018	Worm
ribonucleoprotein complex biogenesis	GO:0022613	31	0.018	Mouse
epithelial cell development	GO:0002064	274	0.018
regulation of protein maturation	GO:1903317	32	0.018
lipid localization	GO:0010876	54	0.018
cardiac cell fate commitment	GO:0060911	17	0.018
germarium derived oocyte differentiation	GO:0030706	29	0.018
regulation of cellular component movement	GO:0051270	42	0.018
regulation of transferase activity	GO:0051338	58	0.018
positive regulation of cell cycle	GO:0045787	43	0.018
adherens junction organization	GO:0034332	27	0.017
post embryonic hemopoiesis	GO:0035166	17	0.017
regulation of wnt signaling pathway	GO:0030111	68	0.017
dendrite regeneration	GO:0031104	2	0.017
regulation of actin filament length	GO:0030832	27	0.017
cellular response to molecule of bacterial origin	GO:0071219	3	0.017
lysosome localization	GO:0032418	1	0.017

pum disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
organ system cancer	DOID:0050686	0.021
cancer	DOID:162	0.021
disease of cellular proliferation	DOID:14566	0.021

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