Drosophila melanogaster

122 known processes

hkb (Dmel_CG9768)

huckebein

(Aliases: 5953,gurt,Dmel\CG9768,CG9768,Hkb,anon-82B3,HKB)

hkb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
digestive tract morphogenesisGO:00485461270.987
digestive system developmentGO:00551231490.984
digestive tract developmentGO:00485651490.982
axonogenesisGO:00074092900.963
malpighian tubule morphogenesisGO:0007443440.961
negative regulation of transcription dna templatedGO:00458922370.954
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.953
tube developmentGO:00352952440.941
central nervous system developmentGO:00074172010.932
tissue morphogenesisGO:00487292970.928
embryonic pattern specificationGO:00098801740.918
axon developmentGO:00615642970.910
negative regulation of gene expressionGO:00106293870.908
neuron projection guidanceGO:00974852410.903
renal system developmentGO:0072001720.902
tube morphogenesisGO:00352391910.892
regulation of multicellular organismal developmentGO:20000264140.888
urogenital system developmentGO:0001655720.880
renal tubule developmentGO:0061326640.877
dendrite developmentGO:00163582040.866
organ formationGO:0048645390.858
positive regulation of nucleic acid templated transcriptionGO:19035082660.857
negative regulation of nucleic acid templated transcriptionGO:19035072400.847
head developmentGO:00603221350.844
negative regulation of rna biosynthetic processGO:19026792400.840
regionalizationGO:00030024160.819
positive regulation of rna biosynthetic processGO:19026802660.818
exocrine system developmentGO:00352721620.816
epithelial cell migrationGO:00106311480.815
embryonic hindgut morphogenesisGO:0048619480.805
salivary gland developmentGO:00074311620.803
cell migrationGO:00164772380.796
positive regulation of transcription dna templatedGO:00458932660.780
blastoderm segmentationGO:00073501590.779
malpighian tubule developmentGO:0072002640.779
brain developmentGO:00074201200.777
regulation of cell differentiationGO:00455953020.767
gland morphogenesisGO:00226121450.762
hindgut morphogenesisGO:0007442580.756
regulation of transcription from rna polymerase ii promoterGO:00063573780.748
morphogenesis of an epitheliumGO:00020092760.727
taxisGO:00423303040.726
positive regulation of gene expressionGO:00106282900.714
neuroblast differentiationGO:0014016290.711
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.711
ameboidal type cell migrationGO:00016671510.708
positive regulation of macromolecule biosynthetic processGO:00105572830.706
negative regulation of macromolecule biosynthetic processGO:00105582700.700
heart developmentGO:0007507820.698
positive regulation of rna metabolic processGO:00512542710.693
epithelial tube morphogenesisGO:0060562880.681
axon guidanceGO:00074112330.681
columnar cuboidal epithelial cell differentiationGO:00020652560.679
localization of cellGO:00516742570.677
segmentationGO:00352822070.669
chemotaxisGO:00069352490.660
negative regulation of cellular biosynthetic processGO:00313272770.655
positive regulation of cellular biosynthetic processGO:00313283160.644
negative regulation of nitrogen compound metabolic processGO:00511722650.638
neuron recognitionGO:00080381010.623
dendrite morphogenesisGO:00488131990.610
respiratory system developmentGO:00605412130.608
transcription from rna polymerase ii promoterGO:00063663680.603
hindgut developmentGO:0061525580.588
gland developmentGO:00487321910.588
cell motilityGO:00488702510.582
renal tubule morphogenesisGO:0061333440.569
negative regulation of biosynthetic processGO:00098902770.565
positive regulation of nitrogen compound metabolic processGO:00511733540.558
positive regulation of biosynthetic processGO:00098913160.552
regulation of nervous system developmentGO:00519602480.541
regulation of growthGO:00400082330.538
multi organism reproductive behaviorGO:00447051210.538
biological adhesionGO:00226101380.511
embryonic morphogenesisGO:00485982060.509
growthGO:00400073590.499
response to external biotic stimulusGO:00432072930.496
multicellular organismal reproductive behaviorGO:00330571100.446
synaptic growth at neuromuscular junctionGO:00511241190.439
eye developmentGO:00016543230.438
motor neuron axon guidanceGO:0008045580.435
circulatory system developmentGO:0072359820.434
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.434
forebrain developmentGO:003090020.432
developmental growthGO:00485892800.431
positive regulation of macromolecule metabolic processGO:00106044050.428
negative regulation of cellular metabolic processGO:00313243820.424
ovarian follicle cell migrationGO:00072971210.423
open tracheal system developmentGO:00074242040.409
reproductive system developmentGO:0061458740.396
regulation of neurogenesisGO:00507671580.392
regulation of developmental growthGO:00486381740.384
negative regulation of cell communicationGO:00106482230.379
negative regulation of cell differentiationGO:00455961430.379
regulation of organ morphogenesisGO:2000027780.378
cardioblast differentiationGO:0010002200.376
kidney epithelium developmentGO:007207330.359
stem cell differentiationGO:00488631170.355
salivary gland morphogenesisGO:00074351450.354
compound eye photoreceptor cell differentiationGO:00017511400.352
mesodermal cell migrationGO:000807870.347
negative regulation of rna metabolic processGO:00512532510.346
immune system processGO:00023763470.343
telencephalon developmentGO:002153720.333
regulation of cell developmentGO:00602842150.331
epithelial cell differentiationGO:00308553220.323
mesoderm developmentGO:0007498780.320
negative regulation of nucleobase containing compound metabolic processGO:00459342610.318
regulation of heart morphogenesisGO:200082630.316
dna metabolic processGO:00062592270.315
positive regulation of cellular component organizationGO:00511301560.311
epithelial cell migration open tracheal systemGO:0007427320.302
tissue migrationGO:00901301550.296
regulation of anatomical structure morphogenesisGO:00226032420.287
germ cell migrationGO:0008354430.279
mesoderm formationGO:0001707210.277
mesenchyme developmentGO:006048590.275
apoptotic processGO:00069151590.275
negative regulation of multicellular organismal processGO:00512411420.267
cell fate commitment involved in formation of primary germ layerGO:0060795100.264
border follicle cell migrationGO:00072981130.255
anterior posterior pattern specificationGO:00099521360.254
regulation of response to stressGO:00801342000.253
negative regulation of growthGO:0045926840.253
deathGO:00162652840.249
positive regulation of nucleobase containing compound metabolic processGO:00459353320.244
morphogenesis of embryonic epitheliumGO:0016331940.236
developmental programmed cell deathGO:00106231380.235
mesodermal cell differentiationGO:004833370.233
epithelial cell developmentGO:00020642740.229
cell fate specificationGO:0001708710.229
skin developmentGO:0043588650.228
cell deathGO:00082192790.225
regulation of neuron differentiationGO:00456641030.224
embryonic development via the syncytial blastodermGO:00017001480.224
head segmentationGO:0035287130.217
regulation of anatomical structure sizeGO:00900661630.215
columnar cuboidal epithelial cell developmentGO:00020662490.211
gliogenesisGO:0042063800.211
eye photoreceptor cell fate commitmentGO:0042706370.211
gastrulationGO:0007369700.210
muscle structure developmentGO:00610612240.209
genital disc developmentGO:0035215440.208
development of primary sexual characteristicsGO:0045137500.205
appendage morphogenesisGO:00351073970.200
cardiovascular system developmentGO:0072358820.198
neuroblast fate commitmentGO:0014017190.197
mesodermal cell fate specificationGO:000750120.197
negative regulation of nervous system developmentGO:0051961920.194
regulation of cell deathGO:00109411730.191
neuron fate commitmentGO:0048663500.190
mesodermal cell fate commitmentGO:000171070.185
negative regulation of cell cycleGO:00457861160.184
cell proliferationGO:00082832990.183
torso signaling pathwayGO:0008293210.182
positive regulation of developmental processGO:00510941430.180
axon choice point recognitionGO:0016198260.180
eye photoreceptor cell differentiationGO:00017541450.180
dorsal ventral pattern formationGO:00099531330.175
reproductive behaviorGO:00190981220.174
synapse organizationGO:00508081960.172
regulation of cell fate commitmentGO:0010453290.167
gonad developmentGO:0008406500.163
neuron fate determinationGO:004866410.163
cardioblast cell fate commitmentGO:0042684140.161
cell cycle dna replicationGO:0044786230.160
embryo development ending in birth or egg hatchingGO:00097921520.159
sex differentiationGO:0007548810.159
cell adhesionGO:00071551360.158
regulation of programmed cell deathGO:00430671520.156
positive regulation of neurogenesisGO:0050769410.156
compound eye developmentGO:00487493070.156
mesoderm morphogenesisGO:0048332220.153
regulation of cell morphogenesisGO:00226041630.151
negative regulation of cell deathGO:0060548810.151
positive regulation of response to stimulusGO:00485843230.148
regulation of apoptotic processGO:00429811300.145
regulation of organelle organizationGO:00330431960.144
oocyte differentiationGO:00099941450.142
reproductive structure developmentGO:0048608740.142
cardiac cell fate commitmentGO:0060911170.139
epidermis developmentGO:0008544650.137
organic hydroxy compound metabolic processGO:1901615830.135
sensory organ morphogenesisGO:00905962600.131
nephrocyte differentiationGO:0061319120.130
compound eye morphogenesisGO:00017452490.129
embryonic heart tube developmentGO:0035050220.128
regulation of embryonic developmentGO:0045995680.126
negative regulation of signal transductionGO:00099682060.126
spiracle morphogenesis open tracheal systemGO:0035277220.125
negative regulation of signalingGO:00230572190.125
eye morphogenesisGO:00485922600.124
larval developmentGO:00021641040.123
kidney developmentGO:000182230.121
mating behaviorGO:00076171060.119
axon midline choice point recognitionGO:0016199260.118
protein localizationGO:00081042840.117
negative regulation of developmental growthGO:0048640640.117
regulation of dendrite developmentGO:0050773370.116
negative regulation of apoptotic processGO:0043066630.114
cell cell signaling involved in cell fate commitmentGO:00451682100.114
synapse assemblyGO:00074161430.113
positive regulation of cell developmentGO:0010720610.112
regulation of cell proliferationGO:00421271630.112
cardiocyte differentiationGO:0035051290.112
single organism cell adhesionGO:0098602470.109
stem cell fate commitmentGO:0048865250.109
nephron tubule morphogenesisGO:007207830.108
retinal ganglion cell axon guidanceGO:0031290120.108
response to other organismGO:00517072930.108
cellular ketone metabolic processGO:0042180240.107
cell maturationGO:00484691440.107
regulation of immune system processGO:00026821760.106
dorsal closureGO:0007391790.105
stem cell developmentGO:0048864790.104
programmed cell deathGO:00125012570.103
regulation of cellular amine metabolic processGO:003323830.101
hematopoietic or lymphoid organ developmentGO:0048534570.101
neuroblast developmentGO:0014019130.101
dna endoreduplicationGO:0042023220.101
bmp signaling pathwayGO:0030509270.099
negative regulation of developmental processGO:00510932010.098
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.098
regulation of cell growthGO:0001558430.097
multi multicellular organism processGO:00447061230.097
immune system developmentGO:0002520570.096
positive regulation of programmed cell deathGO:0043068620.096
neuroblast divisionGO:0055057350.095
histolysisGO:00075591020.094
body morphogenesisGO:001017120.094
formation of primary germ layerGO:0001704240.093
cellular response to chemical stimulusGO:00708871990.092
anterior posterior axis specificationGO:00099481090.091
heart morphogenesisGO:0003007320.089
regulation of intracellular signal transductionGO:19025312360.089
heart formationGO:006091460.089
striated muscle tissue developmentGO:0014706270.089
regulation of cell adhesionGO:0030155270.087
regulation of multicellular organism growthGO:0040014400.085
regulation of molecular functionGO:00650092170.084
muscle organ developmentGO:00075171270.080
negative regulation of cell developmentGO:0010721620.079
tissue deathGO:00162711020.079
regulation of protein metabolic processGO:00512462560.079
regulation of epithelial cell migration open tracheal systemGO:2000274110.079
negative regulation of response to stimulusGO:00485852580.078
gtp catabolic processGO:0006184720.077
anterior posterior pattern specification imaginal discGO:0007448160.076
courtship behaviorGO:0007619680.076
wnt signaling pathwayGO:0016055980.076
male courtship behaviorGO:0008049630.075
regulation of axon extension involved in axon guidanceGO:004884140.075
positive regulation of cellular protein metabolic processGO:00322701180.075
establishment of localization in cellGO:00516494020.075
positive regulation of phosphate metabolic processGO:00459371390.073
single organismal cell cell adhesionGO:0016337450.072
multi organism behaviorGO:00517051750.072
periodic partitioningGO:0007365290.071
intracellular signal transductionGO:00355563000.071
response to biotic stimulusGO:00096072940.070
kidney morphogenesisGO:006099330.070
regulation of epithelial cell differentiationGO:003085640.070
camera type eye developmentGO:004301040.069
positive regulation of developmental growthGO:0048639620.068
small molecule metabolic processGO:00442813050.068
neuroepithelial cell differentiationGO:006056360.067
neuroblast proliferationGO:0007405740.067
wound healingGO:0042060750.067
formation of organ boundaryGO:0010160300.066
regulation of response to external stimulusGO:00321011150.066
single organism biosynthetic processGO:00447112060.066
negative regulation of programmed cell deathGO:0043069720.066
establishment of planar polarityGO:0001736870.065
catabolic processGO:00090564090.065
regulation of cellular component biogenesisGO:00440872010.065
protein transportGO:00150311550.065
compound eye photoreceptor fate commitmentGO:0001752360.064
anterior posterior axis specification embryoGO:00085951030.063
extrinsic apoptotic signaling pathwayGO:009719110.063
negative regulation of cellular component organizationGO:00511291080.063
cell migration involved in gastrulationGO:004207490.063
regulation of cellular ketone metabolic processGO:001056530.061
positive regulation of neuron differentiationGO:0045666260.060
rhythmic processGO:00485111060.060
morphogenesis of a branching epitheliumGO:0061138450.060
photoreceptor cell differentiationGO:00465301700.060
regulation of neuron projection developmentGO:0010975690.059
establishment of protein localizationGO:00451841630.059
notch signaling pathwayGO:00072191200.058
protein modification processGO:00362114380.058
lipid metabolic processGO:00066291210.058
negative regulation of neurogenesisGO:0050768530.058
regulation of cell morphogenesis involved in differentiationGO:0010769610.058
positive regulation of multicellular organismal processGO:00512401430.056
camera type eye morphogenesisGO:004859320.056
immune responseGO:00069552460.056
hemopoiesisGO:0030097460.056
cell fate determinationGO:0001709910.055
positive regulation of cell migrationGO:003033520.055
positive regulation of signalingGO:00230562430.055
cell divisionGO:00513012480.055
response to woundingGO:0009611940.055
zygotic determination of anterior posterior axis embryoGO:0007354270.054
regulation of cellular component movementGO:0051270420.054
positive regulation of phosphorylationGO:0042327870.054
hindbrain developmentGO:003090220.053
regulation of mitotic cell cycleGO:00073461900.053
neurological system processGO:00508773580.053
epithelium migrationGO:00901321480.053
dna replicationGO:0006260480.053
determination of ventral identityGO:004826410.052
cognitionGO:00508901410.052
regulation of axon guidanceGO:1902667100.052
axis specificationGO:00097981670.051
regulation of bmp signaling pathwayGO:0030510230.051
positive regulation of nervous system developmentGO:0051962690.051
establishment or maintenance of cell polarityGO:00071631670.050
cellular protein modification processGO:00064644380.049
regulation of immune responseGO:00507761180.048
regulation of catalytic activityGO:00507901850.048
positive regulation of axonogenesisGO:005077220.048
vesicle mediated transportGO:00161923810.047
stem cell fate determinationGO:0048867150.046
lamellipodium organizationGO:0097581210.045
digestive tract mesoderm developmentGO:000750250.045
dorsal ventral axon guidanceGO:003356320.045
renal filtration cell differentiationGO:0061318120.045
ecdysone mediated induction of salivary gland cell autophagic cell deathGO:0035072120.045
photoreceptor cell axon guidanceGO:0072499230.044
positive regulation of signal transductionGO:00099672230.044
ectodermal placode morphogenesisGO:007169740.044
organic substance catabolic processGO:19015753080.044
establishment of tissue polarityGO:0007164870.043
defense responseGO:00069523000.043
genitalia developmentGO:0048806260.043
locomotory behaviorGO:00076261760.043
negative regulation of axon extensionGO:003051730.042
regulation of defense responseGO:00313471020.042
regulation of stem cell differentiationGO:2000736140.042
chemosensory behaviorGO:00076351060.042
segment polarity determinationGO:0007367250.042
response to sterolGO:0036314340.042
salivary gland histolysisGO:0035070880.042
nephron morphogenesisGO:007202830.042
determination of adult lifespanGO:00083401370.041
regulation of cellular amino acid metabolic processGO:000652100.041
agingGO:00075681430.041
carboxylic acid metabolic processGO:0019752920.041
protein complex biogenesisGO:00702712010.041
regulation of synapse assemblyGO:0051963940.041
organelle assemblyGO:00709251980.040
cell projection assemblyGO:0030031940.040
developmental inductionGO:003112830.040
mapk cascadeGO:00001651070.039
regulation of organ growthGO:0046620420.039
immune response activating signal transductionGO:000275720.039
neural precursor cell proliferationGO:0061351750.039
cellular catabolic processGO:00442483720.039
enzyme linked receptor protein signaling pathwayGO:00071671790.039
secretion by cellGO:00329401010.038
substrate dependent cell migrationGO:000692930.038
positive regulation of catabolic processGO:00098961050.038
regulation of steroid metabolic processGO:001921820.038
imaginal disc pattern formationGO:0007447910.038
nephron developmentGO:007200630.038
ovipositionGO:0018991190.037
protein catabolic processGO:00301631010.037
morphogenesis of a polarized epitheliumGO:0001738930.037
single organism catabolic processGO:00447122280.037
segment specificationGO:0007379330.037
immune response regulating signaling pathwayGO:000276420.036
chromatin organizationGO:00063252070.036
mesenchymal cell differentiationGO:004876210.036
olfactory behaviorGO:0042048970.036
muscle cell developmentGO:0055001500.036
cellular amino acid metabolic processGO:0006520610.036
cell growthGO:00160491080.036
nucleoside phosphate catabolic processGO:19012921100.035
neuromuscular junction developmentGO:00075281490.035
gastrulation involving germ band extensionGO:0010004360.035
embryonic axis specificationGO:00005781070.035
regulation of cell shapeGO:00083601130.034
embryonic organ developmentGO:0048568500.034
positive regulation of phosphorus metabolic processGO:00105621390.034
cell surface receptor signaling pathway involved in heart developmentGO:006131130.034
endocytosisGO:00068973100.034
cell recognitionGO:00080371020.033
cellular macromolecule localizationGO:00707272200.033
axon extensionGO:0048675320.032
hair cell differentiationGO:0035315470.032
nucleoside metabolic processGO:00091161270.032
signal transduction by phosphorylationGO:00230141070.032
cell junction organizationGO:0034330570.032
positive regulation of organelle organizationGO:0010638650.032
response to organic substanceGO:00100332840.032
post embryonic appendage morphogenesisGO:00351203850.032
head involutionGO:0008258350.032
purine nucleoside triphosphate catabolic processGO:00091461080.031
regulation of oocyte developmentGO:0060281270.031
positive regulation of cell deathGO:0010942690.031
response to endogenous stimulusGO:00097191190.031
regulation of dendrite morphogenesisGO:0048814280.031
pole plasm assemblyGO:0007315610.031
amine metabolic processGO:0009308120.030
central nervous system projection neuron axonogenesisGO:002195260.030
outflow tract morphogenesisGO:000315140.030
organonitrogen compound metabolic processGO:19015643180.030
regulation of cell projection organizationGO:0031344920.030
connective tissue developmentGO:006144830.030
canonical wnt signaling pathwayGO:0060070210.030
mesenchymal cell developmentGO:001403110.030
response to bacteriumGO:00096171980.030
determination of bilateral symmetryGO:0009855130.029
male mating behaviorGO:0060179700.029
negative regulation of stem cell differentiationGO:200073780.029
nucleobase containing compound catabolic processGO:00346551650.029
olfactory learningGO:0008355560.029
organic acid metabolic processGO:00060821030.029
regulation of localizationGO:00328792750.029
steroid biosynthetic processGO:0006694160.028
regulation of phosphate metabolic processGO:00192202100.028
negative regulation of cell cycle processGO:00109481090.028
purine nucleoside catabolic processGO:00061521120.028
branching morphogenesis of an epithelial tubeGO:0048754450.028
nephron epithelium morphogenesisGO:007208830.028
positive regulation of protein metabolic processGO:00512471280.028
leg disc developmentGO:0035218920.028
regulation of catabolic processGO:00098941700.027
purine ribonucleotide catabolic processGO:00091541090.027
autophagic cell deathGO:0048102830.027
cellular response to organic substanceGO:00713101320.026
regulation of lipid metabolic processGO:0019216150.026
sensory organ precursor cell fate determinationGO:0016360190.026
positive regulation of cellular amino acid metabolic processGO:004576400.026
positive regulation of molecular functionGO:00440931360.026
induction of programmed cell deathGO:0012502120.026
lymph gland developmentGO:0048542280.026
regulation of cell fate specificationGO:0042659270.026
negative regulation of cell proliferationGO:0008285690.026
positive regulation of cellular amine metabolic processGO:003324000.025
defense response to other organismGO:00985422250.025
muscle fiber developmentGO:0048747120.025
purine ribonucleoside triphosphate metabolic processGO:00092051190.025
regulation of cell cycleGO:00517262910.025
positive regulation of cell differentiationGO:0045597640.025
regulation of phosphorus metabolic processGO:00511742100.025
pigmentationGO:0043473750.025
memoryGO:0007613940.025
glandular epithelial cell differentiationGO:000206710.025
midgut developmentGO:0007494230.024
regulation of wnt signaling pathwayGO:0030111680.024
limb morphogenesisGO:003510810.024
cellular response to monosaccharide stimulusGO:007132620.024
regulation of stem cell proliferationGO:0072091400.024
regulation of transferase activityGO:0051338580.024
regulation of lamellipodium assemblyGO:0010591150.024
hemocyte differentiationGO:0042386380.024
purine nucleoside metabolic processGO:00422781270.023
lamellipodium assemblyGO:0030032210.023
carbohydrate derivative metabolic processGO:19011352170.023
defense response to bacteriumGO:00427421780.023
muscle cell differentiationGO:00426921030.023
regulation of transportGO:00510491810.023
positive regulation of immune system processGO:0002684680.023
ribonucleotide catabolic processGO:00092611090.023
ribonucleoside triphosphate metabolic processGO:00091991190.023
developmental pigmentationGO:0048066680.023
regulation of cellular component sizeGO:0032535980.023
regulation of cellular catabolic processGO:00313291570.023
positive regulation of cellular catabolic processGO:0031331950.022
organelle localizationGO:00516401480.022
cuticle developmentGO:0042335860.022
terminal region determinationGO:0007362250.022
negative regulation of mitotic cell cycleGO:00459301090.022
spindle organizationGO:00070512530.022
mitotic nuclear divisionGO:00070672130.022
oxoacid metabolic processGO:00434361030.021
stem cell maintenanceGO:0019827670.021
regulation of protein modification processGO:00313991120.021
phosphorylationGO:00163102940.021
macromolecular complex assemblyGO:00650032560.021
immune effector processGO:0002252980.021
regulation of canonical wnt signaling pathwayGO:0060828150.021
ribonucleoside triphosphate catabolic processGO:00092031080.021
regulation of innate immune responseGO:0045088710.021
positive regulation of lipid metabolic processGO:004583440.021
organic substance transportGO:00717022570.021
wing disc morphogenesisGO:00074723440.021
regulation of hemocyte differentiationGO:0045610220.021
positive regulation of intracellular signal transductionGO:19025331160.021
regulation of hydrolase activityGO:0051336970.021
response to organic cyclic compoundGO:0014070890.021

hkb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.078
disease of anatomical entityDOID:700.078
waardenburg s syndromeDOID:925800.032