IMP: Integrative Multi-species Prediction

Drosophila melanogaster

21 known processes

eIF3-S10 (Dmel_CG9805)

CG9805 gene product from transcript CG9805-RA

(Aliases: Dmel\CG9805,CG9805,MMAP140,anon-WO0118547.261)

FLYBASE: FBgn0037249
Entrez: 40563
UniProtKB: Q9VN25

Process Predictions
Disease Predictions

eIF3-S10 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
mitotic spindle elongation	GO:0000022	81	0.317
body morphogenesis	GO:0010171	2	0.282	Worm
spindle elongation	GO:0051231	83	0.251
rna processing	GO:0006396	147	0.243
translational initiation	GO:0006413	11	0.188	Human Yeast Mouse
regulation of cell cycle process	GO:0010564	181	0.170
programmed cell death	GO:0012501	257	0.156
cellular macromolecule localization	GO:0070727	220	0.156
mrna processing	GO:0006397	104	0.155
establishment of localization in cell	GO:0051649	402	0.148
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.142
regulation of apoptotic process	GO:0042981	130	0.135
response to external biotic stimulus	GO:0043207	293	0.133
nuclear division	GO:0000280	332	0.131
single organism intracellular transport	GO:1902582	207	0.127
translation	GO:0006412	69	0.125	Human Yeast Mouse
gene silencing by rna	GO:0031047	57	0.123
death	GO:0016265	284	0.115
cytoplasmic transport	GO:0016482	130	0.108
posttranscriptional regulation of gene expression	GO:0010608	145	0.108
cell death	GO:0008219	279	0.107
cell division	GO:0051301	248	0.105
organelle fission	GO:0048285	340	0.099
mitotic nuclear division	GO:0007067	213	0.097
endocytosis	GO:0006897	310	0.097	Worm
mitotic spindle organization	GO:0007052	220	0.095
negative regulation of gene expression	GO:0010629	387	0.091
negative regulation of biosynthetic process	GO:0009890	277	0.088
regulation of translation	GO:0006417	56	0.087
meiotic cell cycle	GO:0051321	171	0.084
rna interference	GO:0016246	27	0.075
spindle organization	GO:0007051	253	0.074
tube development	GO:0035295	244	0.072
protein transport	GO:0015031	155	0.072
regulation of meiosis	GO:0040020	3	0.070
negative regulation of cell cycle process	GO:0010948	109	0.070
larval development	GO:0002164	104	0.068	Worm
negative regulation of cell cycle phase transition	GO:1901988	103	0.068
immune system process	GO:0002376	347	0.067
positive regulation of transcription dna templated	GO:0045893	266	0.062
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.060
cellular response to chemical stimulus	GO:0070887	199	0.060
single organism cellular localization	GO:1902580	180	0.055
negative regulation of mitotic cell cycle	GO:0045930	109	0.054
mrna metabolic process	GO:0016071	124	0.052
nuclear transport	GO:0051169	72	0.050
regulation of protein metabolic process	GO:0051246	256	0.050
defense response	GO:0006952	300	0.049
intracellular transport	GO:0046907	228	0.047
cellular catabolic process	GO:0044248	372	0.046
negative regulation of cellular biosynthetic process	GO:0031327	277	0.046
apoptotic process	GO:0006915	159	0.045
multicellular organismal aging	GO:0010259	140	0.045	Worm
lipid storage	GO:0019915	38	0.045
response to biotic stimulus	GO:0009607	294	0.043
oocyte differentiation	GO:0009994	145	0.043
regulation of response to stress	GO:0080134	200	0.042
vesicle mediated transport	GO:0016192	381	0.042	Worm
regulation of cell cycle	GO:0051726	291	0.042
protein modification process	GO:0036211	438	0.042
digestive system development	GO:0055123	149	0.039
cellular response to organic substance	GO:0071310	132	0.037
embryo development ending in birth or egg hatching	GO:0009792	152	0.037	Worm
hematopoietic or lymphoid organ development	GO:0048534	57	0.036
mesenchymal cell differentiation	GO:0048762	1	0.035
organic substance transport	GO:0071702	257	0.035
cellular protein localization	GO:0034613	160	0.034
brain development	GO:0007420	120	0.033
g2 dna damage checkpoint	GO:0031572	69	0.032
stem cell development	GO:0048864	79	0.032
regulation of cellular localization	GO:0060341	136	0.031
nuclear export	GO:0051168	24	0.030
cellular protein modification process	GO:0006464	438	0.030
nucleocytoplasmic transport	GO:0006913	72	0.030
hematopoietic stem cell differentiation	GO:0060218	1	0.030
nuclear pore organization	GO:0006999	1	0.030
regulation of immune system process	GO:0002682	176	0.029
determination of adult lifespan	GO:0008340	137	0.029	Worm
axis specification	GO:0009798	167	0.028
posttranscriptional gene silencing by rna	GO:0035194	45	0.028
sex differentiation	GO:0007548	81	0.027
regulation of programmed cell death	GO:0043067	152	0.027
regulation of gene expression epigenetic	GO:0040029	128	0.026
rrna processing	GO:0006364	3	0.026
regulation of cell cycle phase transition	GO:1901987	130	0.025
rna splicing via transesterification reactions	GO:0000375	73	0.025
positive regulation of immune system process	GO:0002684	68	0.025
retina development in camera type eye	GO:0060041	4	0.025
regulation of nucleobase containing compound transport	GO:0032239	4	0.025
protein maturation	GO:0051604	71	0.024
regulation of cellular protein metabolic process	GO:0032268	243	0.024
aging	GO:0007568	143	0.024	Worm
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.023
regulation of hydrolase activity	GO:0051336	97	0.023
mesenchymal cell development	GO:0014031	1	0.022
chromatin modification	GO:0016568	147	0.022
intracellular protein transport	GO:0006886	104	0.022
positive regulation of cellular biosynthetic process	GO:0031328	316	0.022
regulation of cell differentiation	GO:0045595	302	0.021
positive regulation of gene expression	GO:0010628	290	0.021
cellular macromolecular complex assembly	GO:0034622	153	0.021	Human Mouse
negative regulation of rna biosynthetic process	GO:1902679	240	0.021
cell proliferation	GO:0008283	299	0.020
regulation of mrna metabolic process	GO:1903311	72	0.020
cellular nitrogen compound catabolic process	GO:0044270	165	0.020
carbohydrate derivative metabolic process	GO:1901135	217	0.020
protein destabilization	GO:0031648	2	0.020
mitotic cell cycle phase transition	GO:0044772	138	0.019
locomotory behavior	GO:0007626	176	0.019
rna localization	GO:0006403	115	0.019
protein localization	GO:0008104	284	0.019
response to abiotic stimulus	GO:0009628	341	0.019
cell cycle phase transition	GO:0044770	140	0.018
regulation of cell death	GO:0010941	173	0.018
mrna transport	GO:0051028	15	0.018
negative regulation of rna metabolic process	GO:0051253	251	0.018
establishment of protein localization	GO:0045184	163	0.018
negative regulation of cell cycle	GO:0045786	116	0.018
ribonucleoprotein complex biogenesis	GO:0022613	31	0.018	Human Mouse
cytoplasmic translation	GO:0002181	0	0.018	Human Yeast Mouse
regulation of mrna processing	GO:0050684	71	0.017
multi organism behavior	GO:0051705	175	0.017	Worm
organonitrogen compound metabolic process	GO:1901564	318	0.017
regulation of dna metabolic process	GO:0051052	34	0.017
single organism biosynthetic process	GO:0044711	206	0.017
response to other organism	GO:0051707	293	0.017
negative regulation of multicellular organismal process	GO:0051241	142	0.017
regulation of nuclear division	GO:0051783	58	0.017
positive regulation of macromolecule metabolic process	GO:0010604	405	0.017
regulation of transport	GO:0051049	181	0.016
lipid localization	GO:0010876	54	0.016
head development	GO:0060322	135	0.016
hemopoiesis	GO:0030097	46	0.016
cellular component disassembly	GO:0022411	46	0.015
phagocytosis	GO:0006909	215	0.015
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.015
cellular response to decreased oxygen levels	GO:0036294	30	0.015
appendage development	GO:0048736	401	0.015
nucleoside phosphate metabolic process	GO:0006753	162	0.015
maintenance of location	GO:0051235	73	0.015
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.015
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.015
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.014
protein targeting	GO:0006605	64	0.014
purine nucleotide metabolic process	GO:0006163	146	0.014
meiotic nuclear division	GO:0007126	151	0.014
rna catabolic process	GO:0006401	37	0.014
heterocycle catabolic process	GO:0046700	166	0.014
anterior posterior pattern specification	GO:0009952	136	0.014
histone methylation	GO:0016571	40	0.014
lipid metabolic process	GO:0006629	121	0.013
nucleobase containing compound catabolic process	GO:0034655	165	0.013
growth	GO:0040007	359	0.013
negative regulation of cellular metabolic process	GO:0031324	382	0.013
small molecule metabolic process	GO:0044281	305	0.013
organic cyclic compound catabolic process	GO:1901361	168	0.013
ribonucleoprotein complex assembly	GO:0022618	23	0.013	Human Mouse
stem cell differentiation	GO:0048863	117	0.013
gonad development	GO:0008406	50	0.013
nuclear transcribed mrna catabolic process nonsense mediated decay	GO:0000184	8	0.013
cellular response to oxygen levels	GO:0071453	30	0.013
macromolecular complex assembly	GO:0065003	256	0.013	Human Mouse
negative regulation of protein metabolic process	GO:0051248	85	0.013
ncrna metabolic process	GO:0034660	43	0.012
regulation of chromatin modification	GO:1903308	28	0.012
tissue morphogenesis	GO:0048729	297	0.012
dorsal ventral axis specification	GO:0009950	66	0.012
proteolysis	GO:0006508	192	0.012
tripartite regional subdivision	GO:0007351	103	0.012
regionalization	GO:0003002	416	0.012
post embryonic appendage morphogenesis	GO:0035120	385	0.012
oocyte development	GO:0048599	124	0.012
regulation of mitotic cell cycle	GO:0007346	190	0.012
oocyte axis specification	GO:0007309	108	0.012
axon development	GO:0061564	297	0.012
spliceosomal snrnp assembly	GO:0000387	2	0.012
transcription from rna polymerase ii promoter	GO:0006366	368	0.012
macromolecule catabolic process	GO:0009057	161	0.011
posttranscriptional gene silencing	GO:0016441	46	0.011
chromatin organization	GO:0006325	207	0.011
peptidyl lysine trimethylation	GO:0018023	6	0.011
compound eye development	GO:0048749	307	0.011
actin cytoskeleton organization	GO:0030036	206	0.011
organophosphate metabolic process	GO:0019637	195	0.011
rhythmic process	GO:0048511	106	0.011
cardiovascular system development	GO:0072358	82	0.011
histone lysine methylation	GO:0034968	32	0.011
pole plasm mrna localization	GO:0019094	49	0.011
response to organic substance	GO:0010033	284	0.011
cellular protein complex disassembly	GO:0043624	35	0.011
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.010
catabolic process	GO:0009056	409	0.010
dendrite development	GO:0016358	204	0.010
fatty acid derivative biosynthetic process	GO:1901570	1	0.010
nucleotide metabolic process	GO:0009117	161	0.010
spliceosomal complex assembly	GO:0000245	1	0.010
negative regulation of cell differentiation	GO:0045596	143	0.010
gland development	GO:0048732	191	0.010

eIF3-S10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.019
	syndrome	DOID:225	0	0.010

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