Homo sapiens

0 known processes

SMEK1

SMEK homolog 1, suppressor of mek1 (Dictyostelium)

(Aliases: smk1,PP4R3A,FLFL1,smk-1,KIAA2010)

SMEK1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
double strand break repair via homologous recombinationGO:0000724500.731
cellular response to dna damage stimulusGO:00069743790.714
regulation of double strand break repair via homologous recombinationGO:0010569110.702
recombinational repairGO:0000725500.670
regulation of dna repairGO:0006282470.606
regulation of response to dna damage stimulusGO:2001020940.596
regulation of dna metabolic processGO:00510521530.553
dna repairGO:00062811980.543
double strand break repairGO:00063021010.460
regulation of cellular response to stressGO:00801352440.439
regulation of double strand break repairGO:2000779220.428
regulation of dna recombinationGO:0000018230.382
carbohydrate metabolic processGO:00059752070.289
Mouse
protein glycosylationGO:0006486620.206
cardiovascular system developmentGO:00723582620.192
peptidyl serine phosphorylationGO:00181051010.113
cell cycle checkpointGO:00000751170.110
positive regulation of dna metabolic processGO:0051054730.094
chromatin modificationGO:00165682980.094
peptidyl lysine acetylationGO:00183941010.090
dna recombinationGO:0006310770.080
female gamete generationGO:000729220.079
cellular amine metabolic processGO:0044106410.077
protein modification by small protein conjugationGO:00324463420.075
microtubule based processGO:00070172100.073
anatomical structure formation involved in morphogenesisGO:00486462840.073
response to cytokineGO:00340972320.070
ras protein signal transductionGO:0007265730.069
peptidyl lysine modificationGO:00182051440.064
negative regulation of cell deathGO:00605483450.063
oxidation reduction processGO:00551143960.063
post embryonic developmentGO:000979120.061
regulation of cellular amino acid metabolic processGO:000652160.060
negative regulation of proteolysisGO:00458611320.060
regulation of meiotic cell cycleGO:005144540.059
histone modificationGO:00165702510.059
neural tube formationGO:000184130.059
peptidyl serine modificationGO:00182091060.057
central nervous system neuron axonogenesisGO:002195530.056
protein autophosphorylationGO:00467771230.055
posttranscriptional regulation of gene expressionGO:00106082130.054
cellular ketone metabolic processGO:0042180800.054
Mouse
positive regulation of programmed cell deathGO:00430682490.053
protein acetylationGO:00064731160.053
positive regulation of response to dna damage stimulusGO:2001022430.053
internal protein amino acid acetylationGO:00064751010.052
regulation of cellular amine metabolic processGO:0033238110.050
dna integrity checkpointGO:0031570710.050
regulation of cellular ketone metabolic processGO:0010565500.050
Mouse
microtubule cytoskeleton organizationGO:00002261760.048
oogenesisGO:004847720.047
embryonic viscerocranium morphogenesisGO:004870310.044
amine metabolic processGO:0009308440.044
internal peptidyl lysine acetylationGO:0018393970.043
positive regulation of apoptotic processGO:00430652460.041
regulation of meiosisGO:004002030.040
negative regulation of phosphorus metabolic processGO:00105632670.040
cellular amino acid metabolic processGO:00065201160.039
cellular response to interleukin 1GO:0071347350.038
cellular glucan metabolic processGO:0006073220.038
negative regulation of protein metabolic processGO:00512483910.038
protein processingGO:00164852260.037
response to oxygen containing compoundGO:19017003690.037
regulation of mapk cascadeGO:00434082620.037
nervous system developmentGO:00073992930.036
glycosylationGO:0070085710.036
negative regulation of catalytic activityGO:00430863350.036
macromolecule glycosylationGO:0043413630.036
signal transduction by phosphorylationGO:00230142970.035
neuroblast proliferationGO:000740540.034
negative regulation of protein processingGO:00109551420.032
regulation of stress activated mapk cascadeGO:0032872840.032
endomembrane system organizationGO:00102561960.032
cellular component morphogenesisGO:00329893140.031
immune responseGO:00069553070.031
regulation of proteolysisGO:00301622930.031
stress activated mapk cascadeGO:0051403930.030
rna interferenceGO:001624640.030
regulation of protein complex assemblyGO:00432541470.029
heart developmentGO:0007507950.029
defense responseGO:00069523150.029
covalent chromatin modificationGO:00165692540.029
regulation of homeostatic processGO:00328441210.029
determination of adult lifespanGO:000834020.029
histone acetylationGO:0016573930.029
cellular response to arsenic containing substanceGO:007124340.029
chromatin organizationGO:00063253510.028
carbohydrate derivative biosynthetic processGO:19011372070.028
rho protein signal transductionGO:0007266260.028
protein acylationGO:00435431380.027
negative regulation of catabolic processGO:00098951040.027
glycoprotein metabolic processGO:00091001100.027
head developmentGO:00603221080.027
hemopoiesisGO:00300971800.027
anterior posterior axis specificationGO:000994820.027
cell developmentGO:00484683280.027
positive regulation of phosphorylationGO:00423273940.027
morphogenesis of embryonic epitheliumGO:001633140.027
negative regulation of apoptotic processGO:00430663160.026
positive regulation of immune system processGO:00026842830.026
protein stabilizationGO:0050821640.026
negative regulation of cellular protein metabolic processGO:00322693530.026
glycoprotein biosynthetic processGO:0009101910.026
negative regulation of cellular amino acid metabolic processGO:004576320.026
negative regulation of protein maturationGO:19033181420.026
circulatory system developmentGO:00723592620.026
behavioral response to ethanolGO:004814920.025
regulation of kinase activityGO:00435493140.025
cellular polysaccharide metabolic processGO:0044264270.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
mapk cascadeGO:00001652880.025
blood vessel morphogenesisGO:00485141620.025
embryonic epithelial tube formationGO:000183840.025
reproductive processGO:00224141060.024
behaviorGO:00076101120.024
regulation of cell cycleGO:00517263930.024
response to carbohydrateGO:0009743210.024
positive regulation of cellular amine metabolic processGO:003324070.024
erk1 and erk2 cascadeGO:00703711040.023
regulation of cell cycle processGO:00105642660.023
response to salt stressGO:000965130.023
regulation of translationGO:0006417890.023
cell morphogenesisGO:00009022960.022
glucose homeostasisGO:0042593310.022
stress activated protein kinase signaling cascadeGO:0031098940.022
negative regulation of cell cycleGO:00457861930.022
positive regulation of mapk cascadeGO:00434101900.022
oocyte developmentGO:004859910.022
protein deubiquitinationGO:0016579790.022
regulation of protein processingGO:00706131500.022
hematopoietic or lymphoid organ developmentGO:00485341860.022
multicellular organismal agingGO:001025930.021
cellular chemical homeostasisGO:00550821800.021
positive regulation of cellular component organizationGO:00511303760.021
positive regulation of transferase activityGO:00513472270.021
spermatid differentiationGO:004851540.021
dna dependent dna replicationGO:0006261440.021
regulation of chromosome organizationGO:00330441030.021
regulation of response to external stimulusGO:00321012220.020
vasculature developmentGO:00019441810.020
canonical wnt signaling pathwayGO:00600701160.020
response to abiotic stimulusGO:00096283360.020
regulation of transferase activityGO:00513383550.020
proteolysis involved in cellular protein catabolic processGO:00516032440.020
response to tumor necrosis factorGO:0034612760.020
segmentationGO:003528240.020
meiotic chromosome segregationGO:004513240.020
regulation of protein maturationGO:19033171500.020
negative regulation of intracellular signal transductionGO:19025321830.020
positive regulation of protein phosphorylationGO:00019343130.020
locomotory behaviorGO:000762610.019
dna replicationGO:00062601160.019
immune system developmentGO:00025201950.019
negative regulation of hydrolase activityGO:00513461820.019
regulation of small gtpase mediated signal transductionGO:00510561560.019
regulation of stress activated protein kinase signaling cascadeGO:0070302850.019
positive regulation of cell deathGO:00109422630.019
positive regulation of dna replicationGO:0045740350.019
negative regulation of cellular amine metabolic processGO:003323930.019
response to biotic stimulusGO:00096072760.019
regulation of peptidase activityGO:00525471800.018
innate immune responseGO:00450871780.018
cellular response to oxygen containing compoundGO:19017012760.018
regulation of protein kinase activityGO:00458592890.018
cellular carbohydrate metabolic processGO:0044262840.018
Mouse
cartilage condensationGO:000150210.018
myeloid cell differentiationGO:00300991170.018
translationGO:00064121320.018
protein ubiquitinationGO:00165673140.018
positive regulation of immune responseGO:00507781590.018
nuclear transportGO:00511691790.017
regulation of immune responseGO:00507762010.017
glycogen metabolic processGO:0005977220.017
positive regulation of transportGO:00510503360.017
activation of protein kinase activityGO:0032147900.017
chemical homeostasisGO:00488783060.017
blood vessel developmentGO:00015681720.017
regulation of anatomical structure sizeGO:00900661010.017
organ morphogenesisGO:00098871470.017
extrinsic apoptotic signaling pathwayGO:00971911190.017
brain developmentGO:0007420970.017
negative regulation of programmed cell deathGO:00430693210.017
response to fungusGO:000962040.017
mrna metabolic processGO:00160711750.017
cellular protein catabolic processGO:00442572610.017
embryo developmentGO:00097901230.017
regulation of mrna metabolic processGO:1903311530.017
regulation of histone acetylationGO:0035065190.016
negative regulation of protein modification processGO:00314002000.016
regulation of canonical wnt signaling pathwayGO:0060828880.016
regulation of cytokine productionGO:00018172320.016
generation of precursor metabolites and energyGO:0006091680.016
protein oligomerizationGO:00512591730.016
purine ribonucleoside triphosphate metabolic processGO:00092054110.016
central nervous system developmentGO:00074171230.016
single organism carbohydrate metabolic processGO:00447231930.016
Mouse
spermatid developmentGO:000728640.016
positive regulation of organelle organizationGO:00106381950.016
negative regulation of endopeptidase activityGO:0010951840.016
blastoderm segmentationGO:000735020.016
apoptotic signaling pathwayGO:00971902680.016
i kappab kinase nf kappab signalingGO:00072491660.015
protein dephosphorylationGO:0006470810.015
Mouse
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.015
forelimb morphogenesisGO:003513640.015
secretionGO:00469032540.015
protein modification by small protein removalGO:0070646920.015
protein maturationGO:00516042330.015
cellular homeostasisGO:00197251960.015
negative regulation of organelle organizationGO:00106391260.015
regulation of apoptotic signaling pathwayGO:20012331750.015
morphogenesis of an epitheliumGO:0002009600.015
cellular response to cytokine stimulusGO:00713451810.015
epithelium developmentGO:00604292270.014
regulation of response to woundingGO:19030341010.014
embryonic placenta developmentGO:000189210.014
purine ribonucleoside catabolic processGO:00461303980.014
negative regulation of cellular component organizationGO:00511292350.014
memoryGO:000761330.014
protein catabolic processGO:00301633250.014
ribonucleoside catabolic processGO:00424544060.014
regulation of cysteine type endopeptidase activityGO:20001161270.014
positive regulation of cellular component biogenesisGO:00440891580.014
positive regulation of cell cycle processGO:00900681060.014
maintenance of locationGO:00512351120.014
positive regulation of cell sizeGO:004579330.014
regulation of erk1 and erk2 cascadeGO:0070372990.014
cell activationGO:00017752130.013
regulation of jnk cascadeGO:0046328730.013
regulation of cytoskeleton organizationGO:00514931770.013
neural tube closureGO:000184330.013
regulation of microtubule based processGO:0032886740.013
dosage compensationGO:000754930.013
cell projection organizationGO:00300302520.013
cellular protein complex assemblyGO:00436231880.013
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.013
regulation of cell morphogenesisGO:00226041530.013
glycerolipid metabolic processGO:00464861070.013
ribonucleotide catabolic processGO:00092614050.013
small gtpase mediated signal transductionGO:0007264780.013
protein homooligomerizationGO:00512601000.013
negative regulation of oxidative stress induced cell deathGO:1903202170.013
regulation of ras protein signal transductionGO:00465781550.013
system processGO:00030083490.012
histone lysine methylationGO:0034968500.012
negative regulation of cysteine type endopeptidase activityGO:2000117480.012
dna conformation changeGO:00711031130.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.012
lipid localizationGO:00108761060.012
neurotransmitter secretionGO:000726940.012
anatomical structure homeostasisGO:00602491000.012
energy derivation by oxidation of organic compoundsGO:0015980430.012
regulation of chromatin modificationGO:1903308510.012
regulation of cellular component biogenesisGO:00440872810.012
negative regulation of cellular catabolic processGO:0031330830.012
macromolecule methylationGO:0043414970.012
negative regulation of cell cycle phase transitionGO:1901988890.012
regulation of growthGO:00400081650.012
neuron projection developmentGO:00311751060.012
neuron developmentGO:00486661130.012
regulation of endopeptidase activityGO:00525481700.012
neurological system processGO:00508771630.012
angiogenesisGO:00015251470.012
regulation of vesicle mediated transportGO:00606271300.012
cellular response to external stimulusGO:00714961110.012
nucleotide catabolic processGO:00091664080.012
negative regulation of cell cycle processGO:00109481210.012
defense response to bacteriumGO:0042742630.012
negative regulation of chromatin silencingGO:003193640.012
rna processingGO:00063962550.011
regulation of peptidyl lysine acetylationGO:2000756220.011
regulation of rho gtpase activityGO:0032319660.011
protein heterotrimerizationGO:007020840.011
negative regulation of bindingGO:0051100570.011
jnk cascadeGO:0007254800.011
regulation of map kinase activityGO:00434051080.011
cytokine productionGO:00018162470.011
positive regulation of protein kinase activityGO:00458601900.011
skeletal system developmentGO:0001501790.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
reproductive system developmentGO:0061458560.011
heart morphogenesisGO:0003007480.011
neurogenesisGO:00220081690.011
modification dependent protein catabolic processGO:00199412090.011
negative regulation of phosphatase activityGO:0010923610.011
response to external biotic stimulusGO:00432072610.011
regulation of dna replicationGO:0006275680.011
regulation of proteasomal protein catabolic processGO:0061136870.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.011
reactive oxygen species biosynthetic processGO:190340940.011
peptidyl threonine phosphorylationGO:0018107410.011
regulation of myeloid cell differentiationGO:0045637810.011
adult locomotory behaviorGO:000834410.011
regulation of gene expression epigeneticGO:0040029730.011
negative regulation of response to external stimulusGO:0032102830.010
cellular macromolecule catabolic processGO:00442653800.010
cell growthGO:00160491600.010
central nervous system neuron developmentGO:002195470.010
tor signalingGO:0031929390.010
defense response to fungusGO:005083240.010
regulation of intracellular transportGO:00323861950.010
cell part morphogenesisGO:00329901370.010
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.010
negative regulation of mapk cascadeGO:0043409560.010
activation of mapk activityGO:0000187450.010
positive regulation of hydrolase activityGO:00513453310.010
gene silencingGO:0016458490.010
negative regulation of cell differentiationGO:00455961710.010

SMEK1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.042
eye and adnexa diseaseDOID:14921500.042
sensory system diseaseDOID:00501552030.042
eye diseaseDOID:56141490.039