Homo sapiens

47 known processes

PDK2

pyruvate dehydrogenase kinase, isozyme 2

(Aliases: PDHK2)

PDK2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.300
cellular ketone metabolic processGO:0042180800.124
Human
regulation of cellular amino acid metabolic processGO:000652160.112
regulation of cellular ketone metabolic processGO:0010565500.111
Human
regulation of cellular amine metabolic processGO:0033238110.103
amine metabolic processGO:0009308440.100
cellular lipid metabolic processGO:00442553030.080
Human
cellular amine metabolic processGO:0044106410.077
positive regulation of cellular amine metabolic processGO:003324070.075
post embryonic developmentGO:000979120.074
lipid metabolic processGO:00066293810.064
Human
positive regulation of cellular amino acid metabolic processGO:004576430.059
organonitrogen compound biosynthetic processGO:19015662000.056
regulation of cellular component biogenesisGO:00440872810.055
posttranscriptional regulation of gene expressionGO:00106082130.054
cation transportGO:00068123310.051
regulation of cell cycleGO:00517263930.045
nervous system developmentGO:00073992930.045
cellular homeostasisGO:00197251960.042
negative regulation of cellular protein metabolic processGO:00322693530.041
small molecule biosynthetic processGO:00442831570.041
Human
oogenesisGO:004847720.039
determination of adult lifespanGO:000834020.038
positive regulation of transportGO:00510503360.038
cation homeostasisGO:00550801890.037
protein ubiquitinationGO:00165673140.036
oxidation reduction processGO:00551143960.036
negative regulation of protein metabolic processGO:00512483910.035
multicellular organismal agingGO:001025930.035
chromatin organizationGO:00063253510.034
negative regulation of phosphate metabolic processGO:00459362670.034
mitotic cell cycle processGO:19030472860.034
neuromuscular junction developmentGO:000752830.034
positive regulation of ion transportGO:0043270870.033
response to abiotic stimulusGO:00096283360.033
Human
regulation of ion transportGO:00432691890.032
organelle fissionGO:00482851490.032
single organism cellular localizationGO:19025803320.032
negative regulation of cellular amine metabolic processGO:003323930.031
ribonucleoside triphosphate catabolic processGO:00092033910.031
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.031
purine nucleoside triphosphate metabolic processGO:00091444120.031
chemical homeostasisGO:00488783060.030
protein modification by small protein conjugationGO:00324463420.030
positive regulation of phosphorylationGO:00423273940.030
positive regulation of synaptic transmissionGO:005080640.029
protein catabolic processGO:00301633250.029
regulation of cell cycle processGO:00105642660.029
apoptotic signaling pathwayGO:00971902680.028
purine ribonucleoside metabolic processGO:00461284370.028
organophosphate biosynthetic processGO:00904071630.028
system processGO:00030083490.028
negative regulation of catalytic activityGO:00430863350.028
regulation of transferase activityGO:00513383550.028
response to organic cyclic compoundGO:00140702040.027
cytoplasmic transportGO:00164823790.027
membrane organizationGO:00610242920.027
regulation of proteolysisGO:00301622930.027
negative regulation of phosphorus metabolic processGO:00105632670.027
covalent chromatin modificationGO:00165692540.027
mitotic cell cycleGO:00002783260.026
regulation of protein complex assemblyGO:00432541470.026
positive regulation of cellular component organizationGO:00511303760.026
purine containing compound catabolic processGO:00725234110.026
response to oxygen containing compoundGO:19017003690.025
metal ion homeostasisGO:00550651690.025
carboxylic acid biosynthetic processGO:0046394970.025
Human
nucleoside triphosphate metabolic processGO:00091414220.025
positive regulation of protein phosphorylationGO:00019343130.025
nucleoside phosphate catabolic processGO:19012924120.024
positive regulation of developmental processGO:00510943140.024
regulation of intracellular transportGO:00323861950.024
vesicle mediated transportGO:00161923710.024
compound eye developmentGO:004874910.024
cellular response to nitrogen compoundGO:19016991440.024
Human
lipid biosynthetic processGO:00086101770.024
Human
peptidyl serine phosphorylationGO:00181051010.024
Human Rat
cellular response to endogenous stimulusGO:00714953360.024
Human
calcium ion homeostasisGO:00550741220.024
memoryGO:000761330.024
negative regulation of phosphorylationGO:00423261740.023
monocarboxylic acid metabolic processGO:00327871850.023
Human
cellular chemical homeostasisGO:00550821800.023
regulation of protein localizationGO:00328802960.023
nucleotide catabolic processGO:00091664080.023
single organism membrane organizationGO:00448022680.023
cellular response to oxygen containing compoundGO:19017012760.023
dephosphorylationGO:00163112090.023
positive regulation of organelle organizationGO:00106381950.022
neurotransmitter secretionGO:000726940.022
carboxylic acid catabolic processGO:0046395710.022
fatty acid metabolic processGO:00066311150.022
Human
sequestering of calcium ionGO:0051208170.022
negative regulation of developmental processGO:00510932470.022
regulation of nucleotide metabolic processGO:00061402690.022
reactive oxygen species metabolic processGO:0072593750.022
Human
regulation of lipid metabolic processGO:0019216960.022
Human
secretion by cellGO:00329402260.022
response to nitrogen compoundGO:19016981840.022
Human
regulation of dephosphorylationGO:0035303960.021
regulation of neurotransmitter secretionGO:004692830.021
ribonucleoside catabolic processGO:00424544060.021
ras protein signal transductionGO:0007265730.021
peripheral nervous system developmentGO:000742220.021
cellular protein catabolic processGO:00442572610.021
female gamete generationGO:000729220.020
negative regulation of cellular amino acid metabolic processGO:004576320.020
maintenance of locationGO:00512351120.020
organic acid catabolic processGO:0016054710.020
locomotory behaviorGO:000762610.020
nucleoside triphosphate catabolic processGO:00091433940.020
cellular ion homeostasisGO:00068731680.020
divalent metal ion transportGO:00708381520.020
regulation of sequence specific dna binding transcription factor activityGO:00510902110.020
protein localization to organelleGO:00333652800.019
organ formationGO:004864530.019
glycosyl compound catabolic processGO:19016584130.019
metal ion transportGO:00300012720.019
nitrogen compound transportGO:00717051910.019
ribonucleoside triphosphate metabolic processGO:00091994120.019
regulation of protein kinase activityGO:00458592890.019
regulation of kinase activityGO:00435493140.019
cellular calcium ion homeostasisGO:00068741170.019
transmembrane transportGO:00550853990.019
regulation of purine nucleotide metabolic processGO:19005422640.019
sequestering of metal ionGO:0051238240.019
regulation of dna metabolic processGO:00510521530.019
negative regulation of cellular component organizationGO:00511292350.019
response to hormoneGO:00097251750.018
Human
regulation of reactive oxygen species metabolic processGO:2000377410.018
Human
purine nucleoside triphosphate catabolic processGO:00091463920.018
cellular response to dna damage stimulusGO:00069743790.018
cell projection organizationGO:00300302520.018
ion homeostasisGO:00508012300.018
protein maturationGO:00516042330.018
cell divisionGO:00513011680.018
histone modificationGO:00165702510.018
regulation of protein transportGO:00512232130.018
regulation of mitotic cell cycleGO:00073461890.018
nucleoside catabolic processGO:00091644080.018
positive regulation of apoptotic processGO:00430652460.018
inorganic cation transmembrane transportGO:00986621940.018
chromatin modificationGO:00165682980.018
neurological system processGO:00508771630.018
segmentationGO:003528240.018
cellular component morphogenesisGO:00329893140.018
endomembrane system organizationGO:00102561960.018
signal transduction by phosphorylationGO:00230142970.017
modification dependent protein catabolic processGO:00199412090.017
generation of precursor metabolites and energyGO:0006091680.017
small gtpase mediated signal transductionGO:0007264780.017
ion transmembrane transportGO:00342203380.017
developmental programmed cell deathGO:001062330.017
phospholipid metabolic processGO:0006644990.017
negative regulation of multicellular organismal processGO:00512413170.017
divalent inorganic cation transportGO:00725111580.017
positive regulation of programmed cell deathGO:00430682490.017
cellular macromolecular complex assemblyGO:00346223240.017
regulation of mapk cascadeGO:00434082620.017
alcohol metabolic processGO:00060661140.017
negative regulation of protein modification processGO:00314002000.017
response to cytokineGO:00340972320.017
enzyme linked receptor protein signaling pathwayGO:00071673030.017
Human
purine nucleotide catabolic processGO:00061954050.017
peptidyl lysine modificationGO:00182051440.017
negative regulation of intracellular signal transductionGO:19025321830.017
atp metabolic processGO:00460341760.017
purine ribonucleoside triphosphate catabolic processGO:00092073910.016
purine ribonucleoside triphosphate metabolic processGO:00092054110.016
response to lipidGO:00339932060.016
Human
negative regulation of programmed cell deathGO:00430693210.016
Human
divalent inorganic cation homeostasisGO:00725071360.016
positive regulation of kinase activityGO:00336742040.016
organophosphate catabolic processGO:00464344300.016
regulation of peptidase activityGO:00525471800.016
cellular response to organic cyclic compoundGO:00714071270.016
response to decreased oxygen levelsGO:0036293960.016
Human
regulation of homeostatic processGO:00328441210.016
regulation of cytoplasmic transportGO:19036491490.016
ribonucleoside monophosphate metabolic processGO:00091611870.016
anatomical structure formation involved in morphogenesisGO:00486462840.016
carbohydrate metabolic processGO:00059752070.016
Human
positive regulation of cell deathGO:00109422630.016
single organism carbohydrate metabolic processGO:00447231930.016
Human
ribonucleotide catabolic processGO:00092614050.016
organic hydroxy compound metabolic processGO:19016151470.016
purine ribonucleotide catabolic processGO:00091544040.016
calcium ion transportGO:00068161470.016
organic acid biosynthetic processGO:0016053970.016
Human
anterior posterior axis specificationGO:000994820.016
ribonucleoside monophosphate catabolic processGO:00091581580.016
intracellular protein transportGO:00068862700.015
blastoderm segmentationGO:000735020.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
positive regulation of cell cycleGO:00457871400.015
cellular cation homeostasisGO:00300031630.015
purine nucleoside catabolic processGO:00061523980.015
carbohydrate derivative biosynthetic processGO:19011372070.015
regulation of cellular component movementGO:00512703340.015
epithelium developmentGO:00604292270.015
negative regulation of reactive oxygen species metabolic processGO:2000378110.015
regulation of protein processingGO:00706131500.015
protein dephosphorylationGO:0006470810.015
oocyte differentiationGO:000999420.015
nucleoside monophosphate metabolic processGO:00091231910.015
neural tube formationGO:000184130.015
regulation of secretionGO:00510461940.015
cellular modified amino acid metabolic processGO:0006575640.015
positive regulation of catabolic processGO:00098963100.015
positive regulation of protein kinase activityGO:00458601900.015
cellular metal ion homeostasisGO:00068751460.015
microtubule based processGO:00070172100.015
oocyte developmentGO:004859910.015
regulation of metal ion transportGO:00109591200.015
small molecule catabolic processGO:0044282920.015
regulation of cytokine productionGO:00018172320.014
cell morphogenesisGO:00009022960.014
autophagyGO:0006914880.014
cytokine productionGO:00018162470.014
regulation of protein modification by small protein conjugation or removalGO:19033201070.014
defense responseGO:00069523150.014
positive regulation of nucleoside metabolic processGO:00459791860.014
anion transportGO:00068201610.014
positive regulation of hydrolase activityGO:00513453310.014
modification dependent macromolecule catabolic processGO:00436322120.014
negative regulation of cell deathGO:00605483450.014
Human
cellular macromolecule catabolic processGO:00442653800.014
regulation of anatomical structure morphogenesisGO:00226032860.014
response to oxidative stressGO:00069791210.014
morphogenesis of embryonic epitheliumGO:001633140.014
glycerophospholipid metabolic processGO:0006650840.014
protein processingGO:00164852260.014
actin filament based processGO:00300292240.014
intrinsic apoptotic signaling pathwayGO:00971931270.014
response to oxygen levelsGO:00704821000.014
Human
regulation of nucleoside metabolic processGO:00091182090.014
cell cell signalingGO:00072671550.014
cofactor metabolic processGO:0051186870.014
Human
cell developmentGO:00484683280.014
regulation of establishment of protein localizationGO:00702012420.014
growthGO:00400072020.014
negative regulation of hydrolase activityGO:00513461820.014
negative regulation of transferase activityGO:00513481240.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
regulation of transmembrane transportGO:00347621390.013
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.013
cellular response to hormone stimulusGO:00328701250.013
Human
positive regulation of transferase activityGO:00513472270.013
regulation of vesicle mediated transportGO:00606271300.013
long term memoryGO:000761620.013
positive regulation of cellular catabolic processGO:00313312840.013
regulation of protein serine threonine kinase activityGO:00719001790.013
regenerationGO:003109940.013
regulation of protein ubiquitinationGO:0031396950.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
response to biotic stimulusGO:00096072760.013
immune responseGO:00069553070.013
regulation of synaptic transmission dopaminergicGO:003222540.013
myeloid cell differentiationGO:00300991170.013
response to axon injuryGO:004867810.013
embryonic forelimb morphogenesisGO:003511540.013
regulation of membrane potentialGO:0042391950.013
inorganic ion transmembrane transportGO:00986602310.013
protein targetingGO:00066051870.013
regulation of peptidyl serine phosphorylationGO:0033135500.013
regulation of cell differentiationGO:00455953930.013
tube closureGO:006060630.012
protein destabilizationGO:0031648120.012
regulation of ion transmembrane transportGO:00347651320.012
response to organonitrogen compoundGO:00102431560.012
Human
negative regulation of protein phosphorylationGO:00019331400.012
embryonic epithelial tube formationGO:000183840.012
negative regulation of transportGO:00510511760.012
regulation of meiotic cell cycleGO:005144540.012
regulation of bindingGO:00510981110.012
glutathione metabolic processGO:0006749200.012
regulation of protein maturationGO:19033171500.012
response to hypoxiaGO:0001666960.012
Human
regulation of protein bindingGO:0043393660.012
protein localization to membraneGO:00726571600.012
positive regulation of nucleotide metabolic processGO:00459812300.012
organelle assemblyGO:00709251760.012
regulation of anatomical structure sizeGO:00900661010.012
sensory perception of painGO:001923340.012
anterior posterior axis specification embryoGO:000859520.012
cellular response to decreased oxygen levelsGO:0036294510.012
Human
meiotic chromosome segregationGO:004513240.012
regulation of calcium ion transportGO:0051924790.012
cellular divalent inorganic cation homeostasisGO:00725031280.012
cell cycle phase transitionGO:00447701730.012
protein oligomerizationGO:00512591730.012
positive regulation of cell proliferationGO:00082843010.012
mitochondrion organizationGO:00070051560.012
purine ribonucleoside catabolic processGO:00461303980.012
cellular protein complex assemblyGO:00436231880.012
mitotic cell cycle phase transitionGO:00447721620.012
nuclear divisionGO:00002801280.012
nuclear transportGO:00511691790.012
secretionGO:00469032540.012
innate immune responseGO:00450871780.012
cellular response to organonitrogen compoundGO:00714171240.012
Human
rhythmic behaviorGO:000762220.012
regulation of growthGO:00400081650.012
adult locomotory behaviorGO:000834410.011
ubiquitin dependent protein catabolic processGO:00065112060.011
negative regulation of cell cycleGO:00457861930.011
positive regulation of secretionGO:00510471160.011
spermatid differentiationGO:004851540.011
microtubule cytoskeleton organizationGO:00002261760.011
synaptic vesicle exocytosisGO:001607930.011
behavioral response to ethanolGO:004814920.011
protein acylationGO:00435431380.011
cardiac muscle cell contractionGO:008600340.011
plasma membrane organizationGO:00070091150.011
alpha amino acid metabolic processGO:1901605720.011
peptidyl tyrosine phosphorylationGO:00181081700.011
positive regulation of cellular component movementGO:00512721810.011
dna repairGO:00062811980.011
regulation of cell motilityGO:20001452990.011
regulation of cell cycle phase transitionGO:19019871260.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
primary neural tube formationGO:001402030.011
neurogenesisGO:00220081690.011
cytosolic calcium ion homeostasisGO:0051480890.011
tissue migrationGO:00901301190.011
generation of neuronsGO:00486991520.011
cell fate determinationGO:000170930.011
negative regulation of protein processingGO:00109551420.011
establishment of protein localization to membraneGO:00901501210.011
regulation of wnt signaling pathwayGO:00301111230.011
cellular component disassemblyGO:0022411920.011
rab protein signal transductionGO:003248240.011
cell type specific apoptotic processGO:00972851250.011
monocarboxylic acid biosynthetic processGO:0072330670.011
Human
neuron differentiationGO:00301821380.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
positive regulation of cellular component biogenesisGO:00440891580.011
associative learningGO:000830610.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
response to growth factorGO:00708482050.011
response to external biotic stimulusGO:00432072610.011
epithelium migrationGO:00901321190.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.010
cation transmembrane transportGO:00986552380.010
nucleoside phosphate biosynthetic processGO:19012931090.010
cellular response to cytokine stimulusGO:00713451810.010
organic anion transportGO:00157111030.010
wnt signaling pathwayGO:00160551560.010
positive regulation of purine nucleotide metabolic processGO:19005442270.010
lipid catabolic processGO:0016042840.010
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.010
regulation of cytoskeleton organizationGO:00514931770.010
glycerolipid biosynthetic processGO:0045017510.010
energy derivation by oxidation of organic compoundsGO:0015980430.010
somatic muscle developmentGO:000752510.010
neural tube closureGO:000184330.010
chromosome segregationGO:00070591140.010
sulfur compound metabolic processGO:00067901010.010
Human
regulation of synaptic vesicle exocytosisGO:200030020.010
spermatid developmentGO:000728640.010
metencephalon developmentGO:002203720.010
negative regulation of peptidase activityGO:0010466910.010
regulation of cell migrationGO:00303342890.010
nucleocytoplasmic transportGO:00069131760.010
negative regulation of dna metabolic processGO:0051053570.010
mapk cascadeGO:00001652880.010
cellular response to growth factor stimulusGO:00713631970.010
negative regulation of kinase activityGO:00336731060.010
brain developmentGO:0007420970.010
proteasomal protein catabolic processGO:00104981760.010

PDK2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.168
inherited metabolic disorderDOID:6552420.168
central nervous system diseaseDOID:3311860.035
nervous system diseaseDOID:8634310.035
neurodegenerative diseaseDOID:12891020.019
disease of cellular proliferationDOID:145661740.016
amino acid metabolic disorderDOID:9252500.015
organ system cancerDOID:00506861640.014
cancerDOID:1621670.014
sensory system diseaseDOID:00501552030.014
cardiovascular system diseaseDOID:12871060.014
eye and adnexa diseaseDOID:14921500.012
eye diseaseDOID:56141490.012
synucleinopathyDOID:0050890220.010
musculoskeletal system diseaseDOID:172230.010