Homo sapiens

80 known processes

HIST2H4B

histone cluster 2, H4b

(Aliases: HIST1H4C,HIST1H4B,HIST1H4A,HIST4H4,HIST1H4F,HIST1H4E,HIST1H4D,HIST1H4K,HIST1H4J,H4/o,HIST1H4H,HIST1H4L,HIST1H4I,HIST2H4A)

HIST2H4B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna replication dependent nucleosome assemblyGO:0006335320.621
negative regulation of megakaryocyte differentiationGO:0045653160.433
dna replication independent nucleosome assemblyGO:0006336270.290
dna replication dependent nucleosome organizationGO:0034723320.230
chromatin assemblyGO:0031497610.220
chromatin assembly or disassemblyGO:0006333780.216
dna replication independent nucleosome organizationGO:0034724270.212
nucleosome assemblyGO:0006334500.211
chromatin organizationGO:00063253510.175
nucleosome organizationGO:0034728660.156
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.128
regulation of megakaryocyte differentiationGO:0045652220.120
dna conformation changeGO:00711031130.114
cellular macromolecular complex assemblyGO:00346223240.099
protein dna complex assemblyGO:0065004640.091
regulation of hematopoietic progenitor cell differentiationGO:1901532240.089
cellular response to dna damage stimulusGO:00069743790.081
myeloid cell differentiationGO:00300991170.080
protein dna complex subunit organizationGO:0071824800.075
negative regulation of immune system processGO:00026831360.071
dna repairGO:00062811980.069
regulation of myeloid cell differentiationGO:0045637810.066
dna packagingGO:0006323770.066
negative regulation of multicellular organismal processGO:00512413170.065
negative regulation of myeloid cell differentiationGO:0045638420.060
post embryonic developmentGO:000979120.057
hematopoietic or lymphoid organ developmentGO:00485341860.053
histone modificationGO:00165702510.052
negative regulation of developmental processGO:00510932470.049
hemopoiesisGO:00300971800.048
cellular amino acid metabolic processGO:00065201160.047
macromolecule methylationGO:0043414970.045
anatomical structure formation involved in morphogenesisGO:00486462840.044
regulation of cell differentiationGO:00455953930.042
immune system developmentGO:00025201950.042
histone methylationGO:0016571600.037
cellular ketone metabolic processGO:0042180800.037
regulation of cellular amino acid metabolic processGO:000652160.037
megakaryocyte differentiationGO:0030219250.036
regulation of cellular amine metabolic processGO:0033238110.036
regulation of cellular ketone metabolic processGO:0010565500.035
cellular amine metabolic processGO:0044106410.035
chromatin modificationGO:00165682980.034
determination of adult lifespanGO:000834020.034
rna processingGO:00063962550.034
amine metabolic processGO:0009308440.034
positive regulation of cellular amino acid metabolic processGO:004576430.034
histone h3 k79 methylationGO:003472920.033
multicellular organismal agingGO:001025930.033
negative regulation of cell differentiationGO:00455961710.032
methylationGO:00322591060.032
response to abiotic stimulusGO:00096283360.030
protein methylationGO:0006479740.030
positive regulation of cellular amine metabolic processGO:003324070.029
defense responseGO:00069523150.029
covalent chromatin modificationGO:00165692540.028
mrna metabolic processGO:00160711750.028
negative regulation of cellular protein metabolic processGO:00322693530.028
negative regulation of hematopoietic progenitor cell differentiationGO:1901533180.028
female gamete generationGO:000729220.028
hematopoietic progenitor cell differentiationGO:0002244380.028
immune responseGO:00069553070.028
system processGO:00030083490.027
response to biotic stimulusGO:00096072760.026
negative regulation of protein metabolic processGO:00512483910.026
cellular macromolecule catabolic processGO:00442653800.026
oogenesisGO:004847720.025
segmentationGO:003528240.025
cell cycle checkpointGO:00000751170.025
negative regulation of catalytic activityGO:00430863350.025
neuromuscular junction developmentGO:000752830.024
innate immune responseGO:00450871780.024
regulation of proteolysisGO:00301622930.024
mrna processingGO:00063971330.024
protein alkylationGO:0008213740.023
locomotory behaviorGO:000762610.023
cytoplasmic transportGO:00164823790.023
response to radiationGO:00093141510.023
protein catabolic processGO:00301633250.022
histone lysine methylationGO:0034968500.022
ras protein signal transductionGO:0007265730.022
positive regulation of hydrolase activityGO:00513453310.022
purine ribonucleoside metabolic processGO:00461284370.022
memoryGO:000761330.022
cellular response to abiotic stimulusGO:00712141170.022
nucleoside triphosphate metabolic processGO:00091414220.022
regulation of cell cycleGO:00517263930.021
small gtpase mediated signal transductionGO:0007264780.021
protein localization to organelleGO:00333652800.021
protein maturationGO:00516042330.021
purine ribonucleoside triphosphate metabolic processGO:00092054110.021
response to uvGO:0009411730.021
organophosphate catabolic processGO:00464344300.021
response to other organismGO:00517072610.021
protein complex disassemblyGO:0043241520.021
regulation of gene expression epigeneticGO:0040029730.020
purine nucleoside triphosphate metabolic processGO:00091444120.020
response to oxygen containing compoundGO:19017003690.020
positive regulation of cellular component organizationGO:00511303760.020
regenerationGO:003109940.020
positive regulation of phosphorylationGO:00423273940.020
purine containing compound catabolic processGO:00725234110.020
purine nucleoside triphosphate catabolic processGO:00091463920.020
single organism cellular localizationGO:19025803320.020
negative regulation of phosphorus metabolic processGO:00105632670.020
cellular component disassemblyGO:0022411920.020
ribonucleotide catabolic processGO:00092614050.020
cellular protein catabolic processGO:00442572610.019
ribonucleoside triphosphate catabolic processGO:00092033910.019
nucleotide catabolic processGO:00091664080.019
ribonucleoside triphosphate metabolic processGO:00091994120.019
negative regulation of programmed cell deathGO:00430693210.019
negative regulation of cell deathGO:00605483450.019
response to external biotic stimulusGO:00432072610.019
proteolysis involved in cellular protein catabolic processGO:00516032440.019
lipid metabolic processGO:00066293810.019
protein processingGO:00164852260.019
regulation of cell cycle processGO:00105642660.019
purine nucleoside catabolic processGO:00061523980.019
transmembrane transportGO:00550853990.019
glycosyl compound catabolic processGO:19016584130.018
negative regulation of phosphate metabolic processGO:00459362670.018
blastoderm segmentationGO:000735020.018
cellular lipid metabolic processGO:00442553030.018
ribonucleoside catabolic processGO:00424544060.018
cellular response to endogenous stimulusGO:00714953360.018
nucleoside triphosphate catabolic processGO:00091433940.018
regulation of transferase activityGO:00513383550.018
gene silencingGO:0016458490.018
purine nucleotide catabolic processGO:00061954050.018
peripheral nervous system developmentGO:000742220.018
purine ribonucleoside catabolic processGO:00461303980.018
single organism membrane organizationGO:00448022680.018
nucleoside phosphate catabolic processGO:19012924120.018
apoptotic signaling pathwayGO:00971902680.018
positive regulation of transportGO:00510503360.018
signal transduction by phosphorylationGO:00230142970.018
purine ribonucleoside triphosphate catabolic processGO:00092073910.018
purine ribonucleotide catabolic processGO:00091544040.017
regulation of protein localizationGO:00328802960.017
positive regulation of catabolic processGO:00098963100.017
negative regulation of cellular component organizationGO:00511292350.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
regulation of cellular response to stressGO:00801352440.017
modification dependent macromolecule catabolic processGO:00436322120.017
dephosphorylationGO:00163112090.017
anterior posterior axis specificationGO:000994820.017
cation transportGO:00068123310.017
positive regulation of immune system processGO:00026842830.017
negative regulation of apoptotic processGO:00430663160.017
biological adhesionGO:00226103310.017
intracellular protein transportGO:00068862700.017
response to light stimulusGO:0009416870.017
regulation of protein kinase activityGO:00458592890.017
positive regulation of organelle organizationGO:00106381950.017
actin filament based processGO:00300292240.017
cellular response to radiationGO:0071478650.017
chemical homeostasisGO:00488783060.017
vesicle mediated transportGO:00161923710.016
regulation of response to external stimulusGO:00321012220.016
cell morphogenesisGO:00009022960.016
regulation of kinase activityGO:00435493140.016
mitotic cell cycleGO:00002783260.016
regulation of cellular component movementGO:00512703340.016
regulation of establishment of protein localizationGO:00702012420.016
modification dependent protein catabolic processGO:00199412090.016
mitotic cell cycle processGO:19030472860.016
nucleoside catabolic processGO:00091644080.016
negative regulation of cellular amine metabolic processGO:003323930.016
spermatid differentiationGO:004851540.016
posttranscriptional regulation of gene expressionGO:00106082130.016
positive regulation of cellular catabolic processGO:00313312840.016
negative regulation of cell cycleGO:00457861930.016
defense response to other organismGO:00985421290.016
ion homeostasisGO:00508012300.016
organ formationGO:004864530.016
oocyte developmentGO:004859910.016
membrane organizationGO:00610242920.016
cell adhesionGO:00071553250.015
regulation of protein transportGO:00512232130.015
regulation of nucleotide metabolic processGO:00061402690.015
mapk cascadeGO:00001652880.015
cell fate determinationGO:000170930.015
organonitrogen compound biosynthetic processGO:19015662000.015
negative regulation of protein modification processGO:00314002000.015
motor neuron axon guidanceGO:000804520.015
maintenance of locationGO:00512351120.015
compound eye developmentGO:004874910.015
oocyte differentiationGO:000999420.015
protein ubiquitinationGO:00165673140.015
regulation of locomotionGO:00400123290.015
cellular component morphogenesisGO:00329893140.015
cellular response to oxygen containing compoundGO:19017012760.015
embryonic epithelial tube formationGO:000183840.015
regulation of purine nucleotide metabolic processGO:19005422640.015
regulation of protein catabolic processGO:00421761550.015
associative learningGO:000830610.015
protein modification by small protein conjugationGO:00324463420.015
regulation of anatomical structure morphogenesisGO:00226032860.015
positive regulation of cell deathGO:00109422630.015
protein targetingGO:00066051870.015
rho protein signal transductionGO:0007266260.015
positive regulation of cell proliferationGO:00082843010.015
regulation of intracellular transportGO:00323861950.014
positive regulation of programmed cell deathGO:00430682490.014
negative regulation of intracellular signal transductionGO:19025321830.014
regulation of mitotic cell cycleGO:00073461890.014
cellular response to uvGO:0034644320.014
morphogenesis of embryonic epitheliumGO:001633140.014
regulation of cellular component biogenesisGO:00440872810.014
regulation of protein maturationGO:19033171500.014
reactive oxygen species biosynthetic processGO:190340940.014
growthGO:00400072020.014
response to bacteriumGO:00096171440.014
cell growthGO:00160491600.014
negative regulation of proteolysisGO:00458611320.014
ubiquitin dependent protein catabolic processGO:00065112060.014
oxidation reduction processGO:00551143960.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
regulation of cell motilityGO:20001452990.014
regulation of cell migrationGO:00303342890.014
establishment of protein localization to organelleGO:00725941720.014
adult locomotory behaviorGO:000834410.014
negative regulation of protein processingGO:00109551420.014
spermatid developmentGO:000728640.014
metal ion transportGO:00300012720.014
enzyme linked receptor protein signaling pathwayGO:00071673030.014
negative regulation of hydrolase activityGO:00513461820.014
regulation of gene silencingGO:0060968240.014
positive regulation of apoptotic processGO:00430652460.014
carbohydrate metabolic processGO:00059752070.014
tissue regenerationGO:004224630.014
positive regulation of transferase activityGO:00513472270.014
regulation of cytokine productionGO:00018172320.014
nervous system developmentGO:00073992930.014
proteasomal protein catabolic processGO:00104981760.014
cell projection organizationGO:00300302520.014
regulation of mapk cascadeGO:00434082620.014
protein oligomerizationGO:00512591730.014
tripartite regional subdivisionGO:000735120.013
carbohydrate derivative biosynthetic processGO:19011372070.013
macromolecular complex disassemblyGO:0032984600.013
organophosphate biosynthetic processGO:00904071630.013
response to cytokineGO:00340972320.013
guanosine containing compound catabolic processGO:19010692390.013
regulation of protein processingGO:00706131500.013
mitochondrion organizationGO:00070051560.013
positive regulation of nucleotide metabolic processGO:00459812300.013
reactive oxygen species metabolic processGO:0072593750.013
regulation of growthGO:00400081650.013
symbiosis encompassing mutualism through parasitismGO:00444031560.013
neurological system processGO:00508771630.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
regulation of immune responseGO:00507762010.013
rhythmic behaviorGO:000762220.013
positive regulation of synaptic transmissionGO:005080640.013
positive regulation of protein phosphorylationGO:00019343130.013
reactive nitrogen species metabolic processGO:200105730.013
hindbrain developmentGO:003090230.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
negative regulation of phosphorylationGO:00423261740.013
negative regulation of protein maturationGO:19033181420.013
cell cycle phase transitionGO:00447701730.013
epithelium developmentGO:00604292270.013
nuclear transportGO:00511691790.013
nerve developmentGO:002167540.013
microtubule based processGO:00070172100.013
monocarboxylic acid metabolic processGO:00327871850.013
neurotransmitter secretionGO:000726940.013
syncytium formation by plasma membrane fusionGO:000076820.013
reproductive processGO:00224141060.013
nucleocytoplasmic transportGO:00069131760.013
negative regulation of cell proliferationGO:00082852280.012
regulation of neural precursor cell proliferationGO:200017740.012
interspecies interaction between organismsGO:00444191560.012
single organism carbohydrate metabolic processGO:00447231930.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
endomembrane system organizationGO:00102561960.012
regulation of endopeptidase activityGO:00525481700.012
anterior posterior axis specification embryoGO:000859520.012
response to fungusGO:000962040.012
secretion by cellGO:00329402260.012
gtp metabolic processGO:00460392390.012
photoreceptor cell differentiationGO:004653020.012
cation homeostasisGO:00550801890.012
circadian behaviorGO:004851220.012
positive regulation of kinase activityGO:00336742040.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
secretionGO:00469032540.012
cellular protein complex assemblyGO:00436231880.012
guanosine containing compound metabolic processGO:19010682440.012
metencephalon developmentGO:002203720.012
stem cell divisionGO:001714520.012
cytokine productionGO:00018162470.012
regulation of apoptotic signaling pathwayGO:20012331750.012
ion transmembrane transportGO:00342203380.012
actin cytoskeleton organizationGO:00300362070.012
regulation of synaptic plasticityGO:004816730.012
lipid biosynthetic processGO:00086101770.012
regulation of secretionGO:00510461940.012
inner ear morphogenesisGO:004247240.012
single organism reproductive processGO:0044702980.012
response to axon injuryGO:004867810.012
positive regulation of nucleoside metabolic processGO:00459791860.012
multi organism cellular processGO:00447641560.012
postreplication repairGO:0006301120.012
positive regulation of cellular component movementGO:00512721810.012
regulation of cytoskeleton organizationGO:00514931770.012
positive regulation of protein kinase activityGO:00458601900.012
regulation of purine nucleotide catabolic processGO:00331212050.011
visual behaviorGO:000763220.011
regulation of multi organism processGO:00439001570.011
regulation of cell growthGO:00015581350.011
response to growth factorGO:00708482050.011
positive regulation of developmental processGO:00510943140.011
divalent metal ion transportGO:00708381520.011
limbic system developmentGO:002176130.011
cellular response to cytokine stimulusGO:00713451810.011
response to organic cyclic compoundGO:00140702040.011
regulation of peptidase activityGO:00525471800.011
cellular homeostasisGO:00197251960.011
anion transportGO:00068201610.011
cellular chemical homeostasisGO:00550821800.011
positive regulation of cell migrationGO:00303351720.011
cell divisionGO:00513011680.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
nucleoside monophosphate metabolic processGO:00091231910.011
cell developmentGO:00484683280.011
cellular ion homeostasisGO:00068731680.011
cellular cation homeostasisGO:00300031630.011
nitrogen compound transportGO:00717051910.011
morphogenesis of a polarized epitheliumGO:000173830.011
matingGO:000761810.011
response to nitrogen compoundGO:19016981840.011
cell activationGO:00017752130.011
positive regulation of locomotionGO:00400171860.011
cardiac muscle cell contractionGO:008600340.011
sequestering of metal ionGO:0051238240.011
thymus developmentGO:004853830.011
t cell differentiation in thymusGO:003307740.011
regulation of dna metabolic processGO:00510521530.011
atp metabolic processGO:00460341760.011
organelle assemblyGO:00709251760.011
gtp catabolic processGO:00061842370.011
negative regulation of organelle organizationGO:00106391260.011
myoblast fusionGO:000752010.011
neural tube formationGO:000184130.011
regulation of defense responseGO:00313471540.011
protein localization to membraneGO:00726571600.011
mitotic cell cycle phase transitionGO:00447721620.011
small molecule biosynthetic processGO:00442831570.011
response to woundingGO:00096111680.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
wnt signaling pathwayGO:00160551560.011
negative regulation of cell cycle processGO:00109481210.011
regulation of cell morphogenesisGO:00226041530.011
regulation of nucleoside metabolic processGO:00091182090.011
glycoprotein metabolic processGO:00091001100.011
negative regulation of transportGO:00510511760.011
negative regulation of catabolic processGO:00098951040.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
dna damage checkpointGO:0000077680.011
negative regulation of transferase activityGO:00513481240.010
regulation of nucleotide catabolic processGO:00308112050.010
regulation of cytoplasmic transportGO:19036491490.010
negative regulation of protein phosphorylationGO:00019331400.010
response to lipidGO:00339932060.010
metal ion homeostasisGO:00550651690.010
cellular response to growth factor stimulusGO:00713631970.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
positive regulation of nucleotide catabolic processGO:00308131850.010
regulation of secretion by cellGO:19035301770.010
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.010
neuroblast proliferationGO:000740540.010
microtubule cytoskeleton organizationGO:00002261760.010
primary neural tube formationGO:001402030.010
glial cell migrationGO:000834740.010
positive regulation of cellular component biogenesisGO:00440891580.010
salivary gland morphogenesisGO:000743540.010
specification of organ identityGO:001009230.010
regulation of protein complex assemblyGO:00432541470.010
rna interferenceGO:001624640.010
peptidyl tyrosine modificationGO:00182121700.010
positive regulation of purine nucleotide catabolic processGO:00331231850.010
positive regulation of neural precursor cell proliferationGO:200017920.010
sequestering of calcium ionGO:0051208170.010
positive regulation of cell differentiationGO:00455972110.010
organelle fissionGO:00482851490.010
regulation of protein serine threonine kinase activityGO:00719001790.010
regulation of small gtpase mediated signal transductionGO:00510561560.010
calcium ion transportGO:00068161470.010
inorganic ion transmembrane transportGO:00986602310.010
tube closureGO:006060630.010
cardiovascular system developmentGO:00723582620.010
developmental programmed cell deathGO:001062330.010

HIST2H4B disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.029
nervous system diseaseDOID:8634310.023
sensory system diseaseDOID:00501552030.023
musculoskeletal system diseaseDOID:172230.022
inherited metabolic disorderDOID:6552420.018
central nervous system diseaseDOID:3311860.017
eye and adnexa diseaseDOID:14921500.017
eye diseaseDOID:56141490.017
disease of cellular proliferationDOID:145661740.016
cancerDOID:1621670.015
organ system cancerDOID:00506861640.015
connective tissue diseaseDOID:651090.014
immune system diseaseDOID:29141550.013
bone diseaseDOID:0080001880.013
retinal diseaseDOID:56791180.012
myopathyDOID:4231040.012
muscular diseaseDOID:00800001140.012
muscle tissue diseaseDOID:661130.012
neurodegenerative diseaseDOID:12891020.012
brain diseaseDOID:936730.010