Homo sapiens

143 known processes

PDK4

pyruvate dehydrogenase kinase, isozyme 4

(Aliases: FLJ40832)

PDK4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
lipid metabolic processGO:00066293810.322
cellular lipid metabolic processGO:00442553030.288
cellular ketone metabolic processGO:0042180800.239
cellular amino acid metabolic processGO:00065201160.216
monocarboxylic acid metabolic processGO:00327871850.200
response to abiotic stimulusGO:00096283360.171
Human
amine metabolic processGO:0009308440.166
cellular amine metabolic processGO:0044106410.150
regulation of cellular amine metabolic processGO:0033238110.143
positive regulation of phosphorylationGO:00423273940.140
response to oxygen containing compoundGO:19017003690.136
oxidation reduction processGO:00551143960.133
positive regulation of cellular amine metabolic processGO:003324070.123
regulation of cellular ketone metabolic processGO:0010565500.123
cellular response to oxygen containing compoundGO:19017012760.116
fatty acid metabolic processGO:00066311150.111
regulation of cellular amino acid metabolic processGO:000652160.108
positive regulation of protein phosphorylationGO:00019343130.103
system processGO:00030083490.088
negative regulation of multicellular organismal processGO:00512413170.082
defense responseGO:00069523150.081
regulation of transferase activityGO:00513383550.078
positive regulation of cellular amino acid metabolic processGO:004576430.077
signal transduction by phosphorylationGO:00230142970.077
circulatory system developmentGO:00723592620.077
response to organic cyclic compoundGO:00140702040.074
regulation of cytokine productionGO:00018172320.074
lipid biosynthetic processGO:00086101770.072
cation transportGO:00068123310.071
response to nitrogen compoundGO:19016981840.071
post embryonic developmentGO:000979120.070
organic hydroxy compound metabolic processGO:19016151470.068
cellular response to endogenous stimulusGO:00714953360.066
regulation of cell differentiationGO:00455953930.066
immune responseGO:00069553070.066
response to hormoneGO:00097251750.065
positive regulation of transportGO:00510503360.065
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.063
regulation of cell migrationGO:00303342890.062
carbohydrate metabolic processGO:00059752070.062
nucleoside triphosphate metabolic processGO:00091414220.061
mapk cascadeGO:00001652880.060
regulation of cellular component movementGO:00512703340.059
cell adhesionGO:00071553250.059
long chain fatty acid metabolic processGO:0001676300.059
cytokine productionGO:00018162470.058
response to lipidGO:00339932060.058
negative regulation of catalytic activityGO:00430863350.057
multicellular organismal agingGO:001025930.057
negative regulation of cell deathGO:00605483450.056
chemical homeostasisGO:00488783060.056
regulation of mapk cascadeGO:00434082620.054
nucleoside phosphate catabolic processGO:19012924120.054
metal ion transportGO:00300012720.054
regulation of response to external stimulusGO:00321012220.054
cytoplasmic transportGO:00164823790.053
response to biotic stimulusGO:00096072760.053
regulation of locomotionGO:00400123290.053
enzyme linked receptor protein signaling pathwayGO:00071673030.053
single organism carbohydrate metabolic processGO:00447231930.053
positive regulation of mapk cascadeGO:00434101900.053
positive regulation of developmental processGO:00510943140.052
transmembrane transportGO:00550853990.052
determination of adult lifespanGO:000834020.051
negative regulation of protein metabolic processGO:00512483910.050
biological adhesionGO:00226103310.050
negative regulation of programmed cell deathGO:00430693210.049
purine ribonucleoside metabolic processGO:00461284370.049
negative regulation of phosphorus metabolic processGO:00105632670.049
ion homeostasisGO:00508012300.048
purine containing compound catabolic processGO:00725234110.048
secretionGO:00469032540.047
locomotory behaviorGO:000762610.047
alcohol metabolic processGO:00060661140.047
reactive oxygen species metabolic processGO:0072593750.047
nervous system developmentGO:00073992930.047
negative regulation of apoptotic processGO:00430663160.046
small molecule biosynthetic processGO:00442831570.046
cardiovascular system developmentGO:00723582620.045
negative regulation of cell proliferationGO:00082852280.045
regulation of secretionGO:00510461940.045
regulation of protein kinase activityGO:00458592890.044
regulation of cell motilityGO:20001452990.044
organophosphate catabolic processGO:00464344300.043
response to other organismGO:00517072610.043
negative regulation of cellular protein metabolic processGO:00322693530.043
organic anion transportGO:00157111030.043
purine nucleoside catabolic processGO:00061523980.043
vesicle mediated transportGO:00161923710.043
response to external biotic stimulusGO:00432072610.043
negative regulation of phosphate metabolic processGO:00459362670.043
organonitrogen compound biosynthetic processGO:19015662000.042
cellular component morphogenesisGO:00329893140.042
glycosyl compound catabolic processGO:19016584130.041
regulation of cellular response to stressGO:00801352440.041
blood circulationGO:00080151130.041
organic acid biosynthetic processGO:0016053970.041
nucleoside catabolic processGO:00091644080.041
ribonucleotide catabolic processGO:00092614050.041
nucleoside triphosphate catabolic processGO:00091433940.041
positive regulation of transferase activityGO:00513472270.041
response to cytokineGO:00340972320.041
female gamete generationGO:000729220.040
vasculature developmentGO:00019441810.040
purine ribonucleotide catabolic processGO:00091544040.040
regulation of kinase activityGO:00435493140.040
regenerationGO:003109940.040
positive regulation of kinase activityGO:00336742040.040
cellular homeostasisGO:00197251960.040
ribonucleoside triphosphate catabolic processGO:00092033910.039
epithelial cell differentiationGO:00308551410.039
nucleotide catabolic processGO:00091664080.039
peptidyl tyrosine modificationGO:00182121700.039
regulation of response to woundingGO:19030341010.039
ion transmembrane transportGO:00342203380.039
cellular chemical homeostasisGO:00550821800.039
oogenesisGO:004847720.039
purine nucleoside triphosphate catabolic processGO:00091463920.038
anion transportGO:00068201610.038
purine ribonucleoside catabolic processGO:00461303980.037
innate immune responseGO:00450871780.037
g protein coupled receptor signaling pathwayGO:00071862070.037
blood vessel morphogenesisGO:00485141620.037
ras protein signal transductionGO:0007265730.036
intracellular protein transportGO:00068862700.036
positive regulation of catabolic processGO:00098963100.036
regulation of protein localizationGO:00328802960.036
regulation of secretion by cellGO:19035301770.036
cellular response to organonitrogen compoundGO:00714171240.036
purine nucleoside triphosphate metabolic processGO:00091444120.035
regulation of anatomical structure morphogenesisGO:00226032860.035
angiogenesisGO:00015251470.035
purine nucleotide catabolic processGO:00061954050.035
protein localization to organelleGO:00333652800.035
purine ribonucleoside triphosphate metabolic processGO:00092054110.034
purine ribonucleoside triphosphate catabolic processGO:00092073910.034
peptidyl tyrosine phosphorylationGO:00181081700.034
protein ubiquitinationGO:00165673140.034
response to bacteriumGO:00096171440.034
cation homeostasisGO:00550801890.034
regulation of immune responseGO:00507762010.033
positive regulation of protein kinase activityGO:00458601900.033
blood vessel developmentGO:00015681720.033
secretion by cellGO:00329402260.033
positive regulation of hydrolase activityGO:00513453310.033
cellular response to nitrogen compoundGO:19016991440.033
epithelium developmentGO:00604292270.032
positive regulation of cell proliferationGO:00082843010.032
response to organonitrogen compoundGO:00102431560.032
cellular carbohydrate metabolic processGO:0044262840.032
cation transmembrane transportGO:00986552380.032
glycerolipid metabolic processGO:00464861070.032
single organism cellular localizationGO:19025803320.032
negative regulation of developmental processGO:00510932470.032
cellular response to hormone stimulusGO:00328701250.031
maintenance of locationGO:00512351120.031
response to inorganic substanceGO:00100351270.031
regulation of establishment of protein localizationGO:00702012420.031
ribonucleoside catabolic processGO:00424544060.031
cell developmentGO:00484683280.031
anatomical structure formation involved in morphogenesisGO:00486462840.031
ribonucleoside triphosphate metabolic processGO:00091994120.031
circulatory system processGO:00030131130.031
protein modification by small protein conjugationGO:00324463420.031
positive regulation of cellular component organizationGO:00511303760.030
response to woundingGO:00096111680.030
nitrogen compound transportGO:00717051910.030
positive regulation of immune system processGO:00026842830.030
lipid localizationGO:00108761060.030
response to decreased oxygen levelsGO:0036293960.030
Human
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.029
dephosphorylationGO:00163112090.029
steroid metabolic processGO:0008202940.029
endothelial cell migrationGO:0043542860.029
neurological system processGO:00508771630.029
protein targetingGO:00066051870.028
regulation of cell adhesionGO:00301551660.028
lipid modificationGO:0030258840.028
cell morphogenesisGO:00009022960.028
regulation of protein transportGO:00512232130.028
regulation of ion transportGO:00432691890.028
cellular ion homeostasisGO:00068731680.028
negative regulation of protein modification processGO:00314002000.028
cellular macromolecule catabolic processGO:00442653800.027
monovalent inorganic cation transportGO:00156721280.027
regulation of sequence specific dna binding transcription factor activityGO:00510902110.027
regulation of system processGO:00440571010.027
cellular cation homeostasisGO:00300031630.027
nucleocytoplasmic transportGO:00069131760.027
hemopoiesisGO:00300971800.027
regulation of defense responseGO:00313471540.027
positive regulation of apoptotic processGO:00430652460.027
regulation of reactive oxygen species metabolic processGO:2000377410.027
Human
segmentationGO:003528240.027
regulation of cell cycleGO:00517263930.027
cellular response to oxidative stressGO:0034599850.027
Human
cellular response to growth factor stimulusGO:00713631970.027
positive regulation of cell differentiationGO:00455972110.026
protein catabolic processGO:00301633250.026
neurogenesisGO:00220081690.026
nuclear transportGO:00511691790.026
positive regulation of cell motilityGO:20001471770.026
mitotic cell cycleGO:00002783260.026
positive regulation of cellular catabolic processGO:00313312840.026
negative regulation of cellular amino acid metabolic processGO:004576320.026
actin filament based processGO:00300292240.026
small gtpase mediated signal transductionGO:0007264780.025
regulation of proteolysisGO:00301622930.025
apoptotic signaling pathwayGO:00971902680.025
Human
negative regulation of transportGO:00510511760.025
protein maturationGO:00516042330.025
regulation of nucleotide metabolic processGO:00061402690.025
epithelium migrationGO:00901321190.025
positive regulation of secretion by cellGO:19035321080.024
positive regulation of cellular component movementGO:00512721810.024
negative regulation of intracellular signal transductionGO:19025321830.024
regulation of vasculature developmentGO:1901342970.024
cellular response to cytokine stimulusGO:00713451810.024
tissue migrationGO:00901301190.024
cellular metal ion homeostasisGO:00068751460.024
establishment of protein localization to organelleGO:00725941720.024
regulation of epithelial cell migrationGO:0010632930.024
regulation of cellular component biogenesisGO:00440872810.024
carbohydrate derivative biosynthetic processGO:19011372070.024
organophosphate biosynthetic processGO:00904071630.024
positive regulation of cell deathGO:00109422630.024
negative regulation of hydrolase activityGO:00513461820.024
hematopoietic or lymphoid organ developmentGO:00485341860.024
carboxylic acid biosynthetic processGO:0046394970.024
negative regulation of cellular component organizationGO:00511292350.024
epithelial cell proliferationGO:00506731280.024
acylglycerol metabolic processGO:0006639270.023
cell activationGO:00017752130.023
response to extracellular stimulusGO:0009991850.023
cellular macromolecular complex assemblyGO:00346223240.023
protein processingGO:00164852260.023
positive regulation of reactive oxygen species metabolic processGO:2000379240.023
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.023
negative regulation of cellular amine metabolic processGO:003323930.023
cell projection organizationGO:00300302520.023
regulation of peptidyl tyrosine phosphorylationGO:00507301080.023
rhythmic behaviorGO:000762220.023
regulation of purine nucleotide metabolic processGO:19005422640.023
cell substrate adhesionGO:00315891320.023
epithelial cell migrationGO:00106311190.023
regulation of homeostatic processGO:00328441210.023
i kappab kinase nf kappab signalingGO:00072491660.022
regulation of intracellular transportGO:00323861950.022
membrane organizationGO:00610242920.022
cellular response to organic cyclic compoundGO:00714071270.022
sulfur compound metabolic processGO:00067901010.022
inorganic cation transmembrane transportGO:00986621940.022
metal ion homeostasisGO:00550651690.022
positive regulation of programmed cell deathGO:00430682490.022
positive regulation of cytokine productionGO:00018191670.022
positive regulation of cell migrationGO:00303351720.022
neutral lipid metabolic processGO:0006638270.022
monosaccharide metabolic processGO:0005996740.021
response to oxygen levelsGO:00704821000.021
Human
cellular response to dna damage stimulusGO:00069743790.021
hindbrain developmentGO:003090230.021
guanosine containing compound metabolic processGO:19010682440.021
regulation of angiogenesisGO:0045765920.021
peripheral nervous system developmentGO:000742220.021
rho protein signal transductionGO:0007266260.021
negative regulation of locomotionGO:00400131180.021
positive regulation of secretionGO:00510471160.021
purine nucleoside monophosphate metabolic processGO:00091261860.021
cofactor metabolic processGO:0051186870.021
ribonucleoside monophosphate metabolic processGO:00091611870.021
negative regulation of phosphorylationGO:00423261740.021
purine ribonucleoside monophosphate metabolic processGO:00091671860.021
negative regulation of blood pressureGO:004577630.021
protein importGO:00170381300.020
immune system developmentGO:00025201950.020
behaviorGO:00076101120.020
inorganic ion transmembrane transportGO:00986602310.020
response to growth factorGO:00708482050.020
regulation of hormone levelsGO:00108171250.020
neuromuscular junction developmentGO:000752830.020
coagulationGO:0050817780.020
positive regulation of purine nucleotide metabolic processGO:19005442270.020
cardiac muscle cell contractionGO:008600340.020
response to steroid hormoneGO:0048545800.020
response to drugGO:0042493810.020
symbiosis encompassing mutualism through parasitismGO:00444031560.020
positive regulation of protein transportGO:00512221350.020
mitotic cell cycle processGO:19030472860.020
regulation of growthGO:00400081650.020
lipid catabolic processGO:0016042840.020
ameboidal type cell migrationGO:00016671350.020
regulation of apoptotic signaling pathwayGO:20012331750.020
single organism membrane organizationGO:00448022680.020
negative regulation of immune system processGO:00026831360.020
negative regulation of cell motilityGO:20001461040.020
regulation of cell activationGO:00508651250.020
positive regulation of locomotionGO:00400171860.020
response to oxidative stressGO:00069791210.020
Human
protein targeting to nucleusGO:00447441040.020
growthGO:00400072020.020
activation of immune responseGO:00022531140.020
carboxylic acid transportGO:0046942630.020
circadian behaviorGO:004851220.019
blastoderm segmentationGO:000735020.019
memoryGO:000761330.019
protein oligomerizationGO:00512591730.019
calcium ion homeostasisGO:00550741220.019
ribonucleoside monophosphate catabolic processGO:00091581580.019
limbic system developmentGO:002176130.019
mitotic cell cycle phase transitionGO:00447721620.019
protein import into nucleusGO:00066061040.019
adult locomotory behaviorGO:000834410.019
response to nutrient levelsGO:0031667810.019
myeloid cell differentiationGO:00300991170.019
coenzyme metabolic processGO:0006732650.019
reactive oxygen species biosynthetic processGO:190340940.019
actin mediated cell contractionGO:0070252120.019
gtp metabolic processGO:00460392390.018
cellular divalent inorganic cation homeostasisGO:00725031280.018
regulation of metal ion transportGO:00109591200.018
nucleoside monophosphate metabolic processGO:00091231910.018
response to activityGO:001482300.018
cellular protein complex assemblyGO:00436231880.018
regulation of body fluid levelsGO:0050878990.018
positive regulation of nucleotide metabolic processGO:00459812300.018
cellular response to lipidGO:00713961270.018
posttranscriptional regulation of gene expressionGO:00106082130.018
endocytosisGO:00068971590.018
purine ribonucleoside monophosphate catabolic processGO:00091691580.018
positive regulation of immune responseGO:00507781590.018
regulation of cytoplasmic transportGO:19036491490.018
cellular protein catabolic processGO:00442572610.018
divalent inorganic cation homeostasisGO:00725071360.018
generation of neuronsGO:00486991520.018
regulation of nucleoside metabolic processGO:00091182090.018
actin filament based movementGO:0030048170.018
positive regulation of cell adhesionGO:0045785840.018
matingGO:000761810.018
proteolysis involved in cellular protein catabolic processGO:00516032440.018
cell divisionGO:00513011680.018
leukocyte activationGO:00453211640.018
oocyte developmentGO:004859910.018
immune effector processGO:00022521590.018
regulation of reactive oxygen species biosynthetic processGO:190342630.018
regulation of neural precursor cell proliferationGO:200017740.017
regulation of protein serine threonine kinase activityGO:00719001790.017
anterior posterior axis specificationGO:000994820.017
regulation of purine nucleotide catabolic processGO:00331212050.017
spermatid differentiationGO:004851540.017
peptidyl lysine modificationGO:00182051440.017
associative learningGO:000830610.017
regulation of endopeptidase activityGO:00525481700.017
protein homooligomerizationGO:00512601000.017
regulation of cell cycle processGO:00105642660.017
protein localization to nucleusGO:00345041360.017
sequestering of metal ionGO:0051238240.017
regulation of protein maturationGO:19033171500.017
negative regulation of cellular component movementGO:00512711060.017
monocarboxylic acid biosynthetic processGO:0072330670.017
regulation of cell developmentGO:00602841610.017
reactive nitrogen species metabolic processGO:200105730.017
fatty acid biosynthetic processGO:0006633460.017
muscle system processGO:0003012810.017
modification dependent macromolecule catabolic processGO:00436322120.017
cell growthGO:00160491600.017
defense response to other organismGO:00985421290.017
negative regulation of cell cycleGO:00457861930.016
nucleoside monophosphate catabolic processGO:00091251590.016
actin cytoskeleton organizationGO:00300362070.016
organic acid transportGO:0015849650.016
atp catabolic processGO:00062001570.016
negative regulation of angiogenesisGO:0016525390.016
modification dependent protein catabolic processGO:00199412090.016
regulation of membrane potentialGO:0042391950.016
rna interferenceGO:001624640.016
tissue regenerationGO:004224630.016
inner ear morphogenesisGO:004247240.016
negative regulation of growthGO:0045926970.016
oocyte differentiationGO:000999420.016
spermatid developmentGO:000728640.016
response to peptideGO:1901652650.016
calcium ion transportGO:00068161470.016
divalent metal ion transportGO:00708381520.016
positive regulation of cytosolic calcium ion concentrationGO:0007204820.016
nucleotide biosynthetic processGO:00091651090.016
response to estrogenGO:0043627470.016
cell type specific apoptotic processGO:00972851250.016
multi organism cellular processGO:00447641560.016
cellular response to external stimulusGO:00714961110.016
post embryonic organ developmentGO:004856910.016
sequestering of calcium ionGO:0051208170.016
endomembrane system organizationGO:00102561960.016
response to hypoxiaGO:0001666960.016
Human
atp metabolic processGO:00460341760.015
regulation of protein modification by small protein conjugation or removalGO:19033201070.015
cytokine mediated signaling pathwayGO:00192211090.015
protein autophosphorylationGO:00467771230.015
response to alcoholGO:0097305640.015
negative regulation of transferase activityGO:00513481240.015
negative regulation of protein phosphorylationGO:00019331400.015
chemotaxisGO:00069351570.015
ubiquitin dependent protein catabolic processGO:00065112060.015
midgut developmentGO:000749410.015
regulation of epithelial cell proliferationGO:00506781130.015
phospholipid metabolic processGO:0006644990.015
regulation of stress activated protein kinase signaling cascadeGO:0070302850.015
interspecies interaction between organismsGO:00444191560.015
regulation of nucleotide catabolic processGO:00308112050.015
regulation of endothelial cell migrationGO:0010594670.015
positive regulation of reactive oxygen species biosynthetic processGO:190342820.015
lipid oxidationGO:0034440330.015
muscle contractionGO:0006936730.015
response to reactive oxygen speciesGO:0000302610.015
Human
regulation of gtp catabolic processGO:00331241800.015
regulation of peptidase activityGO:00525471800.015
regulation of transmembrane transportGO:00347621390.015
hexose metabolic processGO:0019318550.015
activation of protein kinase activityGO:0032147900.015
purine containing compound biosynthetic processGO:0072522880.015
purine nucleoside monophosphate catabolic processGO:00091281580.015
intracellular receptor signaling pathwayGO:00305221040.015
Human
cell matrix adhesionGO:0007160850.015
single organism nuclear importGO:19025931040.015
anion transmembrane transportGO:0098656760.015
protein secretionGO:0009306980.015
regulation of lipid metabolic processGO:0019216960.015
negative regulation of proteolysisGO:00458611320.015
microtubule based processGO:00070172100.015
cellular response to glucocorticoid stimulusGO:007138540.014
gtp catabolic processGO:00061842370.014
lipid transportGO:0006869900.014
glycoprotein metabolic processGO:00091001100.014
cellular response to reactive oxygen speciesGO:0034614500.014
Human
guanosine containing compound catabolic processGO:19010692390.014
wound healingGO:00420601150.014
organic hydroxy compound transportGO:0015850630.014
regulation of innate immune responseGO:0045088970.014
regulation of protein catabolic processGO:00421761550.014
positive regulation of cell cycleGO:00457871400.014
chromatin organizationGO:00063253510.014
positive regulation of gliogenesisGO:001401540.014
negative regulation of cytokine productionGO:0001818820.014
ribose phosphate biosynthetic processGO:0046390820.014
organ morphogenesisGO:00098871470.014
reproductive processGO:00224141060.014
negative regulation of protein processingGO:00109551420.014
thymus developmentGO:004853830.014
response to molecule of bacterial originGO:0002237820.014
regulation of cysteine type endopeptidase activityGO:20001161270.014
neuroblast proliferationGO:000740540.014
second messenger mediated signalingGO:0019932780.014
regulation of protein ubiquitinationGO:0031396950.014
cell cycle phase transitionGO:00447701730.014
regulation of ion homeostasisGO:2000021730.014
neural crest cell developmentGO:001403230.014
response to metal ionGO:0010038840.014
sensory perception of painGO:001923340.014
regulation of cell morphogenesisGO:00226041530.014
lung alveolus developmentGO:004828640.014
hemostasisGO:0007599760.014
stem cell divisionGO:001714520.014
regulation of glial cell differentiationGO:004568530.014
small molecule catabolic processGO:0044282920.014
regulation of dna metabolic processGO:00510521530.014
neuron differentiationGO:00301821380.014
defense response to bacteriumGO:0042742630.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
cellular calcium ion homeostasisGO:00068741170.014
regulation of protein secretionGO:0050708860.014
embryonic epithelial tube formationGO:000183840.014
extrinsic apoptotic signaling pathwayGO:00971911190.014
ossificationGO:00015031210.014
divalent inorganic cation transportGO:00725111580.014
response to low density lipoprotein particleGO:005509840.014
response to peptide hormoneGO:0043434610.014

PDK4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.066
inherited metabolic disorderDOID:6552420.044
musculoskeletal system diseaseDOID:172230.029
nervous system diseaseDOID:8634310.028
sensory system diseaseDOID:00501552030.028
cardiovascular system diseaseDOID:12871060.027
disease of cellular proliferationDOID:145661740.026
cancerDOID:1621670.026
eye and adnexa diseaseDOID:14921500.025
eye diseaseDOID:56141490.025
muscle tissue diseaseDOID:661130.023
muscular diseaseDOID:00800001140.023
myopathyDOID:4231040.023
central nervous system diseaseDOID:3311860.021
retinal diseaseDOID:56791180.020
organ system cancerDOID:00506861640.018
retinal degenerationDOID:8466890.015
immune system diseaseDOID:29141550.014