Homo sapiens

20 known processes

PIKFYVE

phosphoinositide kinase, FYVE finger containing

(Aliases: PIP5K3,PIP5K,FAB1,FLJ37746,MGC40423,CFD,KIAA0981)

PIKFYVE biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.138
glycerolipid metabolic processGO:00464861070.130
Yeast Mouse
phosphatidylinositol metabolic processGO:0046488530.118
Yeast Mouse
lipid metabolic processGO:00066293810.113
Yeast Mouse
regulation of cellular amino acid metabolic processGO:000652160.089
maintenance of locationGO:00512351120.075
amine metabolic processGO:0009308440.062
vesicle mediated transportGO:00161923710.062
regulation of transferase activityGO:00513383550.058
positive regulation of cellular amine metabolic processGO:003324070.058
cytoplasmic transportGO:00164823790.056
cellular ketone metabolic processGO:0042180800.055
regulation of cellular amine metabolic processGO:0033238110.055
oogenesisGO:004847720.053
phospholipid metabolic processGO:0006644990.053
Yeast Mouse
glycerolipid biosynthetic processGO:0045017510.053
positive regulation of transferase activityGO:00513472270.053
cellular lipid metabolic processGO:00442553030.051
Yeast Mouse
cellular macromolecular complex assemblyGO:00346223240.050
regulation of cellular ketone metabolic processGO:0010565500.050
small gtpase mediated signal transductionGO:0007264780.050
determination of adult lifespanGO:000834020.050
nervous system developmentGO:00073992930.047
Mouse
ras protein signal transductionGO:0007265730.046
organophosphate biosynthetic processGO:00904071630.041
cation transportGO:00068123310.041
chromatin organizationGO:00063253510.039
multicellular organismal agingGO:001025930.039
inner ear morphogenesisGO:004247240.039
regulation of kinase activityGO:00435493140.038
glycosyl compound catabolic processGO:19016584130.038
cellular protein complex assemblyGO:00436231880.036
positive regulation of kinase activityGO:00336742040.036
memoryGO:000761330.036
cellular amino acid metabolic processGO:00065201160.036
biological adhesionGO:00226103310.035
positive regulation of developmental processGO:00510943140.034
oocyte developmentGO:004859910.033
microtubule organizing center organizationGO:0031023620.033
transmembrane transportGO:00550853990.032
dephosphorylationGO:00163112090.032
lipid modificationGO:0030258840.031
Yeast Mouse
female gamete generationGO:000729220.031
oocyte differentiationGO:000999420.030
cellular amine metabolic processGO:0044106410.029
phosphatidylinositol biosynthetic processGO:0006661250.029
protein localization to organelleGO:00333652800.029
cell adhesionGO:00071553250.029
glycerophospholipid metabolic processGO:0006650840.029
Yeast Mouse
negative regulation of protein metabolic processGO:00512483910.028
carbohydrate metabolic processGO:00059752070.028
positive regulation of phosphorylationGO:00423273940.028
morphogenesis of embryonic epitheliumGO:001633140.027
chromatin modificationGO:00165682980.027
system processGO:00030083490.026
membrane organizationGO:00610242920.026
glycerophospholipid biosynthetic processGO:0046474400.026
covalent chromatin modificationGO:00165692540.026
phospholipid biosynthetic processGO:0008654440.026
mitotic cell cycleGO:00002783260.025
cellular response to dna damage stimulusGO:00069743790.025
establishment or maintenance of cytoskeleton polarityGO:003095230.025
metal ion transportGO:00300012720.024
negative regulation of cellular protein metabolic processGO:00322693530.024
single organism cellular localizationGO:19025803320.024
negative regulation of transportGO:00510511760.024
dna repairGO:00062811980.024
regulation of cellular component biogenesisGO:00440872810.024
positive regulation of protein phosphorylationGO:00019343130.023
regulation of cell differentiationGO:00455953930.023
neurological system processGO:00508771630.023
mitotic cell cycle processGO:19030472860.023
macromolecule methylationGO:0043414970.023
protein modification by small protein conjugationGO:00324463420.022
ribonucleoside triphosphate catabolic processGO:00092033910.022
inorganic ion transmembrane transportGO:00986602310.022
small molecule biosynthetic processGO:00442831570.022
neuromuscular junction developmentGO:000752830.022
nitrogen compound transportGO:00717051910.022
lipid localizationGO:00108761060.022
purine ribonucleoside triphosphate metabolic processGO:00092054110.022
negative regulation of programmed cell deathGO:00430693210.022
forelimb morphogenesisGO:003513640.022
organelle fissionGO:00482851490.022
embryonic epithelial tube formationGO:000183840.021
purine containing compound catabolic processGO:00725234110.021
microtubule based processGO:00070172100.021
reactive oxygen species metabolic processGO:0072593750.021
negative regulation of cell deathGO:00605483450.021
spinal cord developmentGO:002151040.021
carbohydrate derivative biosynthetic processGO:19011372070.021
negative regulation of apoptotic processGO:00430663160.021
neuron differentiationGO:00301821380.021
secretionGO:00469032540.021
purine ribonucleoside triphosphate catabolic processGO:00092073910.021
hindbrain developmentGO:003090230.021
purine nucleotide catabolic processGO:00061954050.021
positive regulation of nucleotide metabolic processGO:00459812300.020
nuclear divisionGO:00002801280.020
nucleotide catabolic processGO:00091664080.020
negative regulation of catalytic activityGO:00430863350.020
negative regulation of phosphate metabolic processGO:00459362670.020
cellular component morphogenesisGO:00329893140.020
Mouse
cation transmembrane transportGO:00986552380.020
metencephalon developmentGO:002203720.020
nucleoside catabolic processGO:00091644080.020
intracellular protein transportGO:00068862700.020
spermatid developmentGO:000728640.020
protein ubiquitinationGO:00165673140.020
response to oxygen containing compoundGO:19017003690.020
regulation of growthGO:00400081650.020
negative regulation of multicellular organismal processGO:00512413170.020
negative regulation of protein modification processGO:00314002000.019
negative regulation of phosphorus metabolic processGO:00105632670.019
purine ribonucleoside metabolic processGO:00461284370.019
response to other organismGO:00517072610.019
positive regulation of cellular amino acid metabolic processGO:004576430.019
reactive nitrogen species metabolic processGO:200105730.019
actin filament based processGO:00300292240.019
chemotaxisGO:00069351570.019
cell morphogenesisGO:00009022960.019
generation of neuronsGO:00486991520.019
oxidation reduction processGO:00551143960.018
growthGO:00400072020.018
rna processingGO:00063962550.018
regulation of cell cycleGO:00517263930.018
organelle assemblyGO:00709251760.018
spindle elongationGO:005123140.018
cell projection organizationGO:00300302520.018
endosomal transportGO:00161971290.018
nerve developmentGO:002167540.018
immune responseGO:00069553070.018
cerebellum developmentGO:002154920.017
regulation of ion transportGO:00432691890.017
response to growth factorGO:00708482050.017
positive regulation of purine nucleotide metabolic processGO:19005442270.017
morphogenesis of a polarized epitheliumGO:000173830.017
nucleoside triphosphate catabolic processGO:00091433940.017
purine ribonucleotide catabolic processGO:00091544040.017
positive regulation of phagocytosis engulfmentGO:006010010.017
inorganic cation transmembrane transportGO:00986621940.017
nucleoside triphosphate metabolic processGO:00091414220.017
negative regulation of intracellular signal transductionGO:19025321830.017
mapk cascadeGO:00001652880.017
ribonucleoside catabolic processGO:00424544060.017
establishment of tissue polarityGO:000716430.017
organonitrogen compound biosynthetic processGO:19015662000.017
reproductive processGO:00224141060.017
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.017
cell growthGO:00160491600.017
mitotic spindle elongationGO:000002240.017
regulation of phagocytosis engulfmentGO:006009920.017
regulation of establishment of protein localizationGO:00702012420.017
cellular response to abiotic stimulusGO:00712141170.017
regulation of anatomical structure morphogenesisGO:00226032860.017
positive regulation of cellular component organizationGO:00511303760.017
positive regulation of synaptic transmissionGO:005080640.017
microtubule cytoskeleton organizationGO:00002261760.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
rna interferenceGO:001624640.016
neuron developmentGO:00486661130.016
ribonucleoside triphosphate metabolic processGO:00091994120.016
positive regulation of hydrolase activityGO:00513453310.016
maintenance of protein locationGO:0045185570.016
cellular macromolecule catabolic processGO:00442653800.016
maintenance of protein location in cellGO:0032507560.016
regulation of nucleotide metabolic processGO:00061402690.016
establishment of planar polarityGO:000173630.016
regulation of ras protein signal transductionGO:00465781550.016
regulation of small gtpase mediated signal transductionGO:00510561560.016
response to abiotic stimulusGO:00096283360.016
wnt signaling pathwayGO:00160551560.016
regulation of cell cycle processGO:00105642660.016
response to biotic stimulusGO:00096072760.016
ossificationGO:00015031210.016
regulation of intracellular transportGO:00323861950.016
segmentationGO:003528240.016
guanosine containing compound catabolic processGO:19010692390.016
cellular chemical homeostasisGO:00550821800.015
response to external biotic stimulusGO:00432072610.015
cellular protein catabolic processGO:00442572610.015
canonical wnt signaling pathwayGO:00600701160.015
endocytosisGO:00068971590.015
purine ribonucleoside catabolic processGO:00461303980.015
regulation of protein kinase activityGO:00458592890.015
histone modificationGO:00165702510.015
regulation of wnt signaling pathwayGO:00301111230.015
peptidyl serine modificationGO:00182091060.015
mitochondrion organizationGO:00070051560.015
positive regulation of transportGO:00510503360.015
anatomical structure formation involved in morphogenesisGO:00486462840.015
Mouse
g protein coupled receptor signaling pathwayGO:00071862070.015
cellular response to organonitrogen compoundGO:00714171240.015
signal transduction by phosphorylationGO:00230142970.015
cell divisionGO:00513011680.015
protein targetingGO:00066051870.015
regulation of cytoskeleton organizationGO:00514931770.015
cell part morphogenesisGO:00329901370.015
positive regulation of immune system processGO:00026842830.015
positive regulation of organelle organizationGO:00106381950.014
protein complex disassemblyGO:0043241520.014
protein catabolic processGO:00301633250.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
response to axon injuryGO:004867810.014
establishment of protein localization to organelleGO:00725941720.014
negative regulation of cellular component organizationGO:00511292350.014
anion transportGO:00068201610.014
centrosome organizationGO:0051297580.014
cellular component disassemblyGO:0022411920.014
spindle stabilizationGO:004314640.014
mitotic nuclear divisionGO:00070671190.014
immune system developmentGO:00025201950.014
organophosphate catabolic processGO:00464344300.014
neuron projection developmentGO:00311751060.014
cytokine productionGO:00018162470.014
hair cell differentiationGO:003531520.013
nucleoside phosphate catabolic processGO:19012924120.013
regulation of peptidyl serine phosphorylationGO:0033135500.013
mitotic sister chromatid segregationGO:0000070530.013
lipid biosynthetic processGO:00086101770.013
myosin filament assemblyGO:003103420.013
nuclear transportGO:00511691790.013
retrograde transport endosome to golgiGO:0042147450.013
negative regulation of developmental processGO:00510932470.013
spermatid differentiationGO:004851540.013
male meiosisGO:000714010.013
regulation of dna metabolic processGO:00510521530.013
negative regulation of organelle organizationGO:00106391260.013
regulation of cell divisionGO:00513021160.013
circadian behaviorGO:004851220.013
locomotory behaviorGO:000762610.013
regulation of purine nucleotide catabolic processGO:00331212050.013
microtubule anchoringGO:0034453240.013
negative regulation of phosphorylationGO:00423261740.013
sister chromatid segregationGO:0000819540.013
symbiosis encompassing mutualism through parasitismGO:00444031560.013
regulation of multi organism processGO:00439001570.013
purine nucleoside triphosphate metabolic processGO:00091444120.013
regulation of mapk cascadeGO:00434082620.013
actin cytoskeleton organizationGO:00300362070.013
multi organism cellular processGO:00447641560.013
regulation of protein localizationGO:00328802960.013
posttranscriptional regulation of gene expressionGO:00106082130.013
leukocyte activationGO:00453211640.013
regulation of neural precursor cell proliferationGO:200017740.013
peptidyl lysine methylationGO:0018022370.013
ribonucleotide catabolic processGO:00092614050.013
taxisGO:00423301570.013
rho protein signal transductionGO:0007266260.013
single organism reproductive processGO:0044702980.013
atp catabolic processGO:00062001570.012
long term memoryGO:000761620.012
protein alkylationGO:0008213740.012
regulation of protein transportGO:00512232130.012
single organism carbohydrate metabolic processGO:00447231930.012
amide transportGO:0042886760.012
positive regulation of apoptotic processGO:00430652460.012
positive regulation of cell differentiationGO:00455972110.012
primary neural tube formationGO:001402030.012
atp metabolic processGO:00460341760.012
striated muscle myosin thick filament assemblyGO:007168820.012
chemical homeostasisGO:00488783060.012
maintenance of location in cellGO:0051651620.012
regulation of proteolysisGO:00301622930.012
regulation of vesicle mediated transportGO:00606271300.012
serotonin uptakeGO:005161020.012
positive regulation of nucleoside metabolic processGO:00459791860.012
adult locomotory behaviorGO:000834410.012
response to hormoneGO:00097251750.012
matingGO:000761810.012
peripheral nervous system developmentGO:000742220.012
neural tube formationGO:000184130.012
neural tube closureGO:000184330.012
embryo developmentGO:00097901230.012
cellular homeostasisGO:00197251960.012
tube closureGO:006060630.012
meiosis iGO:000712740.012
regulation of nucleoside metabolic processGO:00091182090.012
response to nitrogen compoundGO:19016981840.012
motor neuron axon guidanceGO:000804520.012
cardiovascular system developmentGO:00723582620.012
endomembrane system organizationGO:00102561960.012
protein localization to nucleusGO:00345041360.012
regulation of microtubule cytoskeleton organizationGO:0070507610.012
positive regulation of protein kinase activityGO:00458601900.012
cell activationGO:00017752130.012
regulation of secretionGO:00510461940.011
compound eye developmentGO:004874910.011
regulation of chromosome organizationGO:00330441030.011
innate immune responseGO:00450871780.011
purine nucleoside triphosphate catabolic processGO:00091463920.011
cellular response to growth factor stimulusGO:00713631970.011
organic anion transportGO:00157111030.011
regulation of meiotic cell cycleGO:005144540.011
purine nucleoside catabolic processGO:00061523980.011
cell projection morphogenesisGO:00488581290.011
regulation of meiosisGO:004002030.011
blastoderm segmentationGO:000735020.011
t cell differentiation in thymusGO:003307740.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
protein maturationGO:00516042330.011
enzyme linked receptor protein signaling pathwayGO:00071673030.011
mrna metabolic processGO:00160711750.011
glycosylationGO:0070085710.011
regulation of cytokine productionGO:00018172320.011
apoptotic signaling pathwayGO:00971902680.011
regulation of viral processGO:00507921030.011
chromosome segregationGO:00070591140.011
response to cytokineGO:00340972320.011
regulation of intracellular protein transportGO:00331571230.011
cellular response to epinephrine stimulusGO:007187220.011
skeletal system developmentGO:0001501790.011
regenerationGO:003109940.011
viral processGO:00160321460.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
protein dephosphorylationGO:0006470810.011
organic acid transportGO:0015849650.011
cell developmentGO:00484683280.011
regulation of protein complex assemblyGO:00432541470.011
interspecies interaction between organismsGO:00444191560.011
regulation of cellular response to stressGO:00801352440.011
nucleocytoplasmic transportGO:00069131760.011
response to fungusGO:000962040.011
negative regulation of synaptic transmissionGO:005080520.011
negative regulation of cytosolic calcium ion concentrationGO:005148110.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
neuroblast proliferationGO:000740540.011
embryonic camera type eye developmentGO:003107620.011
protein polymerizationGO:0051258710.011
tripartite regional subdivisionGO:000735120.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.011
cellular metal ion homeostasisGO:00068751460.011
positive regulation of nucleotide catabolic processGO:00308131850.011
intracellular receptor signaling pathwayGO:00305221040.011
blood vessel morphogenesisGO:00485141620.011
serotonin transportGO:000683730.011
embryonic eye morphogenesisGO:004804820.010
neurogenesisGO:00220081690.010
response to oxygen levelsGO:00704821000.010
embryonic placenta developmentGO:000189210.010
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.010
glycoprotein metabolic processGO:00091001100.010
cellular response to oxygen containing compoundGO:19017012760.010
hematopoietic or lymphoid organ developmentGO:00485341860.010
purine containing compound biosynthetic processGO:0072522880.010
regulation of canonical wnt signaling pathwayGO:0060828880.010
hemopoiesisGO:00300971800.010
guanosine containing compound metabolic processGO:19010682440.010
nucleoside phosphate biosynthetic processGO:19012931090.010
negative regulation of dephosphorylationGO:0035305630.010
regulation of apoptotic signaling pathwayGO:20012331750.010
nucleoside monophosphate metabolic processGO:00091231910.010
regulation of secretion by cellGO:19035301770.010

PIKFYVE disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
urinary system diseaseDOID:18400.021
nervous system diseaseDOID:8634310.019
central nervous system diseaseDOID:3311860.019
organ system cancerDOID:00506861640.016
cancerDOID:1621670.016
disease of cellular proliferationDOID:145661740.016
musculoskeletal system diseaseDOID:172230.014
muscular diseaseDOID:00800001140.014
sensory system diseaseDOID:00501552030.013
eye and adnexa diseaseDOID:14921500.010
eye diseaseDOID:56141490.010
muscle tissue diseaseDOID:661130.010