Homo sapiens

51 known processes

EIF5A

eukaryotic translation initiation factor 5A

(Aliases: MGC99547,EIF5A1,EIF-5A,eIF5AI,MGC104255)

EIF5A biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.116
determination of adult lifespanGO:000834020.058
Worm
nucleoside catabolic processGO:00091644080.055
cytoplasmic transportGO:00164823790.054
cellular amino acid metabolic processGO:00065201160.048
transmembrane transportGO:00550853990.046
ribonucleotide catabolic processGO:00092614050.046
amine metabolic processGO:0009308440.045
purine ribonucleoside triphosphate metabolic processGO:00092054110.043
cellular ketone metabolic processGO:0042180800.041
ribonucleoside catabolic processGO:00424544060.041
response to external biotic stimulusGO:00432072610.040
cation transportGO:00068123310.040
organophosphate catabolic processGO:00464344300.040
regulation of cellular amino acid metabolic processGO:000652160.039
negative regulation of protein metabolic processGO:00512483910.039
membrane organizationGO:00610242920.038
nucleotide catabolic processGO:00091664080.037
cellular macromolecule catabolic processGO:00442653800.037
secretionGO:00469032540.037
regulation of cellular ketone metabolic processGO:0010565500.036
rna processingGO:00063962550.035
purine ribonucleotide catabolic processGO:00091544040.035
nucleoside triphosphate catabolic processGO:00091433940.035
purine containing compound catabolic processGO:00725234110.034
regulation of cellular amine metabolic processGO:0033238110.034
purine nucleoside catabolic processGO:00061523980.034
multicellular organismal agingGO:001025930.034
Worm
nucleoside triphosphate metabolic processGO:00091414220.033
purine ribonucleoside triphosphate catabolic processGO:00092073910.033
negative regulation of catalytic activityGO:00430863350.032
single organism membrane organizationGO:00448022680.032
ribonucleoside triphosphate catabolic processGO:00092033910.032
intracellular protein transportGO:00068862700.032
positive regulation of hydrolase activityGO:00513453310.031
negative regulation of phosphorus metabolic processGO:00105632670.031
cellular amine metabolic processGO:0044106410.031
lipid metabolic processGO:00066293810.031
purine ribonucleoside catabolic processGO:00461303980.030
regenerationGO:003109940.030
nuclear transportGO:00511691790.030
purine nucleoside triphosphate metabolic processGO:00091444120.030
positive regulation of cellular amine metabolic processGO:003324070.030
cell morphogenesisGO:00009022960.029
cellular macromolecular complex assemblyGO:00346223240.029
protein localization to membraneGO:00726571600.029
regulation of transferase activityGO:00513383550.029
protein modification by small protein conjugationGO:00324463420.029
glycosyl compound catabolic processGO:19016584130.028
single organism cellular localizationGO:19025803320.028
nucleoside phosphate catabolic processGO:19012924120.028
nervous system developmentGO:00073992930.027
negative regulation of cellular amine metabolic processGO:003323930.027
regulation of purine nucleotide metabolic processGO:19005422640.027
oxidation reduction processGO:00551143960.026
protein maturationGO:00516042330.026
purine nucleotide catabolic processGO:00061954050.026
secretion by cellGO:00329402260.026
female gamete generationGO:000729220.026
actin filament based processGO:00300292240.026
positive regulation of cellular amino acid metabolic processGO:004576430.026
defense responseGO:00069523150.026
ion transmembrane transportGO:00342203380.026
ribonucleoside triphosphate metabolic processGO:00091994120.026
locomotory behaviorGO:000762610.025
response to other organismGO:00517072610.025
positive regulation of immune system processGO:00026842830.025
purine ribonucleoside metabolic processGO:00461284370.025
negative regulation of phosphate metabolic processGO:00459362670.025
negative regulation of cellular protein metabolic processGO:00322693530.025
apoptotic signaling pathwayGO:00971902680.025
cellular response to dna damage stimulusGO:00069743790.025
positive regulation of cellular catabolic processGO:00313312840.024
mitotic cell cycleGO:00002783260.024
proteolysis involved in cellular protein catabolic processGO:00516032440.024
negative regulation of cellular amino acid metabolic processGO:004576320.024
regulation of cell differentiationGO:00455953930.024
regulation of cell cycle processGO:00105642660.024
organonitrogen compound biosynthetic processGO:19015662000.023
positive regulation of cellular component organizationGO:00511303760.023
protein localization to organelleGO:00333652800.023
nucleocytoplasmic transportGO:00069131760.023
regulation of cell cycleGO:00517263930.023
establishment of protein localization to organelleGO:00725941720.023
mitochondrion organizationGO:00070051560.023
segmentationGO:003528240.023
regulation of cellular component movementGO:00512703340.023
negative regulation of smoothened signaling pathwayGO:004587930.022
response to abiotic stimulusGO:00096283360.022
cellular protein catabolic processGO:00442572610.022
regulation of cell motilityGO:20001452990.022
purine nucleoside triphosphate catabolic processGO:00091463920.022
biological adhesionGO:00226103310.022
small gtpase mediated signal transductionGO:0007264780.022
protein secretionGO:0009306980.021
oogenesisGO:004847720.021
cell projection organizationGO:00300302520.021
regulation of protein localizationGO:00328802960.021
protein catabolic processGO:00301633250.021
regulation of cell migrationGO:00303342890.021
posttranscriptional regulation of gene expressionGO:00106082130.021
spermatid differentiationGO:004851540.021
chemical homeostasisGO:00488783060.021
positive regulation of cell deathGO:00109422630.021
ras protein signal transductionGO:0007265730.021
nitrogen compound transportGO:00717051910.020
positive regulation of transferase activityGO:00513472270.020
immune responseGO:00069553070.020
response to biotic stimulusGO:00096072760.020
regulation of cellular component biogenesisGO:00440872810.020
regulation of proteolysisGO:00301622930.020
morphogenesis of embryonic epitheliumGO:001633140.020
positive regulation of phosphorylationGO:00423273940.020
multi organism cellular processGO:00447641560.020
positive regulation of catabolic processGO:00098963100.020
chromatin organizationGO:00063253510.020
mitotic cell cycle processGO:19030472860.019
enzyme linked receptor protein signaling pathwayGO:00071673030.019
generation of neuronsGO:00486991520.019
positive regulation of developmental processGO:00510943140.019
mitochondrial membrane organizationGO:0007006400.019
cation transmembrane transportGO:00986552380.019
negative regulation of cell deathGO:00605483450.019
regulation of nucleotide metabolic processGO:00061402690.019
regulation of response to external stimulusGO:00321012220.019
purine ribonucleoside monophosphate metabolic processGO:00091671860.019
guanosine containing compound catabolic processGO:19010692390.019
neuromuscular junction developmentGO:000752830.019
response to virusGO:00096151260.019
establishment of protein localization to membraneGO:00901501210.019
cellular component morphogenesisGO:00329893140.019
innate immune responseGO:00450871780.019
peripheral nervous system developmentGO:000742220.019
circulatory system developmentGO:00723592620.019
positive regulation of transportGO:00510503360.019
gtp metabolic processGO:00460392390.019
protein processingGO:00164852260.019
cellular chemical homeostasisGO:00550821800.018
small molecule biosynthetic processGO:00442831570.018
protein targetingGO:00066051870.018
positive regulation of nucleotide metabolic processGO:00459812300.018
negative regulation of protein modification processGO:00314002000.018
positive regulation of apoptotic processGO:00430652460.018
regulation of locomotionGO:00400123290.018
protein ubiquitinationGO:00165673140.018
cardiovascular system developmentGO:00723582620.018
symbiosis encompassing mutualism through parasitismGO:00444031560.018
anterior posterior axis specificationGO:000994820.017
regulation of nucleoside metabolic processGO:00091182090.017
response to axon injuryGO:004867810.017
guanosine containing compound metabolic processGO:19010682440.017
cellular homeostasisGO:00197251960.017
dephosphorylationGO:00163112090.017
cell part morphogenesisGO:00329901370.017
cellular response to oxidative stressGO:0034599850.017
regulation of cytokine productionGO:00018172320.017
regulation of anatomical structure morphogenesisGO:00226032860.017
modification dependent protein catabolic processGO:00199412090.017
positive regulation of programmed cell deathGO:00430682490.017
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.017
cell adhesionGO:00071553250.017
positive regulation of cell differentiationGO:00455972110.017
positive regulation of organelle organizationGO:00106381950.017
cellular response to oxygen containing compoundGO:19017012760.017
embryonic epithelial tube formationGO:000183840.017
cytokine productionGO:00018162470.017
chemotaxisGO:00069351570.017
metal ion transportGO:00300012720.017
regulation of cellular response to stressGO:00801352440.017
actin cytoskeleton organizationGO:00300362070.016
negative regulation of cellular component organizationGO:00511292350.016
negative regulation of apoptotic processGO:00430663160.016
maintenance of locationGO:00512351120.016
regulation of cytoskeleton organizationGO:00514931770.016
system processGO:00030083490.016
negative regulation of hydrolase activityGO:00513461820.016
organelle assemblyGO:00709251760.016
matingGO:000761810.016
modification dependent macromolecule catabolic processGO:00436322120.016
ribonucleoside monophosphate catabolic processGO:00091581580.016
lipid biosynthetic processGO:00086101770.016
regulation of protein transportGO:00512232130.016
regulation of nucleotide catabolic processGO:00308112050.016
motor neuron axon guidanceGO:000804520.016
cell growthGO:00160491600.016
cellular lipid metabolic processGO:00442553030.016
gtp catabolic processGO:00061842370.016
ncrna metabolic processGO:00346601080.016
regulation of kinase activityGO:00435493140.016
single organism carbohydrate metabolic processGO:00447231930.016
central nervous system developmentGO:00074171230.015
positive regulation of cellular component biogenesisGO:00440891580.015
limbic system developmentGO:002176130.015
negative regulation of multicellular organismal processGO:00512413170.015
neurogenesisGO:00220081690.015
ion homeostasisGO:00508012300.015
ubiquitin dependent protein catabolic processGO:00065112060.015
regulation of protein kinase activityGO:00458592890.015
anion transportGO:00068201610.015
regulation of protein processingGO:00706131500.015
negative regulation of intracellular signal transductionGO:19025321830.015
growthGO:00400072020.015
organophosphate biosynthetic processGO:00904071630.015
carbohydrate metabolic processGO:00059752070.015
oocyte differentiationGO:000999420.015
blastoderm segmentationGO:000735020.015
negative regulation of programmed cell deathGO:00430693210.015
microtubule based processGO:00070172100.015
oocyte developmentGO:004859910.015
spermatid developmentGO:000728640.015
syncytium formation by plasma membrane fusionGO:000076820.015
regulation of protein maturationGO:19033171500.015
response to oxygen containing compoundGO:19017003690.015
regulation of immune responseGO:00507762010.015
translationGO:00064121320.015
photoreceptor cell differentiationGO:004653020.014
vesicle mediated transportGO:00161923710.014
angiogenesisGO:00015251470.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
chromatin modificationGO:00165682980.014
response to woundingGO:00096111680.014
atp metabolic processGO:00460341760.014
positive regulation of synaptic transmissionGO:005080640.014
tripartite regional subdivisionGO:000735120.014
organic acid biosynthetic processGO:0016053970.014
cell morphogenesis involved in differentiationGO:00009041440.014
intrinsic apoptotic signaling pathwayGO:00971931270.014
intracellular protein transmembrane transportGO:0065002240.014
positive regulation of ras gtpase activityGO:00323201170.014
positive regulation of cell cycleGO:00457871400.014
proteasomal protein catabolic processGO:00104981760.014
viral life cycleGO:00190581320.014
nucleoside monophosphate catabolic processGO:00091251590.014
positive regulation of cell migrationGO:00303351720.014
negative regulation of organelle organizationGO:00106391260.014
defense response to other organismGO:00985421290.014
regulation of purine nucleotide catabolic processGO:00331212050.014
cellular protein complex assemblyGO:00436231880.014
signal transduction by phosphorylationGO:00230142970.014
regulation of endopeptidase activityGO:00525481700.014
taxisGO:00423301570.014
inorganic ion transmembrane transportGO:00986602310.014
protein oligomerizationGO:00512591730.014
rna splicingGO:00083801310.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.014
regulation of ion transportGO:00432691890.014
mitotic cell cycle phase transitionGO:00447721620.014
rna interferenceGO:001624640.014
interspecies interaction between organismsGO:00444191560.013
regulation of establishment of protein localizationGO:00702012420.013
cell projection morphogenesisGO:00488581290.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
reactive oxygen species biosynthetic processGO:190340940.013
cardiac muscle cell contractionGO:008600340.013
positive regulation of locomotionGO:00400171860.013
positive regulation of cell motilityGO:20001471770.013
cation homeostasisGO:00550801890.013
carboxylic acid biosynthetic processGO:0046394970.013
regulation of protein complex assemblyGO:00432541470.013
ribonucleoprotein complex biogenesisGO:00226131160.013
regulation of defense responseGO:00313471540.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
regulation of cell activationGO:00508651250.013
actin mediated cell contractionGO:0070252120.013
memoryGO:000761330.013
cell cycle checkpointGO:00000751170.013
regulation of cell adhesionGO:00301551660.013
monocarboxylic acid metabolic processGO:00327871850.013
carbohydrate derivative biosynthetic processGO:19011372070.013
establishment of planar polarityGO:000173630.013
regulation of ras gtpase activityGO:00323181280.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
regulation of intracellular transportGO:00323861950.013
microtubule cytoskeleton organizationGO:00002261760.013
anatomical structure formation involved in morphogenesisGO:00486462840.013
positive regulation of protein phosphorylationGO:00019343130.013
plasma membrane organizationGO:00070091150.013
tissue regenerationGO:004224630.012
regulation of multi organism processGO:00439001570.012
positive regulation of immune responseGO:00507781590.012
immune effector processGO:00022521590.012
dna catabolic processGO:0006308490.012
monocarboxylic acid biosynthetic processGO:0072330670.012
regulation of peptidase activityGO:00525471800.012
developmental programmed cell deathGO:001062330.012
response to metal ionGO:0010038840.012
regulation of cell developmentGO:00602841610.012
neural tube formationGO:000184130.012
adult locomotory behaviorGO:000834410.012
cell cycle phase transitionGO:00447701730.012
intracellular protein transmembrane importGO:0044743230.012
positive regulation of gtpase activityGO:00435471660.012
regulation of secretionGO:00510461940.012
response to nitrogen compoundGO:19016981840.012
positive regulation of gtp catabolic processGO:00331261660.012
osteoblast differentiationGO:0001649920.012
regulation of gtpase activityGO:00430871800.012
negative regulation of cell cycle processGO:00109481210.012
primary neural tube formationGO:001402030.012
negative regulation of phosphorylationGO:00423261740.012
response to fungusGO:000962040.012
regulation of bindingGO:00510981110.012
glycoprotein metabolic processGO:00091001100.012
dna repairGO:00062811980.012
glial cell migrationGO:000834740.012
mitotic nuclear divisionGO:00070671190.012
neuron differentiationGO:00301821380.012
negative regulation of cell cycleGO:00457861930.012
metal ion homeostasisGO:00550651690.012
organelle fissionGO:00482851490.012
rho protein signal transductionGO:0007266260.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
protein polyubiquitinationGO:00002091100.012
sequestering of metal ionGO:0051238240.012
regulation of apoptotic signaling pathwayGO:20012331750.012
epidermis morphogenesisGO:004873030.012
regulation of cell growthGO:00015581350.012
compound eye developmentGO:004874910.012
cellular metal ion homeostasisGO:00068751460.012
endosomal transportGO:00161971290.012
mrna processingGO:00063971330.012
inner ear morphogenesisGO:004247240.012
divalent metal ion transportGO:00708381520.012
anterior posterior axis specification embryoGO:000859520.012
embryo developmentGO:00097901230.012
Worm
regulation of secretion by cellGO:19035301770.012
organ formationGO:004864530.012
cerebellum developmentGO:002154920.012
cellular response to endogenous stimulusGO:00714953360.011
hindbrain developmentGO:003090230.011
negative regulation of cell proliferationGO:00082852280.011
negative regulation of protein processingGO:00109551420.011
covalent chromatin modificationGO:00165692540.011
organic hydroxy compound metabolic processGO:19016151470.011
cellular divalent inorganic cation homeostasisGO:00725031280.011
protein importGO:00170381300.011
organic anion transportGO:00157111030.011
t cell differentiation in thymusGO:003307740.011
blood vessel morphogenesisGO:00485141620.011
mrna metabolic processGO:00160711750.011
cell fate determinationGO:000170930.011
divalent inorganic cation homeostasisGO:00725071360.011
circadian behaviorGO:004851220.011
inorganic cation transmembrane transportGO:00986621940.011
endomembrane system organizationGO:00102561960.011
response to oxygen levelsGO:00704821000.011
i kappab kinase nf kappab signalingGO:00072491660.011
behaviorGO:00076101120.011
epithelial cell differentiationGO:00308551410.011
engulfment of apoptotic cellGO:004365220.011
blood vessel developmentGO:00015681720.011
histone modificationGO:00165702510.011
regulation of neural precursor cell proliferationGO:200017740.011
reactive nitrogen species metabolic processGO:200105730.011
cell projection assemblyGO:00300311260.011
myoblast fusionGO:000752010.011
metencephalon developmentGO:002203720.011
negative regulation of cellular catabolic processGO:0031330830.011
regulation of cell morphogenesisGO:00226041530.011
positive regulation of protein complex assemblyGO:0031334860.011
regulation of rna splicingGO:0043484620.011
vasculature developmentGO:00019441810.011
positive regulation of purine nucleotide catabolic processGO:00331231850.011
purine nucleoside monophosphate catabolic processGO:00091281580.011
monovalent inorganic cation transportGO:00156721280.011
response to bacteriumGO:00096171440.011
epithelium developmentGO:00604292270.011
regulation of gtp catabolic processGO:00331241800.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
divalent inorganic cation transportGO:00725111580.011
mapk cascadeGO:00001652880.011
positive regulation of cellular component movementGO:00512721810.011
positive regulation of response to external stimulusGO:0032103880.011
positive regulation of nucleoside metabolic processGO:00459791860.011
regulation of response to woundingGO:19030341010.011
cellular cation homeostasisGO:00300031630.011
viral processGO:00160321460.011
neurological system processGO:00508771630.011
positive regulation of mapk cascadeGO:00434101900.011
nerve developmentGO:002167540.011
cardiac muscle contractionGO:0060048340.011
rhythmic behaviorGO:000762220.011
regulation of protein stabilityGO:0031647870.011
response to lipidGO:00339932060.011
regulation of cytoplasmic transportGO:19036491490.011
positive regulation of cell cycle processGO:00900681060.011
alcohol metabolic processGO:00060661140.011
positive regulation of proteolysisGO:00458621420.011
cellular response to abiotic stimulusGO:00712141170.011
response to organic cyclic compoundGO:00140702040.011
lipid localizationGO:00108761060.011
neurotransmitter secretionGO:000726940.010
ossificationGO:00015031210.010
response to growth factorGO:00708482050.010
regulation of sequence specific dna binding transcription factor activityGO:00510902110.010
regulation of protein modification by small protein conjugation or removalGO:19033201070.010
regulation of transmembrane transportGO:00347621390.010
fatty acid metabolic processGO:00066311150.010
regulation of growthGO:00400081650.010
response to inorganic substanceGO:00100351270.010
tube closureGO:006060630.010
regulation of actin cytoskeleton organizationGO:00329561160.010
reactive oxygen species metabolic processGO:0072593750.010
establishment of protein localization to mitochondrionGO:0072655220.010
purine ribonucleotide biosynthetic processGO:0009152790.010
striated muscle myosin thick filament assemblyGO:007168820.010
neuroblast proliferationGO:000740540.010
negative regulation of cytokine productionGO:0001818820.010
response to cytokineGO:00340972320.010
cell activationGO:00017752130.010
single organism cell adhesionGO:00986021790.010
regulation of dna metabolic processGO:00510521530.010
spinal cord developmentGO:002151040.010
ribonucleoside monophosphate metabolic processGO:00091611870.010
atp catabolic processGO:00062001570.010
negative regulation of protein phosphorylationGO:00019331400.010
positive regulation of cytokine productionGO:00018191670.010
cell developmentGO:00484683280.010

EIF5A disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.023
central nervous system diseaseDOID:3311860.021
nervous system diseaseDOID:8634310.021
disease of metabolismDOID:00146672950.020
sensory system diseaseDOID:00501552030.019
cancerDOID:1621670.017
organ system cancerDOID:00506861640.017
disease of cellular proliferationDOID:145661740.017
immune system diseaseDOID:29141550.016
urinary system diseaseDOID:18400.014
connective tissue diseaseDOID:651090.014
bone diseaseDOID:0080001880.014
eye and adnexa diseaseDOID:14921500.014
eye diseaseDOID:56141490.013
neurodegenerative diseaseDOID:12891020.010
muscular diseaseDOID:00800001140.010
muscle tissue diseaseDOID:661130.010