Homo sapiens

45 known processes

MKNK2

MAP kinase interacting serine/threonine kinase 2

(Aliases: MNK2,GPRK7)

MKNK2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to nitrosative stressGO:005140940.261
cartilage condensationGO:000150210.238
response to salt stressGO:000965130.233
post embryonic developmentGO:000979120.202
cell aggregationGO:009874310.147
multicellular organismal agingGO:001025930.145
regulation of transferase activityGO:00513383550.141
cellular amine metabolic processGO:0044106410.126
negative regulation of catalytic activityGO:00430863350.123
signal transduction by phosphorylationGO:00230142970.118
regulation of kinase activityGO:00435493140.115
single organism carbohydrate metabolic processGO:00447231930.110
positive regulation of protein phosphorylationGO:00019343130.106
determination of adult lifespanGO:000834020.105
chromatin modificationGO:00165682980.101
posttranscriptional regulation of gene expressionGO:00106082130.095
carbohydrate metabolic processGO:00059752070.094
regulation of protein serine threonine kinase activityGO:00719001790.093
amine metabolic processGO:0009308440.084
cytokine productionGO:00018162470.082
ras protein signal transductionGO:0007265730.082
Fly
p38mapk cascadeGO:003806690.081
positive regulation of catabolic processGO:00098963100.081
response to abiotic stimulusGO:00096283360.080
lipid metabolic processGO:00066293810.079
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.078
covalent chromatin modificationGO:00165692540.078
regulation of protein kinase activityGO:00458592890.077
negative regulation of protein metabolic processGO:00512483910.077
dephosphorylationGO:00163112090.072
chromatin organizationGO:00063253510.072
regulation of cellular amino acid metabolic processGO:000652160.072
cellular ketone metabolic processGO:0042180800.069
cellular amino acid metabolic processGO:00065201160.068
regulation of sequence specific dna binding transcription factor activityGO:00510902110.068
response to oxygen containing compoundGO:19017003690.067
positive regulation of apoptotic processGO:00430652460.066
positive regulation of phosphorylationGO:00423273940.065
regulation of mapk cascadeGO:00434082620.065
response to biotic stimulusGO:00096072760.062
negative regulation of phosphorus metabolic processGO:00105632670.061
cellular macromolecule catabolic processGO:00442653800.059
regulation of cellular amine metabolic processGO:0033238110.056
positive regulation of cellular amine metabolic processGO:003324070.055
oxidation reduction processGO:00551143960.054
oogenesisGO:004847720.054
monocarboxylic acid metabolic processGO:00327871850.054
regulation of translationGO:0006417890.053
histone modificationGO:00165702510.053
regulation of cytokine productionGO:00018172320.052
cellular response to external stimulusGO:00714961110.052
cellular response to dna damage stimulusGO:00069743790.051
regulation of multi organism processGO:00439001570.051
rna stabilizationGO:0043489180.050
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.050
translationGO:00064121320.048
immune responseGO:00069553070.048
stress activated protein kinase signaling cascadeGO:0031098940.047
cellular response to oxygen containing compoundGO:19017012760.047
response to oxidative stressGO:00069791210.047
regulation of map kinase activityGO:00434051080.046
defense responseGO:00069523150.046
mapk cascadeGO:00001652880.046
protein autophosphorylationGO:00467771230.045
regulation of cellular ketone metabolic processGO:0010565500.045
innate immune responseGO:00450871780.045
positive regulation of programmed cell deathGO:00430682490.045
negative regulation of multicellular organismal processGO:00512413170.045
regulation of small gtpase mediated signal transductionGO:00510561560.045
Fly
positive regulation of protein kinase activityGO:00458601900.045
small gtpase mediated signal transductionGO:0007264780.045
Fly
cellular lipid metabolic processGO:00442553030.045
female gamete generationGO:000729220.045
growthGO:00400072020.045
Fly
peptidyl lysine modificationGO:00182051440.044
negative regulation of phosphate metabolic processGO:00459362670.044
cellular response to endogenous stimulusGO:00714953360.043
protein catabolic processGO:00301633250.043
regulation of mitotic cell cycleGO:00073461890.043
internal protein amino acid acetylationGO:00064751010.042
negative regulation of cell cycleGO:00457861930.042
negative regulation of cellular protein metabolic processGO:00322693530.041
positive regulation of cellular catabolic processGO:00313312840.041
regulation of innate immune responseGO:0045088970.041
response to external biotic stimulusGO:00432072610.040
stress activated mapk cascadeGO:0051403930.040
immune response regulating signaling pathwayGO:0002764970.040
system processGO:00030083490.039
response to cytokineGO:00340972320.039
protein localization to organelleGO:00333652800.038
regulation of response to external stimulusGO:00321012220.038
erk1 and erk2 cascadeGO:00703711040.038
positive regulation of transportGO:00510503360.037
negative regulation of developmental processGO:00510932470.037
nervous system developmentGO:00073992930.037
activation of immune responseGO:00022531140.037
positive regulation of cellular amino acid metabolic processGO:004576430.037
negative regulation of protein modification processGO:00314002000.036
mitotic cell cycleGO:00002783260.036
regulation of cellular response to stressGO:00801352440.035
innate immune response activating signal transductionGO:0002758480.035
positive regulation of cell proliferationGO:00082843010.035
response to other organismGO:00517072610.035
protein dephosphorylationGO:0006470810.035
negative regulation of protein phosphorylationGO:00019331400.034
response to inorganic substanceGO:00100351270.033
peptidyl serine modificationGO:00182091060.033
Human
hemopoiesisGO:00300971800.033
rho protein signal transductionGO:0007266260.033
hematopoietic or lymphoid organ developmentGO:00485341860.033
hyperosmotic responseGO:000697240.032
positive regulation of immune system processGO:00026842830.032
purine ribonucleotide catabolic processGO:00091544040.032
blastoderm segmentationGO:000735020.032
positive regulation of kinase activityGO:00336742040.032
positive regulation of mapk cascadeGO:00434101900.031
peptidyl lysine acetylationGO:00183941010.031
positive regulation of immune responseGO:00507781590.031
negative regulation of protein serine threonine kinase activityGO:0071901570.031
ribonucleotide catabolic processGO:00092614050.031
nucleoside triphosphate metabolic processGO:00091414220.031
positive regulation of cellular component organizationGO:00511303760.031
purine ribonucleoside metabolic processGO:00461284370.031
positive regulation of myoblast fusionGO:190174110.031
positive regulation of transferase activityGO:00513472270.031
glycosyl compound catabolic processGO:19016584130.030
regulation of cell differentiationGO:00455953930.030
proteolysis involved in cellular protein catabolic processGO:00516032440.030
oocyte differentiationGO:000999420.029
negative regulation of apoptotic processGO:00430663160.029
regulation of defense responseGO:00313471540.029
jnk cascadeGO:0007254800.029
purine ribonucleoside catabolic processGO:00461303980.029
regulation of erk1 and erk2 cascadeGO:0070372990.028
oocyte developmentGO:004859910.028
negative regulation of intracellular signal transductionGO:19025321830.028
Fly
jun phosphorylationGO:0007258280.028
defense response to other organismGO:00985421290.028
activation of protein kinase activityGO:0032147900.028
ribonucleoside triphosphate catabolic processGO:00092033910.028
cell adhesionGO:00071553250.028
positive regulation of defense responseGO:0031349870.028
locomotory behaviorGO:000762610.028
cardiovascular system developmentGO:00723582620.028
positive regulation of hydrolase activityGO:00513453310.027
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.027
defense response to gram positive bacteriumGO:0050830290.027
response to nitrogen compoundGO:19016981840.027
rna processingGO:00063962550.027
response to radiationGO:00093141510.026
response to uvGO:0009411730.026
regulation of chromosome organizationGO:00330441030.026
mitotic cell cycle processGO:19030472860.026
peptidyl tyrosine dephosphorylationGO:0035335360.026
response to peptideGO:1901652650.026
mrna metabolic processGO:00160711750.026
apoptotic signaling pathwayGO:00971902680.026
Mouse
single organism cellular localizationGO:19025803320.025
maintenance of locationGO:00512351120.025
positive regulation of cell deathGO:00109422630.025
rna interferenceGO:001624640.025
embryonic placenta developmentGO:000189210.025
response to growth factorGO:00708482050.025
negative regulation of erk1 and erk2 cascadeGO:0070373140.025
immune system developmentGO:00025201950.025
response to mechanical stimulusGO:0009612510.024
negative regulation of cell differentiationGO:00455961710.024
histone acetylationGO:0016573930.024
regulation of cell cycle processGO:00105642660.024
regenerationGO:003109940.024
response to organonitrogen compoundGO:00102431560.024
cellular response to nitrogen compoundGO:19016991440.024
monosaccharide metabolic processGO:0005996740.024
tissue regenerationGO:004224630.024
cellular response to hormone stimulusGO:00328701250.023
response to molecule of bacterial originGO:0002237820.023
regulation of immune responseGO:00507762010.023
t cell differentiation in thymusGO:003307740.023
response to fungusGO:000962040.023
response to lipidGO:00339932060.023
ribonucleoside triphosphate metabolic processGO:00091994120.023
mrna processingGO:00063971330.023
cell activationGO:00017752130.023
internal peptidyl lysine acetylationGO:0018393970.022
negative regulation of transferase activityGO:00513481240.022
peptidyl serine phosphorylationGO:00181051010.022
Human
cellular protein catabolic processGO:00442572610.022
segmentationGO:003528240.022
negative regulation of cell deathGO:00605483450.022
activation of mapk activityGO:0000187450.022
lymphocyte activationGO:00466491330.022
generation of neuronsGO:00486991520.022
response to light stimulusGO:0009416870.022
defense response to fungusGO:005083240.021
modification dependent protein catabolic processGO:00199412090.021
fatty acid metabolic processGO:00066311150.021
cytoplasmic transportGO:00164823790.021
cellular response to lipidGO:00713961270.021
purine nucleoside triphosphate metabolic processGO:00091444120.021
positive regulation of developmental processGO:00510943140.021
protein maturationGO:00516042330.021
negative regulation of cell proliferationGO:00082852280.021
circulatory system developmentGO:00723592620.021
tumor necrosis factor superfamily cytokine productionGO:0071706450.021
response to bacteriumGO:00096171440.021
meiotic chromosome segregationGO:004513240.021
protein localization to nucleusGO:00345041360.021
regulation of neural precursor cell proliferationGO:200017740.020
autophagyGO:0006914880.020
protein ubiquitinationGO:00165673140.020
endomembrane system organizationGO:00102561960.020
myoblast fusionGO:000752010.020
positive regulation of cell differentiationGO:00455972110.020
neuroblast proliferationGO:000740540.020
regulation of meiotic cell cycleGO:005144540.020
nuclear transportGO:00511691790.020
anterior posterior axis specification embryoGO:000859520.020
lipid localizationGO:00108761060.020
regulation of protein localizationGO:00328802960.020
immune response activating signal transductionGO:0002757900.020
purine nucleotide catabolic processGO:00061954050.020
response to extracellular stimulusGO:0009991850.020
anterior posterior axis specificationGO:000994820.020
positive regulation of cell sizeGO:004579330.020
negative regulation of programmed cell deathGO:00430693210.020
response to starvationGO:0042594590.019
hexose metabolic processGO:0019318550.019
protein acetylationGO:00064731160.019
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.019
biological adhesionGO:00226103310.019
protein acylationGO:00435431380.019
negative regulation of protein kinase activityGO:0006469980.019
negative regulation of phosphorylationGO:00423261740.019
cellular response to abiotic stimulusGO:00712141170.019
microtubule based processGO:00070172100.019
Fly
regulation of stress activated mapk cascadeGO:0032872840.019
cell developmentGO:00484683280.019
inactivation of mapk activityGO:000018850.019
enzyme linked receptor protein signaling pathwayGO:00071673030.019
purine ribonucleoside triphosphate catabolic processGO:00092073910.019
behavioral response to ethanolGO:004814920.019
regulation of cellular component sizeGO:0032535820.018
guanosine containing compound metabolic processGO:19010682440.018
activation of innate immune responseGO:0002218550.018
establishment of protein localization to organelleGO:00725941720.018
compound eye developmentGO:004874910.018
long chain fatty acid metabolic processGO:0001676300.018
sensory perception of painGO:001923340.018
chemical homeostasisGO:00488783060.018
tripartite regional subdivisionGO:000735120.018
photoreceptor cell differentiationGO:004653020.018
purine nucleoside catabolic processGO:00061523980.018
cell morphogenesisGO:00009022960.018
mrna destabilizationGO:006115710.018
response to osmotic stressGO:0006970170.018
ribonucleoside catabolic processGO:00424544060.018
cellular carbohydrate metabolic processGO:0044262840.018
negative regulation of hydrolase activityGO:00513461820.018
regulation of ras gtpase activityGO:00323181280.017
neurological system processGO:00508771630.017
midgut developmentGO:000749410.017
behaviorGO:00076101120.017
leukocyte differentiationGO:0002521980.017
regulation of cell cycleGO:00517263930.017
regulation of rho protein signal transductionGO:0035023790.017
embryo developmentGO:00097901230.017
memoryGO:000761330.017
histone serine phosphorylationGO:003540440.017
positive regulation of protein serine threonine kinase activityGO:00719021190.017
positive regulation of map kinase activityGO:0043406800.017
protein modification by small protein conjugationGO:00324463420.017
neurogenesisGO:00220081690.017
negative regulation of protein processingGO:00109551420.017
cell cycle phase transitionGO:00447701730.017
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.017
peptidyl tyrosine phosphorylationGO:00181081700.017
g1 s transition of mitotic cell cycleGO:0000082780.017
positive regulation of innate immune responseGO:0045089790.017
secretionGO:00469032540.017
myeloid cell differentiationGO:00300991170.017
positive regulation of nucleotide metabolic processGO:00459812300.017
ubiquitin dependent protein catabolic processGO:00065112060.017
regulation of anatomical structure sizeGO:00900661010.017
nucleotide catabolic processGO:00091664080.017
regulation of anatomical structure morphogenesisGO:00226032860.017
anion transportGO:00068201610.016
purine ribonucleoside triphosphate metabolic processGO:00092054110.016
positive regulation of purine nucleotide catabolic processGO:00331231850.016
cellular component morphogenesisGO:00329893140.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
response to nutrient levelsGO:0031667810.016
tumor necrosis factor productionGO:0032640430.016
cellular response to starvationGO:0009267580.016
single organism cell adhesionGO:00986021790.016
positive regulation of neural precursor cell proliferationGO:200017920.016
gtp metabolic processGO:00460392390.016
regulation of secretionGO:00510461940.016
cell cycle g1 s phase transitionGO:0044843800.016
negative regulation of catabolic processGO:00098951040.016
proteasomal protein catabolic processGO:00104981760.016
organ morphogenesisGO:00098871470.016
regulation of ras protein signal transductionGO:00465781550.016
Fly
regulation of proteolysisGO:00301622930.016
response to lipopolysaccharideGO:0032496700.016
nucleocytoplasmic transportGO:00069131760.016
secretion by cellGO:00329402260.016
positive regulation of organelle organizationGO:00106381950.016
regulation of syncytium formation by plasma membrane fusionGO:006014220.016
regulation of protein catabolic processGO:00421761550.016
vasculature developmentGO:00019441810.016
regulation of autophagyGO:0010506520.016
cell cycle checkpointGO:00000751170.016
organ formationGO:004864530.015
negative regulation of response to external stimulusGO:0032102830.015
nucleoside catabolic processGO:00091644080.015
regulation of bindingGO:00510981110.015
syncytium formation by plasma membrane fusionGO:000076820.015
regulation of cell growthGO:00015581350.015
cell junction maintenanceGO:003433140.015
spermatid differentiationGO:004851540.015
response to hormoneGO:00097251750.015
organophosphate biosynthetic processGO:00904071630.015
neuromuscular junction developmentGO:000752830.015
blood vessel morphogenesisGO:00485141620.015
inflammatory responseGO:0006954790.015
viral life cycleGO:00190581320.015
defense response to bacteriumGO:0042742630.015
endochondral bone morphogenesisGO:006035030.015
response to muramyl dipeptideGO:003249540.015
associative learningGO:000830610.015
cellular response to mechanical stimulusGO:0071260390.015
organic anion transportGO:00157111030.015
regulation of response to woundingGO:19030341010.015
regulation of growthGO:00400081650.015
Fly
lipid biosynthetic processGO:00086101770.015
regulation of jnk cascadeGO:0046328730.015
nuclear importGO:00511701060.015
lipid oxidationGO:0034440330.015
i kappab kinase nf kappab signalingGO:00072491660.015
tor signalingGO:0031929390.014
organonitrogen compound biosynthetic processGO:19015662000.014
positive regulation of myoblast differentiationGO:004566360.014
regulation of cell developmentGO:00602841610.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
wnt signaling pathwayGO:00160551560.014
heart developmentGO:0007507950.014
negative regulation of kinase activityGO:00336731060.014
negative regulation of proteolysisGO:00458611320.014
cellular homeostasisGO:00197251960.014
regulation of purine nucleotide catabolic processGO:00331212050.014
negative regulation of smoothened signaling pathwayGO:004587930.014
regulation of i kappab kinase nf kappab signalingGO:00431221620.014
positive regulation of nucleotide catabolic processGO:00308131850.014
striated muscle cell differentiationGO:0051146430.014
regulation of purine nucleotide metabolic processGO:19005422640.014
small molecule catabolic processGO:0044282920.014
peptidyl tyrosine modificationGO:00182121700.014
regulation of peptidase activityGO:00525471800.014
nuclear divisionGO:00002801280.014
hindbrain developmentGO:003090230.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
regulation of endopeptidase activityGO:00525481700.014
negative regulation of multi organism processGO:0043901920.014
nucleoside phosphate catabolic processGO:19012924120.014
demethylationGO:0070988370.014
positive regulation of gtp catabolic processGO:00331261660.014
oocyte maturationGO:000155610.014
epithelium developmentGO:00604292270.014
negative regulation of gliogenesisGO:001401430.014
purine containing compound catabolic processGO:00725234110.014
membrane organizationGO:00610242920.014
signal transduction by p53 class mediatorGO:0072331720.014
single organism membrane organizationGO:00448022680.014
cellular response to extracellular stimulusGO:0031668720.014
neurotransmitter secretionGO:000726940.014
sensory perception of smellGO:000760820.013
lung alveolus developmentGO:004828640.013
cell fate determinationGO:000170930.013
methylationGO:00322591060.013
epithelial cell differentiationGO:00308551410.013
regulation of behaviorGO:0050795820.013
reactive oxygen species biosynthetic processGO:190340940.013
regulation of protein processingGO:00706131500.013
atp metabolic processGO:00460341760.013
glucose metabolic processGO:0006006450.013
mitotic cell cycle phase transitionGO:00447721620.013
mrna stabilizationGO:0048255180.013
cardiac muscle contractionGO:0060048340.013
organophosphate catabolic processGO:00464344300.013
vesicle mediated transportGO:00161923710.013
extrinsic apoptotic signaling pathwayGO:00971911190.013
Mouse
regulation of wnt signaling pathwayGO:00301111230.013
nucleoside triphosphate catabolic processGO:00091433940.013
gtp catabolic processGO:00061842370.013
ion transmembrane transportGO:00342203380.013
cellular response to arsenic containing substanceGO:007124340.013
dna damage checkpointGO:0000077680.013
regulation of nucleoside metabolic processGO:00091182090.013
pattern recognition receptor signaling pathwayGO:0002221480.013
macromolecular complex disassemblyGO:0032984600.013
single organismal cell cell adhesionGO:00163371480.013
multi organism cellular processGO:00447641560.013
positive regulation of nucleoside metabolic processGO:00459791860.013
regulation of locomotionGO:00400123290.013
regulation of cellular component movementGO:00512703340.013
cellular response to growth factor stimulusGO:00713631970.013
myeloid leukocyte differentiationGO:0002573600.013
regulation of synaptic plasticityGO:004816730.013
intracellular protein transportGO:00068862700.013
limbic system developmentGO:002176130.013
morphogenesis of a polarized epitheliumGO:000173830.012
purine nucleoside triphosphate catabolic processGO:00091463920.012
interspecies interaction between organismsGO:00444191560.012
regulation of protein maturationGO:19033171500.012
neuron projection regenerationGO:003110210.012
reactive oxygen species metabolic processGO:0072593750.012
transmembrane transportGO:00550853990.012
muscle contractionGO:0006936730.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
3 utr mediated mrna stabilizationGO:007093580.012
regulation of protein bindingGO:0043393660.012
macroautophagyGO:0016236390.012
protein processingGO:00164852260.012
nitrogen compound transportGO:00717051910.012
positive regulation of nitric oxide synthase biosynthetic processGO:005177030.012
regulation of nervous system developmentGO:0051960880.012
anatomical structure homeostasisGO:00602491000.012
startle responseGO:000196430.012
negative regulation of mapk cascadeGO:0043409560.012
lipid modificationGO:0030258840.012
positive regulation of gtpase activityGO:00435471660.012
lipopolysaccharide mediated signaling pathwayGO:0031663260.012
regulation of nucleotide metabolic processGO:00061402690.012
heart formationGO:006091420.012
reactive nitrogen species metabolic processGO:200105730.012
striated muscle contractionGO:0006941520.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
defense response to gram negative bacteriumGO:0050829140.012
negative regulation of cellular amine metabolic processGO:003323930.012
regulation of gtpase activityGO:00430871800.012
reproductive processGO:00224141060.012
protein targeting to nucleusGO:00447441040.012
spermatid developmentGO:000728640.012
regulation of antimicrobial humoral responseGO:000275910.012
protein demethylationGO:0006482170.012
protein alkylationGO:0008213740.012
regulation of rho gtpase activityGO:0032319660.012
regulation of histone modificationGO:0031056470.012
morphogenesis of embryonic epitheliumGO:001633140.012
rna destabilizationGO:005077910.012
retinal ganglion cell axon guidanceGO:003129020.012
negative regulation of cellular component organizationGO:00511292350.012
positive regulation of meiotic cell cycleGO:005144620.012
mrna 3 end processingGO:0031124240.012
regulation of rna stabilityGO:0043487230.012
small molecule biosynthetic processGO:00442831570.012
muscle system processGO:0003012810.011
single organism reproductive processGO:0044702980.011
positive regulation of multi organism processGO:0043902560.011
regulation of carbohydrate metabolic processGO:0006109540.011
endocytosisGO:00068971590.011
generation of precursor metabolites and energyGO:0006091680.011
negative regulation of cell cycle processGO:00109481210.011
guanosine containing compound catabolic processGO:19010692390.011
negative regulation of locomotionGO:00400131180.011
regulation of dna metabolic processGO:00510521530.011
actin filament based processGO:00300292240.011
paracrine signalingGO:003800110.011
positive regulation of organic acid transportGO:003289230.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
rna catabolic processGO:0006401710.011
regulation of endothelial cell differentiationGO:004560140.011
tube closureGO:006060630.011
positive regulation of cytokine productionGO:00018191670.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
translational initiationGO:0006413480.011
rhythmic behaviorGO:000762220.011
positive regulation of syncytium formation by plasma membrane fusionGO:006014320.011
positive regulation of protein transportGO:00512221350.011
alcohol metabolic processGO:00060661140.011

MKNK2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.022
cancerDOID:1621670.018
organ system cancerDOID:00506861640.018
disease of cellular proliferationDOID:145661740.018
inherited metabolic disorderDOID:6552420.016
disease of metabolismDOID:00146672950.016
sensory system diseaseDOID:00501552030.015
nervous system diseaseDOID:8634310.015
muscle tissue diseaseDOID:661130.015
muscular diseaseDOID:00800001140.015
myopathyDOID:4231040.012
central nervous system diseaseDOID:3311860.012
connective tissue diseaseDOID:651090.012