Homo sapiens

217 known processes

LRP6

low density lipoprotein receptor-related protein 6

(Aliases: ADCAD2,FLJ90062,FLJ90421)

LRP6 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
canonical wnt signaling pathway involved in cardiac muscle cell fate commitmentGO:006131731.000
specification of organ identityGO:001009230.997
regulation of heart induction by regulation of canonical wnt signaling pathwayGO:009008110.986
negative regulation of cell fate commitmentGO:001045430.981
regulation of heart inductionGO:009038120.981
heart field specificationGO:000312820.978
heart formationGO:006091420.975
dermatome developmentGO:006105430.975
canonical wnt signaling pathwayGO:00600701160.974
positive regulation of canonical wnt signaling pathwayGO:0090263330.973
regulation of dermatome developmentGO:006118330.973
wnt signaling pathway calcium modulating pathwayGO:000722320.961
somitogenesisGO:000175620.946
Mouse
positive regulation of wnt signaling pathwayGO:0030177540.945
mesodermal cell fate commitmentGO:000171020.941
mesodermal cell fate specificationGO:000750120.938
negative regulation of wnt signaling pathwayGO:0030178690.938
Human Mouse
regulation of cellular amine metabolic processGO:0033238110.914
regulation of heart morphogenesisGO:200082640.910
Mouse
forebrain generation of neuronsGO:002187230.909
Mouse
heart inductionGO:000312940.905
cellular ketone metabolic processGO:0042180800.883
regulation of receptor mediated endocytosisGO:0048259320.856
regulation of cardiac muscle tissue developmentGO:0055024130.839
Mouse
receptor internalizationGO:0031623430.833
canonical wnt signaling pathway involved in heart developmentGO:006131630.831
Mouse
organ morphogenesisGO:00098871470.821
Human Mouse Fly
cardiac muscle cell fate commitmentGO:006092340.819
regulation of synaptic vesicle exocytosisGO:200030020.796
regulation of pathway restricted smad protein phosphorylationGO:0060393340.787
positive regulation of dermatome developmentGO:006118430.787
forebrain regionalizationGO:002187130.779
regulation of cellular amino acid metabolic processGO:000652160.771
cardiac muscle tissue developmentGO:0048738390.770
Mouse
regulation of receptor internalizationGO:0002090150.770
circulatory system developmentGO:00723592620.740
Human Mouse
negative regulation of canonical wnt signaling pathwayGO:0090090550.719
Human
positive regulation of map kinase activityGO:0043406800.712
Human
regulation of cell differentiationGO:00455953930.710
Human Mouse
regulation of organ formationGO:000315640.697
endodermal cell fate commitmentGO:000171140.690
regulation of anatomical structure morphogenesisGO:00226032860.687
Mouse
positive regulation of developmental processGO:00510943140.677
positive regulation of protein phosphorylationGO:00019343130.662
Human
wnt signaling pathwayGO:00160551560.657
segmentationGO:003528240.638
Mouse
gastrulationGO:0007369510.627
Mouse
formation of primary germ layerGO:0001704420.625
negative regulation of bmp signaling pathwayGO:0030514170.622
non canonical wnt signaling pathwayGO:0035567140.599
Mouse
cellular amine metabolic processGO:0044106410.593
positive regulation of cell fate commitmentGO:001045520.584
regulation of canonical wnt signaling pathwayGO:0060828880.583
regulation of synaptic vesicle transportGO:190280330.571
activation of mapk activityGO:0000187450.568
epithelium developmentGO:00604292270.567
Mouse
muscle cell fate commitmentGO:004269340.565
positive regulation of mapk cascadeGO:00434101900.559
Human
cell developmentGO:00484683280.553
canonical wnt signaling pathway involved in negative regulation of apoptotic processGO:004433620.549
negative regulation of cell differentiationGO:00455961710.549
Human Mouse
regulation of protein serine threonine kinase activityGO:00719001790.548
tube developmentGO:00352951250.548
Mouse
bmp signaling pathwayGO:0030509490.545
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.545
organ formationGO:004864530.544
organ inductionGO:000175940.532
peptidyl serine phosphorylationGO:00181051010.531
cellular amino acid metabolic processGO:00065201160.511
cell morphogenesis involved in differentiationGO:00009041440.502
negative regulation of cell fate specificationGO:000999630.500
regulation of intracellular transportGO:00323861950.490
Human
amine metabolic processGO:0009308440.488
regulation of mesoderm developmentGO:200038040.471
regulation of cellular component biogenesisGO:00440872810.458
cell fate commitment involved in formation of primary germ layerGO:006079560.455
negative regulation of mesenchymal cell proliferationGO:007220130.453
regulation of mesodermal cell fate specificationGO:004266120.453
positive regulation of phosphorylationGO:00423273940.452
Human
non canonical wnt signaling pathway via mapk cascadeGO:003803040.447
positive regulation of aldosterone metabolic processGO:003234620.436
mapk cascadeGO:00001652880.434
Human
positive regulation of cell differentiationGO:00455972110.434
Human
tissue morphogenesisGO:0048729960.429
Human Mouse
negative regulation of cellular component organizationGO:00511292350.427
negative regulation of phosphate metabolic processGO:00459362670.423
nervous system developmentGO:00073992930.423
Mouse Fly
regulation of cardiac muscle cell differentiationGO:200072570.420
enzyme linked receptor protein signaling pathwayGO:00071673030.418
Human
cardiovascular system developmentGO:00723582620.417
Human Mouse
negative regulation of cardiac muscle cell differentiationGO:200072630.414
cell morphogenesisGO:00009022960.412
negative regulation of gastrulationGO:200054240.405
regulation of kidney sizeGO:003556420.400
stem cell developmentGO:0048864690.399
regulation of neurotransmitter secretionGO:004692830.396
regulation of cellular ketone metabolic processGO:0010565500.392
regulation of locomotionGO:00400123290.386
response to oxygen containing compoundGO:19017003690.373
positive regulation of cell fate specificationGO:004266020.369
regulation of striated muscle tissue developmentGO:0016202260.368
Mouse
regulation of bmp signaling pathwayGO:0030510270.367
negative regulation of developmental processGO:00510932470.367
Human Mouse
cardiocyte differentiationGO:0035051230.367
Mouse
regulation of vesicle mediated transportGO:00606271300.366
negative regulation of phosphorus metabolic processGO:00105632670.362
neurotransmitter secretionGO:000726940.361
cellular component morphogenesisGO:00329893140.361
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.361
endodermal cell fate specificationGO:000171440.360
regulation of transferase activityGO:00513383550.355
intracellular protein transportGO:00068862700.349
Human Fly
regulation of wnt signaling pathwayGO:00301111230.348
regulation of cytoplasmic transportGO:19036491490.347
Human
receptor metabolic processGO:0043112810.347
single organism cellular localizationGO:19025803320.345
Human Fly
regulation of secretionGO:00510461940.345
Human
regulation of peroxidase activityGO:200046820.342
regulation of protein bindingGO:0043393660.340
muscle tissue developmentGO:0060537620.340
Mouse
digestive tract developmentGO:0048565750.340
Mouse
neural tube patterningGO:002153220.338
Mouse
cell differentiation in spinal cordGO:002151510.336
regulation of protein localizationGO:00328802960.336
Human
cell substrate adhesionGO:00315891320.328
regulation of intracellular protein transportGO:00331571230.319
Human
pathway restricted smad protein phosphorylationGO:0060389380.316
positive regulation of transportGO:00510503360.315
Human
anatomical structure formation involved in morphogenesisGO:00486462840.315
Human Mouse
regulation of protein kinase activityGO:00458592890.308
regulation of mapk cascadeGO:00434082620.304
Human
regulation of protein localization to nucleusGO:1900180850.304
Human
regulation of cell fate commitmentGO:001045370.303
mesenchymal cell differentiationGO:0048762520.300
digestive tract morphogenesisGO:0048546560.297
Mouse
protein targetingGO:00066051870.295
Human Fly
gtp catabolic processGO:00061842370.295
regulation of protein targetingGO:1903533910.295
Human
right ventricular cardiac muscle tissue morphogenesisGO:000322120.294
regulation of axon guidanceGO:190266730.290
regulation of kinase activityGO:00435493140.289
regulation of endocytosisGO:0030100720.284
cellular response to endogenous stimulusGO:00714953360.284
regulation of purine nucleotide catabolic processGO:00331212050.284
regulation of nucleotide metabolic processGO:00061402690.281
taxisGO:00423301570.280
cellular macromolecular complex assemblyGO:00346223240.280
positive regulation of nucleotide metabolic processGO:00459812300.277
secretionGO:00469032540.276
Human
positive regulation of stress activated mapk cascadeGO:0032874600.275
cell adhesionGO:00071553250.273
Rat
protein import into nucleusGO:00066061040.269
Human
positive regulation of protein serine threonine kinase activityGO:00719021190.265
Human
protein localization to organelleGO:00333652800.264
Human Fly
negative regulation of cellular amino acid metabolic processGO:004576320.263
purine nucleotide catabolic processGO:00061954050.258
positive regulation of cellular component organizationGO:00511303760.257
Human
regulation of neural precursor cell proliferationGO:200017740.250
heart developmentGO:0007507950.248
Mouse
regulation of cell developmentGO:00602841610.247
Mouse
purine nucleoside triphosphate metabolic processGO:00091444120.243
regulation of wnt signaling pathway involved in heart developmentGO:000330730.242
Mouse
negative regulation of phosphorylationGO:00423261740.241
mesoderm formationGO:0001707100.237
spinal cord developmentGO:002151040.237
establishment of protein localization to organelleGO:00725941720.235
Human Fly
regulation of cell morphogenesis involved in differentiationGO:0010769830.233
tube morphogenesisGO:0035239950.232
Mouse
striated muscle tissue developmentGO:0014706590.230
Mouse
morphogenesis of a polarized epitheliumGO:000173830.230
neuron differentiationGO:00301821380.228
Mouse
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.226
positive regulation of nucleotide catabolic processGO:00308131850.223
regulation of cell migrationGO:00303342890.223
cyclic nucleotide metabolic processGO:0009187820.222
regulation of cell fate specificationGO:004265950.221
purine nucleoside catabolic processGO:00061523980.219
negative regulation of apoptotic processGO:00430663160.218
head developmentGO:00603221080.217
Mouse
regulation of fat cell differentiationGO:0045598230.217
Human Mouse
cardiac muscle cell differentiationGO:0055007150.215
protein targeting to nucleusGO:00447441040.212
Human
canonical wnt signaling pathway involved in mesenchymal stem cell differentiationGO:004433820.212
negative regulation of cellular amine metabolic processGO:003323930.211
heart morphogenesisGO:0003007480.209
Mouse
regulation of peptidyl serine phosphorylationGO:0033135500.209
positive regulation of cellular catabolic processGO:00313312840.207
regulation of map kinase activityGO:00434051080.206
Human
stress activated protein kinase signaling cascadeGO:0031098940.205
positive regulation of purine nucleotide metabolic processGO:19005442270.205
regulation of jnk cascadeGO:0046328730.204
regulation of cell substrate adhesionGO:0010810680.203
nucleoside phosphate catabolic processGO:19012924120.202
vesicle mediated transportGO:00161923710.202
positive regulation of neural precursor cell proliferationGO:200017920.201
synaptic vesicle exocytosisGO:001607930.200
regulation of muscle cell differentiationGO:0051147310.199
positive regulation of jnk cascadeGO:0046330520.198
positive regulation of cell morphogenesis involved in differentiationGO:0010770500.196
gtp metabolic processGO:00460392390.195
regulation of protein transportGO:00512232130.195
Human
osteoblast differentiationGO:0001649920.193
Human
anion transportGO:00068201610.192
regulation of muscle tissue developmentGO:1901861260.191
Mouse
canonical wnt signaling pathway involved in osteoblast differentiationGO:004433920.191
regulation of axon extension involved in axon guidanceGO:004884120.191
purine nucleoside triphosphate catabolic processGO:00091463920.189
central nervous system developmentGO:00074171230.186
Mouse
cardiac cell fate commitmentGO:006091170.186
brain developmentGO:0007420970.186
Mouse
limbic system developmentGO:002176130.184
purine containing compound catabolic processGO:00725234110.184
negative regulation of cardioblast differentiationGO:005189220.184
regulation of stress activated mapk cascadeGO:0032872840.182
positive regulation of catabolic processGO:00098963100.182
positive regulation of protein catabolic processGO:0045732750.182
negative regulation of multicellular organismal processGO:00512413170.181
Human Mouse
ribonucleotide catabolic processGO:00092614050.181
endocytosisGO:00068971590.179
mesodermal cell differentiationGO:0048333100.179
positive regulation of cell developmentGO:0010720920.178
locomotory behaviorGO:000762610.177
negative regulation of protein metabolic processGO:00512483910.177
positive regulation of proteolysisGO:00458621420.176
negative regulation of axonogenesisGO:005077140.176
regulation of nucleocytoplasmic transportGO:0046822980.176
Human
ion homeostasisGO:00508012300.175
Rat
purine ribonucleoside triphosphate catabolic processGO:00092073910.174
small gtpase mediated signal transductionGO:0007264780.173
response to lipidGO:00339932060.172
glycosyl compound catabolic processGO:19016584130.172
activation of protein kinase activityGO:0032147900.171
regulation of ossificationGO:0030278580.171
Human Mouse
negative regulation of axon guidanceGO:190266810.166
regulation of jun kinase activityGO:0043506270.166
epithelial cell differentiationGO:00308551410.166
regulation of purine nucleotide metabolic processGO:19005422640.164
regulation of bindingGO:00510981110.162
negative regulation of bindingGO:0051100570.162
regulation of cellular response to stressGO:00801352440.162
secretion by cellGO:00329402260.161
ribonucleoside triphosphate catabolic processGO:00092033910.159
positive regulation of kinase activityGO:00336742040.159
Human
positive regulation of purine nucleotide catabolic processGO:00331231850.159
wnt signaling pathway involved in heart developmentGO:000330650.159
Mouse
regulation of gastrulationGO:0010470120.159
system processGO:00030083490.159
Human Fly
organophosphate catabolic processGO:00464344300.158
hematopoietic or lymphoid organ developmentGO:00485341860.158
Human
regulation of microtubule based processGO:0032886740.158
regulation of gtp catabolic processGO:00331241800.157
establishment of tissue polarityGO:000716430.157
axon extensionGO:0048675130.157
regulation of cell motilityGO:20001452990.155
purine ribonucleoside triphosphate metabolic processGO:00092054110.154
response to growth factorGO:00708482050.154
negative regulation of protein modification processGO:00314002000.154
regulation of synaptic vesicle endocytosisGO:190024210.153
wnt signaling pathway planar cell polarity pathwayGO:006007150.152
Mouse
positive regulation of aldosterone biosynthetic processGO:003234920.151
signal transduction by phosphorylationGO:00230142970.151
Human
ossificationGO:00015031210.151
Human Mouse
regulation of embryonic developmentGO:0045995200.151
Mouse
stem cell divisionGO:001714520.150
Mouse
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.150
cell proliferation in forebrainGO:002184610.149
mesenchymal cell developmentGO:0014031500.148
cytoplasmic transportGO:00164823790.148
Human Fly
nucleoside triphosphate catabolic processGO:00091433940.148
regulation of nervous system developmentGO:0051960880.147
Mouse
response to biotic stimulusGO:00096072760.146
oogenesisGO:004847720.146
digestive system developmentGO:0055123750.146
Mouse
negative regulation of striated muscle tissue developmentGO:0045843110.145
Mouse
nucleoside triphosphate metabolic processGO:00091414220.144
regulation of striated muscle cell differentiationGO:0051153250.144
axon extension involved in axon guidanceGO:004884650.144
negative regulation of axon extensionGO:003051720.143
inner ear morphogenesisGO:004247240.143
ribonucleoside triphosphate metabolic processGO:00091994120.142
positive regulation of transferase activityGO:00513472270.142
Human
purine ribonucleoside metabolic processGO:00461284370.141
hemopoiesisGO:00300971800.141
stress activated mapk cascadeGO:0051403930.140
cardioblast cell fate commitmentGO:004268410.139
alcohol metabolic processGO:00060661140.139
neuroblast divisionGO:005505710.138
Mouse
immune system developmentGO:00025201950.137
Human
regulation of cell adhesionGO:00301551660.137
regulation of dopamine receptor signaling pathwayGO:006015930.136
pattern specification processGO:0007389430.136
ameboidal type cell migrationGO:00016671350.134
Mouse
purine ribonucleoside catabolic processGO:00461303980.134
positive regulation of jun kinase activityGO:0043507230.134
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.133
developmental cell growthGO:0048588180.133
cellular response to ammonium ionGO:007124240.133
embryonic heart tube morphogenesisGO:000314380.133
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.132
blastoderm segmentationGO:000735020.132
jnk cascadeGO:0007254800.131
nucleocytoplasmic transportGO:00069131760.131
Human
regulation of secretion by cellGO:19035301770.131
cell cell signaling involved in cell fate commitmentGO:004516850.130
guanosine containing compound catabolic processGO:19010692390.130
cell cell signalingGO:00072671550.130
Rat
chordate embryonic developmentGO:0043009340.129
neuronal stem cell divisionGO:003644510.128
Mouse
positive regulation of collateral sproutingGO:004867220.128
negative regulation of cell proliferationGO:00082852280.127
Mouse
growthGO:00400072020.127
Mouse
retina vasculature morphogenesis in camera type eyeGO:006129930.126
Human
positive regulation of cellular component movementGO:00512721810.126
hair cycleGO:0042633280.125
positive regulation of secretionGO:00510471160.125
positive regulation of endocytosisGO:0045807420.124
positive regulation of protein transportGO:00512221350.123
Human
regulation of protein import into nucleusGO:0042306780.122
Human
regulation of cellular component movementGO:00512703340.120
negative regulation of pathway restricted smad protein phosphorylationGO:0060394110.119
motor neuron axon guidanceGO:000804520.119
negative regulation of transportGO:00510511760.119
Human
muscle structure developmentGO:0061061980.116
Mouse
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.115
regulation of stem cell differentiationGO:2000736560.115
regulation of cell growthGO:00015581350.115
stem cell differentiationGO:0048863930.114
axis elongationGO:000340140.114
Mouse
endothelial cell migrationGO:0043542860.113
protein ubiquitinationGO:00165673140.113
telencephalon developmentGO:0021537170.112
Mouse
positive regulation of intracellular protein transportGO:0090316760.112
Human
collateral sproutingGO:004866820.111
mesoderm morphogenesisGO:0048332110.111
cell projection organizationGO:00300302520.111
canonical wnt signaling pathway involved in regulation of cell proliferationGO:004434020.111
Mouse
cytokine productionGO:00018162470.111
positive regulation of gtpase activityGO:00435471660.111
ras protein signal transductionGO:0007265730.111
regulation of synaptic vesicle recyclingGO:190342110.110
nucleotide catabolic processGO:00091664080.110
cellular protein catabolic processGO:00442572610.110
non canonical wnt signaling pathway via jnk cascadeGO:003803130.109
muscle cell differentiationGO:0042692630.109
regulation of cell projection organizationGO:00313441070.108
establishment of planar polarityGO:000173630.107
regulation of proteolysisGO:00301622930.107
positive regulation of hydrolase activityGO:00513453310.106
regulation of cytoskeleton organizationGO:00514931770.106
positive regulation of steroid hormone biosynthetic processGO:009003120.105
regionalizationGO:0003002290.105
coagulationGO:0050817780.105
cellular response to transforming growth factor beta stimulusGO:0071560940.105
regulation of cell morphogenesisGO:00226041530.105
regulation of endodermal cell fate specificationGO:004266310.105
positive regulation of apoptotic processGO:00430652460.104
Mouse
cardiac cell fate specificationGO:006091210.104
receptor mediated endocytosisGO:0006898840.104
regulation of proteasomal protein catabolic processGO:0061136870.104
protein importGO:00170381300.104
Human
vasculature developmentGO:00019441810.104
Human
behaviorGO:00076101120.103
Fly
regulation of sodium dependent phosphate transportGO:200011820.103
regenerationGO:003109940.103
regulation of epithelial cell migrationGO:0010632930.103
tangential migration from the subventricular zone to the olfactory bulbGO:002202830.102
embryonic organ morphogenesisGO:0048562240.102
Mouse
regulation of neuron differentiationGO:0045664700.102
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101450.102
proteolysis involved in cellular protein catabolic processGO:00516032440.102
nuclear transportGO:00511691790.101
Human
post embryonic developmentGO:000979120.101
regulation of growthGO:00400081650.101
cardioblast cell fate specificationGO:004268510.101
regulation of protein catabolic processGO:00421761550.101
positive regulation of hormone biosynthetic processGO:004688640.101
synaptic vesicle recyclingGO:003646530.100
purine ribonucleotide catabolic processGO:00091544040.099
single organism nuclear importGO:19025931040.099
Human
microtubule based processGO:00070172100.099
positive regulation of cell migrationGO:00303351720.099
female gamete generationGO:000729220.098
regulation of chemotaxisGO:0050920740.098
cell fate specificationGO:000170880.098
morphogenesis of embryonic epitheliumGO:001633140.097
Mouse
protein localization to nucleusGO:00345041360.097
Human
positive regulation of programmed cell deathGO:00430682490.097
Mouse
negative regulation of hydrolase activityGO:00513461820.097
cellular response to oxygen containing compoundGO:19017012760.097
positive regulation of peptidyl serine phosphorylationGO:0033138420.096
synaptic vesicle endocytosisGO:004848820.096
proteasomal protein catabolic processGO:00104981760.096
cellular response to growth factor stimulusGO:00713631970.095
response to woundingGO:00096111680.095
peptidyl serine modificationGO:00182091060.095
protein catabolic processGO:00301633250.095
peptidyl threonine phosphorylationGO:0018107410.094
Human
negative regulation of cellular protein metabolic processGO:00322693530.094
microtubule cytoskeleton organizationGO:00002261760.093
cell growthGO:00160491600.093
signal releaseGO:0023061700.092
cellular macromolecule catabolic processGO:00442653800.092
positive regulation of nucleocytoplasmic transportGO:0046824540.092
Human
retinal ganglion cell axon guidanceGO:003129020.091
neuromuscular junction developmentGO:000752830.091
regulation of nucleoside metabolic processGO:00091182090.091
urogenital system developmentGO:0001655650.090
Human
response to cytokineGO:00340972320.089
positive regulation of cytokine productionGO:00018191670.089
positive regulation of protein bindingGO:0032092240.089
hippocampus developmentGO:002176610.088
guanosine containing compound metabolic processGO:19010682440.088
regulation of stem cell proliferationGO:0072091150.088
Human Mouse
tripartite regional subdivisionGO:000735120.088
positive regulation of axon extensionGO:004577340.088
regulation of microtubule cytoskeleton organizationGO:0070507610.088
anterior posterior axis specification embryoGO:000859520.087
regulation of cyclic nucleotide metabolic processGO:0030799630.087
cellular response to metal ionGO:0071248430.087
positive regulation of mineralocorticoid secretionGO:200085710.086
negative regulation of muscle organ developmentGO:0048635120.086
Mouse
regulation of establishment of protein localizationGO:00702012420.086
Human
regulation of cardioblast cell fate specificationGO:004268610.085
anterior posterior axis specificationGO:000994820.085
Mouse
retina vasculature development in camera type eyeGO:006129830.084
Human
positive regulation of cellular amine metabolic processGO:003324070.083
forebrain developmentGO:0030900260.083
Mouse
negative regulation of catalytic activityGO:00430863350.083
positive regulation of protein kinase activityGO:00458601900.083
Human
epithelial cell migrationGO:00106311190.083
determination of adult lifespanGO:000834020.083
negative regulation of cardioblast cell fate specificationGO:000999710.082
negative regulation of mesodermal cell fate specificationGO:004266210.082
embryonic morphogenesisGO:0048598850.082
Mouse
regulation of gtpase activityGO:00430871800.082
chemotaxisGO:00069351570.082
regulation of cardioblast differentiationGO:005189040.082
response to transforming growth factor betaGO:0071559940.082
membrane organizationGO:00610242920.082
epithelial cell proliferationGO:00506731280.081
Mouse
positive regulation of gtp catabolic processGO:00331261660.080
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.080
biological adhesionGO:00226103310.079
Rat
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayGO:190103030.079
blood vessel morphogenesisGO:00485141620.079
Human
multicellular organismal agingGO:001025930.078
defense responseGO:00069523150.078
cellular response to organic cyclic compoundGO:00714071270.078
regulation of anatomical structure sizeGO:00900661010.078
regulation of epithelial cell proliferationGO:00506781130.077
Mouse
negative regulation of cell projection organizationGO:0031345220.076
regulation of endothelial cell migrationGO:0010594670.076
generation of neuronsGO:00486991520.076
Mouse
negative regulation of cell growthGO:0030308830.076
establishment or maintenance of cytoskeleton polarityGO:003095230.076
mesoderm developmentGO:0007498140.076
dendritic spine morphogenesisGO:006099730.076
regulation of cell maturationGO:190342930.075
appendage morphogenesisGO:0035107160.074
Mouse
regulation of cytokine productionGO:00018172320.074
g protein coupled receptor signaling pathwayGO:00071862070.074
regulation of organ morphogenesisGO:2000027240.074
Mouse
nuclear importGO:00511701060.073
Human
negative regulation of muscle cell differentiationGO:0051148170.073
peptidyl threonine modificationGO:0018210450.072
Human
catenin import into nucleusGO:0035411180.072
Human
positive regulation of secretion by cellGO:19035321080.072
positive regulation of receptor internalizationGO:0002092120.072
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.072
developmental inductionGO:003112850.072
wound healingGO:00420601150.071
positive regulation of cytokine secretion involved in immune responseGO:000274120.070
response to endoplasmic reticulum stressGO:0034976490.070
nucleoside catabolic processGO:00091644080.069
positive regulation of locomotionGO:00400171860.069
rostrocaudal neural tube patterningGO:002190310.069
Mouse
cellular response to dna damage stimulusGO:00069743790.069
single organism membrane organizationGO:00448022680.069
developmental growth involved in morphogenesisGO:0060560230.068
Mouse
positive regulation of protein import into nucleusGO:0042307460.068
Human
molting cycle processGO:0022404120.068
neuron projection extensionGO:1990138140.067
regulation of excitatory postsynaptic membrane potentialGO:006007910.067
protein modification by small protein conjugationGO:00324463420.067
cellular response to cytokine stimulusGO:00713451810.067
positive regulation of cell deathGO:00109422630.067
Mouse
fat cell differentiationGO:0045444320.067
Human Mouse
single organism cell adhesionGO:00986021790.067
Rat
positive regulation of cyclic nucleotide metabolic processGO:0030801490.066
epidermis developmentGO:0008544590.066
salivary gland morphogenesisGO:000743540.066
positive regulation of intracellular transportGO:00323881040.066
Human
endoderm formationGO:0001706330.065
negative regulation of protein phosphorylationGO:00019331400.065
response to metal ionGO:0010038840.065
neuron projection developmentGO:00311751060.065
endoderm developmentGO:0007492330.065
neuroblast proliferationGO:000740540.065
Mouse

LRP6 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
synucleinopathyDOID:0050890220.065
central nervous system diseaseDOID:3311860.065