Homo sapiens

264 known processes

LRP5

low density lipoprotein receptor-related protein 5

(Aliases: HBM,LRP7,OPS,OPTA1,BMND1,LR3,VBCH2,OPPG,EVR4,EVR1)

LRP5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular ketone metabolic processGO:0010565500.337
cellular amine metabolic processGO:0044106410.331
regulation of cellular amine metabolic processGO:0033238110.299
amine metabolic processGO:0009308440.263
regulation of cellular amino acid metabolic processGO:000652160.229
regulation of cell differentiationGO:00455953930.129
cellular ketone metabolic processGO:0042180800.116
positive regulation of protein phosphorylationGO:00019343130.116
Human
positive regulation of cellular component organizationGO:00511303760.115
regulation of canonical wnt signaling pathwayGO:0060828880.114
positive regulation of phosphorylationGO:00423273940.110
Human
positive regulation of cell differentiationGO:00455972110.106
positive regulation of developmental processGO:00510943140.105
cellular amino acid metabolic processGO:00065201160.101
positive regulation of canonical wnt signaling pathwayGO:0090263330.100
Human
cell developmentGO:00484683280.094
Human Mouse
regulation of wnt signaling pathwayGO:00301111230.081
cellular component morphogenesisGO:00329893140.080
Human
cell morphogenesisGO:00009022960.078
Human
post embryonic developmentGO:000979120.070
regulation of anatomical structure morphogenesisGO:00226032860.070
negative regulation of multicellular organismal processGO:00512413170.065
cell projection organizationGO:00300302520.060
enzyme linked receptor protein signaling pathwayGO:00071673030.059
Human
regulation of cell developmentGO:00602841610.058
regulation of cell growthGO:00015581350.058
positive regulation of wnt signaling pathwayGO:0030177540.056
Human
morphogenesis of embryonic epitheliumGO:001633140.054
negative regulation of protein metabolic processGO:00512483910.053
cellular lipid metabolic processGO:00442553030.053
female gamete generationGO:000729220.051
positive regulation of dendrite morphogenesisGO:005077530.051
cell morphogenesis involved in differentiationGO:00009041440.051
Human
positive regulation of cellular amine metabolic processGO:003324070.050
oogenesisGO:004847720.050
positive regulation of cellular amino acid metabolic processGO:004576430.049
multicellular organismal agingGO:001025930.048
response to oxygen containing compoundGO:19017003690.048
Human Mouse Rat
negative regulation of catalytic activityGO:00430863350.047
purine ribonucleotide catabolic processGO:00091544040.047
negative regulation of growthGO:0045926970.046
regulation of cellular component movementGO:00512703340.046
determination of adult lifespanGO:000834020.046
peptidyl serine modificationGO:00182091060.046
cellular response to endogenous stimulusGO:00714953360.046
purine ribonucleoside metabolic processGO:00461284370.045
lipid metabolic processGO:00066293810.045
Mouse
positive regulation of cell developmentGO:0010720920.045
growthGO:00400072020.045
ribonucleotide catabolic processGO:00092614050.045
regulation of transferase activityGO:00513383550.044
negative regulation of cellular protein metabolic processGO:00322693530.043
organophosphate catabolic processGO:00464344300.043
nucleotide catabolic processGO:00091664080.043
purine nucleoside triphosphate catabolic processGO:00091463920.043
purine ribonucleoside triphosphate metabolic processGO:00092054110.042
response to abiotic stimulusGO:00096283360.042
small gtpase mediated signal transductionGO:0007264780.042
regulation of locomotionGO:00400123290.042
purine containing compound catabolic processGO:00725234110.042
neuron differentiationGO:00301821380.042
generation of neuronsGO:00486991520.042
regulation of cell morphogenesisGO:00226041530.042
glycosyl compound catabolic processGO:19016584130.042
nucleoside phosphate catabolic processGO:19012924120.041
positive regulation of hydrolase activityGO:00513453310.041
negative regulation of phosphorus metabolic processGO:00105632670.040
positive regulation of catabolic processGO:00098963100.040
positive regulation of cell proliferationGO:00082843010.039
ras protein signal transductionGO:0007265730.039
cellular response to oxygen containing compoundGO:19017012760.039
Human Mouse
ribonucleoside triphosphate metabolic processGO:00091994120.039
nucleoside catabolic processGO:00091644080.039
purine ribonucleoside triphosphate catabolic processGO:00092073910.039
regulation of cell motilityGO:20001452990.039
regulation of growthGO:00400081650.039
neurogenesisGO:00220081690.038
nucleoside triphosphate metabolic processGO:00091414220.038
peptidyl serine phosphorylationGO:00181051010.038
single organism cellular localizationGO:19025803320.038
Human Fly
dendritic spine morphogenesisGO:006099730.038
regulation of cell cycleGO:00517263930.037
negative regulation of protein modification processGO:00314002000.037
segmentationGO:003528240.037
locomotory behaviorGO:000762610.037
negative regulation of phosphate metabolic processGO:00459362670.037
epithelium developmentGO:00604292270.037
Mouse
cell projection morphogenesisGO:00488581290.037
cell growthGO:00160491600.036
regulation of cell projection organizationGO:00313441070.036
biological adhesionGO:00226103310.036
purine nucleoside triphosphate metabolic processGO:00091444120.036
purine nucleotide catabolic processGO:00061954050.036
nervous system developmentGO:00073992930.036
Fly
regulation of nucleotide metabolic processGO:00061402690.035
purine nucleoside catabolic processGO:00061523980.035
negative regulation of cell growthGO:0030308830.034
nucleoside triphosphate catabolic processGO:00091433940.034
carbohydrate metabolic processGO:00059752070.034
rho protein signal transductionGO:0007266260.033
regulation of nervous system developmentGO:0051960880.033
regulation of bindingGO:00510981110.033
positive regulation of cellular catabolic processGO:00313312840.033
ribonucleoside triphosphate catabolic processGO:00092033910.033
purine ribonucleoside catabolic processGO:00461303980.033
positive regulation of cell morphogenesis involved in differentiationGO:0010770500.033
regulation of establishment of protein localizationGO:00702012420.033
Human
regulation of protein kinase activityGO:00458592890.032
negative regulation of cell deathGO:00605483450.032
Human
ribonucleoside catabolic processGO:00424544060.032
regulation of neuron differentiationGO:0045664700.032
carbohydrate derivative biosynthetic processGO:19011372070.032
Human
canonical wnt signaling pathwayGO:00600701160.031
regulation of proteolysisGO:00301622930.031
chemical homeostasisGO:00488783060.031
wnt signaling pathwayGO:00160551560.031
neuron projection developmentGO:00311751060.031
neuron developmentGO:00486661130.030
cell part morphogenesisGO:00329901370.030
cytoplasmic transportGO:00164823790.030
Human Fly
regulation of nucleoside metabolic processGO:00091182090.030
regulation of protein localizationGO:00328802960.029
Human
oxidation reduction processGO:00551143960.029
hindbrain developmentGO:003090230.029
peripheral nervous system developmentGO:000742220.029
system processGO:00030083490.029
regulation of cell migrationGO:00303342890.029
embryonic epithelial tube formationGO:000183840.029
regulation of kinase activityGO:00435493140.029
actin filament based processGO:00300292240.029
negative regulation of cellular component organizationGO:00511292350.029
transmembrane transportGO:00550853990.029
Human
negative regulation of cell proliferationGO:00082852280.029
organic hydroxy compound metabolic processGO:19016151470.028
Mouse
regulation of mapk cascadeGO:00434082620.028
Human
signal transduction by phosphorylationGO:00230142970.028
Human
cell adhesionGO:00071553250.028
regulation of neurogenesisGO:0050767820.028
negative regulation of cell migrationGO:00303361020.028
anterior posterior axis specificationGO:000994820.028
membrane organizationGO:00610242920.028
positive regulation of purine nucleotide catabolic processGO:00331231850.028
mapk cascadeGO:00001652880.028
Human
protein maturationGO:00516042330.028
single organism carbohydrate metabolic processGO:00447231930.028
mitotic cell cycleGO:00002783260.028
regulation of neuron projection developmentGO:0010975570.027
positive regulation of transferase activityGO:00513472270.027
Human
positive regulation of nucleotide metabolic processGO:00459812300.027
regulation of protein bindingGO:0043393660.027
immune responseGO:00069553070.027
monocarboxylic acid metabolic processGO:00327871850.027
negative regulation of locomotionGO:00400131180.027
response to lipidGO:00339932060.027
Human
regenerationGO:003109940.027
neuromuscular junction developmentGO:000752830.027
regulation of purine nucleotide metabolic processGO:19005422640.027
blastoderm segmentationGO:000735020.027
response to growth factorGO:00708482050.027
intracellular protein transportGO:00068862700.027
Human Fly
protein processingGO:00164852260.026
regulation of gtp catabolic processGO:00331241800.026
negative regulation of apoptotic processGO:00430663160.026
Human
lipid biosynthetic processGO:00086101770.026
negative regulation of cellular component movementGO:00512711060.026
negative regulation of phosphorylationGO:00423261740.026
oocyte differentiationGO:000999420.026
cell fate determinationGO:000170930.026
cellular response to dna damage stimulusGO:00069743790.026
positive regulation of protein kinase activityGO:00458601900.026
Human
positive regulation of nucleotide catabolic processGO:00308131850.026
regulation of purine nucleotide catabolic processGO:00331212050.025
oocyte developmentGO:004859910.025
memoryGO:000761330.025
Fly
positive regulation of transportGO:00510503360.025
Human
guanosine containing compound catabolic processGO:19010692390.025
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.025
secretionGO:00469032540.025
Human Mouse
positive regulation of protein bindingGO:0032092240.025
positive regulation of purine nucleotide metabolic processGO:19005442270.025
gtp catabolic processGO:00061842370.025
single organism membrane organizationGO:00448022680.024
positive regulation of apoptotic processGO:00430652460.024
apoptotic signaling pathwayGO:00971902680.024
defense responseGO:00069523150.024
regulation of gtpase activityGO:00430871800.024
positive regulation of bindingGO:0051099450.024
positive regulation of neurogenesisGO:0050769490.024
small molecule biosynthetic processGO:00442831570.024
organonitrogen compound biosynthetic processGO:19015662000.024
Human
guanosine containing compound metabolic processGO:19010682440.024
negative regulation of developmental processGO:00510932470.024
peptidyl tyrosine modificationGO:00182121700.024
Human
protein localization to organelleGO:00333652800.023
Human Fly
regulation of cellular response to stressGO:00801352440.023
gtp metabolic processGO:00460392390.023
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.023
Human
ion homeostasisGO:00508012300.023
neural tube formationGO:000184130.023
regulation of cellular component biogenesisGO:00440872810.023
positive regulation of kinase activityGO:00336742040.023
Human
circulatory system developmentGO:00723592620.022
negative regulation of wnt signaling pathwayGO:0030178690.022
Human
negative regulation of programmed cell deathGO:00430693210.022
Human
positive regulation of cell deathGO:00109422630.022
negative regulation of cellular amine metabolic processGO:003323930.022
peptidyl tyrosine phosphorylationGO:00181081700.022
Human
positive regulation of gtp catabolic processGO:00331261660.022
dephosphorylationGO:00163112090.022
endomembrane system organizationGO:00102561960.022
epithelial cell differentiationGO:00308551410.022
regulation of ras protein signal transductionGO:00465781550.022
cellular macromolecular complex assemblyGO:00346223240.022
metal ion transportGO:00300012720.021
Human
regulation of peptidyl serine phosphorylationGO:0033135500.021
positive regulation of mapk cascadeGO:00434101900.021
Human
neurological system processGO:00508771630.021
Fly
glycoprotein metabolic processGO:00091001100.021
blood vessel morphogenesisGO:00485141620.021
regulation of protein serine threonine kinase activityGO:00719001790.021
positive regulation of nucleoside metabolic processGO:00459791860.021
regulation of cell cycle processGO:00105642660.021
regulation of sequence specific dna binding transcription factor activityGO:00510902110.021
Human Mouse
response to organic cyclic compoundGO:00140702040.021
Human
vasculature developmentGO:00019441810.021
vesicle mediated transportGO:00161923710.021
Human
protein catabolic processGO:00301633250.021
regulation of peptidase activityGO:00525471800.021
cellular macromolecule catabolic processGO:00442653800.020
chromatin organizationGO:00063253510.020
carboxylic acid biosynthetic processGO:0046394970.020
cardiovascular system developmentGO:00723582620.020
positive regulation of peptidyl serine phosphorylationGO:0033138420.020
positive regulation of immune system processGO:00026842830.020
cellular response to growth factor stimulusGO:00713631970.020
organic acid biosynthetic processGO:0016053970.020
inner ear morphogenesisGO:004247240.020
regulation of nucleotide catabolic processGO:00308112050.020
regulation of cytokine productionGO:00018172320.020
regulation of mitotic cell cycleGO:00073461890.020
cation transportGO:00068123310.020
Human
negative regulation of transportGO:00510511760.020
Human
positive regulation of gtpase activityGO:00435471660.020
primary neural tube formationGO:001402030.020
fatty acid metabolic processGO:00066311150.020
plasma membrane organizationGO:00070091150.020
blood vessel developmentGO:00015681720.020
negative regulation of cellular amino acid metabolic processGO:004576320.020
negative regulation of protein phosphorylationGO:00019331400.020
mitotic cell cycle processGO:19030472860.020
innate immune responseGO:00450871780.020
response to hormoneGO:00097251750.020
Rat
ameboidal type cell migrationGO:00016671350.020
Mouse
negative regulation of intracellular signal transductionGO:19025321830.020
cellular response to organic cyclic compoundGO:00714071270.020
Human
protein localization to membraneGO:00726571600.020
regulation of cytoskeleton organizationGO:00514931770.019
positive regulation of neuron differentiationGO:0045666400.019
anatomical structure formation involved in morphogenesisGO:00486462840.019
Human Mouse
regulation of protein transportGO:00512232130.019
Human
response to other organismGO:00517072610.019
microtubule based processGO:00070172100.019
posttranscriptional regulation of gene expressionGO:00106082130.019
microtubule cytoskeleton organizationGO:00002261760.019
response to external biotic stimulusGO:00432072610.019
spermatid differentiationGO:004851540.019
regulation of small gtpase mediated signal transductionGO:00510561560.019
negative regulation of hydrolase activityGO:00513461820.019
negative regulation of cell differentiationGO:00455961710.019
response to nitrogen compoundGO:19016981840.019
Rat
negative regulation of cell motilityGO:20001461040.019
single organismal cell cell adhesionGO:00163371480.019
response to biotic stimulusGO:00096072760.018
single organism cell adhesionGO:00986021790.018
chemotaxisGO:00069351570.018
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.018
cellular protein catabolic processGO:00442572610.018
positive regulation of nervous system developmentGO:0051962540.018
regulation of endopeptidase activityGO:00525481700.018
response to cytokineGO:00340972320.018
adult locomotory behaviorGO:000834410.018
positive regulation of locomotionGO:00400171860.018
cellular homeostasisGO:00197251960.018
Mouse
positive regulation of dendritic spine developmentGO:006099920.018
metencephalon developmentGO:002203720.018
ion transmembrane transportGO:00342203380.018
Human
taxisGO:00423301570.018
cdc42 protein signal transductionGO:003248840.018
protein oligomerizationGO:00512591730.018
cytokine productionGO:00018162470.018
anterior posterior axis specification embryoGO:000859520.018
positive regulation of cellular component movementGO:00512721810.018
nitrogen compound transportGO:00717051910.018
Mouse
central nervous system developmentGO:00074171230.018
positive regulation of cell migrationGO:00303351720.018
epithelial cell migrationGO:00106311190.018
organophosphate biosynthetic processGO:00904071630.018
regulation of cell adhesionGO:00301551660.018
chromatin modificationGO:00165682980.018
photoreceptor cell differentiationGO:004653020.017
hemopoiesisGO:00300971800.017
cation homeostasisGO:00550801890.017
positive regulation of neuron projection developmentGO:0010976340.017
regulation of secretionGO:00510461940.017
Human Mouse
epithelium migrationGO:00901321190.017
tripartite regional subdivisionGO:000735120.017
maintenance of locationGO:00512351120.017
positive regulation of programmed cell deathGO:00430682490.017
nucleocytoplasmic transportGO:00069131760.017
Human
tissue migrationGO:00901301190.017
negative regulation of cell cycleGO:00457861930.017
morphogenesis of a polarized epitheliumGO:000173830.017
anion transportGO:00068201610.017
rhythmic behaviorGO:000762220.017
tube developmentGO:00352951250.017
Mouse
actin cytoskeleton organizationGO:00300362070.017
tube closureGO:006060630.017
motor neuron axon guidanceGO:000804520.017
cell activationGO:00017752130.017
regulation of response to external stimulusGO:00321012220.017
cellular response to cytokine stimulusGO:00713451810.017
regulation of protein catabolic processGO:00421761550.017
compound eye developmentGO:004874910.016
Fly
positive regulation of cell motilityGO:20001471770.016
cellular response to hormone stimulusGO:00328701250.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
mitochondrion organizationGO:00070051560.016
regulation of peptidyl tyrosine phosphorylationGO:00507301080.016
Human
somitogenesisGO:000175620.016
regulation of protein complex assemblyGO:00432541470.016
sulfur compound metabolic processGO:00067901010.016
dendritic spine organizationGO:009706140.016
secretion by cellGO:00329402260.016
Mouse
hematopoietic or lymphoid organ developmentGO:00485341860.016
melanin metabolic processGO:000658210.016
reactive nitrogen species metabolic processGO:200105730.016
spermatid developmentGO:000728640.016
regulation of ras gtpase activityGO:00323181280.016
axis elongationGO:000340140.016
cell substrate adhesionGO:00315891320.016
regulation of synaptic plasticityGO:004816730.016
ossificationGO:00015031210.016
protein ubiquitinationGO:00165673140.016
leukocyte activationGO:00453211640.016
angiogenesisGO:00015251470.016
Human Mouse
positive regulation of ras gtpase activityGO:00323201170.015
neuroblast proliferationGO:000740540.015
establishment of protein localization to membraneGO:00901501210.015
regulation of protein maturationGO:19033171500.015
negative regulation of kinase activityGO:00336731060.015
reactive oxygen species metabolic processGO:0072593750.015
negative regulation of protein kinase activityGO:0006469980.015
organic anion transportGO:00157111030.015
circadian behaviorGO:004851220.015
histone modificationGO:00165702510.015
regulation of intracellular transportGO:00323861950.015
Human
epithelial cell proliferationGO:00506731280.015
organelle assemblyGO:00709251760.015
protein targetingGO:00066051870.015
Human Fly
nuclear transportGO:00511691790.015
Human
forebrain generation of neuronsGO:002187230.015
alcohol metabolic processGO:00060661140.015
Mouse
salivary gland morphogenesisGO:000743540.015
negative regulation of proteolysisGO:00458611320.015
cell projection assemblyGO:00300311260.015
regulation of neural precursor cell proliferationGO:200017740.015
reactive oxygen species biosynthetic processGO:190340940.015
response to woundingGO:00096111680.015
negative regulation of transferase activityGO:00513481240.015
regulation of secretion by cellGO:19035301770.015
Mouse
positive regulation of synaptic transmissionGO:005080640.015
protein modification by small protein conjugationGO:00324463420.015
nucleoside monophosphate metabolic processGO:00091231910.015
mitotic cell cycle phase transitionGO:00447721620.015
limbic system developmentGO:002176130.015
negative regulation of canonical wnt signaling pathwayGO:0090090550.015
Human
spinal cord developmentGO:002151040.015
organ formationGO:004864530.015
cell cycle phase transitionGO:00447701730.015
lipid catabolic processGO:0016042840.015
thymus developmentGO:004853830.015
protein importGO:00170381300.015
Human
embryonic camera type eye developmentGO:003107620.014
negative regulation of protein maturationGO:19033181420.014
neural tube closureGO:000184330.014
positive regulation of proteolysisGO:00458621420.014
cell divisionGO:00513011680.014
proteasomal protein catabolic processGO:00104981760.014
modification dependent macromolecule catabolic processGO:00436322120.014
cellular cation homeostasisGO:00300031630.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
covalent chromatin modificationGO:00165692540.014
regulation of axon guidanceGO:190266730.014
retinal ganglion cell axon guidanceGO:003129020.014
matingGO:000761810.014
regulation of cysteine type endopeptidase activityGO:20001161270.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
regulation of protein processingGO:00706131500.014
establishment of protein localization to organelleGO:00725941720.014
Human Fly
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
organ morphogenesisGO:00098871470.014
neuron fate commitmentGO:004866320.014
cell type specific apoptotic processGO:00972851250.014
Human
cellular protein complex assemblyGO:00436231880.014
neural crest cell developmentGO:001403230.014
glial cell migrationGO:000834740.014
small molecule catabolic processGO:0044282920.014
forelimb morphogenesisGO:003513640.014
ubiquitin dependent protein catabolic processGO:00065112060.014
embryonic morphogenesisGO:0048598850.014
Mouse
atp metabolic processGO:00460341760.014
endothelial cell migrationGO:0043542860.014
cellular ion homeostasisGO:00068731680.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
regulation of immune responseGO:00507762010.014
protein autophosphorylationGO:00467771230.014
cellular carbohydrate metabolic processGO:0044262840.014
neuron projection morphogenesisGO:0048812500.014
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.014
modification dependent protein catabolic processGO:00199412090.014
neurotransmitter secretionGO:000726940.013
protein homooligomerizationGO:00512601000.013
regulation of dna metabolic processGO:00510521530.013
lipid transportGO:0006869900.013
cellular response to lipidGO:00713961270.013
Human
tissue regenerationGO:004224630.013
actin filament organizationGO:00070151280.013
establishment of planar polarityGO:000173630.013
metal ion homeostasisGO:00550651690.013
positive regulation of cell cycleGO:00457871400.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.013
rna processingGO:00063962550.013
regulation of intracellular protein transportGO:00331571230.013
Human
syncytium formation by plasma membrane fusionGO:000076820.013
cellular response to nitrogen compoundGO:19016991440.013
regulation of reactive oxygen species metabolic processGO:2000377410.013
erk1 and erk2 cascadeGO:00703711040.013
Human
glycoprotein biosynthetic processGO:0009101910.013
regulation of defense responseGO:00313471540.013
immune system developmentGO:00025201950.013
lung alveolus developmentGO:004828640.013
regulation of apoptotic signaling pathwayGO:20012331750.013
positive regulation of organelle organizationGO:00106381950.013
nerve developmentGO:002167540.013
skeletal system developmentGO:0001501790.013
regulation of epithelial cell proliferationGO:00506781130.013
cation transmembrane transportGO:00986552380.013
protein localization to plasma membraneGO:0072659930.013
cardiac muscle cell contractionGO:008600340.013
stress activated mapk cascadeGO:0051403930.013
organelle fissionGO:00482851490.013
head developmentGO:00603221080.013
cell chemotaxisGO:00603261120.013
convergent extensionGO:006002610.013
sensory perception of painGO:001923340.012
inorganic ion transmembrane transportGO:00986602310.012
negative regulation of protein processingGO:00109551420.012
t cell differentiation in thymusGO:003307740.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
sex determinationGO:000753030.012
post embryonic organ developmentGO:004856910.012
lymphocyte activationGO:00466491330.012
startle responseGO:000196430.012
embryonic placenta developmentGO:000189210.012
embryonic forelimb morphogenesisGO:003511540.012
inorganic cation transmembrane transportGO:00986621940.012
atp catabolic processGO:00062001570.012
peptidyl lysine modificationGO:00182051440.012
regulation of ion transportGO:00432691890.012
Human
actin mediated cell contractionGO:0070252120.012
response to oxygen levelsGO:00704821000.012
reproductive processGO:00224141060.012
tissue morphogenesisGO:0048729960.012
cellular chemical homeostasisGO:00550821800.012
Mouse

LRP5 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.050
inherited metabolic disorderDOID:6552420.044
musculoskeletal system diseaseDOID:172230.043
connective tissue diseaseDOID:651090.027
bone diseaseDOID:0080001880.026
sensory system diseaseDOID:00501552030.024
nervous system diseaseDOID:8634310.024
eye diseaseDOID:56141490.021
eye and adnexa diseaseDOID:14921500.021
central nervous system diseaseDOID:3311860.020
cancerDOID:1621670.020
disease of cellular proliferationDOID:145661740.020
organ system cancerDOID:00506861640.018
retinal diseaseDOID:56791180.015
cardiovascular system diseaseDOID:12871060.014
muscular diseaseDOID:00800001140.014
muscle tissue diseaseDOID:661130.014
myopathyDOID:4231040.014
neurodegenerative diseaseDOID:12891020.013