Homo sapiens

0 known processes

PLEKHF2

pleckstrin homology domain containing, family F (with FYVE domain) member 2

(Aliases: PHAFIN2,ZFYVE18,FLJ13187)

PLEKHF2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
histone h3 acetylationGO:0043966450.561
endoplasmic reticulum tubular network organizationGO:007178680.489
histone h4 acetylationGO:0043967470.406
histone acetylationGO:0016573930.328
guanosine containing compound metabolic processGO:19010682440.305
internal protein amino acid acetylationGO:00064751010.278
internal peptidyl lysine acetylationGO:0018393970.273
peptidyl lysine modificationGO:00182051440.271
regulation of anatomical structure sizeGO:00900661010.253
regulation of cell motilityGO:20001452990.253
ribose phosphate biosynthetic processGO:0046390820.249
negative regulation of axon extensionGO:003051720.238
carbohydrate derivative biosynthetic processGO:19011372070.212
regulation of cellular component sizeGO:0032535820.194
cellular macromolecule catabolic processGO:00442653800.175
chromatin organizationGO:00063253510.153
negative regulation of phosphorus metabolic processGO:00105632670.148
memoryGO:000761330.138
regulation of locomotionGO:00400123290.125
purine nucleoside triphosphate metabolic processGO:00091444120.112
peptidyl serine modificationGO:00182091060.108
purine nucleoside triphosphate catabolic processGO:00091463920.102
anterior posterior axis specificationGO:000994820.097
segmentationGO:003528240.094
sleepGO:003043120.089
negative regulation of multicellular organismal processGO:00512413170.089
organophosphate catabolic processGO:00464344300.087
ras protein signal transductionGO:0007265730.086
peptidyl lysine acetylationGO:00183941010.085
tube closureGO:006060630.084
small gtpase mediated signal transductionGO:0007264780.084
regulation of cellular amino acid metabolic processGO:000652160.083
circadian sleep wake cycle processGO:002241020.082
regulation of proteasomal protein catabolic processGO:0061136870.077
ribonucleoside triphosphate catabolic processGO:00092033910.077
peptidyl serine phosphorylationGO:00181051010.073
histone modificationGO:00165702510.072
organophosphate biosynthetic processGO:00904071630.071
negative regulation of growthGO:0045926970.070
gtp catabolic processGO:00061842370.070
glycosyl compound catabolic processGO:19016584130.069
regulation of proteolysisGO:00301622930.068
regulation of cellular component biogenesisGO:00440872810.067
positive regulation of apoptotic processGO:00430652460.067
anterograde axon cargo transportGO:000808910.065
negative regulation of protein metabolic processGO:00512483910.064
nucleoside triphosphate metabolic processGO:00091414220.062
histone h4 k8 acetylationGO:0043982150.059
cilium assemblyGO:0042384630.059
negative regulation of axonogenesisGO:005077140.057
ribonucleotide catabolic processGO:00092614050.056
guanosine containing compound catabolic processGO:19010692390.051
cellular response to external stimulusGO:00714961110.051
oocyte differentiationGO:000999420.051
post embryonic developmentGO:000979120.051
oocyte developmentGO:004859910.050
regulation of anatomical structure morphogenesisGO:00226032860.050
protein acetylationGO:00064731160.050
regulation of nucleotide catabolic processGO:00308112050.050
negative regulation of cell growthGO:0030308830.049
regulation of oocyte developmentGO:006028110.048
cellular amine metabolic processGO:0044106410.048
chromatin modificationGO:00165682980.047
purine ribonucleoside metabolic processGO:00461284370.047
regulation of cellular protein catabolic processGO:1903362960.045
ribonucleoside triphosphate metabolic processGO:00091994120.044
neurotransmitter secretionGO:000726940.043
regulation of synaptic vesicle exocytosisGO:200030020.042
regulation of cell migrationGO:00303342890.042
cellular response to hormone stimulusGO:00328701250.042
covalent chromatin modificationGO:00165692540.041
circadian sleep wake cycleGO:004274520.041
regulation of cell projection organizationGO:00313441070.041
regulation of actin cytoskeleton organizationGO:00329561160.040
regulation of growthGO:00400081650.040
optic nerve developmentGO:002155420.039
blood vessel morphogenesisGO:00485141620.039
purine ribonucleoside triphosphate metabolic processGO:00092054110.038
regulation of protein processingGO:00706131500.037
cell developmentGO:00484683280.037
Fly
regulation of secretion by cellGO:19035301770.036
angiogenesisGO:00015251470.036
purine ribonucleoside triphosphate catabolic processGO:00092073910.036
positive regulation of cell proliferationGO:00082843010.036
actin filament based processGO:00300292240.035
regulation of cellular component movementGO:00512703340.035
anatomical structure formation involved in morphogenesisGO:00486462840.035
endoplasmic reticulum organizationGO:0007029200.034
chemical homeostasisGO:00488783060.034
regulation of natural killer cell activationGO:003281490.034
negative regulation of cellular amine metabolic processGO:003323930.034
blood vessel developmentGO:00015681720.034
negative regulation of cellular protein metabolic processGO:00322693530.034
neural tube formationGO:000184130.034
purine ribonucleoside catabolic processGO:00461303980.033
negative regulation of programmed cell deathGO:00430693210.033
negative regulation of catabolic processGO:00098951040.033
ribonucleotide biosynthetic processGO:0009260810.033
neural tube closureGO:000184330.032
negative regulation of cell differentiationGO:00455961710.032
cell projection morphogenesisGO:00488581290.031
Fly
primary neural tube formationGO:001402030.031
glycerolipid metabolic processGO:00464861070.031
regulation of cell differentiationGO:00455953930.031
endosomal transportGO:00161971290.031
Fly
associative learningGO:000830610.031
establishment or maintenance of apical basal cell polarityGO:003508820.031
actin cytoskeleton organizationGO:00300362070.031
cell morphogenesisGO:00009022960.030
Fly
female gamete generationGO:000729220.030
proteasomal protein catabolic processGO:00104981760.030
positive regulation of purine nucleotide metabolic processGO:19005442270.030
nervous system developmentGO:00073992930.030
Fly
epithelial cell differentiationGO:00308551410.030
negative regulation of cell proliferationGO:00082852280.030
mapk cascadeGO:00001652880.030
regulation of rho gtpase activityGO:0032319660.029
regulation of protein catabolic processGO:00421761550.029
canonical wnt signaling pathwayGO:00600701160.029
proteolysis involved in cellular protein catabolic processGO:00516032440.029
endomembrane system organizationGO:00102561960.029
Human Fly
neurogenesisGO:00220081690.029
Fly
actin polymerization or depolymerizationGO:0008154560.028
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.028
vasculature developmentGO:00019441810.028
regulation of protein kinase activityGO:00458592890.028
actin filament organizationGO:00070151280.027
negative regulation of actin filament polymerizationGO:0030837100.027
regulation of cell maturationGO:190342930.027
histone h2a acetylationGO:0043968120.027
establishment or maintenance of bipolar cell polarityGO:006124520.027
regulation of ras gtpase activityGO:00323181280.027
regulation of circadian sleep wake cycleGO:004274920.027
cellular response to oxygen containing compoundGO:19017012760.026
regulation of stress activated protein kinase signaling cascadeGO:0070302850.026
long term memoryGO:000761620.026
regulation of cell growthGO:00015581350.026
rho protein signal transductionGO:0007266260.025
protein processingGO:00164852260.025
regulation of establishment of cell polarityGO:200011450.025
negative regulation of cell projection organizationGO:0031345220.025
apoptotic signaling pathwayGO:00971902680.025
negative regulation of embryonic developmentGO:004599240.025
cellular amino acid metabolic processGO:00065201160.025
cell projection organizationGO:00300302520.025
Fly
negative regulation of transferase activityGO:00513481240.025
negative regulation of cellular component organizationGO:00511292350.025
cell projection assemblyGO:00300311260.024
embryonic epithelial tube formationGO:000183840.024
regulation of cytoplasmic transportGO:19036491490.024
cranial nerve developmentGO:002154540.024
regulation of actin filament lengthGO:0030832560.024
positive regulation of gtpase activityGO:00435471660.024
amine metabolic processGO:0009308440.024
regulation of establishment of protein localizationGO:00702012420.024
circadian sleep wake cycle sleepGO:005080220.024
cerebral cortex radially oriented cell migrationGO:002179910.024
negative regulation of cell developmentGO:0010721480.024
neural tube patterningGO:002153220.024
positive regulation of nucleotide metabolic processGO:00459812300.023
regulation of gtpase activityGO:00430871800.023
positive regulation of gtp catabolic processGO:00331261660.023
regulation of protein localizationGO:00328802960.022
cilium organizationGO:0044782680.022
signal transduction by phosphorylationGO:00230142970.022
purine nucleoside catabolic processGO:00061523980.022
epithelial cell proliferationGO:00506731280.022
nucleotide biosynthetic processGO:00091651090.022
negative regulation of catalytic activityGO:00430863350.022
regulation of neural precursor cell proliferationGO:200017740.022
nucleoside triphosphate catabolic processGO:00091433940.022
blastoderm segmentationGO:000735020.022
histone h4 k12 acetylationGO:004398360.022
lymphocyte homeostasisGO:000226040.022
nucleoside catabolic processGO:00091644080.021
positive regulation of adenylate cyclase activityGO:0045762120.021
protein acylationGO:00435431380.021
cell growthGO:00160491600.021
regulation of body fluid levelsGO:0050878990.021
antigen processing and presentationGO:0019882330.021
negative regulation of developmental processGO:00510932470.021
negative regulation of protein processingGO:00109551420.021
regulation of ras protein signal transductionGO:00465781550.020
regulation of cell morphogenesisGO:00226041530.020
nuclear divisionGO:00002801280.020
determination of dorsal ventral asymmetryGO:004826240.020
stress activated mapk cascadeGO:0051403930.020
regulation of purine nucleotide metabolic processGO:19005422640.020
membrane organizationGO:00610242920.020
Human
cellular protein catabolic processGO:00442572610.020
protein catabolic processGO:00301633250.020
regulation of protein maturationGO:19033171500.020
regulation of nucleotide metabolic processGO:00061402690.020
regulation of protein polymerizationGO:0032271630.020
nucleoside phosphate biosynthetic processGO:19012931090.019
positive regulation of camp biosynthetic processGO:0030819350.019
regulation of protein stabilityGO:0031647870.019
regulation of epithelial cell proliferationGO:00506781130.019
receptor metabolic processGO:0043112810.019
anterior posterior axis specification embryoGO:000859520.019
response to oxygen containing compoundGO:19017003690.019
negative regulation of neurogenesisGO:0050768260.019
negative regulation of apoptotic processGO:00430663160.019
regulation of jnk cascadeGO:0046328730.019
cellular component morphogenesisGO:00329893140.018
Fly
negative regulation of cell deathGO:00605483450.018
negative regulation of protein polymerizationGO:0032272160.018
positive regulation of purine nucleotide biosynthetic processGO:1900373380.018
negative regulation of smoothened signaling pathwayGO:004587930.018
nucleoside phosphate catabolic processGO:19012924120.018
negative regulation of cell cycleGO:00457861930.018
negative regulation of cellular catabolic processGO:0031330830.018
peripheral nervous system developmentGO:000742220.018
regulation of cellular response to stressGO:00801352440.018
positive regulation of hydrolase activityGO:00513453310.018
regulation of mapk cascadeGO:00434082620.018
negative regulation of phosphorylationGO:00423261740.018
circulatory system developmentGO:00723592620.018
response to nitrogen compoundGO:19016981840.017
tripartite regional subdivisionGO:000735120.017
engulfment of apoptotic cellGO:004365220.017
response to monosaccharideGO:0034284200.017
cell adhesionGO:00071553250.017
ribonucleoside catabolic processGO:00424544060.017
regulation of cellular amine metabolic processGO:0033238110.017
circadian behaviorGO:004851220.017
positive regulation of secretionGO:00510471160.017
purine containing compound catabolic processGO:00725234110.017
golgi organizationGO:0007030380.017
alcohol biosynthetic processGO:0046165520.016
secretion by cellGO:00329402260.016
cytokine productionGO:00018162470.016
negative regulation of transportGO:00510511760.016
positive regulation of purine nucleotide catabolic processGO:00331231850.016
glycerolipid biosynthetic processGO:0045017510.016
histone h4 k5 acetylationGO:0043981150.016
small molecule biosynthetic processGO:00442831570.016
negative regulation of cytoskeleton organizationGO:0051494450.016
negative regulation of intracellular signal transductionGO:19025321830.016
coagulationGO:0050817780.016
purine nucleotide catabolic processGO:00061954050.016
cell morphogenesis involved in differentiationGO:00009041440.016
response to axon injuryGO:004867810.016
regulation of transferase activityGO:00513383550.016
posttranscriptional regulation of gene expressionGO:00106082130.015
microtubule based processGO:00070172100.015
gtp metabolic processGO:00460392390.015
exocytosisGO:0006887710.015
protein localization to plasma membraneGO:0072659930.015
Human
positive regulation of rho gtpase activityGO:0032321560.015
regulation of nucleoside metabolic processGO:00091182090.015
cell type specific apoptotic processGO:00972851250.015
regulation of cytoskeleton organizationGO:00514931770.015
regulation of cytokine productionGO:00018172320.015
negative regulation of phosphate metabolic processGO:00459362670.014
negative regulation of protein kinase activityGO:0006469980.014
barbed end actin filament cappingGO:005101630.014
regulation of rho protein signal transductionGO:0035023790.014
regulation of cell projection assemblyGO:0060491470.014
protein maturationGO:00516042330.014
cellular response to nitrogen compoundGO:19016991440.014
purine containing compound biosynthetic processGO:0072522880.014
morphogenesis of a polarized epitheliumGO:000173830.014
stress activated protein kinase signaling cascadeGO:0031098940.014
regulation of protein serine threonine kinase activityGO:00719001790.014
actin filament cappingGO:005169340.014
system processGO:00030083490.014
spermatid differentiationGO:004851540.014
mitochondrion organizationGO:00070051560.014
regulation of cyclase activityGO:0031279190.014
positive regulation of epithelial cell proliferationGO:0050679650.014
alcohol metabolic processGO:00060661140.014
cell part morphogenesisGO:00329901370.014
Fly
establishment of vesicle localizationGO:0051650230.014
positive regulation of cellular component organizationGO:00511303760.014
cerebral cortex cell migrationGO:002179530.014
organic hydroxy compound biosynthetic processGO:1901617710.013
negative regulation of protein catabolic processGO:0042177590.013
neuroblast proliferationGO:000740540.013
cellular response to organonitrogen compoundGO:00714171240.013
regulation of intracellular transportGO:00323861950.013
oocyte maturationGO:000155610.013
purine ribonucleotide catabolic processGO:00091544040.013
regulation of kinase activityGO:00435493140.013
plasma membrane to endosome transportGO:004822760.013
negative regulation of hydrolase activityGO:00513461820.013
regulation of purine nucleotide catabolic processGO:00331212050.013
ubiquitin dependent protein catabolic processGO:00065112060.013
morphogenesis of embryonic epitheliumGO:001633140.013
regulation of actin filament polymerizationGO:0030833500.013
response to starvationGO:0042594590.013
positive regulation of catabolic processGO:00098963100.013
Human
regulation of small gtpase mediated signal transductionGO:00510561560.013
actin filament polymerizationGO:0030041450.013
cellular response to endogenous stimulusGO:00714953360.013
positive regulation of cell deathGO:00109422630.013
t cell homeostasisGO:004302930.013
plasma membrane organizationGO:00070091150.013
Human
intracellular mrna localizationGO:000829810.012
positive regulation of cellular amino acid metabolic processGO:004576430.012
negative regulation of proteolysisGO:00458611320.012
monosaccharide transportGO:0015749320.012
phospholipid biosynthetic processGO:0008654440.012
regionalizationGO:0003002290.012
hemostasisGO:0007599760.012
organ morphogenesisGO:00098871470.012
positive regulation of intracellular protein transportGO:0090316760.012
regulation of neuronal synaptic plasticityGO:004816810.012
negative regulation of cell morphogenesis involved in differentiationGO:0010771240.012
regulation of cyclic nucleotide metabolic processGO:0030799630.012
positive regulation of cellular catabolic processGO:00313312840.012
Human
positive regulation of phosphorylationGO:00423273940.012
regulation of stress activated mapk cascadeGO:0032872840.012
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.012
positive regulation of cyclic nucleotide metabolic processGO:0030801490.012
jnk cascadeGO:0007254800.012
epithelium migrationGO:00901321190.012
cardiovascular system developmentGO:00723582620.012
biological adhesionGO:00226103310.012
regulation of cyclic nucleotide biosynthetic processGO:0030802490.012
regulation of cell developmentGO:00602841610.012
generation of neuronsGO:00486991520.012
Fly
protein autophosphorylationGO:00467771230.012
negative regulation of protein phosphorylationGO:00019331400.012
regulation of leukocyte activationGO:00026941150.012
nucleotide catabolic processGO:00091664080.012
locomotory behaviorGO:000762610.012
regulation of actin polymerization or depolymerizationGO:0008064560.012
growthGO:00400072020.012
positive regulation of early endosome to late endosome transportGO:200064330.011
regulation of camp biosynthetic processGO:0030817450.011
regulation of purine nucleotide biosynthetic processGO:1900371500.011
regulation of gtp catabolic processGO:00331241800.011
regulation of establishment or maintenance of cell polarityGO:003287870.011
positive regulation of secretion by cellGO:19035321080.011
organic acid biosynthetic processGO:0016053970.011
positive regulation of nucleotide catabolic processGO:00308131850.011
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.011
rhythmic behaviorGO:000762220.011
cell cell signalingGO:00072671550.011
late endosome to vacuole transportGO:004532420.011
glycoprotein metabolic processGO:00091001100.011
positive regulation of cellular amine metabolic processGO:003324070.011
response to abiotic stimulusGO:00096283360.011
positive regulation of immune system processGO:00026842830.011
positive regulation of intracellular transportGO:00323881040.011
regulation of neurogenesisGO:0050767820.011
positive regulation of mapk cascadeGO:00434101900.011
determination of adult lifespanGO:000834020.011
negative regulation of cellular amino acid metabolic processGO:004576320.011
regulation of neurotransmitter secretionGO:004692830.011
negative regulation of immune system processGO:00026831360.011
regulation of synaptic vesicle transportGO:190280330.011
mitotic nuclear divisionGO:00070671190.011
early endosome to late endosome transportGO:0045022210.011
generation of precursor metabolites and energyGO:0006091680.011
oogenesisGO:004847720.010
positive regulation of stress activated mapk cascadeGO:0032874600.010
positive regulation of nucleoside metabolic processGO:00459791860.010
positive regulation of programmed cell deathGO:00430682490.010
response to cytokineGO:00340972320.010
regulation of cell activationGO:00508651250.010
positive regulation of cell migrationGO:00303351720.010
camp metabolic processGO:0046058610.010
regulation of secretionGO:00510461940.010
oxidation reduction processGO:00551143960.010
regulation of cysteine type endopeptidase activityGO:20001161270.010
negative regulation of nervous system developmentGO:0051961280.010

PLEKHF2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.466
cancerDOID:1621670.466
organ system cancerDOID:00506861640.277
connective tissue diseaseDOID:651090.052
bone development diseaseDOID:0080006550.052
musculoskeletal system diseaseDOID:172230.052
bone diseaseDOID:0080001880.052
immune system cancerDOID:0060083360.037
hematologic cancerDOID:2531360.023
leukemiaDOID:1240210.021
acute myeloid leukemiaDOID:9119170.021
myeloid leukemiaDOID:8692180.021
endocrine gland cancerDOID:170260.018
thyroid cancerDOID:1781130.018
papillary thyroid carcinomaDOID:396960.018
thyroid carcinomaDOID:3963130.018
nervous system diseaseDOID:8634310.011
sensory system diseaseDOID:00501552030.011