Homo sapiens

0 known processes

PPL

periplakin

(Aliases: KIAA0568,MGC134872)

PPL biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
keratinizationGO:003142420.980
tissue migrationGO:00901301190.877
neutrophil activation involved in immune responseGO:000228330.874
hair follicle morphogenesisGO:003106920.856
keratinocyte activationGO:003298010.845
ameboidal type cell migrationGO:00016671350.785
epithelial cell migrationGO:00106311190.727
neutrophil degranulationGO:004331230.719
positive regulation of endothelial cell migrationGO:0010595390.717
epithelium migrationGO:00901321190.693
defense response to bacteriumGO:0042742630.678
vasculature developmentGO:00019441810.671
endothelial cell migrationGO:0043542860.671
positive regulation of locomotionGO:00400171860.609
defense response to other organismGO:00985421290.604
exocytosisGO:0006887710.597
circulatory system developmentGO:00723592620.593
regulation of endothelial cell migrationGO:0010594670.591
neutrophil mediated immunityGO:000244640.585
regulation of cellular component movementGO:00512703340.557
positive regulation of epithelial cell migrationGO:0010634550.546
protein homooligomerizationGO:00512601000.545
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.517
biological adhesionGO:00226103310.471
positive regulation of cell migrationGO:00303351720.463
cardiovascular system developmentGO:00723582620.448
protein activation cascadeGO:0072376220.446
regulation of anatomical structure morphogenesisGO:00226032860.431
regulation of epithelial cell migrationGO:0010632930.423
vesicle mediated transportGO:00161923710.404
positive regulation of cell motilityGO:20001471770.399
transmembrane transportGO:00550853990.381
response to other organismGO:00517072610.357
response to bacteriumGO:00096171440.355
complement activation lectin pathwayGO:000186770.348
immune effector processGO:00022521590.343
defense responseGO:00069523150.339
epidermis morphogenesisGO:004873030.335
ion transmembrane transportGO:00342203380.325
blood vessel morphogenesisGO:00485141620.308
hair cycleGO:0042633280.301
regulation of vasculature developmentGO:1901342970.294
response to external biotic stimulusGO:00432072610.283
protein oligomerizationGO:00512591730.273
regulation of locomotionGO:00400123290.265
positive regulation of cellular component movementGO:00512721810.242
neutrophil activationGO:004211990.239
regulation of angiogenesisGO:0045765920.232
immune responseGO:00069553070.232
blood vessel developmentGO:00015681720.221
cell activationGO:00017752130.205
angiogenesisGO:00015251470.205
keratinocyte proliferationGO:0043616170.203
regulation of sequence specific dna binding transcription factor activityGO:00510902110.202
leukocyte activationGO:00453211640.195
skin developmentGO:0043588760.194
cell cell signalingGO:00072671550.194
regulation of cell motilityGO:20001452990.191
single organism cell adhesionGO:00986021790.181
positive regulation of angiogenesisGO:0045766510.173
granulocyte activationGO:0036230100.163
nucleoside catabolic processGO:00091644080.159
regenerationGO:003109940.150
synaptic transmissionGO:0007268610.149
tissue regenerationGO:004224630.145
organ morphogenesisGO:00098871470.145
cell adhesionGO:00071553250.132
leukocyte mediated immunityGO:0002443590.121
rho protein signal transductionGO:0007266260.116
purine ribonucleoside catabolic processGO:00461303980.111
keratinocyte differentiationGO:0030216360.109
anatomical structure formation involved in morphogenesisGO:00486462840.109
response to biotic stimulusGO:00096072760.104
regulation of membrane potentialGO:0042391950.104
innate immune responseGO:00450871780.101
cellular amino acid metabolic processGO:00065201160.101
myeloid leukocyte activationGO:0002274340.094
amine metabolic processGO:0009308440.094
ribonucleotide catabolic processGO:00092614050.094
nucleotide catabolic processGO:00091664080.093
retina homeostasisGO:0001895420.092
regulation of cellular ketone metabolic processGO:0010565500.087
membrane organizationGO:00610242920.085
intermediate filament organizationGO:0045109100.083
regulated secretory pathwayGO:0045055200.081
regulation of cellular amine metabolic processGO:0033238110.080
actin filament based movementGO:0030048170.079
purine nucleoside triphosphate catabolic processGO:00091463920.077
cell activation involved in immune responseGO:0002263300.075
secretion by cellGO:00329402260.074
epidermis developmentGO:0008544590.074
regulation of cell migrationGO:00303342890.074
secretionGO:00469032540.073
post embryonic developmentGO:000979120.073
leukocyte activation involved in immune responseGO:0002366300.073
cellular ketone metabolic processGO:0042180800.068
cellular lipid metabolic processGO:00442553030.064
epithelial cell differentiationGO:00308551410.061
cell developmentGO:00484683280.061
positive regulation of cellular amine metabolic processGO:003324070.060
cellular amine metabolic processGO:0044106410.058
regulation of cellular amino acid metabolic processGO:000652160.058
apoptotic signaling pathwayGO:00971902680.057
cytokine mediated signaling pathwayGO:00192211090.056
action potentialGO:0001508340.055
nucleoside phosphate catabolic processGO:19012924120.053
purine ribonucleoside triphosphate metabolic processGO:00092054110.052
leukocyte degranulationGO:0043299110.052
epidermal cell differentiationGO:0009913450.051
single organism membrane organizationGO:00448022680.051
epithelium developmentGO:00604292270.049
negative regulation of cellular protein metabolic processGO:00322693530.049
cardiac muscle cell contractionGO:008600340.048
purine ribonucleotide catabolic processGO:00091544040.047
ribonucleoside triphosphate metabolic processGO:00091994120.045
establishment of protein localization to membraneGO:00901501210.045
negative regulation of locomotionGO:00400131180.044
purine nucleotide catabolic processGO:00061954050.044
response to cytokineGO:00340972320.044
regulation of wnt signaling pathwayGO:00301111230.043
ribonucleoside triphosphate catabolic processGO:00092033910.043
plasma membrane organizationGO:00070091150.043
activation of immune responseGO:00022531140.043
single organism cellular localizationGO:19025803320.043
endocytosisGO:00068971590.042
humoral immune responseGO:0006959490.042
purine nucleoside triphosphate metabolic processGO:00091444120.041
response to lipidGO:00339932060.041
regulation of purine nucleotide metabolic processGO:19005422640.040
positive regulation of immune system processGO:00026842830.040
purine ribonucleoside triphosphate catabolic processGO:00092073910.040
striated muscle contractionGO:0006941520.040
negative regulation of cell motilityGO:20001461040.040
hair cycle processGO:0022405120.039
cell type specific apoptotic processGO:00972851250.038
positive regulation of programmed cell deathGO:00430682490.038
guanosine containing compound metabolic processGO:19010682440.038
embryonic placenta developmentGO:000189210.038
multicellular organismal agingGO:001025930.037
regulation of peptidase activityGO:00525471800.037
canonical wnt signaling pathwayGO:00600701160.037
phagocytosisGO:0006909420.036
negative regulation of cellular component movementGO:00512711060.036
tissue morphogenesisGO:0048729960.036
regulation of nucleotide metabolic processGO:00061402690.036
negative regulation of cell migrationGO:00303361020.035
lung alveolus developmentGO:004828640.035
ras protein signal transductionGO:0007265730.035
keratinocyte migrationGO:005154660.035
actin mediated cell contractionGO:0070252120.035
female gamete generationGO:000729220.035
regulation of proteolysisGO:00301622930.035
intermediate filament based processGO:0045103170.035
protein localization to plasma membraneGO:0072659930.034
muscle contractionGO:0006936730.034
response to organic cyclic compoundGO:00140702040.034
negative regulation of cellular component organizationGO:00511292350.033
negative regulation of protein metabolic processGO:00512483910.033
oogenesisGO:004847720.033
anatomical structure homeostasisGO:00602491000.033
positive regulation of hydrolase activityGO:00513453310.033
regulation of gtp catabolic processGO:00331241800.033
response to oxygen containing compoundGO:19017003690.033
negative regulation of axon extensionGO:003051720.032
lens development in camera type eyeGO:000208820.032
post embryonic organ developmentGO:004856910.032
neuromuscular junction developmentGO:000752830.032
regulation of nucleotide catabolic processGO:00308112050.032
positive regulation of cellular amino acid metabolic processGO:004576430.032
inorganic ion transmembrane transportGO:00986602310.031
positive regulation of mapk cascadeGO:00434101900.031
purine nucleoside catabolic processGO:00061523980.031
matingGO:000761810.030
regulation of ras protein signal transductionGO:00465781550.030
determination of adult lifespanGO:000834020.030
growthGO:00400072020.030
inorganic cation transmembrane transportGO:00986621940.030
regulation of nucleoside metabolic processGO:00091182090.030
golgi vesicle transportGO:0048193800.030
complement activationGO:0006956190.029
positive regulation of apoptotic processGO:00430652460.029
blastocyst developmentGO:000182430.029
cell morphogenesisGO:00009022960.029
negative regulation of cell proliferationGO:00082852280.028
positive regulation of cellular component organizationGO:00511303760.028
cell junction assemblyGO:0034329670.028
blastocyst formationGO:000182530.028
somatic stem cell maintenanceGO:003501940.028
lipid biosynthetic processGO:00086101770.028
response to abiotic stimulusGO:00096283360.028
glial cell migrationGO:000834740.028
mesendoderm developmentGO:004838210.028
myeloid leukocyte mediated immunityGO:0002444100.028
multicellular organismal signalingGO:0035637340.028
positive regulation of purine nucleotide catabolic processGO:00331231850.027
endodermal cell fate commitmentGO:000171140.027
small molecule biosynthetic processGO:00442831570.027
mitotic cell cycleGO:00002783260.027
regulation of immune responseGO:00507762010.027
regulation of protein kinase activityGO:00458592890.027
purine ribonucleoside metabolic processGO:00461284370.027
microtubule cytoskeleton organizationGO:00002261760.026
skin morphogenesisGO:004358960.026
regulation of endopeptidase activityGO:00525481700.026
wound healingGO:00420601150.026
ribonucleoside catabolic processGO:00424544060.026
small gtpase mediated signal transductionGO:0007264780.026
nerve developmentGO:002167540.026
cytoplasmic transportGO:00164823790.025
cellular response to cytokine stimulusGO:00713451810.025
trachea developmentGO:006043810.025
anterior posterior axis specificationGO:000994820.025
multicellular organismal homeostasisGO:0048871670.025
regulation of cytoskeleton organizationGO:00514931770.024
negative regulation of cellular amino acid metabolic processGO:004576320.024
peptidyl tyrosine phosphorylationGO:00181081700.024
protein maturationGO:00516042330.024
regulation of cellular response to stressGO:00801352440.024
positive regulation of immune responseGO:00507781590.024
regulation of actin filament based processGO:00329701410.024
glycosyl compound catabolic processGO:19016584130.023
positive regulation of cell proliferationGO:00082843010.023
enzyme linked receptor protein signaling pathwayGO:00071673030.023
positive regulation of cell deathGO:00109422630.023
cellular response to oxygen containing compoundGO:19017012760.023
negative regulation of organelle organizationGO:00106391260.023
cell divisionGO:00513011680.023
negative regulation of smoothened signaling pathwayGO:004587930.023
guanosine containing compound catabolic processGO:19010692390.023
regulation of axon guidanceGO:190266730.023
gtp metabolic processGO:00460392390.022
cellular response to dna damage stimulusGO:00069743790.022
positive regulation of nucleotide metabolic processGO:00459812300.022
regulation of glial cell differentiationGO:004568530.022
regulation of neurotrophin trk receptor signaling pathwayGO:005138620.022
response to woundingGO:00096111680.022
molting cycle processGO:0022404120.022
mapk cascadeGO:00001652880.022
catagenGO:004263730.022
epithelial cell fate commitmentGO:007214830.022
monocarboxylic acid metabolic processGO:00327871850.022
regulation of dna metabolic processGO:00510521530.022
lipid metabolic processGO:00066293810.022
cellular component morphogenesisGO:00329893140.022
cardiac chamber morphogenesisGO:0003206260.022
cellular response to endogenous stimulusGO:00714953360.022
negative regulation of catalytic activityGO:00430863350.022
negative regulation of cellular amine metabolic processGO:003323930.021
hair follicle developmentGO:0001942110.021
chemical homeostasisGO:00488783060.021
positive regulation of transportGO:00510503360.021
engulfment of apoptotic cellGO:004365220.021
negative regulation of multicellular organismal processGO:00512413170.021
actin filament organizationGO:00070151280.021
endomembrane system organizationGO:00102561960.021
morphogenesis of an epitheliumGO:0002009600.021
protein ubiquitinationGO:00165673140.021
myeloid cell activation involved in immune responseGO:0002275100.021
response to hormoneGO:00097251750.021
positive regulation of purine nucleotide metabolic processGO:19005442270.021
muscle cell developmentGO:0055001290.020
cellular macromolecule catabolic processGO:00442653800.020
single organismal cell cell adhesionGO:00163371480.020
organic hydroxy compound metabolic processGO:19016151470.020
taxisGO:00423301570.020
reactive nitrogen species metabolic processGO:200105730.020
embryonic morphogenesisGO:0048598850.020
actomyosin structure organizationGO:0031032590.020
response to axon injuryGO:004867810.020
microtubule based processGO:00070172100.020
astrocyte differentiationGO:004870840.020
regulation of gtpase activityGO:00430871800.020
locomotory behaviorGO:000762610.020
morphogenesis of a polarized epitheliumGO:000173830.020
regulation of establishment of protein localizationGO:00702012420.020
segmentationGO:003528240.020
cellular protein complex assemblyGO:00436231880.020
regulation of kinase activityGO:00435493140.020
digestive system developmentGO:0055123750.020
organic acid biosynthetic processGO:0016053970.019
oocyte developmentGO:004859910.019
heart morphogenesisGO:0003007480.019
axon regenerationGO:003110310.019
post golgi vesicle mediated transportGO:0006892360.019
organophosphate catabolic processGO:00464344300.019
negative regulation of cell deathGO:00605483450.019
positive regulation of cell differentiationGO:00455972110.019
regulation of protein transportGO:00512232130.019
negative regulation of catagenGO:005179610.019
sex determinationGO:000753030.019
regulation of protein modification by small protein conjugation or removalGO:19033201070.019
reactive oxygen species biosynthetic processGO:190340940.019
response to growth factorGO:00708482050.019
cellular response to abiotic stimulusGO:00712141170.019
cellular response to nitrogen compoundGO:19016991440.019
protein modification by small protein conjugationGO:00324463420.019
cellular component disassemblyGO:0022411920.018
positive regulation of phosphorylationGO:00423273940.018
negative regulation of phosphate metabolic processGO:00459362670.018
regulation of protein complex assemblyGO:00432541470.018
memoryGO:000761330.018
actin filament based processGO:00300292240.018
cell fate determinationGO:000170930.018
regulation of cellular component biogenesisGO:00440872810.018
positive regulation of ras gtpase activityGO:00323201170.018
regulation of cell morphogenesisGO:00226041530.018
muscle system processGO:0003012810.018
embryonic epithelial tube formationGO:000183840.018
purine containing compound catabolic processGO:00725234110.018
blastoderm segmentationGO:000735020.018
lens morphogenesis in camera type eyeGO:000208920.018
positive regulation of cellular catabolic processGO:00313312840.018
neuron projection developmentGO:00311751060.018
positive regulation of protein kinase activityGO:00458601900.018
negative regulation of hydrolase activityGO:00513461820.017
oocyte differentiationGO:000999420.017
dephosphorylationGO:00163112090.017
monocarboxylic acid biosynthetic processGO:0072330670.017
regulation of i kappab kinase nf kappab signalingGO:00431221620.017
regulation of purine nucleotide catabolic processGO:00331212050.017
actin cytoskeleton organizationGO:00300362070.017
neuron projection regenerationGO:003110210.017
establishment or maintenance of bipolar cell polarityGO:006124520.017
compound eye developmentGO:004874910.017
negative regulation of transcription initiation from rna polymerase ii promoterGO:006063330.017
melanin metabolic processGO:000658210.017
nervous system developmentGO:00073992930.017
posttranscriptional regulation of gene expressionGO:00106082130.017
endothelial cell proliferationGO:0001935650.017
transmission of nerve impulseGO:0019226110.017
negative regulation of neurotrophin trk receptor signaling pathwayGO:005138720.017
positive regulation of apoptotic signaling pathwayGO:2001235700.017
organelle assemblyGO:00709251760.017
neuroblast proliferationGO:000740540.017
intermediate filament cytoskeleton organizationGO:0045104170.017
chemotaxisGO:00069351570.016
protein processingGO:00164852260.016
regulation of cell cycleGO:00517263930.016
negative regulation of protein maturationGO:19033181420.016
morphogenesis of embryonic epitheliumGO:001633140.016
neurogenesisGO:00220081690.016
striated muscle cell differentiationGO:0051146430.016
neural tube formationGO:000184130.016
negative regulation of cell cycleGO:00457861930.016
atp metabolic processGO:00460341760.016
nucleoside monophosphate metabolic processGO:00091231910.016
signal transduction by phosphorylationGO:00230142970.016
agingGO:0007568660.016
positive regulation of reactive oxygen species biosynthetic processGO:190342820.016
chordate embryonic developmentGO:0043009340.016
response to radiationGO:00093141510.016
negative regulation of phosphorus metabolic processGO:00105632670.016
cell substrate adhesionGO:00315891320.015
regulation of response to external stimulusGO:00321012220.015
regulation of heart rateGO:0002027380.015
negative regulation of protein modification processGO:00314002000.015
positive regulation of cellular component biogenesisGO:00440891580.015
positive regulation of synaptic transmissionGO:005080640.015
muscle cell differentiationGO:0042692630.015
cellular response to tumor necrosis factorGO:0071356630.015
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.015
regulation of mapk cascadeGO:00434082620.015
photoreceptor cell differentiationGO:004653020.015
negative regulation of protein phosphorylationGO:00019331400.015
intermediate filament bundle assemblyGO:004511050.015
extrinsic apoptotic signaling pathwayGO:00971911190.015
regulation of cytokine productionGO:00018172320.015
regulation of protein ubiquitinationGO:0031396950.015
organophosphate biosynthetic processGO:00904071630.015
cellular macromolecular complex assemblyGO:00346223240.015
regulation of epithelial cell proliferationGO:00506781130.015
lipid transportGO:0006869900.015
positive regulation of transferase activityGO:00513472270.015
cell matrix adhesionGO:0007160850.015
inner ear morphogenesisGO:004247240.015
negative regulation of intracellular signal transductionGO:19025321830.014
carboxylic acid biosynthetic processGO:0046394970.014
regulation of cell adhesionGO:00301551660.014
regulation of synaptic plasticityGO:004816730.014
pituitary gland developmentGO:002198320.014
cellular response to organic cyclic compoundGO:00714071270.014
primary neural tube formationGO:001402030.014
cellular homeostasisGO:00197251960.014
regulation of protein catabolic processGO:00421761550.014
cellular response to growth factor stimulusGO:00713631970.014
oxidation reduction processGO:00551143960.014
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:190204330.014
response to fungusGO:000962040.014
muscle structure developmentGO:0061061980.014
histone modificationGO:00165702510.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
positive regulation of cell cycle processGO:00900681060.014
motor neuron axon guidanceGO:000804520.014
positive regulation of developmental processGO:00510943140.014
heart valve formationGO:000318820.014
spermatid differentiationGO:004851540.014
anterior posterior axis specification embryoGO:000859520.014
basement membrane organizationGO:007171130.014
cellular response to glucocorticoid stimulusGO:007138540.014
positive regulation of keratinocyte proliferationGO:001083840.014
regulation of astrocyte differentiationGO:004871030.014
positive regulation of organelle organizationGO:00106381950.014
anion transportGO:00068201610.014
cell projection assemblyGO:00300311260.014
regulation of metalloenzyme activityGO:004855230.014
regulation of protein processingGO:00706131500.014
negative regulation of proteolysisGO:00458611320.014
negative regulation of developmental processGO:00510932470.014
lymphocyte homeostasisGO:000226040.013
cell projection organizationGO:00300302520.013
cation transmembrane transportGO:00986552380.013
long term memoryGO:000761620.013
cellular response to radiationGO:0071478650.013
ossificationGO:00015031210.013
positive regulation of gtpase activityGO:00435471660.013
cytokinesisGO:0000910960.013
regulation of transferase activityGO:00513383550.013
cellular protein catabolic processGO:00442572610.013
nucleoside monophosphate catabolic processGO:00091251590.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
negative regulation of protein processingGO:00109551420.013
regulation of protein localizationGO:00328802960.013
embryonic camera type eye developmentGO:003107620.013
positive regulation of rho gtpase activityGO:0032321560.013
digestive tract developmentGO:0048565750.013
gastrulation with mouth forming secondGO:000170210.013
somatic muscle developmentGO:000752510.013
cellular component assembly involved in morphogenesisGO:0010927730.013
wnt signaling pathwayGO:00160551560.013
atrioventricular valve developmentGO:000317130.013
regulation of lipase activityGO:0060191370.013
reactive oxygen species metabolic processGO:0072593750.013
tripartite regional subdivisionGO:000735120.013
epithelial cell proliferationGO:00506731280.013
desmosome assemblyGO:000215940.013
negative regulation of transportGO:00510511760.013
system processGO:00030083490.013
divalent metal ion transportGO:00708381520.013
regulation of apoptotic signaling pathwayGO:20012331750.013
actin filament bundle organizationGO:0061572540.013
establishment of planar polarityGO:000173630.013
glycerolipid metabolic processGO:00464861070.013
organic hydroxy compound biosynthetic processGO:1901617710.012
regulation of protein maturationGO:19033171500.012
regulation of axon extension involved in axon guidanceGO:004884120.012
positive regulation of reactive oxygen species metabolic processGO:2000379240.012
response to drugGO:0042493810.012
sequestering of metal ionGO:0051238240.012
regulation of cellular component sizeGO:0032535820.012
positive regulation of catabolic processGO:00098963100.012
second messenger mediated signalingGO:0019932780.012
regulation of defense responseGO:00313471540.012
regulation of protein stabilityGO:0031647870.012
fatty acid metabolic processGO:00066311150.012
regulation of neural precursor cell proliferationGO:200017740.012
sequestering of calcium ionGO:0051208170.012
embryonic forelimb morphogenesisGO:003511540.012
startle responseGO:000196430.012
positive regulation of dendrite morphogenesisGO:005077530.012
regulation of endothelial cell proliferationGO:0001936560.012
neurological system processGO:00508771630.012
gtp catabolic processGO:00061842370.012
rhythmic behaviorGO:000762220.012
regulation of cardiac muscle contractionGO:0055117330.012
peptidyl tyrosine modificationGO:00182121700.012
regulation of peptidyl tyrosine phosphorylationGO:00507301080.012
generation of neuronsGO:00486991520.012
regulation of ion transportGO:00432691890.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
protein localization to organelleGO:00333652800.012
osteoblast differentiationGO:0001649920.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
cell morphogenesis involved in differentiationGO:00009041440.012

PPL disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:00506861640.033
cancerDOID:1621670.033
disease of cellular proliferationDOID:145661740.033
musculoskeletal system diseaseDOID:172230.027
eye and adnexa diseaseDOID:14921500.023
nervous system diseaseDOID:8634310.023
eye diseaseDOID:56141490.023
sensory system diseaseDOID:00501552030.023
gastrointestinal system cancerDOID:3119520.022
inherited metabolic disorderDOID:6552420.022
disease of metabolismDOID:00146672950.022
central nervous system diseaseDOID:3311860.017
connective tissue diseaseDOID:651090.014
bone diseaseDOID:0080001880.014
bone development diseaseDOID:0080006550.014
reproductive organ cancerDOID:193230.013
cardiovascular system diseaseDOID:12871060.012
osteochondrodysplasiaDOID:2256350.012
integumentary system diseaseDOID:16430.012