Homo sapiens

0 known processes

APEX2

APEX nuclease (apurinic/apyrimidinic endonuclease) 2

(Aliases: APE2,APEXL2,XTH2)

APEX2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069743790.066
Yeast
cytoplasmic transportGO:00164823790.057
vesicle mediated transportGO:00161923710.056
endomembrane system organizationGO:00102561960.046
membrane organizationGO:00610242920.044
organophosphate catabolic processGO:00464344300.042
purine containing compound catabolic processGO:00725234110.041
single organism membrane organizationGO:00448022680.040
hematopoietic or lymphoid organ developmentGO:00485341860.039
dna repairGO:00062811980.039
Yeast
post embryonic developmentGO:000979120.038
ras protein signal transductionGO:0007265730.036
cation transportGO:00068123310.036
nucleoside triphosphate catabolic processGO:00091433940.035
glycosyl compound catabolic processGO:19016584130.035
purine ribonucleoside catabolic processGO:00461303980.035
purine nucleoside catabolic processGO:00061523980.031
regulation of cell cycleGO:00517263930.030
response to abiotic stimulusGO:00096283360.030
double strand break repairGO:00063021010.029
amine metabolic processGO:0009308440.029
dna conformation changeGO:00711031130.028
mitotic cell cycleGO:00002783260.028
protein ubiquitinationGO:00165673140.028
positive regulation of catabolic processGO:00098963100.028
ribonucleoside triphosphate catabolic processGO:00092033910.027
nucleoside catabolic processGO:00091644080.027
lipid metabolic processGO:00066293810.027
purine nucleoside triphosphate catabolic processGO:00091463920.026
positive regulation of cellular catabolic processGO:00313312840.026
female gamete generationGO:000729220.026
cellular amino acid metabolic processGO:00065201160.026
negative regulation of phosphate metabolic processGO:00459362670.026
purine ribonucleoside triphosphate catabolic processGO:00092073910.026
oocyte differentiationGO:000999420.025
nucleoside triphosphate metabolic processGO:00091414220.025
nucleoside phosphate catabolic processGO:19012924120.025
protein localization to organelleGO:00333652800.025
determination of adult lifespanGO:000834020.024
mitotic cell cycle processGO:19030472860.024
single organism cellular localizationGO:19025803320.024
negative regulation of cell cycleGO:00457861930.024
ribonucleoside catabolic processGO:00424544060.023
negative regulation of cell deathGO:00605483450.023
cellular amine metabolic processGO:0044106410.023
regulation of establishment of protein localizationGO:00702012420.023
interspecies interaction between organismsGO:00444191560.023
system processGO:00030083490.023
purine ribonucleotide catabolic processGO:00091544040.023
i kappab kinase nf kappab signalingGO:00072491660.023
nucleotide catabolic processGO:00091664080.022
locomotory behaviorGO:000762610.022
negative regulation of phosphorus metabolic processGO:00105632670.021
response to other organismGO:00517072610.021
cellular lipid metabolic processGO:00442553030.021
multicellular organismal agingGO:001025930.021
protein modification by small protein conjugationGO:00324463420.021
purine nucleotide catabolic processGO:00061954050.021
oogenesisGO:004847720.021
regulation of nucleoside metabolic processGO:00091182090.021
nervous system developmentGO:00073992930.021
positive regulation of cellular amino acid metabolic processGO:004576430.021
regulation of intracellular transportGO:00323861950.021
protein catabolic processGO:00301633250.020
actin filament based processGO:00300292240.020
negative regulation of apoptotic processGO:00430663160.020
guanosine containing compound metabolic processGO:19010682440.020
lipid biosynthetic processGO:00086101770.020
small gtpase mediated signal transductionGO:0007264780.020
symbiosis encompassing mutualism through parasitismGO:00444031560.020
regulation of proteolysisGO:00301622930.020
ribonucleotide catabolic processGO:00092614050.020
defense responseGO:00069523150.020
regulation of protein localizationGO:00328802960.020
immune responseGO:00069553070.020
response to oxygen containing compoundGO:19017003690.020
immune effector processGO:00022521590.019
secretionGO:00469032540.019
striated muscle myosin thick filament assemblyGO:007168820.019
purine ribonucleoside triphosphate metabolic processGO:00092054110.019
neurogenesisGO:00220081690.019
carbohydrate derivative biosynthetic processGO:19011372070.019
negative regulation of transportGO:00510511760.019
ribonucleoside triphosphate metabolic processGO:00091994120.019
regulation of cellular amine metabolic processGO:0033238110.019
viral processGO:00160321460.019
cellular component morphogenesisGO:00329893140.019
purine nucleoside triphosphate metabolic processGO:00091444120.019
transmembrane transportGO:00550853990.018
regulation of immune effector processGO:0002697910.018
positive regulation of proteolysisGO:00458621420.018
dna replicationGO:00062601160.018
guanosine containing compound catabolic processGO:19010692390.018
organelle assemblyGO:00709251760.018
negative regulation of cellular protein metabolic processGO:00322693530.018
response to external biotic stimulusGO:00432072610.018
microtubule based processGO:00070172100.018
cell developmentGO:00484683280.018
chemical homeostasisGO:00488783060.018
regulation of ras protein signal transductionGO:00465781550.018
ion homeostasisGO:00508012300.017
metal ion transportGO:00300012720.017
regulation of immune responseGO:00507762010.017
positive regulation of hydrolase activityGO:00513453310.017
oocyte developmentGO:004859910.017
regulation of cellular amino acid metabolic processGO:000652160.017
dephosphorylationGO:00163112090.017
regulation of cell cycle phase transitionGO:19019871260.017
positive regulation of cell proliferationGO:00082843010.017
organophosphate biosynthetic processGO:00904071630.017
regulation of mitotic cell cycleGO:00073461890.017
mitotic cell cycle phase transitionGO:00447721620.017
regulation of transferase activityGO:00513383550.017
regulation of small gtpase mediated signal transductionGO:00510561560.017
negative regulation of protein metabolic processGO:00512483910.016
anatomical structure formation involved in morphogenesisGO:00486462840.016
cellular macromolecule catabolic processGO:00442653800.016
Yeast
response to biotic stimulusGO:00096072760.016
nitrogen compound transportGO:00717051910.016
positive regulation of cell deathGO:00109422630.016
regulation of cell cycle processGO:00105642660.016
gtp catabolic processGO:00061842370.016
nucleic acid phosphodiester bond hydrolysisGO:00903051020.015
Yeast
thymus developmentGO:004853830.015
regulation of purine nucleotide metabolic processGO:19005422640.015
organic acid biosynthetic processGO:0016053970.015
myosin filament assemblyGO:003103420.015
endosomal transportGO:00161971290.015
cell divisionGO:00513011680.015
anion transportGO:00068201610.015
multi organism cellular processGO:00447641560.015
establishment of protein localization to organelleGO:00725941720.015
dna recombinationGO:0006310770.015
posttranscriptional regulation of gene expressionGO:00106082130.015
gtp metabolic processGO:00460392390.015
membrane lipid metabolic processGO:0006643530.015
regulation of nucleotide metabolic processGO:00061402690.015
regulation of i kappab kinase nf kappab signalingGO:00431221620.015
viral life cycleGO:00190581320.015
positive regulation of cellular amine metabolic processGO:003324070.015
ion transmembrane transportGO:00342203380.015
regulation of kinase activityGO:00435493140.015
cellular protein complex assemblyGO:00436231880.015
negative regulation of catalytic activityGO:00430863350.014
positive regulation of gtp catabolic processGO:00331261660.014
regulation of cellular ketone metabolic processGO:0010565500.014
negative regulation of cell proliferationGO:00082852280.014
regulation of nucleotide catabolic processGO:00308112050.014
intracellular protein transportGO:00068862700.014
regulation of purine nucleotide catabolic processGO:00331212050.014
enzyme linked receptor protein signaling pathwayGO:00071673030.014
spermatid differentiationGO:004851540.014
cellular protein catabolic processGO:00442572610.014
small molecule biosynthetic processGO:00442831570.014
negative regulation of programmed cell deathGO:00430693210.014
carbohydrate metabolic processGO:00059752070.014
regulation of cell differentiationGO:00455953930.014
response to virusGO:00096151260.013
secretion by cellGO:00329402260.013
cell morphogenesisGO:00009022960.013
protein acylationGO:00435431380.013
modification dependent protein catabolic processGO:00199412090.013
positive regulation of transportGO:00510503360.013
regulation of cellular response to stressGO:00801352440.013
nuclear transportGO:00511691790.013
regulation of ras gtpase activityGO:00323181280.013
proteasomal protein catabolic processGO:00104981760.013
protein localization to membraneGO:00726571600.013
regulation of gtp catabolic processGO:00331241800.013
regulation of mitotic cell cycle phase transitionGO:19019901180.013
segmentationGO:003528240.013
spermatid developmentGO:000728640.013
myosin filament organizationGO:003103320.013
negative regulation of cellular component organizationGO:00511292350.013
regulation of protein kinase activityGO:00458592890.013
response to cytokineGO:00340972320.013
neuromuscular junction developmentGO:000752830.012
response to fungusGO:000962040.012
cell projection organizationGO:00300302520.012
endocytosisGO:00068971590.012
positive regulation of programmed cell deathGO:00430682490.012
carboxylic acid biosynthetic processGO:0046394970.012
positive regulation of immune system processGO:00026842830.012
regulation of dna metabolic processGO:00510521530.012
defense response to other organismGO:00985421290.012
blastoderm segmentationGO:000735020.012
dna packagingGO:0006323770.012
regulation of protein catabolic processGO:00421761550.012
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
organic anion transportGO:00157111030.012
cell cycle checkpointGO:00000751170.012
cellular response to cytokine stimulusGO:00713451810.012
purine ribonucleoside metabolic processGO:00461284370.012
regulation of gtpase activityGO:00430871800.012
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.011
cellular homeostasisGO:00197251960.011
immune system developmentGO:00025201950.011
positive regulation of endopeptidase activityGO:0010950840.011
regulation of protein transportGO:00512232130.011
regulation of cytoplasmic transportGO:19036491490.011
regulation of peptidase activityGO:00525471800.011
regulation of leukocyte activationGO:00026941150.011
actin cytoskeleton organizationGO:00300362070.011
negative regulation of hydrolase activityGO:00513461820.011
phospholipid metabolic processGO:0006644990.011
rna processingGO:00063962550.011
positive regulation of cellular component organizationGO:00511303760.011
covalent chromatin modificationGO:00165692540.011
glycerolipid metabolic processGO:00464861070.011
positive regulation of purine nucleotide metabolic processGO:19005442270.011
innate immune responseGO:00450871780.011
positive regulation of purine nucleotide catabolic processGO:00331231850.011
positive regulation of nucleotide metabolic processGO:00459812300.011
cell activationGO:00017752130.011
protein localization to nucleusGO:00345041360.011
cell cycle phase transitionGO:00447701730.011
negative regulation of phosphorylationGO:00423261740.011
cell growthGO:00160491600.011
modification dependent macromolecule catabolic processGO:00436322120.011
chromosome segregationGO:00070591140.010
regulation of secretionGO:00510461940.010
regulation of t cell activationGO:0050863770.010
adult locomotory behaviorGO:000834410.010
hemopoiesisGO:00300971800.010
central nervous system developmentGO:00074171230.010
regulation of defense responseGO:00313471540.010
positive regulation of nucleotide catabolic processGO:00308131850.010
glycerophospholipid metabolic processGO:0006650840.010
negative regulation of protein kinase activityGO:0006469980.010
histone modificationGO:00165702510.010
regulation of vesicle mediated transportGO:00606271300.010

APEX2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.066
inherited metabolic disorderDOID:6552420.031
carbohydrate metabolic disorderDOID:2978550.015
central nervous system diseaseDOID:3311860.011
nervous system diseaseDOID:8634310.011
disease of cellular proliferationDOID:145661740.011
cancerDOID:1621670.011