Homo sapiens

42 known processes

XRN2

5'-3' exoribonuclease 2

XRN2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna processingGO:00063962550.455
Worm
ncrna metabolic processGO:00346601080.283
Worm
trna processingGO:0008033230.256
purine containing compound catabolic processGO:00725234110.244
intracellular mrna localizationGO:000829810.243
purine nucleotide catabolic processGO:00061954050.208
post embryonic developmentGO:000979120.204
Worm
viral processGO:00160321460.148
oogenesisGO:004847720.141
nucleoside phosphate catabolic processGO:19012924120.123
ribonucleoside catabolic processGO:00424544060.123
multicellular organismal agingGO:001025930.108
gtp metabolic processGO:00460392390.105
cellular component disassemblyGO:0022411920.104
organophosphate catabolic processGO:00464344300.100
purine ribonucleoside triphosphate metabolic processGO:00092054110.099
blastoderm segmentationGO:000735020.098
single organism cellular localizationGO:19025803320.097
nucleoside triphosphate catabolic processGO:00091433940.096
immune responseGO:00069553070.093
ncrna processingGO:0034470830.092
nuclear transportGO:00511691790.090
glycosyl compound catabolic processGO:19016584130.088
rna 3 end processingGO:0031123350.088
ribonucleoprotein complex subunit organizationGO:0071826810.088
determination of adult lifespanGO:000834020.088
interspecies interaction between organismsGO:00444191560.084
purine ribonucleotide catabolic processGO:00091544040.084
membrane organizationGO:00610242920.083
gtp catabolic processGO:00061842370.079
regulation of intracellular transportGO:00323861950.074
mitotic cell cycleGO:00002783260.072
guanosine containing compound metabolic processGO:19010682440.067
purine nucleoside catabolic processGO:00061523980.067
ribonucleoside triphosphate metabolic processGO:00091994120.067
intracellular protein transportGO:00068862700.065
cytoplasmic transportGO:00164823790.065
small gtpase mediated signal transductionGO:0007264780.061
rna localizationGO:0006403410.059
viral life cycleGO:00190581320.059
organophosphate biosynthetic processGO:00904071630.052
positive regulation of cellular component organizationGO:00511303760.050
nucleoside catabolic processGO:00091644080.050
female gamete generationGO:000729220.050
regulation of cell cycle processGO:00105642660.048
multi organism cellular processGO:00447641560.048
mitotic cell cycle processGO:19030472860.045
regulation of gtp catabolic processGO:00331241800.044
purine ribonucleoside catabolic processGO:00461303980.044
rna transportGO:0050658390.041
ribonucleotide catabolic processGO:00092614050.041
locomotory behaviorGO:000762610.041
segmentationGO:003528240.041
nuclear exportGO:0051168690.039
nucleoside triphosphate metabolic processGO:00091414220.039
coenzyme metabolic processGO:0006732650.039
organelle assemblyGO:00709251760.037
positive regulation of catabolic processGO:00098963100.037
vesicle mediated transportGO:00161923710.037
negative regulation of multi organism processGO:0043901920.037
tripartite regional subdivisionGO:000735120.037
purine ribonucleoside metabolic processGO:00461284370.036
cell morphogenesisGO:00009022960.036
regulation of bindingGO:00510981110.035
oocyte developmentGO:004859910.035
mrna export from nucleusGO:0006406290.035
mrna 3 end processingGO:0031124240.035
positive regulation of cellular catabolic processGO:00313312840.035
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.035
nervous system developmentGO:00073992930.035
system processGO:00030083490.034
positive regulation of purine nucleotide catabolic processGO:00331231850.034
regulation of ras protein signal transductionGO:00465781550.034
establishment or maintenance of cytoskeleton polarityGO:003095230.034
anterior posterior axis specification embryoGO:000859520.034
regulation of nucleotide metabolic processGO:00061402690.033
rna modificationGO:0009451270.033
purine ribonucleoside triphosphate catabolic processGO:00092073910.033
ribonucleoprotein complex assemblyGO:0022618780.033
mrna metabolic processGO:00160711750.033
nucleic acid phosphodiester bond hydrolysisGO:00903051020.032
negative regulation of cell deathGO:00605483450.032
guanosine containing compound catabolic processGO:19010692390.032
cellular macromolecule catabolic processGO:00442653800.032
regulation of small gtpase mediated signal transductionGO:00510561560.031
purine nucleoside triphosphate metabolic processGO:00091444120.031
regulation of viral processGO:00507921030.031
negative regulation of viral processGO:0048525660.031
cofactor metabolic processGO:0051186870.031
nuclear importGO:00511701060.030
regulation of rab protein signal transductionGO:0032483390.030
positive regulation of intracellular transportGO:00323881040.030
regulation of anatomical structure morphogenesisGO:00226032860.030
regulation of meiotic cell cycleGO:005144540.029
rab protein signal transductionGO:003248240.029
regulation of purine nucleotide catabolic processGO:00331212050.029
mrna transportGO:0051028300.029
purine nucleoside monophosphate catabolic processGO:00091281580.029
purine nucleoside triphosphate catabolic processGO:00091463920.029
innate immune responseGO:00450871780.028
cellular macromolecular complex assemblyGO:00346223240.028
positive regulation of hydrolase activityGO:00513453310.028
lipid metabolic processGO:00066293810.028
defense responseGO:00069523150.028
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.028
negative regulation of developmental processGO:00510932470.027
cation homeostasisGO:00550801890.027
oocyte differentiationGO:000999420.026
mrna processingGO:00063971330.026
positive regulation of apoptotic processGO:00430652460.025
regulation of nucleotide catabolic processGO:00308112050.025
anterior posterior axis specificationGO:000994820.025
actin filament based processGO:00300292240.025
regulation of establishment of protein localizationGO:00702012420.025
protein importGO:00170381300.024
rna export from nucleusGO:0006405330.024
regulation of multi organism processGO:00439001570.024
ras protein signal transductionGO:0007265730.024
negative regulation of multicellular organismal processGO:00512413170.024
regulation of protein catabolic processGO:00421761550.024
regulation of nucleoside metabolic processGO:00091182090.024
positive regulation of gtp catabolic processGO:00331261660.023
establishment of protein localization to membraneGO:00901501210.023
regulation of protein transportGO:00512232130.023
nucleotide catabolic processGO:00091664080.023
cell growthGO:00160491600.023
negative regulation of phosphorus metabolic processGO:00105632670.023
regulation of cytoplasmic transportGO:19036491490.022
cellular component morphogenesisGO:00329893140.022
protein targeting to nucleusGO:00447441040.022
neuron projection developmentGO:00311751060.022
protein localization to nucleusGO:00345041360.022
establishment of rna localizationGO:0051236390.022
cell part morphogenesisGO:00329901370.022
organelle localizationGO:0051640840.022
regulation of cellular amino acid metabolic processGO:000652160.021
positive regulation of purine nucleotide metabolic processGO:19005442270.021
regulation of gtpase activityGO:00430871800.021
rna splicingGO:00083801310.021
regulation of meiosisGO:004002030.021
protein catabolic processGO:00301633250.021
snrna metabolic processGO:0016073150.021
positive regulation of nucleocytoplasmic transportGO:0046824540.021
nucleocytoplasmic transportGO:00069131760.021
nuclear transcribed mrna catabolic processGO:0000956480.021
regulation of protein targetingGO:1903533910.020
negative regulation of intracellular signal transductionGO:19025321830.020
regulation of apoptotic signaling pathwayGO:20012331750.020
agingGO:0007568660.020
cellular amine metabolic processGO:0044106410.020
hematopoietic or lymphoid organ developmentGO:00485341860.020
amine metabolic processGO:0009308440.020
immune effector processGO:00022521590.019
symbiosis encompassing mutualism through parasitismGO:00444031560.019
cell cycle phase transitionGO:00447701730.019
engulfment of apoptotic cellGO:004365220.019
negative regulation of catalytic activityGO:00430863350.019
regulation of cell cycle g1 s phase transitionGO:1902806420.019
histone mrna metabolic processGO:0008334130.019
regulation of cellular response to stressGO:00801352440.019
positive regulation of protein catabolic processGO:0045732750.019
rna catabolic processGO:0006401710.019
Worm
cell morphogenesis involved in differentiationGO:00009041440.019
regulation of cell cycleGO:00517263930.018
response to woundingGO:00096111680.018
single organism cell adhesionGO:00986021790.018
rna interferenceGO:001624640.018
cell projection organizationGO:00300302520.018
positive regulation of protein transportGO:00512221350.018
regulation of cellular component biogenesisGO:00440872810.018
mrna catabolic processGO:0006402560.018
growthGO:00400072020.018
dna geometric changeGO:0032392320.018
positive regulation of apoptotic signaling pathwayGO:2001235700.017
nitrogen compound transportGO:00717051910.017
positive regulation of cell cycle processGO:00900681060.017
organonitrogen compound biosynthetic processGO:19015662000.017
posttranscriptional regulation of gene expressionGO:00106082130.017
Worm
protein localization to organelleGO:00333652800.017
adult locomotory behaviorGO:000834410.017
response to biotic stimulusGO:00096072760.017
ribonucleoside triphosphate catabolic processGO:00092033910.017
positive regulation of cellular amino acid metabolic processGO:004576430.017
cytokine productionGO:00018162470.017
protein modification by small protein removalGO:0070646920.017
translationGO:00064121320.017
lipid localizationGO:00108761060.017
cation transportGO:00068123310.016
ribonucleoprotein complex biogenesisGO:00226131160.016
regulation of immune responseGO:00507762010.016
positive regulation of intracellular protein transportGO:0090316760.016
regulation of nucleocytoplasmic transportGO:0046822980.016
single organism nuclear importGO:19025931040.016
negative regulation of cellular component organizationGO:00511292350.016
multicellular organismal signalingGO:0035637340.016
apoptotic signaling pathwayGO:00971902680.016
translational initiationGO:0006413480.016
cell projection morphogenesisGO:00488581290.016
negative regulation of apoptotic processGO:00430663160.015
response to nitrogen compoundGO:19016981840.015
actin cytoskeleton organizationGO:00300362070.015
regulation of cellular amine metabolic processGO:0033238110.015
nuclear transcribed mrna catabolic process nonsense mediated decayGO:0000184230.015
cell developmentGO:00484683280.015
protein modification by small protein conjugationGO:00324463420.015
positive regulation of transportGO:00510503360.015
protein targetingGO:00066051870.015
biological adhesionGO:00226103310.015
positive regulation of cytoplasmic transportGO:1903651820.015
sleepGO:003043120.015
cofactor biosynthetic processGO:0051188310.015
ncrna 3 end processingGO:004362840.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
blastocyst developmentGO:000182430.014
negative regulation of programmed cell deathGO:00430693210.014
dna replicationGO:00062601160.014
negative regulation of growthGO:0045926970.014
microtubule based processGO:00070172100.014
cardiovascular system developmentGO:00723582620.014
cellular response to cytokine stimulusGO:00713451810.014
coenzyme biosynthetic processGO:0009108240.014
positive regulation of ras gtpase activityGO:00323201170.014
neurological system processGO:00508771630.014
positive regulation of cell proliferationGO:00082843010.014
wound healingGO:00420601150.014
nucleobase containing compound transportGO:0015931510.014
establishment of protein localization to organelleGO:00725941720.014
regenerationGO:003109940.014
regulation of ras gtpase activityGO:00323181280.013
blood vessel developmentGO:00015681720.013
metal ion homeostasisGO:00550651690.013
blood vessel morphogenesisGO:00485141620.013
negative regulation of mitotic cell cycleGO:00459301020.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.013
regulation of gene expression epigeneticGO:0040029730.013
Worm
cellular homeostasisGO:00197251960.013
meiosis iGO:000712740.013
generation of neuronsGO:00486991520.013
neuron developmentGO:00486661130.013
regulation of cytokine productionGO:00018172320.013
regulation of translationGO:0006417890.013
methylationGO:00322591060.013
regulation of protein localizationGO:00328802960.013
trna metabolic processGO:0006399350.012
regulation of cellular ketone metabolic processGO:0010565500.012
immune system developmentGO:00025201950.012
regulation of cell divisionGO:00513021160.012
rna polyadenylationGO:0043631140.012
cellular cation homeostasisGO:00300031630.012
positive regulation of protein complex assemblyGO:0031334860.012
response to cytokineGO:00340972320.012
cell cycle g1 s phase transitionGO:0044843800.012
regulation of membrane potentialGO:0042391950.012
cellular response to dna damage stimulusGO:00069743790.012
regulation of growthGO:00400081650.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
positive regulation of cell deathGO:00109422630.012
vasculature developmentGO:00019441810.012
response to extracellular stimulusGO:0009991850.012
wnt signaling pathwayGO:00160551560.012
ribonucleoprotein complex disassemblyGO:003298870.012
positive regulation of immune system processGO:00026842830.012
neuron differentiationGO:00301821380.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.012
melanin metabolic processGO:000658210.012
nucleoside monophosphate catabolic processGO:00091251590.012
g1 s transition of mitotic cell cycleGO:0000082780.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
regulation of vasculature developmentGO:1901342970.012
cation transmembrane transportGO:00986552380.012
tissue regenerationGO:004224630.011
microtubule cytoskeleton organizationGO:00002261760.011
enzyme linked receptor protein signaling pathwayGO:00071673030.011
inorganic cation transmembrane transportGO:00986621940.011
matingGO:000761810.011
motor neuron axon guidanceGO:000804520.011
positive regulation of cell differentiationGO:00455972110.011
neurogenesisGO:00220081690.011
negative regulation of canonical wnt signaling pathwayGO:0090090550.011
nucleoside monophosphate metabolic processGO:00091231910.011
cell adhesionGO:00071553250.011
regulation of cell cycle phase transitionGO:19019871260.011
multicellular organismal reproductive processGO:0048609400.011
positive regulation of mitotic cell cycleGO:0045931600.011
multi organism metabolic processGO:0044033410.011
anatomical structure formation involved in morphogenesisGO:00486462840.011
regulation of body fluid levelsGO:0050878990.011
regulation of mitotic cell cycleGO:00073461890.010
endomembrane system organizationGO:00102561960.010
positive regulation of organelle organizationGO:00106381950.010
single organism membrane organizationGO:00448022680.010
rho protein signal transductionGO:0007266260.010
circulatory system developmentGO:00723592620.010
dosage compensationGO:000754930.010
cellular metal ion homeostasisGO:00068751460.010
positive regulation of developmental processGO:00510943140.010

XRN2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.063
sensory system diseaseDOID:00501552030.027
nervous system diseaseDOID:8634310.027
eye and adnexa diseaseDOID:14921500.021
disease of mental healthDOID:150700.020
central nervous system diseaseDOID:3311860.017
brain diseaseDOID:936730.014
skin diseaseDOID:37330.012
integumentary system diseaseDOID:16430.012
neurodegenerative diseaseDOID:12891020.010