Homo sapiens

58 known processes

POLD1

polymerase (DNA directed), delta 1, catalytic subunit 125kDa

(Aliases: CDC2,POLD)

POLD1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna replicationGO:00062601160.964
cellular response to dna damage stimulusGO:00069743790.895
dna repairGO:00062811980.885
mitotic cell cycleGO:00002783260.706
negative regulation of cell cycleGO:00457861930.640
double strand break repairGO:00063021010.630
dna biosynthetic processGO:0071897400.549
base excision repairGO:0006284210.514
post embryonic developmentGO:000979120.511
Worm
microtubule based processGO:00070172100.470
nucleotide excision repairGO:0006289310.448
determination of adult lifespanGO:000834020.379
mitotic cell cycle phase transitionGO:00447721620.357
dna replication initiationGO:000627060.333
regulation of cell cycle processGO:00105642660.289
dna strand elongationGO:002261650.287
Yeast
cellular macromolecule catabolic processGO:00442653800.252
Yeast
meiosis iGO:000712740.226
dna dependent dna replicationGO:0006261440.208
Yeast Mouse Rat
cell cycle checkpointGO:00000751170.206
cell developmentGO:00484683280.203
cell cycle arrestGO:0007050710.196
microtubule cytoskeleton organizationGO:00002261760.193
response to uvGO:0009411730.183
negative regulation of mitotic cell cycleGO:00459301020.182
regulation of cell cycleGO:00517263930.177
translesion synthesisGO:001998580.155
embryo developmentGO:00097901230.146
Worm
g1 s transition of mitotic cell cycleGO:0000082780.140
non recombinational repairGO:0000726140.136
mitotic cell cycle processGO:19030472860.133
mitotic cell cycle checkpointGO:0007093680.128
dna damage checkpointGO:0000077680.127
mitotic dna damage checkpointGO:0044773280.114
cell cycle phase transitionGO:00447701730.113
postreplication repairGO:0006301120.112
chromosome segregationGO:00070591140.111
positive regulation of cell cycle processGO:00900681060.102
cell cycle g2 m phase transitionGO:0044839430.101
single organism reproductive processGO:0044702980.100
dna conformation changeGO:00711031130.099
cell cycle g1 s phase transitionGO:0044843800.095
regulation of cell cycle phase transitionGO:19019871260.093
reproductive processGO:00224141060.092
mitotic dna integrity checkpointGO:0044774300.088
negative regulation of cell cycle processGO:00109481210.086
negative regulation of cell deathGO:00605483450.086
regulation of dna metabolic processGO:00510521530.083
multicellular organismal agingGO:001025930.078
spindle organizationGO:0007051530.074
organophosphate catabolic processGO:00464344300.073
vesicle mediated transportGO:00161923710.073
Worm
negative regulation of mitotic cell cycle phase transitionGO:1901991850.073
organelle fissionGO:00482851490.072
modification dependent macromolecule catabolic processGO:00436322120.071
developmental process involved in reproductionGO:0003006660.071
regulation of mitotic cell cycle phase transitionGO:19019901180.070
regulation of dna replicationGO:0006275680.069
response to abiotic stimulusGO:00096283360.069
gene silencingGO:0016458490.064
organelle assemblyGO:00709251760.062
mitotic sister chromatid cohesionGO:0007064120.062
purine ribonucleoside triphosphate metabolic processGO:00092054110.061
digestive tract developmentGO:0048565750.061
oocyte differentiationGO:000999420.059
posttranscriptional regulation of gene expressionGO:00106082130.057
regulation of gene expression epigeneticGO:0040029730.057
positive regulation of dna metabolic processGO:0051054730.056
cellular amino acid metabolic processGO:00065201160.054
response to reactive oxygen speciesGO:0000302610.054
cell divisionGO:00513011680.054
Worm
positive regulation of cell cycleGO:00457871400.054
response to light stimulusGO:0009416870.053
dna recombinationGO:0006310770.052
cellular response to growth factor stimulusGO:00713631970.052
mitotic spindle organizationGO:0007052270.052
tube developmentGO:00352951250.052
regulation of dna dependent dna replication initiationGO:003017430.051
rna processingGO:00063962550.051
dna integrity checkpointGO:0031570710.049
regulation of mitotic cell cycleGO:00073461890.049
female gamete generationGO:000729220.049
positive regulation of cellular amino acid metabolic processGO:004576430.048
dna damage response signal transduction by p53 class mediatorGO:0030330440.047
dna duplex unwindingGO:0032508300.047
dna synthesis involved in dna repairGO:000073160.046
atp catabolic processGO:00062001570.044
embryo development ending in birth or egg hatchingGO:0009792340.044
Worm
negative regulation of programmed cell deathGO:00430693210.043
dna geometric changeGO:0032392320.042
ras protein signal transductionGO:0007265730.040
negative regulation of phosphate metabolic processGO:00459362670.040
regulation of chromosome organizationGO:00330441030.039
purine containing compound catabolic processGO:00725234110.039
ribonucleoside triphosphate catabolic processGO:00092033910.038
regulation of cell cycle arrestGO:0071156360.037
ribonucleoside catabolic processGO:00424544060.037
chromatin silencingGO:0006342120.037
protein catabolic processGO:00301633250.036
sex differentiationGO:0007548450.036
positive regulation of hydrolase activityGO:00513453310.036
nucleoside monophosphate catabolic processGO:00091251590.035
anatomical structure formation involved in morphogenesisGO:00486462840.035
covalent chromatin modificationGO:00165692540.034
positive regulation of cell proliferationGO:00082843010.034
chromatin modificationGO:00165682980.034
positive regulation of cell cycle arrestGO:0071158230.033
nuclear divisionGO:00002801280.033
negative regulation of protein metabolic processGO:00512483910.033
response to oxygen containing compoundGO:19017003690.033
negative regulation of apoptotic processGO:00430663160.033
response to inorganic substanceGO:00100351270.032
cellular component morphogenesisGO:00329893140.032
purine nucleoside triphosphate catabolic processGO:00091463920.031
cellular macromolecular complex assemblyGO:00346223240.031
positive regulation of protein phosphorylationGO:00019343130.031
purine ribonucleotide catabolic processGO:00091544040.030
dephosphorylationGO:00163112090.030
purine ribonucleoside triphosphate catabolic processGO:00092073910.029
positive regulation of mitotic cell cycleGO:0045931600.029
regulation of dna repairGO:0006282470.029
protein processingGO:00164852260.029
oocyte maturationGO:000155610.029
gene conversionGO:003582210.028
centrosome organizationGO:0051297580.028
nucleoside catabolic processGO:00091644080.028
nucleoside triphosphate metabolic processGO:00091414220.027
purine nucleotide catabolic processGO:00061954050.027
protein modification by small protein conjugationGO:00324463420.026
atp metabolic processGO:00460341760.026
regulation of cell cycle g1 s phase transitionGO:1902806420.026
nucleic acid phosphodiester bond hydrolysisGO:00903051020.026
Yeast Mouse
negative regulation of cellular protein metabolic processGO:00322693530.026
nervous system developmentGO:00073992930.026
negative regulation of gene expression epigeneticGO:0045814190.025
regulation of response to dna damage stimulusGO:2001020940.025
sister chromatid cohesionGO:0007062240.024
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayGO:190103030.024
myosin filament assemblyGO:003103420.024
glycosyl compound catabolic processGO:19016584130.024
purine ribonucleoside metabolic processGO:00461284370.024
regulation of proteolysisGO:00301622930.023
positive regulation of programmed cell deathGO:00430682490.023
regulation of chromosome segregationGO:0051983440.023
chromatin organizationGO:00063253510.023
organ morphogenesisGO:00098871470.023
spermatid developmentGO:000728640.022
alpha amino acid metabolic processGO:1901605720.022
nucleoside monophosphate metabolic processGO:00091231910.022
nucleoside phosphate catabolic processGO:19012924120.022
leukocyte apoptotic processGO:0071887310.022
regulation of cellular ketone metabolic processGO:0010565500.022
neurogenesisGO:00220081690.022
immune responseGO:00069553070.022
stem cell differentiationGO:0048863930.021
positive regulation of dna repairGO:0045739250.021
response to oxidative stressGO:00069791210.021
negative regulation of catalytic activityGO:00430863350.021
regulation of cellular amino acid metabolic processGO:000652160.021
response to growth factorGO:00708482050.021
response to other organismGO:00517072610.021
interspecies interaction between organismsGO:00444191560.021
purine ribonucleoside monophosphate catabolic processGO:00091691580.021
rna interferenceGO:001624640.020
positive regulation of cellular catabolic processGO:00313312840.020
purine ribonucleoside catabolic processGO:00461303980.020
response to radiationGO:00093141510.020
regulation of meiotic cell cycleGO:005144540.020
cellular response to abiotic stimulusGO:00712141170.019
regulation of g1 s transition of mitotic cell cycleGO:2000045400.019
dna damage response signal transduction resulting in transcriptionGO:0042772120.019
ribonucleotide catabolic processGO:00092614050.019
negative regulation of intracellular signal transductionGO:19025321830.019
protein maturationGO:00516042330.019
negative regulation of cell cycle phase transitionGO:1901988890.019
ubiquitin dependent protein catabolic processGO:00065112060.018
positive regulation of catabolic processGO:00098963100.018
myosin filament organizationGO:003103320.018
generation of neuronsGO:00486991520.018
mitotic nuclear divisionGO:00070671190.018
detection of stimulusGO:0051606850.018
ribonucleoside triphosphate metabolic processGO:00091994120.018
protein ubiquitinationGO:00165673140.018
digestive system developmentGO:0055123750.018
purine nucleoside monophosphate metabolic processGO:00091261860.017
cellular protein catabolic processGO:00442572610.017
gonad developmentGO:0008406340.017
oogenesisGO:004847720.017
multi organism cellular processGO:00447641560.017
regulation of peptidase activityGO:00525471800.017
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.017
response to biotic stimulusGO:00096072760.017
cellular modified amino acid metabolic processGO:0006575640.016
microtubule organizing center organizationGO:0031023620.016
sister chromatid segregationGO:0000819540.016
positive regulation of cellular amine metabolic processGO:003324070.016
epithelium developmentGO:00604292270.016
spermatid differentiationGO:004851540.016
histone modificationGO:00165702510.016
g2 m transition of mitotic cell cycleGO:0000086410.016
cell morphogenesisGO:00009022960.016
regulation of apoptotic signaling pathwayGO:20012331750.016
membrane organizationGO:00610242920.016
cell growthGO:00160491600.015
multi organism reproductive processGO:0044703540.015
nucleotide catabolic processGO:00091664080.015
positive regulation of proteolysisGO:00458621420.015
regulation of multi organism processGO:00439001570.015
apoptotic signaling pathwayGO:00971902680.015
reproductionGO:0000003630.015
humoral immune responseGO:0006959490.015
response to oxygen levelsGO:00704821000.015
regulation of cell diameterGO:006030510.015
regenerationGO:003109940.015
signal transduction in response to dna damageGO:0042770570.015
positive regulation of response to dna damage stimulusGO:2001022430.014
regulation of cellular amine metabolic processGO:0033238110.014
maintenance of dna repeat elementsGO:004357040.014
generation of precursor metabolites and energyGO:0006091680.014
cellular amine metabolic processGO:0044106410.014
positive regulation of cell deathGO:00109422630.014
maintenance of locationGO:00512351120.014
negative regulation of cell proliferationGO:00082852280.014
enzyme linked receptor protein signaling pathwayGO:00071673030.014
deoxyribose phosphate metabolic processGO:001969260.014
response to fungusGO:000962040.014
reproductive system developmentGO:0061458560.013
response to external biotic stimulusGO:00432072610.013
regulation of cellular response to stressGO:00801352440.013
purine nucleoside catabolic processGO:00061523980.013
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.013
2 deoxyribonucleotide metabolic processGO:000939460.013
proteolysis involved in cellular protein catabolic processGO:00516032440.013
compound eye developmentGO:004874910.013
regulation of immune effector processGO:0002697910.012
cilium morphogenesisGO:0060271750.012
response to organic cyclic compoundGO:00140702040.012
signal transduction by p53 class mediatorGO:0072331720.012
positive regulation of organelle organizationGO:00106381950.012
cell projection organizationGO:00300302520.012
sensory organ developmentGO:0007423520.012
growthGO:00400072020.012
dna packagingGO:0006323770.012
nucleotide biosynthetic processGO:00091651090.012
small gtpase mediated signal transductionGO:0007264780.012
nucleoside triphosphate catabolic processGO:00091433940.012
rna phosphodiester bond hydrolysisGO:0090501350.012
cell fate determinationGO:000170930.012
viral life cycleGO:00190581320.012
nucleus organizationGO:0006997280.012
regulation of proteasomal protein catabolic processGO:0061136870.012
regulation of protein localizationGO:00328802960.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.012
cellular component assembly involved in morphogenesisGO:0010927730.011
immune effector processGO:00022521590.011
positive regulation of developmental processGO:00510943140.011
multicellular organismal reproductive processGO:0048609400.011
negative regulation of dna metabolic processGO:0051053570.011
peptidyl tyrosine dephosphorylationGO:0035335360.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
protein localization to organelleGO:00333652800.011
peptidyl lysine modificationGO:00182051440.011
epithelial cell differentiationGO:00308551410.011
lymphocyte activationGO:00466491330.011
metaphase anaphase transition of cell cycleGO:0044784210.011
eye developmentGO:0001654420.010
cilium assemblyGO:0042384630.010
regulation of kinase activityGO:00435493140.010
adult locomotory behaviorGO:000834410.010
positive regulation of apoptotic processGO:00430652460.010
protein oligomerizationGO:00512591730.010
purine nucleoside triphosphate metabolic processGO:00091444120.010
meiotic chromosome segregationGO:004513240.010
regulation of viral genome replicationGO:0045069480.010
hemopoiesisGO:00300971800.010
symbiosis encompassing mutualism through parasitismGO:00444031560.010

POLD1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.079
disease of cellular proliferationDOID:145661740.079
disease of metabolismDOID:00146672950.035
musculoskeletal system diseaseDOID:172230.029
connective tissue diseaseDOID:651090.029
bone diseaseDOID:0080001880.029
bone development diseaseDOID:0080006550.028
neuropathyDOID:870520.014
peripheral neuropathyDOID:0060053120.014
nervous system diseaseDOID:8634310.014
organ system cancerDOID:00506861640.013
dysostosisDOID:1934220.013
gastrointestinal system cancerDOID:3119520.011
large intestine cancerDOID:5672290.005
intestinal cancerDOID:10155290.005
colorectal cancerDOID:9256290.004