Homo sapiens

0 known processes

POLD4

polymerase (DNA-directed), delta 4

(Aliases: p12,POLDS)

POLD4 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cofactor metabolic processGO:0051186870.134
cell projection organizationGO:00300302520.130
cellular amino acid metabolic processGO:00065201160.116
ribonucleoside triphosphate catabolic processGO:00092033910.107
oxidation reduction processGO:00551143960.106
positive regulation of developmental processGO:00510943140.105
purine containing compound catabolic processGO:00725234110.096
cellular macromolecular complex assemblyGO:00346223240.094
glycosyl compound catabolic processGO:19016584130.088
single organism membrane organizationGO:00448022680.087
regulation of cellular component biogenesisGO:00440872810.086
negative regulation of cellular protein metabolic processGO:00322693530.085
ribonucleoside catabolic processGO:00424544060.081
purine ribonucleoside catabolic processGO:00461303980.081
positive regulation of locomotionGO:00400171860.080
actin filament based processGO:00300292240.077
vesicle mediated transportGO:00161923710.076
determination of adult lifespanGO:000834020.075
glutathione metabolic processGO:0006749200.072
organophosphate catabolic processGO:00464344300.071
regenerationGO:003109940.070
ribonucleotide catabolic processGO:00092614050.070
positive regulation of cellular component biogenesisGO:00440891580.070
nucleoside catabolic processGO:00091644080.068
ras protein signal transductionGO:0007265730.067
positive regulation of protein kinase activityGO:00458601900.066
cellular amine metabolic processGO:0044106410.066
gtp catabolic processGO:00061842370.063
purine ribonucleoside triphosphate catabolic processGO:00092073910.063
purine ribonucleoside metabolic processGO:00461284370.062
positive regulation of gtp catabolic processGO:00331261660.061
guanosine containing compound catabolic processGO:19010692390.060
purine nucleoside triphosphate catabolic processGO:00091463920.060
nucleoside phosphate catabolic processGO:19012924120.060
cellular protein complex assemblyGO:00436231880.060
regulation of cellular ketone metabolic processGO:0010565500.060
regulation of cellular amino acid metabolic processGO:000652160.059
cellular response to oxygen containing compoundGO:19017012760.058
gtp metabolic processGO:00460392390.058
nucleoside triphosphate metabolic processGO:00091414220.058
actin cytoskeleton organizationGO:00300362070.057
purine ribonucleoside triphosphate metabolic processGO:00092054110.056
positive regulation of hydrolase activityGO:00513453310.056
membrane organizationGO:00610242920.056
regulation of gtpase activityGO:00430871800.056
positive regulation of purine nucleotide catabolic processGO:00331231850.055
cellular lipid metabolic processGO:00442553030.054
purine nucleoside triphosphate metabolic processGO:00091444120.053
cellular ketone metabolic processGO:0042180800.053
regulation of anatomical structure morphogenesisGO:00226032860.052
regulation of rho gtpase activityGO:0032319660.052
rho protein signal transductionGO:0007266260.051
purine ribonucleotide catabolic processGO:00091544040.049
regulation of secretion by cellGO:19035301770.048
amine metabolic processGO:0009308440.047
regulation of cellular amine metabolic processGO:0033238110.047
regulation of cytoskeleton organizationGO:00514931770.047
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.047
cell growthGO:00160491600.046
positive regulation of phosphorylationGO:00423273940.046
positive regulation of kinase activityGO:00336742040.046
regulation of protein localizationGO:00328802960.045
positive regulation of cellular catabolic processGO:00313312840.045
regulation of transferase activityGO:00513383550.044
response to oxygen containing compoundGO:19017003690.044
negative regulation of cellular component organizationGO:00511292350.044
actin polymerization or depolymerizationGO:0008154560.044
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.043
regulation of gtp catabolic processGO:00331241800.043
positive regulation of protein phosphorylationGO:00019343130.043
positive regulation of ras gtpase activityGO:00323201170.042
response to lipidGO:00339932060.042
regulation of kinase activityGO:00435493140.042
response to external biotic stimulusGO:00432072610.042
regulation of actin filament based processGO:00329701410.042
cytoplasmic transportGO:00164823790.041
positive regulation of gtpase activityGO:00435471660.041
guanosine containing compound metabolic processGO:19010682440.040
ion homeostasisGO:00508012300.040
regulation of erk1 and erk2 cascadeGO:0070372990.040
positive regulation of nucleotide catabolic processGO:00308131850.039
metal ion transportGO:00300012720.039
regulation of epithelial cell proliferationGO:00506781130.039
cellular macromolecule catabolic processGO:00442653800.038
negative regulation of cellular amino acid metabolic processGO:004576320.038
negative regulation of phosphorus metabolic processGO:00105632670.038
ribonucleoside triphosphate metabolic processGO:00091994120.037
vesicle organizationGO:0016050620.037
positive regulation of catabolic processGO:00098963100.037
regulation of nucleotide metabolic processGO:00061402690.036
purine nucleotide catabolic processGO:00061954050.036
regulation of purine nucleotide metabolic processGO:19005422640.036
microtubule based processGO:00070172100.035
enzyme linked receptor protein signaling pathwayGO:00071673030.035
regulation of ras gtpase activityGO:00323181280.034
negative regulation of protein metabolic processGO:00512483910.034
positive regulation of cytoskeleton organizationGO:0051495830.034
negative regulation of catalytic activityGO:00430863350.034
nucleotide catabolic processGO:00091664080.034
regulation of cell growthGO:00015581350.033
purine nucleoside catabolic processGO:00061523980.033
small gtpase mediated signal transductionGO:0007264780.033
regulation of protein kinase activityGO:00458592890.033
epithelial cell migrationGO:00106311190.032
positive regulation of cellular amino acid metabolic processGO:004576430.032
response to extracellular stimulusGO:0009991850.031
multicellular organismal agingGO:001025930.031
positive regulation of erk1 and erk2 cascadeGO:0070374750.031
positive regulation of transportGO:00510503360.031
cellular homeostasisGO:00197251960.031
regulation of actin cytoskeleton organizationGO:00329561160.031
growthGO:00400072020.030
somatic muscle developmentGO:000752510.030
positive regulation of organelle organizationGO:00106381950.030
nucleoside triphosphate catabolic processGO:00091433940.030
negative regulation of cell proliferationGO:00082852280.030
positive regulation of cell projection organizationGO:0031346640.030
post embryonic developmentGO:000979120.029
sulfur compound metabolic processGO:00067901010.029
cell adhesionGO:00071553250.029
negative regulation of phosphate metabolic processGO:00459362670.029
negative regulation of organelle organizationGO:00106391260.029
positive regulation of immune system processGO:00026842830.029
cell projection assemblyGO:00300311260.029
response to biotic stimulusGO:00096072760.029
peptide metabolic processGO:0006518510.029
negative regulation of hydrolase activityGO:00513461820.029
positive regulation of nucleoside metabolic processGO:00459791860.029
positive regulation of cellular component movementGO:00512721810.028
defense responseGO:00069523150.028
positive regulation of cell migrationGO:00303351720.028
chemical homeostasisGO:00488783060.028
regulation of nucleotide catabolic processGO:00308112050.028
endothelial cell migrationGO:0043542860.028
cell part morphogenesisGO:00329901370.028
positive regulation of nucleotide metabolic processGO:00459812300.028
organelle fusionGO:0048284360.027
cell morphogenesisGO:00009022960.027
endosomal transportGO:00161971290.027
nucleic acid phosphodiester bond hydrolysisGO:00903051020.027
positive regulation of rac gtpase activityGO:0032855310.027
positive regulation of cellular amine metabolic processGO:003324070.027
maintenance of cell polarityGO:003001120.027
positive regulation of cellular component organizationGO:00511303760.027
epithelium developmentGO:00604292270.026
cellular response to dna damage stimulusGO:00069743790.026
cellular component morphogenesisGO:00329893140.026
neuron projection regenerationGO:003110210.026
regulation of cellular component movementGO:00512703340.026
response to inorganic substanceGO:00100351270.026
biological adhesionGO:00226103310.026
positive regulation of cell motilityGO:20001471770.025
negative regulation of cellular amine metabolic processGO:003323930.025
response to woundingGO:00096111680.025
regulation of adenylate cyclase activityGO:0045761170.025
regulation of nucleoside metabolic processGO:00091182090.025
response to nutrient levelsGO:0031667810.025
lipid metabolic processGO:00066293810.025
viral life cycleGO:00190581320.024
regulation of purine nucleotide catabolic processGO:00331212050.024
secretion by cellGO:00329402260.024
myeloid cell differentiationGO:00300991170.024
positive regulation of transferase activityGO:00513472270.024
negative regulation of multicellular organismal processGO:00512413170.024
mapk cascadeGO:00001652880.024
positive regulation of purine nucleotide metabolic processGO:19005442270.023
regulation of secretionGO:00510461940.023
cellular cation homeostasisGO:00300031630.023
calcium ion transportGO:00068161470.023
microtubule cytoskeleton organizationGO:00002261760.023
neurological system processGO:00508771630.022
regulation of cell migrationGO:00303342890.022
regulation of establishment of protein localizationGO:00702012420.022
cellular chemical homeostasisGO:00550821800.022
regulation of ras protein signal transductionGO:00465781550.022
cellular response to nutrient levelsGO:0031669690.022
interspecies interaction between organismsGO:00444191560.021
epithelial cell proliferationGO:00506731280.021
regulation of protein serine threonine kinase activityGO:00719001790.021
secretionGO:00469032540.021
regulation of stress activated protein kinase signaling cascadeGO:0070302850.021
nervous system developmentGO:00073992930.021
small molecule biosynthetic processGO:00442831570.021
regulation of cellular response to stressGO:00801352440.021
wound healingGO:00420601150.021
hemopoiesisGO:00300971800.021
protein polymerizationGO:0051258710.021
response to other organismGO:00517072610.021
regulation of cell morphogenesisGO:00226041530.021
positive regulation of protein serine threonine kinase activityGO:00719021190.020
cellular response to endogenous stimulusGO:00714953360.020
response to oxidative stressGO:00069791210.020
mitotic cell cycleGO:00002783260.020
negative regulation of apoptotic processGO:00430663160.020
cellular amide metabolic processGO:0043603690.020
protein maturationGO:00516042330.020
autophagyGO:0006914880.020
immune system developmentGO:00025201950.020
organonitrogen compound biosynthetic processGO:19015662000.020
positive regulation of mapk cascadeGO:00434101900.020
vacuole organizationGO:0007033440.020
erk1 and erk2 cascadeGO:00703711040.020
organelle assemblyGO:00709251760.019
regulation of small gtpase mediated signal transductionGO:00510561560.019
mitochondrion organizationGO:00070051560.019
response to acid chemicalGO:0001101660.019
cation transportGO:00068123310.019
tissue migrationGO:00901301190.019
regulation of vesicle mediated transportGO:00606271300.019
proteolysis involved in cellular protein catabolic processGO:00516032440.019
intracellular protein transportGO:00068862700.019
single organism cellular localizationGO:19025803320.018
cellular modified amino acid metabolic processGO:0006575640.018
epithelium migrationGO:00901321190.018
positive regulation of axon extensionGO:004577340.018
anatomical structure formation involved in morphogenesisGO:00486462840.018
cellular ion homeostasisGO:00068731680.018
cell projection morphogenesisGO:00488581290.018
cell divisionGO:00513011680.018
regulation of cellular component sizeGO:0032535820.018
regulation of intracellular transportGO:00323861950.018
establishment or maintenance of apical basal cell polarityGO:003508820.017
protein kinase b signalingGO:0043491690.017
regulation of protein polymerizationGO:0032271630.017
ubiquitin dependent protein catabolic processGO:00065112060.017
neuron developmentGO:00486661130.017
response to abiotic stimulusGO:00096283360.017
reactive nitrogen species metabolic processGO:200105730.017
g protein coupled receptor signaling pathwayGO:00071862070.017
single organism cell adhesionGO:00986021790.017
lytic vacuole organizationGO:0080171240.017
regulation of immune responseGO:00507762010.017
nucleotide biosynthetic processGO:00091651090.017
actin filament organizationGO:00070151280.017
regulation of anatomical structure sizeGO:00900661010.017
regulation of protein transportGO:00512232130.016
modification dependent macromolecule catabolic processGO:00436322120.016
signal transduction by phosphorylationGO:00230142970.016
cellular response to growth factor stimulusGO:00713631970.016
adult locomotory behaviorGO:000834410.016
spermatid differentiationGO:004851540.016
cellular protein catabolic processGO:00442572610.016
divalent inorganic cation transportGO:00725111580.016
regulation of cell projection organizationGO:00313441070.016
regulation of locomotionGO:00400123290.016
regulation of wnt signaling pathwayGO:00301111230.016
regulation of cell cycleGO:00517263930.016
blood vessel developmentGO:00015681720.016
symbiosis encompassing mutualism through parasitismGO:00444031560.016
protein ubiquitinationGO:00165673140.015
positive regulation of cell proliferationGO:00082843010.015
response to organic cyclic compoundGO:00140702040.015
segmentationGO:003528240.015
negative regulation of phosphorylationGO:00423261740.015
protein oligomerizationGO:00512591730.015
neuron projection developmentGO:00311751060.015
ribonucleotide biosynthetic processGO:0009260810.015
peptidyl tyrosine modificationGO:00182121700.015
angiogenesisGO:00015251470.015
coenzyme metabolic processGO:0006732650.015
maintenance of locationGO:00512351120.015
positive regulation of synaptic transmissionGO:005080640.015
dna repairGO:00062811980.015
cellular response to extracellular stimulusGO:0031668720.015
positive regulation of stress activated mapk cascadeGO:0032874600.015
system processGO:00030083490.015
response to organonitrogen compoundGO:00102431560.015
divalent metal ion transportGO:00708381520.014
negative regulation of cytoskeleton organizationGO:0051494450.014
carbohydrate metabolic processGO:00059752070.014
immune responseGO:00069553070.014
single organism carbohydrate metabolic processGO:00447231930.014
regulation of jnk cascadeGO:0046328730.014
hematopoietic or lymphoid organ developmentGO:00485341860.014
dephosphorylationGO:00163112090.014
innate immune responseGO:00450871780.014
response to growth factorGO:00708482050.014
regulation of growthGO:00400081650.014
fatty acid biosynthetic processGO:0006633460.014
negative regulation of protein modification processGO:00314002000.014
negative regulation of programmed cell deathGO:00430693210.014
head developmentGO:00603221080.014
modification dependent protein catabolic processGO:00199412090.014
protein localization to membraneGO:00726571600.014
regulation of ion transportGO:00432691890.014
positive regulation of rho gtpase activityGO:0032321560.014
organic acid biosynthetic processGO:0016053970.014
membrane fusionGO:0061025430.014
cell cycle arrestGO:0007050710.014
regulation of multi organism processGO:00439001570.014
response to bacteriumGO:00096171440.014
multi organism cellular processGO:00447641560.014
carboxylic acid biosynthetic processGO:0046394970.014
regulation of cell projection assemblyGO:0060491470.014
negative regulation of protein phosphorylationGO:00019331400.014
dna replicationGO:00062601160.013
negative regulation of intracellular signal transductionGO:19025321830.013
protein glycosylationGO:0006486620.013
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.013
positive regulation of response to external stimulusGO:0032103880.013
cellular response to cytokine stimulusGO:00713451810.013
female gamete generationGO:000729220.013
regulation of cell adhesionGO:00301551660.013
response to fungusGO:000962040.013
cell morphogenesis involved in differentiationGO:00009041440.013
regulation of defense responseGO:00313471540.013
viral processGO:00160321460.013
establishment of protein localization to membraneGO:00901501210.013
positive regulation of epithelial cell proliferationGO:0050679650.013
regulation of mapk cascadeGO:00434082620.013
locomotory behaviorGO:000762610.013
positive regulation of cell morphogenesis involved in differentiationGO:0010770500.013
cellular response to external stimulusGO:00714961110.013
regulation of dna metabolic processGO:00510521530.013
nucleoside phosphate biosynthetic processGO:19012931090.013
protein acylationGO:00435431380.013
wnt signaling pathwayGO:00160551560.013
cell developmentGO:00484683280.013
monocarboxylic acid metabolic processGO:00327871850.013
regulation of camp biosynthetic processGO:0030817450.013
cellular response to abiotic stimulusGO:00712141170.013
negative regulation of catabolic processGO:00098951040.012
positive regulation of ion transportGO:0043270870.012
positive regulation of protein transportGO:00512221350.012
negative regulation of cell deathGO:00605483450.012
embryonic hemopoiesisGO:003516240.012
negative regulation of cellular catabolic processGO:0031330830.012
generation of precursor metabolites and energyGO:0006091680.012
response to hormoneGO:00097251750.012
protein modification by small protein conjugationGO:00324463420.012
cytokine productionGO:00018162470.012
ossificationGO:00015031210.012
memoryGO:000761330.012
regulation of nervous system developmentGO:0051960880.012
apoptotic signaling pathwayGO:00971902680.012
peripheral nervous system developmentGO:000742220.012
positive regulation of apoptotic processGO:00430652460.012
regulation of actin polymerization or depolymerizationGO:0008064560.012
erbb signaling pathwayGO:0038127440.012
cellular response to organonitrogen compoundGO:00714171240.012
cytokine mediated signaling pathwayGO:00192211090.012
plasma membrane organizationGO:00070091150.012
negative regulation of cell cycleGO:00457861930.012
regulation of vasculature developmentGO:1901342970.012
cellular component disassemblyGO:0022411920.012
neuromuscular junction developmentGO:000752830.012
central nervous system developmentGO:00074171230.012
regulation of cyclic nucleotide biosynthetic processGO:0030802490.012
cellular response to lipidGO:00713961270.011
cellular response to nitrogen compoundGO:19016991440.011
regulation of calcium ion transportGO:0051924790.011
protein catabolic processGO:00301633250.011
reactive oxygen species metabolic processGO:0072593750.011
organelle fissionGO:00482851490.011
lysosome organizationGO:0007040240.011
positive regulation of secretionGO:00510471160.011
generation of neuronsGO:00486991520.011
response to molecule of bacterial originGO:0002237820.011
response to nitrogen compoundGO:19016981840.011
reactive oxygen species biosynthetic processGO:190340940.011
purine nucleotide biosynthetic processGO:0006164840.011
neurogenesisGO:00220081690.011
defense response to other organismGO:00985421290.011
stem cell divisionGO:001714520.011
spermatid developmentGO:000728640.011
blastoderm segmentationGO:000735020.011
regulation of synaptic plasticityGO:004816730.011
vasculature developmentGO:00019441810.011
sensory perception of painGO:001923340.011
positive regulation of cell growthGO:0030307480.011
carbohydrate derivative biosynthetic processGO:19011372070.011
regulation of response to external stimulusGO:00321012220.011
peptidyl tyrosine phosphorylationGO:00181081700.011
regulation of blood vessel remodelingGO:006031220.011
endomembrane system organizationGO:00102561960.011
protein acetylationGO:00064731160.011
protein localization to plasma membraneGO:0072659930.011
circulatory system developmentGO:00723592620.011
cytosolic calcium ion homeostasisGO:0051480890.011
positive regulation of calcium ion transportGO:0051928510.011
neuroblast proliferationGO:000740540.011
lipid localizationGO:00108761060.011
positive regulation of secretion by cellGO:19035321080.011
peptidyl lysine acetylationGO:00183941010.010
positive regulation of intracellular protein transportGO:0090316760.010
immune effector processGO:00022521590.010
regulation of actin filament lengthGO:0030832560.010
negative regulation of transferase activityGO:00513481240.010
regulation of homeostatic processGO:00328441210.010
regulation of exocytosisGO:0017157460.010
cell cycle phase transitionGO:00447701730.010
fatty acid metabolic processGO:00066311150.010
organophosphate biosynthetic processGO:00904071630.010
nadph oxidationGO:007099530.010
regulation of actin filament polymerizationGO:0030833500.010
cyclic nucleotide biosynthetic processGO:0009190610.010
response to starvationGO:0042594590.010
regulation of protein localization to plasma membraneGO:1903076400.010
organic hydroxy compound metabolic processGO:19016151470.010
regulation of cyclase activityGO:0031279190.010
negative regulation of protein kinase activityGO:0006469980.010
oogenesisGO:004847720.010
inorganic cation transmembrane transportGO:00986621940.010

POLD4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.047
cancerDOID:1621670.033
disease of metabolismDOID:00146672950.032
organ system cancerDOID:00506861640.025
central nervous system diseaseDOID:3311860.021
nervous system diseaseDOID:8634310.021
immune system diseaseDOID:29141550.020
musculoskeletal system diseaseDOID:172230.015