Homo sapiens

84 known processes

DICER1

dicer 1, ribonuclease type III

(Aliases: DCR1,KIAA0928,Dicer,HERNA)

DICER1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
production of mirnas involved in gene silencing by mirnaGO:0035196121.000
gene silencing by mirnaGO:0035195231.000
targeting of mrna for destruction involved in rna interferenceGO:003042331.000
production of sirna involved in rna interferenceGO:003042230.998
posttranscriptional gene silencing by rnaGO:0035194250.997
pre mirna processingGO:003105480.996
posttranscriptional gene silencingGO:0016441250.995
gene silencing by rnaGO:0031047260.994
ncrna metabolic processGO:00346601080.994
positive regulation of mrna 3 end processingGO:0031442120.993
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decayGO:190015180.991
production of small rna involved in gene silencing by rnaGO:0070918130.990
rna processingGO:00063962550.989
positive regulation of mrna catabolic processGO:0061014100.987
dsrna fragmentationGO:0031050130.983
small rna loading onto riscGO:007092230.980
Fly
regulation of mrna catabolic processGO:0061013130.978
gene silencingGO:0016458490.976
ribonucleoprotein complex biogenesisGO:00226131160.970
positive regulation of mrna metabolic processGO:1903313190.967
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decayGO:190015380.963
stem cell developmentGO:0048864690.953
Mouse
posttranscriptional regulation of gene expressionGO:00106082130.950
regulation of gene expression epigeneticGO:0040029730.943
ribonucleoprotein complex subunit organizationGO:0071826810.939
positive regulation of mrna processingGO:0050685170.913
cellular macromolecular complex assemblyGO:00346223240.909
regulation of mrna 3 end processingGO:0031440120.906
cellular response to organic cyclic compoundGO:00714071270.901
positive regulation of nuclear transcribed mrna poly a tail shorteningGO:006021380.880
rna interferenceGO:001624640.877
translationGO:00064121320.849
viral life cycleGO:00190581320.846
Mouse
regulation of viral processGO:00507921030.844
Mouse
stem cell maintenanceGO:0019827190.836
Mouse
regulation of translationGO:0006417890.823
response to organic cyclic compoundGO:00140702040.812
negative regulation of developmental processGO:00510932470.794
Mouse
outer ear morphogenesisGO:004247320.792
negative regulation of cell differentiationGO:00455961710.792
Mouse
cellular response to dsrnaGO:0071359190.781
mrna 3 end processingGO:0031124240.778
chromatin organizationGO:00063253510.777
response to dsrnaGO:0043331250.769
associative learningGO:000830610.767
Worm
response to virusGO:00096151260.746
Human Mouse
regulation of nuclear transcribed mrna poly a tail shorteningGO:006021180.745
multi organism cellular processGO:00447641560.740
Human Mouse
stem cell differentiationGO:0048863930.716
Mouse
regulation of multi organism processGO:00439001570.710
Human Mouse
mrna cleavage involved in gene silencing by mirnaGO:003527920.706
Zebrafish
ribonucleoprotein complex assemblyGO:0022618780.695
negative regulation of defense response to virusGO:0050687100.690
Human
viral processGO:00160321460.685
Mouse
regulation of defense responseGO:00313471540.634
Human
cellular macromolecule catabolic processGO:00442653800.619
Worm
viral genome replicationGO:0019079500.592
Mouse
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.574
Mouse
cellular response to nitrogen compoundGO:19016991440.565
regulation of cell differentiationGO:00455953930.527
Mouse
negative regulation of multi organism processGO:0043901920.503
Human
negative regulation of defense responseGO:0031348470.484
Human
response to other organismGO:00517072610.441
Human Mouse
mrna processingGO:00063971330.425
Zebrafish
regulation of gene silencingGO:0060968240.425
Worm
spermatid developmentGO:000728640.390
response to biotic stimulusGO:00096072760.386
Human Mouse
rna 3 end processingGO:0031123350.377
cell developmentGO:00484683280.377
Mouse Fly
symbiosis encompassing mutualism through parasitismGO:00444031560.365
Mouse
immune effector processGO:00022521590.354
Human Mouse
mrna metabolic processGO:00160711750.353
Zebrafish
regulation of response to biotic stimulusGO:0002831550.350
Human
segmentationGO:003528240.345
Fly
ncrna processingGO:0034470830.334
negative regulation of immune system processGO:00026831360.323
Human
regulation of viral genome replicationGO:0045069480.322
Mouse
negative regulation of response to external stimulusGO:0032102830.321
Human
viral transcriptionGO:0019083350.319
regulation of viral transcriptionGO:0046782340.305
negative regulation of protein metabolic processGO:00512483910.299
regulation of defense response to virus by hostGO:0050691220.298
Human
positive regulation of catabolic processGO:00098963100.298
hematopoietic or lymphoid organ developmentGO:00485341860.297
Mouse
interspecies interaction between organismsGO:00444191560.295
Mouse
regulation of mrna metabolic processGO:1903311530.294
multi organism metabolic processGO:0044033410.278
negative regulation of immune effector processGO:0002698380.278
Human
nuclear transcribed mrna poly a tail shorteningGO:000028980.247
regulation of gene silencing by rnaGO:006096660.235
Worm
response to nitrogen compoundGO:19016981840.226
dosage compensationGO:000754930.210
positive regulation of viral processGO:0048524370.204
single organism cellular localizationGO:19025803320.204
Human
viral gene expressionGO:0019080350.203
blastoderm segmentationGO:000735020.202
Fly
negative regulation of translationGO:0017148370.201
regulation of neurological system processGO:003164460.194
Mouse
defense response to virusGO:0051607710.192
Human Mouse
regulation of mrna processingGO:0050684480.189
mirna metabolic processGO:0010586100.188
Mouse
spermatid differentiationGO:004851540.179
mrna catabolic processGO:0006402560.170
mirna loading onto risc involved in gene silencing by mirnaGO:003528020.167
rna catabolic processGO:0006401710.166
Worm
regulation of system processGO:00440571010.162
Mouse
negative regulation of cellular protein metabolic processGO:00322693530.158
signal transduction by phosphorylationGO:00230142970.149
positive regulation of multi organism processGO:0043902560.149
positive regulation of cellular catabolic processGO:00313312840.133
cytoplasmic transportGO:00164823790.127
Human
chromatin modificationGO:00165682980.120
neurological system processGO:00508771630.112
Mouse Worm
system processGO:00030083490.109
Mouse Worm
protein targetingGO:00066051870.106
Human
stem cell divisionGO:001714520.103
Fly
negative regulation of programmed cell deathGO:00430693210.101
growthGO:00400072020.095
Mouse
female gamete generationGO:000729220.094
Fly
defense response to other organismGO:00985421290.093
Human Mouse
protein modification by small protein conjugationGO:00324463420.092
Human
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288140.091
regulation of behaviorGO:0050795820.091
regulation of kinase activityGO:00435493140.088
reproductive processGO:00224141060.086
Mouse Worm Fly
rna phosphodiester bond hydrolysisGO:0090501350.084
positive regulation of apoptotic processGO:00430652460.084
nervous system developmentGO:00073992930.084
Zebrafish Mouse Fly
negative regulation of response to biotic stimulusGO:0002832180.084
Human
response to external biotic stimulusGO:00432072610.084
Human Mouse
defense responseGO:00069523150.082
Human Mouse Worm
single organism nuclear importGO:19025931040.080
Human
immune system developmentGO:00025201950.080
Mouse
anatomical structure formation involved in morphogenesisGO:00486462840.076
Mouse Fly
translational initiationGO:0006413480.072
negative regulation of cell deathGO:00605483450.071
mapk cascadeGO:00001652880.068
oogenesisGO:004847720.067
Fly
negative regulation of apoptotic processGO:00430663160.067
hemopoiesisGO:00300971800.067
regulation of defense response to virusGO:0050688330.067
Human
regulation of immune effector processGO:0002697910.066
Human
nuclear transcribed mrna catabolic processGO:0000956480.066
negative regulation of translation involved in gene silencing by mirnaGO:003527860.066
nucleic acid phosphodiester bond hydrolysisGO:00903051020.063
negative regulation of gene expression epigeneticGO:0045814190.058
positive regulation of protein phosphorylationGO:00019343130.055
positive regulation of phosphorylationGO:00423273940.054
single organism reproductive processGO:0044702980.054
Worm Fly
central nervous system developmentGO:00074171230.053
Zebrafish Mouse
regulation of transferase activityGO:00513383550.052
purine ribonucleoside triphosphate catabolic processGO:00092073910.052
regulation of cytokine productionGO:00018172320.051
Human
glycosyl compound catabolic processGO:19016584130.049
negative regulation of defense response to virus by hostGO:005068940.049
middle ear morphogenesisGO:004247410.048
regulation of response to external stimulusGO:00321012220.048
Human
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.048
ribonucleotide catabolic processGO:00092614050.046
protein autophosphorylationGO:00467771230.046
negative regulation of multicellular organismal processGO:00512413170.045
Human Mouse
chromatin silencingGO:0006342120.044
protein ubiquitinationGO:00165673140.044
positive regulation of mapk cascadeGO:00434101900.044
nucleoside triphosphate catabolic processGO:00091433940.044
regulation of cellular component biogenesisGO:00440872810.044
regulation of translation ncrna mediatedGO:004597460.043
cell projection organizationGO:00300302520.043
Mouse Fly
embryo developmentGO:00097901230.043
Mouse Fly
apoptotic signaling pathwayGO:00971902680.042
asymmetric stem cell divisionGO:009872210.042
protein targeting to nucleusGO:00447441040.042
Human
regulation of apoptotic signaling pathwayGO:20012331750.042
skeletal system developmentGO:0001501790.041
Mouse
positive regulation of kinase activityGO:00336742040.041
positive regulation of programmed cell deathGO:00430682490.041
rna splicingGO:00083801310.041
amine metabolic processGO:0009308440.041
negative regulation of protein modification processGO:00314002000.040
cellular component morphogenesisGO:00329893140.040
Mouse Fly
regulation of protein kinase activityGO:00458592890.040
histone modificationGO:00165702510.040
multicellular organismal agingGO:001025930.039
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.039
ribonucleoside triphosphate metabolic processGO:00091994120.039
nucleoside phosphate catabolic processGO:19012924120.038
vesicle mediated transportGO:00161923710.037
negative regulation of cellular component organizationGO:00511292350.036
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.035
protein deubiquitinationGO:0016579790.035
multicellular organism reproductionGO:0032504420.035
Worm Fly
regulation of stress activated protein kinase signaling cascadeGO:0070302850.035
positive regulation of protein kinase activityGO:00458601900.034
regulation of locomotionGO:00400123290.034
Human
regulation of cell motilityGO:20001452990.034
Human
learningGO:0007612110.034
Worm
ras protein signal transductionGO:0007265730.034
negative regulation of translation ncrna mediatedGO:004003360.033
proteasomal protein catabolic processGO:00104981760.033
positive regulation of cell deathGO:00109422630.033
response to endoplasmic reticulum stressGO:0034976490.033
behaviorGO:00076101120.033
Worm
intrinsic apoptotic signaling pathwayGO:00971931270.033
proteolysis involved in cellular protein catabolic processGO:00516032440.033
purine nucleoside catabolic processGO:00061523980.032
regulation of cellular ketone metabolic processGO:0010565500.032
embryonic hemopoiesisGO:003516240.032
purine ribonucleotide catabolic processGO:00091544040.032
negative regulation of catalytic activityGO:00430863350.031
purine containing compound catabolic processGO:00725234110.031
cellular amino acid metabolic processGO:00065201160.031
positive regulation of transferase activityGO:00513472270.031
oocyte differentiationGO:000999420.030
Fly
innate immune responseGO:00450871780.030
Human
activation of protein kinase activityGO:0032147900.030
oocyte developmentGO:004859910.029
positive regulation of cellular amine metabolic processGO:003324070.029
regulation of mapk cascadeGO:00434082620.029
regulation of purine nucleotide metabolic processGO:19005422640.029
purine ribonucleoside triphosphate metabolic processGO:00092054110.029
regulation of cellular response to stressGO:00801352440.028
immune responseGO:00069553070.028
Human
positive regulation of intracellular protein transportGO:0090316760.028
Human
nuclear transportGO:00511691790.028
Human
cognitionGO:0050890430.028
Worm
nuclear importGO:00511701060.027
Human
positive regulation of cell proliferationGO:00082843010.027
cellular response to nutrient levelsGO:0031669690.027
embryonic organ developmentGO:0048568360.027
stress activated protein kinase signaling cascadeGO:0031098940.027
purine nucleotide catabolic processGO:00061954050.026
negative regulation of cell proliferationGO:00082852280.026
Mouse
regulation of cell cycle processGO:00105642660.026
lipid metabolic processGO:00066293810.026
negative regulation of posttranscriptional gene silencingGO:006014930.025
heterochromatin organizationGO:007082860.025
compound eye developmentGO:004874910.025
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244280.025
regulation of protein complex assemblyGO:00432541470.025
positive regulation of developmental processGO:00510943140.024
Mouse
organophosphate catabolic processGO:00464344300.024
cell morphogenesisGO:00009022960.024
Mouse Fly
guanosine containing compound catabolic processGO:19010692390.024
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.024
protein deacylationGO:0035601390.023
positive regulation of stress activated mapk cascadeGO:0032874600.023
nucleotide catabolic processGO:00091664080.023
protein modification by small protein removalGO:0070646920.023
positive regulation of nf kappab transcription factor activityGO:0051092810.022
positive regulation of cellular amino acid metabolic processGO:004576430.021
regulation of chemokine productionGO:0032642310.021
ribonucleoside triphosphate catabolic processGO:00092033910.021
negative regulation of gene silencing by rnaGO:006096730.021
protein importGO:00170381300.021
Human
cellular response to endogenous stimulusGO:00714953360.021
purine ribonucleoside metabolic processGO:00461284370.021
hematopoietic stem cell differentiationGO:006021840.020
nucleoside triphosphate metabolic processGO:00091414220.020
multi organism reproductive processGO:0044703540.020
Worm Fly
regulation of cellular amine metabolic processGO:0033238110.020
lipid biosynthetic processGO:00086101770.020
protein localization to nucleusGO:00345041360.020
Human
rna phosphodiester bond hydrolysis endonucleolyticGO:0090502150.020
neuron projection developmentGO:00311751060.020
Mouse Fly
regulation of proteolysisGO:00301622930.020
regulation of sequence specific dna binding transcription factor activityGO:00510902110.020
atp metabolic processGO:00460341760.020
ribonucleoside monophosphate metabolic processGO:00091611870.020
mrna cleavageGO:000637950.019
Zebrafish
regulation of nucleoside metabolic processGO:00091182090.019
protein localization to organelleGO:00333652800.019
Human
cellular ketone metabolic processGO:0042180800.019
nucleoside catabolic processGO:00091644080.019
negative regulation of dna metabolic processGO:0051053570.019
histone deacetylationGO:0016575320.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
cell type specific apoptotic processGO:00972851250.018
Mouse
purine nucleoside monophosphate catabolic processGO:00091281580.018
regenerationGO:003109940.018
Mouse
single organism behaviorGO:0044708280.018
Worm
negative regulation of cellular amine metabolic processGO:003323930.018
hematopoietic progenitor cell differentiationGO:0002244380.018
regulation of innate immune responseGO:0045088970.018
Human
regulation of cytoskeleton organizationGO:00514931770.018
reactive oxygen species biosynthetic processGO:190340940.018
regulation of dna metabolic processGO:00510521530.018
nucleobase containing compound transportGO:0015931510.018
Fly
cellular lipid metabolic processGO:00442553030.018
locomotory behaviorGO:000762610.018
macromolecule deacylationGO:0098732410.018
actin filament based processGO:00300292240.017
neuromuscular junction developmentGO:000752830.017
cell fate determinationGO:000170930.017
Fly
head developmentGO:00603221080.017
Zebrafish Mouse
regulation of nucleotide catabolic processGO:00308112050.017
regulation of cellular amino acid metabolic processGO:000652160.017
neuron differentiationGO:00301821380.017
Mouse Fly
regulation of gene silencing by mirnaGO:006096460.017
Worm
positive regulation of viral genome replicationGO:0045070150.016
maintenance of locationGO:00512351120.016
protein catabolic processGO:00301633250.016
rho protein signal transductionGO:0007266260.016
negative regulation of protein phosphorylationGO:00019331400.016
purine nucleoside triphosphate catabolic processGO:00091463920.016
post embryonic developmentGO:000979120.016
Mouse Worm
sister chromatid segregationGO:0000819540.016
positive regulation of cytokine productionGO:00018191670.016
Human
intracellular receptor signaling pathwayGO:00305221040.016
Human
cellular protein catabolic processGO:00442572610.016
protein processingGO:00164852260.016
single fertilizationGO:0007338110.015
negative regulation of phosphate metabolic processGO:00459362670.015
regulation of protein processingGO:00706131500.015
negative regulation of organelle organizationGO:00106391260.015
positive regulation of camp dependent protein kinase activityGO:200048140.015
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.015
regulation of protein targetingGO:1903533910.015
Human
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.015
reactive nitrogen species metabolic processGO:200105730.015
fertilizationGO:0009566120.015
g protein coupled receptor signaling pathwayGO:00071862070.015
microtubule based processGO:00070172100.014
Mouse
ribonucleoside catabolic processGO:00424544060.014
negative regulation of innate immune responseGO:0045824180.014
Human
cellular amine metabolic processGO:0044106410.014
regulation of nucleotide metabolic processGO:00061402690.014
regulation of microtubule based processGO:0032886740.014
small gtpase mediated signal transductionGO:0007264780.014
memoryGO:000761330.014
regulation of stem cell differentiationGO:2000736560.014
positive regulation of organelle organizationGO:00106381950.014
regulation of protein ubiquitinationGO:0031396950.014
cell divisionGO:00513011680.014
Mouse Fly
negative regulation of viral genome replicationGO:0045071350.014
chromatin remodelingGO:0006338550.014
guanosine containing compound metabolic processGO:19010682440.014
cellular response to oxidative stressGO:0034599850.014
positive regulation of hydrolase activityGO:00513453310.013
mitotic nuclear divisionGO:00070671190.013
glial cell migrationGO:000834740.013
metal ion transportGO:00300012720.013
purine ribonucleoside catabolic processGO:00461303980.013
regulation of protein localization to nucleusGO:1900180850.013
Human
regulation of stress activated mapk cascadeGO:0032872840.013
positive regulation of nucleotide metabolic processGO:00459812300.013
regulation of proteasomal protein catabolic processGO:0061136870.013
regulation of anatomical structure morphogenesisGO:00226032860.013
Mouse
enzyme linked receptor protein signaling pathwayGO:00071673030.013
regulation of hematopoietic progenitor cell differentiationGO:1901532240.013
negative regulation of proteolysisGO:00458611320.013
ribonucleoside monophosphate catabolic processGO:00091581580.013
male gamete generationGO:0048232220.013
mitotic cell cycleGO:00002783260.013
Fly
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
generation of neuronsGO:00486991520.013
Mouse Fly
neurotransmitter secretionGO:000726940.013
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.013
Mouse
ion transmembrane transportGO:00342203380.013
regulation of stem cell proliferationGO:0072091150.013
response to oxidative stressGO:00069791210.013
stem cell proliferationGO:0072089250.012
negative regulation of viral processGO:0048525660.012
matingGO:000761810.012
reactive oxygen species metabolic processGO:0072593750.012
dna recombinationGO:0006310770.012
modification dependent macromolecule catabolic processGO:00436322120.012
cell cell signalingGO:00072671550.012
mrna splicing via spliceosomeGO:0000398890.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
positive regulation of cell developmentGO:0010720920.012
Mouse
response to interferon alphaGO:0035455110.012
protein maturationGO:00516042330.012
regulation of chromosome organizationGO:00330441030.012
activation of mapkk activityGO:0000186180.012
regulation of cell divisionGO:00513021160.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
endocytosisGO:00068971590.012
osteoblast differentiationGO:0001649920.012
tissue morphogenesisGO:0048729960.012
Mouse
regulation of cellular protein catabolic processGO:1903362960.012
cell growthGO:00160491600.012
response to oxygen containing compoundGO:19017003690.012
positive regulation of proteolysisGO:00458621420.011
positive regulation of defense responseGO:0031349870.011
Human
motor neuron axon guidanceGO:000804520.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
positive regulation of gtpase activityGO:00435471660.011
cation transmembrane transportGO:00986552380.011
spermatogenesisGO:0007283220.011
brain developmentGO:0007420970.011
Zebrafish Mouse
regulation of cell migrationGO:00303342890.011
Human
response to nutrient levelsGO:0031667810.011
Fly
cellular response to starvationGO:0009267580.011
regulation of cell cycleGO:00517263930.011
Mouse
negative regulation of phosphorylationGO:00423261740.011
pattern specification processGO:0007389430.011
Fly
regulation of transcription by chromatin organizationGO:003440110.011
protein deacetylationGO:0006476380.011
cellular homeostasisGO:00197251960.011
chemokine productionGO:0032602320.011
regulation of purine nucleotide catabolic processGO:00331212050.011
cytokine productionGO:00018162470.011
Human
negative regulation of phosphorus metabolic processGO:00105632670.011
muscle structure developmentGO:0061061980.011
Mouse
immune response regulating signaling pathwayGO:0002764970.011
Human
cell part morphogenesisGO:00329901370.011
Mouse Fly
epithelium developmentGO:00604292270.011
Mouse
regulation of rna stabilityGO:0043487230.011
Mouse
regulation of reactive oxygen species biosynthetic processGO:190342630.011
gamete generationGO:0007276250.011
Fly
axon developmentGO:0061564340.010
positive regulation of immune system processGO:00026842830.010
Human
circadian behaviorGO:004851220.010
negative regulation of intracellular signal transductionGO:19025321830.010
Human
tripartite regional subdivisionGO:000735120.010
stress activated mapk cascadeGO:0051403930.010
response to cytokineGO:00340972320.010
tube morphogenesisGO:0035239950.010
Mouse
negative regulation of reactive oxygen species biosynthetic processGO:190342710.010
positive regulation of purine nucleotide metabolic processGO:19005442270.010
regulation of translational initiationGO:0006446240.010
divalent metal ion transportGO:00708381520.010
regulation of cell morphogenesisGO:00226041530.010
purine nucleoside triphosphate metabolic processGO:00091444120.010
ossificationGO:00015031210.010

DICER1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:3311860.018
nervous system diseaseDOID:8634310.018
cancerDOID:1621670.010
disease of cellular proliferationDOID:145661740.010
organ system cancerDOID:00506861640.009
endocrine system diseaseDOID:28260.002
respiratory system cancerDOID:0050615160.001
lung cancerDOID:1324160.001
thyroid gland diseaseDOID:50110.001