Homo sapiens

35 known processes

DR1

down-regulator of transcription 1, TBP-binding (negative cofactor 2)

(Aliases: NC2-BETA,NC2)

DR1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell developmentGO:00484683280.630
peptidyl lysine acetylationGO:00183941010.512
positive regulation of camp biosynthetic processGO:0030819350.474
small gtpase mediated signal transductionGO:0007264780.420
cellular macromolecular complex assemblyGO:00346223240.401
Fly
histone modificationGO:00165702510.371
protein modification by small protein conjugationGO:00324463420.302
translesion synthesisGO:001998580.296
generation of neuronsGO:00486991520.281
protein ubiquitinationGO:00165673140.268
nervous system developmentGO:00073992930.242
regulation of cellular component biogenesisGO:00440872810.238
internal protein amino acid acetylationGO:00064751010.228
protein catabolic processGO:00301633250.222
histone h3 acetylationGO:0043966450.204
actin filament based processGO:00300292240.201
protein dna complex subunit organizationGO:0071824800.199
Fly
anatomical structure formation involved in morphogenesisGO:00486462840.189
segmentationGO:003528240.187
proteolysis involved in cellular protein catabolic processGO:00516032440.187
ras protein signal transductionGO:0007265730.184
cell fate determinationGO:000170930.179
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112340.175
Fly
regulation of cytoskeleton organizationGO:00514931770.169
cellular protein complex assemblyGO:00436231880.158
actin cytoskeleton organizationGO:00300362070.152
histone acetylationGO:0016573930.148
protein polyubiquitinationGO:00002091100.144
modification dependent protein catabolic processGO:00199412090.143
protein dna complex assemblyGO:0065004640.141
Fly
chromatin organizationGO:00063253510.132
single organism cellular localizationGO:19025803320.131
organelle localizationGO:0051640840.125
negative regulation of protein metabolic processGO:00512483910.120
internal peptidyl lysine acetylationGO:0018393970.116
protein localization to organelleGO:00333652800.115
post embryonic developmentGO:000979120.115
adenylate cyclase activating g protein coupled receptor signaling pathwayGO:0007189180.114
cellular protein catabolic processGO:00442572610.112
regulation of cell developmentGO:00602841610.107
cellular macromolecule catabolic processGO:00442653800.102
regulation of transferase activityGO:00513383550.102
regulation of kinase activityGO:00435493140.101
camp biosynthetic processGO:0006171470.100
negative regulation of cellular protein metabolic processGO:00322693530.100
positive regulation of phosphorylationGO:00423273940.099
single organism carbohydrate metabolic processGO:00447231930.098
morphogenesis of embryonic epitheliumGO:001633140.090
protein acylationGO:00435431380.089
modification dependent macromolecule catabolic processGO:00436322120.089
carbohydrate derivative biosynthetic processGO:19011372070.087
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187430.086
negative regulation of programmed cell deathGO:00430693210.085
chromatin modificationGO:00165682980.084
dna replication independent nucleosome assemblyGO:0006336270.084
oxidation reduction processGO:00551143960.083
regulation of secretion by cellGO:19035301770.079
neuron differentiationGO:00301821380.079
dna replicationGO:00062601160.079
negative regulation of catabolic processGO:00098951040.078
cytoplasmic transportGO:00164823790.078
positive regulation of cyclase activityGO:0031281130.077
embryo developmentGO:00097901230.077
negative regulation of developmental processGO:00510932470.075
positive regulation of organelle organizationGO:00106381950.075
nuclear migrationGO:000709710.074
regulation of protein stabilityGO:0031647870.074
carbohydrate metabolic processGO:00059752070.069
regulation of cellular response to stressGO:00801352440.069
regulation of nucleoside metabolic processGO:00091182090.067
positive regulation of transferase activityGO:00513472270.067
organonitrogen compound biosynthetic processGO:19015662000.065
oocyte differentiationGO:000999420.064
glycoprotein biosynthetic processGO:0009101910.063
nuclear divisionGO:00002801280.063
cell divisionGO:00513011680.062
neuron projection developmentGO:00311751060.061
regulation of camp metabolic processGO:0030814520.060
positive regulation of purine nucleotide biosynthetic processGO:1900373380.058
ubiquitin dependent protein catabolic processGO:00065112060.058
regulation of small gtpase mediated signal transductionGO:00510561560.058
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188430.057
covalent chromatin modificationGO:00165692540.057
positive regulation of protein phosphorylationGO:00019343130.057
cell agingGO:0007569520.057
purine nucleoside catabolic processGO:00061523980.053
purine ribonucleoside triphosphate catabolic processGO:00092073910.053
neurogenesisGO:00220081690.053
amine metabolic processGO:0009308440.052
cyclic purine nucleotide metabolic processGO:0052652600.051
positive regulation of cellular component organizationGO:00511303760.051
purine ribonucleoside metabolic processGO:00461284370.051
ribonucleoside triphosphate metabolic processGO:00091994120.051
regulation of anatomical structure morphogenesisGO:00226032860.051
positive regulation of cytoskeleton organizationGO:0051495830.050
cellular response to dna damage stimulusGO:00069743790.049
oogenesisGO:004847720.049
regulation of cell cycle processGO:00105642660.048
regulation of protein localizationGO:00328802960.048
regulation of actin filament based processGO:00329701410.046
regulation of cell cycleGO:00517263930.046
erk1 and erk2 cascadeGO:00703711040.045
ribonucleotide biosynthetic processGO:0009260810.045
reproductive processGO:00224141060.045
guanosine containing compound metabolic processGO:19010682440.045
regulation of proteasomal protein catabolic processGO:0061136870.045
actin filament cappingGO:005169340.045
establishment or maintenance of microtubule cytoskeleton polarityGO:003095120.044
negative regulation of protein processingGO:00109551420.044
cellular component morphogenesisGO:00329893140.044
purine ribonucleotide catabolic processGO:00091544040.044
regulation of jnk cascadeGO:0046328730.043
secretionGO:00469032540.043
vesicle mediated transportGO:00161923710.043
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.041
peptidyl lysine modificationGO:00182051440.041
muscle structure developmentGO:0061061980.041
regulation of protein complex assemblyGO:00432541470.041
protein polymerizationGO:0051258710.041
positive regulation of protein kinase activityGO:00458601900.040
regulation of mapk cascadeGO:00434082620.040
proteasomal protein catabolic processGO:00104981760.040
regulation of anatomical structure sizeGO:00900661010.039
stem cell divisionGO:001714520.039
glycoprotein metabolic processGO:00091001100.039
mitotic cell cycle processGO:19030472860.039
photoreceptor cell differentiationGO:004653020.038
negative regulation of protein maturationGO:19033181420.038
negative regulation of apoptotic processGO:00430663160.038
cellular component assembly involved in morphogenesisGO:0010927730.038
positive regulation of cell differentiationGO:00455972110.037
macromolecule glycosylationGO:0043413630.037
regulation of gene expression epigeneticGO:0040029730.036
gtp metabolic processGO:00460392390.036
nucleosome assemblyGO:0006334500.036
dna replication independent nucleosome organizationGO:0034724270.036
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.036
regulation of protein catabolic processGO:00421761550.035
endomembrane system organizationGO:00102561960.035
asymmetric neuroblast divisionGO:005505910.035
g1 s transition of mitotic cell cycleGO:0000082780.035
protein glycosylationGO:0006486620.035
protein k48 linked ubiquitinationGO:0070936380.035
regulation of protein kinase activityGO:00458592890.035
ribonucleoside triphosphate catabolic processGO:00092033910.035
protein acetylationGO:00064731160.034
purine nucleotide biosynthetic processGO:0006164840.034
negative regulation of cellular component organizationGO:00511292350.033
oocyte developmentGO:004859910.033
organelle fissionGO:00482851490.033
neuron developmentGO:00486661130.033
positive regulation of camp metabolic processGO:0030816410.033
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.033
positive regulation of dendrite morphogenesisGO:005077530.033
regulation of secretionGO:00510461940.033
posttranscriptional regulation of gene expressionGO:00106082130.032
regulation of protein maturationGO:19033171500.032
camp metabolic processGO:0046058610.032
purine ribonucleoside catabolic processGO:00461303980.032
organophosphate biosynthetic processGO:00904071630.032
regulation of establishment of protein localizationGO:00702012420.032
reactive oxygen species metabolic processGO:0072593750.031
protein maturationGO:00516042330.030
glycosylationGO:0070085710.030
microtubule cytoskeleton organizationGO:00002261760.030
regulation of protein processingGO:00706131500.030
mitotic cell cycleGO:00002783260.030
mapk cascadeGO:00001652880.030
organelle assemblyGO:00709251760.030
negative regulation of cellular catabolic processGO:0031330830.030
nucleoside catabolic processGO:00091644080.029
nucleotide biosynthetic processGO:00091651090.029
positive regulation of mapk cascadeGO:00434101900.029
response to ionizing radiationGO:0010212650.029
signal transduction by phosphorylationGO:00230142970.029
regulation of cyclic nucleotide biosynthetic processGO:0030802490.029
regulation of proteolysisGO:00301622930.028
cyclic nucleotide metabolic processGO:0009187820.028
nitrogen compound transportGO:00717051910.028
purine nucleoside triphosphate catabolic processGO:00091463920.028
ribose phosphate biosynthetic processGO:0046390820.028
nucleoside phosphate catabolic processGO:19012924120.028
regulation of apoptotic signaling pathwayGO:20012331750.028
endocytosisGO:00068971590.028
purine ribonucleoside triphosphate metabolic processGO:00092054110.028
cyclic nucleotide biosynthetic processGO:0009190610.028
regulation of cellular ketone metabolic processGO:0010565500.027
positive regulation of cell projection organizationGO:0031346640.027
regulation of purine nucleotide biosynthetic processGO:1900371500.027
purine containing compound catabolic processGO:00725234110.027
cell growthGO:00160491600.027
regulation of map kinase activityGO:00434051080.027
establishment of organelle localizationGO:0051656590.027
postreplication repairGO:0006301120.027
negative regulation of rho gtpase activityGO:003425940.027
regulation of cellular component movementGO:00512703340.027
single organism reproductive processGO:0044702980.027
negative regulation of protein modification processGO:00314002000.027
regulation of nervous system developmentGO:0051960880.026
cytokinesisGO:0000910960.026
purine containing compound biosynthetic processGO:0072522880.026
regulation of cellular protein catabolic processGO:1903362960.026
secretion by cellGO:00329402260.025
cell part morphogenesisGO:00329901370.025
cell morphogenesisGO:00009022960.025
regulation of intracellular transportGO:00323861950.025
nucleus localizationGO:005164710.025
regulation of vesicle mediated transportGO:00606271300.025
membrane organizationGO:00610242920.025
regulation of actin cytoskeleton organizationGO:00329561160.025
epithelium developmentGO:00604292270.024
regulation of cyclic nucleotide metabolic processGO:0030799630.024
regulation of body fluid levelsGO:0050878990.024
establishment of nucleus localizationGO:004002310.024
negative regulation of cell proliferationGO:00082852280.024
regulation of transcription by chromatin organizationGO:003440110.024
determination of adult lifespanGO:000834020.024
actomyosin structure organizationGO:0031032590.024
regulation of purine nucleotide metabolic processGO:19005422640.024
jnk cascadeGO:0007254800.024
negative regulation of cell deathGO:00605483450.024
negative regulation of cell cycleGO:00457861930.023
positive regulation of cellular component biogenesisGO:00440891580.023
positive regulation of cell deathGO:00109422630.023
regulation of camp biosynthetic processGO:0030817450.023
regulation of locomotionGO:00400123290.023
nuclear transportGO:00511691790.023
g protein coupled receptor signaling pathwayGO:00071862070.023
positive regulation of nucleotide metabolic processGO:00459812300.023
dna repairGO:00062811980.022
regulation of purine nucleotide catabolic processGO:00331212050.022
negative regulation of protein catabolic processGO:0042177590.022
striated muscle cell differentiationGO:0051146430.022
positive regulation of cell developmentGO:0010720920.022
amine biosynthetic processGO:000930940.022
establishment of protein localization to organelleGO:00725941720.022
cellular amine metabolic processGO:0044106410.022
negative regulation of cell cycle phase transitionGO:1901988890.022
protein localization to nucleusGO:00345041360.022
regulation of cell projection organizationGO:00313441070.022
purine nucleoside triphosphate metabolic processGO:00091444120.022
rap protein signal transductionGO:003248670.022
negative regulation of phosphorus metabolic processGO:00105632670.021
protein processingGO:00164852260.021
nucleoside triphosphate metabolic processGO:00091414220.021
lipid biosynthetic processGO:00086101770.021
regulation of cellular amine metabolic processGO:0033238110.021
gtp catabolic processGO:00061842370.021
positive regulation of cyclic nucleotide metabolic processGO:0030801490.021
positive regulation of cell proliferationGO:00082843010.021
positive regulation of hydrolase activityGO:00513453310.021
nucleocytoplasmic transportGO:00069131760.021
stress activated protein kinase signaling cascadeGO:0031098940.021
nucleoside phosphate biosynthetic processGO:19012931090.021
protein k63 linked ubiquitinationGO:0070534310.021
single organism membrane organizationGO:00448022680.020
regulation of cell motilityGO:20001452990.020
cell projection morphogenesisGO:00488581290.020
growthGO:00400072020.020
reproductive structure developmentGO:0048608550.020
ribonucleotide catabolic processGO:00092614050.020
purine ribonucleotide biosynthetic processGO:0009152790.020
tube developmentGO:00352951250.020
guanosine containing compound catabolic processGO:19010692390.020
establishment or maintenance of cytoskeleton polarityGO:003095230.020
myosin filament assemblyGO:003103420.020
regulation of neurogenesisGO:0050767820.020
response to radiationGO:00093141510.020
somitogenesisGO:000175620.020
developmental process involved in reproductionGO:0003006660.020
positive regulation of purine nucleotide metabolic processGO:19005442270.019
glycosyl compound catabolic processGO:19016584130.019
anterior posterior axis specificationGO:000994820.019
positive regulation of cyclic nucleotide biosynthetic processGO:0030804380.019
cellular amino acid metabolic processGO:00065201160.019
positive regulation of nucleotide biosynthetic processGO:0030810380.019
regulation of nucleotide metabolic processGO:00061402690.019
chordate embryonic developmentGO:0043009340.019
mitotic cell cycle checkpointGO:0007093680.019
negative regulation of hydrolase activityGO:00513461820.018
cell cycle arrestGO:0007050710.018
response to starvationGO:0042594590.018
positive regulation of nucleoside metabolic processGO:00459791860.018
regulation of growthGO:00400081650.018
macromolecule methylationGO:0043414970.018
negative regulation of cell cycle processGO:00109481210.018
protein import into nucleusGO:00066061040.018
negative regulation of kinase activityGO:00336731060.018
gene silencingGO:0016458490.018
regulation of protein transportGO:00512232130.018
regulation of protein serine threonine kinase activityGO:00719001790.018
protein alkylationGO:0008213740.017
positive regulation of cellular catabolic processGO:00313312840.017
nucleoside triphosphate catabolic processGO:00091433940.017
hormone transportGO:0009914680.017
female gamete generationGO:000729220.017
adult locomotory behaviorGO:000834410.017
regulation of nucleotide catabolic processGO:00308112050.017
cell projection organizationGO:00300302520.017
apoptotic signaling pathwayGO:00971902680.017
regulation of ras protein signal transductionGO:00465781550.017
neuromuscular junction developmentGO:000752830.017
blood vessel developmentGO:00015681720.017
rna splicingGO:00083801310.017
negative regulation of proteolysisGO:00458611320.017
regulation of meiotic cell cycleGO:005144540.017
regulation of protein polymerizationGO:0032271630.017
muscle cell differentiationGO:0042692630.017
cell projection assemblyGO:00300311260.017
locomotory behaviorGO:000762610.017
meiotic chromosome segregationGO:004513240.017
insulin secretionGO:0030073390.017
positive regulation of locomotionGO:00400171860.016
regulation of stress activated protein kinase signaling cascadeGO:0070302850.016
positive regulation of nervous system developmentGO:0051962540.016
negative regulation of phosphate metabolic processGO:00459362670.016
positive regulation of gtpase activityGO:00435471660.016
dephosphorylationGO:00163112090.016
regulation of cell differentiationGO:00455953930.016
nuclear importGO:00511701060.016
cell adhesionGO:00071553250.016
negative regulation of organelle organizationGO:00106391260.016
positive regulation of developmental processGO:00510943140.016
positive regulation of neuron differentiationGO:0045666400.016
regulation of protein modification by small protein conjugation or removalGO:19033201070.016
cell morphogenesis involved in differentiationGO:00009041440.016
positive regulation of map kinase activityGO:0043406800.016
dna templated transcription initiationGO:0006352350.016
Fly
regulation of mitotic cell cycle phase transitionGO:19019901180.015
regulation of chromatin modificationGO:1903308510.015
response to fungusGO:000962040.015
cell cycle phase transitionGO:00447701730.015
ribonucleoside catabolic processGO:00424544060.015
regulation of mitotic cell cycleGO:00073461890.015
activation of adenylate cyclase activityGO:000719050.015
regulation of reactive oxygen species metabolic processGO:2000377410.015
reproductionGO:0000003630.015
cellular response to abiotic stimulusGO:00712141170.015
response to oxygen containing compoundGO:19017003690.015
regulation of cyclase activityGO:0031279190.015
negative regulation of muscle tissue developmentGO:1901862110.015
negative regulation of transferase activityGO:00513481240.015
protein targetingGO:00066051870.015
compound eye developmentGO:004874910.015
establishment or maintenance of apical basal cell polarityGO:003508820.015
vasculature developmentGO:00019441810.015
negative regulation of locomotionGO:00400131180.015
negative regulation of cell differentiationGO:00455961710.015
macroautophagyGO:0016236390.015
embryo development ending in birth or egg hatchingGO:0009792340.014
protein targeting to nucleusGO:00447441040.014
asymmetric stem cell divisionGO:009872210.014
positive regulation of cell migrationGO:00303351720.014
regulation of protein ubiquitinationGO:0031396950.014
regulation of neuron projection developmentGO:0010975570.014
regulation of meiosisGO:004002030.014
regulation of chromosome organizationGO:00330441030.014
pattern specification processGO:0007389430.014
blastocyst developmentGO:000182430.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
Fly
protein n linked glycosylation via asparagineGO:0018279100.014
protein dephosphorylationGO:0006470810.014
microtubule based processGO:00070172100.014
protein stabilizationGO:0050821640.014
establishment or maintenance of cell polarityGO:0007163310.014
single organismal cell cell adhesionGO:00163371480.014
replicative cell agingGO:000130230.014
regulation of oocyte developmentGO:006028110.014
anterior posterior axis specification embryoGO:000859520.014
camp mediated signalingGO:0019933230.013
histone exchangeGO:004348630.013
regulation of nucleotide biosynthetic processGO:0030808500.013
adenylate cyclase activating adrenergic receptor signaling pathwayGO:007188030.013
multi organism reproductive processGO:0044703540.013
myosin filament organizationGO:003103320.013
negative regulation of protein phosphorylationGO:00019331400.013
establishment of blood brain barrierGO:006085610.013
dna biosynthetic processGO:0071897400.013
regulation of cellular amino acid metabolic processGO:000652160.013
regulation of ras gtpase activityGO:00323181280.013
positive regulation of rap gtpase activityGO:003285480.013
reproductive system developmentGO:0061458560.013
cilium morphogenesisGO:0060271750.013
nucleosome organizationGO:0034728660.013
Fly
regulation of cell morphogenesisGO:00226041530.013
positive regulation of catabolic processGO:00098963100.013
rna interferenceGO:001624640.013
response to other organismGO:00517072610.013
myoblast fusionGO:000752010.013
purine nucleotide catabolic processGO:00061954050.013
cellular ketone metabolic processGO:0042180800.013
somatic stem cell divisionGO:004810310.013
defense responseGO:00069523150.013
intracellular protein transportGO:00068862700.012
negative regulation of catalytic activityGO:00430863350.012
positive regulation of nucleotide catabolic processGO:00308131850.012
exocytosisGO:0006887710.012
circulatory system developmentGO:00723592620.012
cardiovascular system developmentGO:00723582620.012
cell activationGO:00017752130.012
positive regulation of protein complex assemblyGO:0031334860.012
regulation of neuron differentiationGO:0045664700.012
mrna metabolic processGO:00160711750.012
negative regulation of phosphorylationGO:00423261740.012
regulation of actin polymerization or depolymerizationGO:0008064560.012
stem cell differentiationGO:0048863930.012
regulation of peptide transportGO:0090087620.011
negative regulation of protein kinase activityGO:0006469980.011
positive regulation of cell cycle processGO:00900681060.011
regulation of stress activated mapk cascadeGO:0032872840.011
er associated ubiquitin dependent protein catabolic processGO:0030433310.011
regulation of cell migrationGO:00303342890.011
regulation of exocytosisGO:0017157460.011
regionalizationGO:0003002290.011
regulation of erk1 and erk2 cascadeGO:0070372990.011
regulation of actin filament polymerizationGO:0030833500.011
positive regulation of dendritic spine developmentGO:006099920.011
methylationGO:00322591060.011
regulation of gtp catabolic processGO:00331241800.011
heterochromatin organizationGO:007082860.011
regulation of protein secretionGO:0050708860.010
multicellular organismal agingGO:001025930.010
innate immune responseGO:00450871780.010
centromere complex assemblyGO:0034508100.010
developmental maturationGO:0021700280.010
rna processingGO:00063962550.010
intracellular mrna localizationGO:000829810.010
negative regulation of nucleotide catabolic processGO:0030812160.010
negative regulation of mitotic cell cycleGO:00459301020.010
immune responseGO:00069553070.010
gliogenesisGO:0042063210.010
single fertilizationGO:0007338110.010
peptide hormone secretionGO:0030072500.010
spermatid differentiationGO:004851540.010
heart developmentGO:0007507950.010
positive regulation of secretionGO:00510471160.010
single organism cell adhesionGO:00986021790.010
regulation of gtpase activityGO:00430871800.010

DR1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
gastrointestinal system cancerDOID:3119520.036
disease of cellular proliferationDOID:145661740.036
cancerDOID:1621670.036
organ system cancerDOID:00506861640.036
sensory system diseaseDOID:00501552030.019
nervous system diseaseDOID:8634310.019
eye and adnexa diseaseDOID:14921500.019