Homo sapiens

257 known processes

TERF1

telomeric repeat binding factor (NIMA-interacting) 1

(Aliases: FLJ41416,TRBF1,TRF,TRF1,t-TRF1,hTRF1-AS,PIN2)

TERF1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
telomere maintenance via telomere lengtheningGO:001083391.000
regulation of telomere maintenance via telomeraseGO:003221061.000
protein localization to chromosome telomeric regionGO:007019861.000
Human
regulation of telomere maintenanceGO:0032204130.999
positive regulation of telomere maintenanceGO:003220640.999
rna dependent dna replicationGO:0006278160.996
anatomical structure homeostasisGO:00602491000.994
positive regulation of cellular component organizationGO:00511303760.976
regulation of dna metabolic processGO:00510521530.956
dna replicationGO:00062601160.948
positive regulation of canonical wnt signaling pathwayGO:0090263330.909
telomere organizationGO:0032200330.884
glycoprotein biosynthetic processGO:0009101910.874
positive regulation of dna replicationGO:0045740350.863
telomere maintenanceGO:0000723320.856
glycoprotein metabolic processGO:00091001100.844
meiotic chromosome segregationGO:004513240.818
macromolecule glycosylationGO:0043413630.757
wnt signaling pathwayGO:00160551560.741
positive regulation of dna metabolic processGO:0051054730.725
regulation of cellular component biogenesisGO:00440872810.709
negative regulation of dna replicationGO:0008156290.702
positive regulation of chromosome organizationGO:2001252410.692
protein auto adp ribosylationGO:007021340.686
carbohydrate derivative biosynthetic processGO:19011372070.685
cellular macromolecular complex assemblyGO:00346223240.651
positive regulation of homeostatic processGO:0032846470.651
telomere maintenance via telomeraseGO:000700480.649
single organism carbohydrate metabolic processGO:00447231930.633
positive regulation of wnt signaling pathwayGO:0030177540.616
carbohydrate metabolic processGO:00059752070.595
regulation of canonical wnt signaling pathwayGO:0060828880.592
protein glycosylationGO:0006486620.562
protein localization to chromosomeGO:0034502300.545
Human
sister chromatid segregationGO:0000819540.542
mitotic sister chromatid segregationGO:0000070530.482
protein adp ribosylationGO:000647190.480
protein localization to organelleGO:00333652800.453
Human
negative regulation of cellular component organizationGO:00511292350.448
mitotic cell cycleGO:00002783260.435
negative regulation of programmed cell deathGO:00430693210.426
positive regulation of cellular component biogenesisGO:00440891580.409
peptidyl serine modificationGO:00182091060.405
cellular protein complex assemblyGO:00436231880.394
negative regulation of telomere maintenanceGO:003220590.389
negative regulation of dna metabolic processGO:0051053570.389
negative regulation of developmental processGO:00510932470.386
protein polymerizationGO:0051258710.381
regulation of dna replicationGO:0006275680.376
microtubule polymerization or depolymerizationGO:0031109370.373
mitotic cell cycle processGO:19030472860.359
organelle fissionGO:00482851490.313
negative regulation of bindingGO:0051100570.277
mitotic nuclear divisionGO:00070671190.276
protein polyubiquitinationGO:00002091100.253
modification dependent macromolecule catabolic processGO:00436322120.240
mitotic cell cycle phase transitionGO:00447721620.237
peptidyl serine phosphorylationGO:00181051010.234
positive regulation of organelle organizationGO:00106381950.228
regulation of chromosome organizationGO:00330441030.225
peptidyl threonine phosphorylationGO:0018107410.222
peptidyl threonine modificationGO:0018210450.215
canonical wnt signaling pathwayGO:00600701160.215
microtubule polymerizationGO:0046785180.203
negative regulation of cell proliferationGO:00082852280.187
cell cycle phase transitionGO:00447701730.183
negative regulation of protein metabolic processGO:00512483910.172
ubiquitin dependent protein catabolic processGO:00065112060.171
chromosome segregationGO:00070591140.169
organic hydroxy compound metabolic processGO:19016151470.162
negative regulation of telomere maintenance via telomeraseGO:003221150.161
cell cycle g2 m phase transitionGO:0044839430.161
cellular response to dna damage stimulusGO:00069743790.160
Human
metaphase anaphase transition of cell cycleGO:0044784210.154
regulation of microtubule based processGO:0032886740.154
g2 m transition of mitotic cell cycleGO:0000086410.148
proteolysis involved in cellular protein catabolic processGO:00516032440.144
modification dependent protein catabolic processGO:00199412090.143
meiosis iGO:000712740.143
negative regulation of multicellular organismal processGO:00512413170.143
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.137
negative regulation of epithelial cell proliferationGO:0050680480.134
protein poly adp ribosylationGO:007021230.128
regulation of cell cycle phase transitionGO:19019871260.128
positive regulation of protein bindingGO:0032092240.125
organelle localizationGO:0051640840.121
positive regulation of protein complex assemblyGO:0031334860.115
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.114
regulation of protein bindingGO:0043393660.111
response to abiotic stimulusGO:00096283360.111
regulation of protein modification by small protein conjugation or removalGO:19033201070.110
regulation of cell cycleGO:00517263930.109
negative regulation of cell deathGO:00605483450.107
negative regulation of cell cycle processGO:00109481210.103
chromatin organizationGO:00063253510.098
regulation of transferase activityGO:00513383550.095
regulation of epithelial cell proliferationGO:00506781130.095
glycosylationGO:0070085710.087
neuromuscular junction developmentGO:000752830.086
cellular macromolecule catabolic processGO:00442653800.086
regulation of protein complex assemblyGO:00432541470.085
protein homooligomerizationGO:00512601000.083
dna packagingGO:0006323770.082
post embryonic developmentGO:000979120.081
segmentationGO:003528240.081
apoptotic signaling pathwayGO:00971902680.081
regulation of wnt signaling pathwayGO:00301111230.078
locomotory behaviorGO:000762610.077
epithelial cell proliferationGO:00506731280.073
oocyte developmentGO:004859910.071
negative regulation of organelle organizationGO:00106391260.070
oocyte differentiationGO:000999420.070
dna conformation changeGO:00711031130.069
negative regulation of apoptotic processGO:00430663160.064
regulation of bindingGO:00510981110.064
telomere cappingGO:001623350.064
Human
regulation of proteasomal protein catabolic processGO:0061136870.063
determination of adult lifespanGO:000834020.063
positive regulation of protein polymerizationGO:0032273450.063
photoreceptor cell maintenanceGO:0045494130.062
regulation of mitotic sister chromatid segregationGO:0033047270.061
dna integrity checkpointGO:0031570710.060
cellular ketone metabolic processGO:0042180800.060
regulation of kinase activityGO:00435493140.057
lipid metabolic processGO:00066293810.055
multicellular organismal agingGO:001025930.053
regulation of homeostatic processGO:00328441210.053
protein dna complex assemblyGO:0065004640.052
protein catabolic processGO:00301633250.052
growthGO:00400072020.052
negative regulation of cell cycle phase transitionGO:1901988890.052
positive regulation of cell deathGO:00109422630.051
regulation of glycoprotein metabolic processGO:1903018190.051
cell agingGO:0007569520.050
negative regulation of protein catabolic processGO:0042177590.050
negative regulation of chromosome organizationGO:2001251480.050
negative regulation of cell cycleGO:00457861930.048
membrane organizationGO:00610242920.048
negative regulation of mitotic cell cycleGO:00459301020.048
negative regulation of cellular protein metabolic processGO:00322693530.047
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.046
cellular amine metabolic processGO:0044106410.046
protein modification by small protein conjugationGO:00324463420.046
cellular response to lipidGO:00713961270.044
reciprocal meiotic recombinationGO:000713140.044
regulation of growthGO:00400081650.044
single organism cellular localizationGO:19025803320.044
negative regulation of dna bindingGO:0043392180.043
nuclear divisionGO:00002801280.043
somitogenesisGO:000175620.042
dna double strand break processingGO:0000729100.042
receptor mediated endocytosisGO:0006898840.040
head developmentGO:00603221080.040
positive regulation of cell differentiationGO:00455972110.039
negative regulation of proteasomal protein catabolic processGO:1901799320.039
cellular protein catabolic processGO:00442572610.039
regulation of protein ubiquitinationGO:0031396950.039
oogenesisGO:004847720.039
regulation of sequence specific dna binding transcription factor activityGO:00510902110.039
regulation of protein processingGO:00706131500.037
negative regulation of actin nucleationGO:005112630.037
response to radiationGO:00093141510.037
response to oxygen containing compoundGO:19017003690.036
intrinsic apoptotic signaling pathwayGO:00971931270.035
agingGO:0007568660.035
negative regulation of cellular protein catabolic processGO:1903363380.035
actin cytoskeleton organizationGO:00300362070.035
negative regulation of phosphate metabolic processGO:00459362670.035
negative regulation of immune system processGO:00026831360.034
negative regulation of cytoskeleton organizationGO:0051494450.033
endocytosisGO:00068971590.033
cell type specific apoptotic processGO:00972851250.033
reciprocal dna recombinationGO:003582540.033
regulation of cell differentiationGO:00455953930.033
regulation of microtubule polymerization or depolymerizationGO:0031110270.032
female gamete generationGO:000729220.032
negative regulation of catabolic processGO:00098951040.032
regulation of chromosome segregationGO:0051983440.031
stem cell differentiationGO:0048863930.031
cellular carbohydrate metabolic processGO:0044262840.030
positive regulation of programmed cell deathGO:00430682490.030
negative regulation of cell differentiationGO:00455961710.030
regulation of cellular carbohydrate metabolic processGO:0010675470.029
negative regulation of homeostatic processGO:0032845590.029
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.028
glycerophospholipid metabolic processGO:0006650840.028
glycerolipid biosynthetic processGO:0045017510.028
dna catabolic processGO:0006308490.028
regulation of locomotionGO:00400123290.028
regulation of cellular component movementGO:00512703340.028
negative regulation of cellular catabolic processGO:0031330830.028
cellular lipid metabolic processGO:00442553030.028
negative regulation of protein complex assemblyGO:0031333430.028
protein processingGO:00164852260.027
lipid biosynthetic processGO:00086101770.027
regulation of anatomical structure morphogenesisGO:00226032860.027
cellular response to ionizing radiationGO:0071479320.027
positive regulation of telomere maintenance via telomeraseGO:003221220.027
phospholipid metabolic processGO:0006644990.026
regulation of response to dna damage stimulusGO:2001020940.026
negative regulation of protein polymerizationGO:0032272160.026
embryo developmentGO:00097901230.025
proteasomal protein catabolic processGO:00104981760.025
purine containing compound catabolic processGO:00725234110.025
associative learningGO:000830610.024
protein localization to membraneGO:00726571600.024
positive regulation of cell cycleGO:00457871400.024
negative regulation of cell migrationGO:00303361020.024
negative regulation of apoptotic signaling pathwayGO:2001234970.024
plasma membrane organizationGO:00070091150.024
leukocyte differentiationGO:0002521980.023
regulation of lymphocyte proliferationGO:0050670640.023
regulation of carbohydrate metabolic processGO:0006109540.023
cellular response to abiotic stimulusGO:00712141170.023
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.023
protein ubiquitinationGO:00165673140.023
glycerolipid metabolic processGO:00464861070.023
brain developmentGO:0007420970.022
dna damage checkpointGO:0000077680.022
cellular amino acid metabolic processGO:00065201160.022
intracellular protein transportGO:00068862700.022
response to organic cyclic compoundGO:00140702040.022
regulation of cell cycle processGO:00105642660.022
negative regulation of mitotic cell cycle phase transitionGO:1901991850.021
positive regulation of cytoskeleton organizationGO:0051495830.021
dna damage induced protein phosphorylationGO:000697550.021
protein maturationGO:00516042330.021
negative regulation of cellular component movementGO:00512711060.021
phosphatidylinositol 3 phosphate biosynthetic processGO:003609230.021
organophosphate biosynthetic processGO:00904071630.020
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.020
immune effector processGO:00022521590.020
positive regulation of cellular amino acid metabolic processGO:004576430.020
regulation of mitotic cell cycleGO:00073461890.020
cytokinesisGO:0000910960.020
regulation of developmental growthGO:0048638300.020
regulation of metaphase anaphase transition of cell cycleGO:1902099260.020
response to fungusGO:000962040.020
regulation of cellular response to stressGO:00801352440.020
negative regulation of glycoprotein metabolic processGO:190301980.019
protein dna complex subunit organizationGO:0071824800.019
positive regulation of cell cycle processGO:00900681060.019
regulation of dna endoreduplicationGO:003287550.019
response to lipidGO:00339932060.019
positive regulation of cellular amine metabolic processGO:003324070.018
double strand break repairGO:00063021010.018
mapk cascadeGO:00001652880.018
regulation of protein maturationGO:19033171500.018
regulation of cellular ketone metabolic processGO:0010565500.018
cell fate determinationGO:000170930.018
microtubule based processGO:00070172100.017
mrna catabolic processGO:0006402560.017
covalent chromatin modificationGO:00165692540.017
compound eye developmentGO:004874910.017
organelle assemblyGO:00709251760.017
neurological system processGO:00508771630.017
negative regulation of protein modification processGO:00314002000.017
response to nitrogen compoundGO:19016981840.017
proteasome assemblyGO:004324870.016
negative regulation of cell developmentGO:0010721480.016
regulation of dna bindingGO:0051101370.016
positive regulation of cell developmentGO:0010720920.016
positive regulation of bindingGO:0051099450.016
positive regulation of protein phosphorylationGO:00019343130.016
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.016
negative regulation of cell motilityGO:20001461040.016
regulation of neural precursor cell proliferationGO:200017740.016
negative regulation of protein maturationGO:19033181420.016
central nervous system developmentGO:00074171230.016
ossificationGO:00015031210.016
positive regulation of cell projection organizationGO:0031346640.016
mitotic sister chromatid separationGO:0051306180.016
cell divisionGO:00513011680.016
hematopoietic or lymphoid organ developmentGO:00485341860.016
nucleosome assemblyGO:0006334500.016
cell cycle checkpointGO:00000751170.016
angiogenesisGO:00015251470.015
secretionGO:00469032540.015
regulation of microtubule polymerizationGO:0031113120.015
regulation of phagocytosis engulfmentGO:006009920.015
positive regulation of cellular catabolic processGO:00313312840.015
regulation of cellular amine metabolic processGO:0033238110.015
regulation of mitotic metaphase anaphase transitionGO:0030071260.015
anatomical structure formation involved in morphogenesisGO:00486462840.015
neuron deathGO:0070997650.015
regulation of cellular amino acid metabolic processGO:000652160.015
regulation of protein kinase activityGO:00458592890.015
vesicle mediated transportGO:00161923710.015
recombinational repairGO:0000725500.014
positive regulation of developmental processGO:00510943140.014
negative regulation of growthGO:0045926970.014
positive regulation of apoptotic processGO:00430652460.014
regulation of establishment of protein localizationGO:00702012420.014
positive regulation of phosphorylationGO:00423273940.014
nucleocytoplasmic transportGO:00069131760.014
nucleotide catabolic processGO:00091664080.014
negative regulation of locomotionGO:00400131180.014
regulation of mitotic cell cycle phase transitionGO:19019901180.014
immune system developmentGO:00025201950.014
actin filament based processGO:00300292240.014
adult locomotory behaviorGO:000834410.013
oxidation reduction processGO:00551143960.013
positive regulation of transportGO:00510503360.013
cellular response to external stimulusGO:00714961110.013
regulation of nervous system developmentGO:0051960880.013
cell morphogenesisGO:00009022960.013
response to external biotic stimulusGO:00432072610.013
developmental growthGO:0048589480.013
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.013
regulation of cellular protein catabolic processGO:1903362960.013
negative regulation of glycoprotein biosynthetic processGO:001056150.013
gtp metabolic processGO:00460392390.013
innate immune responseGO:00450871780.013
engulfment of apoptotic cellGO:004365220.013
centrosome organizationGO:0051297580.013
regulation of cytoplasmic transportGO:19036491490.012
ribosomal protein import into nucleusGO:000661020.012
positive regulation of neurogenesisGO:0050769490.012
negative regulation of phosphorus metabolic processGO:00105632670.012
cellular component disassemblyGO:0022411920.012
regulation of cell migrationGO:00303342890.012
purine nucleoside triphosphate metabolic processGO:00091444120.012
developmental growth involved in morphogenesisGO:0060560230.012
negative regulation of carbohydrate metabolic processGO:0045912200.012
regulation of cell motilityGO:20001452990.012
response to caffeineGO:003100030.012
i kappab kinase nf kappab signalingGO:00072491660.012
regulation of gene expression epigeneticGO:0040029730.012
rna catabolic processGO:0006401710.012
ameboidal type cell migrationGO:00016671350.012
response to gamma radiationGO:0010332140.012
meiotic cell cycle processGO:190304680.012
negative regulation of b cell activationGO:005086960.011
osteoblast differentiationGO:0001649920.011
nervous system developmentGO:00073992930.011
protein autophosphorylationGO:00467771230.011
negative regulation of protein processingGO:00109551420.011
tissue homeostasisGO:0001894630.011
signal transduction by phosphorylationGO:00230142970.011
cellular response to radiationGO:0071478650.011
fatty acid derivative metabolic processGO:1901568350.011
reproductive structure developmentGO:0048608550.011
epithelium migrationGO:00901321190.011
cell cycle arrestGO:0007050710.011
protein targeting to nucleusGO:00447441040.011
regulation of epithelial cell migrationGO:0010632930.011
circadian sleep wake cycle sleepGO:005080220.011
autophagyGO:0006914880.011
macromolecular complex disassemblyGO:0032984600.011
ribonucleotide catabolic processGO:00092614050.011
purine ribonucleoside metabolic processGO:00461284370.011
positive regulation of cell proliferationGO:00082843010.011
signal transduction involved in dna damage checkpointGO:0072422150.011
regulation of proteolysisGO:00301622930.010
circadian behaviorGO:004851220.010
glycerophospholipid biosynthetic processGO:0046474400.010
hemopoiesisGO:00300971800.010
system processGO:00030083490.010
regulation of mitotic sister chromatid separationGO:0010965270.010
neurogenesisGO:00220081690.010
establishment of protein localization to plasma membraneGO:0090002680.010
sensory perceptionGO:00076001030.010
cell growthGO:00160491600.010
microtubule cytoskeleton organizationGO:00002261760.010
regulation of peptidyl serine phosphorylationGO:0033135500.010

TERF1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.088
disease of cellular proliferationDOID:145661740.088
organ system cancerDOID:00506861640.027
central nervous system diseaseDOID:3311860.014
nervous system diseaseDOID:8634310.014