Homo sapiens

62 known processes

DPYD

dihydropyrimidine dehydrogenase

(Aliases: MGC132008,DPD,DHPDHASE,MGC70799,DHP)

DPYD biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amine metabolic processGO:0044106410.091
purine ribonucleoside metabolic processGO:00461284370.083
positive regulation of hydrolase activityGO:00513453310.078
regulation of cellular amine metabolic processGO:0033238110.078
positive regulation of catabolic processGO:00098963100.077
positive regulation of nucleotide metabolic processGO:00459812300.075
cellular amino acid metabolic processGO:00065201160.074
positive regulation of transportGO:00510503360.074
positive regulation of cellular catabolic processGO:00313312840.072
response to external biotic stimulusGO:00432072610.071
purine nucleoside triphosphate catabolic processGO:00091463920.069
amine metabolic processGO:0009308440.069
organophosphate catabolic processGO:00464344300.069
positive regulation of purine nucleotide metabolic processGO:19005442270.069
post embryonic developmentGO:000979120.068
regulation of purine nucleotide metabolic processGO:19005422640.067
positive regulation of immune system processGO:00026842830.067
purine nucleoside triphosphate metabolic processGO:00091444120.066
purine containing compound catabolic processGO:00725234110.066
regulation of cellular ketone metabolic processGO:0010565500.065
positive regulation of phosphorylationGO:00423273940.065
cellular ketone metabolic processGO:0042180800.065
glycosyl compound catabolic processGO:19016584130.064
regulation of nucleotide metabolic processGO:00061402690.063
defense responseGO:00069523150.061
purine ribonucleoside catabolic processGO:00461303980.060
nucleotide catabolic processGO:00091664080.058
nucleoside catabolic processGO:00091644080.057
regulation of cellular amino acid metabolic processGO:000652160.057
regulation of nucleoside metabolic processGO:00091182090.057
positive regulation of nucleotide catabolic processGO:00308131850.056
ribonucleoside triphosphate metabolic processGO:00091994120.055
negative regulation of protein metabolic processGO:00512483910.054
purine nucleotide catabolic processGO:00061954050.054
regulation of protein localizationGO:00328802960.053
ribonucleoside catabolic processGO:00424544060.053
ribonucleoside triphosphate catabolic processGO:00092033910.053
nucleoside triphosphate catabolic processGO:00091433940.050
purine nucleoside catabolic processGO:00061523980.050
purine ribonucleotide catabolic processGO:00091544040.050
lipid metabolic processGO:00066293810.049
positive regulation of cellular amino acid metabolic processGO:004576430.048
purine ribonucleoside triphosphate catabolic processGO:00092073910.048
positive regulation of cellular component organizationGO:00511303760.046
multicellular organismal agingGO:001025930.046
response to oxygen containing compoundGO:19017003690.046
protein maturationGO:00516042330.046
response to other organismGO:00517072610.046
regulation of establishment of protein localizationGO:00702012420.045
regulation of nucleotide catabolic processGO:00308112050.045
gtp metabolic processGO:00460392390.045
ras protein signal transductionGO:0007265730.044
gtp catabolic processGO:00061842370.044
innate immune responseGO:00450871780.043
ribonucleotide catabolic processGO:00092614050.043
positive regulation of cellular amine metabolic processGO:003324070.043
guanosine containing compound metabolic processGO:19010682440.043
purine ribonucleoside triphosphate metabolic processGO:00092054110.043
nucleoside triphosphate metabolic processGO:00091414220.042
protein processingGO:00164852260.042
determination of adult lifespanGO:000834020.041
nucleoside phosphate catabolic processGO:19012924120.041
regulation of peptidase activityGO:00525471800.041
response to cytokineGO:00340972320.040
regulation of transferase activityGO:00513383550.040
negative regulation of catalytic activityGO:00430863350.040
positive regulation of purine nucleotide catabolic processGO:00331231850.039
carbohydrate derivative biosynthetic processGO:19011372070.039
cell morphogenesisGO:00009022960.039
negative regulation of cellular protein metabolic processGO:00322693530.039
immune responseGO:00069553070.039
regulation of gtp catabolic processGO:00331241800.039
negative regulation of protein maturationGO:19033181420.038
membrane organizationGO:00610242920.038
positive regulation of nucleoside metabolic processGO:00459791860.038
positive regulation of immune responseGO:00507781590.038
regulation of protein transportGO:00512232130.038
regulation of proteolysisGO:00301622930.038
female gamete generationGO:000729220.038
small gtpase mediated signal transductionGO:0007264780.038
regulation of immune responseGO:00507762010.037
guanosine containing compound catabolic processGO:19010692390.037
apoptotic signaling pathwayGO:00971902680.036
oogenesisGO:004847720.036
regulation of purine nucleotide catabolic processGO:00331212050.036
small molecule biosynthetic processGO:00442831570.036
regulation of locomotionGO:00400123290.035
regulation of cell cycleGO:00517263930.035
biological adhesionGO:00226103310.035
cell developmentGO:00484683280.035
organonitrogen compound biosynthetic processGO:19015662000.035
response to biotic stimulusGO:00096072760.035
regulation of response to external stimulusGO:00321012220.034
activation of immune responseGO:00022531140.033
regulation of secretionGO:00510461940.033
positive regulation of gtpase activityGO:00435471660.033
cellular lipid metabolic processGO:00442553030.032
cell projection organizationGO:00300302520.032
segmentationGO:003528240.032
leukocyte activationGO:00453211640.032
vesicle mediated transportGO:00161923710.031
regulation of cell differentiationGO:00455953930.031
signal transduction by phosphorylationGO:00230142970.031
cell adhesionGO:00071553250.030
regulation of kinase activityGO:00435493140.030
regenerationGO:003109940.030
regulation of cytokine productionGO:00018172320.030
regulation of cellular component biogenesisGO:00440872810.030
positive regulation of protein transportGO:00512221350.030
regulation of endopeptidase activityGO:00525481700.030
positive regulation of protein phosphorylationGO:00019343130.030
negative regulation of phosphate metabolic processGO:00459362670.030
cellular macromolecule catabolic processGO:00442653800.030
cellular response to endogenous stimulusGO:00714953360.030
regulation of gtpase activityGO:00430871800.029
immune effector processGO:00022521590.029
mapk cascadeGO:00001652880.029
cellular response to oxygen containing compoundGO:19017012760.029
cytokine productionGO:00018162470.029
positive regulation of apoptotic processGO:00430652460.028
positive regulation of cytokine productionGO:00018191670.028
lipid biosynthetic processGO:00086101770.028
regulation of defense responseGO:00313471540.028
cardiovascular system developmentGO:00723582620.028
negative regulation of hydrolase activityGO:00513461820.027
regulation of cell cycle processGO:00105642660.027
memoryGO:000761330.027
positive regulation of protein kinase activityGO:00458601900.027
actin filament based processGO:00300292240.027
cytoplasmic transportGO:00164823790.027
positive regulation of developmental processGO:00510943140.026
regulation of mapk cascadeGO:00434082620.026
protein catabolic processGO:00301633250.026
regulation of protein maturationGO:19033171500.026
system processGO:00030083490.026
negative regulation of phosphorus metabolic processGO:00105632670.026
regulation of sequence specific dna binding transcription factor activityGO:00510902110.026
locomotory behaviorGO:000762610.026
cell activationGO:00017752130.026
nervous system developmentGO:00073992930.025
regulation of cell migrationGO:00303342890.025
negative regulation of cellular component organizationGO:00511292350.025
rho protein signal transductionGO:0007266260.025
regulation of innate immune responseGO:0045088970.025
neuromuscular junction developmentGO:000752830.025
positive regulation of kinase activityGO:00336742040.024
regulation of multi organism processGO:00439001570.024
positive regulation of mapk cascadeGO:00434101900.024
regulation of cellular component movementGO:00512703340.024
morphogenesis of embryonic epitheliumGO:001633140.024
positive regulation of defense responseGO:0031349870.024
cellular response to dna damage stimulusGO:00069743790.024
negative regulation of protein processingGO:00109551420.023
circadian behaviorGO:004851220.023
single organism cellular localizationGO:19025803320.023
positive regulation of cell differentiationGO:00455972110.023
endomembrane system organizationGO:00102561960.023
nitrogen compound transportGO:00717051910.023
single organism membrane organizationGO:00448022680.023
regulation of secretion by cellGO:19035301770.022
regulation of protein kinase activityGO:00458592890.022
response to abiotic stimulusGO:00096283360.022
multi organism cellular processGO:00447641560.022
positive regulation of gtp catabolic processGO:00331261660.022
chemical homeostasisGO:00488783060.022
response to nitrogen compoundGO:19016981840.022
enzyme linked receptor protein signaling pathwayGO:00071673030.022
rhythmic behaviorGO:000762220.022
regulation of cellular response to stressGO:00801352440.021
motor neuron axon guidanceGO:000804520.021
regulation of protein processingGO:00706131500.021
secretion by cellGO:00329402260.021
positive regulation of innate immune responseGO:0045089790.021
regulation of protein secretionGO:0050708860.021
cellular protein catabolic processGO:00442572610.021
response to virusGO:00096151260.021
dephosphorylationGO:00163112090.021
negative regulation of proteolysisGO:00458611320.021
blastoderm segmentationGO:000735020.020
transmembrane transportGO:00550853990.020
defense response to other organismGO:00985421290.020
cellular component morphogenesisGO:00329893140.020
proteolysis involved in cellular protein catabolic processGO:00516032440.020
mitotic cell cycle processGO:19030472860.020
negative regulation of programmed cell deathGO:00430693210.020
negative regulation of endopeptidase activityGO:0010951840.020
alcohol metabolic processGO:00060661140.020
generation of neuronsGO:00486991520.020
compound eye developmentGO:004874910.020
response to woundingGO:00096111680.020
secretionGO:00469032540.019
cellular macromolecular complex assemblyGO:00346223240.019
syncytium formation by plasma membrane fusionGO:000076820.019
positive regulation of cell deathGO:00109422630.019
protein localization to organelleGO:00333652800.019
activation of innate immune responseGO:0002218550.019
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.019
mitotic cell cycleGO:00002783260.019
positive regulation of secretion by cellGO:19035321080.019
cation transportGO:00068123310.019
regulation of cell motilityGO:20001452990.019
regulation of ras gtpase activityGO:00323181280.019
regulation of protein catabolic processGO:00421761550.019
positive regulation of cell proliferationGO:00082843010.019
interspecies interaction between organismsGO:00444191560.019
regulation of small gtpase mediated signal transductionGO:00510561560.018
ion transmembrane transportGO:00342203380.018
cell cell signalingGO:00072671550.018
matingGO:000761810.018
regulation of protein serine threonine kinase activityGO:00719001790.018
actin filament based movementGO:0030048170.018
spermatid developmentGO:000728640.018
cellular protein complex assemblyGO:00436231880.018
symbiosis encompassing mutualism through parasitismGO:00444031560.018
organophosphate biosynthetic processGO:00904071630.018
epithelium developmentGO:00604292270.018
regulation of cysteine type endopeptidase activityGO:20001161270.018
viral processGO:00160321460.018
organic anion transportGO:00157111030.018
defense response to virusGO:0051607710.018
protein targetingGO:00066051870.018
negative regulation of cell deathGO:00605483450.018
carbohydrate metabolic processGO:00059752070.018
negative regulation of transportGO:00510511760.018
embryonic epithelial tube formationGO:000183840.018
negative regulation of peptidase activityGO:0010466910.018
negative regulation of cellular amine metabolic processGO:003323930.018
organic acid biosynthetic processGO:0016053970.018
cellular response to cytokine stimulusGO:00713451810.018
neuroblast proliferationGO:000740540.018
response to hormoneGO:00097251750.018
cellular response to lipidGO:00713961270.018
oocyte differentiationGO:000999420.018
organic hydroxy compound metabolic processGO:19016151470.017
neuron differentiationGO:00301821380.017
response to organonitrogen compoundGO:00102431560.017
sulfur compound metabolic processGO:00067901010.017
immune response activating signal transductionGO:0002757900.017
single organism cell adhesionGO:00986021790.017
protein secretionGO:0009306980.017
regulation of viral processGO:00507921030.017
cellular response to growth factor stimulusGO:00713631970.017
cellular response to external stimulusGO:00714961110.017
positive regulation of programmed cell deathGO:00430682490.017
anion transportGO:00068201610.017
regulation of leukocyte activationGO:00026941150.017
ion homeostasisGO:00508012300.017
immune response regulating signaling pathwayGO:0002764970.017
maintenance of locationGO:00512351120.017
reactive oxygen species metabolic processGO:0072593750.017
tissue regenerationGO:004224630.017
chromatin modificationGO:00165682980.017
single organismal cell cell adhesionGO:00163371480.017
regulation of ras protein signal transductionGO:00465781550.016
negative regulation of apoptotic processGO:00430663160.016
neuron projection regenerationGO:003110210.016
neuron projection developmentGO:00311751060.016
cation transmembrane transportGO:00986552380.016
nuclear transportGO:00511691790.016
endocytosisGO:00068971590.016
cell part morphogenesisGO:00329901370.016
carboxylic acid biosynthetic processGO:0046394970.016
immune system developmentGO:00025201950.016
somatic stem cell divisionGO:004810310.016
response to growth factorGO:00708482050.016
i kappab kinase nf kappab signalingGO:00072491660.016
steroid metabolic processGO:0008202940.016
organ formationGO:004864530.016
regulation of intracellular transportGO:00323861950.016
regulation of cell adhesionGO:00301551660.016
response to lipidGO:00339932060.016
sleepGO:003043120.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
cellular response to abiotic stimulusGO:00712141170.016
positive regulation of proteolysisGO:00458621420.016
ribonucleoside monophosphate metabolic processGO:00091611870.016
positive regulation of secretionGO:00510471160.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
regulation of cytoplasmic transportGO:19036491490.016
glycoprotein biosynthetic processGO:0009101910.016
viral life cycleGO:00190581320.016
spermatid differentiationGO:004851540.016
monocarboxylic acid metabolic processGO:00327871850.016
myoblast fusionGO:000752010.016
intracellular protein transportGO:00068862700.016
positive regulation of cellular component biogenesisGO:00440891580.016
cell projection morphogenesisGO:00488581290.016
cell cycle phase transitionGO:00447701730.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
cytokine mediated signaling pathwayGO:00192211090.016
reactive oxygen species biosynthetic processGO:190340940.016
neurogenesisGO:00220081690.016
nucleocytoplasmic transportGO:00069131760.015
cytokine secretionGO:0050663640.015
negative regulation of phosphorylationGO:00423261740.015
inorganic cation transmembrane transportGO:00986621940.015
negative regulation of intracellular signal transductionGO:19025321830.015
metal ion transportGO:00300012720.015
release of cytoplasmic sequestered nf kappabGO:000858840.015
positive regulation of nf kappab transcription factor activityGO:0051092810.015
positive regulation of cell cycleGO:00457871400.015
reactive nitrogen species metabolic processGO:200105730.015
negative regulation of cell cycleGO:00457861930.015
actin mediated cell contractionGO:0070252120.015
oocyte developmentGO:004859910.015
regulation of meiotic cell cycleGO:005144540.015
wnt signaling pathwayGO:00160551560.015
cation homeostasisGO:00550801890.015
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.015
neuron developmentGO:00486661130.015
positive regulation of cysteine type endopeptidase activityGO:2001056790.015
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.015
protein oligomerizationGO:00512591730.015
primary neural tube formationGO:001402030.015
cell growthGO:00160491600.015
peripheral nervous system developmentGO:000742220.015
tube closureGO:006060630.015
negative regulation of protein modification processGO:00314002000.015
anterior posterior axis specificationGO:000994820.015
specification of organ identityGO:001009230.015
neural tube formationGO:000184130.015
regulation of apoptotic signaling pathwayGO:20012331750.015
endosomal transportGO:00161971290.015
cellular homeostasisGO:00197251960.015
cellular component disassemblyGO:0022411920.015
cellular amide metabolic processGO:0043603690.015
positive regulation of ras gtpase activityGO:00323201170.014
modification dependent protein catabolic processGO:00199412090.014
lipid localizationGO:00108761060.014
nerve developmentGO:002167540.014
regulation of reactive oxygen species metabolic processGO:2000377410.014
adult locomotory behaviorGO:000834410.014
posttranscriptional regulation of gene expressionGO:00106082130.014
lymphocyte activationGO:00466491330.014
angiogenesisGO:00015251470.014
epithelial cell differentiationGO:00308551410.014
regulation of cell developmentGO:00602841610.014
regulation of intracellular protein transportGO:00331571230.014
cellular chemical homeostasisGO:00550821800.014
establishment of protein localization to organelleGO:00725941720.014
response to bacteriumGO:00096171440.014
circulatory system developmentGO:00723592620.014
tripartite regional subdivisionGO:000735120.014
positive regulation of peptidase activityGO:0010952880.014
neurotransmitter secretionGO:000726940.014
regulation of cell cycle phase transitionGO:19019871260.014
plasma membrane organizationGO:00070091150.014
regulation of ion transportGO:00432691890.014
regulation of mitotic cell cycleGO:00073461890.014
purine nucleoside monophosphate catabolic processGO:00091281580.014
somitogenesisGO:000175620.014
negative regulation of developmental processGO:00510932470.014
myeloid cell differentiationGO:00300991170.014
negative regulation of protein phosphorylationGO:00019331400.014
purine ribonucleoside monophosphate catabolic processGO:00091691580.014
protein autophosphorylationGO:00467771230.014
mitotic cell cycle phase transitionGO:00447721620.014
response to organic cyclic compoundGO:00140702040.014
response to axon injuryGO:004867810.014
regulation of anatomical structure morphogenesisGO:00226032860.014
regulation of synaptic plasticityGO:004816730.014
negative regulation of immune system processGO:00026831360.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
regulation of neural precursor cell proliferationGO:200017740.013
purine containing compound biosynthetic processGO:0072522880.013
peptidyl tyrosine modificationGO:00182121700.013
response to fungusGO:000962040.013
cell morphogenesis involved in differentiationGO:00009041440.013
nucleoside monophosphate metabolic processGO:00091231910.013
hemopoiesisGO:00300971800.013
activation of protein kinase activityGO:0032147900.013
cell divisionGO:00513011680.013
protein ubiquitinationGO:00165673140.013
proteasomal protein catabolic processGO:00104981760.013
osteoblast differentiationGO:0001649920.013
morphogenesis of a polarized epitheliumGO:000173830.013
response to radiationGO:00093141510.013
response to molecule of bacterial originGO:0002237820.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.013
modification dependent macromolecule catabolic processGO:00436322120.013
regulation of bindingGO:00510981110.013
regulation of protein complex assemblyGO:00432541470.013
regulation of wnt signaling pathwayGO:00301111230.013
cardiac muscle cell contractionGO:008600340.013
covalent chromatin modificationGO:00165692540.013
regulation of lymphocyte activationGO:00512491030.013
extrinsic apoptotic signaling pathwayGO:00971911190.013
blood vessel developmentGO:00015681720.013
response to tumor necrosis factorGO:0034612760.013
sequestering of metal ionGO:0051238240.013
hindbrain developmentGO:003090230.013
reproductive processGO:00224141060.013
neural tube closureGO:000184330.013
glycoprotein metabolic processGO:00091001100.013
positive regulation of locomotionGO:00400171860.013
regulation of protein targetingGO:1903533910.013
actin cytoskeleton organizationGO:00300362070.013
cellular response to glucocorticoid stimulusGO:007138540.013
negative regulation of cysteine type endopeptidase activityGO:2000117480.013
ubiquitin dependent protein catabolic processGO:00065112060.013
developmental programmed cell deathGO:001062330.013
negative regulation of multicellular organismal processGO:00512413170.013
muscle system processGO:0003012810.013
nucleoside monophosphate catabolic processGO:00091251590.013
negative regulation of cell proliferationGO:00082852280.013
limbic system developmentGO:002176130.012
chromatin organizationGO:00063253510.012
melanin metabolic processGO:000658210.012
positive regulation of intracellular transportGO:00323881040.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
positive regulation of cell motilityGO:20001471770.012
histone modificationGO:00165702510.012
anterior posterior axis specification embryoGO:000859520.012
negative regulation of transferase activityGO:00513481240.012
protein localization to membraneGO:00726571600.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
blood vessel morphogenesisGO:00485141620.012
zymogen activationGO:0031638700.012
regulation of cellular protein catabolic processGO:1903362960.012
vesicle organizationGO:0016050620.012
positive regulation of organelle organizationGO:00106381950.012
intrinsic apoptotic signaling pathwayGO:00971931270.012
cell fate determinationGO:000170930.012
ribonucleoside monophosphate catabolic processGO:00091581580.012
microtubule based processGO:00070172100.012
regulation of growthGO:00400081650.012
regulation of vesicle mediated transportGO:00606271300.012
protein modification by small protein conjugationGO:00324463420.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
autophagyGO:0006914880.012
positive regulation of transferase activityGO:00513472270.012
inorganic ion transmembrane transportGO:00986602310.012
atp catabolic processGO:00062001570.012
atp metabolic processGO:00460341760.012
single organism carbohydrate metabolic processGO:00447231930.012
sulfur compound biosynthetic processGO:0044272380.012
alditol phosphate metabolic processGO:005264630.012
establishment of planar polarityGO:000173630.012
stem cell divisionGO:001714520.012
central nervous system developmentGO:00074171230.012
regulation of cytokine secretionGO:0050707570.012
positive regulation of protein serine threonine kinase activityGO:00719021190.012
protein importGO:00170381300.012
membrane hyperpolarizationGO:006008110.012
negative regulation of catabolic processGO:00098951040.012
growthGO:00400072020.012
regulation of cell projection organizationGO:00313441070.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
divalent inorganic cation transportGO:00725111580.012
regulation of mitotic cell cycle phase transitionGO:19019901180.012
fatty acid metabolic processGO:00066311150.011
positive regulation of synaptic transmissionGO:005080640.011
peptidyl tyrosine phosphorylationGO:00181081700.011
cellular response to lipopolysaccharideGO:0071222570.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
neurological system processGO:00508771630.011
cellular ion homeostasisGO:00068731680.011
chemotaxisGO:00069351570.011
associative learningGO:000830610.011
neural crest cell developmentGO:001403230.011
regulation of response to woundingGO:19030341010.011
protein localization to nucleusGO:00345041360.011
rna processingGO:00063962550.011
rna interferenceGO:001624640.011
cellular response to nutrient levelsGO:0031669690.011
ameboidal type cell migrationGO:00016671350.011
peptidyl serine modificationGO:00182091060.011
activation of cysteine type endopeptidase activityGO:0097202570.011
circadian sleep wake cycleGO:004274520.011
regulation of nucleocytoplasmic transportGO:0046822980.011
synaptic transmission cholinergicGO:000727120.011
divalent metal ion transportGO:00708381520.011
metencephalon developmentGO:002203720.011

DPYD disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.037
nervous system diseaseDOID:8634310.037
eye and adnexa diseaseDOID:14921500.032
eye diseaseDOID:56141490.032
disease of metabolismDOID:00146672950.032
retinal diseaseDOID:56791180.025
cancerDOID:1621670.022
disease of cellular proliferationDOID:145661740.022
immune system diseaseDOID:29141550.019
retinal degenerationDOID:8466890.019
musculoskeletal system diseaseDOID:172230.018
central nervous system diseaseDOID:3311860.017
hematopoietic system diseaseDOID:741000.016
organ system cancerDOID:00506861640.015
inherited metabolic disorderDOID:6552420.014
disease of mental healthDOID:150700.013
neurodegenerative diseaseDOID:12891020.012
muscular diseaseDOID:00800001140.012
muscle tissue diseaseDOID:661130.012
acquired metabolic diseaseDOID:0060158580.011