Homo sapiens

77 known processes

HLA-DMB

major histocompatibility complex, class II, DM beta

(Aliases: D6S221E,RING7)

HLA-DMB biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dendritic cell antigen processing and presentationGO:000246811.000
peptide antigen assembly with mhc protein complexGO:000250141.000
negative regulation of antigen processing and presentationGO:000257850.996
antigen processing and presentation of peptide antigen via mhc class iiGO:0002495110.992
mhc class ii protein complex assemblyGO:000239940.988
antigen processing and presentation of exogenous peptide antigen via mhc class iiGO:001988640.982
polysaccharide assembly with mhc class ii protein complexGO:000250620.971
antigen processing and presentation of peptide or polysaccharide antigen via mhc class iiGO:0002504120.968
de novo protein foldingGO:000645820.961
antigen processing and presentationGO:0019882330.961
antigen processing and presentation of peptide antigenGO:0048002180.958
regulation of interleukin 10 secretionGO:200117940.951
negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class iiGO:000258130.946
positive regulation of myeloid leukocyte cytokine production involved in immune responseGO:006108110.940
peptide antigen assembly with mhc class ii protein complexGO:000250340.934
mhc protein complex assemblyGO:000239640.919
interleukin 10 productionGO:0032613170.914
antigen processing and presentation of exogenous peptide antigenGO:000247840.896
regulation of t cell proliferationGO:0042129420.893
cytokine productionGO:00018162470.838
regulation of antigen processing and presentation of peptide antigen via mhc class iiGO:000258630.834
lymphocyte proliferationGO:0046651700.829
regulation of lymphocyte proliferationGO:0050670640.823
positive thymic t cell selectionGO:004505910.822
protein carbohydrate complex subunit organizationGO:007182320.821
protein carbohydrate complex assemblyGO:006500620.793
positive regulation of lymphocyte proliferationGO:0050671460.784
positive regulation of leukocyte activationGO:0002696800.774
cell activationGO:00017752130.765
peptide secretionGO:0002790510.755
positive regulation of immune responseGO:00507781590.721
regulation of immune responseGO:00507762010.708
t helper 1 type immune responseGO:004208880.707
positive regulation of t cell activationGO:0050870540.700
immune responseGO:00069553070.690
t cell selectionGO:004505840.687
lymphocyte mediated immunityGO:0002449480.685
t cell activationGO:0042110990.683
regulation of leukocyte activationGO:00026941150.678
chaperone mediated protein foldingGO:0061077130.654
negative regulation of antigen processing and presentation of peptide antigenGO:000258430.649
lymphocyte activationGO:00466491330.637
regulation of t cell activationGO:0050863770.635
inflammatory response to antigenic stimulusGO:000243740.635
humoral immune responseGO:0006959490.620
cellular protein complex assemblyGO:00436231880.615
positive regulation of immune system processGO:00026842830.609
adaptive immune responseGO:0002250490.578
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.574
response to bacteriumGO:00096171440.554
regulation of leukocyte proliferationGO:0070663670.554
peptide transportGO:0015833740.546
regulation of cell activationGO:00508651250.545
regulation of cytokine productionGO:00018172320.522
regulation of interferon gamma productionGO:0032649360.521
de novo posttranslational protein foldingGO:005108420.484
leukocyte mediated immunityGO:0002443590.460
leukocyte activationGO:00453211640.455
hematopoietic or lymphoid organ developmentGO:00485341860.449
positive regulation of cell activationGO:0050867810.442
antigen processing and presentation of polysaccharide antigen via mhc class iiGO:000250520.441
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822290.438
immunoglobulin mediated immune responseGO:0016064100.432
positive regulation of insulin secretion involved in cellular response to glucose stimulusGO:003577430.414
cellular macromolecular complex assemblyGO:00346223240.413
positive regulation of antigen processing and presentationGO:000257910.406
positive regulation of t cell proliferationGO:0042102330.399
regulation of defense responseGO:00313471540.395
negative regulation of antigen processing and presentation of peptide antigen via mhc class iiGO:000258720.383
negative regulation of immune system processGO:00026831360.382
positive regulation of lymphocyte activationGO:0051251730.375
positive regulation of lymphocyte differentiationGO:0045621130.374
regulation of interleukin 4 productionGO:003267370.364
negative regulation of cell proliferationGO:00082852280.349
regulation of lymphocyte activationGO:00512491030.342
defense responseGO:00069523150.336
cellular homeostasisGO:00197251960.331
monocarboxylic acid biosynthetic processGO:0072330670.324
response to oxygen containing compoundGO:19017003690.319
innate immune responseGO:00450871780.315
positive regulation of hormone secretionGO:0046887250.312
detection of biotic stimulusGO:0009595210.289
cellular response to interferon gammaGO:0071346240.279
cytokine secretionGO:0050663640.279
detection of external biotic stimulusGO:0098581190.276
secretionGO:00469032540.275
nitrogen compound transportGO:00717051910.272
positive regulation of insulin secretionGO:0032024100.271
hormone secretionGO:0046879650.269
immune system developmentGO:00025201950.264
negative regulation of t cell activationGO:0050868180.263
mononuclear cell proliferationGO:0032943710.242
hemopoiesisGO:00300971800.236
protein foldingGO:0006457380.235
positive regulation of t cell differentiationGO:0045582110.230
cellular response to ammonium ionGO:007124240.226
antigen processing and presentation of exogenous antigenGO:001988440.225
regulation of protein transportGO:00512232130.223
regulation of cell migrationGO:00303342890.223
regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class iiGO:000258040.219
positive regulation of cell motilityGO:20001471770.219
regulation of response to external stimulusGO:00321012220.216
amide transportGO:0042886760.211
response to hexoseGO:0009746200.210
regulation of protein secretionGO:0050708860.209
positive regulation of peptide secretionGO:0002793150.208
regulation of antigen processing and presentation of peptide antigenGO:000258340.203
regulation of response to woundingGO:19030341010.199
b cell mediated immunityGO:0019724100.197
regulation of t cell differentiationGO:0045580190.195
humoral immune response mediated by circulating immunoglobulinGO:000245550.192
positive regulation of peptide hormone secretionGO:0090277150.187
negative regulation of defense responseGO:0031348470.185
positive regulation of cell migrationGO:00303351720.182
regulation of adaptive immune responseGO:0002819330.166
positive regulation of adaptive immune responseGO:0002821210.163
system processGO:00030083490.162
positive regulation of transportGO:00510503360.152
neurological system processGO:00508771630.150
cellular amine metabolic processGO:0044106410.150
regulation of hormone levelsGO:00108171250.149
regulation of peptide hormone secretionGO:0090276410.143
protein oligomerizationGO:00512591730.143
negative regulation of b cell apoptotic processGO:000290340.141
regulation of leukocyte differentiationGO:1902105610.140
positive regulation of developmental processGO:00510943140.139
protein secretionGO:0009306980.138
negative regulation of immune responseGO:0050777400.136
negative regulation of response to external stimulusGO:0032102830.130
regulation of anatomical structure morphogenesisGO:00226032860.124
positive regulation of secretionGO:00510471160.123
leukocyte proliferationGO:0070661740.122
negative regulation of response to woundingGO:1903035470.120
peptide hormone secretionGO:0030072500.118
negative regulation of t cell proliferationGO:004213080.112
inflammatory responseGO:0006954790.109
b cell homeostasisGO:000178210.109
cellular response to oxygen containing compoundGO:19017012760.108
cellular chemical homeostasisGO:00550821800.105
cellular glucose homeostasisGO:0001678110.104
response to cytokineGO:00340972320.102
regulation of mononuclear cell proliferationGO:0032944650.096
negative regulation of cell activationGO:0050866330.096
glucose homeostasisGO:0042593310.095
positive t cell selectionGO:004336820.095
positive regulation of response to external stimulusGO:0032103880.095
hormone transportGO:0009914680.095
azole transportGO:004511740.094
interleukin 10 secretionGO:007260850.084
regulation of protein stabilityGO:0031647870.082
chaperone mediated protein folding requiring cofactorGO:005108510.082
detection of other organismGO:0098543130.081
positive regulation of cellular amine metabolic processGO:003324070.080
regulation of humoral immune responseGO:0002920110.078
positive regulation of mononuclear cell proliferationGO:0032946470.078
regulation of interleukin 10 productionGO:0032653160.078
secretion by cellGO:00329402260.076
regulation of secretionGO:00510461940.073
chemical homeostasisGO:00488783060.072
regulation of cell differentiationGO:00455953930.072
positive regulation of humoral immune responseGO:000292230.071
response to woundingGO:00096111680.071
negative regulation of multicellular organismal processGO:00512413170.068
negative regulation of lymphocyte activationGO:0051250240.068
t cell proliferationGO:0042098450.068
chemokine c x c motif ligand 2 productionGO:007256730.067
positive regulation of protein kinase activityGO:00458601900.066
leukocyte differentiationGO:0002521980.066
regulation of protein localizationGO:00328802960.063
regulation of hormone secretionGO:0046883570.062
interleukin 4 productionGO:003263370.061
prostaglandin biosynthetic processGO:0001516110.061
cellular response to cytokine stimulusGO:00713451810.061
amine metabolic processGO:0009308440.060
fibroblast proliferationGO:0048144330.059
taxisGO:00423301570.058
protein maturationGO:00516042330.058
interferon gamma productionGO:0032609390.057
signal releaseGO:0023061700.056
unsaturated fatty acid metabolic processGO:0033559370.054
negative regulation of hydrolase activityGO:00513461820.053
regulation of insulin secretionGO:0050796330.051
protein tetramerizationGO:0051262470.051
mapk cascadeGO:00001652880.051
cellular response to molecule of bacterial originGO:0071219620.050
negative regulation of catalytic activityGO:00430863350.049
regulation of establishment of protein localizationGO:00702012420.049
regulation of cellular ketone metabolic processGO:0010565500.049
response to fungusGO:000962040.048
cellular response to lipidGO:00713961270.048
regulation of insulin secretion involved in cellular response to glucose stimulusGO:006117870.048
insulin secretion involved in cellular response to glucose stimulusGO:003577370.047
response to external biotic stimulusGO:00432072610.047
cytokine mediated signaling pathwayGO:00192211090.046
regulation of peptide secretionGO:0002791420.045
small gtpase mediated signal transductionGO:0007264780.044
regulation of apoptotic signaling pathwayGO:20012331750.044
negative regulation of cellular component organizationGO:00511292350.044
negative regulation of cell differentiationGO:00455961710.044
endocytosisGO:00068971590.043
t cell differentiationGO:0030217290.043
cellular amino acid metabolic processGO:00065201160.041
immune effector processGO:00022521590.041
fatty acid derivative metabolic processGO:1901568350.041
regulation of antigen processing and presentationGO:000257760.041
regulation of lymphocyte differentiationGO:0045619220.040
response to carbohydrateGO:0009743210.040
positive regulation of cell differentiationGO:00455972110.040
regulation of secretion by cellGO:19035301770.039
posttranscriptional regulation of gene expressionGO:00106082130.039
positive regulation of leukocyte differentiationGO:1902107370.038
negative regulation of leukocyte activationGO:0002695260.038
post embryonic developmentGO:000979120.037
response to molecule of bacterial originGO:0002237820.036
negative regulation of inflammatory responseGO:0050728220.036
regulation of kinase activityGO:00435493140.035
regulation of leukocyte chemotaxisGO:0002688460.035
t cell differentiation in thymusGO:003307740.035
response to other organismGO:00517072610.035
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166640.035
positive regulation of t helper 1 type immune responseGO:000282740.034
multicellular organismal agingGO:001025930.034
immunoglobulin productionGO:0002377120.033
positive regulation of cell deathGO:00109422630.032
intracellular protein transportGO:00068862700.032
ras protein signal transductionGO:0007265730.032
purine nucleotide catabolic processGO:00061954050.031
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824190.031
leukocyte migrationGO:00509001070.031
positive regulation of innate immune responseGO:0045089790.031
negative regulation of neuron projection developmentGO:0010977150.030
regulation of cellular amino acid metabolic processGO:000652160.030
purine ribonucleoside triphosphate metabolic processGO:00092054110.030
positive regulation of secretion by cellGO:19035321080.029
positive regulation of cytokine productionGO:00018191670.029
detection of bacteriumGO:0016045130.029
response to abiotic stimulusGO:00096283360.029
production of molecular mediator of immune responseGO:0002440370.028
purine ribonucleoside catabolic processGO:00461303980.028
lymphocyte differentiationGO:0030098350.027
regulation of locomotionGO:00400123290.027
response to glucoseGO:0009749190.027
fatty acid derivative biosynthetic processGO:1901570180.027
regulation of mapk cascadeGO:00434082620.026
negative regulation of inflammatory response to antigenic stimulusGO:000286220.025
regulation of cellular amine metabolic processGO:0033238110.025
cell projection organizationGO:00300302520.025
response to lipidGO:00339932060.025
purine ribonucleoside triphosphate catabolic processGO:00092073910.025
nucleotide catabolic processGO:00091664080.025
negative regulation of mononuclear cell proliferationGO:0032945150.025
nucleoside triphosphate catabolic processGO:00091433940.024
cellular lipid metabolic processGO:00442553030.024
sensory organ developmentGO:0007423520.024
positive regulation of kinase activityGO:00336742040.024
regulation of chemokine c x c motif ligand 2 productionGO:200034120.024
regulation of cellular response to stressGO:00801352440.024
negative regulation of apoptotic processGO:00430663160.024
regulation of peptide transportGO:0090087620.024
positive regulation of locomotionGO:00400171860.024
cellular cation homeostasisGO:00300031630.023
regulation of nucleotide metabolic processGO:00061402690.023
cellular response to thyroid hormone stimulusGO:009706790.023
negative regulation of cell deathGO:00605483450.023
purine containing compound catabolic processGO:00725234110.023
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555440.022
regulation of purine nucleotide catabolic processGO:00331212050.022
response to nitrogen compoundGO:19016981840.022
cellular ketone metabolic processGO:0042180800.022
oogenesisGO:004847720.022
negative regulation of programmed cell deathGO:00430693210.022
response to biotic stimulusGO:00096072760.022
positive regulation of nucleotide catabolic processGO:00308131850.022
cellular response to carbohydrate stimulusGO:0071322110.022
negative regulation of cytokine productionGO:0001818820.021
rho protein signal transductionGO:0007266260.021
small molecule biosynthetic processGO:00442831570.021
cellular response to glucose stimulusGO:0071333100.020
determination of adult lifespanGO:000834020.020
response to corticosteroidGO:0031960150.020
regulation of chemotaxisGO:0050920740.020
regulation of neutrophil migrationGO:1902622100.020
inositol lipid mediated signalingGO:0048017550.020
negative regulation of peptidase activityGO:0010466910.020
guanosine containing compound catabolic processGO:19010692390.020
nucleoside phosphate catabolic processGO:19012924120.020
regulation of lipopolysaccharide mediated signaling pathwayGO:0031664130.020
regulation of cell developmentGO:00602841610.020
positive regulation of leukocyte proliferationGO:0070665480.019
ribonucleoside triphosphate catabolic processGO:00092033910.019
negative regulation of phosphorus metabolic processGO:00105632670.019
cellular response to dna damage stimulusGO:00069743790.019
negative regulation of apoptotic signaling pathwayGO:2001234970.019
positive regulation of programmed cell deathGO:00430682490.019
purine ribonucleotide catabolic processGO:00091544040.019
regulation of cell cycleGO:00517263930.018
cellular response to monosaccharide stimulusGO:0071326100.018
regulation of chemokine productionGO:0032642310.018
reactive nitrogen species metabolic processGO:200105730.018
regulation of nucleoside metabolic processGO:00091182090.018
response to organic cyclic compoundGO:00140702040.017
carbohydrate metabolic processGO:00059752070.017
organophosphate catabolic processGO:00464344300.017
cell developmentGO:00484683280.017
negative regulation of protein metabolic processGO:00512483910.017
purine nucleoside catabolic processGO:00061523980.017
generation of neuronsGO:00486991520.017
negative regulation of cell cycleGO:00457861930.017
regulation of cell motilityGO:20001452990.017
regulation of purine nucleotide metabolic processGO:19005422640.017
purine ribonucleoside metabolic processGO:00461284370.016
regulation of stress activated protein kinase signaling cascadeGO:0070302850.016
cellular response to nitrogen compoundGO:19016991440.016
nerve developmentGO:002167540.016
response to hormoneGO:00097251750.016
regulation of cellular component movementGO:00512703340.016
ribonucleoside catabolic processGO:00424544060.016
glycosyl compound catabolic processGO:19016584130.016
regulation of gtpase activityGO:00430871800.016
regulation of ras protein signal transductionGO:00465781550.016
negative regulation of phosphorylationGO:00423261740.016
signal transduction by phosphorylationGO:00230142970.016
regulation of nucleotide catabolic processGO:00308112050.016
negative regulation of blood vessel morphogenesisGO:2000181410.016
negative regulation of phosphate metabolic processGO:00459362670.015
actin filament based processGO:00300292240.015
ribonucleotide catabolic processGO:00092614050.015
gtp metabolic processGO:00460392390.015
positive regulation of cellular component movementGO:00512721810.015
positive regulation of phosphorylationGO:00423273940.015
positive regulation of mapk cascadeGO:00434101900.015
mitotic cell cycleGO:00002783260.015
cellular response to endogenous stimulusGO:00714953360.015
regulation of proteolysisGO:00301622930.015
cell cycle arrestGO:0007050710.015
negative regulation of insulin secretion involved in cellular response to glucose stimulusGO:006117910.015
negative regulation of intracellular signal transductionGO:19025321830.015
regulation of t helper 1 type immune responseGO:000282550.015
mitotic cell cycle phase transitionGO:00447721620.014
regulation of cytokine secretionGO:0050707570.014
negative regulation of cellular protein metabolic processGO:00322693530.014
neuron developmentGO:00486661130.014
lipid metabolic processGO:00066293810.014
regulation of vesicle mediated transportGO:00606271300.014
cell morphogenesisGO:00009022960.014
positive regulation of tumor necrosis factor superfamily cytokine productionGO:1903557220.014
activation of immune responseGO:00022531140.014
positive regulation of muscle adaptationGO:001474410.014
detection of stimulusGO:0051606850.014
nucleoside catabolic processGO:00091644080.014
negative regulation of transportGO:00510511760.014
positive regulation of cellular component organizationGO:00511303760.014
protein catabolic processGO:00301633250.014
positive regulation of gtpase activityGO:00435471660.014
negative regulation of interferon gamma productionGO:003268990.014
regulation of protein maturationGO:19033171500.014
female gamete generationGO:000729220.014
regulation of cellular component biogenesisGO:00440872810.014
regulation of interleukin 8 productionGO:0032677490.014
cell cell signalingGO:00072671550.014
negative regulation of cellular catabolic processGO:0031330830.014
cognitionGO:0050890430.014
proteolysis involved in cellular protein catabolic processGO:00516032440.013
positive regulation of catabolic processGO:00098963100.013
single organism carbohydrate metabolic processGO:00447231930.013
guanosine containing compound metabolic processGO:19010682440.013
vesicle mediated transportGO:00161923710.013
response to monosaccharideGO:0034284200.013
regulation of protein serine threonine kinase activityGO:00719001790.013
mitotic cell cycle processGO:19030472860.013
positive regulation of nucleotide metabolic processGO:00459812300.013
regulation of transferase activityGO:00513383550.013
negative regulation of cell developmentGO:0010721480.013
positive regulation of protein phosphorylationGO:00019343130.013
reactive oxygen species metabolic processGO:0072593750.013
positive regulation of nucleoside metabolic processGO:00459791860.013
myeloid dendritic cell activationGO:000177340.013
cellular response to oxidative stressGO:0034599850.012
regulation of protein kinase activityGO:00458592890.012
regulation of rho protein signal transductionGO:0035023790.012
positive regulation of cell proliferationGO:00082843010.012
positive regulation of leukocyte chemotaxisGO:0002690380.012
growthGO:00400072020.012
gtp catabolic processGO:00061842370.012
carbohydrate homeostasisGO:0033500310.012
regulation of inflammatory response to antigenic stimulusGO:000286120.012
nervous system developmentGO:00073992930.012
biological adhesionGO:00226103310.012
purine nucleoside triphosphate catabolic processGO:00091463920.012
cell cycle phase transitionGO:00447701730.012
regulation of mitotic cell cycle phase transitionGO:19019901180.012
regulation of homeostatic processGO:00328441210.012
protein modification by small protein conjugationGO:00324463420.011
positive regulation of hydrolase activityGO:00513453310.011
wound healingGO:00420601150.011
response to dexamethasoneGO:007154810.011
protein ubiquitinationGO:00165673140.011
ameboidal type cell migrationGO:00016671350.011
organic acid biosynthetic processGO:0016053970.011
regulation of syncytium formation by plasma membrane fusionGO:006014220.011
cellular response to organonitrogen compoundGO:00714171240.011
cellular protein catabolic processGO:00442572610.011
protein localization to membraneGO:00726571600.011
memoryGO:000761330.011
lipid catabolic processGO:0016042840.011
tumor necrosis factor superfamily cytokine productionGO:0071706450.011
purine nucleoside triphosphate metabolic processGO:00091444120.011
response to organonitrogen compoundGO:00102431560.011
positive regulation of protein serine threonine kinase activityGO:00719021190.011
regulation of multi organism processGO:00439001570.011
response to alcoholGO:0097305640.011
regulation of cell cycle phase transitionGO:19019871260.010
modification dependent protein catabolic processGO:00199412090.010
reactive oxygen species biosynthetic processGO:190340940.010
protein processingGO:00164852260.010
positive regulation of purine nucleotide metabolic processGO:19005442270.010
nucleoside triphosphate metabolic processGO:00091414220.010
oocyte developmentGO:004859910.010
regulation of i kappab kinase nf kappab signalingGO:00431221620.010
regulation of map kinase activityGO:00434051080.010
interleukin 8 productionGO:0032637510.010
regulation of cell cycle processGO:00105642660.010
cellular lipid catabolic processGO:0044242650.010
ribonucleoside triphosphate metabolic processGO:00091994120.010
monocarboxylic acid metabolic processGO:00327871850.010
regulation of cell adhesionGO:00301551660.010
regulation of ras gtpase activityGO:00323181280.010

HLA-DMB disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.969
connective tissue diseaseDOID:651090.964
musculoskeletal system diseaseDOID:172230.964
hypersensitivity reaction diseaseDOID:0060056250.463
central nervous system diseaseDOID:3311860.327
nervous system diseaseDOID:8634310.327
neurodegenerative diseaseDOID:12891020.117
bone diseaseDOID:0080001880.111
hypersensitivity reaction type iv diseaseDOID:291660.058
bone inflammation diseaseDOID:3342100.046
rheumatoid arthritisDOID:714880.046
arthritisDOID:84880.046
inherited metabolic disorderDOID:6552420.037
disease of metabolismDOID:00146672950.037
brain diseaseDOID:936730.022
primary immunodeficiency diseaseDOID:612360.014
disease of cellular proliferationDOID:145661740.012
organ system cancerDOID:00506861640.011
cancerDOID:1621670.011