Homo sapiens

0 known processes

KLK1

kallikrein 1

(Aliases: KLKR,hK1,Klk6)

KLK1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
actin filament based processGO:00300292240.081
post embryonic developmentGO:000979120.079
seminal clot liquefactionGO:007068410.079
Human
epidermis morphogenesisGO:004873030.077
Human
regulation of cellular component movementGO:00512703340.071
metal ion transportGO:00300012720.071
epithelium developmentGO:00604292270.069
Human
inorganic ion transmembrane transportGO:00986602310.065
protein maturationGO:00516042330.056
Human Mouse
mapk cascadeGO:00001652880.053
response to other organismGO:00517072610.052
immune responseGO:00069553070.052
ion transmembrane transportGO:00342203380.050
ribonucleoside catabolic processGO:00424544060.050
biological adhesionGO:00226103310.048
cell adhesionGO:00071553250.048
organophosphate catabolic processGO:00464344300.047
negative regulation of phosphate metabolic processGO:00459362670.047
lipid metabolic processGO:00066293810.046
Mouse
glycosyl compound catabolic processGO:19016584130.045
system processGO:00030083490.045
Mouse Rat
positive regulation of cellular component organizationGO:00511303760.045
positive regulation of catabolic processGO:00098963100.044
purine nucleotide catabolic processGO:00061954050.043
cation transmembrane transportGO:00986552380.043
small gtpase mediated signal transductionGO:0007264780.043
Mouse
copulationGO:000762010.043
Human
protein processingGO:00164852260.042
Human Mouse
nucleoside phosphate catabolic processGO:19012924120.042
enzyme linked receptor protein signaling pathwayGO:00071673030.041
ras protein signal transductionGO:0007265730.041
purine nucleoside triphosphate metabolic processGO:00091444120.041
purine ribonucleoside triphosphate catabolic processGO:00092073910.040
regulation of cell motilityGO:20001452990.040
cation transportGO:00068123310.040
regulation of cellular amine metabolic processGO:0033238110.040
epithelial cell migrationGO:00106311190.040
Human
inseminationGO:000732010.039
Human
cellular lipid metabolic processGO:00442553030.039
Mouse
determination of adult lifespanGO:000834020.039
purine ribonucleoside metabolic processGO:00461284370.038
signal transduction by phosphorylationGO:00230142970.037
purine nucleoside triphosphate catabolic processGO:00091463920.037
positive regulation of hydrolase activityGO:00513453310.037
nucleoside triphosphate catabolic processGO:00091433940.037
regulation of purine nucleotide catabolic processGO:00331212050.037
ribonucleotide catabolic processGO:00092614050.037
response to biotic stimulusGO:00096072760.037
cellular ketone metabolic processGO:0042180800.037
multicellular organismal agingGO:001025930.037
negative regulation of catalytic activityGO:00430863350.036
response to external biotic stimulusGO:00432072610.036
purine containing compound catabolic processGO:00725234110.036
defense responseGO:00069523150.036
Mouse
epithelium migrationGO:00901321190.035
Human
ribonucleoside triphosphate metabolic processGO:00091994120.035
matingGO:000761810.035
Human
positive regulation of phosphorylationGO:00423273940.035
Mouse
nucleoside catabolic processGO:00091644080.035
actin cytoskeleton organizationGO:00300362070.034
purine ribonucleoside catabolic processGO:00461303980.033
regulation of cell migrationGO:00303342890.033
rho protein signal transductionGO:0007266260.033
transmembrane transportGO:00550853990.033
regulation of cellular amino acid metabolic processGO:000652160.032
anion transportGO:00068201610.032
negative regulation of phosphorus metabolic processGO:00105632670.032
positive regulation of programmed cell deathGO:00430682490.031
dephosphorylationGO:00163112090.031
purine ribonucleotide catabolic processGO:00091544040.031
oogenesisGO:004847720.031
nucleoside triphosphate metabolic processGO:00091414220.031
positive regulation of cellular catabolic processGO:00313312840.031
purine nucleoside catabolic processGO:00061523980.031
cellular amine metabolic processGO:0044106410.031
regulation of ion transportGO:00432691890.031
chemical homeostasisGO:00488783060.030
regulation of locomotionGO:00400123290.030
regulation of mapk cascadeGO:00434082620.030
cellular amino acid metabolic processGO:00065201160.030
cytoplasmic transportGO:00164823790.030
regulation of cell differentiationGO:00455953930.029
epithelial cell differentiationGO:00308551410.029
cardiac muscle cell contractionGO:008600340.029
positive regulation of transportGO:00510503360.029
inorganic cation transmembrane transportGO:00986621940.029
positive regulation of apoptotic processGO:00430652460.028
regulation of nucleoside metabolic processGO:00091182090.028
ribonucleoside triphosphate catabolic processGO:00092033910.028
positive regulation of immune system processGO:00026842830.028
positive regulation of nucleotide catabolic processGO:00308131850.028
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.027
negative regulation of cellular protein metabolic processGO:00322693530.027
regulation of anatomical structure morphogenesisGO:00226032860.027
regulation of nucleotide metabolic processGO:00061402690.027
female gamete generationGO:000729220.027
regulation of cellular component biogenesisGO:00440872810.027
negative regulation of protein metabolic processGO:00512483910.027
ameboidal type cell migrationGO:00016671350.026
Human
guanosine containing compound metabolic processGO:19010682440.026
negative regulation of hydrolase activityGO:00513461820.026
regulation of cellular ketone metabolic processGO:0010565500.025
segmentationGO:003528240.025
positive regulation of cell deathGO:00109422630.025
endothelial cell migrationGO:0043542860.025
Human
negative regulation of cell deathGO:00605483450.025
purine ribonucleoside triphosphate metabolic processGO:00092054110.025
guanosine containing compound catabolic processGO:19010692390.025
positive regulation of nucleotide metabolic processGO:00459812300.025
amine metabolic processGO:0009308440.025
positive regulation of gtp catabolic processGO:00331261660.025
small molecule biosynthetic processGO:00442831570.024
regulation of protein localizationGO:00328802960.024
cellular macromolecular complex assemblyGO:00346223240.024
nucleotide catabolic processGO:00091664080.024
regulation of cytoskeleton organizationGO:00514931770.024
actin filament based movementGO:0030048170.024
regulation of transferase activityGO:00513383550.024
Mouse
positive regulation of cell proliferationGO:00082843010.024
secretionGO:00469032540.024
regulation of response to external stimulusGO:00321012220.024
regulation of cytokine productionGO:00018172320.024
cytokine productionGO:00018162470.023
regulation of purine nucleotide metabolic processGO:19005422640.023
protein catabolic processGO:00301633250.023
cellular protein complex assemblyGO:00436231880.023
negative regulation of cell proliferationGO:00082852280.023
tissue migrationGO:00901301190.023
Human
positive regulation of mapk cascadeGO:00434101900.023
gtp catabolic processGO:00061842370.023
cellular macromolecule catabolic processGO:00442653800.023
response to growth factorGO:00708482050.023
skin developmentGO:0043588760.022
Human
monovalent inorganic cation transportGO:00156721280.022
mitotic cell cycleGO:00002783260.022
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.022
regulation of protein kinase activityGO:00458592890.022
epidermis developmentGO:0008544590.022
Human
positive regulation of purine nucleotide catabolic processGO:00331231850.022
gtp metabolic processGO:00460392390.022
cellular component morphogenesisGO:00329893140.022
regulation of cell cycleGO:00517263930.022
neuromuscular junction developmentGO:000752830.022
negative regulation of programmed cell deathGO:00430693210.022
actin mediated cell contractionGO:0070252120.022
regulation of actin filament based processGO:00329701410.022
blood circulationGO:00080151130.022
Mouse Rat
single organism cellular localizationGO:19025803320.021
regulation of kinase activityGO:00435493140.021
Mouse
maintenance of locationGO:00512351120.021
regulation of nucleotide catabolic processGO:00308112050.021
membrane organizationGO:00610242920.021
regulation of proteolysisGO:00301622930.021
regulation of gtp catabolic processGO:00331241800.021
actin filament organizationGO:00070151280.021
positive regulation of purine nucleotide metabolic processGO:19005442270.021
positive regulation of transferase activityGO:00513472270.021
Mouse
regulation of cell adhesionGO:00301551660.021
organ morphogenesisGO:00098871470.021
Human Mouse
positive regulation of nucleoside metabolic processGO:00459791860.021
ion homeostasisGO:00508012300.021
regulation of cellular response to stressGO:00801352440.020
peripheral nervous system developmentGO:000742220.020
muscle system processGO:0003012810.020
Mouse
memoryGO:000761330.020
cell projection organizationGO:00300302520.020
positive regulation of cellular amine metabolic processGO:003324070.020
positive regulation of cellular component biogenesisGO:00440891580.020
positive regulation of cellular amino acid metabolic processGO:004576430.020
cell substrate adhesionGO:00315891320.020
positive regulation of immune responseGO:00507781590.020
zymogen activationGO:0031638700.020
Human Mouse
single organism cell adhesionGO:00986021790.020
angiotensin activated signaling pathwayGO:003816640.020
regulation of dephosphorylationGO:0035303960.020
carbohydrate metabolic processGO:00059752070.020
blastoderm segmentationGO:000735020.020
cellular homeostasisGO:00197251960.020
somatic stem cell maintenanceGO:003501940.019
regulation of actin cytoskeleton organizationGO:00329561160.019
cardiovascular system developmentGO:00723582620.019
Mouse
single organism membrane organizationGO:00448022680.019
negative regulation of protein modification processGO:00314002000.019
apoptotic signaling pathwayGO:00971902680.019
anatomical structure formation involved in morphogenesisGO:00486462840.019
positive regulation of gtpase activityGO:00435471660.019
negative regulation of cellular amine metabolic processGO:003323930.018
lipid localizationGO:00108761060.018
cellular response to dna damage stimulusGO:00069743790.018
single organismal cell cell adhesionGO:00163371480.018
endomembrane system organizationGO:00102561960.018
regulation of establishment of protein localizationGO:00702012420.018
cellular chemical homeostasisGO:00550821800.018
regulation of gtpase activityGO:00430871800.018
regulation of immune responseGO:00507762010.018
negative regulation of cellular component organizationGO:00511292350.018
regulation of phosphatase activityGO:0010921810.018
cell growthGO:00160491600.017
negative regulation of phosphorylationGO:00423261740.017
cellular metal ion homeostasisGO:00068751460.017
regulation of transmembrane transportGO:00347621390.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
cell activationGO:00017752130.017
vesicle mediated transportGO:00161923710.017
organic anion transportGO:00157111030.017
positive regulation of ras gtpase activityGO:00323201170.017
wnt signaling pathwayGO:00160551560.017
mitotic cell cycle processGO:19030472860.017
defense response to other organismGO:00985421290.017
cell developmentGO:00484683280.017
regulation of protein transportGO:00512232130.017
drinking behaviorGO:004275610.017
nervous system developmentGO:00073992930.017
cellular protein catabolic processGO:00442572610.016
organelle assemblyGO:00709251760.016
negative regulation of developmental processGO:00510932470.016
positive regulation of kinase activityGO:00336742040.016
Mouse
regulation of body fluid levelsGO:0050878990.016
neurological system processGO:00508771630.016
Mouse
negative regulation of intracellular signal transductionGO:19025321830.016
regulation of ras gtpase activityGO:00323181280.016
regulation of cell developmentGO:00602841610.016
morphogenesis of embryonic epitheliumGO:001633140.016
regulation of protein complex assemblyGO:00432541470.016
regulation of small gtpase mediated signal transductionGO:00510561560.016
t cell activationGO:0042110990.016
spermatid differentiationGO:004851540.016
regulation of i kappab kinase nf kappab signalingGO:00431221620.016
protein localization to organelleGO:00333652800.016
cell morphogenesisGO:00009022960.016
proteolysis involved in cellular protein catabolic processGO:00516032440.015
organonitrogen compound biosynthetic processGO:19015662000.015
Mouse
negative regulation of apoptotic processGO:00430663160.015
posttranscriptional regulation of gene expressionGO:00106082130.015
lipid biosynthetic processGO:00086101770.015
photoreceptor cell differentiationGO:004653020.015
regulation of dna metabolic processGO:00510521530.015
regulation of sequence specific dna binding transcription factor activityGO:00510902110.015
regulation of apoptotic signaling pathwayGO:20012331750.015
oxidation reduction processGO:00551143960.015
establishment of protein localization to membraneGO:00901501210.015
protein ubiquitinationGO:00165673140.015
glycerolipid metabolic processGO:00464861070.015
Mouse
hindbrain developmentGO:003090230.015
i kappab kinase nf kappab signalingGO:00072491660.015
divalent metal ion transportGO:00708381520.015
leukocyte migrationGO:00509001070.015
regulation of cell growthGO:00015581350.015
positive regulation of locomotionGO:00400171860.015
positive regulation of organelle organizationGO:00106381950.015
cardiac muscle contractionGO:0060048340.015
Mouse
positive regulation of cytokine productionGO:00018191670.015
response to abiotic stimulusGO:00096283360.015
intrinsic apoptotic signaling pathwayGO:00971931270.015
regulation of cell cycle processGO:00105642660.015
oocyte developmentGO:004859910.015
action potentialGO:0001508340.014
negative regulation of cell motilityGO:20001461040.014
regulation of peptidase activityGO:00525471800.014
mitochondrion organizationGO:00070051560.014
regulation of cell morphogenesisGO:00226041530.014
secretion by cellGO:00329402260.014
salivary gland morphogenesisGO:000743540.014
immune system developmentGO:00025201950.014
locomotory behaviorGO:000762610.014
positive regulation of cell differentiationGO:00455972110.014
multicellular organismal signalingGO:0035637340.014
regulation of protein serine threonine kinase activityGO:00719001790.014
innate immune responseGO:00450871780.014
regulation of endopeptidase activityGO:00525481700.014
regulation of secretionGO:00510461940.014
covalent chromatin modificationGO:00165692540.014
negative regulation of transferase activityGO:00513481240.014
cell matrix adhesionGO:0007160850.014
cell divisionGO:00513011680.014
protein modification by small protein conjugationGO:00324463420.014
chromatin modificationGO:00165682980.014
stress activated mapk cascadeGO:0051403930.014
response to fungusGO:000962040.014
intracellular protein transportGO:00068862700.014
protein targetingGO:00066051870.014
chromatin organizationGO:00063253510.014
single organism carbohydrate metabolic processGO:00447231930.014
regulation of hormone levelsGO:00108171250.014
growthGO:00400072020.014
regulation of mitotic cell cycleGO:00073461890.014
regulation of cell projection organizationGO:00313441070.013
stress activated protein kinase signaling cascadeGO:0031098940.013
reactive oxygen species biosynthetic processGO:190340940.013
motor neuron axon guidanceGO:000804520.013
spermatid developmentGO:000728640.013
positive regulation of ion transportGO:0043270870.013
visual behaviorGO:000763220.013
regulation of ras protein signal transductionGO:00465781550.013
sodium ion transmembrane transportGO:0035725590.013
nucleoside monophosphate metabolic processGO:00091231910.013
sensory perceptionGO:00076001030.013
regulation of vasculature developmentGO:1901342970.013
response to bacteriumGO:00096171440.013
protein localization to membraneGO:00726571600.013
hemostasisGO:0007599760.013
cellular response to oxygen containing compoundGO:19017012760.013
reactive oxygen species metabolic processGO:0072593750.013
thymus developmentGO:004853830.013
positive regulation of developmental processGO:00510943140.013
cell cycle phase transitionGO:00447701730.013
monocarboxylic acid metabolic processGO:00327871850.013
cell projection assemblyGO:00300311260.013
modification dependent macromolecule catabolic processGO:00436322120.013
negative regulation of cell cycleGO:00457861930.013
epithelial cell proliferationGO:00506731280.013
carboxylic acid transportGO:0046942630.013
rhythmic behaviorGO:000762220.013
associative learningGO:000830610.013
muscle contractionGO:0006936730.013
Mouse
negative regulation of growthGO:0045926970.013
cellular response to abiotic stimulusGO:00712141170.013
calcium ion transportGO:00068161470.013
head developmentGO:00603221080.013
regulation of wnt signaling pathwayGO:00301111230.013
regulation of multi organism processGO:00439001570.013
oocyte differentiationGO:000999420.013
hemopoiesisGO:00300971800.012
nitrogen compound transportGO:00717051910.012
protein autophosphorylationGO:00467771230.012
microtubule based processGO:00070172100.012
immune effector processGO:00022521590.012
positive regulation of intracellular transportGO:00323881040.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
regulation of meiotic cell cycleGO:005144540.012
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
regulation of ion transmembrane transportGO:00347651320.012
negative regulation of cell growthGO:0030308830.012
circulatory system developmentGO:00723592620.012
Mouse
regulation of axon extension involved in axon guidanceGO:004884120.012
negative regulation of locomotionGO:00400131180.012
glycoprotein metabolic processGO:00091001100.012
regenerationGO:003109940.012
t cell differentiation in thymusGO:003307740.012
regulation of axon guidanceGO:190266730.012
nerve developmentGO:002167540.012
negative regulation of multicellular organismal processGO:00512413170.012
regulation of protein processingGO:00706131500.012
positive regulation of protein kinase activityGO:00458601900.012
negative regulation of cellular component movementGO:00512711060.012
immune response regulating signaling pathwayGO:0002764970.012
cation homeostasisGO:00550801890.012
regulation of anatomical structure sizeGO:00900661010.012
Mouse Rat
detection of chemical stimulus involved in sensory perception of smellGO:005091120.012
blastocyst developmentGO:000182430.012
negative regulation of cell differentiationGO:00455961710.012
intracellular receptor signaling pathwayGO:00305221040.012
cellular response to endogenous stimulusGO:00714953360.012
negative regulation of cell migrationGO:00303361020.012
regulation of cell activationGO:00508651250.012
sulfur compound metabolic processGO:00067901010.012
response to inorganic substanceGO:00100351270.012
anatomical structure homeostasisGO:00602491000.012
atp metabolic processGO:00460341760.012
positive regulation of protein phosphorylationGO:00019343130.012
carboxylic acid biosynthetic processGO:0046394970.012
calcium ion homeostasisGO:00550741220.012
cellular cation homeostasisGO:00300031630.012
cell part morphogenesisGO:00329901370.012
protein oligomerizationGO:00512591730.012
coagulationGO:0050817780.012
regulation of cell substrate adhesionGO:0010810680.012
microtubule cytoskeleton organizationGO:00002261760.012
lipid transportGO:0006869900.012
regulation of cytoplasmic transportGO:19036491490.012
positive regulation of protein transportGO:00512221350.012
rna processingGO:00063962550.011
positive regulation of proteolysisGO:00458621420.011
negative regulation of organelle organizationGO:00106391260.011
negative regulation of transportGO:00510511760.011
negative regulation of protein phosphorylationGO:00019331400.011
organic acid transportGO:0015849650.011
viral processGO:00160321460.011
histone modificationGO:00165702510.011
peptide metabolic processGO:0006518510.011
Mouse
regulation of reactive oxygen species biosynthetic processGO:190342630.011
epidermal cell differentiationGO:0009913450.011
response to axon injuryGO:004867810.011
synaptic transmission glycinergicGO:006001210.011
midgut developmentGO:000749410.011
circadian behaviorGO:004851220.011
retina homeostasisGO:0001895420.011
cellular response to metal ionGO:0071248430.011
circulatory system processGO:00030131130.011
Mouse Rat
regulation of stress activated protein kinase signaling cascadeGO:0070302850.011
positive regulation of cellular component movementGO:00512721810.011
response to cytokineGO:00340972320.011
detection of chemical stimulus involved in sensory perceptionGO:0050907330.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
organic hydroxy compound metabolic processGO:19016151470.011
fucosylationGO:003606540.011
regulation of growthGO:00400081650.011
striated muscle contractionGO:0006941520.011
Mouse
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.011
protein secretionGO:0009306980.011
canonical wnt signaling pathwayGO:00600701160.011
regulation of wound healingGO:0061041560.011
tripartite regional subdivisionGO:000735120.011
positive regulation of apoptotic signaling pathwayGO:2001235700.011
activation of immune responseGO:00022531140.011
single organism reproductive processGO:0044702980.011
Human
somitogenesisGO:000175620.011
negative regulation of phosphatase activityGO:0010923610.011
cellular component disassemblyGO:0022411920.011
regulation of leukocyte activationGO:00026941150.011
response to salt stressGO:000965130.011
rab protein signal transductionGO:003248240.011
myosin filament organizationGO:003103320.011
regulation of stress activated mapk cascadeGO:0032872840.011
defense response to fungusGO:005083240.011
sequestering of calcium ionGO:0051208170.011
organic acid biosynthetic processGO:0016053970.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
detection of stimulusGO:0051606850.011
myosin filament assemblyGO:003103420.011
multicellular organismal homeostasisGO:0048871670.011
regulation of defense responseGO:00313471540.011
regulation of cellular component sizeGO:0032535820.011
sleepGO:003043120.011
regulation of intracellular transportGO:00323861950.011
negative regulation of immune system processGO:00026831360.011
cellular ion homeostasisGO:00068731680.011
av node cell to bundle of his cell communicationGO:008606740.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
hair follicle morphogenesisGO:003106920.010
nuclear transportGO:00511691790.010
compound eye developmentGO:004874910.010
negative regulation of kinase activityGO:00336731060.010
cell junction organizationGO:0034330790.010
positive regulation of cell adhesionGO:0045785840.010
tissue morphogenesisGO:0048729960.010
Human Mouse
sensory perception of painGO:001923340.010
response to woundingGO:00096111680.010
establishment of protein localization to organelleGO:00725941720.010
detection of chemical stimulusGO:0009593550.010
regulation of rho protein signal transductionGO:0035023790.010
immune response activating signal transductionGO:0002757900.010
protein polymerizationGO:0051258710.010
regulation of blood circulationGO:1903522590.010
Rat
anterior posterior axis specificationGO:000994820.010
limbic system developmentGO:002176130.010
regulation of cysteine type endopeptidase activityGO:20001161270.010
regulation of immune effector processGO:0002697910.010
endosomal transportGO:00161971290.010
metal ion homeostasisGO:00550651690.010
central nervous system developmentGO:00074171230.010
modification dependent protein catabolic processGO:00199412090.010
wound healingGO:00420601150.010
inner ear morphogenesisGO:004247240.010
g protein coupled receptor signaling pathwayGO:00071862070.010
Human
cellular response to cytokine stimulusGO:00713451810.010
regulation of protein catabolic processGO:00421761550.010
adult locomotory behaviorGO:000834410.010
heart formationGO:006091420.010
melanin metabolic processGO:000658210.010
methylationGO:00322591060.010
purine nucleoside monophosphate metabolic processGO:00091261860.010
positive regulation of cytoskeleton organizationGO:0051495830.010
metencephalon developmentGO:002203720.010
regulation of intracellular protein transportGO:00331571230.010
regulation of homeostatic processGO:00328441210.010

KLK1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.025
nervous system diseaseDOID:8634310.025
neurodegenerative diseaseDOID:12891020.020
central nervous system diseaseDOID:3311860.020
disease of cellular proliferationDOID:145661740.020
organ system cancerDOID:00506861640.018
cancerDOID:1621670.018
musculoskeletal system diseaseDOID:172230.017
disease of metabolismDOID:00146672950.014
immune system diseaseDOID:29141550.013
eye and adnexa diseaseDOID:14921500.013
eye diseaseDOID:56141490.013
retinal diseaseDOID:56791180.012
neuropathyDOID:870520.012
connective tissue diseaseDOID:651090.011
auditory system diseaseDOID:2742530.011
nonsyndromic deafnessDOID:0050563500.010