Homo sapiens

7 known processes

KLK2

kallikrein-related peptidase 2

(Aliases: hK2,KLK2A2,MGC12201)

KLK2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
inseminationGO:000732010.602
Human
seminal clot liquefactionGO:007068410.472
Human
matingGO:000761810.437
Human
epidermis morphogenesisGO:004873030.414
Human
copulationGO:000762010.384
Human
system processGO:00030083490.179
protein processingGO:00164852260.163
Human
ion transmembrane transportGO:00342203380.163
cation transportGO:00068123310.151
transmembrane transportGO:00550853990.144
inorganic ion transmembrane transportGO:00986602310.127
protein maturationGO:00516042330.124
Human
metal ion transportGO:00300012720.122
cation transmembrane transportGO:00986552380.117
epithelium developmentGO:00604292270.113
Human
response to oxygen containing compoundGO:19017003690.100
g protein coupled receptor signaling pathwayGO:00071862070.098
Human
defense responseGO:00069523150.088
zymogen activationGO:0031638700.083
Human
chemical homeostasisGO:00488783060.080
immune responseGO:00069553070.080
organ morphogenesisGO:00098871470.075
Human
blood circulationGO:00080151130.059
inorganic cation transmembrane transportGO:00986621940.058
regulation of ion transportGO:00432691890.056
metal ion homeostasisGO:00550651690.055
regulation of transferase activityGO:00513383550.051
innate immune responseGO:00450871780.050
regulation of hormone levelsGO:00108171250.047
cellular amino acid metabolic processGO:00065201160.047
response to biotic stimulusGO:00096072760.047
morphogenesis of an epitheliumGO:0002009600.046
Human
regulation of cellular amino acid metabolic processGO:000652160.046
positive regulation of transferase activityGO:00513472270.046
cytoplasmic transportGO:00164823790.044
skin developmentGO:0043588760.044
Human
post embryonic developmentGO:000979120.043
secretionGO:00469032540.041
locomotory behaviorGO:000762610.040
amine metabolic processGO:0009308440.040
neurological system processGO:00508771630.039
response to other organismGO:00517072610.039
organic anion transportGO:00157111030.039
cardiac muscle cell contractionGO:008600340.039
cation homeostasisGO:00550801890.038
circulatory system processGO:00030131130.038
cardiac muscle contractionGO:0060048340.037
cellular metal ion homeostasisGO:00068751460.037
negative regulation of apoptotic processGO:00430663160.037
positive regulation of cell proliferationGO:00082843010.036
muscle contractionGO:0006936730.036
sensory perceptionGO:00076001030.036
positive regulation of developmental processGO:00510943140.036
response to cytokineGO:00340972320.036
actin mediated cell contractionGO:0070252120.035
regulation of cell differentiationGO:00455953930.035
epithelium migrationGO:00901321190.035
Human
actin filament based movementGO:0030048170.035
regulation of membrane potentialGO:0042391950.035
tissue morphogenesisGO:0048729960.035
Human
positive regulation of transportGO:00510503360.034
positive regulation of phosphorylationGO:00423273940.034
intracellular protein transportGO:00068862700.034
positive regulation of protein kinase activityGO:00458601900.034
cellular response to oxygen containing compoundGO:19017012760.034
muscle system processGO:0003012810.033
negative regulation of protein metabolic processGO:00512483910.033
negative regulation of cell deathGO:00605483450.032
positive regulation of immune system processGO:00026842830.032
response to external biotic stimulusGO:00432072610.031
negative regulation of programmed cell deathGO:00430693210.031
ion homeostasisGO:00508012300.031
protein catabolic processGO:00301633250.031
chromatin organizationGO:00063253510.031
regulation of cellular ketone metabolic processGO:0010565500.030
negative regulation of g protein coupled receptor protein signaling pathwayGO:0045744180.030
Human
regulation of proteolysisGO:00301622930.030
anion transportGO:00068201610.030
detection of stimulusGO:0051606850.030
single organism cellular localizationGO:19025803320.030
nitrogen compound transportGO:00717051910.030
multicellular organismal agingGO:001025930.029
cellular amine metabolic processGO:0044106410.029
tissue migrationGO:00901301190.029
Human
monocarboxylic acid metabolic processGO:00327871850.029
protein modification by small protein conjugationGO:00324463420.028
striated muscle contractionGO:0006941520.028
neuromuscular junction developmentGO:000752830.028
cellular cation homeostasisGO:00300031630.028
determination of adult lifespanGO:000834020.028
regulation of cellular amine metabolic processGO:0033238110.028
cardiovascular system developmentGO:00723582620.027
positive regulation of g protein coupled receptor protein signaling pathwayGO:004574590.027
Human
adult locomotory behaviorGO:000834410.027
divalent inorganic cation homeostasisGO:00725071360.027
divalent metal ion transportGO:00708381520.027
regulation of growthGO:00400081650.026
vesicle mediated transportGO:00161923710.026
circadian behaviorGO:004851220.026
circulatory system developmentGO:00723592620.026
regulation of protein maturationGO:19033171500.025
calcium ion transportGO:00068161470.025
protein oligomerizationGO:00512591730.025
regulation of secretionGO:00510461940.024
positive regulation of cellular amine metabolic processGO:003324070.024
protein ubiquitinationGO:00165673140.024
cellular macromolecule catabolic processGO:00442653800.024
response to hormoneGO:00097251750.024
positive regulation of kinase activityGO:00336742040.024
actin filament based processGO:00300292240.024
cellular chemical homeostasisGO:00550821800.024
growthGO:00400072020.024
chromatin modificationGO:00165682980.023
regulation of cell cycleGO:00517263930.023
negative regulation of cellular protein metabolic processGO:00322693530.023
biological adhesionGO:00226103310.023
cell activationGO:00017752130.023
negative regulation of cell proliferationGO:00082852280.023
cellular divalent inorganic cation homeostasisGO:00725031280.023
negative regulation of protein maturationGO:19033181420.023
regulation of protein processingGO:00706131500.023
immune effector processGO:00022521590.023
regulation of protein kinase activityGO:00458592890.023
regulation of protein localizationGO:00328802960.022
cellular ion homeostasisGO:00068731680.022
regulation of kinase activityGO:00435493140.022
monovalent inorganic cation transportGO:00156721280.022
response to bacteriumGO:00096171440.022
regulation of transmembrane transportGO:00347621390.022
positive regulation of protein phosphorylationGO:00019343130.022
hair follicle morphogenesisGO:003106920.022
muscle structure developmentGO:0061061980.022
cytokine productionGO:00018162470.022
enzyme linked receptor protein signaling pathwayGO:00071673030.022
positive regulation of cellular amino acid metabolic processGO:004576430.022
regulation of immune responseGO:00507762010.021
positive regulation of cellular component organizationGO:00511303760.021
regulation of cell activationGO:00508651250.021
positive regulation of immune responseGO:00507781590.021
symbiosis encompassing mutualism through parasitismGO:00444031560.021
negative regulation of cellular amine metabolic processGO:003323930.021
female gamete generationGO:000729220.021
apoptotic signaling pathwayGO:00971902680.021
positive regulation of programmed cell deathGO:00430682490.021
renal system processGO:0003014250.021
regulation of cytoplasmic transportGO:19036491490.021
calcium ion homeostasisGO:00550741220.021
regulation of protein transportGO:00512232130.021
positive regulation of hydrolase activityGO:00513453310.021
multicellular organismal homeostasisGO:0048871670.020
action potentialGO:0001508340.020
multi organism cellular processGO:00447641560.020
anatomical structure formation involved in morphogenesisGO:00486462840.020
regulation of endopeptidase activityGO:00525481700.020
regulation of intracellular transportGO:00323861950.020
regulation of locomotionGO:00400123290.020
positive regulation of ion transportGO:0043270870.020
cellular response to cytokine stimulusGO:00713451810.020
response to lipidGO:00339932060.020
cellular protein catabolic processGO:00442572610.020
positive regulation of cytosolic calcium ion concentrationGO:0007204820.020
protein localization to organelleGO:00333652800.020
response to organic cyclic compoundGO:00140702040.020
cellular ketone metabolic processGO:0042180800.019
anatomical structure homeostasisGO:00602491000.019
urate transportGO:001574730.019
maintenance of locationGO:00512351120.019
rhythmic behaviorGO:000762220.019
humoral immune responseGO:0006959490.019
divalent inorganic cation transportGO:00725111580.019
dephosphorylationGO:00163112090.019
regulation of cellular component movementGO:00512703340.019
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.019
regulation of establishment of protein localizationGO:00702012420.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
cell morphogenesisGO:00009022960.019
regulation of cytokine productionGO:00018172320.019
odontogenesisGO:0042476250.019
Human
cellular homeostasisGO:00197251960.019
leukocyte activationGO:00453211640.018
detection of chemical stimulus involved in sensory perceptionGO:0050907330.018
regulation of leukocyte activationGO:00026941150.018
negative regulation of multicellular organismal processGO:00512413170.018
regulation of sequence specific dna binding transcription factor activityGO:00510902110.018
homeostasis of number of cells in a free living populationGO:004887410.018
anterior posterior axis specificationGO:000994820.018
cell developmentGO:00484683280.018
sleepGO:003043120.018
regulation of peptidase activityGO:00525471800.017
protein acylationGO:00435431380.017
mitotic cell cycleGO:00002783260.017
sensory perception of painGO:001923340.017
lipid metabolic processGO:00066293810.017
regulation of cell divisionGO:00513021160.017
response to abiotic stimulusGO:00096283360.017
negative regulation of hydrolase activityGO:00513461820.017
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiationGO:000325730.017
reproductive processGO:00224141060.017
Human
nervous system developmentGO:00073992930.017
organelle assemblyGO:00709251760.017
endothelial cell migrationGO:0043542860.017
Human
tube developmentGO:00352951250.017
negative regulation of transportGO:00510511760.017
response to woundingGO:00096111680.016
hindbrain developmentGO:003090230.016
potassium ion transmembrane transportGO:0071805600.016
negative regulation of proteolysisGO:00458611320.016
regulation of cell migrationGO:00303342890.016
regulation of cardiac muscle contractionGO:0055117330.016
negative regulation of protein processingGO:00109551420.016
oxidation reduction processGO:00551143960.016
sequestering of metal ionGO:0051238240.016
regulation of anatomical structure morphogenesisGO:00226032860.016
lymphocyte activationGO:00466491330.016
inner ear morphogenesisGO:004247240.016
nicotinate transportGO:200114210.016
tissue homeostasisGO:0001894630.016
activation of immune responseGO:00022531140.016
positive regulation of secretionGO:00510471160.016
covalent chromatin modificationGO:00165692540.016
regulation of defense responseGO:00313471540.016
detection of chemical stimulusGO:0009593550.016
cell adhesionGO:00071553250.016
cell cell signalingGO:00072671550.015
negative regulation of protein modification processGO:00314002000.015
positive regulation of cell deathGO:00109422630.015
negative regulation of catalytic activityGO:00430863350.015
secretion by cellGO:00329402260.015
protein targetingGO:00066051870.015
oogenesisGO:004847720.015
epithelial cell migrationGO:00106311190.015
Human
sodium ion transmembrane transportGO:0035725590.015
negative regulation of locomotionGO:00400131180.015
carbohydrate derivative biosynthetic processGO:19011372070.015
cellular response to endogenous stimulusGO:00714953360.015
av node cell to bundle of his cell communicationGO:008606740.015
inflammatory responseGO:0006954790.015
blood vessel developmentGO:00015681720.015
cellular lipid metabolic processGO:00442553030.015
regulation of ion transmembrane transporter activityGO:0032412720.015
epidermis developmentGO:0008544590.015
Human
regulation of epithelial cell proliferationGO:00506781130.015
negative regulation of immune system processGO:00026831360.015
epithelial cell proliferationGO:00506731280.015
anion transmembrane transportGO:0098656760.015
response to fungusGO:000962040.015
cellular protein complex assemblyGO:00436231880.015
fertilizationGO:0009566120.015
Human
single organism membrane organizationGO:00448022680.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
cell projection organizationGO:00300302520.015
interspecies interaction between organismsGO:00444191560.015
positive regulation of reactive oxygen species biosynthetic processGO:190342820.015
cell divisionGO:00513011680.015
cellular component morphogenesisGO:00329893140.015
regulation of homeostatic processGO:00328441210.014
embryonic camera type eye formationGO:006090020.014
adenylate cyclase inhibiting serotonin receptor signaling pathwayGO:000719820.014
retina homeostasisGO:0001895420.014
regulation of cell cycle processGO:00105642660.014
nucleocytoplasmic transportGO:00069131760.014
regulation of ion homeostasisGO:2000021730.014
multicellular organismal signalingGO:0035637340.014
cellular macromolecular complex assemblyGO:00346223240.014
regulation of metal ion transportGO:00109591200.014
protein acetylationGO:00064731160.014
regulation of multi organism processGO:00439001570.014
neuron deathGO:0070997650.014
Human
cellular response to dna damage stimulusGO:00069743790.014
digestive tract developmentGO:0048565750.014
small molecule biosynthetic processGO:00442831570.014
cd8 positive alpha beta t cell activationGO:003603730.014
sodium ion transportGO:0006814610.014
cellular potassium ion transportGO:0071804600.014
regulation of cellular component biogenesisGO:00440872810.014
nuclear transportGO:00511691790.014
regulation of cellular response to stressGO:00801352440.014
spermatid differentiationGO:004851540.014
establishment of protein localization to organelleGO:00725941720.014
regulation of transporter activityGO:0032409820.014
wound healingGO:00420601150.014
sensory perception of chemical stimulusGO:0007606380.014
immune response regulating signaling pathwayGO:0002764970.014
purine containing compound catabolic processGO:00725234110.014
metencephalon developmentGO:002203720.014
positive regulation of apoptotic processGO:00430652460.014
regulation of g protein coupled receptor protein signaling pathwayGO:0008277350.014
Human
endocrine processGO:0050886250.014
purine ribonucleoside triphosphate metabolic processGO:00092054110.014
regulation of cysteine type endopeptidase activityGO:20001161270.014
ameboidal type cell migrationGO:00016671350.014
Human
positive regulation of cytokine productionGO:00018191670.014
regulation of protein catabolic processGO:00421761550.014
positive regulation of cell differentiationGO:00455972110.013
potassium ion transportGO:0006813620.013
regulation of blood pressureGO:0008217300.013
carboxylic acid transportGO:0046942630.013
regulation of t cell activationGO:0050863770.013
regulation of apoptotic signaling pathwayGO:20012331750.013
negative regulation of cellular component organizationGO:00511292350.013
hormone transportGO:0009914680.013
positive regulation of cell cycleGO:00457871400.013
tube morphogenesisGO:0035239950.013
immune response activating signal transductionGO:0002757900.013
intracellular receptor signaling pathwayGO:00305221040.013
proteasomal protein catabolic processGO:00104981760.013
keratinizationGO:003142420.013
protein homooligomerizationGO:00512601000.013
cerebellum developmentGO:002154920.013
prostate gland developmentGO:003085030.013
regulation of protein modification by small protein conjugation or removalGO:19033201070.013
positive regulation of cell divisionGO:0051781590.013
regulation of cell developmentGO:00602841610.013
mitotic cell cycle processGO:19030472860.013
organic acid biosynthetic processGO:0016053970.013
regulation of lymphocyte activationGO:00512491030.013
ras protein signal transductionGO:0007265730.013
vasodilationGO:004231140.013
response to growth factorGO:00708482050.013
negative regulation of growthGO:0045926970.013
modification dependent macromolecule catabolic processGO:00436322120.013
response to inorganic substanceGO:00100351270.013
tripartite regional subdivisionGO:000735120.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.013
epithelial cell differentiationGO:00308551410.013
cell growthGO:00160491600.013
negative regulation of phosphorus metabolic processGO:00105632670.013
single organism reproductive processGO:0044702980.012
Human
regulation of reactive oxygen species metabolic processGO:2000377410.012
prostate gland morphogenesisGO:006051210.012
regulation of transmembrane transporter activityGO:0022898740.012
peptidyl tyrosine modificationGO:00182121700.012
rho protein signal transductionGO:0007266260.012
cellular calcium ion homeostasisGO:00068741170.012
drinking behaviorGO:004275610.012
memoryGO:000761330.012
regulation of ion transmembrane transportGO:00347651320.012
t cell activationGO:0042110990.012
synaptic transmission involved in micturitionGO:006008420.012
anterior posterior axis specification embryoGO:000859520.012
salivary gland morphogenesisGO:000743540.012
purine nucleoside triphosphate metabolic processGO:00091444120.012
single organism nuclear importGO:19025931040.012
negative regulation of phosphate metabolic processGO:00459362670.012
mapk cascadeGO:00001652880.012
positive regulation of protein transportGO:00512221350.012
purine ribonucleoside metabolic processGO:00461284370.012
membrane organizationGO:00610242920.012
cytosolic calcium ion homeostasisGO:0051480890.012
heart contractionGO:0060047620.012
modification dependent protein catabolic processGO:00199412090.012
positive regulation of intracellular transportGO:00323881040.012
regulation of actin filament based processGO:00329701410.012
regulation of response to external stimulusGO:00321012220.012
spermatid developmentGO:000728640.012
blastoderm segmentationGO:000735020.012
regulation of cell growthGO:00015581350.012
peripheral nervous system developmentGO:000742220.012
reactive oxygen species metabolic processGO:0072593750.012
endocytosisGO:00068971590.012
reactive oxygen species biosynthetic processGO:190340940.012
photoreceptor cell differentiationGO:004653020.012
defense response to other organismGO:00985421290.012
positive regulation of proteolysisGO:00458621420.012
cellular component disassemblyGO:0022411920.012
calcium ion transmembrane transportGO:0070588760.012
protein localization to nucleusGO:00345041360.012
regulation of reactive oxygen species biosynthetic processGO:190342630.011
visual behaviorGO:000763220.011
cell morphogenesis involved in differentiationGO:00009041440.011
negative regulation of developmental processGO:00510932470.011
viral processGO:00160321460.011
response to nitrogen compoundGO:19016981840.011
ubiquitin dependent protein catabolic processGO:00065112060.011
histone modificationGO:00165702510.011
protein targeting to nucleusGO:00447441040.011
regulation of protein ubiquitinationGO:0031396950.011
lipid biosynthetic processGO:00086101770.011
ossificationGO:00015031210.011
negative regulation of intracellular signal transductionGO:19025321830.011
single organism cell adhesionGO:00986021790.011
leukocyte migrationGO:00509001070.011
peptidyl tyrosine phosphorylationGO:00181081700.011
positive regulation of mapk cascadeGO:00434101900.011
cd8 positive alpha beta t cell differentiation involved in immune responseGO:000230210.011
regulation of cardiac muscle tissue growthGO:005502140.011
response to virusGO:00096151260.011
negative regulation of acetylcholine gated cation channel activityGO:190304910.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
response to axon injuryGO:004867810.011
oocyte developmentGO:004859910.011
lipid transportGO:0006869900.011
cellular response to abiotic stimulusGO:00712141170.011
nucleoside triphosphate catabolic processGO:00091433940.011
negative regulation of cell fate commitmentGO:001045430.011
regenerationGO:003109940.011
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.011
positive regulation of cell motilityGO:20001471770.011
positive regulation of apoptotic signaling pathwayGO:2001235700.011
behavioral response to ethanolGO:004814920.011
sequestering of calcium ionGO:0051208170.011
associative learningGO:000830610.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
regulation of intracellular protein transportGO:00331571230.011
purine nucleotide catabolic processGO:00061954050.011
positive regulation of organelle organizationGO:00106381950.011
cellular response to organic cyclic compoundGO:00714071270.011
neurogenesisGO:00220081690.011
segmentationGO:003528240.011
regulation of blood circulationGO:1903522590.011
sensory perception of light stimulusGO:0050953350.011
ribonucleoside triphosphate metabolic processGO:00091994120.011
actin cytoskeleton organizationGO:00300362070.011
short chain fatty acid importGO:001591310.011
response to organonitrogen compoundGO:00102431560.011
regulation of calcium ion transport into cytosolGO:0010522330.011
gtp metabolic processGO:00460392390.011
cellular response to nitrogen compoundGO:19016991440.010
response to radiationGO:00093141510.010
positive regulation of organic acid transportGO:003289230.010
alpha ketoglutarate transportGO:001574210.010
purine nucleoside triphosphate catabolic processGO:00091463920.010
regulation of cellular response to growth factor stimulusGO:0090287760.010
dna repairGO:00062811980.010
defense response to fungusGO:005083240.010
positive regulation of catabolic processGO:00098963100.010
reactive nitrogen species metabolic processGO:200105730.010
endomembrane system organizationGO:00102561960.010
protein localization to membraneGO:00726571600.010
vasculature developmentGO:00019441810.010
regulation of meiotic cell cycleGO:005144540.010
micturitionGO:006007330.010
oocyte differentiationGO:000999420.010
protein importGO:00170381300.010
regulation of vesicle mediated transportGO:00606271300.010
positive regulation of digestive system processGO:006045620.010
negative regulation of catabolic processGO:00098951040.010
positive regulation of cellular catabolic processGO:00313312840.010
posttranscriptional regulation of gene expressionGO:00106082130.010
positive regulation of cellular component biogenesisGO:00440891580.010
organophosphate biosynthetic processGO:00904071630.010

KLK2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.062
sensory system diseaseDOID:00501552030.062
eye and adnexa diseaseDOID:14921500.046
eye diseaseDOID:56141490.046
retinal diseaseDOID:56791180.030
musculoskeletal system diseaseDOID:172230.025
night blindnessDOID:8499100.021
disease of metabolismDOID:00146672950.019
disease of cellular proliferationDOID:145661740.016
congenital stationary night blindnessDOID:005053480.014
muscle tissue diseaseDOID:661130.013
muscular diseaseDOID:00800001140.013
organ system cancerDOID:00506861640.013
cancerDOID:1621670.013
inherited metabolic disorderDOID:6552420.012
cardiovascular system diseaseDOID:12871060.012
neurodegenerative diseaseDOID:12891020.011
central nervous system diseaseDOID:3311860.011
retinal degenerationDOID:8466890.011
immune system diseaseDOID:29141550.011
heart diseaseDOID:114680.011