Homo sapiens

23 known processes

KLK4

kallikrein-related peptidase 4

(Aliases: PSTS,MGC116827,EMSP,MGC116828,PRSS17,ARM1,KLK-L1,EMSP1,AI2A1)

KLK4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
epithelium developmentGO:00604292270.088
Human
epidermis morphogenesisGO:004873030.074
Human
post embryonic developmentGO:000979120.064
organ formationGO:004864530.055
matingGO:000761810.050
Human
anatomical structure formation involved in morphogenesisGO:00486462840.044
cardiovascular system developmentGO:00723582620.043
epithelial cell differentiationGO:00308551410.042
multicellular organismal agingGO:001025930.042
locomotory behaviorGO:000762610.040
positive regulation of developmental processGO:00510943140.040
regulation of cell differentiationGO:00455953930.039
circulatory system developmentGO:00723592620.038
cellular component morphogenesisGO:00329893140.037
inseminationGO:000732010.036
Human
lipid metabolic processGO:00066293810.035
determination of adult lifespanGO:000834020.035
female gamete generationGO:000729220.035
hindbrain developmentGO:003090230.034
cell morphogenesisGO:00009022960.034
regulation of cellular ketone metabolic processGO:0010565500.034
cell developmentGO:00484683280.033
regulation of cellular amino acid metabolic processGO:000652160.032
segmentationGO:003528240.032
organ morphogenesisGO:00098871470.032
vasculature developmentGO:00019441810.032
positive regulation of aldosterone metabolic processGO:003234620.031
oogenesisGO:004847720.031
regulation of cellular component movementGO:00512703340.031
regulation of anatomical structure morphogenesisGO:00226032860.031
nervous system developmentGO:00073992930.031
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.029
positive regulation of cell differentiationGO:00455972110.029
regulation of cellular amine metabolic processGO:0033238110.029
positive regulation of cellular amino acid metabolic processGO:004576430.029
purine ribonucleoside metabolic processGO:00461284370.029
cellular ketone metabolic processGO:0042180800.029
cellular amino acid metabolic processGO:00065201160.029
regulation of locomotionGO:00400123290.028
negative regulation of multicellular organismal processGO:00512413170.028
positive regulation of cell proliferationGO:00082843010.027
positive regulation of hydrolase activityGO:00513453310.026
small gtpase mediated signal transductionGO:0007264780.026
cellular response to endogenous stimulusGO:00714953360.026
amine metabolic processGO:0009308440.026
somitogenesisGO:000175620.026
cell cell signalingGO:00072671550.026
regulation of cell cycleGO:00517263930.025
negative regulation of protein metabolic processGO:00512483910.025
positive regulation of steroid hormone biosynthetic processGO:009003120.025
positive regulation of cellular amine metabolic processGO:003324070.025
regulation of cell migrationGO:00303342890.025
protein processingGO:00164852260.025
Human
epithelial cell migrationGO:00106311190.025
Human
morphogenesis of an epitheliumGO:0002009600.025
Human
protein catabolic processGO:00301633250.024
Mouse
biological adhesionGO:00226103310.024
head developmentGO:00603221080.024
nucleoside triphosphate metabolic processGO:00091414220.023
cell fate determinationGO:000170930.023
purine nucleoside triphosphate catabolic processGO:00091463920.023
anterior posterior axis specificationGO:000994820.022
cellular amine metabolic processGO:0044106410.022
hair follicle morphogenesisGO:003106920.022
limbic system developmentGO:002176130.022
epithelium migrationGO:00901321190.022
Human
cell adhesionGO:00071553250.022
compound eye developmentGO:004874910.022
cell projection organizationGO:00300302520.022
regulation of cell motilityGO:20001452990.022
response to hormoneGO:00097251750.022
negative regulation of developmental processGO:00510932470.021
central nervous system developmentGO:00074171230.021
peripheral nervous system developmentGO:000742220.021
single organism cellular localizationGO:19025803320.021
ribonucleoside catabolic processGO:00424544060.021
blastoderm segmentationGO:000735020.021
purine ribonucleoside triphosphate catabolic processGO:00092073910.021
metencephalon developmentGO:002203720.021
cellular response to dna damage stimulusGO:00069743790.021
purine nucleoside triphosphate metabolic processGO:00091444120.021
cellular macromolecule catabolic processGO:00442653800.021
positive regulation of aldosterone biosynthetic processGO:003234920.021
neuromuscular junction developmentGO:000752830.020
regenerationGO:003109940.020
growthGO:00400072020.020
immune responseGO:00069553070.020
oocyte differentiationGO:000999420.020
negative regulation of cellular protein metabolic processGO:00322693530.020
response to lipidGO:00339932060.019
negative regulation of apoptotic processGO:00430663160.019
system processGO:00030083490.019
generation of neuronsGO:00486991520.019
single organism membrane organizationGO:00448022680.019
oocyte developmentGO:004859910.019
blood vessel developmentGO:00015681720.019
brain developmentGO:0007420970.019
neuron fate commitmentGO:004866320.019
organophosphate catabolic processGO:00464344300.019
positive regulation of odontogenesisGO:004248230.019
embryonic forelimb morphogenesisGO:003511540.019
forelimb morphogenesisGO:003513640.019
positive regulation of cellular catabolic processGO:00313312840.019
purine ribonucleoside triphosphate metabolic processGO:00092054110.019
ras protein signal transductionGO:0007265730.019
negative regulation of protein modification processGO:00314002000.018
epidermis developmentGO:0008544590.018
Human
negative regulation of cellular component movementGO:00512711060.018
regulation of proteolysisGO:00301622930.018
mitotic cell cycleGO:00002783260.018
regulation of gtpase activityGO:00430871800.018
regulation of nervous system developmentGO:0051960880.018
purine containing compound catabolic processGO:00725234110.018
positive regulation of proteolysisGO:00458621420.018
negative regulation of phosphorus metabolic processGO:00105632670.018
spermatid differentiationGO:004851540.018
cell morphogenesis involved in differentiationGO:00009041440.018
glycosyl compound catabolic processGO:19016584130.018
cardiac right ventricle morphogenesisGO:000321530.018
cytoplasmic transportGO:00164823790.018
purine nucleotide catabolic processGO:00061954050.018
guanosine containing compound catabolic processGO:19010692390.018
negative regulation of cell deathGO:00605483450.018
endomembrane system organizationGO:00102561960.017
protein maturationGO:00516042330.017
Human
enzyme linked receptor protein signaling pathwayGO:00071673030.017
regulation of hormone levelsGO:00108171250.017
nucleoside triphosphate catabolic processGO:00091433940.017
ribonucleoside triphosphate catabolic processGO:00092033910.017
regulation of cell developmentGO:00602841610.017
lipid biosynthetic processGO:00086101770.017
hematopoietic or lymphoid organ developmentGO:00485341860.017
negative regulation of cellular component organizationGO:00511292350.017
cellular protein catabolic processGO:00442572610.017
negative regulation of catalytic activityGO:00430863350.017
post embryonic organ developmentGO:004856910.017
regulation of transferase activityGO:00513383550.017
actin filament based processGO:00300292240.017
adult locomotory behaviorGO:000834410.017
positive regulation of phosphorylationGO:00423273940.017
regulation of cytoskeleton organizationGO:00514931770.017
circadian behaviorGO:004851220.017
associative learningGO:000830610.017
cranial nerve developmentGO:002154540.017
regulation of kinase activityGO:00435493140.017
blood vessel morphogenesisGO:00485141620.017
photoreceptor cell differentiationGO:004653020.017
transmembrane transportGO:00550853990.016
ribonucleotide catabolic processGO:00092614050.016
positive regulation of cellular component organizationGO:00511303760.016
negative regulation of cell cycleGO:00457861930.016
spinal cord developmentGO:002151040.016
nucleotide catabolic processGO:00091664080.016
tissue morphogenesisGO:0048729960.016
Human
negative regulation of programmed cell deathGO:00430693210.016
purine nucleoside catabolic processGO:00061523980.016
neurogenesisGO:00220081690.016
cellular response to hormone stimulusGO:00328701250.016
regulation of growthGO:00400081650.016
regulation of endopeptidase activityGO:00525481700.016
regulation of protein kinase activityGO:00458592890.016
cell part morphogenesisGO:00329901370.016
dephosphorylationGO:00163112090.016
cellular lipid metabolic processGO:00442553030.016
positive regulation of apoptotic processGO:00430652460.015
tissue migrationGO:00901301190.015
Human
rhythmic behaviorGO:000762220.015
defense responseGO:00069523150.015
purine ribonucleotide catabolic processGO:00091544040.015
nucleoside phosphate catabolic processGO:19012924120.015
gtp metabolic processGO:00460392390.015
gtp catabolic processGO:00061842370.015
negative regulation of cell proliferationGO:00082852280.015
morphogenesis of embryonic epitheliumGO:001633140.015
endothelial cell migrationGO:0043542860.015
Human
cerebellum developmentGO:002154920.015
negative regulation of phosphate metabolic processGO:00459362670.015
regulation of mitotic cell cycleGO:00073461890.015
regulation of cellular response to stressGO:00801352440.015
regulation of protein transportGO:00512232130.015
protein localization to organelleGO:00333652800.015
response to oxygen containing compoundGO:19017003690.015
spermatid developmentGO:000728640.015
negative regulation of phosphorylationGO:00423261740.015
muscle structure developmentGO:0061061980.015
regulation of cytokine productionGO:00018172320.015
negative regulation of hydrolase activityGO:00513461820.015
carbohydrate derivative biosynthetic processGO:19011372070.015
regulation of purine nucleotide metabolic processGO:19005422640.015
regulation of cell cycle processGO:00105642660.015
reproductive processGO:00224141060.015
Human
negative regulation of cell migrationGO:00303361020.015
negative regulation of testicular blood vessel morphogenesisGO:006136910.015
glycoprotein metabolic processGO:00091001100.014
regulation of cell adhesionGO:00301551660.014
mesonephric duct developmentGO:007217730.014
embryo developmentGO:00097901230.014
positive regulation of catabolic processGO:00098963100.014
regulation of vasculature developmentGO:1901342970.014
specification of organ identityGO:001009230.014
ribonucleoside triphosphate metabolic processGO:00091994120.014
positive regulation of nucleotide metabolic processGO:00459812300.014
positive regulation of tooth mineralizationGO:007017220.014
mitotic cell cycle processGO:19030472860.014
positive regulation of programmed cell deathGO:00430682490.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
cell growthGO:00160491600.014
cellular response to oxygen containing compoundGO:19017012760.014
positive regulation of transportGO:00510503360.014
ameboidal type cell migrationGO:00016671350.014
Human
membrane organizationGO:00610242920.014
neuron differentiationGO:00301821380.014
pattern specification processGO:0007389430.014
anterior posterior axis specification embryoGO:000859520.014
plasma membrane organizationGO:00070091150.014
memoryGO:000761330.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
response to abiotic stimulusGO:00096283360.014
response to fungusGO:000962040.014
cardiac muscle cell contractionGO:008600340.014
regulation of establishment of protein localizationGO:00702012420.014
negative regulation of cell differentiationGO:00455961710.014
syncytium formation by plasma membrane fusionGO:000076820.014
response to organic cyclic compoundGO:00140702040.014
regulation of peptidase activityGO:00525471800.014
regulation of purine nucleotide catabolic processGO:00331212050.014
regulation of protein localizationGO:00328802960.014
rna processingGO:00063962550.014
negative regulation of locomotionGO:00400131180.014
regulation of nucleotide metabolic processGO:00061402690.014
purine ribonucleoside catabolic processGO:00461303980.013
inner ear morphogenesisGO:004247240.013
protein localization to membraneGO:00726571600.013
actin filament based movementGO:0030048170.013
detection of chemical stimulus involved in sensory perception of sweet tasteGO:000158220.013
negative regulation of cell motilityGO:20001461040.013
microtubule based processGO:00070172100.013
hemopoiesisGO:00300971800.013
small molecule biosynthetic processGO:00442831570.013
negative regulation of protein phosphorylationGO:00019331400.013
nerve developmentGO:002167540.013
maintenance of locationGO:00512351120.013
cellular macromolecular complex assemblyGO:00346223240.013
guanosine containing compound metabolic processGO:19010682440.013
skeletal system developmentGO:0001501790.013
immune system developmentGO:00025201950.013
positive regulation of hormone biosynthetic processGO:004688640.013
regulation of cell growthGO:00015581350.013
protein ubiquitinationGO:00165673140.013
protein modification by small protein conjugationGO:00324463420.013
regulation of nucleoside metabolic processGO:00091182090.013
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.013
cell projection morphogenesisGO:00488581290.013
tissue regenerationGO:004224630.013
proteasomal protein catabolic processGO:00104981760.013
neuron developmentGO:00486661130.013
single organism cell adhesionGO:00986021790.013
positive regulation of cell deathGO:00109422630.013
regulation of dna metabolic processGO:00510521530.013
organelle assemblyGO:00709251760.013
negative regulation of cellular amino acid metabolic processGO:004576320.013
angiogenesisGO:00015251470.013
positive regulation of kinase activityGO:00336742040.013
cation transportGO:00068123310.012
regulation of cellular component biogenesisGO:00440872810.012
cell differentiation in spinal cordGO:002151510.012
stem cell differentiationGO:0048863930.012
tripartite regional subdivisionGO:000735120.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
establishment of protein localization to membraneGO:00901501210.012
non canonical wnt signaling pathway via mapk cascadeGO:003803040.012
embryonic morphogenesisGO:0048598850.012
heart field specificationGO:000312820.012
skin developmentGO:0043588760.012
Human
patterning of blood vesselsGO:000156920.012
single organismal cell cell adhesionGO:00163371480.012
complement activation alternative pathwayGO:000695710.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
regulation of synaptic plasticityGO:004816730.012
neuron projection developmentGO:00311751060.012
intracellular protein transportGO:00068862700.012
response to woundingGO:00096111680.012
secretionGO:00469032540.012
regulation of meiotic cell cycleGO:005144540.012
cation homeostasisGO:00550801890.012
sensory perception of painGO:001923340.012
regulation of gtp catabolic processGO:00331241800.012
somatic muscle developmentGO:000752510.012
dna repairGO:00062811980.012
cell aggregationGO:009874310.012
positive regulation of transferase activityGO:00513472270.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
regulation of ion transportGO:00432691890.012
heart developmentGO:0007507950.012
sequestering of metal ionGO:0051238240.012
modification dependent macromolecule catabolic processGO:00436322120.012
positive regulation of cell motilityGO:20001471770.012
histone modificationGO:00165702510.011
epidermal cell differentiationGO:0009913450.011
secretion by cellGO:00329402260.011
positive regulation of immune system processGO:00026842830.011
cellular homeostasisGO:00197251960.011
regulation of meiosisGO:004002030.011
negative regulation of cellular amine metabolic processGO:003323930.011
reactive oxygen species metabolic processGO:0072593750.011
positive regulation of gtp catabolic processGO:00331261660.011
cd8 positive alpha beta t cell activationGO:003603730.011
protein targetingGO:00066051870.011
actin mediated cell contractionGO:0070252120.011
chromatin modificationGO:00165682980.011
positive regulation of gtpase activityGO:00435471660.011
metal ion homeostasisGO:00550651690.011
regulation of protein catabolic processGO:00421761550.011
behaviorGO:00076101120.011
aortic valve developmentGO:000317630.011
posttranscriptional regulation of gene expressionGO:00106082130.011
developmental programmed cell deathGO:001062330.011
rho protein signal transductionGO:0007266260.011
thymus developmentGO:004853830.011
positive regulation of synaptic transmissionGO:005080640.011
ubiquitin dependent protein catabolic processGO:00065112060.011
myoblast fusionGO:000752010.011
negative regulation of growthGO:0045926970.011
visual behaviorGO:000763220.011
regulation of response to external stimulusGO:00321012220.011
chemotaxisGO:00069351570.011
cell divisionGO:00513011680.011
regulation of ras protein signal transductionGO:00465781550.011
protein localization to plasma membraneGO:0072659930.011
heart formationGO:006091420.011
primary neural tube formationGO:001402030.011
regulation of epithelial cell proliferationGO:00506781130.011
regulation of bindingGO:00510981110.011
nucleoside catabolic processGO:00091644080.011
cell substrate adhesionGO:00315891320.011
carbohydrate metabolic processGO:00059752070.011
forebrain neuron differentiationGO:002187930.011
cell projection assemblyGO:00300311260.011
monocarboxylic acid metabolic processGO:00327871850.011
negative regulation of intracellular signal transductionGO:19025321830.011
innate immune responseGO:00450871780.011
regulation of heart growthGO:006042040.011
positive regulation of endopeptidase activityGO:0010950840.011
covalent chromatin modificationGO:00165692540.011
modification dependent protein catabolic processGO:00199412090.011
neural tube closureGO:000184330.011
positive regulation of cellular component movementGO:00512721810.011
positive regulation of hyaluranon cable assemblyGO:190010630.011
cellular response to growth factor stimulusGO:00713631970.011
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathwayGO:003562540.011
negative regulation of organelle organizationGO:00106391260.011
microtubule cytoskeleton organizationGO:00002261760.011
chromatin organizationGO:00063253510.011
apoptotic signaling pathwayGO:00971902680.011
cytokine productionGO:00018162470.011
organelle fissionGO:00482851490.010
nucleocytoplasmic transportGO:00069131760.010
muscle tissue developmentGO:0060537620.010
ossificationGO:00015031210.010
sex determinationGO:000753030.010
postsynaptic membrane organizationGO:000194120.010
regulation of wnt signaling pathwayGO:00301111230.010
wnt signaling pathwayGO:00160551560.010
single organism reproductive processGO:0044702980.010
Human
blastocyst developmentGO:000182430.010
hormone secretionGO:0046879650.010
positive regulation of purine nucleotide catabolic processGO:00331231850.010
chemical homeostasisGO:00488783060.010
meiosis iGO:000712740.010
neural tube patterningGO:002153220.010
regulation of actin filament based processGO:00329701410.010
cardiac muscle contractionGO:0060048340.010
positive regulation of nucleoside metabolic processGO:00459791860.010
negative regulation of transferase activityGO:00513481240.010
forebrain generation of neuronsGO:002187230.010
regulation of protein maturationGO:19033171500.010
response to cytokineGO:00340972320.010
g protein coupled receptor signaling pathwayGO:00071862070.010
Human
positive regulation of protein phosphorylationGO:00019343130.010
oxidation reduction processGO:00551143960.010
regulation of neural precursor cell proliferationGO:200017740.010
response to biotic stimulusGO:00096072760.010
organonitrogen compound biosynthetic processGO:19015662000.010
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.010
response to external biotic stimulusGO:00432072610.010
single organism carbohydrate metabolic processGO:00447231930.010
regulation of ras gtpase activityGO:00323181280.010
positive regulation of organelle organizationGO:00106381950.010
pericardium developmentGO:006003920.010
metal ion transportGO:00300012720.010
forebrain regionalizationGO:002187130.010
reactive oxygen species biosynthetic processGO:190340940.010
regionalizationGO:0003002290.010
protein localization to nucleusGO:00345041360.010

KLK4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.033
nervous system diseaseDOID:8634310.025
sensory system diseaseDOID:00501552030.025
musculoskeletal system diseaseDOID:172230.019
eye and adnexa diseaseDOID:14921500.019
eye diseaseDOID:56141490.018
connective tissue diseaseDOID:651090.013
bone diseaseDOID:0080001880.013
inherited metabolic disorderDOID:6552420.013
cancerDOID:1621670.011
disease of cellular proliferationDOID:145661740.011
acquired metabolic diseaseDOID:0060158580.010
gastrointestinal system diseaseDOID:77360.007
mouth diseaseDOID:403140.003
tooth diseaseDOID:1091140.003
teeth hard tissue diseaseDOID:21480.001
amelogenesis imperfectaDOID:218770.001
dental enamel hypoplasiaDOID:69370.001