Homo sapiens

7 known processes

KLK8

kallikrein-related peptidase 8

(Aliases: NP,HNP,NRPN,TADG14,PRSS19)

KLK8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
copulationGO:000762010.985
Human
inseminationGO:000732010.836
Human
epidermis morphogenesisGO:004873030.698
Human
seminal clot liquefactionGO:007068410.577
Human
endothelial cell migrationGO:0043542860.337
Human
matingGO:000761810.274
Human
epithelial cell migrationGO:00106311190.269
Human
epithelium migrationGO:00901321190.232
Human
g protein coupled receptor signaling pathwayGO:00071862070.230
Human
ameboidal type cell migrationGO:00016671350.188
Human
epithelium developmentGO:00604292270.144
Human
cellular ketone metabolic processGO:0042180800.138
tissue migrationGO:00901301190.134
Human
cardiac muscle cell contractionGO:008600340.110
skin developmentGO:0043588760.102
Human
epidermis developmentGO:0008544590.094
Human
protein processingGO:00164852260.094
Human
protein maturationGO:00516042330.080
Human
small gtpase mediated signal transductionGO:0007264780.077
system processGO:00030083490.075
transmembrane transportGO:00550853990.073
post embryonic developmentGO:000979120.070
negative regulation of g protein coupled receptor protein signaling pathwayGO:0045744180.066
Human
cellular amino acid metabolic processGO:00065201160.066
ion transmembrane transportGO:00342203380.065
organ morphogenesisGO:00098871470.064
Human
response to organic cyclic compoundGO:00140702040.063
keratinizationGO:003142420.063
zymogen activationGO:0031638700.062
Human
regulation of cellular amino acid metabolic processGO:000652160.060
ribonucleoside catabolic processGO:00424544060.058
cellular amine metabolic processGO:0044106410.057
regulation of cellular ketone metabolic processGO:0010565500.056
response to oxygen containing compoundGO:19017003690.055
regulation of cellular component movementGO:00512703340.055
locomotory behaviorGO:000762610.054
lipid metabolic processGO:00066293810.053
positive regulation of g protein coupled receptor protein signaling pathwayGO:004574590.052
Human
ras protein signal transductionGO:0007265730.051
negative regulation of cell deathGO:00605483450.051
positive regulation of nucleotide catabolic processGO:00308131850.048
response to biotic stimulusGO:00096072760.047
regenerationGO:003109940.046
purine nucleotide catabolic processGO:00061954050.045
positive regulation of locomotionGO:00400171860.045
cation transportGO:00068123310.045
regulation of cellular amine metabolic processGO:0033238110.045
nucleoside catabolic processGO:00091644080.043
hair follicle morphogenesisGO:003106920.043
purine ribonucleoside metabolic processGO:00461284370.042
positive regulation of phosphorylationGO:00423273940.042
morphogenesis of an epitheliumGO:0002009600.042
Human
purine containing compound catabolic processGO:00725234110.041
actin mediated cell contractionGO:0070252120.041
positive regulation of mapk cascadeGO:00434101900.041
amine metabolic processGO:0009308440.041
purine ribonucleotide catabolic processGO:00091544040.040
organophosphate catabolic processGO:00464344300.040
ribonucleoside triphosphate metabolic processGO:00091994120.040
odontogenesisGO:0042476250.040
Human
regulation of nucleotide catabolic processGO:00308112050.040
actin filament based processGO:00300292240.040
nucleotide catabolic processGO:00091664080.039
positive regulation of cell motilityGO:20001471770.038
membrane organizationGO:00610242920.038
positive regulation of catabolic processGO:00098963100.038
regulation of purine nucleotide metabolic processGO:19005422640.038
purine nucleoside catabolic processGO:00061523980.038
purine nucleoside triphosphate metabolic processGO:00091444120.037
purine ribonucleoside catabolic processGO:00461303980.037
neuron deathGO:0070997650.037
Human
nucleoside phosphate catabolic processGO:19012924120.037
purine ribonucleoside triphosphate metabolic processGO:00092054110.037
tissue morphogenesisGO:0048729960.037
Human
nucleoside triphosphate catabolic processGO:00091433940.037
rho protein signal transductionGO:0007266260.037
ribonucleotide catabolic processGO:00092614050.036
positive regulation of purine nucleotide catabolic processGO:00331231850.036
response to external biotic stimulusGO:00432072610.036
cell adhesionGO:00071553250.036
regulation of transferase activityGO:00513383550.036
purine nucleoside triphosphate catabolic processGO:00091463920.036
nucleoside triphosphate metabolic processGO:00091414220.036
ribonucleoside triphosphate catabolic processGO:00092033910.036
positive regulation of cellular catabolic processGO:00313312840.035
regulation of cell motilityGO:20001452990.035
regulation of nucleoside metabolic processGO:00091182090.035
defense responseGO:00069523150.035
purine ribonucleoside triphosphate catabolic processGO:00092073910.035
muscle system processGO:0003012810.035
retina homeostasisGO:0001895420.035
female gamete generationGO:000729220.035
small molecule biosynthetic processGO:00442831570.035
single organism membrane organizationGO:00448022680.035
inorganic ion transmembrane transportGO:00986602310.034
establishment of protein localization to membraneGO:00901501210.034
signal transduction by phosphorylationGO:00230142970.034
anatomical structure formation involved in morphogenesisGO:00486462840.034
regulation of locomotionGO:00400123290.034
single organism cellular localizationGO:19025803320.034
nervous system developmentGO:00073992930.033
positive regulation of hydrolase activityGO:00513453310.033
multicellular organismal agingGO:001025930.033
cellular lipid metabolic processGO:00442553030.033
regulation of g protein coupled receptor protein signaling pathwayGO:0008277350.033
Human
regulation of mapk cascadeGO:00434082620.032
cytoplasmic transportGO:00164823790.032
cation transmembrane transportGO:00986552380.032
regulation of purine nucleotide catabolic processGO:00331212050.032
mapk cascadeGO:00001652880.032
epithelial cell differentiationGO:00308551410.032
muscle contractionGO:0006936730.032
keratinocyte differentiationGO:0030216360.031
regulation of actin filament based processGO:00329701410.031
response to other organismGO:00517072610.031
positive regulation of purine nucleotide metabolic processGO:19005442270.031
positive regulation of cellular amine metabolic processGO:003324070.031
regulation of cell differentiationGO:00455953930.031
positive regulation of cellular component organizationGO:00511303760.031
vesicle mediated transportGO:00161923710.031
positive regulation of nucleoside metabolic processGO:00459791860.030
striated muscle contractionGO:0006941520.030
determination of adult lifespanGO:000834020.030
glycosyl compound catabolic processGO:19016584130.029
actin filament based movementGO:0030048170.029
cellular component morphogenesisGO:00329893140.029
cell projection organizationGO:00300302520.029
oogenesisGO:004847720.029
positive regulation of gtpase activityGO:00435471660.029
multicellular organismal signalingGO:0035637340.029
positive regulation of cell migrationGO:00303351720.028
gtp catabolic processGO:00061842370.028
nitrogen compound transportGO:00717051910.028
chemical homeostasisGO:00488783060.028
regulation of cell migrationGO:00303342890.028
regulation of gtpase activityGO:00430871800.028
positive regulation of nucleotide metabolic processGO:00459812300.027
single organism reproductive processGO:0044702980.027
Human
anion transportGO:00068201610.027
positive regulation of cellular amino acid metabolic processGO:004576430.027
cation homeostasisGO:00550801890.027
single organism cell adhesionGO:00986021790.027
lipid biosynthetic processGO:00086101770.026
regulation of gtp catabolic processGO:00331241800.026
gtp metabolic processGO:00460392390.026
negative regulation of apoptotic processGO:00430663160.026
regulation of cellular component biogenesisGO:00440872810.026
neuromuscular junction developmentGO:000752830.026
negative regulation of cellular protein metabolic processGO:00322693530.025
regulation of system processGO:00440571010.025
regulation of nucleotide metabolic processGO:00061402690.025
tissue regenerationGO:004224630.024
reproductive processGO:00224141060.024
Human
organic hydroxy compound metabolic processGO:19016151470.024
immune responseGO:00069553070.024
fatty acid metabolic processGO:00066311150.024
blood vessel developmentGO:00015681720.023
negative regulation of catalytic activityGO:00430863350.023
guanosine containing compound catabolic processGO:19010692390.023
regulation of cell cycle processGO:00105642660.023
epidermal cell differentiationGO:0009913450.023
negative regulation of programmed cell deathGO:00430693210.022
skin morphogenesisGO:004358960.022
Human
posttranscriptional regulation of gene expressionGO:00106082130.022
cell developmentGO:00484683280.022
enzyme linked receptor protein signaling pathwayGO:00071673030.022
cellular macromolecular complex assemblyGO:00346223240.022
epithelial cell proliferationGO:00506731280.022
regulation of membrane potentialGO:0042391950.022
guanosine containing compound metabolic processGO:19010682440.022
wnt signaling pathwayGO:00160551560.022
single organismal cell cell adhesionGO:00163371480.022
regulation of cytoskeleton organizationGO:00514931770.022
angiogenesisGO:00015251470.022
cellular response to organic cyclic compoundGO:00714071270.022
cardiovascular system developmentGO:00723582620.022
ion homeostasisGO:00508012300.022
regulation of protein kinase activityGO:00458592890.022
response to lipidGO:00339932060.021
memoryGO:000761330.021
positive regulation of protein phosphorylationGO:00019343130.021
positive regulation of cell differentiationGO:00455972110.021
biological adhesionGO:00226103310.021
negative regulation of protein metabolic processGO:00512483910.021
regulation of anatomical structure morphogenesisGO:00226032860.021
regulation of kinase activityGO:00435493140.021
carboxylic acid biosynthetic processGO:0046394970.021
positive regulation of developmental processGO:00510943140.021
regulation of cytokine productionGO:00018172320.021
cellular response to dna damage stimulusGO:00069743790.021
positive regulation of organelle organizationGO:00106381950.021
positive regulation of cellular component movementGO:00512721810.020
action potentialGO:0001508340.020
circulatory system developmentGO:00723592620.020
regulation of cell cycleGO:00517263930.020
protein catabolic processGO:00301633250.020
circulatory system processGO:00030131130.020
intracellular protein transportGO:00068862700.020
cellular response to oxygen containing compoundGO:19017012760.019
hair cycleGO:0042633280.019
apoptotic signaling pathwayGO:00971902680.019
morphogenesis of embryonic epitheliumGO:001633140.019
cardiac muscle contractionGO:0060048340.019
regulation of protein stabilityGO:0031647870.019
protein oligomerizationGO:00512591730.019
positive regulation of gtp catabolic processGO:00331261660.019
mitotic cell cycle processGO:19030472860.019
blastoderm segmentationGO:000735020.019
positive regulation of cellular component biogenesisGO:00440891580.019
positive regulation of transportGO:00510503360.018
mitotic cell cycleGO:00002783260.018
organic acid biosynthetic processGO:0016053970.018
positive regulation of protein kinase activityGO:00458601900.018
protein localization to plasma membraneGO:0072659930.018
response to oxidative stressGO:00069791210.018
cytokine productionGO:00018162470.018
response to abiotic stimulusGO:00096283360.018
reactive oxygen species metabolic processGO:0072593750.018
regulation of ion homeostasisGO:2000021730.018
anatomical structure homeostasisGO:00602491000.018
secretion by cellGO:00329402260.018
neurogenesisGO:00220081690.018
endomembrane system organizationGO:00102561960.018
regulation of cell adhesionGO:00301551660.018
negative regulation of multicellular organismal processGO:00512413170.018
cell junction organizationGO:0034330790.018
sensory perception of painGO:001923340.018
regulation of response to external stimulusGO:00321012220.017
single organism carbohydrate metabolic processGO:00447231930.017
growthGO:00400072020.017
viral life cycleGO:00190581320.017
regulation of cellular response to stressGO:00801352440.017
protein localization to membraneGO:00726571600.017
peripheral nervous system developmentGO:000742220.017
cell morphogenesisGO:00009022960.017
reactive oxygen species biosynthetic processGO:190340940.017
innate immune responseGO:00450871780.017
regulation of sequence specific dna binding transcription factor activityGO:00510902110.017
metal ion transportGO:00300012720.017
carbohydrate metabolic processGO:00059752070.017
positive regulation of cell deathGO:00109422630.017
alcohol metabolic processGO:00060661140.017
chromatin organizationGO:00063253510.017
oocyte developmentGO:004859910.016
regulation of proteolysisGO:00301622930.016
regulation of reactive oxygen species metabolic processGO:2000377410.016
cell cycle phase transitionGO:00447701730.016
protein acylationGO:00435431380.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
regulation of small gtpase mediated signal transductionGO:00510561560.016
defense response to fungusGO:005083240.016
positive regulation of ras gtpase activityGO:00323201170.016
response to nitrogen compoundGO:19016981840.016
organonitrogen compound biosynthetic processGO:19015662000.016
positive regulation of apoptotic processGO:00430652460.016
mitotic cell cycle phase transitionGO:00447721620.016
positive regulation of immune system processGO:00026842830.016
neurological system processGO:00508771630.016
rhythmic behaviorGO:000762220.016
organelle assemblyGO:00709251760.015
organic hydroxy compound biosynthetic processGO:1901617710.015
central nervous system developmentGO:00074171230.015
regulation of heart contractionGO:0008016500.015
regulation of protein localizationGO:00328802960.015
multicellular organismal response to stressGO:003355510.015
inorganic cation transmembrane transportGO:00986621940.015
monocarboxylic acid metabolic processGO:00327871850.015
positive regulation of transferase activityGO:00513472270.015
associative learningGO:000830610.015
segmentationGO:003528240.015
regulation of apoptotic signaling pathwayGO:20012331750.015
protein localization to organelleGO:00333652800.015
response to cytokineGO:00340972320.015
oxidation reduction processGO:00551143960.015
response to organonitrogen compoundGO:00102431560.015
regulation of intracellular transportGO:00323861950.015
multi organism reproductive processGO:0044703540.015
Human
regulation of multi organism processGO:00439001570.015
cell fate determinationGO:000170930.015
regulation of ras protein signal transductionGO:00465781550.015
negative regulation of phosphorus metabolic processGO:00105632670.015
monovalent inorganic cation transportGO:00156721280.015
regulation of i kappab kinase nf kappab signalingGO:00431221620.015
carboxylic acid transportGO:0046942630.015
regulation of blood circulationGO:1903522590.015
cell activationGO:00017752130.015
response to fungusGO:000962040.014
positive regulation of kinase activityGO:00336742040.014
positive regulation of cell proliferationGO:00082843010.014
sodium ion transmembrane transportGO:0035725590.014
blood vessel morphogenesisGO:00485141620.014
chromatin modificationGO:00165682980.014
cell growthGO:00160491600.014
tissue homeostasisGO:0001894630.014
response to metal ionGO:0010038840.014
spermatid differentiationGO:004851540.014
divalent inorganic cation transportGO:00725111580.014
compound eye developmentGO:004874910.014
sequestering of metal ionGO:0051238240.014
av node cell to bundle of his cell communicationGO:008606740.014
negative regulation of cellular amine metabolic processGO:003323930.014
maintenance of locationGO:00512351120.014
melanin metabolic processGO:000658210.014
negative regulation of transportGO:00510511760.014
protein modification by small protein conjugationGO:00324463420.014
multi organism cellular processGO:00447641560.014
negative regulation of protein modification processGO:00314002000.014
positive regulation of rho gtpase activityGO:0032321560.014
spermatid developmentGO:000728640.014
cell cell signalingGO:00072671550.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
covalent chromatin modificationGO:00165692540.013
hormone metabolic processGO:0042445610.013
vasculature developmentGO:00019441810.013
cellular macromolecule catabolic processGO:00442653800.013
interspecies interaction between organismsGO:00444191560.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
metal ion homeostasisGO:00550651690.013
regulation of cardiac muscle contractionGO:0055117330.013
regulation of endopeptidase activityGO:00525481700.013
regulation of actin cytoskeleton organizationGO:00329561160.013
regulation of protein catabolic processGO:00421761550.013
i kappab kinase nf kappab signalingGO:00072491660.013
response to bacteriumGO:00096171440.013
microtubule based processGO:00070172100.013
cellular protein catabolic processGO:00442572610.013
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.013
embryonic epithelial tube formationGO:000183840.013
adult locomotory behaviorGO:000834410.013
regulation of protein maturationGO:19033171500.013
carbohydrate derivative biosynthetic processGO:19011372070.013
monocarboxylic acid biosynthetic processGO:0072330670.013
histone modificationGO:00165702510.013
cellular metal ion homeostasisGO:00068751460.013
negative regulation of cell proliferationGO:00082852280.013
plasma membrane organizationGO:00070091150.013
cellular chemical homeostasisGO:00550821800.013
regulation of cell cycle phase transitionGO:19019871260.013
regulation of protein serine threonine kinase activityGO:00719001790.013
canonical wnt signaling pathwayGO:00600701160.013
cellular cation homeostasisGO:00300031630.013
positive regulation of programmed cell deathGO:00430682490.013
regulation of establishment of protein localizationGO:00702012420.012
lymphocyte activationGO:00466491330.012
negative regulation of phosphate metabolic processGO:00459362670.012
cellular response to cytokine stimulusGO:00713451810.012
circadian behaviorGO:004851220.012
cell morphogenesis involved in differentiationGO:00009041440.012
brain developmentGO:0007420970.012
organophosphate biosynthetic processGO:00904071630.012
negative regulation of cell cycleGO:00457861930.012
regulation of ras gtpase activityGO:00323181280.012
regulation of striated muscle contractionGO:0006942370.012
viral processGO:00160321460.012
immune effector processGO:00022521590.012
negative regulation of protein processingGO:00109551420.012
regulation of cell activationGO:00508651250.012
endocytosisGO:00068971590.012
visual behaviorGO:000763220.012
actin filament organizationGO:00070151280.012
regulation of vasculature developmentGO:1901342970.012
regulation of secretion by cellGO:19035301770.012
secretionGO:00469032540.012
oocyte differentiationGO:000999420.012
defense response to other organismGO:00985421290.012
negative regulation of developmental processGO:00510932470.012
organic acid transportGO:0015849650.012
peptidyl tyrosine modificationGO:00182121700.012
regulation of mitotic cell cycleGO:00073461890.012
cellular response to endogenous stimulusGO:00714953360.012
regulation of rho protein signal transductionGO:0035023790.012
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.012
sex determinationGO:000753030.012
regulation of secretionGO:00510461940.012
organic anion transportGO:00157111030.012
pulmonary valve formationGO:000319310.012
anion transmembrane transportGO:0098656760.012
dephosphorylationGO:00163112090.012
negative regulation of cellular component organizationGO:00511292350.012
calcium ion transportGO:00068161470.012
somatic stem cell maintenanceGO:003501940.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
heart processGO:0003015620.012
cell part morphogenesisGO:00329901370.012
negative regulation of hydrolase activityGO:00513461820.012
response to inorganic substanceGO:00100351270.012
peptidyl lysine modificationGO:00182051440.012
sensory perceptionGO:00076001030.011
chemotaxisGO:00069351570.011
protein ubiquitinationGO:00165673140.011
mitochondrion organizationGO:00070051560.011
cellular calcium ion homeostasisGO:00068741170.011
reactive nitrogen species metabolic processGO:200105730.011
regulation of epithelial cell proliferationGO:00506781130.011
odontogenesis of dentin containing toothGO:0042475100.011
Human
blood circulationGO:00080151130.011
actin cytoskeleton organizationGO:00300362070.011
cellular response to nitrogen compoundGO:19016991440.011
response to radiationGO:00093141510.011
positive regulation of protein serine threonine kinase activityGO:00719021190.011
fertilizationGO:0009566120.011
Human
protein acetylationGO:00064731160.011
proteolysis involved in cellular protein catabolic processGO:00516032440.011
cellular hormone metabolic processGO:0034754410.011
divalent metal ion transportGO:00708381520.011
positive regulation of immune responseGO:00507781590.011
dna repairGO:00062811980.011
regulation of immune responseGO:00507762010.011
behaviorGO:00076101120.011
nuclear transportGO:00511691790.011
positive regulation of cell cycle processGO:00900681060.011
serotonin transportGO:000683730.011
head developmentGO:00603221080.011
regulation of cell divisionGO:00513021160.011
visual learningGO:000854210.011
calcium ion homeostasisGO:00550741220.011
regulation of transmembrane transportGO:00347621390.011
negative regulation of proteolysisGO:00458611320.011
regulation of protein transportGO:00512232130.011
regulation of cytoplasmic transportGO:19036491490.011
regulation of rho gtpase activityGO:0032319660.011
positive regulation of epithelial cell proliferationGO:0050679650.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
negative regulation of catabolic processGO:00098951040.011
negative regulation of cell cycle processGO:00109481210.011
cellular ion homeostasisGO:00068731680.011
cardiac muscle cell action potentialGO:0086001230.011
response to oxygen levelsGO:00704821000.011
atp metabolic processGO:00460341760.011
regulation of map kinase activityGO:00434051080.011
regulation of meiotic cell cycleGO:005144540.011
golgi to plasma membrane cftr protein transportGO:004300010.011
protein targetingGO:00066051870.011
cell divisionGO:00513011680.010
modification dependent protein catabolic processGO:00199412090.010
intrinsic apoptotic signaling pathwayGO:00971931270.010
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.010
regulation of viral processGO:00507921030.010
regulation of growthGO:00400081650.010
regulation of protein complex assemblyGO:00432541470.010
response to woundingGO:00096111680.010
response to hormoneGO:00097251750.010
regulation of mitotic cell cycle phase transitionGO:19019901180.010
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.010
regulation of muscle system processGO:0090257530.010
wound healingGO:00420601150.010
reproductionGO:0000003630.010
Human
steroid metabolic processGO:0008202940.010
nucleocytoplasmic transportGO:00069131760.010
negative regulation of cell differentiationGO:00455961710.010
cellular response to organonitrogen compoundGO:00714171240.010
regulation of peptidase activityGO:00525471800.010
nucleoside monophosphate metabolic processGO:00091231910.010

KLK8 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.038
sensory system diseaseDOID:00501552030.030
nervous system diseaseDOID:8634310.030
disease of metabolismDOID:00146672950.026
central nervous system diseaseDOID:3311860.022
connective tissue diseaseDOID:651090.017
eye and adnexa diseaseDOID:14921500.015
integumentary system diseaseDOID:16430.014
bone diseaseDOID:0080001880.014
disease of cellular proliferationDOID:145661740.013
cancerDOID:1621670.013
inherited metabolic disorderDOID:6552420.013
auditory system diseaseDOID:2742530.012
organ system cancerDOID:00506861640.012
neurodegenerative diseaseDOID:12891020.010