Homo sapiens

48 known processes

TK1

thymidine kinase 1, soluble

(Aliases: TK2)

TK1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein heterotetramerizationGO:005129030.966
regulation of cell cycleGO:00517263930.886
mitotic cell cycle phase transitionGO:00447721620.883
cellular response to dna damage stimulusGO:00069743790.864
negative regulation of interleukin 8 secretionGO:200048320.841
purine containing compound catabolic processGO:00725234110.804
mitotic cell cycle processGO:19030472860.730
purine ribonucleoside triphosphate metabolic processGO:00092054110.711
negative regulation of protein maturationGO:19033181420.684
cytokinesisGO:0000910960.624
response to abiotic stimulusGO:00096283360.604
cellular response to glucocorticoid stimulusGO:007138540.601
negative regulation of protein processingGO:00109551420.551
purine nucleoside triphosphate catabolic processGO:00091463920.534
vasculature developmentGO:00019441810.471
dna damage checkpointGO:0000077680.464
regulation of cellular response to stressGO:00801352440.446
regulation of sequence specific dna binding transcription factor activityGO:00510902110.445
negative regulation of protein metabolic processGO:00512483910.438
nucleoside triphosphate catabolic processGO:00091433940.412
negative regulation of catalytic activityGO:00430863350.385
response to oxygen containing compoundGO:19017003690.372
neutrophil clearanceGO:009735010.371
nucleoside monophosphate metabolic processGO:00091231910.370
Mouse
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.364
negative regulation of peptidase activityGO:0010466910.359
ribonucleoside monophosphate metabolic processGO:00091611870.359
nucleoside triphosphate metabolic processGO:00091414220.349
cell cycle phase transitionGO:00447701730.339
epithelial cell differentiationGO:00308551410.338
ribonucleoside triphosphate catabolic processGO:00092033910.333
dna repairGO:00062811980.330
regulation of mitotic cell cycleGO:00073461890.330
cell divisionGO:00513011680.324
positive regulation of synaptic transmissionGO:005080640.316
regulation of cell cycle processGO:00105642660.315
purine ribonucleotide catabolic processGO:00091544040.315
mitotic cell cycleGO:00002783260.313
purine nucleoside catabolic processGO:00061523980.309
cellular response to endogenous stimulusGO:00714953360.304
cell morphogenesisGO:00009022960.278
negative regulation of cell cycleGO:00457861930.273
cellular component morphogenesisGO:00329893140.271
nucleoside catabolic processGO:00091644080.270
negative regulation of cell differentiationGO:00455961710.254
purine nucleotide catabolic processGO:00061954050.252
chromosome segregationGO:00070591140.247
negative regulation of multicellular organismal processGO:00512413170.245
nucleoside phosphate catabolic processGO:19012924120.245
negative regulation of protein modification processGO:00314002000.235
nuclear divisionGO:00002801280.230
multicellular organismal agingGO:001025930.227
ribonucleoside catabolic processGO:00424544060.223
regulation of protein maturationGO:19033171500.219
regulation of endopeptidase activityGO:00525481700.213
ribonucleotide catabolic processGO:00092614050.212
purine ribonucleoside monophosphate metabolic processGO:00091671860.212
regulation of bindingGO:00510981110.209
dna biosynthetic processGO:0071897400.209
peptidyl serine phosphorylationGO:00181051010.206
negative regulation of protein secretionGO:0050709290.204
purine ribonucleoside metabolic processGO:00461284370.202
cell cycle g1 s phase transitionGO:0044843800.198
organ morphogenesisGO:00098871470.191
negative regulation of proteolysisGO:00458611320.190
neuromuscular junction developmentGO:000752830.180
protein processingGO:00164852260.178
negative regulation of hydrolase activityGO:00513461820.177
purine nucleoside triphosphate metabolic processGO:00091444120.174
mapk cascadeGO:00001652880.170
response to radiationGO:00093141510.170
response to growth factorGO:00708482050.169
purine ribonucleoside triphosphate catabolic processGO:00092073910.168
negative regulation of phosphate metabolic processGO:00459362670.168
ribonucleoside triphosphate metabolic processGO:00091994120.166
actin filament based processGO:00300292240.163
organelle fissionGO:00482851490.160
ion homeostasisGO:00508012300.159
nucleotide catabolic processGO:00091664080.155
regulation of mapk cascadeGO:00434082620.154
cellular response to growth factor stimulusGO:00713631970.149
negative regulation of cell deathGO:00605483450.147
negative regulation of mitotic cell cycleGO:00459301020.146
negative regulation of phosphorylationGO:00423261740.146
glycosyl compound catabolic processGO:19016584130.146
signal transduction in response to dna damageGO:0042770570.145
organophosphate catabolic processGO:00464344300.143
dna dependent dna replicationGO:0006261440.142
purine nucleoside monophosphate metabolic processGO:00091261860.141
chromatin modificationGO:00165682980.136
regulation of proteolysisGO:00301622930.134
regulation of cell cycle phase transitionGO:19019871260.133
atp metabolic processGO:00460341760.132
response to other organismGO:00517072610.132
cellular protein complex assemblyGO:00436231880.129
negative regulation of developmental processGO:00510932470.128
negative regulation of phosphorus metabolic processGO:00105632670.126
response to metal ionGO:0010038840.125
cell developmentGO:00484683280.125
response to inorganic substanceGO:00100351270.125
anatomical structure formation involved in morphogenesisGO:00486462840.123
deoxyribose phosphate metabolic processGO:001969260.122
purine nucleoside monophosphate catabolic processGO:00091281580.122
positive regulation of cellular amine metabolic processGO:003324070.118
covalent chromatin modificationGO:00165692540.116
negative regulation of cell cycle phase transitionGO:1901988890.113
viral processGO:00160321460.111
determination of adult lifespanGO:000834020.111
membrane organizationGO:00610242920.111
dna replicationGO:00062601160.110
cell morphogenesis involved in differentiationGO:00009041440.105
positive regulation of organelle organizationGO:00106381950.101
immune responseGO:00069553070.101
positive regulation of cellular catabolic processGO:00313312840.099
protein modification by small protein conjugationGO:00324463420.099
positive regulation of hydrolase activityGO:00513453310.099
regulation of cysteine type endopeptidase activityGO:20001161270.099
myosin filament assemblyGO:003103420.098
positive regulation of transferase activityGO:00513472270.097
positive regulation of transportGO:00510503360.096
regulation of protein processingGO:00706131500.094
response to cytokineGO:00340972320.093
response to organic cyclic compoundGO:00140702040.092
dna integrity checkpointGO:0031570710.089
positive regulation of catabolic processGO:00098963100.087
response to light stimulusGO:0009416870.086
protein catabolic processGO:00301633250.082
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.082
double strand break repairGO:00063021010.081
response to uvGO:0009411730.081
post embryonic developmentGO:000979120.080
negative regulation of programmed cell deathGO:00430693210.080
cellular amino acid metabolic processGO:00065201160.080
regulation of cell cycle g1 s phase transitionGO:1902806420.077
dna recombinationGO:0006310770.076
negative regulation of organelle organizationGO:00106391260.076
regulation of mitosisGO:0007088630.074
cellular macromolecular complex assemblyGO:00346223240.074
response to biotic stimulusGO:00096072760.074
striated muscle myosin thick filament assemblyGO:007168820.073
ribonucleoside monophosphate catabolic processGO:00091581580.073
posttranscriptional regulation of gene expressionGO:00106082130.071
dna conformation changeGO:00711031130.069
response to alcoholGO:0097305640.066
developmental process involved in reproductionGO:0003006660.065
regulation of gtpase activityGO:00430871800.064
epithelium developmentGO:00604292270.063
single organism membrane organizationGO:00448022680.063
small gtpase mediated signal transductionGO:0007264780.063
meiotic chromosome separationGO:005130730.062
cellular homeostasisGO:00197251960.062
regulation of nuclear divisionGO:0051783650.062
negative regulation of cysteine type endopeptidase activityGO:2000117480.061
g2 dna damage checkpointGO:0031572260.061
histone modificationGO:00165702510.060
negative regulation of cellular protein metabolic processGO:00322693530.060
positive regulation of purine nucleotide metabolic processGO:19005442270.059
stress activated mapk cascadeGO:0051403930.059
protein tetramerizationGO:0051262470.056
negative regulation of kinase activityGO:00336731060.056
autophagic cell deathGO:004810230.056
purine ribonucleoside monophosphate catabolic processGO:00091691580.055
negative regulation of chromosome organizationGO:2001251480.055
regulation of kinase activityGO:00435493140.055
nucleoside monophosphate catabolic processGO:00091251590.054
response to external biotic stimulusGO:00432072610.054
regulation of stress activated protein kinase signaling cascadeGO:0070302850.053
viral life cycleGO:00190581320.053
positive regulation of nucleotide catabolic processGO:00308131850.053
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.053
vesicle mediated transportGO:00161923710.051
defense response to other organismGO:00985421290.051
circulatory system developmentGO:00723592620.051
myosin filament organizationGO:003103320.050
positive regulation of cellular amino acid metabolic processGO:004576430.048
endocytosisGO:00068971590.048
positive regulation of nucleotide metabolic processGO:00459812300.048
cellular chemical homeostasisGO:00550821800.048
regulation of transferase activityGO:00513383550.047
peptidyl serine modificationGO:00182091060.046
regulation of nucleotide catabolic processGO:00308112050.044
establishment of organelle localizationGO:0051656590.044
neuron projection morphogenesisGO:0048812500.043
cofactor biosynthetic processGO:0051188310.043
organelle assemblyGO:00709251760.042
agingGO:0007568660.041
negative regulation of secretion by cellGO:1903531520.041
regulation of cell divisionGO:00513021160.041
negative regulation of endopeptidase activityGO:0010951840.041
neuron differentiationGO:00301821380.039
regulation of cell activationGO:00508651250.039
immune system developmentGO:00025201950.037
signal transduction by phosphorylationGO:00230142970.036
cell agingGO:0007569520.036
dna packagingGO:0006323770.035
blood vessel developmentGO:00015681720.035
response to hypoxiaGO:0001666960.035
regulation of protein acetylationGO:1901983250.033
fatty acid metabolic processGO:00066311150.033
gtp catabolic processGO:00061842370.033
mismatch repairGO:0006298150.033
protein oligomerizationGO:00512591730.032
regulation of nucleotide metabolic processGO:00061402690.032
hemopoiesisGO:00300971800.032
cell cycle checkpointGO:00000751170.032
mitotic sister chromatid segregationGO:0000070530.032
positive regulation of protein phosphorylationGO:00019343130.032
cellular divalent inorganic cation homeostasisGO:00725031280.031
negative regulation of cellular component organizationGO:00511292350.031
guanosine containing compound metabolic processGO:19010682440.030
cell type specific apoptotic processGO:00972851250.030
cell adhesionGO:00071553250.030
blood vessel morphogenesisGO:00485141620.030
dna duplex unwindingGO:0032508300.029
regulation of chromatin modificationGO:1903308510.029
cardiovascular system developmentGO:00723582620.029
regulation of chromosome segregationGO:0051983440.029
regulation of cytokine productionGO:00018172320.028
regulation of gene expression epigeneticGO:0040029730.028
microtubule cytoskeleton organizationGO:00002261760.028
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.027
maintenance of locationGO:00512351120.027
amine metabolic processGO:0009308440.027
positive regulation of vesicle fusionGO:003134040.027
nucleotide biosynthetic processGO:00091651090.027
sister chromatid segregationGO:0000819540.027
cellular response to hormone stimulusGO:00328701250.026
female gamete generationGO:000729220.026
reproductive structure developmentGO:0048608550.026
osteoclast developmentGO:003603520.026
anatomical structure homeostasisGO:00602491000.025
negative regulation of transferase activityGO:00513481240.025
reproductive processGO:00224141060.025
wnt signaling pathwayGO:00160551560.025
stem cell developmentGO:0048864690.024
multi organism cellular processGO:00447641560.024
generation of neuronsGO:00486991520.024
positive regulation of lymphocyte activationGO:0051251730.023
endomembrane system organizationGO:00102561960.023
meiosis iGO:000712740.023
organophosphate biosynthetic processGO:00904071630.022
regulation of g1 s transition of mitotic cell cycleGO:2000045400.022
regulation of cell growthGO:00015581350.022
regulation of nucleoside metabolic processGO:00091182090.022
reproductive system developmentGO:0061458560.022
negative regulation of response to dna damage stimulusGO:2001021330.022
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.022
neurogenesisGO:00220081690.021
regulation of double strand break repairGO:2000779220.021
atp catabolic processGO:00062001570.021
medium chain fatty acid metabolic processGO:005179140.021
modification dependent macromolecule catabolic processGO:00436322120.021
atp dependent chromatin remodelingGO:0043044250.021
regulation of dna replicationGO:0006275680.020
mitotic cytokinesisGO:0000281190.020
metaphase anaphase transition of mitotic cell cycleGO:0007091210.020
angiogenesisGO:00015251470.020
regulation of protein serine threonine kinase activityGO:00719001790.020
sex differentiationGO:0007548450.020
nuclear transportGO:00511691790.020
chromosome separationGO:0051304230.020
cell cycle g2 m phase transitionGO:0044839430.019
2 deoxyribonucleotide metabolic processGO:000939460.019
chromatin organizationGO:00063253510.019
cellular response to steroid hormone stimulusGO:0071383370.019
cellular response to oxygen containing compoundGO:19017012760.019
negative regulation of nervous system developmentGO:0051961280.019
response to hormoneGO:00097251750.018
protein ubiquitinationGO:00165673140.018
meiotic cell cycleGO:0051321130.018
regulation of peptidase activityGO:00525471800.018
regulation of stress activated mapk cascadeGO:0032872840.018
phagocytosisGO:0006909420.018
double strand break repair via homologous recombinationGO:0000724500.018
positive regulation of endopeptidase activityGO:0010950840.018
lymphocyte activationGO:00466491330.018
positive regulation of cellular component organizationGO:00511303760.018
neuron projection developmentGO:00311751060.018
positive regulation of cell cycle processGO:00900681060.017
cell activationGO:00017752130.017
regulation of purine nucleotide metabolic processGO:19005422640.017
negative regulation of cell cycle processGO:00109481210.017
regulation of purine nucleotide catabolic processGO:00331212050.017
chemical homeostasisGO:00488783060.016
nervous system developmentGO:00073992930.016
cytokine secretionGO:0050663640.016
stress activated protein kinase signaling cascadeGO:0031098940.016
nuclear importGO:00511701060.016
response to extracellular stimulusGO:0009991850.016
regulation of vesicle fusionGO:003133850.015
deoxyribonucleotide metabolic processGO:000926260.015
gtp metabolic processGO:00460392390.015
actomyosin contractile ring organizationGO:004483710.015
protein dna complex subunit organizationGO:0071824800.015
negative regulation of cell proliferationGO:00082852280.015
dephosphorylationGO:00163112090.015
microtubule based processGO:00070172100.015
single organism reproductive processGO:0044702980.015
intracellular transport of virusGO:0075733140.015
response to nutrientGO:0007584200.015
chromatin remodelingGO:0006338550.014
ras protein signal transductionGO:0007265730.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
regulation of immune responseGO:00507762010.014
regulation of wnt signaling pathwayGO:00301111230.014
mitotic nuclear divisionGO:00070671190.014
regulation of cellular amine metabolic processGO:0033238110.014
muscle structure developmentGO:0061061980.014
positive regulation of exit from mitosisGO:003153620.013
mitotic dna damage checkpointGO:0044773280.013
response to organonitrogen compoundGO:00102431560.013
negative regulation of protein phosphorylationGO:00019331400.013
dna unwinding involved in dna replicationGO:000626820.013
interspecies interaction between organismsGO:00444191560.013
regulation of protein catabolic processGO:00421761550.013
mitotic dna integrity checkpointGO:0044774300.013
negative regulation of chromatin modificationGO:1903309210.013
regulation of response to dna damage stimulusGO:2001020940.013
cytokine mediated signaling pathwayGO:00192211090.013
regulation of intrinsic apoptotic signaling pathway in response to dna damageGO:1902229200.013
rna interferenceGO:001624640.013
cellular response to organonitrogen compoundGO:00714171240.012
negative regulation of mapk cascadeGO:0043409560.012
protein targetingGO:00066051870.012
reciprocal dna recombinationGO:003582540.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
regulation of cellular amino acid metabolic processGO:000652160.012
reproductionGO:0000003630.012
regulation of protein bindingGO:0043393660.012
negative regulation of phosphatase activityGO:0010923610.012
protein maturationGO:00516042330.012
negative regulation of protein kinase activityGO:0006469980.011
locomotory behaviorGO:000762610.011
regulation of atp catabolic processGO:1903289250.011
regulation of phosphatase activityGO:0010921810.011
morphogenesis of an epitheliumGO:0002009600.011
positive regulation of chromosome organizationGO:2001252410.011
spindle organizationGO:0007051530.011
response to virusGO:00096151260.011
retina development in camera type eyeGO:0060041150.011
single organism cellular localizationGO:19025803320.011
cell projection organizationGO:00300302520.011
positive regulation of cell cycleGO:00457871400.011
posttranscriptional gene silencingGO:0016441250.011
meiotic chromosome segregationGO:004513240.011
regulation of mitotic sister chromatid segregationGO:0033047270.011
negative regulation of protein complex assemblyGO:0031333430.011
negative regulation of bindingGO:0051100570.011
mesenchymal cell differentiationGO:0048762520.010
skeletal myofibril assemblyGO:001486630.010
negative regulation of catabolic processGO:00098951040.010
cell part morphogenesisGO:00329901370.010
macromolecule methylationGO:0043414970.010

TK1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:3311860.166
neurodegenerative diseaseDOID:12891020.166
nervous system diseaseDOID:8634310.166