Homo sapiens

0 known processes

CSMD1

CUB and Sushi multiple domains 1

(Aliases: KIAA1890)

CSMD1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.080
cellular ketone metabolic processGO:0042180800.079
regulation of cellular ketone metabolic processGO:0010565500.065
inorganic ion transmembrane transportGO:00986602310.063
ion transmembrane transportGO:00342203380.063
regulation of cellular amine metabolic processGO:0033238110.063
transmembrane transportGO:00550853990.063
cellular amino acid metabolic processGO:00065201160.063
locomotory behaviorGO:000762610.061
regulation of cellular amino acid metabolic processGO:000652160.056
cellular amine metabolic processGO:0044106410.052
cation transmembrane transportGO:00986552380.050
amine metabolic processGO:0009308440.049
ras protein signal transductionGO:0007265730.049
inorganic cation transmembrane transportGO:00986621940.049
nervous system developmentGO:00073992930.047
small gtpase mediated signal transductionGO:0007264780.044
purine ribonucleoside metabolic processGO:00461284370.043
positive regulation of cellular amino acid metabolic processGO:004576430.041
regulation of cellular component movementGO:00512703340.041
cation transportGO:00068123310.041
metal ion transportGO:00300012720.041
regulation of locomotionGO:00400123290.040
cytoplasmic transportGO:00164823790.039
multicellular organismal agingGO:001025930.038
positive regulation of cellular amine metabolic processGO:003324070.038
cellular component morphogenesisGO:00329893140.038
positive regulation of cellular component organizationGO:00511303760.037
female gamete generationGO:000729220.037
cell morphogenesisGO:00009022960.036
ribonucleoside triphosphate metabolic processGO:00091994120.036
purine nucleotide catabolic processGO:00061954050.036
positive regulation of transportGO:00510503360.036
hindbrain developmentGO:003090230.036
negative regulation of protein metabolic processGO:00512483910.035
Human
organophosphate catabolic processGO:00464344300.035
cell developmentGO:00484683280.035
ribonucleotide catabolic processGO:00092614050.035
oogenesisGO:004847720.034
nucleoside triphosphate metabolic processGO:00091414220.034
glycosyl compound catabolic processGO:19016584130.034
cellular response to endogenous stimulusGO:00714953360.034
negative regulation of multicellular organismal processGO:00512413170.033
nitrogen compound transportGO:00717051910.033
purine nucleoside catabolic processGO:00061523980.033
purine containing compound catabolic processGO:00725234110.033
generation of neuronsGO:00486991520.032
purine ribonucleoside triphosphate catabolic processGO:00092073910.032
regulation of hormone levelsGO:00108171250.032
determination of adult lifespanGO:000834020.032
purine ribonucleoside triphosphate metabolic processGO:00092054110.032
purine nucleoside triphosphate metabolic processGO:00091444120.032
nucleoside triphosphate catabolic processGO:00091433940.032
regulation of nucleotide metabolic processGO:00061402690.031
ribonucleoside triphosphate catabolic processGO:00092033910.031
purine ribonucleotide catabolic processGO:00091544040.031
regulation of membrane potentialGO:0042391950.031
lipid metabolic processGO:00066293810.031
chemical homeostasisGO:00488783060.031
Mouse
ribonucleoside catabolic processGO:00424544060.031
negative regulation of catalytic activityGO:00430863350.031
Human
secretion by cellGO:00329402260.030
negative regulation of phosphorus metabolic processGO:00105632670.030
single organism cellular localizationGO:19025803320.030
positive regulation of phosphorylationGO:00423273940.030
purine ribonucleoside catabolic processGO:00461303980.030
nucleotide catabolic processGO:00091664080.029
negative regulation of cellular protein metabolic processGO:00322693530.029
Human
system processGO:00030083490.029
Mouse
cellular lipid metabolic processGO:00442553030.029
segmentationGO:003528240.029
metencephalon developmentGO:002203720.029
nerve developmentGO:002167540.029
regulation of purine nucleotide metabolic processGO:19005422640.029
nucleoside catabolic processGO:00091644080.028
nucleoside phosphate catabolic processGO:19012924120.028
regulation of anatomical structure morphogenesisGO:00226032860.028
negative regulation of phosphate metabolic processGO:00459362670.028
positive regulation of catabolic processGO:00098963100.028
purine nucleoside triphosphate catabolic processGO:00091463920.028
cranial nerve developmentGO:002154540.028
muscle system processGO:0003012810.027
organonitrogen compound biosynthetic processGO:19015662000.027
response to abiotic stimulusGO:00096283360.027
single organism membrane organizationGO:00448022680.027
positive regulation of cellular catabolic processGO:00313312840.027
anatomical structure formation involved in morphogenesisGO:00486462840.027
secretionGO:00469032540.027
matingGO:000761810.026
peripheral nervous system developmentGO:000742220.026
monovalent inorganic cation transportGO:00156721280.026
adult locomotory behaviorGO:000834410.026
regulation of secretionGO:00510461940.026
regulation of transferase activityGO:00513383550.026
actin filament based processGO:00300292240.026
positive regulation of cell proliferationGO:00082843010.026
cell fate determinationGO:000170930.026
biological adhesionGO:00226103310.026
startle responseGO:000196430.026
Mouse
cardiac muscle cell contractionGO:008600340.026
cell projection organizationGO:00300302520.025
regulation of cell cycleGO:00517263930.025
guanosine containing compound catabolic processGO:19010692390.025
cation homeostasisGO:00550801890.025
regulation of cellular response to stressGO:00801352440.025
regulation of nucleoside metabolic processGO:00091182090.025
regulation of kinase activityGO:00435493140.025
neurological system processGO:00508771630.024
Mouse
signal transduction by phosphorylationGO:00230142970.024
regulation of cell motilityGO:20001452990.024
cell adhesionGO:00071553250.024
negative regulation of apoptotic processGO:00430663160.024
mitotic cell cycleGO:00002783260.024
regulation of protein localizationGO:00328802960.024
regulation of ras protein signal transductionGO:00465781550.024
neuromuscular junction developmentGO:000752830.024
cellular response to dna damage stimulusGO:00069743790.024
forebrain generation of neuronsGO:002187230.024
protein catabolic processGO:00301633250.024
response to oxygen containing compoundGO:19017003690.024
guanosine containing compound metabolic processGO:19010682440.023
neurogenesisGO:00220081690.023
mapk cascadeGO:00001652880.023
positive regulation of transferase activityGO:00513472270.023
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.023
rho protein signal transductionGO:0007266260.023
regulation of ion transmembrane transportGO:00347651320.023
cell cell signalingGO:00072671550.023
regenerationGO:003109940.023
positive regulation of developmental processGO:00510943140.023
carbohydrate derivative biosynthetic processGO:19011372070.023
negative regulation of cell deathGO:00605483450.023
ion homeostasisGO:00508012300.022
cellular potassium ion transportGO:0071804600.022
protein localization to organelleGO:00333652800.022
negative regulation of intracellular signal transductionGO:19025321830.022
positive regulation of hydrolase activityGO:00513453310.022
Human
neuron differentiationGO:00301821380.022
regulation of secretion by cellGO:19035301770.022
cerebellum developmentGO:002154920.022
associative learningGO:000830610.022
inner ear morphogenesisGO:004247240.021
regulation of transmembrane transportGO:00347621390.021
regulation of synaptic plasticityGO:004816730.021
gtp metabolic processGO:00460392390.021
regulation of cytokine productionGO:00018172320.021
regulation of cell differentiationGO:00455953930.021
metal ion homeostasisGO:00550651690.021
positive regulation of purine nucleotide metabolic processGO:19005442270.021
negative regulation of protein modification processGO:00314002000.021
positive regulation of protein phosphorylationGO:00019343130.020
defense responseGO:00069523150.020
Human
actin filament based movementGO:0030048170.020
positive regulation of nucleotide metabolic processGO:00459812300.020
regulation of mapk cascadeGO:00434082620.020
organ formationGO:004864530.020
membrane organizationGO:00610242920.020
negative regulation of phosphorylationGO:00423261740.020
cellular protein catabolic processGO:00442572610.020
muscle contractionGO:0006936730.019
sensory perception of painGO:001923340.019
negative regulation of cell proliferationGO:00082852280.019
calcium ion homeostasisGO:00550741220.019
cellular macromolecule catabolic processGO:00442653800.019
organophosphate biosynthetic processGO:00904071630.019
regulation of gtpase activityGO:00430871800.019
gtp catabolic processGO:00061842370.019
positive regulation of organelle organizationGO:00106381950.019
immune responseGO:00069553070.019
Human
blastoderm segmentationGO:000735020.019
limbic system developmentGO:002176130.019
regulation of cellular component biogenesisGO:00440872810.019
mitotic cell cycle processGO:19030472860.019
divalent inorganic cation transportGO:00725111580.019
regulation of cell cycle processGO:00105642660.019
oocyte differentiationGO:000999420.019
calcium ion transportGO:00068161470.019
sensory perceptionGO:00076001030.019
oocyte developmentGO:004859910.019
regulation of protein kinase activityGO:00458592890.019
protein ubiquitinationGO:00165673140.019
circadian behaviorGO:004851220.018
rhythmic behaviorGO:000762220.018
cytokine productionGO:00018162470.018
memoryGO:000761330.018
detection of stimulusGO:0051606850.018
negative regulation of cellular component organizationGO:00511292350.018
morphogenesis of embryonic epitheliumGO:001633140.018
negative regulation of programmed cell deathGO:00430693210.018
regulation of ion transportGO:00432691890.018
regulation of purine nucleotide catabolic processGO:00331212050.018
photoreceptor cell differentiationGO:004653020.018
intracellular protein transportGO:00068862700.018
regulation of gtp catabolic processGO:00331241800.018
chromatin modificationGO:00165682980.018
regulation of protein transportGO:00512232130.018
growthGO:00400072020.018
chromatin organizationGO:00063253510.018
enzyme linked receptor protein signaling pathwayGO:00071673030.018
positive regulation of kinase activityGO:00336742040.018
protein modification by small protein conjugationGO:00324463420.017
positive regulation of cell differentiationGO:00455972110.017
dephosphorylationGO:00163112090.017
purine nucleotide biosynthetic processGO:0006164840.017
multicellular organismal response to stressGO:003355510.017
microtubule based processGO:00070172100.017
membrane hyperpolarizationGO:006008110.017
regulation of small gtpase mediated signal transductionGO:00510561560.017
regulation of proteolysisGO:00301622930.017
Human
cell growthGO:00160491600.017
central nervous system developmentGO:00074171230.017
positive regulation of synaptic transmissionGO:005080640.017
regulation of cell migrationGO:00303342890.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
positive regulation of nucleotide catabolic processGO:00308131850.017
reactive oxygen species biosynthetic processGO:190340940.017
positive regulation of nucleoside metabolic processGO:00459791860.017
actin mediated cell contractionGO:0070252120.017
establishment of protein localization to organelleGO:00725941720.017
organ morphogenesisGO:00098871470.017
neurotransmitter secretionGO:000726940.017
lipid biosynthetic processGO:00086101770.017
spermatid differentiationGO:004851540.017
purine containing compound biosynthetic processGO:0072522880.017
cell morphogenesis involved in differentiationGO:00009041440.016
negative regulation of cell cycleGO:00457861930.016
actin cytoskeleton organizationGO:00300362070.016
cellular cation homeostasisGO:00300031630.016
regulation of nucleotide catabolic processGO:00308112050.016
positive regulation of gtp catabolic processGO:00331261660.016
potassium ion transportGO:0006813620.016
positive regulation of cellular component movementGO:00512721810.016
regulation of establishment of protein localizationGO:00702012420.016
regulation of response to external stimulusGO:00321012220.016
Human
positive regulation of gtpase activityGO:00435471660.016
protein targetingGO:00066051870.016
neuron projection developmentGO:00311751060.016
anterior posterior axis specificationGO:000994820.016
regulation of neural precursor cell proliferationGO:200017740.016
histone modificationGO:00165702510.016
nucleocytoplasmic transportGO:00069131760.016
potassium ion transmembrane transportGO:0071805600.016
negative regulation of developmental processGO:00510932470.016
nucleotide biosynthetic processGO:00091651090.016
regulation of cell developmentGO:00602841610.016
anion transportGO:00068201610.016
head developmentGO:00603221080.016
nucleoside phosphate biosynthetic processGO:19012931090.016
regulation of ras gtpase activityGO:00323181280.016
cellular macromolecular complex assemblyGO:00346223240.016
small molecule biosynthetic processGO:00442831570.016
regulation of growthGO:00400081650.016
forelimb morphogenesisGO:003513640.015
positive regulation of monocyte chemotactic protein 1 productionGO:007163930.015
sex determinationGO:000753030.015
negative regulation of hydrolase activityGO:00513461820.015
Human
cell projection morphogenesisGO:00488581290.015
compound eye developmentGO:004874910.015
forebrain neuron differentiationGO:002187930.015
small molecule catabolic processGO:0044282920.015
regulation of cell growthGO:00015581350.015
neuron fate commitmentGO:004866320.015
posttranscriptional regulation of gene expressionGO:00106082130.015
protein maturationGO:00516042330.015
Human
motor neuron axon guidanceGO:000804520.015
regulation of neuron differentiationGO:0045664700.015
carbohydrate metabolic processGO:00059752070.015
cell part morphogenesisGO:00329901370.015
vesicle mediated transportGO:00161923710.015
rna processingGO:00063962550.015
endomembrane system organizationGO:00102561960.015
embryonic epithelial tube formationGO:000183840.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
positive regulation of purine nucleotide catabolic processGO:00331231850.015
dna repairGO:00062811980.015
negative regulation of cellular amine metabolic processGO:003323930.015
positive regulation of protein kinase activityGO:00458601900.015
covalent chromatin modificationGO:00165692540.015
cellular homeostasisGO:00197251960.015
apoptotic signaling pathwayGO:00971902680.015
regulation of cell morphogenesisGO:00226041530.015
maintenance of locationGO:00512351120.015
positive regulation of cellular component biogenesisGO:00440891580.015
positive regulation of secretionGO:00510471160.015
regulation of mitotic cell cycleGO:00073461890.015
regulation of meiotic cell cycleGO:005144540.014
specification of organ identityGO:001009230.014
cellular response to oxygen containing compoundGO:19017012760.014
monocarboxylic acid metabolic processGO:00327871850.014
wnt signaling pathwayGO:00160551560.014
divalent inorganic cation homeostasisGO:00725071360.014
cardiac right ventricle morphogenesisGO:000321530.014
nuclear transportGO:00511691790.014
cell projection assemblyGO:00300311260.014
cardiovascular system developmentGO:00723582620.014
ribonucleotide biosynthetic processGO:0009260810.014
positive regulation of mapk cascadeGO:00434101900.014
somitogenesisGO:000175620.014
embryonic camera type eye developmentGO:003107620.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
positive regulation of secretion by cellGO:19035321080.014
divalent metal ion transportGO:00708381520.014
positive regulation of protein transportGO:00512221350.014
positive regulation of apoptotic processGO:00430652460.014
sleepGO:003043120.014
spermatid developmentGO:000728640.014
brain developmentGO:0007420970.014
positive regulation of cell motilityGO:20001471770.014
regulation of endopeptidase activityGO:00525481700.014
Human
cell cycle phase transitionGO:00447701730.014
protein oligomerizationGO:00512591730.014
positive regulation of immune system processGO:00026842830.014
Human
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
regulation of peptidase activityGO:00525471800.014
Human
circulatory system developmentGO:00723592620.014
neuron developmentGO:00486661130.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
visual behaviorGO:000763220.014
regulation of metal ion transportGO:00109591200.014
cellular response to growth factor stimulusGO:00713631970.014
protein localization to membraneGO:00726571600.014
innate immune responseGO:00450871780.014
Human
response to fungusGO:000962040.013
reactive nitrogen species metabolic processGO:200105730.013
cell divisionGO:00513011680.013
positive regulation of cytokine productionGO:00018191670.013
positive regulation of programmed cell deathGO:00430682490.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
glial cell migrationGO:000834740.013
nucleoside monophosphate metabolic processGO:00091231910.013
regulation of cell projection organizationGO:00313441070.013
negative regulation of cell motilityGO:20001461040.013
microtubule cytoskeleton organizationGO:00002261760.013
amide transportGO:0042886760.013
single organism carbohydrate metabolic processGO:00447231930.013
glycoprotein metabolic processGO:00091001100.013
anterior posterior axis specification embryoGO:000859520.013
negative regulation of organelle organizationGO:00106391260.013
positive regulation of ras gtpase activityGO:00323201170.013
atp metabolic processGO:00460341760.013
epithelium developmentGO:00604292270.013
syncytium formation by plasma membrane fusionGO:000076820.013
oxidation reduction processGO:00551143960.013
negative regulation of cellular component movementGO:00512711060.013
regulation of atrial cardiac muscle cell membrane repolarizationGO:006037240.013
spinal cord developmentGO:002151040.013
response to radiationGO:00093141510.013
tripartite regional subdivisionGO:000735120.013
negative regulation of protein phosphorylationGO:00019331400.013
cellular chemical homeostasisGO:00550821800.013
cellular calcium ion homeostasisGO:00068741170.013
regulation of protein processingGO:00706131500.013
Human
hormone secretionGO:0046879650.013
positive regulation of locomotionGO:00400171860.013
hemopoiesisGO:00300971800.013
Human
regulation of dna metabolic processGO:00510521530.013
ubiquitin dependent protein catabolic processGO:00065112060.013
proteasomal protein catabolic processGO:00104981760.013
modification dependent macromolecule catabolic processGO:00436322120.013
negative regulation of transportGO:00510511760.013
positive regulation of cell cycleGO:00457871400.013
response to nitrogen compoundGO:19016981840.013
aortic valve developmentGO:000317630.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
regulation of cell adhesionGO:00301551660.012
action potentialGO:0001508340.012
regulation of intracellular transportGO:00323861950.012
positive regulation of neural precursor cell proliferationGO:200017920.012
mitotic cell cycle phase transitionGO:00447721620.012
visual learningGO:000854210.012
tissue regenerationGO:004224630.012
cellular response to cytokine stimulusGO:00713451810.012
single organism cell adhesionGO:00986021790.012
neuroblast proliferationGO:000740540.012
modification dependent protein catabolic processGO:00199412090.012
immune system developmentGO:00025201950.012
Human
protein autophosphorylationGO:00467771230.012
regulation of cytoskeleton organizationGO:00514931770.012
organelle assemblyGO:00709251760.012
cyclic purine nucleotide metabolic processGO:0052652600.012
forebrain regionalizationGO:002187130.012
protein acylationGO:00435431380.012
protein processingGO:00164852260.012
Human
hormone transportGO:0009914680.012
organic hydroxy compound metabolic processGO:19016151470.012
blastocyst developmentGO:000182430.012
positive regulation of tooth mineralizationGO:007017220.012
regulation of nervous system developmentGO:0051960880.012
signal releaseGO:0023061700.012
regulation of neurogenesisGO:0050767820.012
regulation of protein complex assemblyGO:00432541470.012
cell activationGO:00017752130.012
Human
fatty acid metabolic processGO:00066311150.012
multicellular organismal signalingGO:0035637340.012
cellular divalent inorganic cation homeostasisGO:00725031280.012
blood vessel developmentGO:00015681720.012
positive regulation of cell deathGO:00109422630.012
purine ribonucleotide biosynthetic processGO:0009152790.012
protein localization to nucleusGO:00345041360.012
regulation of multi organism processGO:00439001570.012
response to organonitrogen compoundGO:00102431560.012
negative regulation of protein processingGO:00109551420.012
Human
pituitary gland developmentGO:002198320.012
regulation of protein catabolic processGO:00421761550.012
epithelial cell differentiationGO:00308551410.012
eye photoreceptor cell differentiationGO:000175420.012
negative regulation of cell migrationGO:00303361020.012
peptidyl tyrosine phosphorylationGO:00181081700.012
regulation of apoptotic signaling pathwayGO:20012331750.012
striated muscle contractionGO:0006941520.012
regulation of excitatory postsynaptic membrane potentialGO:006007910.012
cell substrate adhesionGO:00315891320.012
meiosis iGO:000712740.012
release of cytoplasmic sequestered nf kappabGO:000858840.011
g protein coupled receptor signaling pathwayGO:00071862070.011
regulation of protein maturationGO:19033171500.011
Human
response to external biotic stimulusGO:00432072610.011
regulation of axon guidanceGO:190266730.011
cardiac muscle contractionGO:0060048340.011
negative regulation of locomotionGO:00400131180.011
peptidyl tyrosine modificationGO:00182121700.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
nucleoside monophosphate catabolic processGO:00091251590.011
cerebral cortex cell migrationGO:002179530.011
tube closureGO:006060630.011
cellular protein complex assemblyGO:00436231880.011
cellular ion homeostasisGO:00068731680.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
Human
response to growth factorGO:00708482050.011
response to axon injuryGO:004867810.011
positive regulation of ion transportGO:0043270870.011
reproductive processGO:00224141060.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
response to biotic stimulusGO:00096072760.011
regulation of homeostatic processGO:00328441210.011
regulation of wnt signaling pathwayGO:00301111230.011
myoblast fusionGO:000752010.011
neural tube formationGO:000184130.011
positive regulation of cell developmentGO:0010720920.011
i kappab kinase nf kappab signalingGO:00072491660.011
regulation of actin filament based processGO:00329701410.011
regulation of chromosome organizationGO:00330441030.011
cellular metal ion homeostasisGO:00068751460.011
response to hypoxiaGO:0001666960.011
regulation of postsynaptic membrane potentialGO:006007810.011
sequestering of metal ionGO:0051238240.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
ribose phosphate biosynthetic processGO:0046390820.011
hippocampus developmentGO:002176610.011
regulation of protein serine threonine kinase activityGO:00719001790.011
cyclic nucleotide biosynthetic processGO:0009190610.011
thymus developmentGO:004853830.011
positive regulation of cell cycle processGO:00900681060.011
negative regulation of growthGO:0045926970.011
regulation of cytoplasmic transportGO:19036491490.011
purine nucleoside monophosphate catabolic processGO:00091281580.011
carboxylic acid biosynthetic processGO:0046394970.011
optic nerve developmentGO:002155420.011
cellular response to hormone stimulusGO:00328701250.011
negative regulation of phosphatidylinositol 3 kinase signalingGO:001406740.011
response to oxygen levelsGO:00704821000.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
response to other organismGO:00517072610.011
rna splicingGO:00083801310.011
cyclic nucleotide metabolic processGO:0009187820.011
behaviorGO:00076101120.011
negative regulation of synaptic transmissionGO:005080520.011
somatic muscle developmentGO:000752510.011
regulation of bindingGO:00510981110.011
response to decreased oxygen levelsGO:0036293960.011
negative regulation of proteolysisGO:00458611320.011
Human
glycoprotein biosynthetic processGO:0009101910.011
positive regulation of cell migrationGO:00303351720.011
negative regulation of transferase activityGO:00513481240.011
positive regulation of proteolysisGO:00458621420.010
Human
regulation of cell divisionGO:00513021160.010
translationGO:00064121320.010
mitochondrion organizationGO:00070051560.010

CSMD1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.028
nervous system diseaseDOID:8634310.028
disease of metabolismDOID:00146672950.019
eye and adnexa diseaseDOID:14921500.017
eye diseaseDOID:56141490.016
musculoskeletal system diseaseDOID:172230.016
Human
central nervous system diseaseDOID:3311860.015
disease of cellular proliferationDOID:145661740.014
cancerDOID:1621670.014
organ system cancerDOID:00506861640.014
inherited metabolic disorderDOID:6552420.012
cardiovascular system diseaseDOID:12871060.012
retinal diseaseDOID:56791180.012
retinal degenerationDOID:8466890.012
auditory system diseaseDOID:2742530.012