Homo sapiens

17 known processes

HMGCLL1

3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1

(Aliases: bA418P12.1,DKFZp434G1411)

HMGCLL1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.069
cellular amino acid metabolic processGO:00065201160.066
cellular amine metabolic processGO:0044106410.065
amine metabolic processGO:0009308440.064
cellular ketone metabolic processGO:0042180800.063
regulation of cellular amino acid metabolic processGO:000652160.055
regulation of cellular amine metabolic processGO:0033238110.055
regulation of cellular ketone metabolic processGO:0010565500.052
locomotory behaviorGO:000762610.052
positive regulation of cellular amine metabolic processGO:003324070.051
positive regulation of cellular amino acid metabolic processGO:004576430.050
system processGO:00030083490.040
female gamete generationGO:000729220.039
lipid metabolic processGO:00066293810.038
multicellular organismal agingGO:001025930.038
ras protein signal transductionGO:0007265730.037
organophosphate catabolic processGO:00464344300.036
purine ribonucleoside metabolic processGO:00461284370.036
biological adhesionGO:00226103310.036
positive regulation of phosphorylationGO:00423273940.035
cell adhesionGO:00071553250.035
oogenesisGO:004847720.035
determination of adult lifespanGO:000834020.035
small gtpase mediated signal transductionGO:0007264780.034
positive regulation of hydrolase activityGO:00513453310.033
nucleoside catabolic processGO:00091644080.032
purine containing compound catabolic processGO:00725234110.032
nucleoside phosphate catabolic processGO:19012924120.031
negative regulation of protein metabolic processGO:00512483910.031
ribonucleoside triphosphate catabolic processGO:00092033910.031
nucleoside triphosphate metabolic processGO:00091414220.031
ribonucleoside triphosphate metabolic processGO:00091994120.031
ribonucleoside catabolic processGO:00424544060.031
cellular lipid metabolic processGO:00442553030.031
nucleoside triphosphate catabolic processGO:00091433940.031
purine ribonucleotide catabolic processGO:00091544040.030
purine nucleoside triphosphate metabolic processGO:00091444120.030
purine ribonucleoside catabolic processGO:00461303980.030
glycosyl compound catabolic processGO:19016584130.030
actin filament based processGO:00300292240.030
nervous system developmentGO:00073992930.030
purine nucleoside triphosphate catabolic processGO:00091463920.030
nucleotide catabolic processGO:00091664080.029
negative regulation of phosphate metabolic processGO:00459362670.029
purine ribonucleoside triphosphate catabolic processGO:00092073910.029
negative regulation of catalytic activityGO:00430863350.029
mapk cascadeGO:00001652880.029
ribonucleotide catabolic processGO:00092614050.029
negative regulation of phosphorus metabolic processGO:00105632670.028
negative regulation of cellular protein metabolic processGO:00322693530.028
positive regulation of transportGO:00510503360.028
purine nucleotide catabolic processGO:00061954050.028
transmembrane transportGO:00550853990.028
rho protein signal transductionGO:0007266260.028
positive regulation of catabolic processGO:00098963100.028
purine nucleoside catabolic processGO:00061523980.027
ion transmembrane transportGO:00342203380.027
signal transduction by phosphorylationGO:00230142970.027
immune responseGO:00069553070.027
cytoplasmic transportGO:00164823790.027
purine ribonucleoside triphosphate metabolic processGO:00092054110.027
positive regulation of cellular component organizationGO:00511303760.027
segmentationGO:003528240.027
cation transportGO:00068123310.027
regulation of cellular component movementGO:00512703340.027
regulation of protein localizationGO:00328802960.027
single organism cellular localizationGO:19025803320.026
regulation of transferase activityGO:00513383550.026
metal ion transportGO:00300012720.026
response to oxygen containing compoundGO:19017003690.026
vesicle mediated transportGO:00161923710.026
regulation of kinase activityGO:00435493140.025
regenerationGO:003109940.025
positive regulation of cellular catabolic processGO:00313312840.025
cellular macromolecule catabolic processGO:00442653800.025
regulation of purine nucleotide metabolic processGO:19005422640.025
neuromuscular junction developmentGO:000752830.025
chemical homeostasisGO:00488783060.025
memoryGO:000761330.024
cell morphogenesisGO:00009022960.024
regulation of establishment of protein localizationGO:00702012420.024
regulation of protein kinase activityGO:00458592890.024
regulation of mapk cascadeGO:00434082620.024
positive regulation of protein phosphorylationGO:00019343130.024
cellular component morphogenesisGO:00329893140.024
regulation of nucleotide metabolic processGO:00061402690.024
regulation of cellular response to stressGO:00801352440.023
regulation of secretionGO:00510461940.023
defense responseGO:00069523150.023
regulation of cellular component biogenesisGO:00440872810.023
regulation of cell cycleGO:00517263930.023
single organism membrane organizationGO:00448022680.023
cell projection organizationGO:00300302520.023
negative regulation of cell deathGO:00605483450.023
secretionGO:00469032540.022
regulation of locomotionGO:00400123290.022
negative regulation of cellular component organizationGO:00511292350.022
guanosine containing compound catabolic processGO:19010692390.022
dephosphorylationGO:00163112090.022
apoptotic signaling pathwayGO:00971902680.022
gtp catabolic processGO:00061842370.022
regulation of cell differentiationGO:00455953930.022
membrane organizationGO:00610242920.022
enzyme linked receptor protein signaling pathwayGO:00071673030.022
inorganic ion transmembrane transportGO:00986602310.021
negative regulation of programmed cell deathGO:00430693210.021
cellular macromolecular complex assemblyGO:00346223240.021
ion homeostasisGO:00508012300.021
carbohydrate derivative biosynthetic processGO:19011372070.021
response to abiotic stimulusGO:00096283360.021
protein localization to organelleGO:00333652800.021
cellular response to endogenous stimulusGO:00714953360.021
negative regulation of transportGO:00510511760.021
regulation of protein transportGO:00512232130.021
positive regulation of developmental processGO:00510943140.021
positive regulation of cell proliferationGO:00082843010.021
regulation of cell motilityGO:20001452990.021
secretion by cellGO:00329402260.021
carbohydrate metabolic processGO:00059752070.021
inorganic cation transmembrane transportGO:00986621940.021
positive regulation of nucleotide metabolic processGO:00459812300.021
mitotic cell cycleGO:00002783260.021
positive regulation of synaptic transmissionGO:005080640.021
negative regulation of multicellular organismal processGO:00512413170.021
small molecule biosynthetic processGO:00442831570.020
regulation of proteolysisGO:00301622930.020
regulation of cytokine productionGO:00018172320.020
regulation of cell migrationGO:00303342890.020
regulation of secretion by cellGO:19035301770.020
protein catabolic processGO:00301633250.020
organonitrogen compound biosynthetic processGO:19015662000.020
neurological system processGO:00508771630.020
anterior posterior axis specificationGO:000994820.020
negative regulation of apoptotic processGO:00430663160.020
regulation of response to external stimulusGO:00321012220.020
intracellular protein transportGO:00068862700.020
nitrogen compound transportGO:00717051910.020
cellular response to dna damage stimulusGO:00069743790.020
positive regulation of nucleotide catabolic processGO:00308131850.020
guanosine containing compound metabolic processGO:19010682440.020
adult locomotory behaviorGO:000834410.020
positive regulation of mapk cascadeGO:00434101900.019
negative regulation of cell proliferationGO:00082852280.019
single organism cell adhesionGO:00986021790.019
regulation of anatomical structure morphogenesisGO:00226032860.019
gtp metabolic processGO:00460392390.019
regulation of purine nucleotide catabolic processGO:00331212050.019
lipid biosynthetic processGO:00086101770.019
blastoderm segmentationGO:000735020.019
positive regulation of apoptotic processGO:00430652460.019
neurotransmitter secretionGO:000726940.019
cardiac muscle cell contractionGO:008600340.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
innate immune responseGO:00450871780.019
negative regulation of intracellular signal transductionGO:19025321830.019
negative regulation of protein modification processGO:00314002000.019
cellular protein catabolic processGO:00442572610.019
oocyte differentiationGO:000999420.018
single organism carbohydrate metabolic processGO:00447231930.018
positive regulation of purine nucleotide metabolic processGO:19005442270.018
positive regulation of gtp catabolic processGO:00331261660.018
positive regulation of nucleoside metabolic processGO:00459791860.018
positive regulation of immune system processGO:00026842830.018
spermatid differentiationGO:004851540.018
regulation of synaptic plasticityGO:004816730.018
peripheral nervous system developmentGO:000742220.018
regulation of cell adhesionGO:00301551660.018
regulation of nucleoside metabolic processGO:00091182090.018
oocyte developmentGO:004859910.018
cellular homeostasisGO:00197251960.018
mitotic cell cycle processGO:19030472860.018
regulation of cell cycle processGO:00105642660.018
morphogenesis of embryonic epitheliumGO:001633140.018
cellular response to oxygen containing compoundGO:19017012760.018
cytokine productionGO:00018162470.018
proteolysis involved in cellular protein catabolic processGO:00516032440.018
regulation of intracellular transportGO:00323861950.018
negative regulation of cellular amine metabolic processGO:003323930.018
positive regulation of cell deathGO:00109422630.018
cation transmembrane transportGO:00986552380.018
maintenance of locationGO:00512351120.018
negative regulation of hydrolase activityGO:00513461820.018
regulation of nucleotide catabolic processGO:00308112050.018
cell developmentGO:00484683280.018
associative learningGO:000830610.018
protein maturationGO:00516042330.017
rhythmic behaviorGO:000762220.017
hindbrain developmentGO:003090230.017
g protein coupled receptor signaling pathwayGO:00071862070.017
regulation of cytoskeleton organizationGO:00514931770.017
cell growthGO:00160491600.017
response to external biotic stimulusGO:00432072610.017
negative regulation of phosphorylationGO:00423261740.017
reactive oxygen species biosynthetic processGO:190340940.017
organic hydroxy compound metabolic processGO:19016151470.017
positive regulation of organelle organizationGO:00106381950.017
positive regulation of programmed cell deathGO:00430682490.017
protein modification by small protein conjugationGO:00324463420.017
metencephalon developmentGO:002203720.017
reactive nitrogen species metabolic processGO:200105730.017
circadian behaviorGO:004851220.017
response to organic cyclic compoundGO:00140702040.017
monocarboxylic acid metabolic processGO:00327871850.016
matingGO:000761810.016
positive regulation of gtpase activityGO:00435471660.016
microtubule based processGO:00070172100.016
protein ubiquitinationGO:00165673140.016
regulation of reactive oxygen species biosynthetic processGO:190342630.016
positive regulation of transferase activityGO:00513472270.016
cellular chemical homeostasisGO:00550821800.016
endomembrane system organizationGO:00102561960.016
oxidation reduction processGO:00551143960.016
response to lipidGO:00339932060.016
spermatid developmentGO:000728640.016
actin cytoskeleton organizationGO:00300362070.016
positive regulation of purine nucleotide catabolic processGO:00331231850.016
motor neuron axon guidanceGO:000804520.016
protein targetingGO:00066051870.016
startle responseGO:000196430.016
chromatin organizationGO:00063253510.016
cellular response to growth factor stimulusGO:00713631970.016
response to other organismGO:00517072610.016
organophosphate biosynthetic processGO:00904071630.016
neurogenesisGO:00220081690.016
actin filament based movementGO:0030048170.016
regulation of small gtpase mediated signal transductionGO:00510561560.016
regulation of ras protein signal transductionGO:00465781550.016
actin mediated cell contractionGO:0070252120.016
positive regulation of protein kinase activityGO:00458601900.016
divalent metal ion transportGO:00708381520.016
protein localization to membraneGO:00726571600.015
protein processingGO:00164852260.015
positive regulation of kinase activityGO:00336742040.015
response to biotic stimulusGO:00096072760.015
compound eye developmentGO:004874910.015
growthGO:00400072020.015
regulation of gtpase activityGO:00430871800.015
reactive oxygen species metabolic processGO:0072593750.015
cellular protein complex assemblyGO:00436231880.015
regulation of gtp catabolic processGO:00331241800.015
regulation of sequence specific dna binding transcription factor activityGO:00510902110.015
epithelium developmentGO:00604292270.015
negative regulation of developmental processGO:00510932470.015
tripartite regional subdivisionGO:000735120.015
response to growth factorGO:00708482050.015
anatomical structure formation involved in morphogenesisGO:00486462840.015
single organismal cell cell adhesionGO:00163371480.015
negative regulation of cell cycleGO:00457861930.015
regulation of growthGO:00400081650.015
cellular metal ion homeostasisGO:00068751460.015
proteasomal protein catabolic processGO:00104981760.015
anion transportGO:00068201610.015
cerebellum developmentGO:002154920.015
neuroblast proliferationGO:000740540.015
posttranscriptional regulation of gene expressionGO:00106082130.015
nerve developmentGO:002167540.015
limbic system developmentGO:002176130.015
positive regulation of cytokine productionGO:00018191670.014
histone modificationGO:00165702510.014
cell divisionGO:00513011680.014
regulation of cell growthGO:00015581350.014
chromatin modificationGO:00165682980.014
negative regulation of locomotionGO:00400131180.014
regulation of dna metabolic processGO:00510521530.014
modification dependent macromolecule catabolic processGO:00436322120.014
positive regulation of protein transportGO:00512221350.014
response to cytokineGO:00340972320.014
anterior posterior axis specification embryoGO:000859520.014
organic acid biosynthetic processGO:0016053970.014
generation of neuronsGO:00486991520.014
nuclear transportGO:00511691790.014
positive regulation of cellular component biogenesisGO:00440891580.014
regulation of ion transportGO:00432691890.014
syncytium formation by plasma membrane fusionGO:000076820.014
embryonic epithelial tube formationGO:000183840.014
positive regulation of cell differentiationGO:00455972110.014
modification dependent protein catabolic processGO:00199412090.014
organelle assemblyGO:00709251760.014
regulation of immune responseGO:00507762010.014
positive regulation of cellular component movementGO:00512721810.014
tissue regenerationGO:004224630.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
cell part morphogenesisGO:00329901370.014
fatty acid metabolic processGO:00066311150.014
muscle contractionGO:0006936730.014
regulation of membrane potentialGO:0042391950.014
nucleocytoplasmic transportGO:00069131760.014
regulation of cytoplasmic transportGO:19036491490.014
ubiquitin dependent protein catabolic processGO:00065112060.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
regulation of vesicle mediated transportGO:00606271300.014
positive regulation of ras gtpase activityGO:00323201170.013
rna processingGO:00063962550.013
negative regulation of protein phosphorylationGO:00019331400.013
circulatory system developmentGO:00723592620.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
regulation of mitotic cell cycleGO:00073461890.013
positive regulation of secretionGO:00510471160.013
stem cell divisionGO:001714520.013
response to fungusGO:000962040.013
cellular cation homeostasisGO:00300031630.013
nucleoside monophosphate metabolic processGO:00091231910.013
divalent inorganic cation transportGO:00725111580.013
response to hormoneGO:00097251750.013
regulation of cell developmentGO:00602841610.013
regulation of endopeptidase activityGO:00525481700.013
cardiovascular system developmentGO:00723582620.013
regulation of actin filament based processGO:00329701410.013
metal ion homeostasisGO:00550651690.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.013
regulation of peptidase activityGO:00525471800.013
cardiac muscle contractionGO:0060048340.013
regulation of protein serine threonine kinase activityGO:00719001790.013
response to axon injuryGO:004867810.013
photoreceptor cell differentiationGO:004653020.013
negative regulation of organelle organizationGO:00106391260.013
protein oligomerizationGO:00512591730.013
Human
mitochondrion organizationGO:00070051560.013
sequestering of metal ionGO:0051238240.013
regulation of apoptotic signaling pathwayGO:20012331750.013
covalent chromatin modificationGO:00165692540.013
atp metabolic processGO:00460341760.013
release of cytoplasmic sequestered nf kappabGO:000858840.013
regulation of neurotransmitter secretionGO:004692830.013
establishment of protein localization to organelleGO:00725941720.013
regulation of multi organism processGO:00439001570.013
cation homeostasisGO:00550801890.013
behaviorGO:00076101120.013
regulation of protein catabolic processGO:00421761550.013
negative regulation of cell migrationGO:00303361020.013
cellular response to cytokine stimulusGO:00713451810.013
glycoprotein metabolic processGO:00091001100.013
regulation of ras gtpase activityGO:00323181280.013
muscle system processGO:0003012810.013
cell activationGO:00017752130.013
regulation of hormone levelsGO:00108171250.013
regulation of meiotic cell cycleGO:005144540.013
cell projection morphogenesisGO:00488581290.013
regulation of cell morphogenesisGO:00226041530.013
taxisGO:00423301570.013
positive regulation of locomotionGO:00400171860.013
regulation of neural precursor cell proliferationGO:200017740.013
cellular ion homeostasisGO:00068731680.013
protein autophosphorylationGO:00467771230.013
response to nitrogen compoundGO:19016981840.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
positive regulation of cell migrationGO:00303351720.012
negative regulation of cellular component movementGO:00512711060.012
alcohol metabolic processGO:00060661140.012
cell cycle phase transitionGO:00447701730.012
carboxylic acid biosynthetic processGO:0046394970.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.012
peptidyl tyrosine modificationGO:00182121700.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
neuron differentiationGO:00301821380.012
positive regulation of cell motilityGO:20001471770.012
regulation of axon guidanceGO:190266730.012
rna interferenceGO:001624640.012
regulation of cell projection organizationGO:00313441070.012
morphogenesis of a polarized epitheliumGO:000173830.012
peptidyl tyrosine phosphorylationGO:00181081700.012
sequestering of calcium ionGO:0051208170.012
long term memoryGO:000761620.012
negative regulation of cell differentiationGO:00455961710.012
cellular response to lipidGO:00713961270.012
meiosis iGO:000712740.012
microtubule cytoskeleton organizationGO:00002261760.012
positive regulation of ion transportGO:0043270870.012
cell fate determinationGO:000170930.012
negative regulation of transferase activityGO:00513481240.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
central nervous system developmentGO:00074171230.012
forebrain generation of neuronsGO:002187230.012
neuron developmentGO:00486661130.012
regulation of dephosphorylationGO:0035303960.012
organ formationGO:004864530.012
sensory perception of smellGO:000760820.012
inner ear morphogenesisGO:004247240.012
regulation of metal ion transportGO:00109591200.012
sulfur compound metabolic processGO:00067901010.012
regulation of protein maturationGO:19033171500.012
small molecule catabolic processGO:0044282920.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
sensory perception of painGO:001923340.012
immune system developmentGO:00025201950.012
dna repairGO:00062811980.012
positive regulation of hormone biosynthetic processGO:004688640.012
meiotic chromosome segregationGO:004513240.012
male genitalia developmentGO:003053910.012
primary neural tube formationGO:001402030.012
negative regulation of cell motilityGO:20001461040.012
establishment of protein localization to membraneGO:00901501210.012
cdc42 protein signal transductionGO:003248840.011
plasma membrane organizationGO:00070091150.011
angiogenesisGO:00015251470.011
mrna metabolic processGO:00160711750.011
phospholipid metabolic processGO:0006644990.011
positive regulation of secretion by cellGO:19035321080.011
neural tube formationGO:000184130.011
tube closureGO:006060630.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
mitotic cell cycle phase transitionGO:00447721620.011
cell cell signalingGO:00072671550.011
sleepGO:003043120.011
glycerolipid metabolic processGO:00464861070.011
negative regulation of synaptic transmissionGO:005080520.011
regulation of intracellular protein transportGO:00331571230.011
ameboidal type cell migrationGO:00016671350.011
regulation of protein processingGO:00706131500.011
positive regulation of proteolysisGO:00458621420.011
calcium ion transportGO:00068161470.011
visual behaviorGO:000763220.011
melanin metabolic processGO:000658210.011
monovalent inorganic cation transportGO:00156721280.011
lipid localizationGO:00108761060.011
endosomal transportGO:00161971290.011
chemotaxisGO:00069351570.011
glial cell migrationGO:000834740.011
dna replicationGO:00062601160.011
regulation of actin cytoskeleton organizationGO:00329561160.011
wnt signaling pathwayGO:00160551560.011
divalent inorganic cation homeostasisGO:00725071360.011
blood vessel developmentGO:00015681720.011
positive regulation of immune responseGO:00507781590.011
lung alveolus developmentGO:004828640.011
myoblast fusionGO:000752010.011
cell projection assemblyGO:00300311260.011
establishment or maintenance of bipolar cell polarityGO:006124520.011
somatic stem cell divisionGO:004810310.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
immune effector processGO:00022521590.011
organic anion transportGO:00157111030.011
regulation of protein complex assemblyGO:00432541470.011
regulation of homeostatic processGO:00328441210.011
negative regulation of protein processingGO:00109551420.011
negative regulation of kinase activityGO:00336731060.011
cofactor metabolic processGO:0051186870.011
head developmentGO:00603221080.011
positive regulation of cell adhesionGO:0045785840.011
erk1 and erk2 cascadeGO:00703711040.011
interspecies interaction between organismsGO:00444191560.011
response to virusGO:00096151260.011
somitogenesisGO:000175620.011
lipid transportGO:0006869900.011
ossificationGO:00015031210.011
nucleoside monophosphate catabolic processGO:00091251590.011
neural tube closureGO:000184330.011
cellular calcium ion homeostasisGO:00068741170.011
cell substrate adhesionGO:00315891320.011
regulation of transmembrane transportGO:00347621390.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
response to woundingGO:00096111680.011
regulation of cell divisionGO:00513021160.011
protein localization to nucleusGO:00345041360.011
cellular divalent inorganic cation homeostasisGO:00725031280.011
thymus developmentGO:004853830.011
establishment or maintenance of apical basal cell polarityGO:003508820.011
endocytosisGO:00068971590.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
circulatory system processGO:00030131130.011
atp catabolic processGO:00062001570.011
organelle fissionGO:00482851490.011
protein secretionGO:0009306980.011
cellular response to organic cyclic compoundGO:00714071270.010
rna splicingGO:00083801310.010
regulation of defense responseGO:00313471540.010
regulation of cysteine type endopeptidase activityGO:20001161270.010
establishment of planar polarityGO:000173630.010
sex determinationGO:000753030.010
patterning of blood vesselsGO:000156920.010
leukocyte activationGO:00453211640.010
regulation of axon extension involved in axon guidanceGO:004884120.010

HMGCLL1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.027
nervous system diseaseDOID:8634310.021
central nervous system diseaseDOID:3311860.021
sensory system diseaseDOID:00501552030.021
inherited metabolic disorderDOID:6552420.020
musculoskeletal system diseaseDOID:172230.019
disease of cellular proliferationDOID:145661740.017
cancerDOID:1621670.017
organ system cancerDOID:00506861640.016
eye and adnexa diseaseDOID:14921500.014
neurodegenerative diseaseDOID:12891020.014
eye diseaseDOID:56141490.013
cardiovascular system diseaseDOID:12871060.013
immune system diseaseDOID:29141550.013
muscular diseaseDOID:00800001140.013
muscle tissue diseaseDOID:661130.013
brain diseaseDOID:936730.013
retinal diseaseDOID:56791180.012
myopathyDOID:4231040.012
connective tissue diseaseDOID:651090.011
disease of mental healthDOID:150700.011