Homo sapiens

0 known processes

KIAA1045

KIAA1045

(Aliases: RP11-392A14.4,DKFZp434I2112)

KIAA1045 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
system processGO:00030083490.248
g protein coupled receptor signaling pathwayGO:00071862070.193
negative regulation of transmission of nerve impulseGO:005197010.176
cell cell signalingGO:00072671550.167
locomotory behaviorGO:000762610.162
transmembrane transportGO:00550853990.147
cation transmembrane transportGO:00986552380.143
inorganic cation transmembrane transportGO:00986621940.138
gamma aminobutyric acid signaling pathwayGO:000721430.123
ion transmembrane transportGO:00342203380.115
regulation of acrosome reactionGO:006004640.111
nervous system developmentGO:00073992930.102
metal ion transportGO:00300012720.102
neurological system processGO:00508771630.102
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathwayGO:000719640.098
regulation of synaptic plasticityGO:004816730.091
inorganic ion transmembrane transportGO:00986602310.091
positive regulation of acrosome reactionGO:200034440.090
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188430.087
positive regulation of synaptic transmissionGO:005080640.087
post embryonic developmentGO:000979120.086
cation transportGO:00068123310.074
positive regulation of transportGO:00510503360.070
secretionGO:00469032540.068
cellular amino acid metabolic processGO:00065201160.067
regulation of secretion by cellGO:19035301770.067
regulation of locomotionGO:00400123290.064
response to abiotic stimulusGO:00096283360.062
monovalent inorganic cation transportGO:00156721280.061
regulation of cellular amine metabolic processGO:0033238110.060
memoryGO:000761330.060
regulation of membrane potentialGO:0042391950.059
generation of neuronsGO:00486991520.059
regulation of transmission of nerve impulseGO:005196920.059
secretion by cellGO:00329402260.058
vesicle mediated transportGO:00161923710.057
regulation of atrial cardiac muscle cell membrane repolarizationGO:006037240.057
regulation of transmembrane transportGO:00347621390.057
limbic system developmentGO:002176130.057
amine metabolic processGO:0009308440.055
cellular amine metabolic processGO:0044106410.053
muscle system processGO:0003012810.053
neurogenesisGO:00220081690.053
synaptic transmissionGO:0007268610.052
cellular component morphogenesisGO:00329893140.051
cardiac muscle cell contractionGO:008600340.050
neurotransmitter secretionGO:000726940.050
regulation of cell developmentGO:00602841610.050
neuron differentiationGO:00301821380.049
matingGO:000761810.049
positive regulation of phosphorylationGO:00423273940.049
regulation of cell cycleGO:00517263930.048
cell projection organizationGO:00300302520.048
regulation of cellular amino acid metabolic processGO:000652160.048
actin filament based processGO:00300292240.048
regulation of secretionGO:00510461940.048
regulation of cellular component movementGO:00512703340.047
purine ribonucleoside catabolic processGO:00461303980.047
positive regulation of cellular amine metabolic processGO:003324070.046
positive regulation of cellular component organizationGO:00511303760.046
regulation of cell motilityGO:20001452990.046
regulation of neuronal synaptic plasticityGO:004816810.046
adult locomotory behaviorGO:000834410.045
ribonucleoside triphosphate catabolic processGO:00092033910.045
regulation of cellular ketone metabolic processGO:0010565500.044
cell developmentGO:00484683280.043
regulation of anatomical structure morphogenesisGO:00226032860.043
purine ribonucleoside metabolic processGO:00461284370.043
membrane organizationGO:00610242920.042
female gamete generationGO:000729220.042
purine nucleoside triphosphate metabolic processGO:00091444120.041
startle responseGO:000196430.041
regulation of ion transmembrane transportGO:00347651320.041
purine nucleoside catabolic processGO:00061523980.040
single organism membrane organizationGO:00448022680.040
organophosphate catabolic processGO:00464344300.040
purine nucleoside triphosphate catabolic processGO:00091463920.040
ribonucleoside catabolic processGO:00424544060.040
nucleoside phosphate catabolic processGO:19012924120.040
purine ribonucleotide catabolic processGO:00091544040.039
positive regulation of developmental processGO:00510943140.039
biological adhesionGO:00226103310.039
anion transportGO:00068201610.039
divalent inorganic cation transportGO:00725111580.039
nucleoside catabolic processGO:00091644080.038
purine ribonucleoside triphosphate catabolic processGO:00092073910.038
regulation of cell projection organizationGO:00313441070.038
purine containing compound catabolic processGO:00725234110.038
associative learningGO:000830610.038
small gtpase mediated signal transductionGO:0007264780.038
carbohydrate derivative biosynthetic processGO:19011372070.037
positive regulation of cell differentiationGO:00455972110.037
mitotic cell cycleGO:00002783260.037
sodium ion transmembrane transportGO:0035725590.037
central nervous system developmentGO:00074171230.037
purine nucleotide catabolic processGO:00061954050.037
organonitrogen compound biosynthetic processGO:19015662000.037
behaviorGO:00076101120.037
ribonucleotide catabolic processGO:00092614050.036
multicellular organismal agingGO:001025930.036
potassium ion transmembrane transportGO:0071805600.035
nucleotide catabolic processGO:00091664080.035
sensory perceptionGO:00076001030.035
detection of stimulusGO:0051606850.035
positive regulation of cellular amino acid metabolic processGO:004576430.035
ras protein signal transductionGO:0007265730.035
negative regulation of multicellular organismal processGO:00512413170.035
regulation of neuron differentiationGO:0045664700.035
cell morphogenesisGO:00009022960.034
positive regulation of hydrolase activityGO:00513453310.034
response to oxygen containing compoundGO:19017003690.034
cell adhesionGO:00071553250.034
organ formationGO:004864530.034
cellular potassium ion transportGO:0071804600.034
cellular ketone metabolic processGO:0042180800.034
response to nitrogen compoundGO:19016981840.034
negative regulation of catalytic activityGO:00430863350.034
regulation of protein localizationGO:00328802960.034
nucleoside triphosphate catabolic processGO:00091433940.033
regulation of purine nucleotide metabolic processGO:19005422640.033
single organism cellular localizationGO:19025803320.033
sodium ion transportGO:0006814610.033
regulation of kinase activityGO:00435493140.032
peripheral nervous system developmentGO:000742220.032
taxisGO:00423301570.032
multicellular organismal response to stressGO:003355510.032
glycosyl compound catabolic processGO:19016584130.032
regulation of cell differentiationGO:00455953930.032
neuropeptide signaling pathwayGO:0007218190.032
segmentationGO:003528240.032
regulation of neurotransmitter secretionGO:004692830.032
cytoplasmic transportGO:00164823790.032
regulation of ion transportGO:00432691890.032
lipid metabolic processGO:00066293810.031
determination of adult lifespanGO:000834020.031
neuromuscular junction developmentGO:000752830.031
regulation of nucleotide metabolic processGO:00061402690.031
mitotic cell cycle processGO:19030472860.031
ion homeostasisGO:00508012300.031
ribonucleoside triphosphate metabolic processGO:00091994120.031
neuron projection developmentGO:00311751060.031
negative regulation of phosphate metabolic processGO:00459362670.031
regulation of transferase activityGO:00513383550.030
rhythmic behaviorGO:000762220.030
regulation of cell migrationGO:00303342890.030
negative regulation of cellular component organizationGO:00511292350.030
metencephalon developmentGO:002203720.030
response to organic cyclic compoundGO:00140702040.030
neuron developmentGO:00486661130.029
cation homeostasisGO:00550801890.029
purine ribonucleoside triphosphate metabolic processGO:00092054110.029
regulation of sequence specific dna binding transcription factor activityGO:00510902110.029
mapk cascadeGO:00001652880.029
chemical homeostasisGO:00488783060.029
negative regulation of cellular protein metabolic processGO:00322693530.029
nucleoside triphosphate metabolic processGO:00091414220.029
negative regulation of synaptic transmissionGO:005080520.029
regulation of neurogenesisGO:0050767820.029
hindbrain developmentGO:003090230.029
regulation of cell morphogenesisGO:00226041530.029
divalent inorganic cation homeostasisGO:00725071360.028
muscle contractionGO:0006936730.028
positive regulation of secretionGO:00510471160.028
positive regulation of cell developmentGO:0010720920.028
positive regulation of catabolic processGO:00098963100.028
cellular response to endogenous stimulusGO:00714953360.028
potassium ion transportGO:0006813620.028
neuron fate commitmentGO:004866320.028
response to organonitrogen compoundGO:00102431560.027
sensory perception of painGO:001923340.027
positive regulation of secretion by cellGO:19035321080.027
oogenesisGO:004847720.027
cellular macromolecule catabolic processGO:00442653800.027
actin filament based movementGO:0030048170.027
dimeric g protein coupled receptor signaling pathwayGO:003804210.027
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193220.026
g protein coupled glutamate receptor signaling pathwayGO:000721680.026
long term memoryGO:000761620.026
nerve developmentGO:002167540.026
regulation of system processGO:00440571010.026
regulation of protein transportGO:00512232130.026
actin mediated cell contractionGO:0070252120.026
positive regulation of programmed cell deathGO:00430682490.026
cell divisionGO:00513011680.026
signal transduction by phosphorylationGO:00230142970.025
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187430.025
positive regulation of cell deathGO:00109422630.025
regulation of hormone levelsGO:00108171250.025
regulation of cell cycle processGO:00105642660.025
organic hydroxy compound metabolic processGO:19016151470.025
cellular cation homeostasisGO:00300031630.025
chemotaxisGO:00069351570.025
cellular ion homeostasisGO:00068731680.025
regulation of protein kinase activityGO:00458592890.025
regulation of proteolysisGO:00301622930.025
positive regulation of transferase activityGO:00513472270.024
calcium ion transmembrane transportGO:0070588760.024
anatomical structure formation involved in morphogenesisGO:00486462840.024
chromatin modificationGO:00165682980.024
regulation of metal ion transportGO:00109591200.024
head developmentGO:00603221080.024
cellular response to oxygen containing compoundGO:19017012760.024
nitrogen compound transportGO:00717051910.024
single organism cell adhesionGO:00986021790.024
cellular response to dna damage stimulusGO:00069743790.024
regenerationGO:003109940.024
gtp catabolic processGO:00061842370.023
cellular homeostasisGO:00197251960.023
regulation of cellular component biogenesisGO:00440872810.023
cardiovascular system developmentGO:00723582620.023
cerebral cortex gabaergic interneuron differentiationGO:002189210.023
regulation of cell growthGO:00015581350.023
positive regulation of protein phosphorylationGO:00019343130.023
intracellular protein transportGO:00068862700.023
positive regulation of nucleotide metabolic processGO:00459812300.023
protein catabolic processGO:00301633250.023
regulation of nucleoside metabolic processGO:00091182090.022
calcium ion transportGO:00068161470.022
protein localization to organelleGO:00333652800.022
positive regulation of nucleotide catabolic processGO:00308131850.022
forebrain regionalizationGO:002187130.022
positive regulation of purine nucleotide metabolic processGO:19005442270.022
cell projection morphogenesisGO:00488581290.022
positive regulation of cellular catabolic processGO:00313312840.022
regulation of purine nucleotide catabolic processGO:00331212050.022
cellular chemical homeostasisGO:00550821800.022
defense responseGO:00069523150.022
microtubule based processGO:00070172100.022
organophosphate biosynthetic processGO:00904071630.022
endomembrane system organizationGO:00102561960.022
positive regulation of locomotionGO:00400171860.022
guanosine containing compound metabolic processGO:19010682440.022
regulation of establishment of protein localizationGO:00702012420.022
cell part morphogenesisGO:00329901370.022
positive regulation of cellular component movementGO:00512721810.022
spinal cord developmentGO:002151040.022
long term synaptic potentiationGO:006029110.022
enzyme linked receptor protein signaling pathwayGO:00071673030.021
chromatin organizationGO:00063253510.021
protein oligomerizationGO:00512591730.021
regulation of nervous system developmentGO:0051960880.021
negative regulation of programmed cell deathGO:00430693210.021
guanosine containing compound catabolic processGO:19010692390.021
negative regulation of cell deathGO:00605483450.021
ameboidal type cell migrationGO:00016671350.021
regulation of response to external stimulusGO:00321012220.021
positive regulation of cytokine productionGO:00018191670.021
signal releaseGO:0023061700.021
regulation of growthGO:00400081650.021
cellular response to cytokine stimulusGO:00713451810.021
regulation of behaviorGO:0050795820.021
immune responseGO:00069553070.021
cell morphogenesis involved in differentiationGO:00009041440.021
negative regulation of protein modification processGO:00314002000.021
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.021
dephosphorylationGO:00163112090.021
regulation of nucleotide catabolic processGO:00308112050.021
regulation of vesicle mediated transportGO:00606271300.020
oocyte differentiationGO:000999420.020
circulatory system developmentGO:00723592620.020
cell cycle phase transitionGO:00447701730.020
mitotic cell cycle phase transitionGO:00447721620.020
positive regulation of axon extensionGO:004577340.020
protein autophosphorylationGO:00467771230.020
regulation of cytokine productionGO:00018172320.020
negative regulation of phosphorus metabolic processGO:00105632670.020
regulation of meiotic cell cycleGO:005144540.020
regulation of multi organism processGO:00439001570.020
forebrain generation of neuronsGO:002187230.020
negative regulation of intracellular signal transductionGO:19025321830.020
positive regulation of apoptotic processGO:00430652460.020
epithelial cell migrationGO:00106311190.020
positive regulation of cell cycleGO:00457871400.020
cellular divalent inorganic cation homeostasisGO:00725031280.020
covalent chromatin modificationGO:00165692540.019
cell growthGO:00160491600.019
growthGO:00400072020.019
negative regulation of protein metabolic processGO:00512483910.019
carbohydrate metabolic processGO:00059752070.019
establishment of protein localization to organelleGO:00725941720.019
protein modification by small protein conjugationGO:00324463420.019
motor neuron axon guidanceGO:000804520.019
positive regulation of protein kinase activityGO:00458601900.019
calcium ion homeostasisGO:00550741220.019
action potentialGO:0001508340.019
cell fate determinationGO:000170930.019
negative regulation of gliogenesisGO:001401430.019
neuroblast proliferationGO:000740540.019
glial cell migrationGO:000834740.019
organic anion transportGO:00157111030.019
regulation of cell morphogenesis involved in differentiationGO:0010769830.019
hormone secretionGO:0046879650.019
cerebellum developmentGO:002154920.019
cardiac muscle contractionGO:0060048340.019
positive regulation of cell proliferationGO:00082843010.019
divalent metal ion transportGO:00708381520.019
regulation of heart rateGO:0002027380.019
nucleotide biosynthetic processGO:00091651090.019
response to lipidGO:00339932060.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
negative regulation of neurological system processGO:003164520.019
regulation of gtpase activityGO:00430871800.018
cellular response to histamineGO:007142030.018
cellular metal ion homeostasisGO:00068751460.018
rho protein signal transductionGO:0007266260.018
regulation of cellular response to stressGO:00801352440.018
cellular protein catabolic processGO:00442572610.018
regulation of gtp catabolic processGO:00331241800.018
amide transportGO:0042886760.018
regulation of heart induction by regulation of canonical wnt signaling pathwayGO:009008110.018
gtp metabolic processGO:00460392390.018
positive regulation of mapk cascadeGO:00434101900.018
actin cytoskeleton organizationGO:00300362070.018
circadian behaviorGO:004851220.018
positive regulation of nucleoside metabolic processGO:00459791860.018
cellular response to nitrogen compoundGO:19016991440.018
regulation of ras protein signal transductionGO:00465781550.018
neuron projection regenerationGO:003110210.018
brain developmentGO:0007420970.018
reproductive processGO:00224141060.018
photoreceptor cell differentiationGO:004653020.018
positive regulation of purine nucleotide catabolic processGO:00331231850.017
epithelium developmentGO:00604292270.017
blastoderm segmentationGO:000735020.017
regulation of reactive oxygen species biosynthetic processGO:190342630.017
regulation of feeding behaviorGO:006025930.017
wnt signaling pathwayGO:00160551560.017
multicellular organismal signalingGO:0035637340.017
cellular macromolecular complex assemblyGO:00346223240.017
regulation of intracellular transportGO:00323861950.017
single organismal cell cell adhesionGO:00163371480.017
negative regulation of cellular amine metabolic processGO:003323930.017
regulation of mapk cascadeGO:00434082620.017
regulation of axon guidanceGO:190266730.017
negative regulation of apoptotic processGO:00430663160.017
hippocampus developmentGO:002176610.017
response to axon injuryGO:004867810.017
visual learningGO:000854210.017
nucleoside phosphate biosynthetic processGO:19012931090.017
cytokine productionGO:00018162470.017
anterior posterior axis specificationGO:000994820.017
negative regulation of organelle organizationGO:00106391260.017
positive regulation of organelle organizationGO:00106381950.017
regulation of neural precursor cell proliferationGO:200017740.017
protein ubiquitinationGO:00165673140.017
lipid biosynthetic processGO:00086101770.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.017
cognitionGO:0050890430.016
protein targetingGO:00066051870.016
regulation of protein serine threonine kinase activityGO:00719001790.016
morphogenesis of embryonic epitheliumGO:001633140.016
specification of organ identityGO:001009230.016
regulation of neuron projection developmentGO:0010975570.016
positive regulation of ras gtpase activityGO:00323201170.016
positive regulation of gtpase activityGO:00435471660.016
response to cytokineGO:00340972320.016
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.016
negative regulation of cell proliferationGO:00082852280.016
negative regulation of voltage gated calcium channel activityGO:190138640.016
regulation of mitotic cell cycleGO:00073461890.016
positive regulation of gtp catabolic processGO:00331261660.016
tachykinin receptor signaling pathwayGO:000721730.016
ribose phosphate biosynthetic processGO:0046390820.016
regulation of cell adhesionGO:00301551660.016
regulation of actin filament based processGO:00329701410.016
metal ion homeostasisGO:00550651690.016
oocyte developmentGO:004859910.016
apoptotic signaling pathwayGO:00971902680.016
negative regulation of cellular component movementGO:00512711060.016
organelle fissionGO:00482851490.015
forebrain neuron differentiationGO:002187930.015
histone modificationGO:00165702510.015
negative regulation of cell cycleGO:00457861930.015
reactive oxygen species metabolic processGO:0072593750.015
positive regulation of kinase activityGO:00336742040.015
cyclic nucleotide metabolic processGO:0009187820.015
regulation of transporter activityGO:0032409820.015
cerebral cortex cell migrationGO:002179530.015
cellular response to ammonium ionGO:007124240.015
cellular calcium ion homeostasisGO:00068741170.015
camp metabolic processGO:0046058610.015
single organism carbohydrate metabolic processGO:00447231930.015
spermatid differentiationGO:004851540.015
tissue migrationGO:00901301190.015
tripartite regional subdivisionGO:000735120.015
protein localization to membraneGO:00726571600.015
regulation of dna metabolic processGO:00510521530.015
visual behaviorGO:000763220.015
canonical wnt signaling pathwayGO:00600701160.015
response to radiationGO:00093141510.015
heart formationGO:006091420.015
reactive nitrogen species metabolic processGO:200105730.015
regulation of cytoskeleton organizationGO:00514931770.015
posttranscriptional regulation of gene expressionGO:00106082130.015
positive regulation of cell projection organizationGO:0031346640.015
glutamate receptor signaling pathwayGO:0007215230.015
epithelial cell differentiationGO:00308551410.015
cellular response to organonitrogen compoundGO:00714171240.015
detection of stimulus involved in sensory perceptionGO:0050906430.015
cell activationGO:00017752130.015
epithelium migrationGO:00901321190.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
peptide transportGO:0015833740.015
thymus developmentGO:004853830.015
cell projection assemblyGO:00300311260.015
response to hormoneGO:00097251750.015
response to salt stressGO:000965130.014
positive regulation of cell cycle processGO:00900681060.014
regulation of ras gtpase activityGO:00323181280.014
microtubule cytoskeleton organizationGO:00002261760.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
positive regulation of protein transportGO:00512221350.014
anion transmembrane transportGO:0098656760.014
striated muscle contractionGO:0006941520.014
transmission of nerve impulseGO:0019226110.014
regulation of hormone secretionGO:0046883570.014
endocytosisGO:00068971590.014
hormone transportGO:0009914680.014
negative regulation of locomotionGO:00400131180.014
positive regulation of protein serine threonine kinase activityGO:00719021190.014
positive regulation of monocyte chemotactic protein 1 productionGO:007163930.014
negative regulation of cell motilityGO:20001461040.014
atp metabolic processGO:00460341760.014
sensory perception of light stimulusGO:0050953350.014
maintenance of locationGO:00512351120.014
anterior posterior axis specification embryoGO:000859520.014
regulation of blood circulationGO:1903522590.014
membrane hyperpolarizationGO:006008110.014
acrosomal vesicle exocytosisGO:006047830.014
positive regulation of ion transportGO:0043270870.014
nucleoside monophosphate catabolic processGO:00091251590.014
negative regulation of developmental processGO:00510932470.014
negative regulation of cell migrationGO:00303361020.014
negative regulation of cell differentiationGO:00455961710.014
regulation of homeostatic processGO:00328441210.014
cellular response to hormone stimulusGO:00328701250.014
positive regulation of neurogenesisGO:0050769490.014
rna processingGO:00063962550.014
regulation of postsynaptic membrane potentialGO:006007810.014
cranial nerve developmentGO:002154540.014
negative regulation of phosphorylationGO:00423261740.014
purine nucleoside monophosphate catabolic processGO:00091281580.014
protein maturationGO:00516042330.014
detection of chemical stimulusGO:0009593550.014
cellular response to growth factor stimulusGO:00713631970.014
sex determinationGO:000753030.014
regulation of glial cell differentiationGO:004568530.014
oxidation reduction processGO:00551143960.014
spermatid developmentGO:000728640.013
vasculature developmentGO:00019441810.013
blood circulationGO:00080151130.013
positive regulation of cell motilityGO:20001471770.013
purine containing compound biosynthetic processGO:0072522880.013
nucleoside monophosphate metabolic processGO:00091231910.013
negative regulation of transportGO:00510511760.013
forelimb morphogenesisGO:003513640.013
reactive oxygen species biosynthetic processGO:190340940.013
purine ribonucleoside monophosphate metabolic processGO:00091671860.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
response to external biotic stimulusGO:00432072610.013
response to growth factorGO:00708482050.013
cellular component disassemblyGO:0022411920.013
innate immune responseGO:00450871780.013
nuclear divisionGO:00002801280.013
cellular response to organic cyclic compoundGO:00714071270.013
cardiac cell fate determinationGO:006091330.013
response to oxygen levelsGO:00704821000.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
organelle assemblyGO:00709251760.013
receptor metabolic processGO:0043112810.013
camp biosynthetic processGO:0006171470.013
positive regulation of immune system processGO:00026842830.013
cellular protein complex assemblyGO:00436231880.013
regulation of protein complex assemblyGO:00432541470.013
circulatory system processGO:00030131130.013
establishment of protein localization to membraneGO:00901501210.013
regulation of meiosisGO:004002030.013
mitotic nuclear divisionGO:00070671190.013
regulation of endopeptidase activityGO:00525481700.013
peptidyl tyrosine phosphorylationGO:00181081700.013

KIAA1045 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.035
central nervous system diseaseDOID:3311860.035
sensory system diseaseDOID:00501552030.022
disease of cellular proliferationDOID:145661740.020
eye and adnexa diseaseDOID:14921500.017
retinal diseaseDOID:56791180.017
eye diseaseDOID:56141490.017
neurodegenerative diseaseDOID:12891020.015
cancerDOID:1621670.015
brain diseaseDOID:936730.015
epilepsy syndromeDOID:1826410.015
organ system cancerDOID:00506861640.014
disease of metabolismDOID:00146672950.014
disease of mental healthDOID:150700.014