Homo sapiens

80 known processes

MFN2

mitofusin 2

(Aliases: MARF,CPRP1,CMT2A,KIAA0214,CMT2A2,HSG)

MFN2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitochondrial fissionGO:0000266140.340
regulation of mitochondrion organizationGO:0010821540.205
protein localization to organelleGO:00333652800.195
positive regulation of mitochondrion organizationGO:0010822300.190
positive regulation of mitochondrial fissionGO:009014170.167
protein localization to mitochondrionGO:0070585250.152
positive regulation of developmental processGO:00510943140.149
regulation of mitochondrial fissionGO:009014080.135
regulation of anatomical structure morphogenesisGO:00226032860.128
positive regulation of organelle organizationGO:00106381950.093
organelle fissionGO:00482851490.091
negative regulation of developmental processGO:00510932470.084
oxidation reduction processGO:00551143960.080
protein autoubiquitinationGO:0051865370.069
cell agingGO:0007569520.062
positive regulation of cellular component organizationGO:00511303760.059
determination of adult lifespanGO:000834020.058
cytoplasmic transportGO:00164823790.047
nucleoside triphosphate metabolic processGO:00091414220.045
locomotory behaviorGO:000762610.045
multicellular organismal agingGO:001025930.042
purine ribonucleoside metabolic processGO:00461284370.040
cellular amino acid metabolic processGO:00065201160.040
amine metabolic processGO:0009308440.039
purine nucleoside triphosphate metabolic processGO:00091444120.039
mitotic cell cycleGO:00002783260.037
protein catabolic processGO:00301633250.037
cellular ketone metabolic processGO:0042180800.037
regulation of cell agingGO:0090342180.037
cellular amine metabolic processGO:0044106410.036
small gtpase mediated signal transductionGO:0007264780.035
cellular macromolecule catabolic processGO:00442653800.034
ras protein signal transductionGO:0007265730.034
post embryonic developmentGO:000979120.034
neuromuscular junction developmentGO:000752830.034
nucleotide catabolic processGO:00091664080.033
regulation of cellular amino acid metabolic processGO:000652160.033
regulation of cellular ketone metabolic processGO:0010565500.033
regulation of cellular amine metabolic processGO:0033238110.033
ribonucleotide catabolic processGO:00092614050.032
membrane organizationGO:00610242920.031
intracellular protein transportGO:00068862700.030
negative regulation of protein metabolic processGO:00512483910.030
regulation of protein localizationGO:00328802960.030
proteolysis involved in cellular protein catabolic processGO:00516032440.029
agingGO:0007568660.029
nucleoside phosphate catabolic processGO:19012924120.029
nucleoside triphosphate catabolic processGO:00091433940.028
positive regulation of hydrolase activityGO:00513453310.028
generation of precursor metabolites and energyGO:0006091680.028
organophosphate catabolic processGO:00464344300.028
purine ribonucleoside triphosphate metabolic processGO:00092054110.027
protein ubiquitinationGO:00165673140.027
female gamete generationGO:000729220.027
purine ribonucleoside triphosphate catabolic processGO:00092073910.027
positive regulation of phosphorylationGO:00423273940.026
nucleoside catabolic processGO:00091644080.026
memoryGO:000761330.026
purine ribonucleoside catabolic processGO:00461303980.026
cell growthGO:00160491600.026
nucleocytoplasmic transportGO:00069131760.025
purine nucleotide catabolic processGO:00061954050.025
ribonucleoside triphosphate catabolic processGO:00092033910.025
mitochondrion organizationGO:00070051560.025
cellular lipid metabolic processGO:00442553030.025
oogenesisGO:004847720.025
positive regulation of cellular amine metabolic processGO:003324070.025
negative regulation of catalytic activityGO:00430863350.024
segmentationGO:003528240.024
single organism cellular localizationGO:19025803320.024
regulation of cell growthGO:00015581350.024
positive regulation of cellular amino acid metabolic processGO:004576430.023
protein maturationGO:00516042330.023
purine nucleoside catabolic processGO:00061523980.023
spermatid differentiationGO:004851540.023
adult locomotory behaviorGO:000834410.023
mitotic cell cycle processGO:19030472860.023
negative regulation of programmed cell deathGO:00430693210.023
cardiac muscle cell contractionGO:008600340.023
cation transportGO:00068123310.023
purine containing compound catabolic processGO:00725234110.022
guanosine containing compound catabolic processGO:19010692390.022
cellular macromolecular complex assemblyGO:00346223240.022
negative regulation of cell deathGO:00605483450.022
energy derivation by oxidation of organic compoundsGO:0015980430.022
regenerationGO:003109940.022
cation transmembrane transportGO:00986552380.022
cell developmentGO:00484683280.022
response to abiotic stimulusGO:00096283360.022
ubiquitin dependent protein catabolic processGO:00065112060.022
cell projection organizationGO:00300302520.022
purine ribonucleotide catabolic processGO:00091544040.021
cell morphogenesisGO:00009022960.021
organonitrogen compound biosynthetic processGO:19015662000.021
chemical homeostasisGO:00488783060.021
regulation of purine nucleotide metabolic processGO:19005422640.021
positive regulation of programmed cell deathGO:00430682490.021
succinyl coa metabolic processGO:000610410.021
nervous system developmentGO:00073992930.020
system processGO:00030083490.020
carbohydrate derivative biosynthetic processGO:19011372070.020
negative regulation of apoptotic processGO:00430663160.020
endomembrane system organizationGO:00102561960.020
protein modification by small protein conjugationGO:00324463420.020
glycosyl compound catabolic processGO:19016584130.020
negative regulation of cellular protein metabolic processGO:00322693530.020
ribonucleoside catabolic processGO:00424544060.020
lipid metabolic processGO:00066293810.020
ion transmembrane transportGO:00342203380.020
ribonucleoside triphosphate metabolic processGO:00091994120.019
regulation of transferase activityGO:00513383550.019
transmembrane transportGO:00550853990.019
tricarboxylic acid metabolic processGO:007235040.019
rna interferenceGO:001624640.019
microtubule based processGO:00070172100.019
response to oxygen containing compoundGO:19017003690.019
proteasomal protein catabolic processGO:00104981760.019
sulfur compound metabolic processGO:00067901010.019
oocyte developmentGO:004859910.019
blastoderm segmentationGO:000735020.019
maintenance of locationGO:00512351120.019
photoreceptor cell differentiationGO:004653020.019
rhythmic behaviorGO:000762220.019
anterior posterior axis specificationGO:000994820.018
regulation of apoptotic signaling pathwayGO:20012331750.018
negative regulation of intracellular signal transductionGO:19025321830.018
citrate metabolic processGO:000610120.018
cell adhesionGO:00071553250.018
positive regulation of apoptotic processGO:00430652460.018
secretion by cellGO:00329402260.018
purine nucleoside monophosphate metabolic processGO:00091261860.018
nuclear transportGO:00511691790.018
single organism membrane organizationGO:00448022680.017
actin filament based processGO:00300292240.017
monocarboxylic acid metabolic processGO:00327871850.017
protein deubiquitinationGO:0016579790.017
negative regulation of cellular amine metabolic processGO:003323930.017
oocyte differentiationGO:000999420.017
mapk cascadeGO:00001652880.017
mitochondrial transportGO:0006839600.017
rna processingGO:00063962550.017
atp metabolic processGO:00460341760.017
regulation of kinase activityGO:00435493140.017
negative regulation of phosphate metabolic processGO:00459362670.017
small molecule biosynthetic processGO:00442831570.017
inorganic ion transmembrane transportGO:00986602310.017
regulation of cellular component biogenesisGO:00440872810.016
posttranscriptional regulation of gene expressionGO:00106082130.016
positive regulation of protein phosphorylationGO:00019343130.016
dicarboxylic acid metabolic processGO:0043648290.016
carbohydrate metabolic processGO:00059752070.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
dephosphorylationGO:00163112090.016
regulation of nucleotide metabolic processGO:00061402690.016
apoptotic signaling pathwayGO:00971902680.016
purine nucleoside triphosphate catabolic processGO:00091463920.016
regulation of protein kinase activityGO:00458592890.016
nucleoside monophosphate metabolic processGO:00091231910.016
sleepGO:003043120.016
regulation of cell cycleGO:00517263930.016
positive regulation of cellular catabolic processGO:00313312840.016
peripheral nervous system developmentGO:000742220.016
nitrogen compound transportGO:00717051910.016
covalent chromatin modificationGO:00165692540.016
cellular protein complex assemblyGO:00436231880.016
regulation of intracellular transportGO:00323861950.015
metal ion transportGO:00300012720.015
carboxylic acid biosynthetic processGO:0046394970.015
regulation of small gtpase mediated signal transductionGO:00510561560.015
positive regulation of catabolic processGO:00098963100.015
circadian behaviorGO:004851220.015
vesicle mediated transportGO:00161923710.015
signal transduction by phosphorylationGO:00230142970.015
reactive nitrogen species metabolic processGO:200105730.015
nucleus localizationGO:005164710.015
nuclear migrationGO:000709710.015
anion transportGO:00068201610.015
neurotransmitter secretionGO:000726940.015
negative regulation of organelle organizationGO:00106391260.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
positive regulation of transportGO:00510503360.015
biological adhesionGO:00226103310.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
positive regulation of cell deathGO:00109422630.015
response to fungusGO:000962040.015
protein polyubiquitinationGO:00002091100.015
reactive oxygen species metabolic processGO:0072593750.015
inner ear morphogenesisGO:004247240.015
guanosine containing compound metabolic processGO:19010682440.014
secretionGO:00469032540.014
startle responseGO:000196430.014
regulation of mapk cascadeGO:00434082620.014
protein targetingGO:00066051870.014
negative regulation of cellular component organizationGO:00511292350.014
anterior posterior axis specification embryoGO:000859520.014
positive regulation of nucleotide metabolic processGO:00459812300.014
establishment of nucleus localizationGO:004002310.014
negative regulation of transportGO:00510511760.014
organelle localizationGO:0051640840.014
regulation of cell differentiationGO:00455953930.014
cellular component disassemblyGO:0022411920.014
positive regulation of immune system processGO:00026842830.014
actin mediated cell contractionGO:0070252120.014
regulation of transporter activityGO:0032409820.014
tripartite regional subdivisionGO:000735120.014
cell fate determinationGO:000170930.014
neurological system processGO:00508771630.014
nuclear divisionGO:00002801280.014
positive regulation of gtp catabolic processGO:00331261660.014
compound eye developmentGO:004874910.014
negative regulation of phosphorus metabolic processGO:00105632670.014
inorganic cation transmembrane transportGO:00986621940.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
regulation of neural precursor cell proliferationGO:200017740.014
regulation of cellular component movementGO:00512703340.014
negative regulation of growthGO:0045926970.013
regulation of nucleotide catabolic processGO:00308112050.013
hindbrain developmentGO:003090230.013
regulation of secretionGO:00510461940.013
associative learningGO:000830610.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
cellular ion homeostasisGO:00068731680.013
microtubule cytoskeleton organizationGO:00002261760.013
rho protein signal transductionGO:0007266260.013
lipid biosynthetic processGO:00086101770.013
regulation of ras protein signal transductionGO:00465781550.013
sequestering of metal ionGO:0051238240.013
regulation of neurotransmitter secretionGO:004692830.013
organophosphate biosynthetic processGO:00904071630.013
negative regulation of phosphorylationGO:00423261740.013
regulation of cell cycle processGO:00105642660.013
cellular response to oxygen containing compoundGO:19017012760.013
monovalent inorganic cation transportGO:00156721280.013
matingGO:000761810.013
dna repairGO:00062811980.013
actin filament based movementGO:0030048170.013
positive regulation of nucleotide catabolic processGO:00308131850.013
fatty acid metabolic processGO:00066311150.013
cellular component morphogenesisGO:00329893140.013
response to external biotic stimulusGO:00432072610.013
regulation of protein catabolic processGO:00421761550.013
negative regulation of proteolysisGO:00458611320.013
cellular response to nutrient levelsGO:0031669690.013
reactive oxygen species biosynthetic processGO:190340940.013
organ formationGO:004864530.013
single organism carbohydrate metabolic processGO:00447231930.013
tricarboxylic acid cycleGO:000609940.013
meiotic chromosome segregationGO:004513240.013
regulation of gtpase activityGO:00430871800.013
mrna metabolic processGO:00160711750.013
protein processingGO:00164852260.013
regulation of immune responseGO:00507762010.013
nerve developmentGO:002167540.012
metencephalon developmentGO:002203720.012
response to axon injuryGO:004867810.012
small molecule catabolic processGO:0044282920.012
protein localization to membraneGO:00726571600.012
single organism membrane fusionGO:0044801370.012
embryonic epithelial tube formationGO:000183840.012
cell projection morphogenesisGO:00488581290.012
negative regulation of hydrolase activityGO:00513461820.012
syncytium formation by plasma membrane fusionGO:000076820.012
regulation of synaptic plasticityGO:004816730.012
regulation of nucleoside metabolic processGO:00091182090.012
regulation of membrane potentialGO:0042391950.012
positive regulation of gtpase activityGO:00435471660.012
neurogenesisGO:00220081690.012
negative regulation of protein processingGO:00109551420.012
epithelium developmentGO:00604292270.012
response to hormoneGO:00097251750.012
cellular response to endogenous stimulusGO:00714953360.012
anterograde axon cargo transportGO:000808910.012
metal ion homeostasisGO:00550651690.012
sequestering of calcium ionGO:0051208170.012
positive regulation of synaptic transmissionGO:005080640.012
cardiovascular system developmentGO:00723582620.012
visual behaviorGO:000763220.012
positive regulation of secretionGO:00510471160.012
establishment of protein localization to membraneGO:00901501210.012
regulation of purine nucleotide catabolic processGO:00331212050.012
cell cell signalingGO:00072671550.012
regulation of ion transportGO:00432691890.011
axon cargo transportGO:000808820.011
regulation of cytokine productionGO:00018172320.011
tissue regenerationGO:004224630.011
regulation of growthGO:00400081650.011
divalent metal ion transportGO:00708381520.011
organic acid biosynthetic processGO:0016053970.011
defense responseGO:00069523150.011
positive regulation of nucleoside metabolic processGO:00459791860.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
cofactor biosynthetic processGO:0051188310.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
mitotic nuclear divisionGO:00070671190.011
ion homeostasisGO:00508012300.011
cellular metal ion homeostasisGO:00068751460.011
plasma membrane organizationGO:00070091150.011
organelle assemblyGO:00709251760.011
mitochondrial membrane organizationGO:0007006400.011
calcium ion transportGO:00068161470.011
embryo developmentGO:00097901230.011
autophagyGO:0006914880.011
response to cytokineGO:00340972320.011
long term memoryGO:000761620.011
atp catabolic processGO:00062001570.011
regulation of peptidase activityGO:00525471800.011
regulation of secretion by cellGO:19035301770.011
negative regulation of gliogenesisGO:001401430.011
positive regulation of transferase activityGO:00513472270.011
regulation of cell morphogenesisGO:00226041530.011
cellular response to misfolded proteinGO:007121820.011
immune responseGO:00069553070.011
regulation of cell migrationGO:00303342890.011
regulation of ras gtpase activityGO:00323181280.011
generation of neuronsGO:00486991520.011
release of cytoplasmic sequestered nf kappabGO:000858840.011
positive regulation of proteolysisGO:00458621420.011
response to nitrogen compoundGO:19016981840.011
cerebellum developmentGO:002154920.011
response to organic cyclic compoundGO:00140702040.011
protein acylationGO:00435431380.011
neural tube formationGO:000184130.011
regulation of gtp catabolic processGO:00331241800.011
regulation of cytoskeleton organizationGO:00514931770.011
thymus developmentGO:004853830.011
regulation of mitotic cell cycleGO:00073461890.011
response to inorganic substanceGO:00100351270.011
endocytosisGO:00068971590.011
cell projection assemblyGO:00300311260.011
motor neuron axon guidanceGO:000804520.011
detection of stimulusGO:0051606850.011
positive regulation of protein transportGO:00512221350.011
regulation of protein complex assemblyGO:00432541470.011
protein modification by small protein removalGO:0070646920.011
cation homeostasisGO:00550801890.011
lipid localizationGO:00108761060.011
neuroblast proliferationGO:000740540.011
regulation of protein transportGO:00512232130.011
cell activationGO:00017752130.011
neuron developmentGO:00486661130.011
positive regulation of kinase activityGO:00336742040.010
regulation of cellular response to stressGO:00801352440.010
spindle elongationGO:005123140.010
2 oxoglutarate metabolic processGO:000610340.010
extrinsic apoptotic signaling pathwayGO:00971911190.010
cellular response to external stimulusGO:00714961110.010
regulation of meiosisGO:004002030.010
establishment of planar polarityGO:000173630.010
somitogenesisGO:000175620.010
response to oxidative stressGO:00069791210.010
glycoprotein biosynthetic processGO:0009101910.010
growthGO:00400072020.010
epidermis morphogenesisGO:004873030.010
response to other organismGO:00517072610.010
regulation of dna metabolic processGO:00510521530.010
nucleoside monophosphate catabolic processGO:00091251590.010
circadian sleep wake cycleGO:004274520.010
protein localization to nucleusGO:00345041360.010
i kappab kinase nf kappab signalingGO:00072491660.010
positive regulation of reactive oxygen species biosynthetic processGO:190342820.010
positive regulation of secretion by cellGO:19035321080.010
phospholipid metabolic processGO:0006644990.010
cell part morphogenesisGO:00329901370.010
somatic muscle developmentGO:000752510.010
circadian sleep wake cycle sleepGO:005080220.010
striated muscle contractionGO:0006941520.010
nuclear exportGO:0051168690.010
morphogenesis of embryonic epitheliumGO:001633140.010
innate immune responseGO:00450871780.010
positive regulation of protein kinase activityGO:00458601900.010
melanin metabolic processGO:000658210.010
response to hypoxiaGO:0001666960.010
regulation of cytoplasmic transportGO:19036491490.010
regulation of intracellular protein transportGO:00331571230.010
stress activated protein kinase signaling cascadeGO:0031098940.010
spermatid developmentGO:000728640.010
synaptic vesicle endocytosisGO:004848820.010
regulation of chromosome organizationGO:00330441030.010

MFN2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.037
central nervous system diseaseDOID:3311860.037
disease of metabolismDOID:00146672950.037
sensory system diseaseDOID:00501552030.036
inherited metabolic disorderDOID:6552420.035
eye diseaseDOID:56141490.034
eye and adnexa diseaseDOID:14921500.034
musculoskeletal system diseaseDOID:172230.030
muscle tissue diseaseDOID:661130.023
muscular diseaseDOID:00800001140.023
myopathyDOID:4231040.023
cancerDOID:1621670.020
disease of cellular proliferationDOID:145661740.020
organ system cancerDOID:00506861640.020
neurodegenerative diseaseDOID:12891020.019
retinal diseaseDOID:56791180.018
retinal degenerationDOID:8466890.017
cardiovascular system diseaseDOID:12871060.015
immune system diseaseDOID:29141550.012
muscular dystrophyDOID:9884510.012
brain diseaseDOID:936730.011
heart diseaseDOID:114680.011
retinitis pigmentosaDOID:10584510.010
neuropathyDOID:870520.008
neuromuscular diseaseDOID:440380.007
charcot marie tooth diseaseDOID:10595330.005
charcot marie tooth disease type 2DOID:0050539150.003