Homo sapiens

46 known processes

MUS81

MUS81 endonuclease homolog (S. cerevisiae)

(Aliases: FLJ21012,SLX3,FLJ44872)

MUS81 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to dna integrity checkpoint signalingGO:007240240.993
double strand break repair via single strand annealingGO:004500240.988
response to dna damage checkpoint signalingGO:007242340.978
nucleotide excision repair dna incisionGO:003368370.954
cellular response to biotic stimulusGO:0071216710.917
response to intra s dna damage checkpoint signalingGO:007242940.886
dna catabolic processGO:0006308490.878
cellular response to endogenous stimulusGO:00714953360.810
nucleic acid phosphodiester bond hydrolysisGO:00903051020.746
response to biotic stimulusGO:00096072760.739
nucleotide excision repairGO:0006289310.677
response to cell cycle checkpoint signalingGO:007239640.575
double strand break repair via homologous recombinationGO:0000724500.512
double strand break repairGO:00063021010.497
cellular response to dna damage stimulusGO:00069743790.486
dna repairGO:00062811980.482
negative regulation of homeostatic processGO:0032845590.306
recombinational repairGO:0000725500.304
dna double strand break processingGO:0000729100.251
non recombinational repairGO:0000726140.218
sex determinationGO:000753030.213
nucleoside triphosphate metabolic processGO:00091414220.194
post embryonic developmentGO:000979120.178
regulation of telomere maintenanceGO:0032204130.154
negative regulation of organelle organizationGO:00106391260.113
nucleotide catabolic processGO:00091664080.110
anatomical structure homeostasisGO:00602491000.103
negative regulation of telomere maintenanceGO:003220590.098
purine ribonucleoside catabolic processGO:00461303980.095
negative regulation of chromosome organizationGO:2001251480.092
regulation of dna metabolic processGO:00510521530.092
purine ribonucleoside triphosphate metabolic processGO:00092054110.084
ribonucleoside triphosphate catabolic processGO:00092033910.081
replicative cell agingGO:000130230.080
glycosyl compound catabolic processGO:19016584130.073
organophosphate catabolic processGO:00464344300.071
determination of adult lifespanGO:000834020.066
morphogenesis of embryonic epitheliumGO:001633140.059
ribonucleoside catabolic processGO:00424544060.056
purine ribonucleotide catabolic processGO:00091544040.056
ras protein signal transductionGO:0007265730.054
ribonucleotide catabolic processGO:00092614050.053
positive regulation of catabolic processGO:00098963100.052
purine nucleoside triphosphate metabolic processGO:00091444120.051
purine ribonucleoside monophosphate catabolic processGO:00091691580.050
purine ribonucleoside metabolic processGO:00461284370.049
atp catabolic processGO:00062001570.048
cellular amino acid metabolic processGO:00065201160.047
multicellular organismal agingGO:001025930.045
positive regulation of cellular amine metabolic processGO:003324070.045
response to ionizing radiationGO:0010212650.045
embryonic epithelial tube formationGO:000183840.044
amine metabolic processGO:0009308440.044
regulation of cellular amino acid metabolic processGO:000652160.043
cellular macromolecule catabolic processGO:00442653800.043
positive regulation of phosphorylationGO:00423273940.042
ribonucleoside monophosphate metabolic processGO:00091611870.042
positive regulation of hydrolase activityGO:00513453310.042
epithelium developmentGO:00604292270.042
response to uvGO:0009411730.041
embryo developmentGO:00097901230.041
negative regulation of apoptotic processGO:00430663160.041
purine containing compound catabolic processGO:00725234110.040
cellular protein complex assemblyGO:00436231880.040
ribonucleoside triphosphate metabolic processGO:00091994120.040
purine nucleoside catabolic processGO:00061523980.039
base excision repairGO:0006284210.038
mitotic cell cycleGO:00002783260.037
Fly
regulation of cellular ketone metabolic processGO:0010565500.037
purine nucleotide catabolic processGO:00061954050.036
negative regulation of catalytic activityGO:00430863350.035
negative regulation of protein metabolic processGO:00512483910.035
nucleoside monophosphate catabolic processGO:00091251590.035
regulation of transferase activityGO:00513383550.035
regulation of meiotic cell cycleGO:005144540.034
cellular component disassemblyGO:0022411920.033
positive regulation of cellular amino acid metabolic processGO:004576430.032
response to abiotic stimulusGO:00096283360.032
regulation of cellular response to stressGO:00801352440.032
regulation of cellular component biogenesisGO:00440872810.031
regulation of meiosisGO:004002030.031
oxidation reduction processGO:00551143960.031
dephosphorylationGO:00163112090.030
protein catabolic processGO:00301633250.030
regulation of cellular amine metabolic processGO:0033238110.030
cellular amine metabolic processGO:0044106410.030
neuroblast proliferationGO:000740540.029
regulation of neural precursor cell proliferationGO:200017740.029
dna catabolic process exonucleolyticGO:0000738170.029
regulation of protein kinase activityGO:00458592890.028
dna catabolic process endonucleolyticGO:0000737370.028
signal transduction by phosphorylationGO:00230142970.028
gtp metabolic processGO:00460392390.028
cellular ketone metabolic processGO:0042180800.028
negative regulation of cell cycle processGO:00109481210.027
Fly
transmembrane transportGO:00550853990.027
positive regulation of nucleotide metabolic processGO:00459812300.027
regulation of mitotic cell cycleGO:00073461890.027
Fly
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.027
mapk cascadeGO:00001652880.026
single organism cellular localizationGO:19025803320.026
regulation of kinase activityGO:00435493140.026
response to oxygen containing compoundGO:19017003690.026
regulation of small gtpase mediated signal transductionGO:00510561560.026
regulation of cell cycleGO:00517263930.026
Fly
response to oxidative stressGO:00069791210.025
neuromuscular junction developmentGO:000752830.025
regulation of nucleotide metabolic processGO:00061402690.025
actin filament based processGO:00300292240.025
negative regulation of phosphorus metabolic processGO:00105632670.024
positive regulation of apoptotic processGO:00430652460.024
regulation of purine nucleotide metabolic processGO:19005422640.024
vesicle mediated transportGO:00161923710.024
chromatin organizationGO:00063253510.024
mitotic cell cycle phase transitionGO:00447721620.024
Fly
purine nucleoside monophosphate catabolic processGO:00091281580.024
protein maturationGO:00516042330.024
negative regulation of programmed cell deathGO:00430693210.024
dna synthesis involved in dna repairGO:000073160.024
small gtpase mediated signal transductionGO:0007264780.023
guanosine containing compound metabolic processGO:19010682440.023
positive regulation of nucleotide catabolic processGO:00308131850.022
locomotory behaviorGO:000762610.022
regulation of nucleoside metabolic processGO:00091182090.022
ubiquitin dependent protein catabolic processGO:00065112060.022
gtp catabolic processGO:00061842370.022
meiotic chromosome separationGO:005130730.021
regulation of protein processingGO:00706131500.021
positive regulation of programmed cell deathGO:00430682490.021
membrane organizationGO:00610242920.021
protein oligomerizationGO:00512591730.021
positive regulation of transferase activityGO:00513472270.021
mitochondrion organizationGO:00070051560.021
immune responseGO:00069553070.021
regulation of mapk cascadeGO:00434082620.020
positive regulation of cellular catabolic processGO:00313312840.020
nucleoside catabolic processGO:00091644080.020
regulation of protein transportGO:00512232130.020
rho protein signal transductionGO:0007266260.020
negative regulation of cellular protein metabolic processGO:00322693530.020
actin cytoskeleton organizationGO:00300362070.020
positive regulation of cell deathGO:00109422630.020
cell type specific apoptotic processGO:00972851250.019
golgi inheritanceGO:004831320.019
negative regulation of t cell apoptotic processGO:007023340.019
lipid metabolic processGO:00066293810.019
enzyme linked receptor protein signaling pathwayGO:00071673030.018
positive regulation of developmental processGO:00510943140.018
protein localization to organelleGO:00333652800.018
microtubule based processGO:00070172100.018
positive regulation of gtp catabolic processGO:00331261660.018
guanosine containing compound catabolic processGO:19010692390.018
system processGO:00030083490.018
g2 m transition of mitotic cell cycleGO:0000086410.018
negative regulation of phosphorylationGO:00423261740.018
cytoplasmic transportGO:00164823790.018
morphogenesis of a polarized epitheliumGO:000173830.018
negative regulation of proteolysisGO:00458611320.018
negative regulation of cell deathGO:00605483450.018
negative regulation of cell cycleGO:00457861930.018
Fly
regulation of homeostatic processGO:00328441210.017
regulation of cell migrationGO:00303342890.017
negative regulation of meiotic cell cycleGO:005144720.017
positive regulation of ras gtpase activityGO:00323201170.017
female gamete generationGO:000729220.017
tissue migrationGO:00901301190.017
mitotic cell cycle processGO:19030472860.017
Fly
primary neural tube formationGO:001402030.017
nucleoside phosphate catabolic processGO:19012924120.017
cellular lipid metabolic processGO:00442553030.017
regulation of ras protein signal transductionGO:00465781550.017
oogenesisGO:004847720.017
positive regulation of purine nucleotide catabolic processGO:00331231850.017
negative regulation of phosphate metabolic processGO:00459362670.017
response to radiationGO:00093141510.017
microtubule nucleationGO:000702060.016
neural tube closureGO:000184330.016
regulation of purine nucleotide catabolic processGO:00331212050.016
spermatid developmentGO:000728640.016
apoptotic signaling pathwayGO:00971902680.016
negative regulation of protein phosphorylationGO:00019331400.016
negative regulation of protein modification processGO:00314002000.016
nitrogen compound transportGO:00717051910.016
regulation of protein serine threonine kinase activityGO:00719001790.016
modification dependent protein catabolic processGO:00199412090.016
intracellular protein transportGO:00068862700.016
negative regulation of cell cycle phase transitionGO:1901988890.016
Fly
spermatid differentiationGO:004851540.015
chromatin modificationGO:00165682980.015
cardiovascular system developmentGO:00723582620.015
regulation of nucleotide catabolic processGO:00308112050.015
positive regulation of protein phosphorylationGO:00019343130.015
rna catabolic processGO:0006401710.015
negative regulation of cellular catabolic processGO:0031330830.015
anterior posterior axis specificationGO:000994820.015
ion transmembrane transportGO:00342203380.015
neurotransmitter secretionGO:000726940.015
negative regulation of cellular amino acid metabolic processGO:004576320.015
reciprocal dna recombinationGO:003582540.015
negative regulation of protein serine threonine kinase activityGO:0071901570.015
regulation of establishment of protein localizationGO:00702012420.015
cellular response to cytokine stimulusGO:00713451810.015
single organism membrane organizationGO:00448022680.015
cell activationGO:00017752130.015
negative regulation of catabolic processGO:00098951040.015
circulatory system developmentGO:00723592620.015
adult locomotory behaviorGO:000834410.015
lipid biosynthetic processGO:00086101770.014
negative regulation of hydrolase activityGO:00513461820.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
negative regulation of multicellular organismal processGO:00512413170.014
nerve developmentGO:002167540.014
regulation of gtpase activityGO:00430871800.014
regenerationGO:003109940.014
establishment of protein localization to organelleGO:00725941720.014
telomere maintenanceGO:0000723320.014
positive regulation of nucleoside metabolic processGO:00459791860.014
reactive oxygen species metabolic processGO:0072593750.014
regulation of gtp catabolic processGO:00331241800.014
epithelium migrationGO:00901321190.014
regulation of cellular protein catabolic processGO:1903362960.014
neural tube formationGO:000184130.014
epithelial cell differentiationGO:00308551410.014
i kappab kinase nf kappab signalingGO:00072491660.014
myosin filament assemblyGO:003103420.014
purine nucleotide biosynthetic processGO:0006164840.014
regulation of protein maturationGO:19033171500.014
hindbrain developmentGO:003090230.014
covalent chromatin modificationGO:00165692540.013
regulation of intracellular transportGO:00323861950.013
negative regulation of cell differentiationGO:00455961710.013
execution phase of apoptosisGO:0097194320.013
purine nucleoside triphosphate catabolic processGO:00091463920.013
carbohydrate derivative biosynthetic processGO:19011372070.013
cell agingGO:0007569520.013
biological adhesionGO:00226103310.013
salivary gland morphogenesisGO:000743540.013
memoryGO:000761330.013
negative regulation of protein kinase activityGO:0006469980.013
response to gamma radiationGO:0010332140.013
response to cytokineGO:00340972320.013
regulation of protein catabolic processGO:00421761550.013
posttranscriptional regulation of gene expressionGO:00106082130.013
positive regulation of protein complex assemblyGO:0031334860.013
cell morphogenesisGO:00009022960.013
actin filament based movementGO:0030048170.013
negative regulation of cellular amine metabolic processGO:003323930.013
nucleoside monophosphate metabolic processGO:00091231910.013
response to fungusGO:000962040.013
atp metabolic processGO:00460341760.013
regulation of immune effector processGO:0002697910.013
positive regulation of kinase activityGO:00336742040.013
organophosphate biosynthetic processGO:00904071630.012
nucleus localizationGO:005164710.012
negative regulation of protein processingGO:00109551420.012
negative regulation of intracellular signal transductionGO:19025321830.012
positive regulation of protein serine threonine kinase activityGO:00719021190.012
protein processingGO:00164852260.012
blastoderm segmentationGO:000735020.012
somatic stem cell divisionGO:004810310.012
regulation of response to external stimulusGO:00321012220.012
anion transportGO:00068201610.012
protein localization to membraneGO:00726571600.012
positive regulation of gtpase activityGO:00435471660.012
tissue morphogenesisGO:0048729960.012
release of cytoplasmic sequestered nf kappabGO:000858840.012
cellular component morphogenesisGO:00329893140.012
endosomal transportGO:00161971290.012
organ formationGO:004864530.012
dna recombinationGO:0006310770.012
cytokine mediated signaling pathwayGO:00192211090.012
regulation of microtubule based processGO:0032886740.012
demethylationGO:0070988370.012
sequestering of calcium ionGO:0051208170.012
regulation of protein complex assemblyGO:00432541470.012
protein targetingGO:00066051870.012
agingGO:0007568660.012
inner ear morphogenesisGO:004247240.012
regulation of growthGO:00400081650.012
regulation of response to dna damage stimulusGO:2001020940.012
positive regulation of purine nucleotide metabolic processGO:19005442270.011
positive regulation of protein kinase activityGO:00458601900.011
protein polymerizationGO:0051258710.011
mitotic nuclear divisionGO:00070671190.011
negative regulation of protein maturationGO:19033181420.011
regulation of cell differentiationGO:00455953930.011
nervous system developmentGO:00073992930.011
meiotic chromosome segregationGO:004513240.011
protein modification by small protein conjugationGO:00324463420.011
regulation of stress activated protein kinase signaling cascadeGO:0070302850.011
positive regulation of response to dna damage stimulusGO:2001022430.011
regulation of endopeptidase activityGO:00525481700.011
establishment of nucleus localizationGO:004002310.011
glycoprotein metabolic processGO:00091001100.011
negative regulation of kinase activityGO:00336731060.011
negative regulation of neural precursor cell proliferationGO:200017810.011
regulation of proteolysisGO:00301622930.011
neurological system processGO:00508771630.011
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.011
organic anion transportGO:00157111030.011
organonitrogen compound biosynthetic processGO:19015662000.011
thymocyte apoptotic processGO:007024220.011
golgi disassemblyGO:009016620.011
dna strand elongation involved in dna replicationGO:000627130.011
positive regulation of cellular component organizationGO:00511303760.011
cellular protein catabolic processGO:00442572610.011
ameboidal type cell migrationGO:00016671350.011
nucleoside triphosphate catabolic processGO:00091433940.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
cell developmentGO:00484683280.011
rhythmic behaviorGO:000762220.011
regulation of neuroblast proliferationGO:190269230.011
negative regulation of transferase activityGO:00513481240.011
semaphorin plexin signaling pathwayGO:007152640.011
endomembrane system organizationGO:00102561960.011
peripheral nervous system developmentGO:000742220.011
negative regulation of jun kinase activityGO:004350840.011
cation transportGO:00068123310.011
somatic diversification of immunoglobulins involved in immune responseGO:000220830.011
anterior posterior axis specification embryoGO:000859520.011
positive regulation of immune system processGO:00026842830.011
sensory perceptionGO:00076001030.011
negative regulation of cellular component organizationGO:00511292350.011
positive regulation of cell differentiationGO:00455972110.011
nuclear transportGO:00511691790.010
negative regulation of gliogenesisGO:001401430.010
protein ubiquitinationGO:00165673140.010
regulation of bindingGO:00510981110.010
anatomical structure formation involved in morphogenesisGO:00486462840.010
establishment of tissue polarityGO:000716430.010
stem cell divisionGO:001714520.010
reactive oxygen species biosynthetic processGO:190340940.010
protein importGO:00170381300.010
metal ion transportGO:00300012720.010
establishment of planar polarityGO:000173630.010
regulation of multi organism processGO:00439001570.010
peptidyl threonine modificationGO:0018210450.010
negative regulation of stem cell proliferationGO:200064730.010
tripartite regional subdivisionGO:000735120.010
regulation of intracellular protein transportGO:00331571230.010
syncytium formation by plasma membrane fusionGO:000076820.010
metencephalon developmentGO:002203720.010
immune effector processGO:00022521590.010
hemopoiesisGO:00300971800.010
positive regulation of cell cycle processGO:00900681060.010
positive regulation of cell proliferationGO:00082843010.010
response to woundingGO:00096111680.010

MUS81 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
bone marrow diseaseDOID:4961310.598
immune system diseaseDOID:29141550.598
hematopoietic system diseaseDOID:741000.598
anemiaDOID:2355550.382
aplastic anemiaDOID:12449300.382
congenital hypoplastic anemiaDOID:1342260.082
musculoskeletal system diseaseDOID:172230.056
xeroderma pigmentosumDOID:005042780.045
kidney diseaseDOID:557360.037
urinary system diseaseDOID:18400.037
central nervous system diseaseDOID:3311860.032
nervous system diseaseDOID:8634310.032
disease of metabolismDOID:00146672950.027
inherited metabolic disorderDOID:6552420.023
connective tissue diseaseDOID:651090.018
sensory system diseaseDOID:00501552030.017
fanconi s anemiaDOID:13636160.015
muscular diseaseDOID:00800001140.013
disease of cellular proliferationDOID:145661740.012
eye and adnexa diseaseDOID:14921500.012
neurodegenerative diseaseDOID:12891020.011
amino acid metabolic disorderDOID:9252500.010