Homo sapiens

270 known processes

PRICKLE1

prickle homolog 1 (Drosophila)

(Aliases: EPM1B,RILP,FLJ31627,MGC138903,MGC138902,FLJ31937)

PRICKLE1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.097
Fly
cellular ketone metabolic processGO:0042180800.080
cellular amino acid metabolic processGO:00065201160.077
cell developmentGO:00484683280.065
oogenesisGO:004847720.059
regulation of cellular ketone metabolic processGO:0010565500.059
female gamete generationGO:000729220.058
regulation of cellular amine metabolic processGO:0033238110.055
regulation of cellular amino acid metabolic processGO:000652160.055
multicellular organismal agingGO:001025930.055
negative regulation of multicellular organismal processGO:00512413170.055
regulation of cell differentiationGO:00455953930.055
determination of adult lifespanGO:000834020.055
nervous system developmentGO:00073992930.054
small gtpase mediated signal transductionGO:0007264780.053
epithelium developmentGO:00604292270.053
regulation of locomotionGO:00400123290.053
amine metabolic processGO:0009308440.051
response to oxygen containing compoundGO:19017003690.049
circulatory system developmentGO:00723592620.049
ras protein signal transductionGO:0007265730.048
cardiovascular system developmentGO:00723582620.048
nucleoside catabolic processGO:00091644080.047
nucleoside phosphate catabolic processGO:19012924120.047
purine ribonucleoside triphosphate metabolic processGO:00092054110.047
cellular amine metabolic processGO:0044106410.047
positive regulation of developmental processGO:00510943140.047
purine nucleotide catabolic processGO:00061954050.046
segmentationGO:003528240.046
Fly
cell projection organizationGO:00300302520.045
Zebrafish Fly
positive regulation of phosphorylationGO:00423273940.044
regulation of cellular component movementGO:00512703340.044
negative regulation of catalytic activityGO:00430863350.044
cell morphogenesisGO:00009022960.044
morphogenesis of embryonic epitheliumGO:001633140.043
nucleotide catabolic processGO:00091664080.042
purine ribonucleoside metabolic processGO:00461284370.042
actin filament based processGO:00300292240.042
negative regulation of phosphate metabolic processGO:00459362670.042
anatomical structure formation involved in morphogenesisGO:00486462840.041
purine containing compound catabolic processGO:00725234110.041
cellular component morphogenesisGO:00329893140.041
ribonucleoside catabolic processGO:00424544060.041
system processGO:00030083490.041
Human
ribonucleotide catabolic processGO:00092614050.041
locomotory behaviorGO:000762610.040
neuromuscular junction developmentGO:000752830.040
cell fate determinationGO:000170930.039
negative regulation of cellular protein metabolic processGO:00322693530.039
purine ribonucleotide catabolic processGO:00091544040.039
ribonucleoside triphosphate catabolic processGO:00092033910.039
negative regulation of phosphorus metabolic processGO:00105632670.038
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.038
organophosphate catabolic processGO:00464344300.038
negative regulation of protein metabolic processGO:00512483910.038
cell adhesionGO:00071553250.038
purine nucleoside triphosphate metabolic processGO:00091444120.037
regulation of cell migrationGO:00303342890.037
purine nucleoside catabolic processGO:00061523980.036
nucleoside triphosphate metabolic processGO:00091414220.036
positive regulation of catabolic processGO:00098963100.036
positive regulation of cellular amino acid metabolic processGO:004576430.036
glycosyl compound catabolic processGO:19016584130.036
purine ribonucleoside catabolic processGO:00461303980.035
regulation of anatomical structure morphogenesisGO:00226032860.035
protein catabolic processGO:00301633250.035
lipid metabolic processGO:00066293810.035
ribonucleoside triphosphate metabolic processGO:00091994120.034
signal transduction by phosphorylationGO:00230142970.034
regulation of transferase activityGO:00513383550.034
biological adhesionGO:00226103310.034
positive regulation of cellular catabolic processGO:00313312840.034
purine ribonucleoside triphosphate catabolic processGO:00092073910.033
regulation of cell motilityGO:20001452990.033
positive regulation of cell differentiationGO:00455972110.033
cytoplasmic transportGO:00164823790.033
positive regulation of cellular component organizationGO:00511303760.033
organ formationGO:004864530.033
vesicle mediated transportGO:00161923710.032
motor neuron axon guidanceGO:000804520.032
mapk cascadeGO:00001652880.032
positive regulation of protein phosphorylationGO:00019343130.032
positive regulation of cellular amine metabolic processGO:003324070.032
chemical homeostasisGO:00488783060.032
rho protein signal transductionGO:0007266260.032
positive regulation of transportGO:00510503360.032
generation of neuronsGO:00486991520.031
Zebrafish Fly
regulation of cellular component biogenesisGO:00440872810.031
single organism cellular localizationGO:19025803320.031
regulation of kinase activityGO:00435493140.031
regenerationGO:003109940.031
regulation of protein kinase activityGO:00458592890.030
transmembrane transportGO:00550853990.030
regulation of cell cycleGO:00517263930.030
response to abiotic stimulusGO:00096283360.030
nucleoside triphosphate catabolic processGO:00091433940.029
regulation of purine nucleotide metabolic processGO:19005422640.029
regulation of mapk cascadeGO:00434082620.029
cellular response to endogenous stimulusGO:00714953360.029
immune responseGO:00069553070.029
positive regulation of hydrolase activityGO:00513453310.028
growthGO:00400072020.028
wnt signaling pathwayGO:00160551560.028
cellular lipid metabolic processGO:00442553030.028
protein localization to organelleGO:00333652800.028
purine nucleoside triphosphate catabolic processGO:00091463920.028
ion transmembrane transportGO:00342203380.028
enzyme linked receptor protein signaling pathwayGO:00071673030.028
negative regulation of cell deathGO:00605483450.028
positive regulation of purine nucleotide metabolic processGO:19005442270.027
regulation of protein localizationGO:00328802960.027
cell morphogenesis involved in differentiationGO:00009041440.027
actin cytoskeleton organizationGO:00300362070.027
mitotic cell cycleGO:00002783260.027
Zebrafish
cation transportGO:00068123310.026
cellular response to oxygen containing compoundGO:19017012760.026
cellular macromolecule catabolic processGO:00442653800.026
positive regulation of locomotionGO:00400171860.026
regulation of nucleotide metabolic processGO:00061402690.026
cellular macromolecular complex assemblyGO:00346223240.026
negative regulation of developmental processGO:00510932470.026
organ morphogenesisGO:00098871470.026
Zebrafish Fly
chemotaxisGO:00069351570.026
memoryGO:000761330.026
non canonical wnt signaling pathway via mapk cascadeGO:003803040.026
negative regulation of programmed cell deathGO:00430693210.025
blastoderm segmentationGO:000735020.025
ameboidal type cell migrationGO:00016671350.025
Zebrafish
protein modification by small protein conjugationGO:00324463420.024
positive regulation of cell proliferationGO:00082843010.024
mitotic cell cycle processGO:19030472860.024
Zebrafish
neuron differentiationGO:00301821380.024
Zebrafish Fly
response to external biotic stimulusGO:00432072610.024
positive regulation of nucleotide metabolic processGO:00459812300.024
membrane organizationGO:00610242920.024
maintenance of locationGO:00512351120.024
carbohydrate derivative biosynthetic processGO:19011372070.024
metal ion transportGO:00300012720.024
negative regulation of cellular component organizationGO:00511292350.024
matingGO:000761810.024
regulation of purine nucleotide catabolic processGO:00331212050.024
defense responseGO:00069523150.024
negative regulation of protein modification processGO:00314002000.023
epithelial cell differentiationGO:00308551410.023
Fly
cell growthGO:00160491600.023
neurogenesisGO:00220081690.023
Zebrafish Fly
regulation of establishment of protein localizationGO:00702012420.023
negative regulation of phosphorylationGO:00423261740.023
gtp catabolic processGO:00061842370.023
response to woundingGO:00096111680.023
neural tube formationGO:000184130.023
regulation of sequence specific dna binding transcription factor activityGO:00510902110.023
positive regulation of cell migrationGO:00303351720.023
embryonic epithelial tube formationGO:000183840.023
regulation of cell growthGO:00015581350.023
single organism cell adhesionGO:00986021790.023
regulation of cellular response to stressGO:00801352440.023
gtp metabolic processGO:00460392390.023
taxisGO:00423301570.023
single organism membrane organizationGO:00448022680.023
positive regulation of mapk cascadeGO:00434101900.022
regulation of proteolysisGO:00301622930.022
inner ear morphogenesisGO:004247240.022
salivary gland morphogenesisGO:000743540.022
regulation of growthGO:00400081650.022
positive regulation of transferase activityGO:00513472270.022
cellular protein catabolic processGO:00442572610.022
response to biotic stimulusGO:00096072760.022
cellular response to dna damage stimulusGO:00069743790.022
guanosine containing compound catabolic processGO:19010692390.022
secretion by cellGO:00329402260.022
intracellular protein transportGO:00068862700.022
regulation of protein serine threonine kinase activityGO:00719001790.021
regulation of response to external stimulusGO:00321012220.021
positive regulation of nucleotide catabolic processGO:00308131850.021
proteolysis involved in cellular protein catabolic processGO:00516032440.021
regulation of cytoskeleton organizationGO:00514931770.021
positive regulation of nucleoside metabolic processGO:00459791860.021
negative regulation of hydrolase activityGO:00513461820.021
blood vessel developmentGO:00015681720.021
guanosine containing compound metabolic processGO:19010682440.021
lipid biosynthetic processGO:00086101770.021
heart formationGO:006091420.021
response to lipidGO:00339932060.020
negative regulation of cell proliferationGO:00082852280.020
Human
hindbrain developmentGO:003090230.020
Zebrafish
positive regulation of purine nucleotide catabolic processGO:00331231850.020
regulation of intracellular transportGO:00323861950.020
primary neural tube formationGO:001402030.020
regulation of actin filament based processGO:00329701410.020
specification of organ identityGO:001009230.020
inorganic ion transmembrane transportGO:00986602310.020
head developmentGO:00603221080.020
Zebrafish
inorganic cation transmembrane transportGO:00986621940.020
apoptotic signaling pathwayGO:00971902680.020
regulation of protein transportGO:00512232130.020
positive regulation of cellular component movementGO:00512721810.020
cation transmembrane transportGO:00986552380.020
anterior posterior axis specificationGO:000994820.020
Fly
dephosphorylationGO:00163112090.020
adult locomotory behaviorGO:000834410.020
epithelial cell proliferationGO:00506731280.020
immune system developmentGO:00025201950.020
epidermis morphogenesisGO:004873030.020
cytokine productionGO:00018162470.020
regulation of cell cycle processGO:00105642660.020
actin filament organizationGO:00070151280.019
regulation of nucleoside metabolic processGO:00091182090.019
ion homeostasisGO:00508012300.019
positive regulation of cell motilityGO:20001471770.019
morphogenesis of a polarized epitheliumGO:000173830.019
Fly
neurotransmitter secretionGO:000726940.019
nitrogen compound transportGO:00717051910.019
negative regulation of cell cycleGO:00457861930.019
muscle structure developmentGO:0061061980.019
peripheral nervous system developmentGO:000742220.019
microtubule cytoskeleton organizationGO:00002261760.019
Zebrafish
positive regulation of protein kinase activityGO:00458601900.019
protein ubiquitinationGO:00165673140.019
monocarboxylic acid metabolic processGO:00327871850.019
negative regulation of protein phosphorylationGO:00019331400.019
endomembrane system organizationGO:00102561960.019
regulation of small gtpase mediated signal transductionGO:00510561560.019
negative regulation of intracellular signal transductionGO:19025321830.019
nerve developmentGO:002167540.019
heart developmentGO:0007507950.019
negative regulation of cellular amine metabolic processGO:003323930.019
cellular protein complex assemblyGO:00436231880.019
positive regulation of cell deathGO:00109422630.019
protein maturationGO:00516042330.019
regulation of protein catabolic processGO:00421761550.019
cellular response to growth factor stimulusGO:00713631970.019
response to other organismGO:00517072610.019
organonitrogen compound biosynthetic processGO:19015662000.018
regulation of gtp catabolic processGO:00331241800.018
neurological system processGO:00508771630.018
central nervous system developmentGO:00074171230.018
Zebrafish
cellular homeostasisGO:00197251960.018
cell projection morphogenesisGO:00488581290.018
regulation of wnt signaling pathwayGO:00301111230.018
positive regulation of gtp catabolic processGO:00331261660.018
response to organic cyclic compoundGO:00140702040.018
cell part morphogenesisGO:00329901370.018
microtubule based processGO:00070172100.018
Zebrafish
regulation of ras protein signal transductionGO:00465781550.018
negative regulation of apoptotic processGO:00430663160.018
regulation of cytoplasmic transportGO:19036491490.018
positive regulation of gtpase activityGO:00435471660.018
actin filament based movementGO:0030048170.018
behaviorGO:00076101120.018
heart field specificationGO:000312820.018
regulation of nucleotide catabolic processGO:00308112050.018
oocyte developmentGO:004859910.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
response to growth factorGO:00708482050.018
cell cell signalingGO:00072671550.018
single organism carbohydrate metabolic processGO:00447231930.018
negative regulation of locomotionGO:00400131180.018
tube closureGO:006060630.018
proteasomal protein catabolic processGO:00104981760.018
carbohydrate metabolic processGO:00059752070.018
response to hormoneGO:00097251750.018
organelle assemblyGO:00709251760.018
secretionGO:00469032540.017
blood vessel morphogenesisGO:00485141620.017
modification dependent protein catabolic processGO:00199412090.017
embryonic morphogenesisGO:0048598850.017
cell projection assemblyGO:00300311260.017
photoreceptor cell differentiationGO:004653020.017
regulation of gtpase activityGO:00430871800.017
positive regulation of apoptotic processGO:00430652460.017
oxidation reduction processGO:00551143960.017
regulation of epithelial cell proliferationGO:00506781130.017
regulation of nervous system developmentGO:0051960880.017
neuron projection developmentGO:00311751060.017
Zebrafish
organophosphate biosynthetic processGO:00904071630.017
positive regulation of kinase activityGO:00336742040.017
protein processingGO:00164852260.017
brain developmentGO:0007420970.017
Zebrafish
muscle contractionGO:0006936730.017
regulation of synaptic plasticityGO:004816730.017
positive regulation of immune system processGO:00026842830.017
actin mediated cell contractionGO:0070252120.017
chromatin organizationGO:00063253510.017
anterior posterior axis specification embryoGO:000859520.017
regulation of cell morphogenesisGO:00226041530.017
ribonucleoside monophosphate metabolic processGO:00091611870.017
oocyte differentiationGO:000999420.017
vasculature developmentGO:00019441810.017
epithelium migrationGO:00901321190.017
cardiac muscle cell contractionGO:008600340.017
protein targetingGO:00066051870.017
positive regulation of programmed cell deathGO:00430682490.017
posttranscriptional regulation of gene expressionGO:00106082130.017
rhythmic behaviorGO:000762220.017
hemopoiesisGO:00300971800.017
spermatid differentiationGO:004851540.017
negative regulation of transferase activityGO:00513481240.017
metencephalon developmentGO:002203720.016
Zebrafish
tissue morphogenesisGO:0048729960.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
compound eye developmentGO:004874910.016
Fly
ubiquitin dependent protein catabolic processGO:00065112060.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
negative regulation of cell motilityGO:20001461040.016
canonical wnt signaling pathwayGO:00600701160.016
negative regulation of cellular component movementGO:00512711060.016
stem cell differentiationGO:0048863930.016
nucleocytoplasmic transportGO:00069131760.016
regulation of ion transportGO:00432691890.016
regulation of cytokine productionGO:00018172320.016
regulation of cell adhesionGO:00301551660.016
single organismal cell cell adhesionGO:00163371480.016
tripartite regional subdivisionGO:000735120.016
innate immune responseGO:00450871780.016
histone modificationGO:00165702510.016
modification dependent macromolecule catabolic processGO:00436322120.016
neural tube closureGO:000184330.016
regulation of ras gtpase activityGO:00323181280.016
circulatory system processGO:00030131130.016
ribonucleoside monophosphate catabolic processGO:00091581580.016
cation homeostasisGO:00550801890.016
glycoprotein metabolic processGO:00091001100.016
chromatin modificationGO:00165682980.016
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.016
covalent chromatin modificationGO:00165692540.016
embryo developmentGO:00097901230.016
hematopoietic or lymphoid organ developmentGO:00485341860.016
establishment of tissue polarityGO:000716430.016
Fly
circadian behaviorGO:004851220.016
negative regulation of transportGO:00510511760.016
regulation of homeostatic processGO:00328441210.016
positive regulation of synaptic transmissionGO:005080640.016
nucleoside monophosphate metabolic processGO:00091231910.016
establishment of planar polarityGO:000173630.016
Fly
neuron developmentGO:00486661130.016
Zebrafish Fly
protein oligomerizationGO:00512591730.016
nuclear transportGO:00511691790.016
spermatid developmentGO:000728640.016
forebrain generation of neuronsGO:002187230.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.015
small molecule biosynthetic processGO:00442831570.015
negative regulation of cell fate commitmentGO:001045430.015
reactive oxygen species biosynthetic processGO:190340940.015
cell cycle phase transitionGO:00447701730.015
response to nitrogen compoundGO:19016981840.015
neuroblast proliferationGO:000740540.015
associative learningGO:000830610.015
regulation of cell projection organizationGO:00313441070.015
regulation of actin cytoskeleton organizationGO:00329561160.015
sensory perception of painGO:001923340.015
outflow tract septum morphogenesisGO:000314840.015
multi organism cellular processGO:00447641560.015
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.015
protein localization to membraneGO:00726571600.015
regulation of mitotic cell cycleGO:00073461890.015
calcium ion transportGO:00068161470.015
regulation of membrane potentialGO:0042391950.015
sequestering of metal ionGO:0051238240.015
negative regulation of cell fate specificationGO:000999630.015
peptidyl tyrosine phosphorylationGO:00181081700.015
regulation of defense responseGO:00313471540.015
negative regulation of kinase activityGO:00336731060.015
wound healingGO:00420601150.015
retinal ganglion cell axon guidanceGO:003129020.014
limbic system developmentGO:002176130.014
regulation of cardioblast differentiationGO:005189040.014
tissue migrationGO:00901301190.014
epithelial cell migrationGO:00106311190.014
positive regulation of ras gtpase activityGO:00323201170.014
positive regulation of organelle organizationGO:00106381950.014
establishment of protein localization to organelleGO:00725941720.014
cell divisionGO:00513011680.014
divalent metal ion transportGO:00708381520.014
tissue regenerationGO:004224630.014
response to cytokineGO:00340972320.014
establishment or maintenance of apical basal cell polarityGO:003508820.014
divalent inorganic cation homeostasisGO:00725071360.014
regulation of immune responseGO:00507762010.014
cell substrate adhesionGO:00315891320.014
positive regulation of cell developmentGO:0010720920.014
axis elongationGO:000340140.014
regulation of secretionGO:00510461940.014
angiogenesisGO:00015251470.014
cell activationGO:00017752130.014
sequestering of calcium ionGO:0051208170.014
pattern specification processGO:0007389430.014
Zebrafish Fly
atp metabolic processGO:00460341760.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
regulation of cell developmentGO:00602841610.014
reproductive processGO:00224141060.014
cellular chemical homeostasisGO:00550821800.014
establishment of protein localization to membraneGO:00901501210.014
regulation of heart inductionGO:009038120.014
spinal cord developmentGO:002151040.014
viral processGO:00160321460.014
regulation of i kappab kinase nf kappab signalingGO:00431221620.014
negative regulation of growthGO:0045926970.014
endocytosisGO:00068971590.014
protein localization to nucleusGO:00345041360.014
cerebellum developmentGO:002154920.014
cranial nerve developmentGO:002154540.014
regulation of neural precursor cell proliferationGO:200017740.014
response to axon injuryGO:004867810.014
cellular cation homeostasisGO:00300031630.013
regulation of organ formationGO:000315640.013
startle responseGO:000196430.013
negative regulation of cell differentiationGO:00455961710.013
purine nucleoside monophosphate catabolic processGO:00091281580.013
atp catabolic processGO:00062001570.013
neuron projection regenerationGO:003110210.013
syncytium formation by plasma membrane fusionGO:000076820.013
reactive oxygen species metabolic processGO:0072593750.013
regulation of secretion by cellGO:19035301770.013
cellular metal ion homeostasisGO:00068751460.013
response to bacteriumGO:00096171440.013
anion transportGO:00068201610.013
stress activated protein kinase signaling cascadeGO:0031098940.013
somitogenesisGO:000175620.013
regulation of intracellular protein transportGO:00331571230.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
blood circulationGO:00080151130.013
regulation of dephosphorylationGO:0035303960.013
negative regulation of protein kinase activityGO:0006469980.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
fatty acid metabolic processGO:00066311150.013
divalent inorganic cation transportGO:00725111580.013
heart morphogenesisGO:0003007480.013
Zebrafish
negative regulation of cell growthGO:0030308830.013
nucleoside monophosphate catabolic processGO:00091251590.013
rna processingGO:00063962550.013
nucleotide biosynthetic processGO:00091651090.013
mitotic cell cycle phase transitionGO:00447721620.013
regulation of protein processingGO:00706131500.013
positive regulation of protein serine threonine kinase activityGO:00719021190.013
regulation of neurogenesisGO:0050767820.013
cellular ion homeostasisGO:00068731680.013
stem cell divisionGO:001714520.013
neural crest cell developmentGO:001403230.013
regulation of neurotransmitter secretionGO:004692830.013
cardioblast cell fate commitmentGO:004268410.013
regulation of multi organism processGO:00439001570.013
regulation of protein complex assemblyGO:00432541470.013
regulation of axon guidanceGO:190266730.013
muscle system processGO:0003012810.013
Human
regulation of bindingGO:00510981110.012
establishment or maintenance of bipolar cell polarityGO:006124520.012
i kappab kinase nf kappab signalingGO:00072491660.012
cellular response to lipidGO:00713961270.012
response to radiationGO:00093141510.012
regulation of protein maturationGO:19033171500.012
g protein coupled receptor signaling pathwayGO:00071862070.012
thymus developmentGO:004853830.012
response to organonitrogen compoundGO:00102431560.012
negative regulation of cell migrationGO:00303361020.012
glycoprotein biosynthetic processGO:0009101910.012
organic hydroxy compound metabolic processGO:19016151470.012
cellular divalent inorganic cation homeostasisGO:00725031280.012
positive regulation of proteolysisGO:00458621420.012
reactive nitrogen species metabolic processGO:200105730.012
regulation of stress activated mapk cascadeGO:0032872840.012
negative regulation of organelle organizationGO:00106391260.012
interspecies interaction between organismsGO:00444191560.012
regulation of peptidase activityGO:00525471800.012
release of cytoplasmic sequestered nf kappabGO:000858840.012
regulation of canonical wnt signaling pathwayGO:0060828880.012
regulation of nucleocytoplasmic transportGO:0046822980.012
protein autophosphorylationGO:00467771230.012
monovalent inorganic cation transportGO:00156721280.012
peptidyl tyrosine modificationGO:00182121700.012
mitochondrion organizationGO:00070051560.012
single organism reproductive processGO:0044702980.012
rna interferenceGO:001624640.012

PRICKLE1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.035
disease of metabolismDOID:00146672950.026
nervous system diseaseDOID:8634310.023
sensory system diseaseDOID:00501552030.023
eye and adnexa diseaseDOID:14921500.022
eye diseaseDOID:56141490.022
connective tissue diseaseDOID:651090.020
central nervous system diseaseDOID:3311860.019
disease of cellular proliferationDOID:145661740.017
cancerDOID:1621670.017
organ system cancerDOID:00506861640.017
cardiovascular system diseaseDOID:12871060.017
inherited metabolic disorderDOID:6552420.017
bone diseaseDOID:0080001880.016
retinal diseaseDOID:56791180.015
muscle tissue diseaseDOID:661130.013
muscular diseaseDOID:00800001140.013
immune system diseaseDOID:29141550.012
bone development diseaseDOID:0080006550.012