Homo sapiens

236 known processes

CYP27B1

cytochrome P450, family 27, subfamily B, polypeptide 1

(Aliases: P450c1,VDR,CYP27B,CP2B,VDDR,CYP1alpha,VDD1,VDDRI,PDDR,CYP1)

CYP27B1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.094
cellular amine metabolic processGO:0044106410.092
amine metabolic processGO:0009308440.088
positive regulation of cellular amino acid metabolic processGO:004576430.085
positive regulation of cellular amine metabolic processGO:003324070.081
negative regulation of cell proliferationGO:00082852280.072
regulation of cellular amino acid metabolic processGO:000652160.069
post embryonic developmentGO:000979120.067
Fly
regulation of cellular amine metabolic processGO:0033238110.067
cellular ketone metabolic processGO:0042180800.066
Human Fly
detection of chemical stimulus involved in sensory perception of smellGO:005091120.064
regulation of cellular ketone metabolic processGO:0010565500.063
response to oxygen containing compoundGO:19017003690.063
lipid metabolic processGO:00066293810.057
response to organic cyclic compoundGO:00140702040.057
biological adhesionGO:00226103310.056
regulation of cell differentiationGO:00455953930.055
positive regulation of transportGO:00510503360.054
response to abiotic stimulusGO:00096283360.052
positive regulation of cell proliferationGO:00082843010.051
defense responseGO:00069523150.050
transmembrane transportGO:00550853990.050
regulation of cell cycleGO:00517263930.046
system processGO:00030083490.045
Human
ion transmembrane transportGO:00342203380.045
circulatory system developmentGO:00723592620.045
regulation of protein localizationGO:00328802960.044
positive regulation of cellular component organizationGO:00511303760.044
cellular response to endogenous stimulusGO:00714953360.044
Human
cation transportGO:00068123310.044
positive regulation of phosphorylationGO:00423273940.042
chemical homeostasisGO:00488783060.042
negative regulation of multicellular organismal processGO:00512413170.042
regulation of cellular component movementGO:00512703340.041
cell adhesionGO:00071553250.041
regulation of cytokine productionGO:00018172320.041
cellular lipid metabolic processGO:00442553030.040
secretion by cellGO:00329402260.040
response to lipidGO:00339932060.040
cellular response to oxygen containing compoundGO:19017012760.039
segmentationGO:003528240.039
regulation of cell migrationGO:00303342890.039
secretionGO:00469032540.039
regulation of cell motilityGO:20001452990.038
immune responseGO:00069553070.038
female gamete generationGO:000729220.038
anatomical structure formation involved in morphogenesisGO:00486462840.038
response to other organismGO:00517072610.037
oogenesisGO:004847720.037
negative regulation of cellular protein metabolic processGO:00322693530.037
positive regulation of immune system processGO:00026842830.037
metal ion transportGO:00300012720.037
regulation of transferase activityGO:00513383550.037
negative regulation of protein metabolic processGO:00512483910.036
regulation of secretion by cellGO:19035301770.036
negative regulation of apoptotic processGO:00430663160.036
cation transmembrane transportGO:00986552380.036
cytoplasmic transportGO:00164823790.035
anion transportGO:00068201610.035
regulation of kinase activityGO:00435493140.035
reactive oxygen species metabolic processGO:0072593750.034
determination of adult lifespanGO:000834020.034
small molecule biosynthetic processGO:00442831570.034
locomotory behaviorGO:000762610.034
organonitrogen compound biosynthetic processGO:19015662000.034
regulation of secretionGO:00510461940.034
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.034
response to hormoneGO:00097251750.034
multicellular organismal agingGO:001025930.034
regulation of hormone levelsGO:00108171250.033
Human Fly
positive regulation of protein phosphorylationGO:00019343130.033
regenerationGO:003109940.033
regulation of establishment of protein localizationGO:00702012420.033
response to external biotic stimulusGO:00432072610.033
cell morphogenesisGO:00009022960.033
Fly
cytokine productionGO:00018162470.033
regulation of protein kinase activityGO:00458592890.032
cellular response to cytokine stimulusGO:00713451810.032
regulation of anatomical structure morphogenesisGO:00226032860.032
positive regulation of hydrolase activityGO:00513453310.032
oxidation reduction processGO:00551143960.032
cellular macromolecule catabolic processGO:00442653800.032
regulation of locomotionGO:00400123290.031
response to cytokineGO:00340972320.031
alcohol metabolic processGO:00060661140.031
negative regulation of cell deathGO:00605483450.031
negative regulation of catalytic activityGO:00430863350.031
regulation of protein transportGO:00512232130.031
positive regulation of apoptotic processGO:00430652460.031
positive regulation of cytokine productionGO:00018191670.030
positive regulation of developmental processGO:00510943140.030
cardiac muscle cell contractionGO:008600340.030
negative regulation of phosphate metabolic processGO:00459362670.030
blood vessel developmentGO:00015681720.030
carbohydrate derivative biosynthetic processGO:19011372070.030
epithelium developmentGO:00604292270.029
protein catabolic processGO:00301633250.029
reactive oxygen species biosynthetic processGO:190340940.029
cellular component morphogenesisGO:00329893140.029
Fly
nitrogen compound transportGO:00717051910.029
nervous system developmentGO:00073992930.028
Fly
response to biotic stimulusGO:00096072760.028
positive regulation of programmed cell deathGO:00430682490.028
negative regulation of programmed cell deathGO:00430693210.028
organ formationGO:004864530.028
mitotic cell cycleGO:00002783260.027
organ morphogenesisGO:00098871470.027
regulation of sequence specific dna binding transcription factor activityGO:00510902110.027
enzyme linked receptor protein signaling pathwayGO:00071673030.027
apoptotic signaling pathwayGO:00971902680.027
regulation of reactive oxygen species metabolic processGO:2000377410.027
ras protein signal transductionGO:0007265730.027
hindbrain developmentGO:003090230.027
protein localization to organelleGO:00333652800.026
regulation of proteolysisGO:00301622930.026
cellular response to dna damage stimulusGO:00069743790.026
neuromuscular junction developmentGO:000752830.026
cellular homeostasisGO:00197251960.026
single organism cellular localizationGO:19025803320.026
carbohydrate metabolic processGO:00059752070.026
inorganic ion transmembrane transportGO:00986602310.026
small gtpase mediated signal transductionGO:0007264780.026
monovalent inorganic cation transportGO:00156721280.026
negative regulation of phosphorus metabolic processGO:00105632670.026
epithelial cell proliferationGO:00506731280.026
single organism carbohydrate metabolic processGO:00447231930.025
actin filament based processGO:00300292240.025
cell activationGO:00017752130.025
ion homeostasisGO:00508012300.025
innate immune responseGO:00450871780.025
anterior posterior axis specificationGO:000994820.025
regulation of cellular component biogenesisGO:00440872810.025
vesicle mediated transportGO:00161923710.025
positive regulation of transferase activityGO:00513472270.024
positive regulation of cell migrationGO:00303351720.024
lipid biosynthetic processGO:00086101770.024
cardiovascular system developmentGO:00723582620.024
regulation of reactive oxygen species biosynthetic processGO:190342630.024
vasculature developmentGO:00019441810.024
purine ribonucleoside metabolic processGO:00461284370.024
mapk cascadeGO:00001652880.024
positive regulation of cell deathGO:00109422630.024
regulation of mitotic cell cycleGO:00073461890.024
protein maturationGO:00516042330.024
response to nitrogen compoundGO:19016981840.024
membrane organizationGO:00610242920.024
reactive nitrogen species metabolic processGO:200105730.023
dephosphorylationGO:00163112090.023
inorganic cation transmembrane transportGO:00986621940.023
positive regulation of secretion by cellGO:19035321080.023
regulation of cell adhesionGO:00301551660.023
mitotic cell cycle processGO:19030472860.023
epidermis morphogenesisGO:004873030.023
blastoderm segmentationGO:000735020.023
morphogenesis of embryonic epitheliumGO:001633140.023
Fly
actin mediated cell contractionGO:0070252120.023
regulation of cell cycle processGO:00105642660.023
sensory perception of painGO:001923340.023
cell projection organizationGO:00300302520.023
Fly
cell developmentGO:00484683280.022
Fly
positive regulation of cell differentiationGO:00455972110.022
immune system developmentGO:00025201950.022
response to organonitrogen compoundGO:00102431560.022
protein oligomerizationGO:00512591730.022
nerve developmentGO:002167540.022
growthGO:00400072020.022
regulation of apoptotic signaling pathwayGO:20012331750.022
maintenance of locationGO:00512351120.022
positive regulation of protein transportGO:00512221350.022
inner ear morphogenesisGO:004247240.022
organic hydroxy compound metabolic processGO:19016151470.022
regulation of ion transportGO:00432691890.022
regulation of response to external stimulusGO:00321012220.022
hematopoietic or lymphoid organ developmentGO:00485341860.021
actin filament based movementGO:0030048170.021
negative regulation of developmental processGO:00510932470.021
glial cell migrationGO:000834740.021
nucleoside triphosphate metabolic processGO:00091414220.021
cellular response to organic cyclic compoundGO:00714071270.021
specification of organ identityGO:001009230.021
positive regulation of kinase activityGO:00336742040.021
single organism cell adhesionGO:00986021790.021
oocyte differentiationGO:000999420.021
single organismal cell cell adhesionGO:00163371480.021
negative regulation of cell cycleGO:00457861930.021
negative regulation of transportGO:00510511760.021
single organism membrane organizationGO:00448022680.021
purine nucleoside triphosphate metabolic processGO:00091444120.021
motor neuron axon guidanceGO:000804520.021
Fly
embryonic epithelial tube formationGO:000183840.021
adult locomotory behaviorGO:000834410.021
positive regulation of cell motilityGO:20001471770.021
response to metal ionGO:0010038840.020
Human
cell fate determinationGO:000170930.020
positive regulation of locomotionGO:00400171860.020
multi organism cellular processGO:00447641560.020
oocyte developmentGO:004859910.020
purine ribonucleoside triphosphate catabolic processGO:00092073910.020
rho protein signal transductionGO:0007266260.020
blood vessel morphogenesisGO:00485141620.020
positive regulation of cellular catabolic processGO:00313312840.020
chromatin organizationGO:00063253510.020
cranial nerve developmentGO:002154540.020
memoryGO:000761330.020
covalent chromatin modificationGO:00165692540.020
symbiosis encompassing mutualism through parasitismGO:00444031560.020
cellular chemical homeostasisGO:00550821800.020
hemopoiesisGO:00300971800.020
cation homeostasisGO:00550801890.020
protein processingGO:00164852260.020
signal transduction by phosphorylationGO:00230142970.020
negative regulation of cellular component organizationGO:00511292350.020
organic anion transportGO:00157111030.020
ribonucleoside triphosphate catabolic processGO:00092033910.020
regulation of peptidase activityGO:00525471800.019
divalent inorganic cation homeostasisGO:00725071360.019
posttranscriptional regulation of gene expressionGO:00106082130.019
positive regulation of catabolic processGO:00098963100.019
purine nucleotide catabolic processGO:00061954050.019
ribonucleotide catabolic processGO:00092614050.019
positive regulation of protein kinase activityGO:00458601900.019
ribonucleoside catabolic processGO:00424544060.019
positive regulation of mapk cascadeGO:00434101900.019
cellular response to lipidGO:00713961270.019
catagenGO:004263730.019
protein targetingGO:00066051870.019
cellular protein catabolic processGO:00442572610.019
positive regulation of secretionGO:00510471160.019
response to inorganic substanceGO:00100351270.019
Human
purine ribonucleoside triphosphate metabolic processGO:00092054110.019
cell divisionGO:00513011680.019
negative regulation of cellular amine metabolic processGO:003323930.019
ribonucleoside triphosphate metabolic processGO:00091994120.019
nucleoside triphosphate catabolic processGO:00091433940.019
regulation of endopeptidase activityGO:00525481700.019
cellular response to growth factor stimulusGO:00713631970.019
regulation of cellular response to stressGO:00801352440.019
purine ribonucleotide catabolic processGO:00091544040.019
positive regulation of keratinocyte migrationGO:005154940.019
cellular macromolecular complex assemblyGO:00346223240.019
negative regulation of reactive oxygen species metabolic processGO:2000378110.019
nucleoside phosphate catabolic processGO:19012924120.019
negative regulation of protein modification processGO:00314002000.019
organic acid biosynthetic processGO:0016053970.019
photoreceptor cell differentiationGO:004653020.018
chromatin modificationGO:00165682980.018
interspecies interaction between organismsGO:00444191560.018
histone modificationGO:00165702510.018
embryo developmentGO:00097901230.018
Fly
response to bacteriumGO:00096171440.018
cellular metal ion homeostasisGO:00068751460.018
response to woundingGO:00096111680.018
organophosphate catabolic processGO:00464344300.018
purine ribonucleoside catabolic processGO:00461303980.018
protein secretionGO:0009306980.018
immune effector processGO:00022521590.018
negative regulation of cytokine productionGO:0001818820.018
response to radiationGO:00093141510.018
positive regulation of organelle organizationGO:00106381950.018
lipid localizationGO:00108761060.018
tissue regenerationGO:004224630.018
tissue migrationGO:00901301190.018
viral processGO:00160321460.018
nucleotide catabolic processGO:00091664080.018
purine containing compound catabolic processGO:00725234110.018
negative regulation of cell differentiationGO:00455961710.018
positive regulation of reactive oxygen species biosynthetic processGO:190342820.018
regulation of protein complex assemblyGO:00432541470.018
positive regulation of cellular component biogenesisGO:00440891580.018
regulation of transmembrane transportGO:00347621390.017
hair follicle morphogenesisGO:003106920.017
protein ubiquitinationGO:00165673140.017
intracellular protein transportGO:00068862700.017
neuroblast proliferationGO:000740540.017
organophosphate biosynthetic processGO:00904071630.017
regulation of mapk cascadeGO:00434082620.017
angiogenesisGO:00015251470.017
positive regulation of cellular component movementGO:00512721810.017
regulation of protein secretionGO:0050708860.017
regulation of immune responseGO:00507762010.017
cellular ion homeostasisGO:00068731680.017
tripartite regional subdivisionGO:000735120.017
regulation of cell activationGO:00508651250.017
response to steroid hormoneGO:0048545800.017
establishment of protein localization to organelleGO:00725941720.017
peripheral nervous system developmentGO:000742220.017
anterior posterior axis specification embryoGO:000859520.017
regulation of protein catabolic processGO:00421761550.017
cell cell signalingGO:00072671550.017
carboxylic acid biosynthetic processGO:0046394970.017
protein localization to nucleusGO:00345041360.017
nuclear transportGO:00511691790.017
compound eye developmentGO:004874910.017
fatty acid metabolic processGO:00066311150.017
regulation of bindingGO:00510981110.017
regulation of epithelial cell proliferationGO:00506781130.017
muscle contractionGO:0006936730.017
purine nucleoside triphosphate catabolic processGO:00091463920.016
circadian behaviorGO:004851220.016
i kappab kinase nf kappab signalingGO:00072491660.016
regulation of intracellular transportGO:00323861950.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
g protein coupled receptor signaling pathwayGO:00071862070.016
regulation of protein serine threonine kinase activityGO:00719001790.016
negative regulation of immune system processGO:00026831360.016
neurological system processGO:00508771630.016
negative regulation of hydrolase activityGO:00513461820.016
peptidyl tyrosine phosphorylationGO:00181081700.016
negative regulation of phosphorylationGO:00423261740.016
negative regulation of intracellular signal transductionGO:19025321830.016
associative learningGO:000830610.016
reproductive processGO:00224141060.016
nucleocytoplasmic transportGO:00069131760.016
rna processingGO:00063962550.016
viral life cycleGO:00190581320.016
ameboidal type cell migrationGO:00016671350.016
syncytium formation by plasma membrane fusionGO:000076820.016
response to growth factorGO:00708482050.016
spermatid differentiationGO:004851540.016
endomembrane system organizationGO:00102561960.016
positive regulation of cell cycleGO:00457871400.016
epithelial cell migrationGO:00106311190.016
carboxylic acid transportGO:0046942630.016
regulation of multi organism processGO:00439001570.016
salivary gland morphogenesisGO:000743540.016
leukocyte activationGO:00453211640.016
purine nucleoside catabolic processGO:00061523980.016
regulation of purine nucleotide metabolic processGO:19005422640.015
regulation of synaptic plasticityGO:004816730.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
striated muscle contractionGO:0006941520.015
muscle system processGO:0003012810.015
neurogenesisGO:00220081690.015
Fly
glycosyl compound catabolic processGO:19016584130.015
methylationGO:00322591060.015
sensory perception of smellGO:000760820.015
monocarboxylic acid metabolic processGO:00327871850.015
metencephalon developmentGO:002203720.015
positive regulation of proteolysisGO:00458621420.015
macromolecule methylationGO:0043414970.015
nucleoside catabolic processGO:00091644080.015
cellular cation homeostasisGO:00300031630.015
cellular divalent inorganic cation homeostasisGO:00725031280.015
somitogenesisGO:000175620.015
spinal cord developmentGO:002151040.015
regulation of cysteine type endopeptidase activityGO:20001161270.015
positive regulation of protein complex assemblyGO:0031334860.015
developmental programmed cell deathGO:001062330.015
rhythmic behaviorGO:000762220.015
single organism reproductive processGO:0044702980.015
kidney developmentGO:0001822530.015
cardiac muscle contractionGO:0060048340.015
limbic system developmentGO:002176130.015
gtp catabolic processGO:00061842370.015
response to extracellular stimulusGO:0009991850.015
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.015
positive regulation of nucleotide metabolic processGO:00459812300.015
mitochondrion organizationGO:00070051560.015
tube developmentGO:00352951250.015
Fly
somatic stem cell maintenanceGO:003501940.015
embryonic camera type eye developmentGO:003107620.015
regulation of keratinocyte migrationGO:005154740.014
regulation of i kappab kinase nf kappab signalingGO:00431221620.014
response to fungusGO:000962040.014
lipid catabolic processGO:0016042840.014
tissue morphogenesisGO:0048729960.014
Fly
positive regulation of large conductance calcium activated potassium channel activityGO:190260820.014
negative regulation of protein processingGO:00109551420.014
divalent inorganic cation transportGO:00725111580.014
response to axon injuryGO:004867810.014
thymus developmentGO:004853830.014
response to virusGO:00096151260.014
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.014
regulation of lymphocyte activationGO:00512491030.014
divalent metal ion transportGO:00708381520.014
release of cytoplasmic sequestered nf kappabGO:000858840.014
lipid transportGO:0006869900.014
myoblast fusionGO:000752010.014
cellular response to hormone stimulusGO:00328701250.014
Human
taxisGO:00423301570.014
Fly
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.014
head developmentGO:00603221080.014
cell morphogenesis involved in differentiationGO:00009041440.014
Fly
regulation of cell growthGO:00015581350.014
spermatid developmentGO:000728640.014
extrinsic apoptotic signaling pathwayGO:00971911190.014
positive regulation of reactive oxygen species metabolic processGO:2000379240.014
regulation of peptidyl tyrosine phosphorylationGO:00507301080.014
negative regulation of proteolysisGO:00458611320.014
protein modification by small protein conjugationGO:00324463420.014
renal system developmentGO:0072001630.014
hormone metabolic processGO:0042445610.014
Human Fly
regulation of leukocyte activationGO:00026941150.014
visual behaviorGO:000763220.014
response to drugGO:0042493810.014
guanosine containing compound catabolic processGO:19010692390.014
positive regulation of purine nucleotide metabolic processGO:19005442270.014
sequestering of metal ionGO:0051238240.014
response to oxygen levelsGO:00704821000.014
dna repairGO:00062811980.014
regulation of cell divisionGO:00513021160.014
cellular response to organonitrogen compoundGO:00714171240.014
cellular calcium ion homeostasisGO:00068741170.014
protein localization to membraneGO:00726571600.014
gtp metabolic processGO:00460392390.013
regulation of protein maturationGO:19033171500.013
cd8 positive alpha beta t cell activationGO:003603730.013
tube morphogenesisGO:0035239950.013
regulation of neural precursor cell proliferationGO:200017740.013
wound healingGO:00420601150.013
organic hydroxy compound biosynthetic processGO:1901617710.013
positive regulation of synaptic transmissionGO:005080640.013
regulation of membrane potentialGO:0042391950.013
central nervous system developmentGO:00074171230.013
Fly
negative regulation of catabolic processGO:00098951040.013
cellular protein complex assemblyGO:00436231880.013
regulation of nucleotide metabolic processGO:00061402690.013
hormone transportGO:0009914680.013
anatomical structure homeostasisGO:00602491000.013
midgut developmentGO:000749410.013
Fly
keratinizationGO:003142420.013
response to oxidative stressGO:00069791210.013
single organism nuclear importGO:19025931040.013
cellular response to abiotic stimulusGO:00712141170.013
regulation of system processGO:00440571010.013
regulation of metal ion transportGO:00109591200.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.013
cell growthGO:00160491600.013
glycoprotein metabolic processGO:00091001100.013
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.013
epithelium migrationGO:00901321190.013
organelle fissionGO:00482851490.013
regulation of meiotic cell cycleGO:005144540.013
regulation of dna metabolic processGO:00510521530.013
epithelial cell differentiationGO:00308551410.013
cell part morphogenesisGO:00329901370.013
Fly
cell type specific apoptotic processGO:00972851250.013
positive regulation of nucleoside metabolic processGO:00459791860.013
response to alcoholGO:0097305640.013
leukocyte migrationGO:00509001070.013
response to hypoxiaGO:0001666960.013
morphogenesis of a polarized epitheliumGO:000173830.013
modification dependent macromolecule catabolic processGO:00436322120.013
cell cycle phase transitionGO:00447701730.013
modification dependent protein catabolic processGO:00199412090.013
brain developmentGO:0007420970.013
embryonic forelimb morphogenesisGO:003511540.013
proteasomal protein catabolic processGO:00104981760.013
chemotaxisGO:00069351570.013
Fly
wnt signaling pathwayGO:00160551560.013
regulation of cell morphogenesisGO:00226041530.013
positive regulation of monocyte chemotactic protein 1 productionGO:007163930.013
circulatory system processGO:00030131130.013
Human
negative regulation of protein maturationGO:19033181420.013
nuclear importGO:00511701060.013
forelimb morphogenesisGO:003513640.013
t cell differentiation in thymusGO:003307740.013
tissue homeostasisGO:0001894630.013
mitotic nuclear divisionGO:00070671190.013
peptidyl tyrosine modificationGO:00182121700.013
regulation of ion transmembrane transportGO:00347651320.013
regulation of protein processingGO:00706131500.013
negative regulation of protein phosphorylationGO:00019331400.013
organelle assemblyGO:00709251760.012
negative regulation of apoptotic signaling pathwayGO:2001234970.012
regulation of intracellular protein transportGO:00331571230.012
regulation of hormone secretionGO:0046883570.012
multicellular organismal homeostasisGO:0048871670.012
regulation of response to woundingGO:19030341010.012
neuron fate commitmentGO:004866320.012
lung alveolus developmentGO:004828640.012
myeloid cell differentiationGO:00300991170.012
myeloid leukocyte differentiationGO:0002573600.012
embryonic viscerocranium morphogenesisGO:004870310.012
cellular response to nitrogen compoundGO:19016991440.012
cerebellum developmentGO:002154920.012
organic hydroxy compound transportGO:0015850630.012

CYP27B1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.039
nervous system diseaseDOID:8634310.039
disease of metabolismDOID:00146672950.031
Human
inherited metabolic disorderDOID:6552420.027
Human
disease of cellular proliferationDOID:145661740.023
cancerDOID:1621670.022
eye diseaseDOID:56141490.022
eye and adnexa diseaseDOID:14921500.022
musculoskeletal system diseaseDOID:172230.021
connective tissue diseaseDOID:651090.021
bone diseaseDOID:0080001880.021
organ system cancerDOID:00506861640.021
central nervous system diseaseDOID:3311860.020
retinal diseaseDOID:56791180.016
kidney diseaseDOID:557360.013
urinary system diseaseDOID:18400.013