Homo sapiens

96 known processes

PPM1E

protein phosphatase, Mg2+/Mn2+ dependent, 1E

(Aliases: POPX1,CaMKP-N,DKFZp781F1422,KIAA1072,PP2CH)

PPM1E biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.094
system processGO:00030083490.084
regulation of cellular ketone metabolic processGO:0010565500.084
nervous system developmentGO:00073992930.081
locomotory behaviorGO:000762610.068
positive regulation of developmental processGO:00510943140.067
cellular component morphogenesisGO:00329893140.060
cell projection organizationGO:00300302520.060
multicellular organismal agingGO:001025930.057
regulation of cellular amino acid metabolic processGO:000652160.057
cell morphogenesisGO:00009022960.056
positive regulation of catabolic processGO:00098963100.056
ion transmembrane transportGO:00342203380.054
ion homeostasisGO:00508012300.054
determination of adult lifespanGO:000834020.053
negative regulation of protein metabolic processGO:00512483910.053
cellular amino acid metabolic processGO:00065201160.052
cellular amine metabolic processGO:0044106410.051
regulation of acrosome reactionGO:006004640.051
ribonucleoside catabolic processGO:00424544060.048
positive regulation of transportGO:00510503360.047
cellular ketone metabolic processGO:0042180800.047
amine metabolic processGO:0009308440.046
cell developmentGO:00484683280.046
lipid metabolic processGO:00066293810.046
vesicle mediated transportGO:00161923710.045
transmembrane transportGO:00550853990.044
regulation of cellular amine metabolic processGO:0033238110.044
chromatin organizationGO:00063253510.043
establishment or maintenance of apical basal cell polarityGO:003508820.043
neuron differentiationGO:00301821380.042
purine ribonucleoside catabolic processGO:00461303980.042
purine ribonucleoside metabolic processGO:00461284370.042
cation transportGO:00068123310.041
nucleoside triphosphate catabolic processGO:00091433940.040
positive regulation of acrosome reactionGO:200034440.040
regulation of cell differentiationGO:00455953930.039
negative regulation of cellular protein metabolic processGO:00322693530.039
female gamete generationGO:000729220.039
organophosphate catabolic processGO:00464344300.039
secretion by cellGO:00329402260.039
biological adhesionGO:00226103310.039
Human
glycosyl compound catabolic processGO:19016584130.039
generation of neuronsGO:00486991520.038
cell adhesionGO:00071553250.038
Human
regulation of synaptic plasticityGO:004816730.038
segmentationGO:003528240.038
purine containing compound catabolic processGO:00725234110.038
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.038
positive regulation of cellular amino acid metabolic processGO:004576430.037
neuroblast proliferationGO:000740540.037
positive regulation of cellular catabolic processGO:00313312840.037
chemical homeostasisGO:00488783060.037
purine ribonucleoside triphosphate catabolic processGO:00092073910.037
purine nucleotide catabolic processGO:00061954050.037
positive regulation of cellular amine metabolic processGO:003324070.037
chromatin modificationGO:00165682980.036
memoryGO:000761330.036
negative regulation of transmission of nerve impulseGO:005197010.036
oogenesisGO:004847720.036
purine ribonucleotide catabolic processGO:00091544040.036
neurogenesisGO:00220081690.035
regulation of meiotic cell cycleGO:005144540.035
ribonucleoside triphosphate catabolic processGO:00092033910.035
cation transmembrane transportGO:00986552380.035
regulation of secretion by cellGO:19035301770.034
inorganic ion transmembrane transportGO:00986602310.034
nucleoside catabolic processGO:00091644080.034
inorganic cation transmembrane transportGO:00986621940.034
ras protein signal transductionGO:0007265730.034
hindbrain developmentGO:003090230.034
neuron projection developmentGO:00311751060.034
negative regulation of cell deathGO:00605483450.033
negative regulation of catalytic activityGO:00430863350.033
purine ribonucleoside triphosphate metabolic processGO:00092054110.033
metal ion transportGO:00300012720.033
organonitrogen compound biosynthetic processGO:19015662000.033
actin filament based processGO:00300292240.032
histone modificationGO:00165702510.032
positive regulation of synaptic transmissionGO:005080640.032
single organism membrane organizationGO:00448022680.032
regulation of proteolysisGO:00301622930.032
Human
ribonucleoside triphosphate metabolic processGO:00091994120.032
regulation of protein localizationGO:00328802960.032
purine nucleoside catabolic processGO:00061523980.032
small gtpase mediated signal transductionGO:0007264780.032
membrane organizationGO:00610242920.031
nucleotide catabolic processGO:00091664080.031
nucleoside phosphate catabolic processGO:19012924120.031
purine nucleoside triphosphate metabolic processGO:00091444120.031
negative regulation of programmed cell deathGO:00430693210.031
establishment or maintenance of bipolar cell polarityGO:006124520.031
positive regulation of phosphorylationGO:00423273940.031
gtp catabolic processGO:00061842370.030
regulation of cell cycleGO:00517263930.030
nucleoside triphosphate metabolic processGO:00091414220.030
protein catabolic processGO:00301633250.030
carbohydrate derivative biosynthetic processGO:19011372070.030
regulation of purine nucleotide metabolic processGO:19005422640.030
response to abiotic stimulusGO:00096283360.030
nerve developmentGO:002167540.030
mitotic cell cycleGO:00002783260.030
neuromuscular junction developmentGO:000752830.030
carbohydrate metabolic processGO:00059752070.030
cytoplasmic transportGO:00164823790.030
positive regulation of secretionGO:00510471160.029
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.029
regulation of establishment of protein localizationGO:00702012420.029
negative regulation of phosphorus metabolic processGO:00105632670.029
secretionGO:00469032540.029
regulation of cellular component movementGO:00512703340.029
Human
cellular macromolecular complex assemblyGO:00346223240.028
purine nucleoside triphosphate catabolic processGO:00091463920.028
ribonucleotide catabolic processGO:00092614050.028
regulation of nucleotide metabolic processGO:00061402690.028
negative regulation of apoptotic processGO:00430663160.028
single organism cellular localizationGO:19025803320.028
negative regulation of phosphate metabolic processGO:00459362670.028
growthGO:00400072020.027
Human
nitrogen compound transportGO:00717051910.027
guanosine containing compound catabolic processGO:19010692390.027
regulation of secretionGO:00510461940.027
regulation of protein kinase activityGO:00458592890.027
maintenance of locationGO:00512351120.027
lipid biosynthetic processGO:00086101770.027
cellular macromolecule catabolic processGO:00442653800.027
covalent chromatin modificationGO:00165692540.027
regenerationGO:003109940.027
monocarboxylic acid metabolic processGO:00327871850.027
neuron developmentGO:00486661130.026
negative regulation of intracellular signal transductionGO:19025321830.026
response to oxygen containing compoundGO:19017003690.026
single organism carbohydrate metabolic processGO:00447231930.026
associative learningGO:000830610.026
protein oligomerizationGO:00512591730.026
protein modification by small protein conjugationGO:00324463420.025
metencephalon developmentGO:002203720.025
anatomical structure formation involved in morphogenesisGO:00486462840.025
neurotransmitter secretionGO:000726940.025
positive regulation of cellular component organizationGO:00511303760.025
cellular protein catabolic processGO:00442572610.025
morphogenesis of embryonic epitheliumGO:001633140.025
positive regulation of hydrolase activityGO:00513453310.025
Human
guanosine containing compound metabolic processGO:19010682440.025
cellular response to endogenous stimulusGO:00714953360.025
regulation of hormone levelsGO:00108171250.025
negative regulation of cellular component organizationGO:00511292350.025
motor neuron axon guidanceGO:000804520.025
positive regulation of purine nucleotide metabolic processGO:19005442270.024
cellular response to oxygen containing compoundGO:19017012760.024
cellular lipid metabolic processGO:00442553030.024
cellular response to histamineGO:007142030.024
regulation of neural precursor cell proliferationGO:200017740.024
startle responseGO:000196430.024
positive regulation of cell differentiationGO:00455972110.024
blastoderm segmentationGO:000735020.024
regulation of cell growthGO:00015581350.024
cell growthGO:00160491600.024
positive regulation of protein phosphorylationGO:00019343130.024
cell cell signalingGO:00072671550.024
positive regulation of secretion by cellGO:19035321080.024
protein ubiquitinationGO:00165673140.024
response to organic cyclic compoundGO:00140702040.024
response to activityGO:001482300.024
anterior posterior axis specificationGO:000994820.024
regulation of nucleoside metabolic processGO:00091182090.024
adult locomotory behaviorGO:000834410.024
neurological system processGO:00508771630.024
limbic system developmentGO:002176130.024
regulation of transmission of nerve impulseGO:005196920.023
regulation of growthGO:00400081650.023
Human
cell projection morphogenesisGO:00488581290.023
positive regulation of cell proliferationGO:00082843010.023
negative regulation of cell cycleGO:00457861930.023
cardiac muscle cell contractionGO:008600340.023
gamma aminobutyric acid signaling pathwayGO:000721430.023
cell fate determinationGO:000170930.023
photoreceptor cell differentiationGO:004653020.023
regulation of response to external stimulusGO:00321012220.023
Human
cellular response to dna damage stimulusGO:00069743790.023
signal transduction by phosphorylationGO:00230142970.023
regulation of locomotionGO:00400123290.023
Human
tripartite regional subdivisionGO:000735120.023
cell part morphogenesisGO:00329901370.022
intracellular protein transportGO:00068862700.022
gtp metabolic processGO:00460392390.022
mapk cascadeGO:00001652880.022
negative regulation of cell proliferationGO:00082852280.022
peripheral nervous system developmentGO:000742220.022
regulation of mitotic cell cycleGO:00073461890.022
oocyte developmentGO:004859910.022
proteolysis involved in cellular protein catabolic processGO:00516032440.022
positive regulation of nucleotide metabolic processGO:00459812300.022
positive regulation of purine nucleotide catabolic processGO:00331231850.021
central nervous system developmentGO:00074171230.021
protein localization to organelleGO:00333652800.021
regulation of anatomical structure morphogenesisGO:00226032860.021
response to nitrogen compoundGO:19016981840.021
regulation of membrane potentialGO:0042391950.021
regulation of kinase activityGO:00435493140.021
cation homeostasisGO:00550801890.021
embryonic epithelial tube formationGO:000183840.021
regulation of neuronal synaptic plasticityGO:004816810.021
muscle contractionGO:0006936730.021
dephosphorylationGO:00163112090.021
neuron fate commitmentGO:004866320.021
negative regulation of multicellular organismal processGO:00512413170.021
cellular chemical homeostasisGO:00550821800.021
anterior posterior axis specification embryoGO:000859520.021
cellular homeostasisGO:00197251960.021
multicellular organismal response to stressGO:003355510.021
cranial nerve developmentGO:002154540.021
regulation of protein transportGO:00512232130.020
regulation of homeostatic processGO:00328441210.020
positive regulation of transferase activityGO:00513472270.020
translationGO:00064121320.020
cerebellum developmentGO:002154920.020
peptidyl tyrosine phosphorylationGO:00181081700.020
positive regulation of nucleoside metabolic processGO:00459791860.020
regulation of cellular response to stressGO:00801352440.020
oocyte differentiationGO:000999420.020
regulation of system processGO:00440571010.020
positive regulation of neural precursor cell proliferationGO:200017920.020
regulation of mapk cascadeGO:00434082620.020
negative regulation of protein modification processGO:00314002000.020
neural crest cell developmentGO:001403230.019
endomembrane system organizationGO:00102561960.019
regulation of cellular component biogenesisGO:00440872810.019
brain developmentGO:0007420970.019
regulation of purine nucleotide catabolic processGO:00331212050.019
positive regulation of gtpase activityGO:00435471660.019
cardiovascular system developmentGO:00723582620.019
enzyme linked receptor protein signaling pathwayGO:00071673030.019
regulation of vesicle mediated transportGO:00606271300.019
modification dependent macromolecule catabolic processGO:00436322120.019
metal ion homeostasisGO:00550651690.019
immune responseGO:00069553070.019
positive regulation of locomotionGO:00400171860.019
Human
positive regulation of nucleotide catabolic processGO:00308131850.019
regulation of nucleotide catabolic processGO:00308112050.019
regulation of cell developmentGO:00602841610.019
regulation of gtpase activityGO:00430871800.019
anion transportGO:00068201610.019
regulation of cell cycle processGO:00105642660.019
modification dependent protein catabolic processGO:00199412090.019
regulation of protein catabolic processGO:00421761550.019
positive regulation of cell deathGO:00109422630.019
Human
negative regulation of hydrolase activityGO:00513461820.018
regulation of cell morphogenesisGO:00226041530.018
regulation of transferase activityGO:00513383550.018
rhythmic behaviorGO:000762220.018
cellular protein complex assemblyGO:00436231880.018
rho protein signal transductionGO:0007266260.018
protein autophosphorylationGO:00467771230.018
chemotaxisGO:00069351570.018
Human
regulation of gtp catabolic processGO:00331241800.018
defense responseGO:00069523150.018
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathwayGO:000719640.018
regulation of intracellular transportGO:00323861950.018
monovalent inorganic cation transportGO:00156721280.018
organophosphate biosynthetic processGO:00904071630.018
inner ear morphogenesisGO:004247240.018
protein processingGO:00164852260.018
cerebral cortex cell migrationGO:002179530.018
multi organism cellular processGO:00447641560.018
cell morphogenesis involved in differentiationGO:00009041440.018
matingGO:000761810.018
protein targetingGO:00066051870.018
organ formationGO:004864530.018
negative regulation of cellular amino acid metabolic processGO:004576320.017
cellular ion homeostasisGO:00068731680.017
cell projection assemblyGO:00300311260.017
positive regulation of cell cycleGO:00457871400.017
peptidyl tyrosine modificationGO:00182121700.017
regulation of neurotransmitter secretionGO:004692830.017
protein maturationGO:00516042330.017
microtubule based processGO:00070172100.017
regulation of cell migrationGO:00303342890.017
Human
circadian behaviorGO:004851220.017
negative regulation of cellular amine metabolic processGO:003323930.017
spermatid differentiationGO:004851540.017
cellular response to nitrogen compoundGO:19016991440.017
detection of stimulusGO:0051606850.017
positive regulation of gtp catabolic processGO:00331261660.017
positive regulation of protein kinase activityGO:00458601900.017
behaviorGO:00076101120.017
Human
mitotic cell cycle processGO:19030472860.017
regulation of cell motilityGO:20001452990.017
Human
compound eye developmentGO:004874910.017
nucleoside phosphate biosynthetic processGO:19012931090.017
response to lipidGO:00339932060.017
exocytosisGO:0006887710.017
response to organonitrogen compoundGO:00102431560.017
head developmentGO:00603221080.016
spinal cord developmentGO:002151040.016
cellular cation homeostasisGO:00300031630.016
retinal ganglion cell axon guidanceGO:003129020.016
negative regulation of developmental processGO:00510932470.016
protein localization to membraneGO:00726571600.016
ubiquitin dependent protein catabolic processGO:00065112060.016
positive regulation of meiotic cell cycleGO:005144620.016
regulation of metal ion transportGO:00109591200.016
cellular response to organonitrogen compoundGO:00714171240.016
negative regulation of gliogenesisGO:001401430.016
muscle system processGO:0003012810.016
regulation of anatomical structure sizeGO:00900661010.016
positive regulation of kinase activityGO:00336742040.016
positive regulation of cell motilityGO:20001471770.016
Human
neuron projection regenerationGO:003110210.016
g protein coupled receptor signaling pathwayGO:00071862070.016
positive regulation of immune system processGO:00026842830.016
spermatid developmentGO:000728640.016
peptidyl serine phosphorylationGO:00181051010.016
Human
regulation of excitatory postsynaptic membrane potentialGO:006007910.016
forebrain neuron differentiationGO:002187930.016
long term memoryGO:000761620.016
sensory perception of smellGO:000760820.016
microtubule cytoskeleton organizationGO:00002261760.016
nucleotide biosynthetic processGO:00091651090.016
tissue regenerationGO:004224630.015
taxisGO:00423301570.015
Human
response to radiationGO:00093141510.015
posttranscriptional regulation of gene expressionGO:00106082130.015
wnt signaling pathwayGO:00160551560.015
embryonic camera type eye developmentGO:003107620.015
apoptotic signaling pathwayGO:00971902680.015
Human
divalent inorganic cation homeostasisGO:00725071360.015
negative regulation of synaptic transmissionGO:005080520.015
reactive oxygen species biosynthetic processGO:190340940.015
response to axon injuryGO:004867810.015
regulation of cytoskeleton organizationGO:00514931770.015
regulation of sequence specific dna binding transcription factor activityGO:00510902110.015
proteasomal protein catabolic processGO:00104981760.015
pituitary gland developmentGO:002198320.015
rna processingGO:00063962550.015
calcium ion transportGO:00068161470.015
positive regulation of programmed cell deathGO:00430682490.015
Human
positive regulation of cell migrationGO:00303351720.015
Human
regulation of neuroblast proliferationGO:190269230.015
actin mediated cell contractionGO:0070252120.015
regulation of apoptotic signaling pathwayGO:20012331750.015
organelle assemblyGO:00709251760.015
stem cell divisionGO:001714520.015
purine nucleotide biosynthetic processGO:0006164840.015
regulation of multi organism processGO:00439001570.015
cytokine productionGO:00018162470.015
regulation of cell projection organizationGO:00313441070.015
cellular carbohydrate metabolic processGO:0044262840.015
cellular potassium ion transportGO:0071804600.015
blood circulationGO:00080151130.014
small molecule biosynthetic processGO:00442831570.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
positive regulation of cellular component biogenesisGO:00440891580.014
synaptic transmissionGO:0007268610.014
positive regulation of cellular component movementGO:00512721810.014
Human
cellular metal ion homeostasisGO:00068751460.014
positive regulation of apoptotic processGO:00430652460.014
Human
somatic stem cell divisionGO:004810310.014
regulation of cytokine productionGO:00018172320.014
reactive nitrogen species metabolic processGO:200105730.014
neural tube formationGO:000184130.014
regulation of axon guidanceGO:190266730.014
somitogenesisGO:000175620.014
actin cytoskeleton organizationGO:00300362070.014
regulation of ras protein signal transductionGO:00465781550.014
positive regulation of ras gtpase activityGO:00323201170.014
response to light stimulusGO:0009416870.014
innate immune responseGO:00450871780.014
positive regulation of mapk cascadeGO:00434101900.014
cyclic nucleotide metabolic processGO:0009187820.014
glycoprotein metabolic processGO:00091001100.014
regulation of protein maturationGO:19033171500.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
membrane hyperpolarizationGO:006008110.014
energy homeostasisGO:009700930.014
synaptic vesicle exocytosisGO:001607930.014
positive regulation of response to external stimulusGO:0032103880.014
Human
postsynaptic membrane organizationGO:000194120.014
regulation of cytoplasmic transportGO:19036491490.014
release of cytoplasmic sequestered nf kappabGO:000858840.014
somatic stem cell maintenanceGO:003501940.014
morphogenesis of a polarized epitheliumGO:000173830.014
synaptic vesicle endocytosisGO:004848820.014
regulation of protein serine threonine kinase activityGO:00719001790.014
regulation of nervous system developmentGO:0051960880.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
immune system developmentGO:00025201950.014
male genitalia developmentGO:003053910.014
cellular calcium ion homeostasisGO:00068741170.014
sensory perceptionGO:00076001030.013
purine containing compound biosynthetic processGO:0072522880.013
cell divisionGO:00513011680.013
axon regenerationGO:003110310.013
sex determinationGO:000753030.013
establishment of protein localization to membraneGO:00901501210.013
dna repairGO:00062811980.013
astrocyte differentiationGO:004870840.013
circulatory system developmentGO:00723592620.013
potassium ion transmembrane transportGO:0071805600.013
syncytium formation by plasma membrane fusionGO:000076820.013
establishment of nucleus localizationGO:004002310.013
cell cycle phase transitionGO:00447701730.013
primary neural tube formationGO:001402030.013
i kappab kinase nf kappab signalingGO:00072491660.013
peptide transportGO:0015833740.013
response to fungusGO:000962040.013
divalent inorganic cation transportGO:00725111580.013
regulation of atrial cardiac muscle cell membrane repolarizationGO:006037240.013
regulation of ion transportGO:00432691890.013
negative regulation of cell sizeGO:004579230.013
monosaccharide metabolic processGO:0005996740.013
regulation of exocytosisGO:0017157460.013
signal releaseGO:0023061700.013
regulation of small gtpase mediated signal transductionGO:00510561560.013
response to hormoneGO:00097251750.013
positive regulation of protein transportGO:00512221350.013
nuclear transportGO:00511691790.013
cardiac cell fate determinationGO:006091330.013
negative regulation of neurological system processGO:003164520.013
cellular response to ammonium ionGO:007124240.013
regulation of ras gtpase activityGO:00323181280.013
carboxylic acid biosynthetic processGO:0046394970.013
axon cargo transportGO:000808820.013
regulation of cellular component sizeGO:0032535820.013
regulation of protein processingGO:00706131500.013
neuron projection morphogenesisGO:0048812500.013
visual behaviorGO:000763220.013
organic hydroxy compound metabolic processGO:19016151470.013
lipid localizationGO:00108761060.013
nucleus localizationGO:005164710.013
reactive oxygen species metabolic processGO:0072593750.013
cellular response to cytokine stimulusGO:00713451810.013
regulation of axon extension involved in axon guidanceGO:004884120.013
ribonucleotide biosynthetic processGO:0009260810.013
organic acid biosynthetic processGO:0016053970.013
cyclic nucleotide biosynthetic processGO:0009190610.013
negative regulation of protein maturationGO:19033181420.013
positive regulation of organelle organizationGO:00106381950.013
negative regulation of proteolysisGO:00458611320.012
purine ribonucleotide biosynthetic processGO:0009152790.012
tube closureGO:006060630.012
asymmetric stem cell divisionGO:009872210.012
negative regulation of organelle organizationGO:00106391260.012
regulation of wnt signaling pathwayGO:00301111230.012
nucleocytoplasmic transportGO:00069131760.012
establishment of protein localization to organelleGO:00725941720.012
anion transmembrane transportGO:0098656760.012
negative regulation of transportGO:00510511760.012
negative regulation of protein processingGO:00109551420.012
specification of organ identityGO:001009230.012
response to woundingGO:00096111680.012
ribose phosphate biosynthetic processGO:0046390820.012
epithelium developmentGO:00604292270.012
single organism cell adhesionGO:00986021790.012
eye photoreceptor cell differentiationGO:000175420.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
atp metabolic processGO:00460341760.012
cellular response to external stimulusGO:00714961110.012
positive regulation of proteolysisGO:00458621420.012
Human
negative regulation of phosphorylationGO:00423261740.012
positive regulation of axon extensionGO:004577340.012
reproductive processGO:00224141060.012
sequestering of calcium ionGO:0051208170.012
regulation of dephosphorylationGO:0035303960.012
endocytosisGO:00068971590.012
cellular response to organic cyclic compoundGO:00714071270.012
regulation of synaptic vesicle transportGO:190280330.012
interspecies interaction between organismsGO:00444191560.012
regulation of endopeptidase activityGO:00525481700.012
Human
plasma membrane organizationGO:00070091150.012
autophagyGO:0006914880.012
negative regulation of mitotic cell cycleGO:00459301020.012
rna interferenceGO:001624640.012
camp metabolic processGO:0046058610.012
cellular response to glucocorticoid stimulusGO:007138540.012
actin filament based movementGO:0030048170.012

PPM1E disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.026
central nervous system diseaseDOID:3311860.026
sensory system diseaseDOID:00501552030.026
disease of metabolismDOID:00146672950.025
eye and adnexa diseaseDOID:14921500.020
disease of cellular proliferationDOID:145661740.018
cancerDOID:1621670.018
organ system cancerDOID:00506861640.018
inherited metabolic disorderDOID:6552420.018
eye diseaseDOID:56141490.018
disease of mental healthDOID:150700.017
musculoskeletal system diseaseDOID:172230.017
retinal diseaseDOID:56791180.016
brain diseaseDOID:936730.014
neurodegenerative diseaseDOID:12891020.013
connective tissue diseaseDOID:651090.013
immune system diseaseDOID:29141550.012