Homo sapiens

147 known processes

PPM1B

protein phosphatase, Mg2+/Mn2+ dependent, 1B

(Aliases: PP2C-beta-X,PP2CB,MGC21657,PPC2BETAX,PP2CBETA)

PPM1B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
purine ribonucleoside metabolic processGO:00461284370.373
purine ribonucleoside triphosphate metabolic processGO:00092054110.329
organophosphate catabolic processGO:00464344300.313
nucleoside triphosphate metabolic processGO:00091414220.293
ras protein signal transductionGO:0007265730.293
Fly
small gtpase mediated signal transductionGO:0007264780.263
Fly
purine nucleotide catabolic processGO:00061954050.249
positive regulation of cellular component organizationGO:00511303760.219
nucleoside phosphate catabolic processGO:19012924120.217
purine nucleoside triphosphate catabolic processGO:00091463920.213
ribonucleoside triphosphate metabolic processGO:00091994120.210
ribonucleoside catabolic processGO:00424544060.203
nucleoside catabolic processGO:00091644080.198
synaptic transmissionGO:0007268610.187
purine ribonucleotide catabolic processGO:00091544040.181
lipid metabolic processGO:00066293810.163
purine nucleoside catabolic processGO:00061523980.163
purine nucleoside triphosphate metabolic processGO:00091444120.157
nucleotide catabolic processGO:00091664080.149
ribonucleotide catabolic processGO:00092614050.144
cell projection morphogenesisGO:00488581290.142
cellular macromolecule catabolic processGO:00442653800.136
cell morphogenesisGO:00009022960.135
purine ribonucleoside triphosphate catabolic processGO:00092073910.133
mitotic cell cycleGO:00002783260.127
Fly
purine ribonucleoside catabolic processGO:00461303980.123
purine containing compound catabolic processGO:00725234110.118
regulation of small gtpase mediated signal transductionGO:00510561560.118
Fly
response to hormoneGO:00097251750.114
system processGO:00030083490.113
cellular protein catabolic processGO:00442572610.111
response to uvGO:0009411730.109
Fly
cytoplasmic transportGO:00164823790.107
negative regulation of protein metabolic processGO:00512483910.103
Fly
microtubule based processGO:00070172100.102
negative regulation of cellular component organizationGO:00511292350.100
Human
neuromuscular junction developmentGO:000752830.098
response to abiotic stimulusGO:00096283360.096
Fly
regulation of ras protein signal transductionGO:00465781550.094
Fly
establishment or maintenance of apical basal cell polarityGO:003508820.093
oocyte developmentGO:004859910.092
ribonucleoside triphosphate catabolic processGO:00092033910.090
cell projection organizationGO:00300302520.089
peptidyl serine phosphorylationGO:00181051010.088
proteolysis involved in cellular protein catabolic processGO:00516032440.088
multicellular organismal agingGO:001025930.087
Fly
neuroblast proliferationGO:000740540.085
single organism cellular localizationGO:19025803320.084
determination of adult lifespanGO:000834020.083
Fly
somitogenesisGO:000175620.083
purine nucleoside monophosphate catabolic processGO:00091281580.081
protein catabolic processGO:00301633250.077
regulation of mapk cascadeGO:00434082620.076
Fly
neurological system processGO:00508771630.076
response to cytokineGO:00340972320.072
negative regulation of cellular protein metabolic processGO:00322693530.071
Fly
regulation of cell cycleGO:00517263930.070
peptidyl serine modificationGO:00182091060.068
cellular response to hormone stimulusGO:00328701250.067
dephosphorylationGO:00163112090.067
locomotory behaviorGO:000762610.066
mapk cascadeGO:00001652880.066
Fly
cellular response to dna damage stimulusGO:00069743790.065
cellular amino acid metabolic processGO:00065201160.065
cell part morphogenesisGO:00329901370.064
nucleoside triphosphate catabolic processGO:00091433940.064
glycosyl compound catabolic processGO:19016584130.064
cell morphogenesis involved in differentiationGO:00009041440.064
cellular lipid metabolic processGO:00442553030.063
cell developmentGO:00484683280.062
Fly
oogenesisGO:004847720.062
behavioral response to ethanolGO:004814920.058
nucleoside monophosphate metabolic processGO:00091231910.057
signal transduction by phosphorylationGO:00230142970.057
Fly
response to oxygen containing compoundGO:19017003690.056
secretionGO:00469032540.056
regulation of growthGO:00400081650.053
positive regulation of hydrolase activityGO:00513453310.053
oocyte differentiationGO:000999420.053
cellular component morphogenesisGO:00329893140.053
female gamete generationGO:000729220.052
regulation of body fluid levelsGO:0050878990.051
single organism membrane organizationGO:00448022680.051
gtp catabolic processGO:00061842370.051
intracellular protein transportGO:00068862700.049
post embryonic developmentGO:000979120.048
Fly
actin filament based movementGO:0030048170.047
generation of neuronsGO:00486991520.047
Fly
cellular response to endogenous stimulusGO:00714953360.047
Human Zebrafish
negative regulation of protein modification processGO:00314002000.047
Fly
purine ribonucleoside monophosphate catabolic processGO:00091691580.045
cellular response to oxygen containing compoundGO:19017012760.045
microtubule bundle formationGO:0001578150.045
cell divisionGO:00513011680.045
positive regulation of programmed cell deathGO:00430682490.045
regulation of protein modification by small protein conjugation or removalGO:19033201070.044
positive regulation of cellular amine metabolic processGO:003324070.044
regulation of anatomical structure morphogenesisGO:00226032860.044
Fly
organelle assemblyGO:00709251760.043
proteasomal protein catabolic processGO:00104981760.043
enzyme linked receptor protein signaling pathwayGO:00071673030.042
Human Zebrafish
positive regulation of catabolic processGO:00098963100.041
positive regulation of cell proliferationGO:00082843010.041
apoptotic signaling pathwayGO:00971902680.041
response to light stimulusGO:0009416870.040
Fly
spermatid differentiationGO:004851540.040
positive regulation of cell deathGO:00109422630.040
metal ion transportGO:00300012720.040
regulation of cellular amino acid metabolic processGO:000652160.040
regulation of kinase activityGO:00435493140.039
Fly
mitotic cell cycle processGO:19030472860.039
endomembrane system organizationGO:00102561960.039
regulation of cell projection organizationGO:00313441070.038
neuron differentiationGO:00301821380.038
Fly
regulation of vesicle mediated transportGO:00606271300.038
nervous system developmentGO:00073992930.038
Fly
organic hydroxy compound metabolic processGO:19016151470.037
behaviorGO:00076101120.037
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.037
ribonucleoside monophosphate catabolic processGO:00091581580.036
atp catabolic processGO:00062001570.036
nuclear divisionGO:00002801280.036
lipid transportGO:0006869900.036
cellular response to cytokine stimulusGO:00713451810.036
regulation of cellular ketone metabolic processGO:0010565500.036
carbohydrate metabolic processGO:00059752070.035
regulation of cell morphogenesis involved in differentiationGO:0010769830.035
positive regulation of phosphorylationGO:00423273940.035
regulation of multi organism processGO:00439001570.035
negative regulation of multicellular organismal processGO:00512413170.035
ribonucleoside monophosphate metabolic processGO:00091611870.035
positive regulation of cellular catabolic processGO:00313312840.035
neurotransmitter secretionGO:000726940.035
organonitrogen compound biosynthetic processGO:19015662000.035
secretion by cellGO:00329402260.035
negative regulation of growthGO:0045926970.035
positive regulation of transportGO:00510503360.035
positive regulation of mapk cascadeGO:00434101900.034
protein autophosphorylationGO:00467771230.034
microtubule cytoskeleton organizationGO:00002261760.034
amine metabolic processGO:0009308440.034
cellular amine metabolic processGO:0044106410.033
organelle fissionGO:00482851490.032
vesicle mediated transportGO:00161923710.032
organic hydroxy compound transportGO:0015850630.032
response to other organismGO:00517072610.032
mitochondrion organizationGO:00070051560.032
regulation of cell morphogenesisGO:00226041530.032
negative regulation of programmed cell deathGO:00430693210.032
glycerophospholipid metabolic processGO:0006650840.031
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.031
protein localization to organelleGO:00333652800.031
negative regulation of catalytic activityGO:00430863350.031
Fly
positive regulation of peptidase activityGO:0010952880.031
regulation of cell cycle processGO:00105642660.031
establishment or maintenance of bipolar cell polarityGO:006124520.031
regulation of cellular component biogenesisGO:00440872810.031
Human
negative regulation of cell deathGO:00605483450.031
reproductive processGO:00224141060.030
epithelium developmentGO:00604292270.030
Fly
cellular ketone metabolic processGO:0042180800.030
embryo developmentGO:00097901230.030
Fly
defense responseGO:00069523150.030
negative regulation of phosphorus metabolic processGO:00105632670.030
Fly
regulation of exocytosisGO:0017157460.029
dna repairGO:00062811980.029
endosomal transportGO:00161971290.029
regulation of cellular component sizeGO:0032535820.029
protein localization to plasma membraneGO:0072659930.029
regulation of protein serine threonine kinase activityGO:00719001790.029
Fly
response to growth factorGO:00708482050.028
Human Zebrafish
protein maturationGO:00516042330.028
plasma membrane organizationGO:00070091150.028
response to biotic stimulusGO:00096072760.028
response to insulinGO:0032868450.028
purine ribonucleoside monophosphate metabolic processGO:00091671860.028
segmentationGO:003528240.028
cellular response to nitrogen compoundGO:19016991440.027
growthGO:00400072020.027
gtp metabolic processGO:00460392390.027
glycerolipid metabolic processGO:00464861070.027
response to lipidGO:00339932060.027
fatty acid metabolic processGO:00066311150.027
agingGO:0007568660.027
Fly
regulation of protein localizationGO:00328802960.027
nucleoside monophosphate catabolic processGO:00091251590.026
embryonic morphogenesisGO:0048598850.026
Fly
modification dependent macromolecule catabolic processGO:00436322120.026
sensory perceptionGO:00076001030.026
mitotic cell cycle phase transitionGO:00447721620.026
chromosome segregationGO:00070591140.026
response to virusGO:00096151260.026
regulation of secretionGO:00510461940.026
regulation of cell differentiationGO:00455953930.025
Fly
positive regulation of purine nucleotide metabolic processGO:19005442270.025
regulation of proteolysisGO:00301622930.025
positive regulation of proteolysisGO:00458621420.025
chromatin modificationGO:00165682980.025
spermatid developmentGO:000728640.025
regulation of ion transportGO:00432691890.025
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.025
transmembrane transportGO:00550853990.024
monocarboxylic acid metabolic processGO:00327871850.024
purine nucleoside monophosphate metabolic processGO:00091261860.023
positive regulation of nucleotide metabolic processGO:00459812300.023
hindbrain developmentGO:003090230.023
regulation of cytoskeleton organizationGO:00514931770.023
positive regulation of protein phosphorylationGO:00019343130.023
phospholipid metabolic processGO:0006644990.023
positive regulation of ras gtpase activityGO:00323201170.023
chemical homeostasisGO:00488783060.023
regulation of i kappab kinase nf kappab signalingGO:00431221620.022
anatomical structure formation involved in morphogenesisGO:00486462840.022
defense response to other organismGO:00985421290.022
regulation of peptidase activityGO:00525471800.022
neuron developmentGO:00486661130.022
actin filament based processGO:00300292240.022
signal releaseGO:0023061700.021
monovalent inorganic cation transportGO:00156721280.021
modification dependent protein catabolic processGO:00199412090.021
negative regulation of transferase activityGO:00513481240.021
Fly
exocytosisGO:0006887710.021
negative regulation of transportGO:00510511760.021
maintenance of cell polarityGO:003001120.021
macromolecule methylationGO:0043414970.021
cellular protein complex assemblyGO:00436231880.020
Human
response to peptideGO:1901652650.020
serine phosphorylation of stat proteinGO:004250140.020
regulation of erk1 and erk2 cascadeGO:0070372990.020
Fly
regulation of stress activated mapk cascadeGO:0032872840.020
Fly
negative regulation of intracellular signal transductionGO:19025321830.020
protein complex disassemblyGO:0043241520.020
negative regulation of protein phosphorylationGO:00019331400.019
Fly
single organism carbohydrate metabolic processGO:00447231930.019
atp metabolic processGO:00460341760.019
negative regulation of apoptotic processGO:00430663160.019
protein ubiquitinationGO:00165673140.019
cation transmembrane transportGO:00986552380.019
regulation of apoptotic signaling pathwayGO:20012331750.019
regulation of nucleocytoplasmic transportGO:0046822980.019
positive regulation of kinase activityGO:00336742040.019
cell cell signalingGO:00072671550.019
regulation of viral processGO:00507921030.018
regulation of neuron projection developmentGO:0010975570.018
protein targetingGO:00066051870.018
maintenance of locationGO:00512351120.018
regulation of protein ubiquitinationGO:0031396950.018
positive regulation of apoptotic processGO:00430652460.018
associative learningGO:000830610.018
primary neural tube formationGO:001402030.018
regulation of cell divisionGO:00513021160.018
jnk cascadeGO:0007254800.018
Fly
response to radiationGO:00093141510.018
Fly
protein alkylationGO:0008213740.018
positive regulation of protein kinase activityGO:00458601900.018
negative regulation of protein serine threonine kinase activityGO:0071901570.017
Fly
regulation of protein complex assemblyGO:00432541470.017
Human
protein methylationGO:0006479740.017
memoryGO:000761330.017
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.017
cation transportGO:00068123310.017
regulation of ras gtpase activityGO:00323181280.017
golgi vesicle transportGO:0048193800.017
membrane organizationGO:00610242920.017
regulation of intracellular transportGO:00323861950.017
regulation of meiosisGO:004002030.017
biological adhesionGO:00226103310.017
organelle localizationGO:0051640840.016
guanosine containing compound metabolic processGO:19010682440.016
sleepGO:003043120.016
cellular response to insulin stimulusGO:0032869410.016
regulation of cell growthGO:00015581350.016
regulation of response to external stimulusGO:00321012220.016
morphogenesis of embryonic epitheliumGO:001633140.016
Fly
positive regulation of transferase activityGO:00513472270.016
response to external biotic stimulusGO:00432072610.016
intrinsic apoptotic signaling pathwayGO:00971931270.015
protein oligomerizationGO:00512591730.015
regulation of mitotic cell cycleGO:00073461890.015
regulation of immune effector processGO:0002697910.015
regulation of cell developmentGO:00602841610.015
Fly
response to bacteriumGO:00096171440.015
cell fate determinationGO:000170930.015
central nervous system developmentGO:00074171230.015
reproductionGO:0000003630.015
actin cytoskeleton organizationGO:00300362070.015
cilium morphogenesisGO:0060271750.015
rho protein signal transductionGO:0007266260.015
regulation of cellular amine metabolic processGO:0033238110.015
inorganic cation transmembrane transportGO:00986621940.015
regulation of cellular carbohydrate metabolic processGO:0010675470.015
ameboidal type cell migrationGO:00016671350.014
ribonucleoprotein complex biogenesisGO:00226131160.014
regulation of protein kinase activityGO:00458592890.014
Fly
g protein coupled receptor signaling pathwayGO:00071862070.014
regulation of purine nucleotide metabolic processGO:19005422640.014
cellular response to growth factor stimulusGO:00713631970.014
Human Zebrafish
negative regulation of protein kinase activityGO:0006469980.014
Fly
detection of abiotic stimulusGO:0009582150.014
stem cell divisionGO:001714520.014
cell morphogenesis involved in neuron differentiationGO:0048667440.014
lipid modificationGO:0030258840.014
regulation of neural precursor cell proliferationGO:200017740.014
circulatory system developmentGO:00723592620.014
regulation of cell motilityGO:20001452990.014
response to organic cyclic compoundGO:00140702040.014
neural tube formationGO:000184130.014
response to tumor necrosis factorGO:0034612760.014
erk1 and erk2 cascadeGO:00703711040.014
Fly
lipid homeostasisGO:0055088390.014
taxisGO:00423301570.014
regulation of homeostatic processGO:00328441210.014
negative regulation of organelle organizationGO:00106391260.014
single organismal cell cell adhesionGO:00163371480.014
autophagyGO:0006914880.013
nucleoside phosphate biosynthetic processGO:19012931090.013
regulation of cellular response to stressGO:00801352440.013
Fly
cellular component disassemblyGO:0022411920.013
positive regulation of gtpase activityGO:00435471660.013
response to nitrogen compoundGO:19016981840.013
response to organonitrogen compoundGO:00102431560.013
negative regulation of apoptotic signaling pathwayGO:2001234970.013
somatic stem cell divisionGO:004810310.013
metencephalon developmentGO:002203720.013
regulation of growth rateGO:004000910.013
receptor metabolic processGO:0043112810.013
posttranscriptional regulation of gene expressionGO:00106082130.013
methylationGO:00322591060.013
positive regulation of cell projection organizationGO:0031346640.013
positive regulation of cell developmentGO:0010720920.013
Fly
guanosine containing compound catabolic processGO:19010692390.013
establishment of organelle localizationGO:0051656590.013
negative regulation of secretionGO:0051048580.013
cell growthGO:00160491600.013
histone modificationGO:00165702510.013
regulation of protein catabolic processGO:00421761550.013
phosphatidylinositol metabolic processGO:0046488530.013
intracellular receptor signaling pathwayGO:00305221040.013
negative regulation of phosphate metabolic processGO:00459362670.013
Fly
response to peptide hormoneGO:0043434610.013
negative regulation of protein processingGO:00109551420.013
regulation of dna metabolic processGO:00510521530.013
cilium assemblyGO:0042384630.013
translationGO:00064121320.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.013
Human Zebrafish
monosaccharide metabolic processGO:0005996740.013
i kappab kinase nf kappab signalingGO:00072491660.012
negative regulation of mapk cascadeGO:0043409560.012
Fly
stress activated mapk cascadeGO:0051403930.012
Fly
protein homooligomerizationGO:00512601000.012
regulation of map kinase activityGO:00434051080.012
Fly
regulation of anatomical structure sizeGO:00900661010.012
positive regulation of protein serine threonine kinase activityGO:00719021190.012
carbohydrate derivative biosynthetic processGO:19011372070.012
wnt signaling pathwayGO:00160551560.012
Human
axon developmentGO:0061564340.012
detection of mechanical stimulusGO:005098240.012
protein localization to membraneGO:00726571600.012
regulation of nuclear divisionGO:0051783650.012
negative regulation of cell proliferationGO:00082852280.012
cellular response to organonitrogen compoundGO:00714171240.012
regulation of cellular component movementGO:00512703340.012
regulation of neurogenesisGO:0050767820.012
Fly
negative regulation of cell growthGO:0030308830.012
negative regulation of cell differentiationGO:00455961710.012
meiosis iGO:000712740.012
peptide transportGO:0015833740.012
positive regulation of purine nucleotide catabolic processGO:00331231850.011
organ morphogenesisGO:00098871470.011
Fly
positive regulation of cytoskeleton organizationGO:0051495830.011
innate immune responseGO:00450871780.011
neural tube closureGO:000184330.011
central nervous system neuron axonogenesisGO:002195530.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
regulation of endopeptidase activityGO:00525481700.011
embryonic epithelial tube formationGO:000183840.011
protein processingGO:00164852260.011
negative regulation of kinase activityGO:00336731060.011
Fly
response to alcoholGO:0097305640.011
positive regulation of immune system processGO:00026842830.011
cilium organizationGO:0044782680.011
regulation of chromosome organizationGO:00330441030.011
neuron projection morphogenesisGO:0048812500.011
cardiovascular system developmentGO:00723582620.011
cell projection assemblyGO:00300311260.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.011
Human Zebrafish
tube morphogenesisGO:0035239950.011
regulation of nervous system developmentGO:0051960880.011
Fly
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.011
protein dephosphorylationGO:0006470810.011
defense response to virusGO:0051607710.011
negative regulation of phosphorylationGO:00423261740.011
Fly
transforming growth factor beta receptor signaling pathwayGO:0007179760.011
Human Zebrafish
embryo development ending in birth or egg hatchingGO:0009792340.011
Fly
alcohol metabolic processGO:00060661140.010
carbohydrate biosynthetic processGO:0016051420.010
detection of stimulus involved in sensory perceptionGO:0050906430.010
gland developmentGO:0048732480.010
protein modification by small protein conjugationGO:00324463420.010
rna processingGO:00063962550.010
regulation of jnk cascadeGO:0046328730.010
Fly
regulation of sequence specific dna binding transcription factor activityGO:00510902110.010
response to nutrient levelsGO:0031667810.010
compound eye developmentGO:004874910.010
Fly
circadian behaviorGO:004851220.010
detection of stimulusGO:0051606850.010
positive regulation of synaptic transmissionGO:005080640.010
muscle tissue developmentGO:0060537620.010
regulation of protein import into nucleusGO:0042306780.010
brain developmentGO:0007420970.010
neurogenesisGO:00220081690.010
Fly
regulation of dna repairGO:0006282470.010
regulation of cellular response to growth factor stimulusGO:0090287760.010
Human Zebrafish
positive regulation of jnk cascadeGO:0046330520.010
organic acid biosynthetic processGO:0016053970.010

PPM1B disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.021
disease of cellular proliferationDOID:145661740.019
nervous system diseaseDOID:8634310.018
central nervous system diseaseDOID:3311860.018
cancerDOID:1621670.014
musculoskeletal system diseaseDOID:172230.011
organ system cancerDOID:00506861640.011