Homo sapiens

7 known processes

PPM1H

protein phosphatase, Mg2+/Mn2+ dependent, 1H

(Aliases: ARHCL1,FLJ13253,KIAA1157,NERPP-2C,URCC2)

PPM1H biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.062
cellular amino acid metabolic processGO:00065201160.056
amine metabolic processGO:0009308440.048
cellular amine metabolic processGO:0044106410.044
regulation of cellular amine metabolic processGO:0033238110.041
cellular ketone metabolic processGO:0042180800.040
multicellular organismal agingGO:001025930.040
determination of adult lifespanGO:000834020.040
regulation of cellular amino acid metabolic processGO:000652160.039
locomotory behaviorGO:000762610.039
organophosphate catabolic processGO:00464344300.036
positive regulation of cellular amine metabolic processGO:003324070.036
nucleoside triphosphate metabolic processGO:00091414220.036
regulation of cellular ketone metabolic processGO:0010565500.035
purine ribonucleoside metabolic processGO:00461284370.035
ribonucleoside catabolic processGO:00424544060.034
female gamete generationGO:000729220.034
positive regulation of cellular amino acid metabolic processGO:004576430.034
purine containing compound catabolic processGO:00725234110.034
purine nucleotide catabolic processGO:00061954050.033
ras protein signal transductionGO:0007265730.033
oogenesisGO:004847720.033
ribonucleoside triphosphate metabolic processGO:00091994120.033
nucleoside phosphate catabolic processGO:19012924120.033
ribonucleoside triphosphate catabolic processGO:00092033910.032
purine ribonucleoside triphosphate metabolic processGO:00092054110.032
small gtpase mediated signal transductionGO:0007264780.032
purine nucleoside triphosphate metabolic processGO:00091444120.032
purine ribonucleotide catabolic processGO:00091544040.032
glycosyl compound catabolic processGO:19016584130.031
purine nucleoside catabolic processGO:00061523980.031
nucleoside catabolic processGO:00091644080.031
lipid metabolic processGO:00066293810.031
purine nucleoside triphosphate catabolic processGO:00091463920.031
nucleotide catabolic processGO:00091664080.030
system processGO:00030083490.030
ribonucleotide catabolic processGO:00092614050.030
cellular lipid metabolic processGO:00442553030.030
purine ribonucleoside catabolic processGO:00461303980.030
purine ribonucleoside triphosphate catabolic processGO:00092073910.030
nucleoside triphosphate catabolic processGO:00091433940.030
segmentationGO:003528240.029
vesicle mediated transportGO:00161923710.029
cytoplasmic transportGO:00164823790.028
positive regulation of catabolic processGO:00098963100.028
negative regulation of protein metabolic processGO:00512483910.028
negative regulation of catalytic activityGO:00430863350.028
positive regulation of transportGO:00510503360.028
membrane organizationGO:00610242920.027
negative regulation of cellular protein metabolic processGO:00322693530.027
positive regulation of hydrolase activityGO:00513453310.027
neuromuscular junction developmentGO:000752830.027
positive regulation of cellular component organizationGO:00511303760.026
single organism membrane organizationGO:00448022680.026
actin filament based processGO:00300292240.026
single organism cellular localizationGO:19025803320.025
chemical homeostasisGO:00488783060.025
immune responseGO:00069553070.025
cellular macromolecule catabolic processGO:00442653800.025
rho protein signal transductionGO:0007266260.025
negative regulation of phosphate metabolic processGO:00459362670.025
protein catabolic processGO:00301633250.024
cation transportGO:00068123310.024
transmembrane transportGO:00550853990.024
memoryGO:000761330.024
regulation of cell cycleGO:00517263930.024
cellular component morphogenesisGO:00329893140.024
dephosphorylationGO:00163112090.024
negative regulation of phosphorus metabolic processGO:00105632670.024
cell morphogenesisGO:00009022960.024
biological adhesionGO:00226103310.024
positive regulation of cellular catabolic processGO:00313312840.023
cell adhesionGO:00071553250.023
regulation of nucleotide metabolic processGO:00061402690.023
regulation of cell differentiationGO:00455953930.023
regenerationGO:003109940.023
nervous system developmentGO:00073992930.022
regulation of transferase activityGO:00513383550.022
regulation of purine nucleotide metabolic processGO:19005422640.022
regulation of protein localizationGO:00328802960.022
guanosine containing compound catabolic processGO:19010692390.022
ion homeostasisGO:00508012300.022
gtp catabolic processGO:00061842370.022
anterior posterior axis specificationGO:000994820.022
secretionGO:00469032540.022
positive regulation of phosphorylationGO:00423273940.022
regulation of cellular component movementGO:00512703340.022
cellular macromolecular complex assemblyGO:00346223240.021
defense responseGO:00069523150.021
protein localization to organelleGO:00333652800.021
cell projection organizationGO:00300302520.021
morphogenesis of embryonic epitheliumGO:001633140.021
response to oxygen containing compoundGO:19017003690.021
response to abiotic stimulusGO:00096283360.021
neurotransmitter secretionGO:000726940.021
blastoderm segmentationGO:000735020.021
regulation of proteolysisGO:00301622930.021
regulation of kinase activityGO:00435493140.021
ion transmembrane transportGO:00342203380.021
carbohydrate metabolic processGO:00059752070.021
intracellular protein transportGO:00068862700.021
regulation of nucleoside metabolic processGO:00091182090.021
adult locomotory behaviorGO:000834410.020
cellular response to dna damage stimulusGO:00069743790.020
mitotic cell cycleGO:00002783260.020
cell developmentGO:00484683280.020
secretion by cellGO:00329402260.020
cellular protein catabolic processGO:00442572610.020
regulation of anatomical structure morphogenesisGO:00226032860.020
gtp metabolic processGO:00460392390.020
negative regulation of cell deathGO:00605483450.020
guanosine containing compound metabolic processGO:19010682440.020
metal ion transportGO:00300012720.020
negative regulation of multicellular organismal processGO:00512413170.020
signal transduction by phosphorylationGO:00230142970.020
cardiac muscle cell contractionGO:008600340.020
regulation of protein kinase activityGO:00458592890.020
carbohydrate derivative biosynthetic processGO:19011372070.020
negative regulation of cellular component organizationGO:00511292350.020
positive regulation of purine nucleotide catabolic processGO:00331231850.020
negative regulation of cellular amino acid metabolic processGO:004576320.019
small molecule biosynthetic processGO:00442831570.019
protein maturationGO:00516042330.019
endomembrane system organizationGO:00102561960.019
positive regulation of nucleotide metabolic processGO:00459812300.019
organonitrogen compound biosynthetic processGO:19015662000.019
negative regulation of cellular amine metabolic processGO:003323930.019
protein modification by small protein conjugationGO:00324463420.019
oxidation reduction processGO:00551143960.019
hindbrain developmentGO:003090230.019
regulation of cellular component biogenesisGO:00440872810.019
rhythmic behaviorGO:000762220.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
regulation of cellular response to stressGO:00801352440.019
oocyte developmentGO:004859910.019
regulation of purine nucleotide catabolic processGO:00331212050.019
protein ubiquitinationGO:00165673140.019
oocyte differentiationGO:000999420.019
cellular response to oxygen containing compoundGO:19017012760.019
regulation of nucleotide catabolic processGO:00308112050.019
photoreceptor cell differentiationGO:004653020.019
proteolysis involved in cellular protein catabolic processGO:00516032440.019
spermatid differentiationGO:004851540.018
mitotic cell cycle processGO:19030472860.018
cell fate determinationGO:000170930.018
negative regulation of programmed cell deathGO:00430693210.018
maintenance of locationGO:00512351120.018
regulation of locomotionGO:00400123290.018
negative regulation of cell proliferationGO:00082852280.018
single organism carbohydrate metabolic processGO:00447231930.018
cellular response to endogenous stimulusGO:00714953360.018
mapk cascadeGO:00001652880.018
negative regulation of apoptotic processGO:00430663160.018
regulation of establishment of protein localizationGO:00702012420.018
regulation of cell cycle processGO:00105642660.018
regulation of synaptic plasticityGO:004816730.018
positive regulation of synaptic transmissionGO:005080640.018
lipid biosynthetic processGO:00086101770.018
peripheral nervous system developmentGO:000742220.018
embryonic epithelial tube formationGO:000183840.018
positive regulation of immune system processGO:00026842830.018
cation homeostasisGO:00550801890.018
positive regulation of nucleoside metabolic processGO:00459791860.018
innate immune responseGO:00450871780.018
negative regulation of hydrolase activityGO:00513461820.018
positive regulation of cell deathGO:00109422630.018
positive regulation of developmental processGO:00510943140.018
enzyme linked receptor protein signaling pathwayGO:00071673030.018
regulation of intracellular transportGO:00323861950.018
apoptotic signaling pathwayGO:00971902680.017
regulation of secretionGO:00510461940.017
positive regulation of nucleotide catabolic processGO:00308131850.017
response to external biotic stimulusGO:00432072610.017
cellular homeostasisGO:00197251960.017
spermatid developmentGO:000728640.017
matingGO:000761810.017
protein processingGO:00164852260.017
response to biotic stimulusGO:00096072760.017
negative regulation of protein modification processGO:00314002000.017
microtubule based processGO:00070172100.017
anterior posterior axis specification embryoGO:000859520.017
compound eye developmentGO:004874910.017
regulation of gtp catabolic processGO:00331241800.017
positive regulation of apoptotic processGO:00430652460.017
regulation of response to external stimulusGO:00321012220.017
neurological system processGO:00508771630.017
circadian behaviorGO:004851220.017
regulation of cell motilityGO:20001452990.017
regulation of protein transportGO:00512232130.017
inorganic ion transmembrane transportGO:00986602310.017
cation transmembrane transportGO:00986552380.017
tripartite regional subdivisionGO:000735120.017
response to other organismGO:00517072610.017
positive regulation of protein phosphorylationGO:00019343130.017
nerve developmentGO:002167540.017
associative learningGO:000830610.017
nitrogen compound transportGO:00717051910.016
actin filament based movementGO:0030048170.016
positive regulation of programmed cell deathGO:00430682490.016
regulation of gtpase activityGO:00430871800.016
inner ear morphogenesisGO:004247240.016
regulation of mapk cascadeGO:00434082620.016
regulation of cell migrationGO:00303342890.016
protein targetingGO:00066051870.016
chromatin organizationGO:00063253510.016
reactive oxygen species biosynthetic processGO:190340940.016
carboxylic acid biosynthetic processGO:0046394970.016
organic acid biosynthetic processGO:0016053970.016
metencephalon developmentGO:002203720.016
negative regulation of intracellular signal transductionGO:19025321830.016
motor neuron axon guidanceGO:000804520.016
monocarboxylic acid metabolic processGO:00327871850.016
positive regulation of cell proliferationGO:00082843010.016
cytokine productionGO:00018162470.016
protein localization to membraneGO:00726571600.016
cellular chemical homeostasisGO:00550821800.016
positive regulation of transferase activityGO:00513472270.016
actin mediated cell contractionGO:0070252120.016
inorganic cation transmembrane transportGO:00986621940.016
regulation of secretion by cellGO:19035301770.016
positive regulation of gtp catabolic processGO:00331261660.015
modification dependent macromolecule catabolic processGO:00436322120.015
regulation of cytokine productionGO:00018172320.015
release of cytoplasmic sequestered nf kappabGO:000858840.015
limbic system developmentGO:002176130.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
positive regulation of gtpase activityGO:00435471660.015
cellular protein complex assemblyGO:00436231880.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
histone modificationGO:00165702510.015
regulation of ras protein signal transductionGO:00465781550.015
organophosphate biosynthetic processGO:00904071630.015
regulation of cytoskeleton organizationGO:00514931770.015
proteasomal protein catabolic processGO:00104981760.015
nucleoside monophosphate metabolic processGO:00091231910.015
neuroblast proliferationGO:000740540.015
response to fungusGO:000962040.015
purine nucleoside monophosphate metabolic processGO:00091261860.015
negative regulation of phosphorylationGO:00423261740.015
anion transportGO:00068201610.015
reactive nitrogen species metabolic processGO:200105730.015
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.015
regulation of reactive oxygen species biosynthetic processGO:190342630.015
chromatin modificationGO:00165682980.015
regulation of small gtpase mediated signal transductionGO:00510561560.015
modification dependent protein catabolic processGO:00199412090.015
organelle assemblyGO:00709251760.015
actin cytoskeleton organizationGO:00300362070.015
cellular cation homeostasisGO:00300031630.015
glycoprotein metabolic processGO:00091001100.015
negative regulation of cell cycleGO:00457861930.014
morphogenesis of a polarized epitheliumGO:000173830.014
reactive oxygen species metabolic processGO:0072593750.014
cell growthGO:00160491600.014
metal ion homeostasisGO:00550651690.014
positive regulation of organelle organizationGO:00106381950.014
posttranscriptional regulation of gene expressionGO:00106082130.014
organ formationGO:004864530.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
forebrain generation of neuronsGO:002187230.014
covalent chromatin modificationGO:00165692540.014
regulation of protein catabolic processGO:00421761550.014
neural tube formationGO:000184130.014
ubiquitin dependent protein catabolic processGO:00065112060.014
response to cytokineGO:00340972320.014
atp metabolic processGO:00460341760.014
regulation of neural precursor cell proliferationGO:200017740.014
regulation of cell morphogenesisGO:00226041530.014
response to axon injuryGO:004867810.014
epithelium developmentGO:00604292270.014
establishment or maintenance of bipolar cell polarityGO:006124520.014
regulation of immune responseGO:00507762010.014
response to organic cyclic compoundGO:00140702040.014
positive regulation of protein kinase activityGO:00458601900.014
negative regulation of transportGO:00510511760.014
cellular ion homeostasisGO:00068731680.014
establishment of protein localization to organelleGO:00725941720.014
positive regulation of cell differentiationGO:00455972110.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
syncytium formation by plasma membrane fusionGO:000076820.014
regulation of vesicle mediated transportGO:00606271300.014
neurogenesisGO:00220081690.014
organic hydroxy compound metabolic processGO:19016151470.014
negative regulation of developmental processGO:00510932470.014
regulation of growthGO:00400081650.014
positive regulation of kinase activityGO:00336742040.013
sensory perception of smellGO:000760820.013
startle responseGO:000196430.013
cell divisionGO:00513011680.013
protein oligomerizationGO:00512591730.013
tissue regenerationGO:004224630.013
rna interferenceGO:001624640.013
sequestering of metal ionGO:0051238240.013
establishment of planar polarityGO:000173630.013
regulation of neurotransmitter secretionGO:004692830.013
cellular metal ion homeostasisGO:00068751460.013
regulation of apoptotic signaling pathwayGO:20012331750.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
positive regulation of secretionGO:00510471160.013
cell cycle phase transitionGO:00447701730.013
protein o linked glycosylation via threonineGO:001824340.013
sequestering of calcium ionGO:0051208170.013
rna processingGO:00063962550.013
cellular response to cytokine stimulusGO:00713451810.013
microtubule cytoskeleton organizationGO:00002261760.013
visual behaviorGO:000763220.013
sulfur compound metabolic processGO:00067901010.013
endosomal transportGO:00161971290.013
regulation of protein maturationGO:19033171500.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
interspecies interaction between organismsGO:00444191560.013
cell projection assemblyGO:00300311260.013
wnt signaling pathwayGO:00160551560.013
somitogenesisGO:000175620.013
sex determinationGO:000753030.013
growthGO:00400072020.013
symbiosis encompassing mutualism through parasitismGO:00444031560.013
regulation of endopeptidase activityGO:00525481700.013
regulation of protein processingGO:00706131500.013
cerebellum developmentGO:002154920.013
primary neural tube formationGO:001402030.013
mitochondrion organizationGO:00070051560.013
spinal cord developmentGO:002151040.013
tube closureGO:006060630.013
salivary gland morphogenesisGO:000743540.013
negative regulation of protein processingGO:00109551420.013
divalent metal ion transportGO:00708381520.013
divalent inorganic cation transportGO:00725111580.013
single organism cell adhesionGO:00986021790.013
stem cell divisionGO:001714520.013
cofactor metabolic processGO:0051186870.013
lung alveolus developmentGO:004828640.013
regulation of multi organism processGO:00439001570.013
thymus developmentGO:004853830.013
generation of neuronsGO:00486991520.013
multi organism cellular processGO:00447641560.013
regulation of peptidase activityGO:00525471800.012
long term memoryGO:000761620.012
cardiovascular system developmentGO:00723582620.012
positive regulation of secretion by cellGO:19035321080.012
regulation of cell growthGO:00015581350.012
regulation of meiotic cell cycleGO:005144540.012
regulation of ras gtpase activityGO:00323181280.012
cell activationGO:00017752130.012
regulation of cell developmentGO:00602841610.012
nucleoside monophosphate catabolic processGO:00091251590.012
nuclear transportGO:00511691790.012
cell part morphogenesisGO:00329901370.012
response to growth factorGO:00708482050.012
myoblast fusionGO:000752010.012
monovalent inorganic cation transportGO:00156721280.012
regulation of mitotic cell cycleGO:00073461890.012
phospholipid metabolic processGO:0006644990.012
positive regulation of cytokine productionGO:00018191670.012
negative regulation of protein phosphorylationGO:00019331400.012
divalent inorganic cation homeostasisGO:00725071360.012
negative regulation of organelle organizationGO:00106391260.012
regulation of ion transportGO:00432691890.012
organic anion transportGO:00157111030.012
dna repairGO:00062811980.012
regulation of protein serine threonine kinase activityGO:00719001790.012
response to lipidGO:00339932060.012
cell projection morphogenesisGO:00488581290.012
nucleocytoplasmic transportGO:00069131760.012
regulation of cytoplasmic transportGO:19036491490.012
positive regulation of cell migrationGO:00303351720.012
positive regulation of cellular component biogenesisGO:00440891580.012
endocytosisGO:00068971590.012
protein o linked glycosylation via serineGO:001824230.012
positive regulation of mapk cascadeGO:00434101900.012
neural tube closureGO:000184330.012
response to nitrogen compoundGO:19016981840.012
regulation of actin filament based processGO:00329701410.012
positive regulation of cellular component movementGO:00512721810.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
specification of organ identityGO:001009230.012
purine ribonucleoside monophosphate catabolic processGO:00091691580.012
establishment of tissue polarityGO:000716430.012
regulation of dna metabolic processGO:00510521530.012
peptidyl tyrosine modificationGO:00182121700.012
negative regulation of transferase activityGO:00513481240.012
establishment or maintenance of apical basal cell polarityGO:003508820.012
regulation of protein complex assemblyGO:00432541470.012
sleepGO:003043120.012
somatic muscle developmentGO:000752510.012
positive regulation of ras gtpase activityGO:00323201170.012
alcohol metabolic processGO:00060661140.012
atp catabolic processGO:00062001570.012
mitotic cell cycle phase transitionGO:00447721620.012
negative regulation of protein maturationGO:19033181420.012
meiotic chromosome segregationGO:004513240.012
cellular response to growth factor stimulusGO:00713631970.012
purine nucleoside monophosphate catabolic processGO:00091281580.012
cdc42 protein signal transductionGO:003248840.012
positive regulation of protein transportGO:00512221350.012
plasma membrane organizationGO:00070091150.012
calcium ion transportGO:00068161470.012
glycerolipid metabolic processGO:00464861070.012
response to hormoneGO:00097251750.012
regulation of dephosphorylationGO:0035303960.012
glial cell migrationGO:000834740.012
melanin metabolic processGO:000658210.011
meiosis iGO:000712740.011
circulatory system developmentGO:00723592620.011
regulation of cell adhesionGO:00301551660.011
monocarboxylic acid biosynthetic processGO:0072330670.011
positive regulation of immune responseGO:00507781590.011
sensory perception of painGO:001923340.011
establishment of protein localization to membraneGO:00901501210.011
glycoprotein biosynthetic processGO:0009101910.011
regulation of meiosisGO:004002030.011
peptidyl tyrosine phosphorylationGO:00181081700.011
central nervous system developmentGO:00074171230.011
viral processGO:00160321460.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
regulation of membrane potentialGO:0042391950.011
protein acylationGO:00435431380.011
defense response to fungusGO:005083240.011
negative regulation of proteolysisGO:00458611320.011
positive regulation of proteolysisGO:00458621420.011
t cell differentiation in thymusGO:003307740.011
positive regulation of cell motilityGO:20001471770.011
fatty acid metabolic processGO:00066311150.011
immune effector processGO:00022521590.011
epidermis morphogenesisGO:004873030.011
protein autophosphorylationGO:00467771230.011
behavioral response to ethanolGO:004814920.011
positive regulation of locomotionGO:00400171860.011
small molecule catabolic processGO:0044282920.011
somatic stem cell divisionGO:004810310.011
g protein coupled receptor signaling pathwayGO:00071862070.011
regulation of defense responseGO:00313471540.011
positive regulation of gliogenesisGO:001401540.011
engulfment of apoptotic cellGO:004365220.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
regulation of wnt signaling pathwayGO:00301111230.011
response to woundingGO:00096111680.011
response to virusGO:00096151260.011
hemopoiesisGO:00300971800.011
coenzyme metabolic processGO:0006732650.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
developmental programmed cell deathGO:001062330.011
regulation of hormone levelsGO:00108171250.011
muscle contractionGO:0006936730.011
forebrain neuron differentiationGO:002187930.011
somatic stem cell maintenanceGO:003501940.011
eye photoreceptor cell differentiationGO:000175420.011
regulation of axon guidanceGO:190266730.011
neuron differentiationGO:00301821380.011
cell substrate adhesionGO:00315891320.011
nucleus localizationGO:005164710.011
calcium ion homeostasisGO:00550741220.011
synaptic vesicle recyclingGO:003646530.010
muscle system processGO:0003012810.010
negative regulation of catabolic processGO:00098951040.010
regulation of glial cell differentiationGO:004568530.010
peptidyl lysine modificationGO:00182051440.010
i kappab kinase nf kappab signalingGO:00072491660.010
sensory perceptionGO:00076001030.010
cardiac muscle contractionGO:0060048340.010
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.010
positive regulation of neural precursor cell proliferationGO:200017920.010
striated muscle contractionGO:0006941520.010
neural crest cell developmentGO:001403230.010
retinal ganglion cell axon guidanceGO:003129020.010
neuron projection regenerationGO:003110210.010
regulation of intracellular protein transportGO:00331571230.010

PPM1H disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.031
nervous system diseaseDOID:8634310.027
sensory system diseaseDOID:00501552030.027
inherited metabolic disorderDOID:6552420.027
musculoskeletal system diseaseDOID:172230.026
central nervous system diseaseDOID:3311860.024
disease of cellular proliferationDOID:145661740.020
cancerDOID:1621670.020
eye diseaseDOID:56141490.019
eye and adnexa diseaseDOID:14921500.019
organ system cancerDOID:00506861640.019
connective tissue diseaseDOID:651090.016
immune system diseaseDOID:29141550.016
retinal diseaseDOID:56791180.015
neurodegenerative diseaseDOID:12891020.014
muscle tissue diseaseDOID:661130.014
muscular diseaseDOID:00800001140.014
myopathyDOID:4231040.014
bone diseaseDOID:0080001880.014
cardiovascular system diseaseDOID:12871060.014
brain diseaseDOID:936730.012
retinal degenerationDOID:8466890.012
hematopoietic system diseaseDOID:741000.012
disease of mental healthDOID:150700.012
heart diseaseDOID:114680.012
amino acid metabolic disorderDOID:9252500.011