Homo sapiens

212 known processes

CHEK2

CHK2 checkpoint homolog (S. pombe)

(Aliases: PP1425,CDS1,CHK2,RAD53,HuCds1,LFS2)

CHEK2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069743791.000
double strand break repairGO:00063021010.993
dna repairGO:00062811980.992
dna damage induced protein phosphorylationGO:000697550.968
regulation of cell cycleGO:00517263930.964
histone h3 acetylationGO:0043966450.963
dna integrity checkpointGO:0031570710.960
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.958
negative regulation of mitotic cell cycleGO:00459301020.955
intrinsic apoptotic signaling pathwayGO:00971931270.918
male meiosisGO:000714010.917
negative regulation of cell cycle phase transitionGO:1901988890.901
regulation of mitotic cell cycleGO:00073461890.898
dna damage checkpointGO:0000077680.895
negative regulation of cell cycleGO:00457861930.892
developmental programmed cell deathGO:001062330.887
Fly
g1 s transition of mitotic cell cycleGO:0000082780.886
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.844
dna damage response signal transduction by p53 class mediatorGO:0030330440.838
chromatin organizationGO:00063253510.831
signal transduction by p53 class mediatorGO:0072331720.829
Fly
double strand break repair via homologous recombinationGO:0000724500.821
regulation of cell cycle phase transitionGO:19019871260.807
regulation of cell cycle processGO:00105642660.804
response to radiationGO:00093141510.796
Mouse Fly
signal transduction in response to dna damageGO:0042770570.752
nuclear divisionGO:00002801280.750
mitotic dna damage checkpointGO:0044773280.748
response to organic cyclic compoundGO:00140702040.744
histone threonine phosphorylationGO:003540570.735
spindle assemblyGO:0051225290.730
chromatin modificationGO:00165682980.714
apoptotic signaling pathwayGO:00971902680.713
chromosome segregationGO:00070591140.703
Worm
positive regulation of cell cycle processGO:00900681060.700
post embryonic developmentGO:000979120.692
regulation of g1 s transition of mitotic cell cycleGO:2000045400.684
cell cycle checkpointGO:00000751170.676
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332370.674
Fly
negative regulation of cell cycle processGO:00109481210.666
mitotic dna integrity checkpointGO:0044774300.663
internal peptidyl lysine acetylationGO:0018393970.660
dna geometric changeGO:0032392320.637
double strand break repair via single strand annealingGO:004500240.609
positive regulation of cysteine type endopeptidase activityGO:2001056790.597
Fly
mitotic g1 dna damage checkpointGO:0031571170.596
cellular protein catabolic processGO:00442572610.596
histone modificationGO:00165702510.584
dna dependent dna replicationGO:0006261440.581
positive regulation of cell cycleGO:00457871400.579
histone h4 acetylationGO:0043967470.572
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.565
cellular response to caffeineGO:007131330.551
recombinational repairGO:0000725500.551
positive regulation of meiotic cell cycleGO:005144620.519
regulation of cell cycle arrestGO:0071156360.510
negative regulation of mitotic cell cycle phase transitionGO:1901991850.482
mitotic centrosome separationGO:000710010.480
g1 dna damage checkpointGO:0044783180.470
regulation of cellular response to stressGO:00801352440.460
Fly
protein modification by small protein conjugationGO:00324463420.457
regulation of mitotic cell cycle phase transitionGO:19019901180.455
mitotic cell cycle checkpointGO:0007093680.447
meiotic chromosome segregationGO:004513240.442
Worm
proteolysis involved in cellular protein catabolic processGO:00516032440.441
covalent chromatin modificationGO:00165692540.433
microtubule cytoskeleton organizationGO:00002261760.432
signal transduction involved in cell cycle checkpointGO:0072395160.419
positive regulation of cell cycle arrestGO:0071158230.406
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediatorGO:0042771230.400
g2 dna damage checkpointGO:0031572260.390
negative regulation of cell proliferationGO:00082852280.381
mitotic g1 s transition checkpointGO:0044819170.376
mitotic cell cycle phase transitionGO:00447721620.373
regulation of cell morphogenesisGO:00226041530.372
endomembrane system organizationGO:00102561960.363
zymogen activationGO:0031638700.361
Fly
regulation of response to dna damage stimulusGO:2001020940.354
Fly
negative regulation of cell cycle g1 s phase transitionGO:1902807290.349
ubiquitin dependent protein catabolic processGO:00065112060.346
protein ubiquitinationGO:00165673140.341
cellular amine metabolic processGO:0044106410.327
chemical homeostasisGO:00488783060.321
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrestGO:000697790.318
dna recombinationGO:0006310770.318
dna double strand break processingGO:0000729100.315
lipid biosynthetic processGO:00086101770.313
cell cycle phase transitionGO:00447701730.309
dna duplex unwindingGO:0032508300.305
cellular homeostasisGO:00197251960.304
regulation of proteolysisGO:00301622930.302
Fly
internal protein amino acid acetylationGO:00064751010.289
nucleotide excision repairGO:0006289310.286
mitotic cell cycleGO:00002783260.279
regulation of mitosisGO:0007088630.276
regulation of cytokinesisGO:0032465450.274
cellular chemical homeostasisGO:00550821800.272
dna catabolic processGO:0006308490.271
dna catabolic process exonucleolyticGO:0000738170.270
regulation of cell developmentGO:00602841610.268
positive regulation of peptidase activityGO:0010952880.268
Fly
regulation of kinase activityGO:00435493140.260
female gamete generationGO:000729220.252
signal transduction involved in mitotic g1 dna damage checkpointGO:0072431100.247
cytokinesisGO:0000910960.247
cell divisionGO:00513011680.238
negative regulation of cell deathGO:00605483450.237
membrane organizationGO:00610242920.237
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.236
golgi disassemblyGO:009016620.235
response to caffeineGO:003100030.234
cellular response to uvGO:0034644320.232
negative regulation of protein metabolic processGO:00512483910.231
positive regulation of proteolysisGO:00458621420.224
Fly
cellular response to purine containing compoundGO:007141530.221
positive regulation of cell proliferationGO:00082843010.219
signal transduction involved in dna damage checkpointGO:0072422150.217
modification dependent protein catabolic processGO:00199412090.215
guanosine containing compound catabolic processGO:19010692390.213
regulation of meiotic cell cycleGO:005144540.210
spindle midzone assemblyGO:005125540.207
regulation of nucleoside metabolic processGO:00091182090.206
protein processingGO:00164852260.204
Fly
signal transduction involved in mitotic dna integrity checkpointGO:1902403130.203
purine nucleoside triphosphate catabolic processGO:00091463920.201
intracellular signal transduction involved in g1 dna damage checkpointGO:1902400100.192
dna conformation changeGO:00711031130.187
negative regulation of phosphorylationGO:00423261740.185
regenerationGO:003109940.182
signal transduction involved in mitotic cell cycle checkpointGO:0072413130.181
response to purine containing compoundGO:0014074400.180
regulation of cell cycle g1 s phase transitionGO:1902806420.179
response to xenobiotic stimulusGO:0009410300.177
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.177
circadian regulation of gene expressionGO:003292280.176
small gtpase mediated signal transductionGO:0007264780.176
peptidyl threonine phosphorylationGO:0018107410.176
androgen biosynthetic processGO:000670230.172
peptidyl lysine acetylationGO:00183941010.172
determination of adult lifespanGO:000834020.172
peptidyl serine phosphorylationGO:00181051010.172
cell cycle g1 s phase transitionGO:0044843800.169
centrosome separationGO:005129930.159
single organism membrane organizationGO:00448022680.158
blastocyst developmentGO:000182430.156
organelle disassemblyGO:190300890.151
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079360.150
cation homeostasisGO:00550801890.150
peptidyl lysine modificationGO:00182051440.149
dna replicationGO:00062601160.147
modification dependent macromolecule catabolic processGO:00436322120.145
negative regulation of transcription involved in g1 s transition of mitotic cell cycleGO:007193020.143
cellular component morphogenesisGO:00329893140.142
organelle fissionGO:00482851490.142
spindle organizationGO:0007051530.139
mitotic cell cycle processGO:19030472860.139
protein acylationGO:00435431380.139
response to nitrogen compoundGO:19016981840.137
protein catabolic processGO:00301633250.134
regulation of dna metabolic processGO:00510521530.134
negative regulation of transferase activityGO:00513481240.133
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.131
regulation of microtubule based processGO:0032886740.129
proteasomal protein catabolic processGO:00104981760.128
cell cycle arrestGO:0007050710.124
cellular response to light stimulusGO:0071482340.121
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.121
Fly
anatomical structure formation involved in morphogenesisGO:00486462840.119
meiosis iGO:000712740.118
actin filament organizationGO:00070151280.118
negative regulation of phosphorus metabolic processGO:00105632670.117
oocyte differentiationGO:000999420.116
cellular response to radiationGO:0071478650.116
Fly
oocyte maturationGO:000155610.115
glycoprotein biosynthetic processGO:0009101910.113
regulation of centrosome cycleGO:0046605150.112
ion homeostasisGO:00508012300.112
regulation of cellular component biogenesisGO:00440872810.108
regulation of transferase activityGO:00513383550.108
purine ribonucleoside metabolic processGO:00461284370.107
heart developmentGO:0007507950.106
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.105
posttranscriptional regulation of gene expressionGO:00106082130.104
metal ion homeostasisGO:00550651690.104
response to hypoxiaGO:0001666960.103
ribonucleoside catabolic processGO:00424544060.101
negative regulation of cellular protein metabolic processGO:00322693530.100
regulation of cell divisionGO:00513021160.098
regulation of protein localizationGO:00328802960.097
regulation of cell diameterGO:006030510.096
negative regulation of proteolysisGO:00458611320.095
ras protein signal transductionGO:0007265730.094
regulation of protein ubiquitinationGO:0031396950.094
embryo developmentGO:00097901230.094
Worm
positive regulation of endopeptidase activityGO:0010950840.093
Fly
response to abiotic stimulusGO:00096283360.092
Mouse Fly
protein acetylationGO:00064731160.092
cellular macromolecule catabolic processGO:00442653800.091
positive regulation of hydrolase activityGO:00513453310.090
Fly
histone phosphorylationGO:0016572160.090
cellular lipid metabolic processGO:00442553030.089
regulation of cellular amine metabolic processGO:0033238110.088
regulation of organelle assemblyGO:1902115400.087
non recombinational repairGO:0000726140.086
signal transduction by phosphorylationGO:00230142970.085
regulation of double strand break repairGO:2000779220.084
single organism cellular localizationGO:19025803320.083
peptidyl threonine modificationGO:0018210450.082
negative regulation of cellular component organizationGO:00511292350.081
rhythmic behaviorGO:000762220.080
i kappab kinase nf kappab signalingGO:00072491660.080
signal transduction involved in dna integrity checkpointGO:0072401150.078
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.076
Fly
microtubule based processGO:00070172100.075
regulation of signal transduction by p53 class mediatorGO:1901796260.075
positive regulation of defense responseGO:0031349870.074
meiotic chromosome separationGO:005130730.073
secretionGO:00469032540.073
negative regulation of phosphate metabolic processGO:00459362670.071
response to organonitrogen compoundGO:00102431560.070
glycoprotein metabolic processGO:00091001100.070
ribonucleoside monophosphate metabolic processGO:00091611870.070
organelle inheritanceGO:004830820.069
morphogenesis of a branching epitheliumGO:0061138200.069
calcium ion homeostasisGO:00550741220.069
regulation of innate immune responseGO:0045088970.066
vesicle mediated transportGO:00161923710.066
positive regulation of phosphorylationGO:00423273940.066
reproductive processGO:00224141060.066
Fly
regulation of protein stabilityGO:0031647870.066
regulation of protein serine threonine kinase activityGO:00719001790.065
negative regulation of catalytic activityGO:00430863350.065
nervous system developmentGO:00073992930.063
response to ionizing radiationGO:0010212650.063
Mouse Fly
negative regulation of kinase activityGO:00336731060.062
regulation of cellular ketone metabolic processGO:0010565500.062
negative regulation of response to dna damage stimulusGO:2001021330.062
regulation of cytoskeleton organizationGO:00514931770.061
guanosine containing compound metabolic processGO:19010682440.060
male gonad developmentGO:0008584230.060
cell developmentGO:00484683280.060
Fly
cellular ketone metabolic processGO:0042180800.059
peptidyl serine modificationGO:00182091060.059
regulation of locomotionGO:00400123290.059
negative regulation of protein phosphorylationGO:00019331400.059
amine metabolic processGO:0009308440.057
regulation of intracellular protein transportGO:00331571230.057
cytokine mediated signaling pathwayGO:00192211090.056
lipid metabolic processGO:00066293810.055
cellular amino acid metabolic processGO:00065201160.055
cellular response to organic cyclic compoundGO:00714071270.055
negative regulation of programmed cell deathGO:00430693210.055
reciprocal dna recombinationGO:003582540.054
regulation of microtubule cytoskeleton organizationGO:0070507610.053
protein polyubiquitinationGO:00002091100.053
development of primary sexual characteristicsGO:0045137350.053
negative regulation of apoptotic processGO:00430663160.052
regulation of histone acetylationGO:0035065190.052
mitotic sister chromatid segregationGO:0000070530.052
purine ribonucleoside triphosphate metabolic processGO:00092054110.052
signal transduction in absence of ligandGO:0038034220.051
positive regulation of nucleotide metabolic processGO:00459812300.051
cellular response to hypoxiaGO:0071456510.051
positive regulation of protein phosphorylationGO:00019343130.051
nucleotide catabolic processGO:00091664080.051
positive regulation of response to dna damage stimulusGO:2001022430.051
urogenital system developmentGO:0001655650.050
regulation of double strand break repair via homologous recombinationGO:0010569110.049
positive regulation of apoptotic signaling pathwayGO:2001235700.049
positive regulation of cell divisionGO:0051781590.049
negative regulation of protein modification processGO:00314002000.049
limbic system developmentGO:002176130.048
maintenance of locationGO:00512351120.048
resolution of meiotic recombination intermediatesGO:000071230.048
response to decreased oxygen levelsGO:0036293960.048
dephosphorylationGO:00163112090.048
cytoplasmic transportGO:00164823790.048
reproductive structure developmentGO:0048608550.048
regulation of cytoplasmic transportGO:19036491490.047
reproductive system developmentGO:0061458560.047
response to drugGO:0042493810.047
protein localization to organelleGO:00333652800.046
response to uvGO:0009411730.046
purine nucleoside catabolic processGO:00061523980.046
regulation of secretion by cellGO:19035301770.046
regulation of endopeptidase activityGO:00525481700.045
Fly
developmental process involved in reproductionGO:0003006660.045
Fly
cellular response to lipidGO:00713961270.044
regulation of protein modification by small protein conjugation or removalGO:19033201070.044
negative regulation of organelle organizationGO:00106391260.043
cellular component disassemblyGO:0022411920.043
rhythmic processGO:0048511310.043
nucleoside triphosphate metabolic processGO:00091414220.043
regulation of anatomical structure morphogenesisGO:00226032860.042
negative regulation of lipid metabolic processGO:0045833380.042
immune response activating signal transductionGO:0002757900.042
embryo development ending in birth or egg hatchingGO:0009792340.041
Worm
regulation of cellular protein catabolic processGO:1903362960.041
g2 m transition of mitotic cell cycleGO:0000086410.041
positive regulation of cellular component organizationGO:00511303760.040
positive regulation of cytoskeleton organizationGO:0051495830.039
regulation of mitotic metaphase anaphase transitionGO:0030071260.039
nucleoside triphosphate catabolic processGO:00091433940.039
protein import into nucleusGO:00066061040.039
interleukin 1 productionGO:0032612260.039
morphogenesis of a branching structureGO:0001763210.038
cellular cation homeostasisGO:00300031630.038
dna catabolic process endonucleolyticGO:0000737370.038
response to light stimulusGO:0009416870.038
angiogenesisGO:00015251470.038
regulation of centrosome duplicationGO:0010824140.038
regulation of protein kinase activityGO:00458592890.037
negative regulation of peptidase activityGO:0010466910.037
cellular metal ion homeostasisGO:00068751460.037
response to toxic substanceGO:0009636370.036
apoptotic process involved in morphogenesisGO:006056130.036
protein maturationGO:00516042330.036
Fly
cellular ion homeostasisGO:00068731680.036
positive regulation of ras gtpase activityGO:00323201170.036
microtubule nucleationGO:000702060.036
activation of cysteine type endopeptidase activityGO:0097202570.036
Fly
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.036
positive regulation of transportGO:00510503360.035
positive regulation of transferase activityGO:00513472270.035
regulation of actin cytoskeleton organizationGO:00329561160.035
regulation of peptidase activityGO:00525471800.035
Fly
neuromuscular junction developmentGO:000752830.034
positive regulation of cell morphogenesis involved in differentiationGO:0010770500.034
positive regulation of dendrite morphogenesisGO:005077530.034
purine nucleoside monophosphate metabolic processGO:00091261860.034
nucleoside phosphate catabolic processGO:19012924120.033
circadian rhythmGO:0007623210.033
response to reactive oxygen speciesGO:0000302610.033
triglyceride homeostasisGO:0070328140.033
golgi inheritanceGO:004831320.033
single organism reproductive processGO:0044702980.032
Fly
microtubule organizing center organizationGO:0031023620.032
circulatory system developmentGO:00723592620.032
regulation of establishment of protein localizationGO:00702012420.032
negative regulation of mitosisGO:0045839240.031
cell adhesionGO:00071553250.031
neutrophil aggregationGO:007048820.031
response to oxygen levelsGO:00704821000.031
ribonucleoside triphosphate metabolic processGO:00091994120.031
regulation of leukocyte proliferationGO:0070663670.031
regulation of defense responseGO:00313471540.030
positive regulation of cellular protein catabolic processGO:1903364370.030
circadian behaviorGO:004851220.030
response to transition metal nanoparticleGO:1990267290.030
ribonucleotide catabolic processGO:00092614050.030
base excision repairGO:0006284210.030
cell morphogenesis involved in differentiationGO:00009041440.029
histone acetylationGO:0016573930.029
protein heterotetramerizationGO:005129030.029
reciprocal meiotic recombinationGO:000713140.029
central nervous system developmentGO:00074171230.029
rho protein signal transductionGO:0007266260.028
regulation of cellular amino acid metabolic processGO:000652160.028
reproductionGO:0000003630.028
Worm Fly
organelle assemblyGO:00709251760.028
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.028
centrosome duplicationGO:0051298280.028
cell cell signalingGO:00072671550.028
protein oligomerizationGO:00512591730.028
oogenesisGO:004847720.028
response to alkaloidGO:0043279200.028
positive regulation of dna repairGO:0045739250.028
brain developmentGO:0007420970.028
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.027
positive regulation of fibroblast proliferationGO:0048146210.027
cell part morphogenesisGO:00329901370.027
positive regulation of protein kinase activityGO:00458601900.027
gtp metabolic processGO:00460392390.027
negative regulation of cell divisionGO:0051782310.027
response to fungusGO:000962040.026
negative regulation of lipid kinase activityGO:009021930.026
histone h3 k9 modificationGO:0061647110.026
positive regulation of cellular catabolic processGO:00313312840.026
response to lipidGO:00339932060.026
regulation of mononuclear cell proliferationGO:0032944650.026
histone serine phosphorylationGO:003540440.026
protein targeting to nucleusGO:00447441040.026
golgi organizationGO:0007030380.025
gonad developmentGO:0008406340.025
regulation of i kappab kinase nf kappab signalingGO:00431221620.025
regulation of circadian rhythmGO:0042752110.025
glycosyl compound catabolic processGO:19016584130.025
cellular response to iron ionGO:007128110.025
pattern specification processGO:0007389430.025
hippocampus developmentGO:002176610.025
regulation of protein catabolic processGO:00421761550.025
mammary gland developmentGO:0030879170.025
cellular response to endogenous stimulusGO:00714953360.025
centrosome organizationGO:0051297580.025
regulation of nucleocytoplasmic transportGO:0046822980.024
regulation of protein dephosphorylationGO:0035304180.024
divalent inorganic cation homeostasisGO:00725071360.024
regulation of dna damage response signal transduction by p53 class mediatorGO:0043516200.024
lens development in camera type eyeGO:000208820.024
glycogen biosynthetic processGO:0005978160.024
negative regulation of glycoprotein metabolic processGO:190301980.024
anatomical structure homeostasisGO:00602491000.024
adherens junction organizationGO:0034332360.023
glycerolipid metabolic processGO:00464861070.023
protein deubiquitinationGO:0016579790.023
protein destabilizationGO:0031648120.023
branching morphogenesis of an epithelial tubeGO:0048754190.023
negative regulation of protein serine threonine kinase activityGO:0071901570.023
mitotic nuclear divisionGO:00070671190.023
purine nucleoside triphosphate metabolic processGO:00091444120.022
positive regulation of cytokinesisGO:0032467290.022
purine ribonucleotide catabolic processGO:00091544040.022
cell morphogenesisGO:00009022960.022
gtp catabolic processGO:00061842370.022
regulation of cellular component sizeGO:0032535820.022
cellular response to abiotic stimulusGO:00712141170.022
Fly
regulation of viral processGO:00507921030.022
oocyte developmentGO:004859910.022
actin filament bundle assemblyGO:0051017540.022
regulation of protein targetingGO:1903533910.022
intracellular protein transportGO:00068862700.022
centrosome cycleGO:0007098320.022
protein targetingGO:00066051870.022
negative regulation of g2 m transition of mitotic cell cycleGO:001097290.022
regulation of protein transportGO:00512232130.021
regulation of transcription by chromatin organizationGO:003440110.021
meiotic nuclear divisionGO:0007126100.021
Worm
transcription factor import into nucleusGO:0042991400.021
carbohydrate metabolic processGO:00059752070.021
peptidyl tyrosine dephosphorylationGO:0035335360.021
oxidation reduction processGO:00551143960.021
regulation of cell substrate adhesionGO:0010810680.021
nucleic acid phosphodiester bond hydrolysisGO:00903051020.021
interleukin 1 alpha secretionGO:005070310.021
positive regulation of programmed cell deathGO:00430682490.021
Fly
nucleus organizationGO:0006997280.020
response to steroid hormoneGO:0048545800.020
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoterGO:007236610.020
endocytosisGO:00068971590.020
purine nucleoside monophosphate catabolic processGO:00091281580.020
defense response to fungusGO:005083240.020
positive regulation of catabolic processGO:00098963100.020
cell cycle g2 m phase transitionGO:0044839430.020
regulation of nervous system developmentGO:0051960880.020
chromosome separationGO:0051304230.020
positive regulation of dna damage response signal transduction by p53 class mediatorGO:004351780.020
response to tumor necrosis factorGO:0034612760.020
positive regulation of multi organism processGO:0043902560.020
regulation of cell morphogenesis involved in differentiationGO:0010769830.020
regulation of protein import into nucleusGO:0042306780.020
negative regulation of cell cycle g2 m phase transitionGO:1902750100.020
anterior posterior axis specificationGO:000994820.020
cellular divalent inorganic cation homeostasisGO:00725031280.019
negative regulation of protein ubiquitinationGO:0031397350.019
response to oxygen containing compoundGO:19017003690.019
chromatin mediated maintenance of transcriptionGO:004809620.019
locomotory behaviorGO:000762610.019
tube developmentGO:00352951250.019
centriole replicationGO:0007099130.019
hexose metabolic processGO:0019318550.019
regulation of neuron projection developmentGO:0010975570.019
apoptotic mitochondrial changesGO:0008637570.019
single organismal cell cell adhesionGO:00163371480.019
negative regulation of protein processingGO:00109551420.019
positive regulation of cell deathGO:00109422630.019
Fly
cardiac chamber developmentGO:0003205300.019
regulation of sequence specific dna binding transcription factor activityGO:00510902110.019
Fly
negative regulation of protein kinase activityGO:0006469980.018
positive regulation of mitotic cell cycleGO:0045931600.018
cation transportGO:00068123310.018
cell growthGO:00160491600.018
renal system developmentGO:0072001630.018
negative regulation of neural precursor cell proliferationGO:200017810.018
regulation of neuron differentiationGO:0045664700.018

CHEK2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.907
cancerDOID:1621670.907
organ system cancerDOID:00506861640.672
immune system diseaseDOID:29141550.386
aplastic anemiaDOID:12449300.200
anemiaDOID:2355550.200
bone marrow diseaseDOID:4961310.200
hematopoietic system diseaseDOID:741000.200
breast cancerDOID:1612210.143
thoracic cancerDOID:5093210.143
congenital hypoplastic anemiaDOID:1342260.100
gastrointestinal system cancerDOID:3119520.042
large intestine cancerDOID:5672290.025
intestinal cancerDOID:10155290.025
colorectal cancerDOID:9256290.025
colon cancerDOID:219250.025
liver carcinomaDOID:68690.022
liver cancerDOID:357190.022
hepatocellular carcinomaDOID:68490.022